Read by QxMD icon Read


Josie Nott, Aspen Mcintosh, Clare Taube, Mark Taylor
OBJECTIVES: Shared decision-making (SDM) is promoted as beneficial in mental healthcare, despite a dearth of supportive evidence. We aimed to obtain patients' perspective on SDM in a 'real world' hospital sample. METHODS: Structured validated questionnaires were used to examine SDM with regard to treatment choices, and whether SDM influences attitudes towards treatment. The Mini-Mental State Examination was used to assess decision-making capacity. RESULTS: A total of 109 individuals participated, with 60% reporting experiencing SDM...
February 1, 2018: Australasian Psychiatry: Bulletin of Royal Australian and New Zealand College of Psychiatrists
Ajay Kumar Jain, Carel W le Roux, Puneet Puri, Ali Tavakkoli, Nana Gletsu-Miller, Blandine Laferrère, Richard Kellermayer, John K DiBaise, Robert G Martindale, Bruce M Wolfe
The goal of the National Institutes of Health-funded American Society for Parenteral and Enteral Nutrition 2017 research workshop (RW) "Gastric Bypass: Role of the Gut" was to focus on the exciting research evaluating gut-derived signals in modulating outcomes after bariatric surgery. Although gastric bypass surgery has undoubted positive effects, the mechanistic basis of improved outcomes cannot be solely explained by caloric restriction. Emerging data suggest that bile acid metabolic pathways, luminal contents, energy balance, gut mucosal integrity, as well as the gut microbiota are significantly modulated after bariatric surgery and may be responsible for the variable outcomes, each of which was rigorously evaluated...
February 2018: JPEN. Journal of Parenteral and Enteral Nutrition
Diana Ciolacu, Georgeta Cazacu
The development of various green materials from lignin, which is most often considered as waste, is of prime interest from environmental and economic points of view. In the last years, only few studies regarding the use of lignin as a backbone component in the hydrogels have been made. The potential efficacy of lignin in hydrogels with particular emphasis on synthesis and characterization was investigated. By using steam explosion lignin from aspen wood or the corresponding epoxy-resin mixed with poly(vinyl alcohol), a series of new green hydrogels were prepared by covalent crosslinking in the presence of the epichlorohydrin...
April 1, 2018: Journal of Nanoscience and Nanotechnology
Emilie Aubry, Carla Aeberhard, Lia Bally, Jean-Marc Nuoffer, Lorenz Risch, Stefan Mühlebach, Jean-Marc Burgunder, Zeno Stanga
OBJECTIVES: Patients with mitochondrial disorders (MD) frequently present with gastrointestinal complaints, mainly gastrointestinal dysmotility, that interfere with their food intake. A deterioration of their nutritional state may worsen the course of the disease. Our study aimed to evaluate a simple screening tool to identify nutritional risk and perform an extended nutritional assessment to explore the potential presence of deficiencies in this population compared with controls. METHODS: A prospective cohort study was conducted to compare outpatients with MD to matched healthy controls...
March 2018: Nutrition
Guiyan Zang, Sharma Tejasvi, Albert Ratner, Electo Silva Lora
The Biomass Integrated Gasification Combined Cycle (BIGCC) power system is believed to potentially be a highly efficient way to utilize biomass to generate power. However, there is no comparative study of BIGCC systems that examines all the latest improvements for gasification agents, gas turbine combustion methods, and CO2 Capture and Storage options. This study examines the impact of recent advancements on BIGCC performance through exergy analysis using Aspen Plus. Results show that the exergy efficiency of these systems is ranged from 22...
February 2, 2018: Bioresource Technology
Franck Stefani, Nathalie Isabel, Marie-Josée Morency, Manuel Lamothe, Simon Nadeau, Denis Lachance, Edith H Y Li, Charles Greer, Étienne Yergeau, Bradley D Pinno, Armand Séguin
The objective of this study was to investigate the impact of different soil covers used to reclaim decommissioned oil sands mining sites on the genetic diversity of aspen and their associated belowground microbiota. Aspen genotyping showed that trees mostly originated from sexual reproduction on sites reclaimed with soil covers made of upland forest floor-mineral mix (FFMM) and lowland peat-mineral mix (PMM). In contrast, most individuals in mature and burned stands sampled as benchmarks for natural disturbances originated from vegetative reproduction...
February 9, 2018: Scientific Reports
Gregorius Rionugroho Harvianto, Junaid Haider, Jimin Hong, Nguyen Van Duc Long, Jae-Jin Shim, Moo Hwan Cho, Woo Kyoung Kim, Moonyong Lee
Background: 2,3-Butanediol (2,3-BDO) is a synthetic chemical compound that also can be produced by biomass fermentation, which is gaining share in the global market as an intermediate product for numerous applications, i.e. as liquid fuel or fuel additive. Several metabolic engineering fermentation strategies to enhance the production of 2,3-BDO were developed. However, the recovery of 2,3-BDO from its fermentation broth remains a challenge due to its low concentration and its solubility in water and other components...
2018: Biotechnology for Biofuels
Linbo Yan, Yang Cao, Xuezheng Li, Boshu He
A one-dimensional model is built based on the commercial Aspen Plus software to kinetically simulate the biomass/coal co-gasification process in a dual fluidized bed gasifier. The synergistic effect on the co-gasification kinetics is allowed for, and is coupled with the gas-solid flow hydrodynamics. With the developed model, the effects of different key operating parameters including the biomass blending ratio (Rb), the initial bed temperature (Tg), the feedstock mass flow rate (Ffs), the bed material flux (Fbm) and the steam to carbon ratio (Rsc) on the resultant syngas composition and the supplemental fuel mass flow rate (Fsf) are investigated, and the operation parameters are optimized...
February 1, 2018: Bioresource Technology
Thierry Allario, Aude Tixier, Hosam Awad, Cedric Lemaire, Nicole Brunel, Eric Badel, Têtè Sévérien Barigah, Jean-Louis Julien, Pierre Peyret, Ewa J Mellerowicz, Herve Cochard, Stephane Herbette
While the xylem hydraulic properties, such as vulnerability to cavitation (VC), are of paramount importance in drought resistance, their genetic determinants remain unexplored. There is evidence that pectins and their methylation pattern are involved, but the detail of their involvement and the corresponding genes need to be clarified. We analysed the hydraulic properties of the 35S::PME1 transgenic aspen that ectopically under- or over-express a xylem-abundant pectin methyl esterase, PtxtPME1. We also produced and analyzed 4CL1::PGII transgenic poplars expressing a fungal polygalacturonase, AnPGII, under the control of the Ptxa4CL1 promoter that is active in the developing xylem after xylem cell expansion...
February 7, 2018: Physiologia Plantarum
Dolores Sánchez-Rodríguez, Ester Marco, Natalia Ronquillo-Moreno, Liev Maciel-Bravo, Abel Gonzales-Carhuancho, Xavier Duran, Anna Guillén-Solà, Olga Vázquez-Ibar, Ferran Escalada, Josep M Muniesa
BACKGROUND: The aim of this study was to assess the prevalence of malnutrition by applying the ASPEN/AND definition and the ESPEN consensus definition in a postacute-care population, and secondly, to determine the metrological properties of the set of six clinical characteristics that constitute the ASPEN/AND basic diagnosis, compared to the ESPEN consensus, based mostly on objective anthropometric measurements. METHODS: Prospective study of 84 consecutive deconditioned older inpatients (85...
January 25, 2018: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
Aspen R Clements, Brandon Berk, Ilsa R Cooke, Robin T Garrod
Dust grains in cold, dense interstellar clouds build up appreciable ice mantles through the accretion and subsequent surface chemistry of atoms and molecules from the gas. These mantles, of thicknesses on the order of 100 monolayers, are primarily composed of H2O, CO, and CO2. Laboratory experiments using interstellar ice analogues have shown that porosity could be present and can facilitate diffusion of molecules along the inner pore surfaces. However, the movement of molecules within and upon the ice is poorly described by current chemical kinetics models, making it difficult either to reproduce the formation of experimental porous ice structures or to extrapolate generalized laboratory results to interstellar conditions...
February 1, 2018: Physical Chemistry Chemical Physics: PCCP
Lauren Hudson, Jesse Chittams, Cody Griffith, Charlene Compher
BACKGROUND: Few studies have compared malnutrition identified by the Academy of Nutrition and Dietetics/American Society for Parenteral and Enteral Nutrition (AND/ASPEN) consensus criteria with clinical outcomes. Our goal was to compare 30-day readmissions (primary outcome), hospital mortality, length of stay (LOS) in survivors, and time to discharge alive (TDA) in all patients assessed as malnourished or not malnourished using these criteria in fiscal year 2015. We hypothesized more frequent admissions, greater mortality, longer LOS, and less likely shorter TDA in the malnourished patients...
January 31, 2018: JPEN. Journal of Parenteral and Enteral Nutrition
Aspen T Reese, Kyrstin Lulow, Lawrence A David, Justin P Wright
Soils harbor large, diverse microbial communities critical for local and global ecosystem functioning that are controlled by multiple and poorly understood processes. In particular, while there is observational evidence of relationships between both biotic and abiotic conditions and microbial composition and diversity, there have been few experimental tests to determine the relative importance of these two sets of factors at local scales. Here, we report the results of a fully factorial experiment manipulating soil conditions and plant cover on old-field mesocosms across a latitudinal gradient...
January 2018: Ecology and Evolution
Weiliang Hou, Jie Bao
Simultaneous saccharification and fermentation (SSF) is the most efficient operation in biorefining conversion, but aerobic SSF under high solids loading significantly faces the serious oxygen transfer limitation. This study took the first insight into an aerobic SSF by high oxygen demanding filamentous fungi in highly viscous lignocellulose hydrolysate. The results show that oxygen requirement in the aerobic SSF by Aspergillus niger was well satisfied for production of cellulosic citric acid. The record high citric acid titer of 136...
January 4, 2018: Bioresource Technology
Aspen Workman, Liqian Zhu, Brittney N Keel, Timothy P L Smith, Clinton Jones
Sensory neurons in trigeminal ganglia (TG) of calves latently infected with bovine herpesvirus 1 (BoHV-1) abundantly express latency-related (LR) gene products, including a protein (ORF2) and two micro-RNAs. Recent studies in mouse neuroblastoma cells (Neuro-2A) demonstrated ORF2 interacts with β-catenin and a β-catenin coactivator, high mobility group AT-hook 1 protein (HMGA1), which correlates with increased β-catenin dependent transcription and cell survival. β-catenin and HMGA1 are readily detected in a subset of latently infected TG neurons, but not TG neurons from uninfected calves or reactivation from latency...
January 10, 2018: Journal of Virology
G D Ceniccola, T P Holanda, R S F Pequeno, V S Mendonça, A B M Oliveira, L S F Carvalho, I de Brito-Ashurst, W M C Araújo
PURPOSE: Malnutrition is prevalent in the intensive care units (ICU), yet, there is a paucity of validated assessment tools. Subsequently, this study evaluates the validity of the malnutrition AND-ASPEN tool as an ICU mortality predictor. METHODS: Patients admitted to a large mixed ICU (72 beds) from 2014 to 2016, were followed during stay and had electronic health records on sex, age, Apache II and baseline nutrition assessment collected at admission. Patients with shortstay (<48h) and missing data were excluded...
December 21, 2017: Journal of Critical Care
Elizabeth K Duperret, Megan C Wise, Aspen Trautz, Daniel O Villarreal, Bernadette Ferraro, Jewell Walters, Jian Yan, Amir Khan, Emma Masteller, Laurent Humeau, David B Weiner
Immune checkpoint blockade antibodies are setting a new standard of care for cancer patients. It is therefore important to assess any new immune-based therapies in the context of immune checkpoint blockade. Here, we evaluate the impact of combining a synthetic consensus TERT DNA vaccine that has improved capacity to break tolerance with immune checkpoint inhibitors. We observed that blockade of CTLA-4 or, to a lesser extent, PD-1 synergized with TERT vaccine, generating more robust anti-tumor activity compared to checkpoint alone or vaccine alone...
November 21, 2017: Molecular Therapy: the Journal of the American Society of Gene Therapy
Nicholas John Deacon, Jake Joseph Grossman, Anna Katharina Schweiger, Isabella Armour, Jeannine Cavender-Bares
PREMISE OF THE STUDY: Aspen groves along the Niobrara River in Nebraska have long been a biogeographic curiosity due to morphological differences from nearby remnant Populus tremuloides populations. Pleistocene hybridization between P. tremuloides and P. grandidentata has been proposed, but the nearest P. grandidentata populations are currently several hundred kilometers east. We tested the hybrid-origin hypothesis using genetic data and characterized putative hybrids phenotypically. METHODS: We compared nuclear microsatellite loci and chloroplast sequences of Niobrara River aspens to their putative parental species...
December 15, 2017: American Journal of Botany
Benjamin Bollhöner, Soile Jokipii-Lukkari, Joakim Bygdell, Simon Stael, Mathilda Adriasola, Luis Muñiz, Frank Van Breusegem, Inés Ezcurra, Gunnar Wingsle, Hannele Tuominen
Metacaspases (MCs) are cysteine proteases that are implicated in programmed cell death of plants. AtMC9 (Arabidopsis thaliana Metacaspase9) is a member of the Arabidopsis MC family that controls the rapid autolysis of the xylem vessel elements, but its downstream targets in xylem remain uncharacterized. PttMC13 and PttMC14 were identified as AtMC9 homologs in hybrid aspen (Populus tremula × tremuloides). A proteomic analysis was conducted in xylem tissues of transgenic hybrid aspen trees which carried either an overexpression or an RNA interference construct for PttMC13 and PttMC14...
December 15, 2017: New Phytologist
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"