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Jeremy hunt

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https://www.readbyqxmd.com/read/28450346/rachel-clarke-jeremy-hunt-i-m-after-you
#1
(no author information available yet)
No abstract text is available yet for this article.
April 27, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28420733/detection-of-interferon-alpha-protein-reveals-differential-levels-and-cellular-sources-in-disease
#2
Mathieu P Rodero, Jérémie Decalf, Vincent Bondet, David Hunt, Gillian I Rice, Scott Werneke, Sarah L McGlasson, Marie-Alexandra Alyanakian, Brigitte Bader-Meunier, Christine Barnerias, Nathalia Bellon, Alexandre Belot, Christine Bodemer, Tracy A Briggs, Isabelle Desguerre, Marie-Louise Frémond, Marie Hully, Arn M J M van den Maagdenberg, Isabelle Melki, Isabelle Meyts, Lucile Musset, Nadine Pelzer, Pierre Quartier, Gisela M Terwindt, Joanna Wardlaw, Stewart Wiseman, Frédéric Rieux-Laucat, Yoann Rose, Bénédicte Neven, Christina Hertel, Adrian Hayday, Matthew L Albert, Flore Rozenberg, Yanick J Crow, Darragh Duffy
Type I interferons (IFNs) are essential mediators of antiviral responses. These cytokines have been implicated in the pathogenesis of autoimmunity, most notably systemic lupus erythematosus (SLE), diabetes mellitus, and dermatomyositis, as well as monogenic type I interferonopathies. Despite a fundamental role in health and disease, the direct quantification of type I IFNs has been challenging. Using single-molecule array (Simoa) digital ELISA technology, we recorded attomolar concentrations of IFNα in healthy donors, viral infection, and complex and monogenic interferonopathies...
May 1, 2017: Journal of Experimental Medicine
https://www.readbyqxmd.com/read/28403725/clock-ticking-again-on-four-hour-target
#3
Nick Evans
Emergency departments (EDs) in England have been told they need to start hitting the four-hour target again by March 2018. Health secretary Jeremy Hunt has set the deadline following the announcement of extra money in the Budget.
April 13, 2017: Emergency Nurse: the Journal of the RCN Accident and Emergency Nursing Association
https://www.readbyqxmd.com/read/28399775/let-s-just-hold-a-real-vote
#4
Gareth Phillips
The planned RCN consultation to gauge how nurses feel about balloting on industrial action is a step in the right direction, but for heaven's sake why don't we just hold a real vote? No one is interested in a test vote - not the media, not members. A real vote would be headline news and RCN members would be enthused and motivated. As it is, we are just kicking the ball into the long grass yet again. There will be a low turnout and we will end up shrugging our shoulders and saying 'There's nothing to be done'...
April 12, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28394764/telomeres-and-the-natural-lifespan-limit-in-humans
#5
Troels Steenstrup, Jeremy D Kark, Simon Verhulst, Mikael Thinggaard, Jacob V B Hjelmborg, Christine Dalgård, Kirsten Ohm Kyvik, Lene Christiansen, Massimo Mangino, Timothy D Spector, Inge Petersen, Masayuki Kimura, Athanase Benetos, Carlos Labat, Ronit Sinnreich, Shih-Jen Hwang, Daniel Levy, Steven C Hunt, Annette L Fitzpatrick, Wei Chen, Gerald S Berenson, Michelangela Barbieri, Giuseppe Paolisso, Shahinaz M Gadalla, Sharon A Savage, Kaare Christensen, Anatoliy I Yashin, Konstantin G Arbeev, Abraham Aviv
An ongoing debate in demography has focused on whether the human lifespan has a maximal natural limit. Taking a mechanistic perspective, and knowing that short telomeres are associated with diminished longevity, we examined whether telomere length dynamics during adult life could set a maximal natural lifespan limit. We define leukocyte telomere length of 5 kb as the 'telomeric brink', which denotes a high risk of imminent death. We show that a subset of adults may reach the telomeric brink within the current life expectancy and more so for a 100-year life expectancy...
April 2017: Aging
https://www.readbyqxmd.com/read/28357949/jeremy-hunt-outlines-his-four-priorities
#6
(no author information available yet)
Senior nurses can help make improvements in four priority areas, the health secretary told the chief nursing officer for England's summit last month.
March 30, 2017: Nursing Management (Harrow)
https://www.readbyqxmd.com/read/28351237/nursingstandard-com
#7
(no author information available yet)
1 Health secretary Jeremy Hunt told the Chief Nursing Officer for England's Summit how he 'dearly' wants to increase nurse pay - but is restricted by limited resources and other pressures on the NHS. Read more: rcni.com/hunt-on-pay.
March 29, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28327036/nurses-deserve-more-but-funds-are-tight-says-hunt
#8
Matthew Mckew
Health secretary Jeremy Hunt says he 'dearly' wants to increase nurse pay, but is restricted by limited resources and other pressures on the NHS.
March 22, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28327017/hunt-has-no-intention-of-giving-nurses-a-pay-rise
#9
Natasha Draper
I'm a senior nurse in the mental health sector, and Jeremy Hunt probably spends more on his monthly lunch allowance than I earn for my annual wage. He doesn't care about us on the front line. He has no intention of giving nurses a pay rise.
March 22, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28327009/nurse-pay-unfair
#10
Sean Brough
Health secretary Jeremy Hunt told delegates at the chief nursing officer for England's summit that he wants to give nurses a pay rise (online news, 15 March).
March 22, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28238262/cell-free-protein-synthesis-approach-to-biosensing-htr%C3%AE-specific-endocrine-disruptors
#11
Amin S M Salehi, Miriam J Shakalli Tang, Mark T Smith, Jeremy M Hunt, Robert A Law, David W Wood, Bradley C Bundy
Here we introduce a Rapid Adaptable Portable In vitro Detection biosensor platform (RAPID) for detecting ligands that interact with nuclear hormone receptors (NHRs). The RAPID platform can be adapted for field use, allowing rapid evaluation of endocrine disrupting chemicals (EDCs) presence or absence in environmental samples, and can also be applied for drug screening. The biosensor is based on an engineered, allosterically activated fusion protein, which contains the ligand binding domain from a target NHR (human thyroid receptor β in this work)...
March 10, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28120683/truth-exposed-in-the-hospital-documentary
#12
Sue Wise Lodge
The Hospital documentary is excellent and upsetting but truthful. Well done to all those involved. I have worked in the NHS for almost 40 years and am exasperated at what's happened to the NHS. I'd like to think Jeremy Hunt is watching the programme, but I am not holding my breath.
January 25, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28045625/ki67-proliferation-index-as-a-tool-for-chemotherapy-decisions-during-and-after-neoadjuvant-aromatase-inhibitor-treatment-of-breast-cancer-results-from-the-american-college-of-surgeons-oncology-group-z1031-trial-alliance
#13
Matthew J Ellis, Vera J Suman, Jeremy Hoog, Rodrigo Goncalves, Souzan Sanati, Chad J Creighton, Katherine DeSchryver, Erika Crouch, Amy Brink, Mark Watson, Jingqin Luo, Yu Tao, Michael Barnes, Mitchell Dowsett, G Thomas Budd, Eric Winer, Paula Silverman, Laura Esserman, Lisa Carey, Cynthia X Ma, Gary Unzeitig, Timothy Pluard, Pat Whitworth, Gildy Babiera, J Michael Guenther, Zoneddy Dayao, David Ota, Marilyn Leitch, John A Olson, D Craig Allred, Kelly Hunt
Purpose To determine the pathologic complete response (pCR) rate in estrogen receptor (ER) -positive primary breast cancer triaged to chemotherapy when the protein encoded by the MKI67 gene (Ki67) level was > 10% after 2 to 4 weeks of neoadjuvant aromatase inhibitor (AI) therapy. A second objective was to examine risk of relapse using the Ki67-based Preoperative Endocrine Prognostic Index (PEPI). Methods The American College of Surgeons Oncology Group (ACOSOG) Z1031A trial enrolled postmenopausal women with stage II or III ER-positive (Allred score, 6 to 8) breast cancer whose treatment was randomly assigned to neoadjuvant AI therapy with anastrozole, exemestane, or letrozole...
April 1, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/27925566/health-secretary-agrees-nursing-associate-role-should-be-regulated-by-the-nmc
#14
(no author information available yet)
Health secretary Jeremy Hunt has conceded the nursing associate role should be subject to professional regulation.
December 7, 2016: Nursing Standard
https://www.readbyqxmd.com/read/27866992/comorbidities-that-cause-pain-and-the-contributors-to-pain-in-individuals-with-chronic-obstructive-pulmonary-disease
#15
Yi-Wen Chen, Pat G Camp, Harvey O Coxson, Jeremy D Road, Jordan A Guenette, Michael A Hunt, W Darlene Reid
OBJECTIVE: To determine comorbidities that cause pain and the potential contributors to pain in individuals with COPD. DESIGN: Prospective cross-sectional survey study. SETTING: Pulmonary rehabilitation programs of six centers. PARTICIPANTS: A convenience sample of individuals with COPD who attended pulmonary rehabilitation programs (n=137). In total, 100 (73%) returned the survey packages. Of those responders, 96 (70%) participants were included in the analyses...
November 17, 2016: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/27802837/comparison-of-carnivore-omnivore-and-herbivore-mammalian-genomes-with-a-new-leopard-assembly
#16
Soonok Kim, Yun Sung Cho, Hak-Min Kim, Oksung Chung, Hyunho Kim, Sungwoong Jho, Hong Seomun, Jeongho Kim, Woo Young Bang, Changmu Kim, Junghwa An, Chang Hwan Bae, Youngjune Bhak, Sungwon Jeon, Hyejun Yoon, Yumi Kim, JeHoon Jun, HyeJin Lee, Suan Cho, Olga Uphyrkina, Aleksey Kostyria, John Goodrich, Dale Miquelle, Melody Roelke, John Lewis, Andrey Yurchenko, Anton Bankevich, Juok Cho, Semin Lee, Jeremy S Edwards, Jessica A Weber, Jo Cook, Sangsoo Kim, Hang Lee, Andrea Manica, Ilbeum Lee, Stephen J O'Brien, Jong Bhak, Joo-Hong Yeo
BACKGROUND: There are three main dietary groups in mammals: carnivores, omnivores, and herbivores. Currently, there is limited comparative genomics insight into the evolution of dietary specializations in mammals. Due to recent advances in sequencing technologies, we were able to perform in-depth whole genome analyses of representatives of these three dietary groups. RESULTS: We investigated the evolution of carnivory by comparing 18 representative genomes from across Mammalia with carnivorous, omnivorous, and herbivorous dietary specializations, focusing on Felidae (domestic cat, tiger, lion, cheetah, and leopard), Hominidae, and Bovidae genomes...
October 11, 2016: Genome Biology
https://www.readbyqxmd.com/read/27646068/g7-health-ministers-kobe-communiqu%C3%A3
#17
Yasuhisa Shiozaki, Jane Philpott, Marisol Touraine, Gottfried Hermann Gröhe, Beatrice Lorenzin, Jeremy Hunt, Sylvia Mathews Burwell, Vytenis Povilas Andriukaitis
No abstract text is available yet for this article.
September 24, 2016: Lancet
https://www.readbyqxmd.com/read/27624501/junior-doctors-high-court-challenge-to-jeremy-hunt
#18
Clare Dyer
No abstract text is available yet for this article.
September 13, 2016: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/27507354/unions-censure-jeremy-hunt-s-rigid-insistence-on-public-sector-pay-restraint
#19
(no author information available yet)
Unions have condemned health secretary Jeremy Hunt's views that pay restraint for nurses and other public sector workers continue.
August 10, 2016: Nursing Standard
https://www.readbyqxmd.com/read/27502118/aromatase-inhibition-remodels-the-clonal-architecture-of-estrogen-receptor-positive-breast-cancers
#20
Christopher A Miller, Yevgeniy Gindin, Charles Lu, Obi L Griffith, Malachi Griffith, Dong Shen, Jeremy Hoog, Tiandao Li, David E Larson, Mark Watson, Sherri R Davies, Kelly Hunt, Vera J Suman, Jacqueline Snider, Thomas Walsh, Graham A Colditz, Katherine DeSchryver, Richard K Wilson, Elaine R Mardis, Matthew J Ellis
Resistance to oestrogen-deprivation therapy is common in oestrogen-receptor-positive (ER+) breast cancer. To better understand the contributions of tumour heterogeneity and evolution to resistance, here we perform comprehensive genomic characterization of 22 primary tumours sampled before and after 4 months of neoadjuvant aromatase inhibitor (NAI) treatment. Comparing whole-genome sequencing of tumour/normal pairs from the two time points, with coincident tumour RNA sequencing, reveals widespread spatial and temporal heterogeneity, with marked remodelling of the clonal landscape in response to NAI...
August 9, 2016: Nature Communications
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