keyword
MENU ▼
Read by QxMD icon Read
search

VAHID

keyword
https://www.readbyqxmd.com/read/28091772/transient-expression-of-recombinant-tissue-plasminogen-activator-rt-pa-gene-in-cucurbit-plants-using-viral-vector
#1
Vahid Jalali Javaran, Alireza Shafeinia, Mokhtar Jalali Javaran, Esmaeil Ghasemi Gojani, Malihe Mirzaee
OBJECTIVE: To use a transient expression system to express a truncated human tissue plasminogen activator (K2S) gene in cucurbit plants. RESULTS: The recombinant tissue plasminogen activator protein (K2S form) was expressed in active form in cucurbit plants. Its molecular weight was 43 kDa. The plant-derived rt-PA was determined using goat anti-rabbit antibody by western blotting. Among the infected lines, the highest expression of rt-PA was 62 ng/100 mg per leaf tissue as measured by ELISA...
January 16, 2017: Biotechnology Letters
https://www.readbyqxmd.com/read/28090795/isolation-and-characterization-of-anti-c-met-single-chain-fragment-variable-scfv-antibodies
#2
Elmira Safaie Qamsari, Zahra Sharifzadeh, Salman Bagheri, Farhad Riazi-Rad, Vahid Younesi, Mohsen Abolhassani, Sepideh Safaei Ghaderi, Behzad Baradaran, Mohammad Hossein Somi, Mehdi Yousefi
The receptor tyrosine kinase (RTK) Met is the cell surface receptor for hepatocyte growth factor (HGF) involved in invasive growth programs during embryogenesis and tumorgenesis. There is compelling evidence suggesting important roles for c-Met in colorectal cancer proliferation, migration, invasion, angiogenesis, and survival. Hence, a molecular inhibitor of an extracellular domain of c-Met receptor that blocks c-Met-cell surface interactions could be of great thera-peutic importance. In an attempt to develop molecular inhibitors of c-Met, single chain variable fragment (scFv) phage display libraries Tomlinson I + J against a specific synthetic oligopeptide from the extracellular domain of c-Met receptor were screened; selected scFv were then characterized using various immune techniques...
January 16, 2017: Journal of Immunotoxicology
https://www.readbyqxmd.com/read/28088732/apelin-13-protects-rat-primary-cortical-glia-neuron-co-culture-against-pentylenetetrazole-induced-toxicity
#3
Taj Pari Kalantaripour, Saeed Esmaeili-Mahani, Vahid Sheibani, Hamid Najafipour, Majid Asadi-Shekaari M
In spite of recent advances in the treatment of epilepsy, up to 35% of people living with the condition do not respond to accessible anti-epileptic drugs (AEDs) and continue to experience regular, devastating and potentially life-threatening seizures. Neuronal death is a significant feature of epilepsy in humans and experimental models. It has been reported that apelin, an endogenous ligand for the angiotensin-1-like receptor (APJ), has anticonvulsive as well as protective effects in some neurodegenerative situations...
January 12, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28081509/in-silico-prediction-of-toxicity-of-phenols-to-tetrahymena-pyriformis-by-using-genetic-algorithm-and-decision-tree-based-modeling-approach
#4
Fatemeh Abbasitabar, Vahid Zare-Shahabadi
Risk assessment of chemicals is an important issue in environmental protection; however, there is a huge lack of experimental data for a large number of end-points. The experimental determination of toxicity of chemicals involves high costs and time-consuming process. In silico tools such as quantitative structure-toxicity relationship (QSTR) models, which are constructed on the basis of computational molecular descriptors, can predict missing data for toxic end-points for existing or even not yet synthesized chemicals...
January 2, 2017: Chemosphere
https://www.readbyqxmd.com/read/28081500/a-highly-sensitive-quantum-dots-dna-nanobiosensor-based-on-fluorescence-resonance-energy-transfer-for-rapid-detection-of-nanomolar-amounts-of-human-papillomavirus-18
#5
Mojtaba Shamsipur, Vahid Nasirian, Kamran Mansouri, Ali Barati, Asad Veisi-Raygani, Soheila Kashanian
A very sensitive and convenient nanobiosensor based on fluorescence resonance energy transfer (FRET) was developed for the detection of a 22-mer oligonucleotides sequence in Human Papillomavirus 18 virus (HPV18) gene. For this purpose, water-soluble CdTe quantum dots (QDs) were synthesized and, subsequently, amino-modified 11-mer oligonucleotide as one of the two necessary probes was attached to QDs surface to form functional QDs-DNA conjugates. Right after addition of the QDs-DNA and a second Cyanine5 (Cy5)-labeled 11-mer oligonucleotide probe to the DNA target solution, the sandwiched hybrids were formed...
January 3, 2017: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/28078248/origanum-vulgare-leaf-extract-protects-mice-bone-marrow-cells-against-ionizing-radiation
#6
Reza Ghasemnezhad Targhi, Vahid Changizi, Farhang Haddad, Mansour Homayoun, Shokouhozaman Soleymanifard
OBJECTIVE: Ionizing radiation produces free radicals which induce DNA damage and cell death. Origanum vulgare leaf extract (OVLE) is a natural compound and its capability of scavenging free radicals and its antioxidant activity have been demonstrated by many researchers. In this study, using micronucleus assay, radioprotective effect of OVLE against clastogenic and cytotoxic effect of gamma irradiation has been investigated in mice bone marrow cells. MATERIALS AND METHODS: OVLE was injected intraperitoneally to the BALB/c mice 1hr prior to gamma irradiation (3Gy) at the doses of 100 and 200 mg/kg...
November 2016: Avicenna Journal of Phytomedicine
https://www.readbyqxmd.com/read/28076860/efficacy-and-survival-of-systemic-psoriasis-treatments-an-analysis-of-the-swiss-registry-sdntt
#7
Julia-Tatjana Maul, Vahid Djamei, Antonios G A Kolios, Barbara Meier, Justine Czernielewski, Pascal Jungo, Nikhil Yawalkar, Carlo Mainetti, Emmanuel Laffitte, Christina Spehr, Mark Anliker, Markus Streit, Matthias Augustin, Stephan Rustenbach, Curdin Conrad, Jürg Hafner, Wolf-Henning Boehncke, Luca Borradori, Michel Gilliet, Peter Itin, Lars E French, Peter Häusermann, Alexander A Navarini
BACKGROUND: The Swiss psoriasis registry SDNTT (Swiss Dermatology Network for Targeted Therapies) records the long-term safety and effectiveness of systemic treatment regimens for psoriasis. PATIENTS AND METHODS: Patients with moderate to severe psoriasis are included in the SDNTT when treatment with a conventional systemic agent or biologic is initiated that was not previously used by the respective patient. Patients are followed over a 5-year period. Clinical data are obtained every 3-6 months using standardized case report forms...
January 12, 2017: Dermatology: International Journal for Clinical and Investigative Dermatology
https://www.readbyqxmd.com/read/28076759/quantitative-in-situ-tem-nanotensile-testing-of-single-crystal-ni-facilitated-by-a-new-sample-preparation-approach
#8
Vahid Samaeeaghmiyoni, Hosni Idrissi, Jonas Groten, Ruth Schwaiger, Dominique Schryvers
Twin-jet electro-polishing and Focused Ion Beam (FIB) were combined to produce small size Nickel single crystal specimens for quantitative in-situ nanotensile experiments in the transmission electron microscope. The combination of these techniques allows producing samples with nearly defect-free zones in the centre in contrast to conventional FIB-prepared samples. Since TEM investigations can be performed on the electro-polished samples prior to in-situ TEM straining, specimens with desired crystallographic orientation and initial microstructure can be prepared...
December 21, 2016: Micron: the International Research and Review Journal for Microscopy
https://www.readbyqxmd.com/read/28069195/effects-of-high-power-ultrasonic-vibration-on-the-cold-compaction-of-titanium
#9
Vahid Fartashvand, Amir Abdullah, Seyed Ali Sadough Vanini
Titanium has widely been used in chemical and aerospace industries. In order to overcome the drawbacks of cold compaction of titanium, the process was assisted by an ultrasonic vibration system. For this purpose, a uniaxial ultrasonic assisted cold powder compaction system was designed and fabricated. The process variables were powder size, compaction pressure and initial powder compact thickness. Density, friction force, ejection force and spring back of the fabricated samples were measured and studied. The density was observed to improve under the action of ultrasonic vibration...
May 2017: Ultrasonics Sonochemistry
https://www.readbyqxmd.com/read/28068317/cryogenic-optical-localization-provides-3d-protein-structure-data-with-angstrom-resolution
#10
Siegfried Weisenburger, Daniel Boening, Benjamin Schomburg, Karin Giller, Stefan Becker, Christian Griesinger, Vahid Sandoghdar
We introduce Cryogenic Optical Localization in 3D (COLD), a method to localize multiple fluorescent sites within a single small protein with Angstrom resolution. We demonstrate COLD by determining the conformational state of the cytosolic Per-ARNT-Sim domain from the histidine kinase CitA of Geobacillus thermodenitrificans and resolving the four biotin sites of streptavidin. COLD provides quantitative 3D information about small- to medium-sized biomolecules on the Angstrom scale and complements other techniques in structural biology...
January 9, 2017: Nature Methods
https://www.readbyqxmd.com/read/28064113/cognitive-control-dysfunction-in-emotion-dysregulation-and-psychopathology-of-major-depression-md-evidence-from-transcranial-brain-stimulation-of-the-dorsolateral-prefrontal-cortex-dlpfc
#11
Mohammad Ali Salehinejad, Elham Ghanavai, Reza Rostami, Vahid Nejati
BACKGROUND: Previous studies showed that MD is associated with a variety of cognitive deficits and executive dysfunctions which can persist even in remitted states. However, the role of cognitive impairments in MD psychopathology and treatment is not fully understood. This article aims to discuss how executive functions central components (e.g., Working memory and attention) mediate MD psychopathology considering the role of dorsolateral prefrontal cortex (dLPFC) and present findings of a brain stimulation experiment to support this notion...
December 31, 2016: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28063646/solute-transport-at-the-interface-of-cartilage-and-subchondral-bone-plate-effect-of-micro-architecture
#12
Behdad Pouran, Vahid Arbabi, Ronald Law Bleys, P René van Weeren, Amir A Zadpoor, Harrie Weinans
Cross-talk of subchondral bone and articular cartilage could be an important aspect in the etiology of osteoarthritis. Previous research has provided some evidence of transport of small molecules (~370Da) through the calcified cartilage and subchondral bone plate in murine osteoarthritis models. The current study, for the first time, uses a neutral diffusing computed tomography (CT) contrast agent (iodixanol, ~1550Da) to study the permeability of the osteochondral interface in equine and human samples. Sequential CT monitoring of diffusion after injecting a finite amount of contrast agent solution onto the cartilage surface using a micro-CT showed penetration of the contrast molecules across the cartilage-bone interface...
December 29, 2016: Journal of Biomechanics
https://www.readbyqxmd.com/read/28059272/graphene-based-side-polished-optical-fiber-amplifier
#13
Mohammad Karimi, Vahid Ahmadi, Masoud Ghezelsefloo
We demonstrate a novel design for optical fiber amplifiers, utilizing side-polished fibers with a single-layer graphene overlay as the active medium and carrier injection in the graphene layer to provide the required inversion. We study the effects of an electrically induced graphene p-i-n heterojunction in the forward bias regime on optical modes of side-polished fibers and show that gain values of 0.51, 1.81, and 1.79 dB/cm for wavelengths 1064, 1330, and 1550 nm can be obtained for single-mode side-polished fibers...
December 20, 2016: Applied Optics
https://www.readbyqxmd.com/read/28054211/management-of-sulcus-fixated-single-piece-intraocular-lens-induced-pigmentary-glaucoma-with-3-piece-iol-exchange
#14
Hossein Mohammad Rabie, Hamed Esfandiari, Mohammad Hassan Rikhtegar, Vahid Hekmat
PURPOSE: To describe our experience with exchanging sulcus-fixated single-piece intraocular lens (IOL) with 3-piece IOLs for management of pigmentary glaucoma. METHOD: In this retrospective study, records of patients who underwent sulcus-fixated single-piece IOL exchanged with 3-piece IOLs were retrieved, and demographic and baseline data of patients, type of IOL, pre- and post-IOL exchange BCVA, IOP, number of anti-glaucoma medications, and optic nerve head examination were documented...
January 4, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28051317/argc-like-digestion-complementary-or-alternative-to-tryptic-digestion
#15
Vahid Golghalyani, Moritz Neupärtl, Ilka Wittig, Ute Bahr, Michael Karas
Enzymatic digestion of complex protein samples is often performed by use of multiple proteases to improve protein identification and characterization. Combining trypsin with ArgC is one option to enhance sequence coverage in bottom-up proteomics. However, the low selectivity of this endoprotease derogates from the benefit of the combination. Our approach here is to mimic ArgC digestion by chemically modifying all lysine residues in proteins so that trypsin can only cleave C-terminal to arginine. Four different amine modifications, dimethylation, acetylation, propionylation, and carbethoxylation, were tested, and the protocols were optimized...
January 11, 2017: Journal of Proteome Research
https://www.readbyqxmd.com/read/28036156/interleukin-4-cytokine-single-nucleotide-polymorphisms-in-kawasaki-disease-a-case-control-study-and-a-review-of-knowledge
#16
Raheleh Assari, Yahya Aghighi, Vahid Ziaee, Maryam Sadr, Arezou Rezaei, Farzaneh Rahmani, Zeinab Sadr, Seyed Reza Raeeskarami, Mohammad Hassan Moradinejad, Nima Rezaei
AIM: Kawasaki disease (KD) is a systemic vasculitis of medium-sized arteries. High levels of interleukin 4 (IL-4) and the dominance of Th2 cytokines seem to be a key feature in the acute phase of KD. In this study, the role of IL-4 and IL-4R gene polymorphisms were investigated in Iranian children with KD. METHODS: Fifty-five patients with KD and 140 healthy subjects as a control group were enrolled in this study. Single nucleotide polymorphisms (SNPs) of IL-4 gene at positions -1098 (rs2243248), -590 (rs2243250) and -33 (rs2070874), as well as IL-4RA gene at position +1902 (rs180275) were assessed in patients and the control group...
December 30, 2016: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/28034693/distance-education-and-diabetes-empowerment-a-single-blind-randomized-control-trial
#17
Vahid Zamanzadeh, Mohammad Zirak, Masomeh Hemmati Maslakpak, Naser Parizad
AIMS: Diabetes is one of the biggest problems in healthcare systems and kills many people every year. Diabetes management is impossible when only utilizing medication. So, patients must be educated to manage their diabetes. This study aims to assess the effect of education by telephone and short message service on empowering patients with type 2 diabetes (primary outcome). MATERIALS AND METHODS: A single-blind randomized controlled trial was conducted in the Urmia diabetes association in Iran...
December 21, 2016: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/28032057/affecting-factors-on-the-performance-of-community-health-workers-in-iran-s-rural-areas-a-review-article
#18
REVIEW
Gholamhossein Salehi Zalani, Mahboubeh Bayat, Azad Shokri, S Elmira Mirbahaeddin, Vahid Rasi, Samira Alirezaei, Fatemeh Manafi
BACKGROUND: This study aimed to use a mixed-method approach to investigate affecting factors on the performance of Community Health Workers (CHW) in Iran's villages. METHODS: This study was conducted during 2014-2015 with a mixed method in three phases of literature review, Delphi technique and developing a rich picture. Overall, in order to finalize the affecting factors and their relationships between qualitative content analysis, Delphi technique, AHP technique and Focus Group Discussion were used, respectively...
November 2016: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/28019667/isolation-identification-and-characterization-of-cancer-stem-cells-a-review
#19
REVIEW
Vahid Bagheri, Mahya Shariat Razavi, Amir Abbas Momtazi, Amirhossein Sahebkar, Mohammad Reza Abbaszadegan, Mehran Gholamin
Cancer stem cells (CSCs) or tumor-initiating cells (TICs) as a small subset of neoplastic cells are able to produce a tumor (tumorigenesis), maintain the population of tumorigenic cells (self-renewal), and generate the heterogeneous cells constructing the entire tumor (pluripotency). The research on stationary and circulating CSCs due to resistance to conventional therapies and inability in complete eradication of cancer is critical for developing novel therapeutic strategies for a more effective reduction in the risk of tumor metastasis and cancer recurrence...
December 26, 2016: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/28012331/multidisciplinary-management-of-a-patient-with-van-der-woude-syndrome-a-case-report
#20
Azita Tehranchi, Hossein Behnia, Nasser Nadjmi, Vahid Reza Yassaee, Zeinab Ravesh, Morteza Mina
INTRODUCTION: Van der Woude syndrome (VWS) is the most frequent form of syndromic cleft lip and palate (SCLP) accounting for 2% of all patients with CLP. CASE PRESENTATION: We describe the orthodontic treatment of a girl diagnosed with VWS referred by her family dentist for her cosmetic concerns. DISCUSSION: Comprehensive orthodontic treatment, secondary bone graft, distraction osteogenesis (for a deficient maxilla), secondary palatoplasty and excision of lower lip pits, as well as orthodontic and prosthetic procedures may provide a satisfactory outcome...
December 6, 2016: International Journal of Surgery Case Reports
keyword
keyword
84228
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"