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https://www.readbyqxmd.com/read/28340121/atrioventricular-nodal-echoes-over-a-wide-echo-window-as-a-therapeutic-end-point-for-the-catheter-guided-radiofrequency-ablation-of-atrioventricular-nodal-reentrant-tachycardia-a-prospective-study
#1
Mohammad Hossein Nikoo, Armin Attar, Mohammad Pourmontaseri, Mohammad Vahid Jorat, Mohammad Kafi
Aims: In previous retrospective studies, it was shown that the presence of residual single atrioventricular node (AVN) echoes with an echo zone longer than 30 ms may increase the rate of recurrence after radiofrequency ablation (RFA) of slow pathway in patients with AVN reentrant tachycardia (AVNRT). Based on that, some centres perform additional RFA in these patients. However, this opinion has never been tested prospectively and many centres do not perform re-ablation in these patients...
March 15, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28337285/preclinical-and-clinical-evaluation-of-the-liver-tumor-irreversible-electroporation-by-magnetic-resonance-imaging
#2
Matteo Figini, Xifu Wang, Tianchu Lyu, Zhanliang Su, Daniele Procissi, Vahid Yaghmai, Andrew C Larson, Zhuoli Zhang
Irreversible electroporation (IRE) is a relatively new technique for tumor ablation. It has shown promising results in difficult cases where surgery is not recommended and delicate anatomic structures are present near or within the tumor. Currently, liver cancer is one of the most common targets for IRE treatment. Pre-operative and post-operative imaging has a key role in IRE procedures and research studies. Although ultrasound is usually the first choice, especially for intra-operative guidance, magnetic resonance imaging (MRI) plays an important role in the visualization and characterization of tumor before and after IRE in clinical and preclinical studies...
2017: American Journal of Translational Research
https://www.readbyqxmd.com/read/28337056/normative-values-and-contralateral-comparison-of-anterior-chamber-parameters-measured-by-pentacam-and-its-correlation-with-corneal-biomechanical-factors
#3
Mohammad Reza Sedaghat, Vahid Mohammad Zadeh, Kaveh Fadakar, Sakineh Kadivar, Mojtaba Abrishami
PURPOSE: To evaluate the normative values of anterior chamber parameters measured by Pentacam and corneal hysteresis (CH) and corneal resistance factor (CRF) measured by Ocular Response Analyzer (ORA) and their relationship. METHODS: In an observational cross-sectional study, patients aged 18-35 years were included. Exclusion criteria were history of any intraocular or corneal disease, anomaly or surgery; hyperopic spherical refraction more than +3, and myopic spherical refraction less than -5...
January 2017: Saudi Journal of Ophthalmology: Official Journal of the Saudi Ophthalmological Society
https://www.readbyqxmd.com/read/28335389/characteristics%C3%A2-and%C3%A2-lethality%C3%A2-of%C3%A2-a%C3%A2-novel%C3%A2-recombinant%C3%A2-dermonecrotic%C3%A2-venom%C3%A2-phospholipase%C3%A2-d%C3%A2-from%C3%A2-hemiscorpius%C3%A2-lepturus
#4
Elham Torabi, Mahdi Behdani, Mohammad Hosseininejad Chafi, Reza Moazzami, Jean-Marc Sabatier, Vahid Khalaj, Delavar Shahbazzadeh, Kamran Pooshang Bagheri
Hemoscorpius lepturus is the most medically important scorpion in Iran. The clinical signs of H. lepturus envenomation are remarkably similar to those reported for brown spiders, including dermonecrosis, hematuria, renal failure and even death. The lethality and toxicity of brown spiders' venom have been attributed to its phospholipase D activity. This study aims to identify a phospholipase D with possible lethality and dermonecrotic activity in H. lepturus venom. In this study, a cDNA library of the venom glands was generated by Illumina RNA sequencing...
March 13, 2017: Toxins
https://www.readbyqxmd.com/read/28331560/introducing-crucial-protein-panel-of-gastric-adenocarcinoma-disease
#5
Mostafa Rezaei-Tavirani, Majid Rezaei-Tavirani, Vahid Mansouri, Seyed Mohammad Mahdavi, Reza Valizadeh, Mohammad Rostami-Nejad, Mohammad Reza Zali
AIM: Since interactome analysis of diseases can provide candidate biomarker panel related to the diseases, in this research, protein-protein interaction (PPI) network analysis is used to introduce the involved crucial proteins in Gastric adenocarcinoma (GA). BACKGROUND: Gastric adenocarcinoma (GA) is the most common type of stomach cancer. There is no efficient diagnostic molecular method for GA. METHOD: Applying Cytoscape software 3.4.0 and String Database, the PPI network was constructed for 200 genes...
2017: Gastroenterology and Hepatology From Bed to Bench
https://www.readbyqxmd.com/read/28328317/antiproliferative-and-apoptotic-effects-of-novel-anti-ror1-single-chain-antibodies-in-hematological-malignancies
#6
Leili Aghebati-Maleki, Vahid Younesi, Behzad Baradaran, Jalal Abdolalizadeh, Morteza Motallebnezhad, Hamid Nickho, Dariush Shanehbandi, Jafar Majidi, Mehdi Yousefi
Receptor tyrosine kinase-like orphan receptor (ROR) proteins are a conserved family of tyrosine kinase receptors that function in developmental processes including cell survival, differentiation, cell migration, cell communication, cell polarity, proliferation, metabolism, and angiogenesis. ROR1 has recently been shown to be expressed in various types of cancer cells but not normal cells. Pharmacokinetics and pharmacodynamics of single-chain Fragment variable (scFv) antibodies provide potential therapeutic advantages over whole antibody molecules...
April 2017: SLAS Discov
https://www.readbyqxmd.com/read/28326892/clinical-and-histomorphometric-assessment-of-lateral-alveolar-ridge-augmentation-using-a-corticocancellous-freeze-dried-allograft-bone-block
#7
Roya Shariatmadar Ahmadi, Ferena Sayar, Vahid Rakhshan, Babak Iranpour, Jahanfar Jahanbani, Ahmad Toumaj, Nasrin Akhoondi
Horizontal ridge augmentation with allografts has attracted notable attention because of its proper success rate and the lack of disadvantages of autografts. Corticocancellous block allografts have not been adequately studied on humans. Therefore, this study evaluated clinically and histomorphometrically the increase in ridge with after horizontal ridge augmentation using corticocancellous block allografts, and the implant success after 12 to 18 months post-implantation. In 10 implant patients (3 women, 7 men, 45 years old on average), defective maxillary alveolar ridges were horizontally augmented using freeze-dried bone allograft blocks...
March 22, 2017: Journal of Oral Implantology
https://www.readbyqxmd.com/read/28325142/calcium-phosphate-nanoparticles-cytocompatibility-versus-cytotoxicity-a-serendipitous-paradox
#8
Milad Pourbaghi Masouleh, Vahid Hosseini, Masoud Pourhaghgouy, Martin K Bakht
Due to efficacious characteristics of calcium phosphate nanoparticles (CPNs), they have numerously been employed in nanomedicine, particularly as carrier for therapeutic and diagnostic agents, and also in tissue engineering. Although calcium phosphate minerals are noted for their cytocompatibility, there are outstanding findings from various studies that question whether they are still compatible with cells in nanoscale ranges or not and it leads to the controversial issue of CPNs cytocompatibility versus cytotoxicity...
March 21, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/28324942/quantitative-analysis-of-histological-tissue-image-based-on-cytological-profiles-and-spatial-statistics
#9
Young Hwan Chang, Guillaume Thibault, Vahid Azimi, Brett Johnson, Danielle Jorgens, Jason Link, Adam Margolin, Joe W Gray
The cellular heterogeneity and complex tissue architecture of most tumor samples is a major obstacle in image analysis on standard hematoxylin and eosin-stained (H&E) tissue sections. A mixture of cancer and normal cells complicates the interpretation of their cytological profiles. Furthermore, spatial arrangement and architectural organization of cells are generally not reflected in cellular characteristics analysis. To address these challenges, first we describe an automatic nuclei segmentation of H&E tissue sections...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28317723/multi-spectroscopic-and-molecular-modeling-studies-of-bovine-serum-albumin-interaction-with-sodium-acetate-food-additive
#10
Hossein Mohammadzadeh-Aghdash, Jafar Ezzati Nazhad Dolatabadi, Parvin Dehghan, Vahid Panahi-Azar, Abolfazl Barzegar
Sodium acetate (SA) has been used as a highly effective protectant in food industry and the possible effect of this additive on the binding to albumin should be taken into consideration. Therefore, for the first time, the mechanism of SA interaction with bovine serum albumin (BSA) has been investigated by multi-spectroscopic and molecular modeling methods under physiological conditions. Stern-Volmer fluorescence quenching analysis showed an increase in the fluorescence intensity of BSA upon increasing the amounts of SA...
August 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28316420/lb-broth-lyophilized-rabbit-serum-llr-as-a-new-and-suitable-culture-medium-for-cultivation-of-promastigotes-of-leishmania-major
#11
Vahid Nasiri, Abdolhossein Dalimi, Fatemeh Ghaffarifar
Fetal calf serum is the major part and the most expensive ingredient of the Leishmania culture media. Here, the efficacy of the LB broth-lyophilized Rabbit serum medium (LLR) was evaluated in cultivation of Leishmaniamajor. Conventional Luria-Bertani (LB) broth medium was prepared and autoclaved for 15 min at 121 °C and then lyophilized Rabbit serum was added at the 1, 2.5, 5 and 10 % final concentrations. The efficacy of medium was evaluated by assessing the growth ability and replication pattern of the promastigotes of L...
March 2017: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
https://www.readbyqxmd.com/read/28314537/prevalence-of-diabetes-type-2-in-older-adults-findings-from-a-large-population-based-survey-in-tehran-iran-urban-heart-2
#12
Vahid Rashedi, Mohsen Asadi-Lari, Ahmad Delbari, Reza Fadayevatan, Vahidreza Borhaninejad, Mahshid Foroughan
AIMS: Diabetes is a common problem in older adults, as they increasingly comprise a larger proportion of patients newly diagnosed with diabetes. The evidence on the prevalence and distribution of type 2 diabetes (DT2) and its related factors among older adults in Iran is sparse. The aim of the present study was to determine the prevalence of DT2 among Iranian older adults aged ≥60years. MATERIALS AND METHODS: The study was part of a comprehensive survey (Urban HEART-2) which was a large population-based cross-sectional study...
March 8, 2017: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/28299300/the-health-seeking-behaviors-and-perceptions-of-iranian-patient-with-osteoarthritis-about-pain-management-a-qualitative-study
#13
Vahid Zamanzadeh, Fazlollah Ahmadi, Marjaneh Foolady, Mozhgan Behshid, Alireza Irajpoor
Introduction: Pain is the main reason for patients with osteoarthritis (OA) to visit health clinics. Health seeking behaviors indicate unmet patient needs and lack of understanding of OA pain patterns. This study aimed to describe the experiences of Iranian patients with OA and explore their health seeking behaviors and perceptions on pain management related to osteoarthritis. Methods: Using a qualitative approach, data was collected by interviewing 19 patients, 2 family members, and 5 health care providers from the in-patient and out-patient clinics, and physicians' offices...
March 2017: Journal of Caring Sciences
https://www.readbyqxmd.com/read/28299031/continuity-of-care-evaluation-the-view-of-patients-and-professionals-about-urban-family-physician-program
#14
Vahid Kohpeima Jahromi, Mohammad Hossein Mehrolhassani, Reza Dehnavieh, Hosein Saberi Anari
BACKGROUND: A responsibility of the family physician (FP) and one of the four aspects of the delivery of primary care services is continuity of care (COC). This study aimed to determine the COC of health care in urban health centers. METHODS: Between September 2015 and March 2016, we conducted a cross-sectional study using Primary Care Evaluation Tool questionnaires with multistage stratified cluster sample of FPs (n = 141) and patients (n = 710) in two provinces in Iran, Fars and Mazandaran...
2017: International Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28295815/elucidating-the-interaction-of-clofazimine-with-bovine-liver-catalase-a-comprehensive-spectroscopic-and-molecular-docking-approach
#15
Masihuz Zaman, Saima Nusrat, Syed Mohammad Zakariya, Mohsin Vahid Khan, Mohammad Rehan Ajmal, Rizwan Hasan Khan
Nowadays, understanding of interface between protein and drugs has become an active research area of interest. These types of interactions provide structural guidelines in drug design with greater clinical efficacy. Thus, structural changes in catalase induced by clofazimine were monitored by various biophysical techniques including UV-visible spectrometer, fluorescence spectroscopy, circular dichroism, and dynamic light scattering techniques. Increase in absorption spectra (UV-visible spectrum) confers the complex formation between drug and protein...
March 14, 2017: Journal of Molecular Recognition: JMR
https://www.readbyqxmd.com/read/28294401/endothelial-progenitor-cell-mobilization-in-preterm-infants-with-sepsis-is-associated-with-improved-survival
#16
Vahid Siavashi, Simin Asadian, Masoud Taheri-Asl, Samaneh Keshavarz, Mohamad Zamani-Ahmadmahmudi, Seyed Mahdi Nassiri
Microvascular dysfunction plays a key role in the pathology of sepsis, leading to multi-organ failure and death. Circulating endothelial progenitor cells (cEPCs) are critically involved in the maintenance of the vascular homeostasis in both physiological and pathological contexts. In this study, concentration of cEPCs in preterm infants with sepsis was determined to recognize whether the EPC mobilization would affect the clinical outcome of infantile sepsis. 133 preterm infants (81 with sepsis and 52 without sepsis) were enrolled in this study...
March 10, 2017: Journal of Cellular Biochemistry
https://www.readbyqxmd.com/read/28293427/indicator-bacteria-community-in-seawater-and-coastal-sediment-the-persian-gulf-as-a-case
#17
Vahid Noroozi Karbasdehi, Sina Dobaradaran, Iraj Nabipour, Afshin Ostovar, Hossein Arfaeinia, Amir Vazirizadeh, Roghayeh Mirahmadi, Mozhgan Keshtkar, Fatemeh Faraji Ghasemi, Farzaneh Khalifei
BACKGROUND: The aim of present work was to assess the concentration levels as well as vertical distribution of indicator bacteria including total coliform, fecal coliform, Pseudomonas aeruginosa, and Heterotrophic Plate Count (HPC) in the marine environment (seawater and coastal sediments) and evaluate the correlation between indicator bacteria and some physicochemical parameters of surface sediments as well as seawaters. METHODS: A total number of 48 seawater and sediment samples were taken from 8 stations (each site 6 times with an interval time of 2 weeks) between June and September 2014...
2017: Journal of Environmental Health Science & Engineering
https://www.readbyqxmd.com/read/28289951/distribution-of-the-anterior-posterior-and-total-corneal-astigmatism-in-healthy-eyes
#18
Sepehr Feizi, Mohammad Naderan, Vahid Ownagh, Fatemeh Sadeghpour
PURPOSE: To evaluate the magnitude and axis orientation of the anterior, posterior, and total corneal astigmatism in normal healthy eyes of an Iranian population. METHODS: In a prospective cross-sectional study, ophthalmic and anterior segment parameters of 153 healthy eyes of 153 subjects were evaluated by Galilei dual Scheimpflug analyzer. The magnitude and axis orientation [with-the-rule (WTR), against-the-rule (ATR), and oblique] of the anterior, posterior, and total corneal astigmatism measurements (ACA, PCA, and TCA) were compared according to the age, sex, and other ophthalmic parameters...
March 13, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28288135/targeting-lyn-regulates-snail-family-shuttling-and-inhibits-metastasis
#19
D Thaper, S Vahid, K M Nip, I Moskalev, X Shan, S Frees, M E Roberts, K Ketola, K W Harder, C Gregory-Evans, J L Bishop, A Zoubeidi
The acquisition of an invasive phenotype by epithelial cells occurs through a loss of cellular adhesion and polarity, heralding a multistep process that leads to metastatic dissemination. Since its characterization in 1995, epithelial-mesenchymal transition (EMT) has been closely linked to the metastatic process. As a defining aspect of EMT, loss of cell adhesion through downregulation of E-cadherin is carried out by several transcriptional repressors; key among them the SNAI family of transcription factors...
March 13, 2017: Oncogene
https://www.readbyqxmd.com/read/28286609/conjugated-estrogen-in-late-onset-hemorrhagic-cystitis-associated-with-hematopoietic-stem-cell-transplantation
#20
Seyed Asadollah Mousavi, Vahid Moazed, Niayesh Mohebbi, Molouk Hadjibabaie, Kamran Alimoghaddam, Babak Bahar, Mohammad Jahani, Ardeshir Ghavamzadeh
Background: Hemorrhagic cystitis (HC) is one of the most challenging complications in hematopoietic stem cell transplantation (HSCT). Estrogen is one of the suggested treatments for controlling this problem. Subjects and Methods: We performed a randomized case-control study to evaluate the efficacy of oral conjugated estrogen on HC management in 56 HSCT patients. Patients were randomly assigned to the drug group (received 6.25 mg conjugated estrogen oral tablets in a daily single dose during hematuria period) or control group...
January 1, 2017: International Journal of Hematology-oncology and Stem Cell Research
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