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Jeremy hunt

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https://www.readbyqxmd.com/read/28812510/make-jeremy-hunt-read-ns
#1
Penny Mannings
Jeremy Hunt should be put in a darkened room with a supply of Nursing Standard and - over a 12-hour shift with a snatched toilet break/cup of coffee - forced to read from cover to cover.
August 16, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28801307/loss-of-mutl-disrupts-chk2-dependent-cell-cycle-control-through-cdk4-6-to-promote-intrinsic-endocrine-therapy-resistance-in-primary-breast-cancer
#2
Svasti Haricharan, Nindo Punturi, Purba Singh, Kimberly R Holloway, Meenakshi Anurag, Jacob Schmelz, Cheryl Schmidt, Jonathan T Lei, Vera Suman, Kelly Hunt, John A Olson, Jeremy Hoog, Shunqiang Li, Shixia Huang, Dean P Edwards, Shyam M Kavuri, Matthew N Bainbridge, Cynthia X Ma, Matthew J Ellis
Significant endocrine therapy-resistant tumor proliferation is present in ≥20% of estrogen receptor positive (ER+) primary breast cancers and is associated with disease recurrence and death. Here, we uncover a link between intrinsic endocrine therapy resistance and dysregulation of the MutL mismatch repair complex (MLH1/3, PMS1/2), and demonstrate a direct role for MutL complex loss in resistance to all classes of endocrine therapy. We find that MutL deficiency in ER+ breast cancer abrogates Chk2-mediated inhibition of CDK4, a prerequisite for endocrine therapy responsiveness...
August 11, 2017: Cancer Discovery
https://www.readbyqxmd.com/read/28721782/review-body-reaction
#3
Karen Chilver
Health secretary Jeremy Hunt has pledged to listen to what the pay review body (RB) has to say about the pay cap for nurses. That's all very well, but it is worth remembering that he voted against scrapping the cap in a Commons vote in June. So we won't be holding our breaths for a change of heart.
July 19, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28659074/health-secretary-sympathetic-about-nurses-case-for-pay-rise
#4
Matthew Mckew
Health secretary Jeremy Hunt (pictured) used his address to the NHS Confederation conference last month to announce renewed talks with the RCN over nurses' pay.
June 29, 2017: Nursing Management (Harrow)
https://www.readbyqxmd.com/read/28635486/letter
#5
Jeanmarie Ferrie
I was disappointed to see that Jeremy Hunt had been reappointed as health secretary.
June 21, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28635467/health-secretary-to-meet-with-rcn-over-nurse-pay
#6
Flavia Munn, Matthew Mckew
Health secretary Jeremy Hunt will meet with the RCN to talk about nurses' pay, health leaders at the NHS Confederation conference heard last week.
June 21, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28610518/our-health-secretary-remains-but-his-priorities-must-change
#7
(no author information available yet)
So welcome back, Jeremy Hunt. Many congratulations on your re-appointment, even if the election did not pan out as you had hoped. Your mandate is weak, but your leader is keen to 'get on with the job', so here's what nurses would like you to prioritise over the next 12 months.
June 14, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28593644/efficient-trna-degradation-and-quantification-in-escherichia-coli-cell-extract-using-rnase-coated-magnetic-beads-a-key-step-toward-codon-emancipation
#8
Amin S M Salehi, Mark T Smith, Song-Min Schinn, Jeremy M Hunt, Christina Muhlestein, Joann Diray-Arce, Brent L Nielsen, Bradley C Bundy
Emancipating sense codons toward a minimized genetic code is of significant interest to science and engineering. A key approach toward sense codon emancipation is the targeted in vitro removal of native tRNA. However, challenges remain such as the insufficient depletion of tRNA in lysate-based in vitro systems and the high cost of the purified components system (PURE). Here we used RNase-coated superparamagnetic beads to efficiently degrade E. coli endogenous tRNA. The presented method removes >99% of tRNA in cell lysates, while partially preserving cell-free protein synthesis activity...
June 8, 2017: Biotechnology Progress
https://www.readbyqxmd.com/read/28450346/rachel-clarke-jeremy-hunt-i-m-after-you
#9
(no author information available yet)
No abstract text is available yet for this article.
April 27, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28420733/detection-of-interferon-alpha-protein-reveals-differential-levels-and-cellular-sources-in-disease
#10
Mathieu P Rodero, Jérémie Decalf, Vincent Bondet, David Hunt, Gillian I Rice, Scott Werneke, Sarah L McGlasson, Marie-Alexandra Alyanakian, Brigitte Bader-Meunier, Christine Barnerias, Nathalia Bellon, Alexandre Belot, Christine Bodemer, Tracy A Briggs, Isabelle Desguerre, Marie-Louise Frémond, Marie Hully, Arn M J M van den Maagdenberg, Isabelle Melki, Isabelle Meyts, Lucile Musset, Nadine Pelzer, Pierre Quartier, Gisela M Terwindt, Joanna Wardlaw, Stewart Wiseman, Frédéric Rieux-Laucat, Yoann Rose, Bénédicte Neven, Christina Hertel, Adrian Hayday, Matthew L Albert, Flore Rozenberg, Yanick J Crow, Darragh Duffy
Type I interferons (IFNs) are essential mediators of antiviral responses. These cytokines have been implicated in the pathogenesis of autoimmunity, most notably systemic lupus erythematosus (SLE), diabetes mellitus, and dermatomyositis, as well as monogenic type I interferonopathies. Despite a fundamental role in health and disease, the direct quantification of type I IFNs has been challenging. Using single-molecule array (Simoa) digital ELISA technology, we recorded attomolar concentrations of IFNα in healthy donors, viral infection, and complex and monogenic interferonopathies...
May 1, 2017: Journal of Experimental Medicine
https://www.readbyqxmd.com/read/28403725/clock-ticking-again-on-four-hour-target
#11
Nick Evans
Emergency departments (EDs) in England have been told they need to start hitting the four-hour target again by March 2018. Health secretary Jeremy Hunt has set the deadline following the announcement of extra money in the Budget.
April 13, 2017: Emergency Nurse: the Journal of the RCN Accident and Emergency Nursing Association
https://www.readbyqxmd.com/read/28399775/let-s-just-hold-a-real-vote
#12
Gareth Phillips
The planned RCN consultation to gauge how nurses feel about balloting on industrial action is a step in the right direction, but for heaven's sake why don't we just hold a real vote? No one is interested in a test vote - not the media, not members. A real vote would be headline news and RCN members would be enthused and motivated. As it is, we are just kicking the ball into the long grass yet again. There will be a low turnout and we will end up shrugging our shoulders and saying 'There's nothing to be done'...
April 12, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28394764/telomeres-and-the-natural-lifespan-limit-in-humans
#13
Troels Steenstrup, Jeremy D Kark, Simon Verhulst, Mikael Thinggaard, Jacob V B Hjelmborg, Christine Dalgård, Kirsten Ohm Kyvik, Lene Christiansen, Massimo Mangino, Timothy D Spector, Inge Petersen, Masayuki Kimura, Athanase Benetos, Carlos Labat, Ronit Sinnreich, Shih-Jen Hwang, Daniel Levy, Steven C Hunt, Annette L Fitzpatrick, Wei Chen, Gerald S Berenson, Michelangela Barbieri, Giuseppe Paolisso, Shahinaz M Gadalla, Sharon A Savage, Kaare Christensen, Anatoliy I Yashin, Konstantin G Arbeev, Abraham Aviv
An ongoing debate in demography has focused on whether the human lifespan has a maximal natural limit. Taking a mechanistic perspective, and knowing that short telomeres are associated with diminished longevity, we examined whether telomere length dynamics during adult life could set a maximal natural lifespan limit. We define leukocyte telomere length of 5 kb as the 'telomeric brink', which denotes a high risk of imminent death. We show that a subset of adults may reach the telomeric brink within the current life expectancy and more so for a 100-year life expectancy...
April 2017: Aging
https://www.readbyqxmd.com/read/28357949/jeremy-hunt-outlines-his-four-priorities
#14
(no author information available yet)
Senior nurses can help make improvements in four priority areas, the health secretary told the chief nursing officer for England's summit last month.
March 30, 2017: Nursing Management (Harrow)
https://www.readbyqxmd.com/read/28351237/nursingstandard-com
#15
(no author information available yet)
1 Health secretary Jeremy Hunt told the Chief Nursing Officer for England's Summit how he 'dearly' wants to increase nurse pay - but is restricted by limited resources and other pressures on the NHS. Read more: rcni.com/hunt-on-pay.
March 29, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28327036/nurses-deserve-more-but-funds-are-tight-says-hunt
#16
Matthew Mckew
Health secretary Jeremy Hunt says he 'dearly' wants to increase nurse pay, but is restricted by limited resources and other pressures on the NHS.
March 22, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28327017/hunt-has-no-intention-of-giving-nurses-a-pay-rise
#17
Natasha Draper
I'm a senior nurse in the mental health sector, and Jeremy Hunt probably spends more on his monthly lunch allowance than I earn for my annual wage. He doesn't care about us on the front line. He has no intention of giving nurses a pay rise.
March 22, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28327009/nurse-pay-unfair
#18
Sean Brough
Health secretary Jeremy Hunt told delegates at the chief nursing officer for England's summit that he wants to give nurses a pay rise (online news, 15 March).
March 22, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28238262/cell-free-protein-synthesis-approach-to-biosensing-htr%C3%AE-specific-endocrine-disruptors
#19
Amin S M Salehi, Miriam J Shakalli Tang, Mark T Smith, Jeremy M Hunt, Robert A Law, David W Wood, Bradley C Bundy
Here we introduce a Rapid Adaptable Portable In vitro Detection biosensor platform (RAPID) for detecting ligands that interact with nuclear hormone receptors (NHRs). The RAPID platform can be adapted for field use, allowing rapid evaluation of endocrine disrupting chemicals (EDCs) presence or absence in environmental samples, and can also be applied for drug screening. The biosensor is based on an engineered, allosterically activated fusion protein, which contains the ligand binding domain from a target NHR (human thyroid receptor β in this work)...
March 10, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28120683/truth-exposed-in-the-hospital-documentary
#20
Sue Wise Lodge
The Hospital documentary is excellent and upsetting but truthful. Well done to all those involved. I have worked in the NHS for almost 40 years and am exasperated at what's happened to the NHS. I'd like to think Jeremy Hunt is watching the programme, but I am not holding my breath.
January 25, 2017: Nursing Standard
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