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Meta-analysis otolaryngology

Sirshak Dutta, Kaustuv Das Biswas, Soumya Ghatak, Dibakar Haldar, Indranil Sen, Ramanuj Sinha
Primary laryngeal carcinoma is a common cancer, predominantly affecting males. Hypothyroidism is an undesirable sequela of both surgery and radiotherapy, the two most commonly used modalities of treatment. For advanced cases, standard treatment protocol includes total laryngectomy and neck dissection along with pre- or postoperative radiotherapy. Hemithyroidectomy is also routinely performed as an integral part of total laryngectomy. In the present study, assessment of the function of the remaining half of the thyroid gland has been done in cases of total laryngectomies in combination with uni- or bilateral neck dissection and pre- or postoperative radiotherapy...
August 2016: Ear, Nose, & Throat Journal
Steve Langton, Derrick Siau, Clare Bankhead
The fast-track system in the UK for patients with suspected cancer--the two-week rule--states that if cancer is suspected there should be a maximum of 14 days between referral from primary care and consultation with a specialist. This approach is valued by patients, ensures a universal standard of diagnosis, and speeds up the overall management of cancer. However, some say that the rule has had little or no effect on survival, results in a diagnosis of cancer in only a small proportion of patients referred, and is expensive...
February 2016: British Journal of Oral & Maxillofacial Surgery
J Hendry, A Chin, I R C Swan, M A Akeroyd, G G Browning
BACKGROUND: The Glasgow Benefit Inventory (GBI) is a validated, generic patient-recorded outcome measure widely used in otolaryngology to report change in quality of life post-intervention. OBJECTIVES OF REVIEW: To date, no systematic review has made (i) a quality assessment of reporting of Glasgow Benefit Inventory outcomes; (ii) a comparison between Glasgow Benefit Inventory outcomes for different interventions and objectives; (iii) an evaluation of subscales in describing the area of benefit; (iv) commented on its value in clinical practice and research...
June 2016: Clinical Otolaryngology
Sumanth Kumbargere Nagraj, Shetty Naresh, Kandula Srinivas, P Renjith George, Ashish Shrestha, David Levenson, Debra M Ferraiolo
BACKGROUND: The sense of taste is very much essential to the overall health of the individual. It is a necessary component to enjoying one's food, which in turn provides nutrition to an individual. Any disturbance in taste perception can hamper the quality of life in such patients by influencing their appetite, body weight and psychological well-being. Taste disorders have been treated using different modalities of treatment and there is no consensus for the best intervention. Hence this Cochrane systematic review was undertaken...
2014: Cochrane Database of Systematic Reviews
Syed F Ahsan, Robert Standring, Yun Wang
OBJECTIVES/HYPOTHESIS: To perform a systematic review and meta-analysis of micropressure treatment for Meniere's disease (MD). DATA SOURCES: Medline, Ovid, Web of Science, and Cochrane Library search of the literature from January 1996 to December 2012. REVIEW METHODS: Systematic literature review followed Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Inclusion criteria required definitive diagnosis of unilateral MD, treatment with Meniett device, vertigo control results, and hearing results before and after treatment...
January 2015: Laryngoscope
Luke Rudmik, Timothy L Smith
OBJECTIVE: This study aimed to evaluate the cost-effectiveness of a mometasone steroid-eluting sinus implant compared to a nonsteroid-eluting sinus implant following endoscopic sinus surgery (ESS) for chronic rhinosinusitis. STUDY DESIGN: Economic evaluation using a decision tree model. SETTING: Academic and nonacademic otolaryngology practices. SUBJECTS: Patients with refractory chronic rhinosinusitis undergoing ESS...
August 2014: Otolaryngology—Head and Neck Surgery
Amit Justin Sood, Paul R Lambert, Shaun A Nguyen, Ted A Meyer
OBJECTIVE: To analyze current endolymphatic surgery techniques and quantify their efficacy in controlling vertigo and maintaining hearing in the short and long term. DATA SOURCES: A comprehensive literature search using the PubMed-NCBI database from 1970 to 2013. STUDY SELECTION: Articles on sac decompression and mastoid shunt (with and without silastic) were included. Included studies had to report data using the 1985 or 1995 American Academy of Otolaryngology-Head and Neck Foundation (AAO-HNS) guidelines, describe surgical technique in detail, include a minimum of 10 patients, and have minimum 12 months of follow-up...
July 2014: Otology & Neurotology
Robert L Folmer, Sarah M Theodoroff, William Hal Martin, Yongbing Shi
BACKGROUND: Because chronic tinnitus is a condition that negatively impacts the quality of life of millions of people worldwide, a safe and effective treatment for tinnitus has been sought for millennia. However, effective treatments for tinnitus are greatly outnumbered by ineffective strategies, medications, devices, and surgeries that continue to be developed and promoted for the condition. PURPOSE: This article describes and critiques experimental, controversial, and potential treatments for chronic tinnitus...
January 2014: Journal of the American Academy of Audiology
Ravindhra G Elluru, Jose M Contreras, David M Albert
PURPOSE OF REVIEW: Children with epidermolysis bullosa can present with disease(s) of the ears, nose, and throat, often related directly to the pathophysiology of their epidermolysis bullosa. Otolaryngologic diseases in children with epidermolysis bullosa have to be managed having a proper understanding of the diagnosis and pathophysiology of epidermolysis bullosa. The purpose of this review is to describe the current nomenclature and diagnostic algorithms for epidermolysis bullosa, and methods for the management of cutaneous and mucosal lesions...
December 2013: Current Opinion in Otolaryngology & Head and Neck Surgery
F Marchal
Once more, this selection of papers is intended towards the general practionner, avoiding deliberately technical papers. Last year, we focused on rhinology and head and neck surgery, and this year we choose other themes, like dysphonia, gastroesophagal reflux, robotic surgery or interest of PET in thyroid screening. Several meta-analysis are presented, regarding long term antibiotic treatments in case of chronic otitis media, tonsillotomy versus tonsillectomy, MRSA prevalence, or sudden hearing loss.
January 16, 2013: Revue Médicale Suisse
Chee Ching Chan, Yee Yin Chan, Faiz Tanweer
Post-tonsillectomy haemorrhage is a serious complication that can lead to death despite the fact that tonsillectomy is one of the commonest procedures performed in otolaryngology. Post-operative haemorrhage can be reduced by a potent antifibrinolytic agent such as tranexamic acid (TXA). This systematic review aims to evaluate the role of TXA in tonsillectomy. Searches were performed on MEDLINE, EMBASE, Web of Science and the Cochrane Library. Study selection, data extraction and quality assessment were conducted independently by two reviewers...
February 2013: European Archives of Oto-rhino-laryngology
Richard K Gurgel, Robert K Jackler, Robert A Dobie, Gerald R Popelka
The lack of an adequate standardized method for reporting level of hearing function in clinical trials has hampered the ability of investigators to draw comparisons across studies. Variability in data reported and presentation format inhibits meta-analysis and makes it impossible to accumulate the large patient cohorts needed for statistically significant inference. Recognizing its importance to the field and after a widely inclusive discussion, the Hearing Committee of the American Academy of Otolaryngology-Head and Neck Surgery endorsed a new minimal standard for reporting hearing results in clinical trials, consisting of a scattergram relating average pure-tone threshold to word recognition score...
November 2012: Otolaryngology—Head and Neck Surgery
Tammy Hoffmann, Chrissy Erueti, Sarah Thorning, Paul Glasziou
OBJECTIVE: To estimate the degree of scatter of reports of randomised trials and systematic reviews, and how the scatter differs among medical specialties and subspecialties. DESIGN: Cross sectional analysis. DATA SOURCE: PubMed for all disease relevant randomised trials and systematic reviews published in 2009. STUDY SELECTION: Randomised trials and systematic reviews of the nine diseases or disorders with the highest burden of disease, and the broader category of disease to which each belonged...
2012: BMJ: British Medical Journal
Peta-Lee Sacks, Richard J Harvey, Janet Rimmer, Richard M Gallagher, Raymond Sacks
BACKGROUND: Chronic rhinosinusitis (CRS) is an inflammatory disorder of the nose and sinuses. Because fungi were postulated as a potential cause of CRS in the late 1990s, contrasting articles have advocated and refuted the use of antifungal agents in its management. Although good research shows an interaction of the immune system with fungus in CRS, e.g., allergic fungal sinusitis (AFS), this does not imply that fungi are the cause of CRS or that antifungals will be effective in management...
March 2012: American Journal of Rhinology & Allergy
Deepa Bhargava, Kamlesh Bhargava, Ahmed Al-Abri, Wameedh Al-Bassam, Rashid Al-Abri
OBJECTIVES: Although Nasal symptoms induced by Non-allergic rhinitis| (NAR) are a cause of wide spread morbidity; the disease is trivialized. There is a lack of Epidemiological studies on the prevalence of non-allergic rhinitis. In spite of being one of the commonest conditions presenting to the General practitioner and otolaryngologists, the clinical profile, diagnosis, and management outcomes are unknown. The objectives of the study were to examine the prevalence and clinical profile of non-allergic rhinitis in Oman...
November 2011: Oman Medical Journal
Yan Feng, Binquan Wang, Shuxin Wen
BACKGROUND: Laser surgery and radiotherapy are commonly used to treat glottic cancer. OBJECTIVE OF REVIEW: To compare outcomes and cost of laser surgery versus radiotherapy for T1-T2N0 glottic cancer. TYPE OF REVIEW: Meta-analysis. SEARCH STRATEGY: The Cochrane Central Register of Controlled Trials, Ovid MEDLINE® In-Process & Other Non-Indexed Citations, Embase, Web of Science (1990-2010) were searched electronically...
2011: ORL; Journal for Oto-rhino-laryngology and its related Specialties
Raphael Richard Ciuman
Phytotherapeutic pharmaceuticals and herbal medicinal products with its roots in classical phytotherapeutic medicine have a well-established role in otolaryngological therapy, especially for diseases of the upper airways and acute and chronic infections. A thorough selection and application could mean huge benefit for the patient, in particular in cases with contraindications, chemo- and antibiotic resistance or patient request. Besides, it might spare other medications. Phytotherapeutic pharmaceuticals must fulfil the same criteria of quality, effectiveness and harmlessness of evidence-based medicine like chemical pharmaceuticals, although they are often prescribed due to its well established or traditional based use...
February 2012: European Archives of Oto-rhino-laryngology
Peta-Lee Sacks, Richard J Harvey, Janet Rimmer, Richard M Gallagher, Raymond Sacks
BACKGROUND: Chronic rhinosinusitis (CRS) is an inflammatory disorder of the nose and sinuses. Since fungi were postulated as a potential cause of CRS in the late 1990s, there has been increasing controversy about the use of both topical and systemic antifungal agents in its management. Although interaction between the immune system and fungus has been demonstrated in CRS, this does not necessarily imply that fungi are the cause of CRS or that antifungals will be effective its management...
2011: Cochrane Database of Systematic Reviews
Vincent Van Rompaey, Gerd Claes, Jorn Potvin, Kristien Wouters, Paul H Van de Heyning
OBJECTIVE: To perform a systematic review of observational studies reporting hearing outcome in primary stapes surgery where a heat-crimping prosthesis was used. DATA SOURCES: Medline, Cochrane Database of Systematic Reviews, Cochrane Central Register of Controlled Trials, TRIP database, Clinical Trials Registry, ISI Web of Knowledge, and Web of Science. The search was performed on January 1, 2010, including articles published ahead of print. No language restrictions...
April 2011: Otology & Neurotology
Andrew Dias, P Casserly, J E Fenton
The study of errors in medicine has proliferated since the publication of The Institute of Medicine Report 'TO ERR IS HUMAN' in 2000. Case nuances and process of care issues are valuable areas to explore if the goal is to provide the health care worker with the knowledge to avoid future errors. Meta-analysis and randomized controlled trials provide a large data base of evidence towards improvement and opportunities, but it is suggested that case reports can still provide valuable clinical information. The aim is to use the published literature to produce a series of rare harm case reports in E...
September 2010: European Archives of Oto-rhino-laryngology
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