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Vahid Reza Askari, Vafa Baradaran Rahimi, Parvin Zamani, Narges Fereydouni, Pouria Rahmanian-Devin, Amir Hossein Sahebkar, Hassan Rakhshandeh
BACKGROUND: Peritoneal adhesion is a major complication of surgery that can lead to serious problems such as bowel obstruction, pain, infertility and even mortality. Propolis is a honey bee product with anti-inflammatory and anti-oxidant activities that could potentially protect against adhesive surgical complications. METHODS: Forty 8-weeks-old rats (275 ± 25 g) were divided into five groups: normal group without any surgical procedure, and experimental groups treated with normal saline, 50 mg/kg, 100 mg/kg and 200 mg/kg of propolis...
March 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
Ebrahim Shafaie, Samaneh Saberi, Maryam Esmaeili, Zeynab Karimi, Saeed Najafi, Mohammad Tashakoripoor, Afshin Abdirad, Mahmoud Eshagh Hosseini, Mohammad Ali Mohagheghi, Vahid Khalaj, Marjan Mohammadi
INTRODUCTION: Helicobacter pylori express a large array of antigens, each of which is duly responsible for successful colonization and pathogenesis. Here, we have studied host serum antibody responses to four of its immunodominant antigens in association with the infection status and the resulting clinical outcomes. METHODS: For this purpose, four individual H. pylori proteins (UreB, CagA, Tip-α and HP0175) were produced in recombinant forms. Serum antibody responses of 246 (75 GC and 171 NUD) patients, against the above antigens, were evaluated by multiplex immunoblotting...
April 14, 2018: Microbial Pathogenesis
Razieh Bigdeli, Mohammad Reza Younesi, Erfan Panahnejad, Vahid Asgary, Samaneh Heidarzadeh, Hoda Mazaheri, Samira Louni Aligoudarzi
Miscarriage is the most common complication in pregnancy. Considering the importance of the problem thrombophilia in pregnant women and its association with recurrent pregnancy loss (RPL), analysis of polymorphisms of genes involved in thrombophilia can be useful. We investigated the frequency and association between ten polymorphisms of seven thrombophilia genes and RPL in an Iranian population. This case-control study was conducted on 200 women with recurrent pregnancy loss and also on 200 women with at least one successful pregnancy as the control group...
April 15, 2018: Systems Biology in Reproductive Medicine
Mohammad Hasanzadeh, Fozieh Mokhtari, Vahid Jouyban-Gharamaleki, Ahad Mokhtarzadeh, Nasrin Shadjou
This study reports on the electropolymerization of a low toxic and biocompatible nanopolymer with entitle poly arginine-graphene quantum dots-chitosan (PARG-GQDs-CS) as a novel strategy for surface modification of glassy carbon surface and preparation of a new interface for measurement of malondialdehyde (MDA) in exhaled breath condensate. Electrochemical deposition, as a well-controlled synthesis procedure, has been used for subsequently layer-by-layer preparation of GQDs-CS nanostructures on a PARG prepolymerized on the surface of glassy carbon electrode using cyclic voltammetry techniques in the regime of -1...
April 15, 2018: Journal of Molecular Recognition: JMR
Vahid Sebghatollahi, Maryam Soheilipour, Mahsa Khodadoostan, Alireza Shavakhi, Ahmad Shavakhi
Background: This study evaluated the clinical efficacy and tolerability of a 14-day course of bismuth-based quadruple therapy including tinidazole and levofloxacin in compare to a 14-day bismuth-based quadruple therapy including clarithromycin as first-line treatment for Helicobacter pylori infection in Iranian adults. Materials and Methods: The study was a prospective, parallel group, randomized controlled, clinical trial that conducted on 150 patients with H. pylori infection...
2018: Advanced Biomedical Research
François Bertaux, Samuel Marguerat, Vahid Shahrezaei
The cell division rate, size and gene expression programmes change in response to external conditions. These global changes impact on average concentrations of biomolecule and their variability or noise. Gene expression is inherently stochastic, and noise levels of individual proteins depend on synthesis and degradation rates as well as on cell-cycle dynamics. We have modelled stochastic gene expression inside growing and dividing cells to study the effect of division rates on noise in mRNA and protein expression...
March 2018: Royal Society Open Science
Matthew A Stott, Vahid Ganjalizadeh, Maclain Olsen, Marcos Orfila, Johnny McMurray, Holger Schmidt, Aaron R Hawkins
Multimode interference (MMI) waveguides can be used for multiplexing and de-multiplexing optical signals. High fidelity, wavelength dependent multi-spot patterns from MMI waveguides are useful for sensitive and simultaneous identification of multiple targets in multiplexed fluorescence optofluidic biosensors. Through experiments and simulation, this paper explores design parameters for an MMI rib anti-resonant reflecting optical waveguide (ARROW) in order to produce high fidelity spot patterns at the liquid core biomarker excitation region...
June 2018: IEEE Journal of Quantum Electronics
Monika Haemmerle, Rebecca L Stone, David G Menter, Vahid Afshar-Kharghan, Anil K Sood
Besides their function in limiting blood loss and promoting wound healing, experimental evidence has highlighted platelets as active players in all steps of tumorigenesis including tumor growth, tumor cell extravasation, and metastasis. Additionally, thrombocytosis in cancer patients is associated with adverse patient survival. Due to the secretion of large amounts of microparticles and exosomes, platelets are well positioned to coordinate both local and distant tumor-host crosstalk. Here, we present a review of recent discoveries in the field of platelet biology and the role of platelets in cancer progression as well as challenges in targeting platelets for cancer treatment...
March 19, 2018: Cancer Cell
Vahid Mirshafiee, Brendan A C Harley, Mary L Kraft
Characterization of the heterogeneity within stem cell populations, which affects their differentiation potential, is necessary for the design of artificial cultures for stem cell expansion. In this study, we assessed whether self-organizing maps (SOMs) of single cell time-of-flight secondary ion mass spectrometry (TOF-SIMS) data provide insight into the spectral, and thus the related functional heterogeneity between and within three hematopoietic cell populations. SOMs were created of TOF-SIMS data from individual hematopoietic stem and progenitor cells (HSPCs), lineage-committed common lymphoid progenitors (CLPs), and fully differentiated B cells that had been isolated from murine bone marrow via conventional flow cytometry...
March 16, 2018: Tissue Engineering. Part C, Methods
Michail N Isupov, Ewald Schröder, Robert P Gibson, Jean Beecher, Giuliana Donadio, Vahid Saneei, Stephlina A Dcunha, Emma J McGhie, Christopher Sayer, Colin F Davenport, Peter C K Lau, Yoshie Hasegawa, Hiroaki Iwaki, Maria Kadow, Kathleen Balke, Uwe T Bornscheuer, Gleb Bourenkov, Jennifer A Littlechild
A statement is amended in the article by Isupov et al. [(2015). Acta Cryst. D71, 2344-2353].
April 1, 2018: Acta Crystallographica. Section D, Structural Biology
Pietro Quaglio, Vahid Rostami, Emiliano Torre, Sonja Grün
Temporally, precise correlations between simultaneously recorded neurons have been interpreted as signatures of cell assemblies, i.e., groups of neurons that form processing units. Evidence for this hypothesis was found on the level of pairwise correlations in simultaneous recordings of few neurons. Increasing the number of simultaneously recorded neurons increases the chances to detect cell assembly activity due to the larger sample size. Recent technological advances have enabled the recording of 100 or more neurons in parallel...
April 12, 2018: Biological Cybernetics
Mohammad Arhami, Maryam Zare Shahne, Vahid Hosseini, Navid Roufigar Haghighat, Alexandra M Lai, James J Schauer
Currently PM2.5 is a major air pollution concern in Tehran, Iran due to frequent high levels and possible adverse impacts. In this study, which is the first of its kind to take place in Tehran, composition and sources of PM2.5 and carbonaceous aerosol were determined, and their seasonal trends were studied. In this regard, fine PM samples were collected every six days at a residential station for one year and the chemical constituents including organic marker species, metals, and ions were analyzed by chemical analysis...
April 9, 2018: Environmental Pollution
Hossein Jamali, Vahid Beigi, Ali Sadeghi-Sarvestani
Heredity plays an important role in keratoconus (KC). Consanguineous marriage (CM) can affect the transmission of recessively inherited conditions. We aimed to investigate the role of consanguineous marriage in the development of KC. This study included two groups: the first group comprised 415 patients who underwent surgery for KC for the first time at Khalili University Hospital (Shiraz, Iran), between 2010 and 2014; the second group comprised 415 healthy individuals who served as age- and sex-matched controls for the patient group...
2018: Medical Hypothesis, Discovery and Innovation in Ophthalmology
Mahmoud Najafi, Vahid Khosravani, Meysam Shahhosseini, Amirhossein Afshari
OBJECTIVES: It has been shown that smoking may be affected by metacognitions. This study aimed to evaluate the factor structure, reliability and validity of the Persian version of the Metacognitions about Smoking Questionnaire (MSQ) among a sample of Iranian male smokers. METHODS: When the English to Persian translation of the MSQ was performed, exploratory factor analysis (EFA) and confirmatory factor analysis (CFA) were completed according to the four-factor solution of the original MSQ...
March 18, 2018: Addictive Behaviors
Amir Afkham, Leili Aghebati-Maleki, Homayoon Siahmansouri, Sanam Sadreddini, Majid Ahmadi, Sanam Dolati, Nahid Manafi Afkham, Parvin Akbarzadeh, Farhad Jadidi-Niaragh, Vahid Younesi, Mehdi Yousefi
BACKGROUND: Prostate cancer is known as the most common malignancy in men. Chitosan has generated great interest as a useful biopolymer for the encapsulation of small interfering RNA (siRNA). Due to cationic nature, chitosan is able to efficiently encapsulate siRNA molecules and form nanoparticles. Furthermore, the biocompatible and biodegradable attributes of chitosan have paved the way for its potential application in the in vivo delivery of therapeutic siRNAs. In this study, we aimed to design chitosan/CMD nanoparticles for the efficient encapsulation of the anti-cancer drugs SN38 and Snail-specific siRNA...
November 20, 2017: Pharmacological Reports: PR
Hasan Zare Khormizi, Mohammad Ali Salehinejad, Michael A Nitsche, Vahid Nejati
Negative effects of sleep deprivation on different types of memory are well documented, but the specific effects on autobiographical memory performance are not well studied. In this study, we investigated performance on the autobiographical memory test in a group of sleep-deprived and well-rested nurses. One-hundred participants divided into sleep-deprived (N = 50, 25 females) and well-rested (N = 50, 25 females) groups took part in the study. The sleep-deprived group included night-shift nurses with 8-12 hr sleep deprivation, while the well-rested group had the usual night sleep before performance assessment...
April 6, 2018: Journal of Sleep Research
Vahid Farina, Safora Salemi, Faezeh Tatari, Nasrin Abdoli, Touraj Ahmadi Jouybari, Mostafa Alikhani, Behrad Basanj, Ali Zakiei
BACKGROUND: Child abuse and violence toward children has become a complex phenomenon in nowadays societies leaving hurt children with numerous complications such as lowered self-efficacy. Hence, this study was conducted to assess the effect of trauma-focused cognitive behavioral therapy (TF-CBT) in physically abused children self-efficacy. MATERIALS AND METHODS: This study was a randomized clinical trial. From this statistical population of all abused children aged 9-12 in Kermanshah in 2016-2017, 40 were divided into intervention and control groups randomly...
2018: Journal of Education and Health Promotion
Vahid Aslanzadeh, Yuanhua Huang, Guido Sanguinetti, Jean D Beggs
No abstract text is available yet for this article.
April 2018: Genome Research
Vahid Karimi, Arash Ghalyanchilangeroudi, Masoud Hashemzadeh, Forough Rahimi, Mohammad Taha Zabihi Petroudi, Reza Kh Farahani, Hossein Maghsoudloo, Hamed Abdollahi
[This corrects the article DOI: 10.1007/s13337-017-0414-4.].
March 2018: Virusdisease
Vahid Karimi, Arash Ghalyanchilangeroudi, Masoud Hashemzadeh, Forough Rahimi, Mohammad Taha Zabihi Petroudi, Reza Kh Farahani, Hossein Maghsoudloo, Hamed Abdollahi
Infectious bronchitis (IB) is a highly infectious avian pathogen, which affects the respiratory tract, gut, reproductive system, and kidney of chicks of all ages. Many different serotypes of IB virus (IBV) are recognized which cause different clinical manifestations. According to the antigenic differences, different serotypes of the virus do not cross-protect. Massachusetts serotype induces the best cross-protection against other serotypes. Recently, the IBV QX strain has been detected in Iran. QX strain causes permanent damage to the oviduct if it occurs in the early life cycle and is a significant factor in layer and breeder chicken flocks...
March 2018: Virusdisease
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