Yin-Cui Wu, Qi Yan, Si-Qing Yue, Lin-Xin Pan, Da-Shuai Yang, Liang-Song Tao, Ze-Yuan Wei, Fan Rong, Cheng Qian, Meng-Qi Han, Fu-Cheng Zuo, Jun-Fa Yang, Jia-Jia Xu, Zheng-Rong Shi, Jian Du, Zhao-Lin Chen, Tao Xu
Nonalcoholic fatty liver disease (NAFLD) is one of the common causes of chronic liver disease in the world. The problem of NAFLD had become increasingly prominent. However, its pathogenesis is still indistinct. As we all know, NAFLD begins with the accumulation of triglyceride (TG), leading to fatty degeneration, inflammation and other liver tissues damage. Notably, structure of nucleoporin 85 (NUP85) is related to lipid metabolism and inflammation of liver diseases. In this study, the results of researches indicated that NUP85 played a critical role in NAFLD...
2024: International Journal of Biological Sciences