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Ovarian tissue cryopreservation

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https://www.readbyqxmd.com/read/29778393/fertility-preservation-in-pediatric-female-cancer-patients
#1
Sara E Arian, Rebecca L Flyckt, Richard Herman, Hadi Erfani, Tommaso Falcone
OBJECTIVE: To describe and demonstrate ovarian tissue cryopreservation (OTC) as an emerging fertility preservation technique DESIGN: Video presentation. SETTING: University hospital. PATIENT(S): A 6 year-old female patient diagnosed with aplastic anemia with plan for bone marrow transplantation underwent laparoscopic unilateral oophorectomy in conjunction with surgical procedure for port placement by the pediatric surgeon, followed by cryopreservation of ovarian tissue...
May 2018: Fertility and Sterility
https://www.readbyqxmd.com/read/29718400/defining-quality-assurance-and-quality-control-measures-in-connection-with-ovarian-tissue-cryopreservation-and-transplantation-a-call-to-action
#2
Claus Yding Andersen, Anne Cathrine Bollerup, Stine Gry Kristensen
Freezing of ovarian tissue for fertility preservation has been gaining ground as a valid method in recent years. More than 100 children have been born from this procedure worldwide. As a result, many fertility clinics are now implementing this method. However, the practical procedures that need to be mastered to successfully implement the freezing of ovarian tissue are different in many aspects from those normally used in fertility clinics and are not well defined. Furthermore, success is difficult to measure since patients usually do not return for transplantation until several years after freezing, which puts extra emphasis of good quality control and quality assurance measures to secure a transplantation of tissue with surviving follicles that can sustain fertility...
April 27, 2018: Human Reproduction
https://www.readbyqxmd.com/read/29704433/retrievable-hydrogels-for-ovarian-follicle-transplantation-and-oocyte-collection
#3
Peter D Rios, Ekaterina Kniazeva, Hoi Chang Lee, Shuo Xiao, Robert S Oakes, Eiji Saito, Jacqueline S Jeruss, Ariella Shikanov, Teresa K Woodruff, Lonnie D Shea
Cancer survivorship rates have drastically increased due to improved efficacy of oncologic treatments. Consequently, clinical concerns have shifted from solely focusing on survival to quality of life, with fertility preservation as an important consideration. Among fertility preservation strategies for female patients, ovarian tissue cryopreservation and subsequent re-implantation has been the only clinical option available to cancer survivors with cryopreserved tissue. However, follicle atresia post-transplantation and risk of re-introducing malignant cells have prevented this procedure from becoming widely adopted in clinics...
April 28, 2018: Biotechnology and Bioengineering
https://www.readbyqxmd.com/read/29700601/attitude-towards-ovarian-tissue-and-oocyte-cryopreservation-for-non-medical-reasons-a-cross-sectional-study
#4
Nada Woodtli, Michael von Wolff, Norman Bitterlich, Petra Stute
PURPOSE: To assess the attitude towards ovarian tissue and oocyte cryopreservation for non-medical reasons. METHODS: Cross-sectional electronic survey in 248 Swiss women aged 15-35 years, nationally representative for educational level. RESULTS: Most women did not worry about an age-related fertility decline. Two-thirds of women would consider using hormone therapy (HT) for menopausal symptom relief although concerns about side effects and risks were still high...
April 26, 2018: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29696942/challenges-of-fertility-preservation-in-leukemia-patients
#5
Moran Shapira, Hila Raanani, Sanaz Derech Chaim, Dror Meirow
An ongoing increase in survival rates among young leukemia patients is accompanied by a growing attention to possible long-term complications such as chemotherapy induced ovarian insufficiency and infertility. Therefore, an important element of the management of these patients is fertility preservation, which is challenged by considerations specific for leukemia. Such considerations include prepuberty, poor medical condition on presentation and the need for urgent chemotherapy, all of which may preclude the use of conventional assisted reproductive technologies...
April 24, 2018: Minerva Ginecologica
https://www.readbyqxmd.com/read/29696941/successful-pregnancy-in-a-woman-previously-suffering-from-%C3%AE-thalassaemia-following-transplantation-of-ovarian-tissue-cryopreserved-before-puberty
#6
Sara J Matthews, Helen M Picton, Erik Ernst, Claus Y Andersen
Ovarian tissue removed from a nine year old girl suffering from thalassemia was kept deep- frozen for 14 years before being transplanted back to the now adult woman. Subsequently, she conceived following IVF treatment and delivered a healthy baby where the oocyte derived from the transplanted tissue. This is the first woman worldwide to have a baby where the ovarian tissue was frozen pre-pubertally and expand the therapeutic options for rare genetic diseases like thalassemia and girls who suffer from childhood cancer...
April 24, 2018: Minerva Ginecologica
https://www.readbyqxmd.com/read/29691062/pediatric-ovarian-tissue-cryopreservation-time-to-lift-the-experimental-label
#7
EDITORIAL
Mindy S Christianson, Steven R Lindheim
No abstract text is available yet for this article.
April 21, 2018: Fertility and Sterility
https://www.readbyqxmd.com/read/29644333/risk-of-transplanting-malignant-cells-in-cryopreserved-ovarian-tissue
#8
Marie-Madeleine Dolmans, Rossella Masciangelo
Improvements in cancer treatments have increased the chances of survival of young cancer patients, but have given rise to other issues, like premature ovarian insufficiency and infertility. Preservation and subsequent restoration of ovarian function in these patients is now possible thanks to ovarian tissue cryopreservation and transplantation. However, safety concerns about the possible presence of cancerous cells in the tissue to be cryopreserved must be addressed. Indeed, reimplantation of malignant cell-contaminated ovarian tissue could potentially lead to recurrence of the primary disease...
April 11, 2018: Minerva Ginecologica
https://www.readbyqxmd.com/read/29644332/indications-for-fertility-preservation-in-women-from-malignant-diseases-to-benign-conditions-to-age-related-fertility-decline
#9
Marie-Madeleine Dolmans, Jacques Donnez
Oocyte vitrification and ovarian tissue cryopreservation are 2 common fertility preservation options. Oocyte vitrification provides the highest yield for women with benign diseases or those seeking fertility preservation for age-related fertility decline. This technique is also indicated for cancer women if cancer treatment can be post-poned. Ovarian tissue cryopreservation has some specific indications. There is indeed no other alternative for fertility preservation in prepubertal girls, adolescents and cancer women in whom cancer treatment cannot be postponed...
April 11, 2018: Minerva Ginecologica
https://www.readbyqxmd.com/read/29644331/from-isolation-of-human-ovarian-follicles-to-the-artificial-ovary-tips-and-tricks
#10
Maria C Chiti, Jacques Donnez, Christiani Andrade Amorim, Marie-Madeleine Dolmans
Cryopreservation and transplantation of ovarian tissue has proved to restore both endocrine and reproductive functions in cancer patients. However women with a high risk of ovarian involvement cannot undergo ovarian tissue transplantation due to possible recurrence of the disease. Therefore, different teams worldwide are now working on the development of experimental strategies, like the transplantable artificial ovary (TAO), with the noble goal to offer to these patients hope for future conception. This article discusses some essential points for the creation of a TAO and reviews the latest progress made...
April 11, 2018: Minerva Ginecologica
https://www.readbyqxmd.com/read/29644329/fertility-preservation-in-women-with-ovarian-endometriosis
#11
Jacques Donnez, Javier García-Solares, Marie-Madeleine Dolmans
Endometriosis is a frequently encountered benign gynecological disease that may be responsible for infertility. Treatment of endometriosis-associated infertility has been investigated using both medical and surgical therapeutic modalities. Therapy has essentially three main objectives: (i) to preserve and improve fertility, (ii) to reduce pain, and (iii) to delay recurrence. The aim of this paper is to focus on fertility preservation in women with severe endometriosis. In ovarian endometriosis-associated infertility, a medico-surgical approach remains the gold standard, but more and more papers are reporting a low ovarian reserve after laparoscopic cystectomy for endometriomas...
April 11, 2018: Minerva Ginecologica
https://www.readbyqxmd.com/read/29644328/techniques-for-ovarian-tissue-transplantation-and-results
#12
Jacques Donnez, Diego D Manavella, Marie-Madeleine Dolmans
Fertility preservation has emerged as a field of growing interest thanks to increasingly effective cancer treatments in women. For young women with good prospects of surviving cancer, fertility preservation counseling before gonadotoxic treatment is imperative to offer them a potential chance of future childbearing. Ovarian tissue cryopreservation and transplantation rises as a strategy for fertility preservation, especially for prepubertal girls, adolescents and women in whom cancer treatment cannot be delayed...
April 11, 2018: Minerva Ginecologica
https://www.readbyqxmd.com/read/29620997/fertility-preservation-in-patients-with-cancer-asco-clinical-practice-guideline-update
#13
Kutluk Oktay, Brittany E Harvey, Ann H Partridge, Gwendolyn P Quinn, Joyce Reinecke, Hugh S Taylor, W Hamish Wallace, Erica T Wang, Alison W Loren
Purpose To provide current recommendations about fertility preservation for adults and children with cancer. Methods A systematic review of the literature published from January 2013 to March 2017 was completed using PubMed and the Cochrane Library. An Update Panel reviewed the identified publications. Results There were 61 publications identified and reviewed. None of these publications prompted a significant change in the 2013 recommendations. Recommendations Health care providers should initiate the discussion on the possibility of infertility with patients with cancer treated during their reproductive years or with parents/guardians of children as early as possible...
April 5, 2018: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/29618356/in-vitro-maturation-of-oocytes-from-excised-ovarian-tissue-in-a-patient-with-autoimmune-ovarian-insufficiency-possibly-associated-with-epstein-barr-virus-infection
#14
Irma Virant-Klun, Andrej Vogler
BACKGROUND: Some reports show that it is possible to isolate immature oocytes from human ovarian tissue retrieved by a cortex biopsy or ovariectomy of non-stimulated ovaries and mature them in vitro. The mature oocytes can be vitrified and stored for in vitro fertilization, which, along with ovarian tissue cryopreservation, is mostly practiced in young cancer patients to preserve their fertility. There is much less data on this new approach in women with a natural ovarian insufficiency, which can be caused by different factors, including viral infection...
April 5, 2018: Reproductive Biology and Endocrinology: RB&E
https://www.readbyqxmd.com/read/29607457/preliminary-human-application-of-optical-coherence-tomography-for-quantification-and-localization-of-primordial-follicles-aimed-at-effective-ovarian-tissue-transplantation
#15
Seido Takae, Kosuke Tsukada, Ichiro Maeda, Naoki Okamoto, Yorino Sato, Haruhiro Kondo, Kiemi Shinya, Yuki Motani, Nao Suzuki
PURPOSE: The purpose of this study was to evaluate the possible clinical application of optical coherence tomography for assessing ovarian reserve in individual specimens of human ovarian tissue for fertility preservation. METHODS: Ovarian tissue examination by optical coherence tomography was performed before ovarian tissue cryopreservation. Three of the four subjects had hematological disease or cancer, and they faced a threat to their fertility due to impending chemotherapy...
April 2, 2018: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/29581237/female-fertility-preservation-past-present-and-future
#16
Benjamin Fisch, Ronit Abir
Anti-cancer therapy, particularly chemotherapy damages ovarian follicles and promotes ovarian failure. The only pharmacological means for protecting the ovaries from chemotherapy-induced injury is gonadotrophin-releasing hormone agonist, but its efficiency remains controversial; ovarian transposition is used to shield the ovary from radiation when indicated. Until the late 1990s, the only option for fertility preservation and restoration in women with cancer was embryo cryopreservation. The development of other assisted reproductive technologies such as mature oocyte cryopreservation and in vitro maturation of oocytes has contributed to fertility preservation...
March 26, 2018: Reproduction: the Official Journal of the Society for the Study of Fertility
https://www.readbyqxmd.com/read/29574609/outcome-of-immature-oocytes-collection-of-119-cancer-patients-during-ovarian-tissue-harvesting-for-fertility-preservation
#17
Alon Kedem, Gil M Yerushalmi, Masha Brengauz, Hila Raanani, Raoul Orvieto, Ariel Hourvitz, Dror Meirow
PURPOSE: Few clinical options for fertility preservation are available to females with cancer, and data about clinical outcomes is limited. Potential supplementary approaches to fertility preservation include retrieval of immature oocytes followed by in vitro maturation (IVM) and storage. The aim of this study was to evaluate post-thawing outcomes of immature oocytes collected both by transvaginal aspiration and from excised ovarian tissue. METHODS: We conducted a retrospective cohort study of patients treated in a single tertiary center...
March 24, 2018: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/29574135/cryopreservation-and-in-vitro-culture-of-white-tailed-deer-ovarian-tissue
#18
G D A Gastal, F L N Aguiar, A P R Rodrigues, J M Scimeca, G A Apgar, W J Banz, J M Feugang, E L Gastal
The aims of this study were to evaluate (1) the survivability of white-tailed deer ovarian tissue after cryopreservation by slow-freezing (SF) and vitrification (VIT) techniques and in vitro culture (IVC) for up to 7 days, and (2) the effects of cryopreservation techniques on protein expression of proliferative and apoptotic markers of ovarian tissue pre- and post-in vitro culture. Ovaries (n = 14) of seven white-tailed deer fawns (<1.5 years old) were used. Ovarian cortexes were cut into fragments (2 × 2 × 0...
March 8, 2018: Theriogenology
https://www.readbyqxmd.com/read/29566858/ovarian-tissue-cryopreservation-still-experimental
#19
EDITORIAL
Eric J Forman
No abstract text is available yet for this article.
March 2018: Fertility and Sterility
https://www.readbyqxmd.com/read/29527868/cryobiology-of-ovarian-tissues-known-knowns-and-known-unknowns
#20
Ram V Devireddy
To model the cryobiological responses of cells and tissues, the cellular membrane permeability characteristics are often measured at suprazero temperatures as well as at subzero temperatures with and without the presence of extra-cellular ice. These measured membrane permeability characteristics are then used to predict the responses of cells and tissues for a given thermal insult with the ultimate aim of mitigating the damage caused during the freeze-thaw process. This brief review articles summarizes efforts from my research group over the past 15 years as related to cryobiology of mammalian ovarian tissue sections, i...
March 8, 2018: Minerva Ginecologica
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