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"dyshidrotic eczema"

Gillian K Weston, Jette Hooper, Bruce E Strober
Dupilumab (Dupixent, Regeneron Pharmaceuticals and Sanofi Genzyme) is a novel biologic medication recently approved by the FDA for the treatment of moderate-to-severe atopic dermatitis in adults who have not achieved adequate control with topical medications. Dyshidrotic eczema is a distinct entity, often considered on the spectrum of atopic dermatitis, that primarily effects the palms and soles; it is often associated with considerable morbidity yet is frequently challenging to treat. We report two cases of recalcitrant dyshidrotic eczema treated successfully with dupilumab at standard dosing...
March 1, 2018: Journal of Drugs in Dermatology: JDD
José-María Ortiz-Salvador, Altea Esteve-Martínez, Ana García-Rabasco, Daniela Subiabre-Ferrer, Lorena Martínez-Leboráns, Violeta Zaragoza-Ninet
BACKGROUND/OBJECTIVES: Footwear dermatitis is a form of contact dermatitis resulting from exposure to shoes. There have been only small studies regarding foot contact dermatitis in children. The present study was undertaken to define the prevalence and epidemiologic and clinical features of shoe dermatitis in children. METHODS: A retrospective study was undertaken of all children referred for patch testing between 1996 and 2015. Children with dermatitis limited to the feet were selected...
September 2017: Pediatric Dermatology
Aya Nishizawa
Dyshidrotic eczema, also known as dyshidrotic dermatitis or pompholyx, is characterized by pruritic, small tense vesicles mainly on the palmoplantar region and lateral and ventral surfaces of the fingers. While its etiology appears to be related to sweating, as dyshidrotic eczema often occurs in an individual with hyperhidrosis, and the spring allergy season, histologic examination shows an eczematous reaction around the sweat ducts which is not associated with abnormalities of the sweat ducts. More recently, the nomenclature of 'acute and recurrent vesicular hand dermatitis' has been proposed to reflect clinical features of dyshidrotic eczema...
2016: Current Problems in Dermatology
Angelo Landriscina, Tagai Musaev, Bijal Amin, Adam J Friedman
An acute inflammatory nodule of unknown etiology can pose a formidable diagnostic challenge. Here, we highlight the importance of including Mycobacterium avium intracellulare complex (MAC) and other atypical mycobacterial infections in the differential diagnosis of a cutaneous nodule in an immunocompetent individual. We also explore the implications of eczema in the development of a mycobacterial infectious process. We report a case of MAC skin infection in an immunocompetent individual. The patient is a 49-year-old male with a history of dyshidrotic eczema presenting with a fluctuant, non-draining nodule on his right forearm for 2 to 3 weeks, identified by tissue DNA probe to be a cutaneous MAC infection without systemic complications, as serologies and chest X-ray were unremarkable...
December 2014: Journal of Drugs in Dermatology: JDD
Vasiliki Markantoni, Anargyros Kouris, Kalliopi Armyra, Charitomeni Vavouli, George Kontochristopoulos
Dyshidrotic hand eczema is a common condition, which can be resistant to various treatments. Although a number of etiologic factors are involved in the pathogenesis of dyshidrotic eczema, hyperhidrosis is assumed to play a significant role. Oxybutynin is an alternative treatment for hyperhidrosis. We present the cases of two patients suffering from hyperhidrosis and dyshidrotic eczema, who were treated with oxybutynin with impressive results.
November 2014: Dermatologic Therapy
Dilcan Kotan, Teoman Erdem, Bilgehan Atilgan Acar, Ayhan Boluk
Intravenous immunoglobulin (IVIg) treatment is highly effective for autoimmune diseases including myasthenia gravis. Recovery is observed at approximately. 75% of myasthenia gravis patients through IVIg treatment. As a result of many clinical studies, the recommended dose is determined as 0.4 g/kg for 5 days (maximum total dose at 2 g/kg body weight). If an additional immunomodulatory treatment is not administered, IVIg maintenance treatment is needed mostly. However, some side effects may inhibit long-term treatment...
2013: BMJ Case Reports
Kachiu C Lee, Barry Ladizinski
No abstract text is available yet for this article.
August 6, 2013: CMAJ: Canadian Medical Association Journal, Journal de L'Association Medicale Canadienne
Marie Louise A Schuttelaar, Pieter Jan Coenraads, Janneke Huizinga, Jan G De Monchy, Karin M Vermeulen
BACKGROUND: It is unclear whether the respiratory tract is involved in eliciting or aggravating eczematous lesions in patients with vesicular hand eczema. Objectives. To investigate the effect of inhalation of house dust mite (HDM) on vesicular hand eczema. METHODS: Eighteen patients with vesicular hand eczema and HDM allergy received inhalation challenges with four concentrations of HDM in a randomized, double-blind, placebo-controlled, cross-over study. Early asthmatic reactions and late asthmatic reactions were defined as a placebo-corrected fall of 15% or more from baseline of forced expiratory volume in 1 second...
February 2013: Contact Dermatitis
Y Y Chang, J van der Velden, G van der Wier, D Kramer, G F H Diercks, M van Geel, P J Coenraads, P L J M Zeeuwen, M F Jonkman
BACKGROUND: Keratolysis exfoliativa (KE), also known as dyshidrosis lamellosa sicca, is a palmoplantar dermatosis characterized by air-filled blisters and collarette desquamation. It has been regarded as a subtype of dyshidrotic eczema, a fungal infection or a dermatophytid reaction. KE may also resemble acral peeling skin syndrome and localized epidermolysis bullosa simplex. Although KE is a common disorder, it is a rarely reported and is an under-recognized dermatosis. OBJECTIVES: To delineate the characteristic features of KE...
November 2012: British Journal of Dermatology
Afsaneh Alavi, Sandra Skotnicki, Gordon Sussman, R Gary Sibbald
PURPOSE: To enhance the learner's competence with knowledge of hand dermatitis. TARGET AUDIENCE: : This continuing education activity is intended for physicians and nurses with an interest in skin and wound care. OBJECTIVES: After participating in this educational activity, the participant should be better able to: 1. Demonstrate knowledge of the pathophysiology and assessment of, and diagnostic testing for, hand dermatitis. 2. Apply knowledge of hand dermatitis to patient care scenarios for treatment recommendations and patient education...
August 2012: Advances in Skin & Wound Care
Agnes Bretterklieber, Franz J Legat, Peter Wolf, Angelika Hofer
BACKGROUND: Numerous studies have confirmed the short-term effectiveness of 8-methoxypsoralen bath PUVA therapy in patients with chronic palmoplantar dermatoses; however, little is known about long-term results. PATIENTS AND METHODS: In this retrospective study we examined the long-term results in 79 patients (mean age: 48 years) with chronic palmoplantar dermatoses who were treated with bath PUVA three times a week over an 8-year period. A good clinical response (a reduction of more than 50% of the skin lesions) occurred after a mean of 23 treatments and a mean cumulative UVA dose of 39 J/cm(2) in 51 patients (65%)...
November 2012: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
Ana Maria Abreu-Velez, Frank J Pinto, Michael S Howard
CONTEXT: Pompholyx (called dyshidrosis by some) is one of the most common conditions and its immune response is presently poorly understood. CASE REPORT: We describe a 58 year old African American female with a clinical history of rheumatoid arthritis and type II diabetes who presented a chronic five-year, itchy vesicular/blistering rash involving her hands and feet. A lesional skin biopsy was taken for hematoxylin and eosin (H & E) analysis. In addition, a multicolor direct immunofluorescence (MDIF) and immunohistochemistry (IHC) studies were performed...
August 2009: North American Journal of Medical Sciences
Takahisa Shiraishi, Toshiyuki Yamamoto
Dyshidrotic eczema is one of the rare cutaneous adverse effects of intravenous immunoglobulin therapy, usually seen in adults. We herein report the first pediatric case of severe dyshidrotic eczema occurring after intravenous immunoglobulin therapy for Kawasaki syndrome.
May 2013: Pediatric Dermatology
K Brandt, K Schäkel, F Stölzel, J Janschek, G Ehninger, M Schaich
Cytarabine is an effective drug in the treatment of haematological malignancies. The therapy is associated with various complications. Frequencies of dermatological side-effects range from 2-72% and occur most commonly after high-dose regimens. Although most cutaneous reactions are mild and resolve spontaneously within several days, they may result in an increased risk of infection and alterations in comfort. In some cases, severe life-threatening reactions have been reported. Here we describe the case of a patient with acute myeloid leukaemia, who developed severe exceptional skin toxicity in terms of auricular oedema and palmar dyshidrotic eczema after the application of low-dose cytarabine...
October 4, 2010: Case Reports in Oncology
Miguel A Ruiz, Felipe Heras, Agusti Alomar, Luis Conde-Salazar, Jesús de la Cuadra, Esther Serra, Francisco Regalado, Ralf Halbach
OBJECTIVE: To develop a self-administered short questionnaire to assess patient satisfaction with medical treatment for hand eczema (dermatitis) with good psychometric properties. METHOD: The content of the questionnaire was determined on the basis of clinical consultation with groups of patients, from studying the existing instruments, and from discussions with a panel of seven experts. A first draft version containing 38 items organised in six dimensions was tested on a pilot sample of patients to assess its legibility...
November 5, 2010: Health and Quality of Life Outcomes
Niels K Veien
The terminology of eruptive, symmetric, vesicular, and/or bullous dermatitis on the palms and/or palmar aspects or sides of the fingers includes the terms pompholyx, dyshidrosis, and dyshidrotic eczema. This article presents the case for a standard, broad definition of this condition and reviews the epidemiology, clinical features, etiology, and treatment of acute and recurrent vesicular hand dermatitis with special emphasis on endogenous causes.
July 2009: Dermatologic Clinics
Milorad Letić
Manifestations of dyshidrotic eczema can be alleviated by exposure to medium and high doses of ultraviolet A1 (UVA1) radiation. Since the induction of apoptosis of T cells by UVA1, as the basic mechanism of therapy, is proportional to the dose of radiation it is to be expected that in mild cases or for maintenance therapy low doses of radiation will also be effective. UVA1 radiation is a constituent of sunlight, so exposure to sunlight could prove beneficial in treating dyshidrotic eczema.
August 2009: Medical Hypotheses
Stanislava Tzaneva, Harald Kittler, Christiane Thallinger, Herbert Hönigsmann, Adrian Tanew
BACKGROUND: Both oral and bath PUVA with 8-methoxypsoralen (8-MOP) have been shown to be effective in the treatment of chronic palmoplantar eczema. However, most studies were retrospective and did not include longer follow-up periods. AIM: To compare the therapeutic efficacy, tolerability and duration of remission after oral vs. bath PUVA using 8-MOP in patients with chronic palmoplantar eczema. METHODS: Twenty-nine patients were randomly allocated to treatment with oral or bath PUVA...
April 2009: Photodermatology, Photoimmunology & Photomedicine
Joseph Stuckert, Susan Nedorost
BACKGROUND: Dyshidrotic eczema is a type of chronic intermittent dermatitis characterized by vesicles, dystrophic fingernail changes, and rarely bullae that affects the hands and feet. Many exogenous factors may trigger a flare including dermatophyte infections, contact irritants, and metal hypersensitivity. Although metal hypersensitivity does not play a role in all cases of dyshidrotic eczema, high oral ingestion of nickel and/or cobalt should be considered, regardless of patch test results...
December 2008: Contact Dermatitis
Emine Tamer, Mustafa N Ilhan, Muhterem Polat, Nurdan Lenk, Nuran Alli
The pediatric population is composed of persons under 16 years of age, and few studies are available on the dermatological diseases of this group. In the present study, data on a total of 6300 pediatric patients admitted between the years 2004-2006 were analyzed. Hospital-based patient registry records were used for data collection. The data were analyzed according to age, sex and time of admittance. A female preponderance (53%) was observed, and adolescents (12-16 years old) constituted the largest group within the patient population (47...
July 2008: Journal of Dermatology
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