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https://www.readbyqxmd.com/read/29776671/guidelines-on-diabetic-eye-care-the-international-council-of-ophthalmology-recommendations-for-screening-follow-up-referral-and-treatment-based-on-resource-settings
#1
REVIEW
Tien Y Wong, Jennifer Sun, Ryo Kawasaki, Paisan Ruamviboonsuk, Neeru Gupta, Van Charles Lansingh, Mauricio Maia, Wanjiku Mathenge, Sunil Moreker, Maji M K Muqit, Serge Resnikoff, Juan Verdaguer, Peiquan Zhao, Frederick Ferris, Lloyd P Aiello, Hugh R Taylor
Diabetes mellitus (DM) is a global epidemic and affects populations in both developing and developed countries, with differing health care and resource levels. Diabetic retinopathy (DR) is a major complication of DM and a leading cause of vision loss in working middle-aged adults. Vision loss from DR can be prevented with broad-level public health strategies, but these need to be tailored to a country's and population's resource setting. Designing DR screening programs, with appropriate and timely referral to facilities with trained eye care professionals, and using cost-effective treatment for vision-threatening levels of DR can prevent vision loss...
May 15, 2018: Ophthalmology
https://www.readbyqxmd.com/read/29774372/-optical-coherence-tomography-for-skin-pathologies
#2
REVIEW
J Welzel, S Schuh
Optical coherence tomography (OCT) has become established in routine diagnosis in dermatology only in the last few years. The reason is that the skin is a challenge for OCT as a strong scattering medium, because only a very small proportion of photons is reflected and can be used for imaging. In addition, in most cases a visual assessment or a biopsy is sufficient. Nevertheless, the main field of application in dermatology is the diagnostics of epithelial skin tumors. The OCT is suitable for the early recognition of small, clinically and light microscopically unspecific basal cell carcinomas as well as for the differential diagnosis of other tumors and precancerous lesions...
May 17, 2018: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/29771749/brillouin-microscopy-assessing-ocular-tissue-biomechanics
#3
Seok Hyun Yun, Dimitri Chernyak
PURPOSE OF REVIEW: Assessment of corneal biomechanics has been an unmet clinical need in ophthalmology for many years. Many researchers and clinicians have identified corneal biomechanics as source of variability in refractive procedures and one of the main factors in keratoconus. However, it has been difficult to accurately characterize corneal biomechanics in patients. The recent development of Brillouin light scattering microscopy heightens the promise of bringing biomechanics into the clinic...
May 15, 2018: Current Opinion in Ophthalmology
https://www.readbyqxmd.com/read/29770858/-management-of-anticoagulants-in-ophthalmic-surgery-a-survey-among-ophthalmic-surgeons-in-germany
#4
N Feltgen, B Mele, T Dietlein, C Erb, A Eckstein, A Hager, A Heiligenhaus, H Helbig, H Hoerauf, E Hoffmann, D Pauleikhoff, M Schittkowski, B Seitz, C Sucker, S Suffo, U Schaudig, F Tost, S Thurau, P Walter, J Koscielny
INTRODUCTION: As our population ages and comorbidities rise, ophthalmic surgeons are increasingly faced with patients on anticoagulant therapy or with clotting disorders. The ophthalmic surgeon has to weigh the perioperative risk of haemorrhage when anticoagulation continues against the risk of thromboembolism caused by discontinuation or changing the patient's medication (bridging, switching, cessation). There are currently no guidelines or recommendations. METHODS: A survey was sent to the DOG (German Ophthalmologic Society) divisions and associated surgical organizations to determine the status quo...
May 16, 2018: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/29721842/pigment-dispersion-syndrome-and-pigmentary-glaucoma-a-review-and-update
#5
Gianluca Scuderi, Maria Teresa Contestabile, Luca Scuderi, Aloisa Librando, Vito Fenicia, Siavash Rahimi
INTRODUCTION: Potential factors influencing stereopsis were investigated in patients with both refractive accommodative esotropia (RAE) and amblyopia. Pigment dispersion syndrome (PDS) is a condition where anomalous iridozonular contact leads to pigment dispersion throughout the anterior segment and the released pigment is abnormally deposited on various ocular structures. CLINICAL PRESENTATION: The clinical presentation of PDS is defined by the presence of pigmented cells on the corneal endothelium, an increase of pigmentation of the trabecular meshwork, and mid-periphery transillumination defects of the iris...
May 2, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29675384/effect-of-anti-vegf-treatment-on-retinopathy-of-prematurity-in-zone-ii-stage-3
#6
Xiu-Mei Yang, Yue-Xiang Zhao, Zong-Hua Wang, Lu Liu
AIM: To evaluate the effect of intravitreal ranibizumab injection for retinopathy of prematurity (ROP) in Zone II Stage 3+ . METHODS: Data was collected for ROP patients with Zone II Stage 3+ who received intravitreal ranibizumab injections between October 2014 and Janu-ary 2017 at the Department of Ophthalmology in our hospital. No prior laser or other intravitreal treatment was done. Prior to the intervention and at each follow-up visit, fundus examination was performed...
2018: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/29661534/a-new-chlorin-formulation-promotes-efficient-photodynamic-action-in-choriocapillaris-of-rabbit-s-eyes
#7
Gustavo H A Salomao, Adjaci U Fernandes, Mauricio S Baptista, João Paulo Tardivo, Stella Gianssante, Juliana Mora Veridiano, Olga Maria S Toledo, Giuliana Petri, Denise Maria Christofolini, João Antonio Correa
Age-related macular degeneration (AMD) as well as other choroidal diseases, demand novel therapeutic methods. Photodynamic therapy (PDT), which uses light and photosensitizer (PS) to cause specific vascular occlusion in the macula, is an interesting alternative. The only drug approved for the PDT treatment of AMD (Verteporfin) has a natural tendency to aggregate, demanding an expensive separation procedure during purification. We report a novel and affordable PS that is intrinsically protected against aggregation, the Monomeric Chlorin at High Concentration (MCHC-Chlorin), whose liposomal formulation was developed to provoke effective photodynamic action on the choroidal vasculature...
April 4, 2018: Bioorganic & Medicinal Chemistry Letters
https://www.readbyqxmd.com/read/29655617/novel-treatment-of-papillomatous-conjunctival-lesions-using-pattern-scanning-laser-photocoagulation-1-year-results
#8
R N Belfort, J Isenberg, A G Castillejos, R Sant'ana, A O Romano
PURPOSE: To evaluate the safety and 1-year effect of pattern scanning laser photocoagulation treatment for pedunculated papillomatous and sessile conjunctival lesions in a low-resource setting with extremely limited operating room access. METHODS: Adult patients with clinical diagnosis of conjunctival papilloma underwent complete ophthalmologic exam including anterior segment photography. After topical anesthesia and toluidine blue 1% instillation, the lesion was treated by pattern scanning photocoagulation using a duration time that varied from 20 to 100 ms and power from 600 to 1800 mW, treating the entire lesion surface with a 2 mm margin...
April 12, 2018: Ocular Surface
https://www.readbyqxmd.com/read/29643779/the-safety-and-effectiveness-of-a-novel-annular-keratopigmentation-method-a-case-report
#9
Francis Ferrari, Robbert van Haselen
Background: We investigated the safety and effectiveness of a novel aesthetic femtosecond-assisted annular keratopigmentation technique. Case Report: A 21-year-old female patient in good general and ophthalmological health with the wish to change the colour of her eyes was treated with a femtosecond-assisted annular keratopigmentation technique. Pigment was inserted in a channel in the cornea (external diameter 9.3 mm; internal diameter 5.5 mm) created with a femtosecond laser at a depth of 225 μm...
January 2018: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/29617855/endoscopic-resection-of-an-intraventricular-tumor-with-second-window-indocyanine-green-2-dimensional-operative-video
#10
Frederick L Hitti, John Y K Lee
A 26-year-old woman presented to our clinic with years of headaches and mental clouding. She had a nonfocal neurological examination including benign ophthalmological examination. Head computed tomography and brain magnetic resonance imaging (MRI) demonstrated asymmetry of the lateral ventricles due to a lesion arising from the foramen of Monro. At the top of our differential diagnosis were choroid plexus tumor and colloid cyst. We offered the patient treatment via an endoscopic approach. Here, we demonstrate the feasibility of using tumor-localizing dyes such as indocyanine green (ICG) in conjunction with endoscopes equipped with lasers to localize and treat intraventricular lesions...
March 29, 2018: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/29610025/comparative-study-of-3-intracorneal-implant-types-to-manage-central-keratoconus
#11
Mohamed Omar Yousif, Azza Mohamed Ahmed Said
PURPOSE: To compare the visual acuity, refraction, corneal topography, and corneal asphericity of intrastromal corneal implantation of Keratacx 160-degree 2 symmetrical ring segment, the Keratacx 320-degree near-total ring, and the Myoring continuous intracorneal ring (ICR) in central keratoconus. SETTING: Ophthalmology Department, Ain Shams University, Cairo, Egypt. DESIGN: Prospective case series. METHODS: Surgeries were performed using a femtosecond laser for tunnel creation for the 160-degree 2-segment device (Group 1) and the 320-degree near-total ring (Group 2), and for pocket creation for the ICR (Group 3)...
March 30, 2018: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/29576875/current-advances-in-pharmacotherapy-and-technology-for-diabetic-retinopathy-a-systematic-review
#12
REVIEW
Lei Lu, Ying Jiang, Ravindran Jaganathan, Yanli Hao
Diabetic retinopathy (DR) is classically defined by its vascular lesions and damage in the neurons of the retina. The cellular and clinical elements of DR have many features of chronic inflammation. Understanding the individual cell-specific inflammatory changes in the retina may lead to novel therapeutic approaches to prevent vision loss. The systematic use of available pharmacotherapy has been reported as a useful adjunct tool to laser photocoagulation, a gold standard therapy for DR. Direct injections or intravitreal anti-inflammatory and antiangiogenesis agents are widely used pharmacotherapy to effectively treat DR and diabetic macular edema (DME)...
2018: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29575657/consensus-on-procedures-to-include-in-a-simulation-based-curriculum-in-ophthalmology-a-national-delphi-study
#13
Ann Sofia Skou Thomsen, Morten la Cour, Charlotte Paltved, Karen Gilboe Lindorff-Larsen, Bjørn Ulrik Nielsen, Lars Konge, Leizl Joy Nayahangan
PURPOSE: The number of available simulation-based models for technical skills training in ophthalmology is rapidly increasing, and development of training programmes around these procedures should follow a structured approach. The aim of this study was to identify all technical procedures that should be integrated in a simulation-based curriculum in ophthalmology. METHODS: Key opinion leaders involved in the education of ophthalmologists in Denmark including heads of departments, heads of clinical education, professors and board members of the society were invited to participate in a three-round Delphi process...
March 25, 2018: Acta Ophthalmologica
https://www.readbyqxmd.com/read/29575612/assessment-of-the-metabolism-and-morphology-of-the-porcine-cornea-lens-and-retina-by-two-photon-imaging
#14
Ana Batista, Hans Georg Breunig, Aisada König, António Miguel Morgado, Karsten König
Two-photon imaging is a non-invasive imaging technique with increasing importance in the biological and medical fields since it allows intratissue cell imaging with high resolution. We demonstrate the feasibility of using a single two-photon instrument to evaluate the cornea, the crystalline lens, and the retina based on their autofluorescence. Image acquisition was performed using a custom-built two-photon microscope for 5D microscopy with a near infrared broadband sub-15 femtosecond laser centered at 800 nm...
March 25, 2018: Journal of Biophotonics
https://www.readbyqxmd.com/read/29522229/predictability-of-tunnel-depth-for-intrastromal-corneal-ring-segments-implantation-between-manual-and-femtosecond-laser-techniques
#15
Tiago Monteiro, José F Alfonso, Nuno Franqueira, Fernando Faria-Correia, Renato Ambrósio, David Madrid-Costa
PURPOSE: To compare the predictability of intrastromal tunnel depth creation for intrastromal corneal ring segments (ICRS) implantation between manual dissection and femtosecond laser using a high-resolution anterior segment optical coherence tomography (AS-OCT). METHODS: This multicenter study included patients with keratoconus who had Ferrara-type ICRS implantation at Hospital de Braga using manual dissection and at the Fernandez-Vega Ophthalmological Institute using the femtosecond laser technique...
March 1, 2018: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/29510401/subclinical-macular-edema-as-a-predictor-of-progression-to-central-involved-macular-edema-in-type-2-diabetes
#16
Conceição Lobo, Isabel Pires, Dalila Alves, Rajeev Pappuru, Luísa Ribeiro, José Cunha-Vaz
PURPOSE: The aim of this study was to examine the relationship between subclinical diabetic macular edema (SCME) and the development of central-involved macular edema (CIME) in patients with diabetes mellitus type-2 and mild nonproliferative diabetic retinopathy (NPDR), from 2 populations of different ethnicities. METHODS: Two hundred and five patients with diabetes mellitus type-2 and mild NPDR with no prior laser or intravitreal treatment were followed for 2 years or until the development of CIME...
March 6, 2018: Ophthalmic Research
https://www.readbyqxmd.com/read/29482864/laser-peripheral-iridotomy-in-primary-angle-closure-a-report-by-the-american-academy-of-ophthalmology
#17
Sunita Radhakrishnan, Philip P Chen, Anna K Junk, Kouros Nouri-Mahdavi, Teresa C Chen
PURPOSE: To examine the efficacy and complications of laser peripheral iridotomy (LPI) in subjects with primary angle closure (PAC). METHODS: Literature searches in the PubMed and Cochrane databases were last conducted in August 2017 and yielded 300 unique citations. Of these, 36 met the inclusion criteria and were rated according to the strength of evidence; 6 articles were rated level I, 11 articles were rated level II, and 19 articles were rated level III. RESULTS: Reported outcomes were change in angle width, effect on intraocular pressure (IOP) control, disease progression, and complications...
February 23, 2018: Ophthalmology
https://www.readbyqxmd.com/read/29419553/malpractice-litigation-in-cornea-and-refractive-surgery-a-review-of-the-westlaw-database
#18
Stephanie B Engelhard, Christopher T Shah, Austin J Sim, Ashvini K Reddy
PURPOSE: To report and analyze the causes and outcomes of malpractice litigation in cornea and refractive surgery. METHODS: The WestLaw database was reviewed for all malpractice litigation related to ophthalmology in the United States between 1930 and 2014. Search terms included ophthalmology or ophthalmologist and malpractice anywhere in the retrieved results. All cases involving cornea and refractive surgery were included in this analysis, and results were compared with ophthalmology as a whole...
May 2018: Cornea
https://www.readbyqxmd.com/read/29364259/second-harmonic-generation-signals-in-rabbit-sclera-as-a-tool-for-evaluation-of-therapeutic-tissue-cross-linking-txl-for-myopia
#19
Mariya Zyablitskaya, E Laura Munteanu, Takayuki Nagasaki, David C Paik
Methods to strengthen tissue by introducing chemical bonds (non-enzymatic cross-linking) into structural proteins (fibrillar collagens) for therapy include photochemical cross-linking and tissue cross-linking (TXL) methods. Such methods for inducing mechanical tissue property changes are being employed to the cornea in corneal thinning (mechanically weakened) disorders such as keratoconus as well as the sclera in progressive myopia, where thinning and weakening of the posterior sclera occurs and likely contributes to axial elongation...
January 6, 2018: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29359085/volumetric-fluorescence-retinal-imaging-in-vivo-over-a-30-degree-field-of-view-by-oblique-scanning-laser-ophthalmoscopy-oslo
#20
Lei Zhang, Weiye Song, Di Shao, Sui Zhang, Manishi Desai, Steven Ness, Sayon Roy, Ji Yi
While fluorescent contrast is widely used in ophthalmology, three-dimensional (3D) fluorescence retinal imaging over a large field of view (FOV) has been challenging. In this paper, we describe a novel oblique scanning laser ophthalmoscopy (oSLO) technique that provides 3D volumetric fluorescence retinal imaging with only one raster scan. The technique utilizes scanned oblique illumination and angled detection to obtain fluorescent cross-sectional images, analogous to optical coherence tomography (OCT) line scans (or B-scans)...
January 1, 2018: Biomedical Optics Express
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