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https://www.readbyqxmd.com/read/29448215/synthesis-of-dual-temperature-and-ph-responsive-yolk-shell-nanoparticles-by-conventional-etching-and-new-deswelling-approaches-dox-release-behavior
#1
Goolia Nikravan, Vahid Haddadi-Asl, Mehdi Salami-Kalajahi
Dual stimuli-responsive yolk-shell nanoparticles with cross-linked poly(acrylic acid) (PAA) pH-responsive core and cross-linked poly(2-hydroxyethyl methacrylate) (PHEMA) temperature-responsive shell were synthesized via two different methods In the first method, silica encapsulated PAA (PAA@SiO 2 ) was used as seed in distillation precipitation polymerization (DPP) of HEMA to yield PAA@SiO 2 @PHEMA from which silica layer was etched by HF solution to produce yolk-shell PAA@air@PHEMA nanoparticles. In the second method, swollen PAA nanoparticles at pH = 10 were used as seeds in emulsion polymerization of HEMA to yield core-shell PAA@PHEMA nanoparticles...
February 9, 2018: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/29440813/anxiety-and-depression-a-cross-sectional-survey-among-parents-of-children-with-cancer
#2
Azad Rahmani, Arman Azadi, Vahid Pakpour, Safieh Faghani, Ebrahim Ali Afsari
Context: Parents of children with cancer are experiencing high levels of psychological distress. Elevated levels of depression and anxiety following the disclosure of diagnosis affect many aspects of parents' health. Aims: The aim of this study was to assess anxiety and depression of parents of Iranian children with cancer. Settings and Design: This descriptive-correlational study was undertaken among 148 parents of children with cancer admitted to a pediatric hospital affiliated to Tabriz University of Medical Sciences, Tabriz/Iran...
January 2018: Indian Journal of Palliative Care
https://www.readbyqxmd.com/read/29436790/cromakalim-a-potassium-channel-opener-ameliorates-the-organophosphate-and-carbamate-induced-seizure-in-mice
#3
Sattar Ostadhadi, Abouzar Moradi, Samira Zolfaghari, Vahid Nikoui, Ahmad Reza Dehpour
Organophosphates (OPs) and carbamates are acetylcholine esterase inhibitors (AChEIs), which can cause seizure and lethality. Anticonvulsant properties of potassium channel openers including cromakalim have been determined in previous studies. In the present experiment, the possible effect of cromakalim on the convulsion and death induced by OPs and carbamates was studied in mice. Dichlorvos (an OP, 50 mg/kg) and physostigmine (a carbamate, 2 mg/kg) were used to induce seizure in animals. Cromakalim at doses of 0...
January 2018: Acta Medica Iranica
https://www.readbyqxmd.com/read/29435632/chemometrics-assisted-microfluidic-paper-based-analytical-device-for-the-determination-of-uric-acid-by-silver-nanoparticle-plasmon-resonance
#4
Vahid Hamedpour, Geert J Postma, Edwin van den Heuvel, Jeroen J Jansen, Koji Suzuki, Daniel Citterio
This manuscript reports on the application of chemometric methods for the development of an optimized microfluidic paper-based analytical device (μPAD). As an example, we applied chemometric methods for both device optimization and data processing of results of a colorimetric uric acid assay. Box-Behnken designs (BBD) were utilized for the optimization of the device geometry and the amount of thermal inkjet-deposited assay reagents, which affect the assay performance. Measurement outliers were detected in real time by partial least squares discriminant analysis (PLS-DA) of scanned images...
February 12, 2018: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/29432200/reliability-and-validity-of-lumbar-disc-height-quantification-methods-using-magnetic-resonance-images
#5
Vahid Abdollah, Eric C Parent, Michele C Battié
Disc height has been a focus of research on disc degeneration and low back pain (LBP). However, choosing an appropriate method to quantify disc height remains controversial. The aim of the present study was to determine the reliability and construct validity of disc height quantification methods. Repeated semi-automatic measurements of L4-5 and L5-S1 discs were obtained from 43 T2-weighted mid-sagittal 3T magnetic resonance (MR) images of 22 subjects with LBP (43±13 years), blinded to prior measurements. Heights were calculated with area-based methods (using 60%, 80% and 100% of the disc width), and point-based methods (Hurxthal's, Dabbs' and combining the two)...
February 13, 2018: Biomedizinische Technik. Biomedical Engineering
https://www.readbyqxmd.com/read/29429651/ultrasound-assisted-synthesis-of-amide-functionalized-metal-organic-framework-for-nitroaromatic-sensing
#6
Maniya Gharib, Vahid Safarifard, Ali Morsali
Nano plates of zinc(II) based metal-organic framework (MOF) were prepared via ultrasonic method without any surfactants at room temperature and atmospheric pressure. Control of particle size and morphology was enhanced in this synthesis method. Nano plates of an interpenetrated amide-functionalized metal-organic framework, [Zn2(oba)2(bpfb)]·(DMF)5, TMU-23, (H2oba = 4,4'-oxybis(benzoic acid); bpfb = N,N'-bis-(4-pyridylformamide)-1,4-benzenediamine, DMF = N,N-dimethyl formamide), was synthesized under ultrasound irradiation in different concentrations of initial precursor...
April 2018: Ultrasonics Sonochemistry
https://www.readbyqxmd.com/read/29426686/reinforcing-the-importance-and-feasibility-of-implementing-a-low-dose-protocol-for-ct-guided-biopsies
#7
Eric J Keller, Robert J Lewandowski, Lee Goodwin, Vahid Yaghmai, Albert Nemcek, James C Carr, Jeremy D Collins
RATIONALE AND OBJECTIVES: This study sought to more definitely illustrate the impact and feasibility of implementing a low-dose protocol for computed tomography (CT)-guided biopsies using size-specific dose estimates and multivariate analyses. MATERIALS AND METHODS: Fifty consecutive CT-guided lung and extrapulmonary biopsies were reviewed before and after implementation of a low-dose protocol (200 patients total, mean age 61 ± 15 years, 128 women). Analyses of variance with Bonferroni correction were used to compare standard and low-dose protocols in terms of patient demographics, physician experience, target lesion size, total dose-length product, total acquisitions, size-specific dose estimate, signal-to-noise ratio, contrast-to-noise ratio, and lesion conspicuity ratings...
February 6, 2018: Academic Radiology
https://www.readbyqxmd.com/read/29423720/association-of-interferon-regulatory-factor-5-irf5-gene-polymorphisms-with-juvenile-idiopathic-arthritis
#8
Samira Esmaeili Reykande, Arezou Rezaei, Maryam Sadr, Mahsima Shabani, Farnaz Najmi Varzaneh, Vahid Ziaee, Nima Rezaei
Interferon regulatory factor 5 (IRF5) is a member of IRF family which induce signaling pathways and are involved in modulation of cell growth, differentiation, apoptosis, and immune system activity. Juvenile idiopathic arthritis (JIA) is an auto-inflammatory syndrome where the inflammatory markers are believed to play a fundamental role in its pathogenesis. In this study, we aimed to assess the association of IRF5 gene polymorphisms with susceptibility of JIA in Iranian population. Three IRF5 single-nucleotide polymorphisms (rs10954213 A/G, rs2004640 G/T, and rs3807306 G/T) were genotyped using TaqMan assays in 55 patients with JIA and 63 matched healthy individuals...
February 8, 2018: Clinical Rheumatology
https://www.readbyqxmd.com/read/29423547/bpdai-and-absis-correlate-with-serum-anti-bp180-nc16a-igg-but-not-with-anti-bp230-igg-in-patients-with-bullous-pemphigoid
#9
Maryam Daneshpazhooh, Maryam Ghiasi, Vahideh Lajevardi, Nafise Nasiri, Kamran Balighi, Amir Teimourpour, Hasan Khosravi, Vahide Saeidi, Hamidreza Mahmoudi, Cheyda Chams-Davatchi
Bullous pemphigoid (BP) is an autoimmune bullous disease characterized by autoantibody production against BP180 and BP230. Two scoring systems have been validated for BP including: Bullous Pemphigoid Disease Area Index (BPDAI) and Autoimmune Bullous Skin Disorder Intensity Score (ABSIS). In this study, we investigated correlations between both scoring systems and either anti-BP180 NC16A or anti-BP230 values. BPDAI and ABSIS were used to measure disease activity in 95 BP patients at Razi Hospital in Tehran, Iran...
February 8, 2018: Archives of Dermatological Research
https://www.readbyqxmd.com/read/29417079/prescription-pattern-analysis-of-nonsteroidal-anti-inflammatory-drugs-in-the-northeastern-iranian-population
#10
Majid Zeinali, Jamshid Tabeshpour, Seyed Vahid Maziar, Zhila Taherzadeh, Mohammad Reza Zirak, Danielle Sent, Kamal Razavi Azarkhiavi, Saeid Eslami
Objective: Inappropriate nonsteroidal anti-inflammatory drugs (NSAIDs) therapy is a common cause of actual and potential adverse effects, such as bleeding and gastrointestinal ulceration, which exacerbates the patient's medical condition and might even be life threatening. We aimed to evaluate and analyze the prescription pattern of NSAIDs in Northeastern Iranian population and also provide suggestions for a more rational prescription behavior for such drugs. Methods: In this cross-sectional retrospective study, pattern of 1-year prescriptions was inspected based on 9...
October 2017: Journal of Research in Pharmacy Practice
https://www.readbyqxmd.com/read/29416838/investigating-the-role-of-interpersonal-sensitivity-anger-and-perfectionism-in-social-anxiety
#11
Youkhabeh Mohammadian, Behzad Mahaki, Mahmoud Dehghani, Mohammadkazem Atef Vahid, Fahimeh Fathali Lavasani
Background: The investigation of personality characteristics and emotional experiences of the people suffering from anxiety disorders is one of the most important issues which are considered by researchers and clinicians. Perfectionism, sensitivity to interpersonal rejection, and anger are personality traits related to social anxiety. In social anxiety disorder, it has also been focused on anger as a personality characteristic and as an emotional condition. The main purpose of this work is to investigate the role of these variables in predicting social anxiety among a nonclinical group of Iranian students...
2018: International Journal of Preventive Medicine
https://www.readbyqxmd.com/read/29416213/the-role-of-doppler-imaging-in-the-assessment-of-right-ventricular-function-a-case-control-study-of-acute-inferior-wall-infarction
#12
Mojdeh Dabirian, Mohsen Aarabi, Maryam Nabati, Babak Bagheri, Shideh Nikoohemat, Vahid Mokhberi, Aliasghar Farsavian, Hadi Darvishi-Khezri
Background: Right ventricular infarction (RVI) develops in 30-50% of patients with inferior wall infarction (IWI). The rates of mortality, morbidity, and complications in these patients are greater than in the patients without RVI. We compared the tissue Doppler imaging (TDI) indices between a group of patients with IWI and RVI, with a similar group of patients who had IWI alone to investigate the application of TDI indices in the evaluation and detection of right ventricular function...
February 2018: Medical Archives
https://www.readbyqxmd.com/read/29414833/increased-proportion-of-tc17-and-th17-cells-and-their-significant-reduction-after-thymectomy-may-be-related-to-disease-progression-in-myasthenia-gravis
#13
Mina Hosseini, Behrouz Robat-Jazi, Vahid Shaygannejad, Shahriar Naffisi, Omid Mirmossayeb, Abbas Rezaei, Marjan Mansourian, Nafiseh Esmaeil
OBJECTIVE: Myasthenia gravis (MG) is an autoimmune disease mediated by autoantibodies against the neuromuscular junction. The thymus has an important role in the pathogenesis of MG because most patients have thymic pathology, and thymectomy (TE) can reduce the severity of the disease. METHODS: In this study, the frequency of Th17 and Tc17 cells was studied in 12 MG patients (pre-TE and 6 months post-TE) and in 12 healthy controls (HC). RESULTS: The frequency of Tc17 cells in the pre-TE patients was significantly higher than in the HC (p < 0...
February 8, 2018: Neuroimmunomodulation
https://www.readbyqxmd.com/read/29412127/investigating-the-association-between-mir-608-rs4919510-and-mir-149-rs2292832-with-colorectal-cancer-in-iranian-population
#14
Reza Ranjbar, Vahid Chaleshi, Hamid Asadzadeh Aghdaei, Saeid Morovvati
BACKGROUND: Single nucleotide polymorphisms (SNPs) in microRNA (miRNA) networks may serve as diagnostic and prognostic biomarkers of a variety of diseases such as cancer. Some studies have been performed to examine associations between miR-149 and miR-608 polymorphisms and susceptibility to colorectal cancer, but the results remain controversial and race-dependent. OBJECTIVE: The aim of our study was to investigate the association of miR-608 (rs4919510) and miR-149 (rs2292832) with colorectal cancer and its clinical features in a sample of Iranian population...
February 6, 2018: MicroRNA
https://www.readbyqxmd.com/read/29412016/reactions-to-both-nonionic-iodinated-and-gadolinium-based-contrast-media-incidence-and-clinical-characteristics
#15
Faezeh Sodagari, Amirhossein Mozaffary, Cecil G Wood, Brenda Schmitz, Frank H Miller, Vahid Yaghmai
OBJECTIVE: The objective or our study was to assess the incidence rate and clinical characteristics of allergiclike reactions in patients who received both nonionic iodinated contrast medium (ICM) and gadolinium-based contrast medium (GBCM). MATERIALS AND METHODS: Acute allergiclike reactions in patients who received both ICM and GBCM to nonionic ICM or GBCM injections during a 5-year period were analyzed. Allergy preparation was not administered when patients received a different type of contrast material...
February 7, 2018: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/29407848/leptospirosis-in-caspian-sea-littoral-gilan-province-iran
#16
Vahid Garshasbi, Saied Reza Naddaf, Zohreh Aghighi, Nayerreh Hassan, Mohammad Pooya, Ehsan Mostafavi
In Iran, leptospirosis is endemic to Caspian Sea littoral. The disease appears as a seasonal infection mostly affecting people in rural areas involved in farming. We investigated the prevalence of this infection among suspected patients in Gilan Province by an indirect immunofluorescent assay (IFA), and two PCR protocols, a nested-PCR and a real-time PCR (qPCR), targeting rrs and lipL32 genes, respectively. We also identified the common Leptospira species by sequencing a partial sequence of rrs gene. Out of the 128 sera examined by IFA, 25...
January 29, 2018: Acta Tropica
https://www.readbyqxmd.com/read/29403593/upcoming-methods-and-specifications-of-continuous-intraocular-pressure-monitoring-systems-for-glaucoma
#17
Amir Molaei, Vahid Karamzadeh, Sare Safi, Hamed Esfandiari, Javad Dargahi, Mohammad Azam Khosravi
Glaucoma is the leading cause of irreversible blindness and vision loss in the world. Although intraocular pressure (IOP) is no longer considered the only risk factor for glaucoma, it is still the most important one. In most cases, high IOP is secondary to trabecular meshwork dysfunction. High IOP leads to compaction of the lamina cribrosa and subsequent damage to retinal ganglion cell axons. Damage to the optic nerve head is evident on funduscopy as posterior bowing of the lamina cribrosa and increased cupping...
January 2018: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/29399554/sirna-mediated-silencing-of-cip2a-enhances-docetaxel-activity-against-pc-3-prostate-cancer-cells
#18
Saiedeh Razi Soofiyani, Akbar Mohammad Hoseini, Ali Mohammadi, Vahid Khaze Shahgoli, Behzad Baradaran, Mohammad Saeid Hejazi
Purpose: Cancerous inhibitor of protein phosphatase 2A (CIP2A) is an identified human oncoprotein which modulates malignant cell growth. It is overexpressed in human prostate cancer and in most of the human malignancies. The aim of this study was to investigate the effects of CIP2A silencing on the sensitivity of PC-3 prostate cancer cells to docetaxel chemotherapy. Methods: PC-3 cells were transfected using CIP2A siRNA. CIP2A mRNA and protein expression were assessed after CIP2A gene silencing using q-RT PCR and Western blotting...
December 2017: Advanced Pharmaceutical Bulletin
https://www.readbyqxmd.com/read/29399337/neuroprotective-effects-of-selegiline-on-rat-neural-stem-cells-treated-with-hydrogen-peroxide
#19
Alireza Abdanipour, Iraj Jafari Anarkooli, Saeed Shokri, Mehrdad Ghorbanlou, Vahid Bayati, Reza Nejatbakhsh
Oxidative stress and reactive oxygen species generation have been implicated in the pathogenesis of several neurological disorders including Parkinson's disease, Alzheimer's disease, amyotrophic lateral sclerosis and multiple sclerosis. In the present study, the neuroprotective effects of selegiline against hydrogen peroxide-induced oxidative stress in hippocampus-derived neural stem cells (NSCs) were evaluated. NSCs isolated from neonatal Wistar rats were pretreated with different doses of selegiline for 48 h and then exposed to 125 µM H2O2 for 30 min...
January 2018: Biomedical Reports
https://www.readbyqxmd.com/read/29397383/facilitating-factors-of-self-care-among-hiv-positive-young-women-in-iran-a-qualitative-study
#20
Fatemeh Oskouie, Farzaneh Kashefi, Forough Rafii, Mohammad Mehdi Gouya, Marzieh Vahid-Dastjerdi
Background Providing care for chronic disease such as HIV is a growing challenge in the world. In order to address the challenges of linkage and care in chronic disease management, we need to identify factors that can influence people to get more involved in self-care. This study was part of an extensive qualitative study conducted in Tehran, Iran in 2016. Methods The data were collected through semi-structured interviews conducted on 25 women with HIV, and were analyzed using grounded theory. Four main themes were identified as facilitating self-care among participants: health system support, clinicians' support, family support and improved life expectancy...
February 5, 2018: International Journal of Adolescent Medicine and Health
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