keyword
https://read.qxmd.com/read/38532344/the-effects-of-an-iv-fluid-bolus-on-mitral-annular-velocity-and-the-assessment-of-diastolic-function-a-prospective-non-randomized-study
#1
JOURNAL ARTICLE
Sebastian Ayala, Orode Badakhsh, David Li, Neal W Fleming
BACKGROUND: Abnormal diastolic function is an independent predictor of adverse postoperative outcomes. Mitral annular tissue Doppler velocity (e') is a key parameter for assessing diastolic function. The purpose of this study was to confirm that an acute increase in preload did not significantly impact the intraoperative measurement of e' and secondarily evaluate the impact of this acute intravascular volume increase on the clinical assessment of diastolic function using a previously described simplified algorithm...
March 26, 2024: BMC Anesthesiology
https://read.qxmd.com/read/38531611/validation-and-incorporation-of-digital-entheses-into-a-preliminary-global-omeract-ultrasound-dactylitis-score-gloudas-in-psoriatic-arthritis
#2
JOURNAL ARTICLE
Esperanza Naredo, Maria Antonietta D Agostino, Lene Terslev, Carlos Pineda, M Isabel Miguel, Joan Blasi, George A Bruyn, Marion C Kortekaas, Peter Mandl, Rodina Nestorova, Marcin Szkudlarek, Plamen Todorov, Violeta Vlad, Priscilla Wong, Catherine Bakewell, Emilio Filippucci, Alen Zabotti, Mihaela Micu, Florentin Vreju, Mohamed Mortada, José Alexandre Mendonça, Carlos A Guillen-Astete, Otto Olivas-Vergara, Annamaria Iagnocco, Petra Hanova, Ilaria Tinazzi, Peter V Balint, Sibel Zehra Aydin, David Kane, Helen Keen, Gurjit S Kaeley, Ingrid Möller
OBJECTIVES: The main objective was to generate a GLobal OMERACT Ultrasound DActylitis Score (GLOUDAS) in psoriatic arthritis and to test its reliability. To this end, we assessed the validity, feasibility and applicability of ultrasound assessment of finger entheses to incorporate them into the scoring system. METHODS: The study consisted of a stepwise process. First, in cadaveric specimens, we identified enthesis sites of the fingers by ultrasound and gross anatomy, and then verified presence of entheseal tissue in histological samples...
March 26, 2024: Annals of the Rheumatic Diseases
https://read.qxmd.com/read/38531214/fetal-anemia-causes-placental-and-maternal-cellular-damage-a-lesson-from-fetal-hemoglobin-bart-s-disease
#3
JOURNAL ARTICLE
Suchaya Luewan, Nattayaporn Apaijai, Nipon Chattipakorn, Siriporn Chattipakorn, Theera Tongsong
INTRODUCTION: The studies about effect of fetal anemia on placental and maternal molecular changes have rarely been published. This study aimed to compare oxidative stress levels and mitochondrial function in the placenta and maternal peripheral blood mononuclear cell (PMBCs) between anemic fetuses (using fetal Hb Bart's disease as a study model) and non-anemic fetuses. METHODS: A cross-sectional study was conducted on pregnancies affected by Hb Bart's disease and non-anemic fetuses between 16 and 22 weeks of gestation...
March 21, 2024: Placenta
https://read.qxmd.com/read/38528818/the-effect-of-glucagon-like-peptide-1-receptor-agonists-on-cardiac-function-and-structure-in-patients-with-or-without-type-2-diabetes-mellitus-an-updated-systematic-review-and-meta-analysis
#4
JOURNAL ARTICLE
Yu Zhang, Danning Yang, Qiufeng Jia, Jie Yan, Fengshuang An
AIMS: To conduct an updated systematic review and meta-analysis to evaluate the efficacy of glucagon-like peptide-1 receptor agonists (GLP-1RAs) with regard to cardiac function and structure in people with or without type 2 diabetes mellitus (T2DM). MATERIALS AND METHODS: We conducted a systematic search using the PubMed, Embase and ClinicalTrials.gov online databases. The primary outcome of interest was changes in mitral inflow E-velocity to tissue Doppler e' velocity (E/e') ratio...
March 26, 2024: Diabetes, Obesity & Metabolism
https://read.qxmd.com/read/38518130/probabilistic-analysis-of-color-doppler-ultrasonography-for-breast-cancer-detection-in-asymptomatic-individuals
#5
JOURNAL ARTICLE
Jing Liu, Yang Zhao, Heling Zhang, Yupin Song
OBJECTIVE: This study aims to investigate and analyze the detection rate of breast cancer utilizing color Doppler ultrasonography in asymptomatic individuals. METHODS: A cohort of 500 female patients who underwent physical examinations at our hospital from January 2018 to August 2020 was selected for this research. The diagnosis involved conventional surgical palpation and color Doppler ultrasound in all cases. The control group underwent conventional surgical palpation, while the study group utilized the color Doppler ultrasound diagnosis method...
March 22, 2024: Alternative Therapies in Health and Medicine
https://read.qxmd.com/read/38516411/ovarian-tissue-transplantation-10-years-of-experience-at-the-bologna-university
#6
JOURNAL ARTICLE
Raffaella Fabbri, Rossella Vicenti, Valentina Magnani, Roberto Paradisi, Lucia De Meis, Diego Raimondo, Alessandro Arena, Stefano Venturoli, Antonio Raffone, Arianna Raspollini, Renato Seracchioli
OBJECTIVE: The efficiency of ovarian tissue transplantation (OTT) was established in terms of ovarian function recovery (95% of cases), number of live births (over 200 worldwide to date) and induction of puberty. Unfortunately, the lack of international registries and the fact that many centers have not yet reported their outcomes, lead to poor knowledge of the exact fertility data. The aim of the study is to describe our experience with OTT to restore ovarian function and fertility. METHODS: This study was designed as a single-center, observational, retrospective, cohort study that includes women who underwent OTT between December 2012 and June 2023 at our center...
2024: Frontiers in Endocrinology
https://read.qxmd.com/read/38515838/pharmacological-effects-and-target-analysis-of-guipi-wan-in-the-treatment-of-cerebral-ischemia-reperfusion-injury
#7
JOURNAL ARTICLE
Jianfeng Zhang, Li Luo, Yanyan Guo, An Liu, Mengjia Zhang, Wei Jiang, Xi Li, Qingqing Liu, Jiaoyan Yu
Guipi wan (GPW) is a traditional Chinese medicine commonly used in clinical practice, typically to treat neurological diseases such as neurasthenia and traumatic brain injury. It may have positive effects on cerebral ischemia‒reperfusion injury (cI/R). This study aimed to assess the effects of GPW in a mouse model of cI/R and find its possible targets. C57BL/6J mice were used to establish the cI/R model, and the laser speckle doppler was used to determine the success of the model. GPW was administered intragastrically for 7 days, brain tissue sections were stained with TTC, HE, and TUNEL, Western blot assay was performed to detect the effect of apoptosis-related proteins...
2024: Frontiers in Pharmacology
https://read.qxmd.com/read/38512023/association-of-impaired-left-ventricular-mitral-filling-from-4d-flow-cardiac-mri-and-prognosis-of-hypertrophic-cardiomyopathy
#8
JOURNAL ARTICLE
Hichem Sakhi, Gilles Soulat, Damian Craiem, Umit Gencer, Jérôme Lamy, Valentina Stipechi, Tania Puscas, Jean-Sébastien Hulot, Albert Hagege, Elie Mousseaux
Purpose To investigate whether the peak early filling rate normalized to the filling volume (PEFR/FV) estimated from four-dimensional (4D) flow cardiac MRI may be used to assess impaired left ventricular (LV) filling and predict clinical outcomes in individuals with hypertrophic cardiomyopathy (HCM). Materials and Methods Cardiac MRI with a 4D flow sequence and late gadolinium enhancement (LGE), as well as echocardiography, was performed in 88 individuals: 44 participants with HCM from a French prospective registry (ClinicalTrials...
April 2024: Radiology. Cardiothoracic imaging
https://read.qxmd.com/read/38510865/the-importance-of-differential-diagnosis-in-splenogonadal-fusion-a-case-report
#9
Inês Coelho Mogárrio, Carla Pilar, Ema Santos, Fátima Alves
Splenogonadal fusion is a rare, benign congenital malformation characterized by the association of splenic tissue and gonads (typically testicles). It is a condition of male predominance and can be classified into two types: continuous, if the spleen and gonad are united by a splenic cord or fibrous tissue, or discontinuous. Splenogonadal fusion is often associated with other congenital anomalies such as cryptorchidism, limb defects, and micrognathia. Differential diagnosis can be difficult and includes inguinal hernia, spermatic cord cyst, cryptorchidism, or testicular mass...
February 2024: Curēus
https://read.qxmd.com/read/38510621/developing-a-porcine-model-of-severe-traumatic-brain-injury-induced-by-high-amplitude-rotational-acceleration
#10
JOURNAL ARTICLE
Sofie Dietvorst, Aline Vervekken, Bart Depreitere
INTRODUCTION: It is unclear which pathophysiological processes initiate and drive dynamic cerebrovascular autoregulation (CA) impairment as seen in traumatic brain injury (TBI). This is not solely attributable to raised intracranial pressure (ICP), but also results from local tissue damage. RESEARCH QUESTION: In order to investigate CA disturbing processes, a porcine model is needed that mimics severe TBI as seen in humans. This model requires high amplitude rotational acceleration...
2024: Brain Spine
https://read.qxmd.com/read/38508082/an-8%C3%A2-mm-endoscopic-histotripsy-array-with-integrated-high-resolution-ultrasound-imaging
#11
JOURNAL ARTICLE
Matthew G Mallay, Thomas G Landry, Jeremy A Brown
An 8 mm diameter, image-guided, annular array histotripsy transducer was fabricated and characterized. The array was laser etched on a 5 MHz, 1-3 dice and fill, PZT-5H/epoxy composite with a 45 % volume fraction. Flexible PCBs were used to electrically connect to the array elements using wirebonds. The array was backed with a low acoustic impedance epoxy mixture. A 3.6 by 3.8 mm, 64-element, 30 MHz phased array imaging probe was positioned in the center hole, to co-align the imaging plane with the bubble cloud produced by the therapy array...
March 17, 2024: Ultrasonics
https://read.qxmd.com/read/38505490/deep-learning-from-atrioventricular-plane-displacement-in-patients-with-takotsubo-syndrome-lighting-up-the-black-box
#12
JOURNAL ARTICLE
Fahim Zaman, Nicholas Isom, Amanda Chang, Yi Grace Wang, Ahmed Abdelhamid, Arooj Khan, Majesh Makan, Mahmoud Abdelghany, Xiaodong Wu, Kan Liu
AIMS: The spatiotemporal deep convolutional neural network (DCNN) helps reduce echocardiographic readers' erroneous 'judgement calls' on Takotsubo syndrome (TTS). The aim of this study was to improve the interpretability of the spatiotemporal DCNN to discover latent imaging features associated with causative TTS pathophysiology. METHODS AND RESULTS: We applied gradient-weighted class activation mapping analysis to visualize an established spatiotemporal DCNN based on the echocardiographic videos to differentiate TTS (150 patients) from anterior wall ST-segment elevation myocardial infarction (STEMI, 150 patients)...
March 2024: European heart journal. Digital health
https://read.qxmd.com/read/38487995/the-impact-of-glucocorticoid-use-on-the-outcomes-of-rheumatoid-arthritis-in-a-multicenter-ultrasound-cohort-study
#13
JOURNAL ARTICLE
Fumiaki Nonaka, Shoichi Fukui, Tohru Michitsuji, Yushiro Endo, Ayako Nishino, Toshimasa Shimizu, Masataka Umeda, Remi Sumiyoshi, Tomohiro Koga, Naoki Iwamoto, Tomoki Origuchi, Yukitaka Ueki, Nobutaka Eiraku, Takahisa Suzuki, Akitomo Okada, Naoki Matsuoka, Hirokazu Takaoka, Hiroaki Hamada, Tomomi Tsuru, Yojiro Arinobu, Toshihiko Hidaka, Keita Fujikawa, Tamami Yoshitama, Yoshifumi Tada, Hideo Ohtsubo, Jun Ishizaki, Tomoyuki Asano, Takahiro Maeda, Atsushi Kawakami, Shin-Ya Kawashiri
OBJECTIVE: Glucocorticoids are effective in treating rheumatoid arthritis (RA) when used appropriately considering the balance of the risks and benefits, especially at low doses. We aimed to evaluate the response of biologic and targeted synthetic disease-modifying antirheumatic drugs (b/tsDMARDs) in patients having already been treated with glucocorticoids. METHODS: We reviewed RA patients treated with b/tsDMARDs in a prospective multicenter ultrasound cohort study...
March 2024: International Journal of Rheumatic Diseases
https://read.qxmd.com/read/38478454/3d-single-vessel-fractional-moving-blood-volume-3d-svfmbv-fully-automated-tissue-perfusion-estimation-using-ultrasound
#14
JOURNAL ARTICLE
Yi Yin, Alys R Clark, Sally L Collins
Power Doppler ultrasound (PD-US) is the ideal modality to assess tissue perfusion as it is cheap, patient-friendly and does not require ionizing radiation. However, meaningful inter-patient comparison only occurs if differences in tissue-attenuation are corrected for. This can be done by standardizing the PD-US signal to a blood vessel assumed to have 100% vascularity. The original method to do this is called fractional moving blood volume (FMBV). We describe a novel, fully-automated method combining image processing, numerical modelling, and deep learning to estimate three-dimensional single vessel fractional moving blood volume (3D-svFMBV)...
March 13, 2024: IEEE Transactions on Medical Imaging
https://read.qxmd.com/read/38477180/assessment-of-fetal-cardiac-functions-in-pregnant-women-with-anemia-prospective-case-control-study
#15
JOURNAL ARTICLE
Z Agaoglu, A Tanacan, U Gurbuz, M Ozturk Agaoglu, M Haksever, G Okutucu, O Kara, D Sahin
OBJECTIVE: To compare the fetal cardiac functions between pregnant women with iron deficiency anemia (IDA) and healthy controls. METHODS: This single-center, prospective, case-control study was conducted at a tertiary hospital. A total of 150 patients, including 50 patients with IDA and 100 healthy pregnant women at 30-34 weeks of gestation, were included in the study. Of the patients with anemia, 20 had mild anemia, 18 had moderate anemia, and 12 had severe anemia...
March 13, 2024: Ultrasound in Obstetrics & Gynecology
https://read.qxmd.com/read/38471997/patient-specific-vascular-flow-phantom-for-mri-and-doppler-ultrasound-imaging
#16
JOURNAL ARTICLE
Sadaf Soloukey, Bastian Generowicz, Esther Warnert, Geert Springeling, Joost Schouten, Chris De Zeeuw, Clemens Dirven, Arnaud Vincent, Pieter Kruizinga
OBJECTIVE: Intraoperative Doppler ultrasound imaging of human brain vasculature is an emerging neuro-imaging modality that offers vascular brain mapping with unprecedented spatiotemporal resolution. At present, however, access to the human brain using Doppler Ultrasound is only possible in this intraoperative context, posing a significant challenge for validation of imaging techniques. This challenge necessitates the development of realistic flow phantoms outside of the neurosurgical operating room as external platforms for testing hardware and software...
March 11, 2024: Ultrasound in Medicine & Biology
https://read.qxmd.com/read/38464326/dynamic-mode-decomposition-for-transient-cavitation-bubbles-imaging-in-pulsed-high-intensity-focused-ultrasound-therapy
#17
Minho Song, Oleg A Sapozhnikov, Vera A Khokhlova, Tatiana D Khokhlova
Pulsed high-intensity focused ultrasound (pHIFU) can induce sparse de novo inertial cavitation without the introduction of exogenous contrast agents, promoting mild mechanical disruption in targeted tissue. Because the bubbles are small and rapidly dissolve after each HIFU pulse, mapping transient bubbles and obtaining real-time quantitative metrics correlated to tissue damage are challenging. Prior work introduced Bubble Doppler, an ultrafast power Doppler imaging method as a sensitive means to map cavitation bubbles...
March 1, 2024: bioRxiv
https://read.qxmd.com/read/38461420/comparative-evaluation-of-shear-wave-elastography-elasticity-values-in-thyroid-nodules-with-cytology-results-and-ti-rads-scoring-in-differentiation-of-benign-malignant-nodules
#18
JOURNAL ARTICLE
Zafer Polat, Muzaffer Elmalı, Asli Tanrivermis Sayit, Cihan Kalkan, Murat Danacı, Mehmet Kefeli
PURPOSE: The aim of this prospective study was to investigate the diagnostic performance of shear wave elastography (SWE) in differentiating benign and malignant thyroid nodules and their correlation with the American College of Radiology Thyroid Imaging Reporting and Data System (ACR TI-RADS). METHODS: This prospective study included 370 thyroid nodules in 308 patients aged 18-70 years. All the patients underwent B-mode ultrasound (US), Doppler examination, and SWE and were given an ACR TI-RADS risk score before fine needle aspiration biopsy (FNAB) and/or surgery...
March 10, 2024: European Archives of Oto-rhino-laryngology
https://read.qxmd.com/read/38459668/excess-renin-is-attributed-to-the-combination-of-forward-and-backward-failure-in-hfref
#19
JOURNAL ARTICLE
Henrike Arfsten, Gregor Heitzinger, Suriya Prausmüller, Annika Weidenhammer, Georg Goliasch, Philipp E Bartko, Georg Spinka, Martin Hülsmann, Noemi Pavo
AIMS: Regulation of the renin-angiotensin system (RAS) in heart failure (HF) with reduced ejection fraction (HFrEF) still raises questions, as a large proportion of patients show normal renin levels despite manifest disease. Experimental venous congestion results in reduced renal perfusion pressure and stimulates renin secretion. We hypothesized that excess renin levels are mainly a result of right ventricular failure as a sequalae of left ventricular dysfunction. The study aimed to link right ventricular function (RVF) with renin levels and to investigate further contributors to excess RAS activation...
March 8, 2024: ESC Heart Failure
https://read.qxmd.com/read/38459660/dihydrocapsaicin-suppresses-the-sting-mediated-accumulation-of-ros-and-nlrp3-inflammasome-and-alleviates-apoptosis-after-ischemia-reperfusion-injury-of-perforator-skin-flap
#20
JOURNAL ARTICLE
Yingying Lai, Ningning Yang, Xuankuai Chen, Xianhui Ma, Zhuliu Chen, Chengji Dong, Gaoxiang Yu, Yingying Huang, Donghao Shi, Pin Fang, Kejian Fu, Renhao Jiang, Cong Mao, Jian Ding, Weiyang Gao
Avascular necrosis frequently occurs as a complication following surgery involving the distal perforator flap. Dihydrocapsaicin (DHC) can protect tissue from ischemia-reperfusion (I/R) injury, but its specific role in multizone perforator flaps remains unclear. In this study, the prospective target of DHC in the context of I/R injury was predicted using network pharmacology analysis. Flap viability was determined through survival area analysis, laser Doppler blood flow, angiograms, and histological examination...
March 8, 2024: Phytotherapy Research: PTR
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