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pityriasis rosea

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https://www.readbyqxmd.com/read/27862158/the-role-of-interleukin-22-in-pityriasis-rosea
#1
S Al Mokadem, S Ghonemy, A Zidan, G Abd El Aleem
BACKGROUND: Pityriasis rosea (PR) is an exanthematous disease related to reactivation of human herpes virus (HHV) types 6 and 7. The pathogenesis and cytokine profile of PR are still poorly understood.There is a large amount of evidence indicating a viral aetiology for PR. AIM: To measure the serum level of interleukin (IL)-22, a cytokine expressed by T helper (Th)17 cells in patients with PR to explore the possible association of IL-22 with the pathogenesis of the disease...
November 11, 2016: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/27805921/c-cbl-e3-ubiquitin-ligase-expression-increases-across-the-spectrum-of-benign-and-malignant-t-cell-skin-diseases
#2
Katrin A Salva, Margo J Reeder, Rita Lloyd, Gary S Wood
Prolonged survival of lesional T cells plays a central role in the pathogenesis of T-cell-mediated dermatoses. We have recently shown that the ubiquitin ligase c-CBL is highly expressed in cutaneous T-cell lymphoma (CTCL) and that its knockdown increases activation-induced cell death, a key pathway for T-cell apoptosis. Here, we extend our work on c-CBL expression in malignant T cells to their nonneoplastic counterparts in benign inflammatory dermatoses. Immunohistochemical staining with anti-c-CBL antibody was performed on lesional biopsies from a total of 65 patients with atopic dermatitis, allergic contact dermatitis, pityriasis rosea, psoriasis vulgaris, lichen planus, mycosis fungoides (MF)/Sézary syndrome (SS) as well as on tonsil tissue from 5 individuals and on 5 human CTCL cell lines...
October 31, 2016: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/27766674/cutaneous-metastasis-of-inflammatory-breast-carcinoma-mimicking-an-erythema-annulare-centrifugum-a-sign-of-locally-recurrent-cancer
#3
V Sabater, F Ferrando, A Morera, L Palomar
Erythema annulare centrifugum (EAC) is a clinical reaction pattern that includes lupus erythematosus, spongiotic dermatitis (particularly pityriasis rosea), pseudolymphoma and cutaneous B-cell lymphoma. However, it can be the result of cutaneous metastasis by an internal carcinoma. We present the case of a 38-year-old woman with bilateral inflammatory breast cancer following multimodal therapy. After chemotherapy, the patient developed EAC on her back, clinically suspect of subacute cutaneous lupus erythematosus...
October 20, 2016: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/27730050/is-a-treatment-for-pityriasis-rosea-really-needed
#4
Giulia Ciccarese, Francesco Drago
No abstract text is available yet for this article.
September 2016: Indian Dermatology Online Journal
https://www.readbyqxmd.com/read/27648382/pityriasis-rosea-in-pregnancy-report-of-a-spousal-occurrence-and-craniosynostosis-in-the-healthy-newborn
#5
REVIEW
Tiffany Y Loh, Philip R Cohen
BACKGROUND: Pityriasis rosea is a papulosquamous disease. It may occur during pregnancy; in this setting, it has occasionally been associated with adverse outcomes. PURPOSE: A woman who developed pityriasis rosea at the beginning of her eighth week of gestation is described. The outcomes in newborns delivered by pregnant women who developed pityriasis rosea during gestation are summarized. METHOD: A 28-year-old woman developed pityriasis rosea during her eighth week of pregnancy...
July 2016: Dermatology Practical & Conceptual
https://www.readbyqxmd.com/read/27613297/dermoscopy-in-general-dermatology-a-practical-overview
#6
REVIEW
Enzo Errichetti, Giuseppe Stinco
Over the last few years, dermoscopy has been shown to be a useful tool in assisting the noninvasive diagnosis of various general dermatological disorders. In this article, we sought to provide an up-to-date practical overview on the use of dermoscopy in general dermatology by analysing the dermoscopic differential diagnosis of relatively common dermatological disorders grouped according to their clinical presentation, i.e. dermatoses presenting with erythematous-desquamative patches/plaques (plaque psoriasis, eczematous dermatitis, pityriasis rosea, mycosis fungoides and subacute cutaneous lupus erythematosus), papulosquamous/papulokeratotic dermatoses (lichen planus, pityriasis rosea, papulosquamous sarcoidosis, guttate psoriasis, pityriasis lichenoides chronica, classical pityriasis rubra pilaris, porokeratosis, lymphomatoid papulosis, papulosquamous chronic GVHD, parakeratosis variegata, Grover disease, Darier disease and BRAF-inhibitor-induced acantholytic dyskeratosis), facial inflammatory skin diseases (rosacea, seborrheic dermatitis, discoid lupus erythematosus, sarcoidosis, cutaneous leishmaniasis, lupus vulgaris, granuloma faciale and demodicidosis), acquired keratodermas (chronic hand eczema, palmar psoriasis, keratoderma due to mycosis fungoides, keratoderma resulting from pityriasis rubra pilaris, tinea manuum, palmar lichen planus and aquagenic palmar keratoderma), sclero-atrophic dermatoses (necrobiosis lipoidica, morphea and cutaneous lichen sclerosus), hypopigmented macular diseases (extragenital guttate lichen sclerosus, achromic pityriasis versicolor, guttate vitiligo, idiopathic guttate hypomelanosis, progressive macular hypomelanosis and postinflammatory hypopigmentations), hyperpigmented maculopapular diseases (pityriasis versicolor, lichen planus pigmentosus, Gougerot-Carteaud syndrome, Dowling-Degos disease, erythema ab igne, macular amyloidosis, lichen amyloidosus, friction melanosis, terra firma-forme dermatosis, urticaria pigmentosa and telangiectasia macularis eruptiva perstans), itchy papulonodular dermatoses (hypertrophic lichen planus, prurigo nodularis, nodular scabies and acquired perforating dermatosis), erythrodermas (due to psoriasis, atopic dermatitis, mycosis fungoides, pityriasis rubra pilaris and scabies), noninfectious balanitis (Zoon's plasma cell balanitis, psoriatic balanitis, seborrheic dermatitis and non-specific balanitis) and erythroplasia of Queyrat, inflammatory cicatricial alopecias (scalp discoid lupus erythematosus, lichen planopilaris, frontal fibrosing alopecia and folliculitis decalvans), nonscarring alopecias (alopecia areata, trichotillomania, androgenetic alopecia and telogen effluvium) and scaling disorders of the scalp (tinea capitis, scalp psoriasis, seborrheic dermatitis and pityriasis amiantacea)...
December 2016: Dermatology and Therapy
https://www.readbyqxmd.com/read/27558764/atypical-pityriasis-rosea-clinical-evaluation-of-27-patients
#7
Fadime Kilinc, Ayse Akbas, Sertac Sener, Akın Aktaş
BACKGROUND: Pityriasis rosea (PR) is a common, acute, self-limiting inflammatory skin disease. It can easily be recognized with its typical clinical presentation. However, unusual clinic presentations can cause difficulty in diagnosis. Up to now, not many atypical forms are reported. OBJECTIVE: To determine the clinical characteristics of patients with atypical pityriasis rosea. METHODS: A total of 27 cases, diagnosed as atypical PR by clinical and/or histopathological examination and applied to the outpatient clinic of dermatology department between the years 2007 and 2015 were analyzed retrospectively...
September 26, 2016: Cutaneous and Ocular Toxicology
https://www.readbyqxmd.com/read/27513966/anesthetic-considerations-for-neuraxial-anesthesia-in-pregnant-patients-with-pityriasis-rosea-with-skin-lesions-covering-the-lumbar-spine
#8
Megan Werntz, Carlene Chun, Brandon Michael Togioka
Pityriasis rosea (PR) is an acute exanthematous skin disease that is likely due to reactivation of human herpesviruses (HHVs) 6b and 7. In contrast to herpes simplex and zoster (alphaherpesviruses), HHV-6b and -7 (betaherpesviruses) are not found predominantly in skin lesions. This difference in virion location may decrease the possibility of causing central nervous system infection through skin contamination, but the risk for hematogenous spread likely remains the same. This article uses the first-known epidural placement through active PR to illustrate risk-benefit considerations when deciding between neuraxial and general anesthesia for obstetric patients with PR...
October 15, 2016: A & A Case Reports
https://www.readbyqxmd.com/read/27512182/pityriasis-rosea-an-update-on-etiopathogenesis-and-management-of-difficult-aspects
#9
REVIEW
Khushbu Mahajan, Vineet Relhan, Aditi Kochhar Relhan, Vijay Kumar Garg
Pityriasis rosea (PR) is a benign papulosquamous disorder seen commonly in clinical practice. Despite its prevalence and benign nature, there are still times when this common disorder presents in an uncommon way or course posing diagnostic or management problems for the treating physician. The etiopathogenesis of PR has always been a dilemma, and extensive research is going on to elicit the exact cause. This review focuses mainly on the difficult aspects of this benign common disorder such as etiopathogenesis, atypical manifestations, recurrent cases, differential diagnosis, therapy and pregnancy considerations...
July 2016: Indian Journal of Dermatology
https://www.readbyqxmd.com/read/27504295/clinicopathological-study-of-non-infectious-erythaematous-papulosquamous-skin-diseases
#10
Sushma Hosamane, Muktha Pai, Thoppil Reba Philipose, Umaru Nayarmoole
INTRODUCTION: Papulosquamous diseases are characterized by scaly papules and plaques with similar clinical picture which amounts to confusion and hence, a definitive histopathological diagnosis goes a long way in treatment of such diseases. AIM: The aim of the study was to study the histomorphology of non-infectious, erythaematous, papulosquamous lesions of skin with clinicopathological correlation. MATERIALS AND METHODS: Skin biopsies from 150 clinically diagnosed/suspected non-infectious erythaematous, papulosquamous skin diseases were received in the Department of Pathology...
June 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27406919/a-position-statement-on-the-management-of-patients-with-pityriasis-rosea
#11
A Chuh, V Zawar, G Sciallis, W Kempf
Many clinical trials have been conducted on the treatment of pityriasis rosea (PR). Our aim was to establish a position statement for the management of adults with PR based on the best available evidence. We searched PubMed for all reports on randomized controlled trials for the treatment of PR published in the past 30 years. We retrieved 14 articles reporting randomized controlled trials, and found five which met our quality requirements for in-depth analyses. Erythromycin was found in a well-conducted triple-blind study to cast significant impacts on clinical outcomes...
July 13, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/27396667/a-herald-patch-almost-encircling-the-trunk-extreme-pityriasis-rosea-gigantea-in-a-young-child
#12
Antonio Chuh
An 18-month-old girl presented with pityriasis rosea gigantea. The herald patch encircled almost the entire trunk. The distribution of lesions on the trunk and proximal aspects of the limbs, the collarette scaling, the orientation of some lesions along the skin crease lines, and biopsy findings substantiated the diagnosis.
September 2016: Pediatric Dermatology
https://www.readbyqxmd.com/read/27294066/a-case-series-of-erythema-multiforme-like-pityriasis-rosea
#13
Anupam Das, Tushar K Sarkar, Somodyuti Chandra, Anupama Ghosh, Ramesh Chandra Gharami
No abstract text is available yet for this article.
May 2016: Indian Dermatology Online Journal
https://www.readbyqxmd.com/read/27265071/inflammatory-and-glandular-skin-disease-in-pregnancy
#14
Catherine S Yang, Mary Teeple, Jennie Muglia, Leslie Robinson-Bostom
A switch from cell-mediated to humoral immunity (helper T 1 [Th1] to helper T 2 [Th2] shift) during gestation plays a key role in placental immune tolerance. As a result, skin diseases that are Th2 mediated often worsen, whereas skin diseases that are Th1 mediated often improve during gestation. Also, due to fluctuations in glandular activity, skin diseases involving sebaceous and eccrine glands may flare, whereas those involving apocrine glands may improve during pregnancy. Despite these trends, inflammatory and glandular skin diseases do not always follow the predicted pattern, and courses are often diverse...
May 2016: Clinics in Dermatology
https://www.readbyqxmd.com/read/27222672/red-cell-distribution-width-and-mean-platelet-volume-in-patients-with-pityriasis-rosea
#15
Gunseli Sefika Pancar, Oznur Eyupoglu
BACKGROUND: Pityriasis rosea (PR) is an inflammatory skin disorder of unknown etiology. However, it is suggested to be related with the reactivation of human herpes virus 7 (HHV-7) and/or HHV-6. It is sometimes diffucult to distinguish PR from PR-like drug eruptions and other inflammatory disorders, so we need new parameters which are cheap and easy in determining PR. Red blood cell distribution width (RDW) and mean platelet volume (MPV) have been studied as inflammatory markers in recent studies...
June 2016: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/27212277/acyclovir-is-not-effective-in-pityriasis-rosea-results-of-a-randomized-triple-blind-placebo-controlled-trial
#16
Sanjay Singh, Narendra K Tiwary
BACKGROUND: Acyclovir is considered to be an effective treatment for pityriasis rosea but randomized, blinded, placebo-controlled trials have not been performed. AIMS: To test the efficacy of acyclovir in pityriasis rosea in a randomized, triple-blind, placebo-controlled trial. METHODS: Twenty seven patients with pityriasis rosea were randomly allocated to receive placebo (n = 13) or acyclovir (800 mg five times daily for one week) (n = 14)...
September 2016: Indian Journal of Dermatology, Venereology and Leprology
https://www.readbyqxmd.com/read/27103975/pityriasis-rosea-gianotti-crosti-syndrome-asymmetric-periflexural-exanthem-papular-purpuric-gloves-and-socks-syndrome-eruptive-pseudoangiomatosis-and-eruptive-hypomelanosis-do-their-epidemiological-data-substantiate-infectious-etiologies
#17
REVIEW
Antonio Chuh, Vijay Zawar, Gabriel F Sciallis, Werner Kempf, Albert Lee
Many clinical and laboratory-based studies have been reported for skin rashes which may be due to viral infections, namely pityriasis rosea (PR), Gianotti-Crosti syndrome (GCS), asymmetric periflexural exanthem/unilateral laterothoracic exanthem (APE/ULE), papular-purpuric gloves and socks syndrome (PPGSS), and eruptive pseudo-angiomatosis (EP). Eruptive hypomelanosis (EH) is a newly discovered paraviral rash. Novel tools are now available to investigate the epidemiology of these rashes. To retrieve epidemiological data of these exanthema and analyze whether such substantiates or refutes infectious etiologies...
March 21, 2016: Infectious Disease Reports
https://www.readbyqxmd.com/read/27096928/pityriasis-rosea-a-comprehensive-classification
#18
Francesco Drago, Giulia Ciccarese, Alfredo Rebora, Francesco Broccolo, Aurora Parodi
Pityriasis rosea (PR) is an acute, self-limiting exanthematous disease associated with the endogenous systemic reactivation of human herpesvirus (HHV)-6 and/or HHV-7. The disease typically begins with a single, erythematous plaque followed by a secondary eruption with lesions on the cleavage lines of the trunk (configuration of a 'Christmas tree'). The duration may vary from 2 weeks to a few months. Besides the typical presentation of PR, atypical forms have been described. The previous classifications of PR are mainly based on its atypical morphological features rather than on the pathogenetic mechanisms that underlie the different presentations of the disease...
2016: Dermatology: International Journal for Clinical and Investigative Dermatology
https://www.readbyqxmd.com/read/27061329/seasonal-variations-in-dermatologic-and-dermatopathologic-diagnoses-a-retrospective-15-year-analysis-of-dermatopathologic-data
#19
Jeff D Harvell, Daniel J Selig
BACKGROUND: Certain dermatologic conditions are known to show seasonal variations in frequency, the reasons for which are unclear but in some cases may be attributable to changes in ambient weather conditions. OBJECTIVES: The current study was conducted to determine whether seasonal trends might exist for dermatologic conditions including erythema multiforme, guttate psoriasis, erythema dyschromicum perstans (ashy dermatosis), pityriasis lichenoides, and pityriasis rosea...
October 2016: International Journal of Dermatology
https://www.readbyqxmd.com/read/27009931/sex-differences-in-the-incidence-of-skin-and-skin-related-diseases-in-olmsted-county-minnesota-united-states-and-a-comparison-with-other-rates-published-worldwide
#20
REVIEW
Louise K Andersen, Mark D P Davis
Many skin and skin-related diseases affect the sexes unequally, with attendant implications for public health and resource allocation. To evaluate better the incidence of skin and skin-related diseases affecting males vs. females, we reviewed published population-based epidemiology studies of skin disorders performed utilizing Rochester Epidemiology Project data. Females had a higher incidence of the following diseases: connective tissue diseases (scleroderma, morphea, dermatomyositis, primary Sjögren syndrome, systemic lupus erythematosus [not in all studies]), pityriasis rosea, herpes progenitalis, condyloma acuminatum, hidradenitis suppurativa, herpes zoster (except in children), erythromelalgia, venous stasis syndrome, and venous ulcers...
September 2016: International Journal of Dermatology
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