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https://www.readbyqxmd.com/read/28550178/severity-of-structural-and-functional-right-ventricular-remodeling-depends-on-training-load-in-an-experimental-model-of-endurance-exercise
#1
Maria Sanz-de la Garza, Cira Rubies, Montserrat Batlle, Bart Bijnens, Lluís Mont, Marta Sitges, Eduard Guasch
An arrhythmogenic right ventricle (RV) remodeling has been reported in response to regular training, but it remains unclear how exercise intensity affects the presence and extent of such remodeling. We aimed at assessing the relationship between RV remodeling and exercise load in a long-term endurance training model. Wistar rats were conditioned to run at moderate (MOD, 45 min, 30cm/s) or intense (INT, 60 min, 60cm/s) workloads for 16 weeks; sedentary rats (SED) served as controls. Cardiac remodeling was assessed with standard echocardiographic and tissue Doppler techniques, sensor-tip pressure catheters and pressure-volume loop analyses...
May 26, 2017: American Journal of Physiology. Heart and Circulatory Physiology
https://www.readbyqxmd.com/read/28548989/imaging-adult-patients-with-fontan-circulation
#2
Salil Ginde, Benjamin H Goot, Peter C Frommelt
PURPOSE OF REVIEW: Survival after the Fontan procedure for palliation of single ventricle congenital heart disease has improved. However, adults with Fontan circulation are at risk for several complications including heart failure, thromboembolism, and protein-losing enteropathy. This review discusses the role of noninvasive imaging for surveillance and early detection of anatomic and functional abnormalities of the Fontan circulation that can impact the risk for Fontan failure over time...
May 25, 2017: Current Opinion in Cardiology
https://www.readbyqxmd.com/read/28545859/cardiac-shear-wave-elastography-using-a-clinical-ultrasound-system
#3
Mihai Strachinaru, Johan G Bosch, Bas M van Dalen, Lennart van Gils, Antonius F W van der Steen, Nico de Jong, Marcel L Geleijnse, Hendrik J Vos
The propagation velocity of shear waves relates to tissue stiffness. We prove that a regular clinical cardiac ultrasound system can determine shear wave velocity with a conventional unmodified tissue Doppler imaging (TDI) application. The investigation was performed on five tissue phantoms with different stiffness using a research platform capable of inducing and tracking shear waves and a clinical cardiac system (Philips iE33, achieving frame rates of 400-700 Hz in TDI by tuning the normal system settings)...
May 22, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28545398/advanced-glycation-end-products-in-children-with-type-1-diabetes-and-early-reduced-diastolic-heart-function
#4
Leif Brunvand, Martin Heier, Cathrine Brunborg, Kristian F Hanssen, Drude Fugelseth, Knut Haakon Stensaeth, Knut Dahl-Jørgensen, Hanna Dis Margeirsdottir
BACKGROUND: Reduced diastolic function is an early sign of diabetes cardiomyopathy in adults and is associated with elevated levels of HbA1c and advanced glycation end products (AGEs). OBJECTIVE: To assess the associations between early reduced diastolic function and elevated levels of HbA1c and AGEs in children and adolescents with type 1 diabetes (T1D). METHODS: One hundred fourty six T1D patients (age 8-18 years) without known diabetic complications were examined with tissue Doppler imaging and stratified into two groups according to diastolic function...
May 25, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28544277/use-of-a-vascular-closure-device-during-percutaneous-arterial-access-in-a-dog-with-impaired-hemostasis
#5
Brian A Scansen, Caitlin M Hokanson, Steven G Friedenberg, Hooman Khabiri
OBJECTIVE: To report the use of a vascular closure device (VCD) to provide rapid arterial hemostasis following percutaneous femoral arterial catheterization and diagnostic angiography in a thrombocytopenic and coagulopathic dog. CASE SUMMARY: A 6-year-old female spayed Kai Ken Tora dog presented after vehicular trauma. The dog was diagnosed with traumatic pneumothorax, degloving wounds of the right antebrachium, subcutaneous hemorrhage within the axillary tissues of the left thoracic limb, and anemia and thrombocytopenia secondary to acute hemorrhage...
May 23, 2017: Journal of Veterinary Emergency and Critical Care
https://www.readbyqxmd.com/read/28544108/elevated-intrathoracic-co2-pressure-during-thoracoscopic-surgery-decreases-regional-cerebral-oxygen-saturation-in-neonates-and-infants-a-pilot-study
#6
Felix Neunhoeffer, Steven W Warmann, Michael Hofbeck, Alisa Müller, Frank Fideler, Guido Seitz, Martin U Schuhmann, Hans-Joachim Kirschner, Matthias Kumpf, Jörg Fuchs
BACKGROUND: Intraoperative hypercapnia and acidosis are risk factors during thoracoscopy in neonates and infants. METHODS: In a prospective pilot study, we evaluated the effects of thoracoscopy in neonates and infants on cerebral microcirculation, oxygen saturation, and oxygen consumption. Regional cerebral oxygen saturation and blood flow were measured noninvasively using a new device combining laser Doppler flowmetry and white light spectrometry. Additionally, cerebral fractional tissue oxygen extraction and approximated oxygen consumption were calculated...
May 24, 2017: Paediatric Anaesthesia
https://www.readbyqxmd.com/read/28541158/noninvasive-optical-monitoring-of-critical-closing-pressure-and-arteriole-compliance-in-human-subjects
#7
Wesley B Baker, Ashwin B Parthasarathy, Kimberly P Gannon, Venkaiah C Kavuri, David R Busch, Kenneth Abramson, Lian He, Rickson C Mesquita, Michael T Mullen, John A Detre, Joel H Greenberg, Daniel J Licht, Ramani Balu, W Andrew Kofke, Arjun G Yodh
The critical closing pressure ( CrCP) of the cerebral circulation depends on both tissue intracranial pressure and vasomotor tone. CrCP defines the arterial blood pressure ( ABP) at which cerebral blood flow approaches zero, and their difference ( ABP -  CrCP) is an accurate estimate of cerebral perfusion pressure. Here we demonstrate a novel non-invasive technique for continuous monitoring of CrCP at the bedside. The methodology combines optical diffuse correlation spectroscopy (DCS) measurements of pulsatile cerebral blood flow in arterioles with concurrent ABP data during the cardiac cycle...
January 1, 2017: Journal of Cerebral Blood Flow and Metabolism
https://www.readbyqxmd.com/read/28540254/doppler-ultrasonography-of-the-pectinis-oculi-artery-in-harpy-eagles-harpia-harpyja
#8
Wanderlei de Moraes, Thiago A C Ferreira, André T Somma, Zalmir S Cubas, Bret A Moore, Fabiano Montiani-Ferreira
Twenty harpy eagles (Harpia harpyja) without systemic or ocular diseases were examined to measure blood velocity parameters of the pectinis oculi artery using Doppler ultrasonography. Pectinate artery resistive index (RI) and pulsatility index (PI) were investigated using ocular Doppler ultrasonography. The mean RI and PI values across all eyes were 0.44±0.10 and 0.62±0.20 respectively. Low RI and PI values found in the harpy eagle´s pectinis oculi artery compared with the American pekin ducks one and other tissue suggest indeed a high metabolic activity in pecten oculi and corroborates the hypothesis of a nutritional function and/or intraocular pressure regulation...
2017: Open veterinary journal
https://www.readbyqxmd.com/read/28530211/-pulse-wave-velocity-as-an-early-marker-of-diastolic-heart-failure-in-patients-with-hypertension
#9
Beata Moczulska, Monika Kubiak, Anna Bryczkowska, Ewa Malinowska
According to the WHO, hypertension is one of the major causes of death worldwide. It leads to a number of severe complications. Diastolic heart failure, that is heart failure with preserved ejection fraction (HFPEF), is especially common. New, but simple, indices for the early detection of patients who have not yet developed complications or are in their early developmental stages are still searched for. AIM: The aim of this study is to examine the correlation between pulse wave velocity (PWV) and markers of diastolic heart failure (DHF) assessed in echocardiography in patients with hypertension and no symptoms of heart failure...
April 21, 2017: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/28527847/self-repaired-process-of-a-traumatized-maxillary-central-incisor-with-pulp-infarct-after-horizontal-root-fracture-monitored-by-laser-doppler-flowmetry-combined-with-tissue-oxygen-monitor
#10
Qian Liao, Wenjun Ye, Junli Yue, Xiaoxi Zhao, Ling Zhang, Lan Zhang, Dingming Huang, Qinghua Zheng
Achieving a precise diagnosis of the pulp status of traumatized teeth is difficult. The time to interfere through endodontic treatment for these teeth is greatly dependent on the doctor's experience. A 24-year-old male patient suffered a traumatic injury to tooth #9 that resulted in an apical root horizontal fracture 3 days before he came to the hospital. The injured tooth showed no response to pulp sensitivity testing at the first visit and was discolored 1 week later. Tooth #9 was immobilized to its adjacent teeth for 4 weeks by a composite splint...
May 17, 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/28527195/changes-in-sternal-perfusion-following-internal-mammary-artery-bypass-surgery
#11
Christian D Taeger, Konstantin Klein, Raymund E Horch, Michael Weyand, Justus P Beier
BACKROUND: Coronary bypass surgery using the internal mammary artery (IMA) is among the most commonly performed procedures in treatment of advanced coronary vessel disease. Further, bilateral harvesting of the IMA is associated with increased rates of sternal wound infections. OBJECTIVE: This study aimed to explore changes in sternal perfusion, following left internal mammary artery (LIMA) harvesting. METHODS: 60 patients were divided equally into intervention- and control cohorts and underwent assessment of oxygen saturation (sO2) and relative blood flow (RBF) by laser doppler flowmetry remission spectroscopy preoperatively, 24 h and 72 h postoperatively...
May 18, 2017: Clinical Hemorheology and Microcirculation
https://www.readbyqxmd.com/read/28522095/the-reduction-of-central-sleep-apnoea-severity-in-the-left-lateral-position-is-not-due-to-an-improvement-in-cardiac-haemodynamics-in%C3%A2-patients-with-chronic-heart-failure
#12
Egidio Traversi, Davide Rossi, Roberto Maestri, Francesca Olmetti, Maria Teresa La Rovere, Gian Domenico Pinna
OBJECTIVE: The severity of central sleep apnoea (CSA), a common comorbidity in patients with chronic heart failure (CHF) and reduced ejection fraction, markedly decreases from the supine to the lateral sleeping position, with no difference between the left and right positions. The mechanisms responsible for this beneficial effect have not yet been elucidated. METHODS: We tested the hypothesis that CSA attenuation in the left lateral position is due, at least in part, to an improvement in cardiac haemodynamics...
June 2017: Sleep Medicine
https://www.readbyqxmd.com/read/28521901/noninvasive-imaging-analysis-of-biological-tissue-associated-with-laser-thermal-injury
#13
Cheng-Jen Chang, De-Yi Yu, Yen-Chang Hsiao, Kuang-Hua Ho
BACKGROUND: The purpose of our study is to use a noninvasive tomographic imaging technique with high spatial resolution to characterize and monitor biological tissue responses associated with laser thermal injury. METHODS: Optical doppler tomography (ODT) combines laser doppler flowmetry (LDF) with optical coherence tomography (OCT) to obtain high resolution tomographic velocity and structural images of static and moving constituents in highly scattering biological tissues...
April 2017: Biomedical Journal
https://www.readbyqxmd.com/read/28517999/venous-gas-emboli-and-ambulation-at-4-3-psia
#14
Johnny Conkin, Neal W Pollock, Michael J Natoli, Stefanie D Martina, James H Wessel, Michael L Gernhardt
INTRODUCTION: Ambulation during extravehicular activity on Mars may increase the risk of decompression sickness through enhanced bubble formation in the lower body. HYPOTHESES: walking effort (ambulation) before an exercise-enhanced denitrogenation (prebreathe) protocol at 14.7 psia does not increase the incidence of venous gas emboli (VGE) at 4.3 psia, but does increase incidence if performed after tissues become supersaturated with nitrogen at 4.3 psia. METHODS: VGE results from 45 control subjects who performed exercise prebreathe without ambulation before or during a 4-h exposure to 4...
April 1, 2017: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28514395/-impact-of-shock-wave-therapy-on-the-clinical-and-functional-status-of-patients-with-coronary-heart-disease
#15
S T Matskeplishvili, B M Borbodoeva, E U Asymbekova, A Z Rakhimov, N K Akhmedyarova, K B Kataeva, Yu I Buziashvili
AIM: To study of the impact of shock-wave therapy (SWT) on the functional status of patients with coronary heart disease (CHD). SUBJECTS AND METHODS: Thirty-four CHD patients (including 33 men) with left ventricular (LV) asynergic segments, as evidenced by echocardiography (EchoCG), were examined. Their mean age was 60.1±1.76 years. All the patients received a SWT cycle according to the standard scheme. The patient examination protocol involved EchoCG, dobutamine EchoCG, treadmill exercise EchoCG, and tissue Doppler EchoCG, which were performed at baseline, immediately and one month after the end of a SWT cycle...
2017: Terapevticheskiĭ Arkhiv
https://www.readbyqxmd.com/read/28514296/clinicopathological-features-and-differential-diagnosis-of-aggressive-angiomyxoma-of-the-female-pelvis-5-case-reports-and-literature-review
#16
Hong Chen, Hongyan Zhao, Yan Xie, Mulan Jin
Aggressive angiomyxoma (AAM) is a rare mesenchymal tumor that usually occurs in the pelvis and perineum of young females. AAM can simulate Bartholin's gland cyst, abscess, lipoma, simple labial cyst, or other pelvic soft tissue tumors. Here we present five cases of AAM with mean age of 42. The patients mainly presented slow-growing mass in the abdomen and perineum (3 cases in the pelvis, 1 in the vulva, and 1 in the buttock). Color Doppler flow imaging revealed blood flow for the 3 pelvic lesions. Enhanced computed tomography and magnetic resonance imaging of the other 2 cases showed the typical "swirled" or "layered" structure characteristic...
May 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28511151/peripheral-arteriovenous-fistula-as-vascular-access-for-long-term-chemotherapy
#17
Oleksiy O Kovalyov, Oleksandr G Kostyuk, Tetyana V Tkachuk
INTRODUCTION: To provide long-term vascular access in clinical oncology peripheral forearm veins (up to 95% of patients in Ukraine), central venous access and "complete implanted vascular systems" are used most often. Many oncology patients have contraindications to catheterization of superior vena cava. Besides, exploitation of central veins is associated with potential technical and infectious complications. The aim - to study short-term and long-term results of arteriovenous fistula exploitation as vascular access for continuous anticancer therapy...
2017: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/28509699/penis-transplantation-first-us-experience
#18
Curtis L Cetrulo, Kai Li, Harry M Salinas, Matthew D Treiser, Ilse Schol, Glen W Barrisford, Francis J McGovern, Adam S Feldman, Michael T Grant, Cigdem Tanrikut, Jeffrey H Lee, Richard J Ehrlichman, Paul W Holzer, Garry M Choy, Raymond W Liu, Zhi Yang Ng, Alexandre G Lellouch, Josef M Kurtz, William G Austen, Jonathan M Winograd, Branko Bojovic, Kyle R Eberlin, Ivy A Rosales, Robert B Colvin, Dicken S C Ko
OBJECTIVE: We describe the first successful penis transplant in the United States in a patient with a history of subtotal penectomy for penile cancer. BACKGROUND: Penis transplantation represents a new paradigm in restoring anatomic appearance, urine conduit, and sexual function after genitourinary tissue loss. To date, only 2 penis transplants have been performed worldwide. METHODS: After institutional review board approval, extensive medical, surgical, and radiological evaluations of the patient were performed...
May 15, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28506387/effects-of-atorvastatin-treatment-on-left-ventricular-diastolic-function-in-peritoneal-dialysis-patients-the-alevent-clinical-trial
#19
Cho-Kai Wu, Chih-Fan Yeh, Jiun-Yang Chiang, Ting-Tse Lin, Yi-Fan Wu, Chih-Kang Chiang, Tze-Wah Kao, Kuan-Yu Hung, Jenq-Wen Huang
BACKGROUND: Left ventricular diastolic dysfunction (LVDD) is common among patients undergoing peritoneal dialysis (PD). Increased levels of inflammatory biomarkers, such as high-sensitivity C-reactive protein, predict the development of LVDD. OBJECTIVES: We hypothesized that PD patients with elevated high-sensitivity C-reactive protein levels might benefit from statin treatment for LVDD and designed a randomized clinical trial to prove the hypothesis. METHODS: We screened 213 PD patients and randomly assigned 32 men and women with low-density lipoprotein cholesterol levels <130 mg/dL, high-sensitivity C-reactive protein levels of ≥1...
May 2017: Journal of Clinical Lipidology
https://www.readbyqxmd.com/read/28505080/first-insights-into-human-fingertip-regeneration-by-echo-doppler-imaging-and-wound-microenvironment-assessment
#20
Paris Jafari, Camillo Muller, Anthony Grognuz, Lee Ann Applegate, Wassim Raffoul, Pietro G di Summa, Sébastien Durand
Fingertip response to trauma represents a fascinating example of tissue regeneration. Regeneration derives from proliferative mesenchymal cells (blastema) that subsequently differentiate into soft and skeletal tissues. Clinically, conservative treatment of the amputated fingertip under occlusive dressing can shift the response to tissue loss from a wound repair process towards regeneration. When analyzing by Immunoassay the wound exudate from occlusive dressings, the concentrations of brain-derived neurotrophic factor (BDNF) and leukemia inhibitory factor (LIF) were higher in fingertip exudates than in burn wounds (used as controls for wound repair versus regeneration)...
May 13, 2017: International Journal of Molecular Sciences
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