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https://www.readbyqxmd.com/read/28445365/improvement-of-flap-necrosis-in-a-rat-random-skin-flap-model-by-in-vivo-electroporation-mediated-hgf-gene-transfer
#1
S Morteza Seyed Jafari, Maziar Shafighi, Helmut Beltraminelli, Thomas Geiser, Robert E Hunger, Amiq Gazdhar
BACKGROUND: Despite great understanding of underlying mechanisms for flap necrosis and advances in surgical techniques, flap necrosis remains a critical issue. In the present study, the authors investigated the efficacy of electroporation-mediated hepatocyte growth factor (HGF) gene delivery to random dorsal skin flaps (McFarlane) to accelerate wound healing and reduce flap necrosis. METHODS: Fifteen male Wistar rats (290 to 320 g) were divided randomly into three groups...
May 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28444768/implantable-doppler-monitoring-of-buried-free-flaps-during-vascularized-lymph-node-transfer
#2
Chad M Teven, Adrian S H Ooi, Amir Inbal, David W Chang
BACKGROUND AND OBJECTIVES: Reliable flap monitoring is crucial to the success of free tissue transfer, including vascularized lymph node transfer (VLNT). However, no large-scale study has examined implantable Doppler monitoring in VLNT. We aimed to determine whether an implantable Doppler system can reliably monitor flap perfusion during VLNT and also to calculate the sensitivity and specificity of this system for detecting compromise in the monitored vessel. METHODS: An analysis of prospectively collected data of patients who underwent buried VLNT with implantable Doppler monitoring between 2014 and 2015 was performed...
April 25, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28444128/low-dose-ionizing-radiation-induces-therapeutic-neovascularization-in-a-pre-clinical-model-of-hindlimb-ischemia
#3
Augusto Ministro, Paula de Oliveira, Raquel J Nunes, André Dos Santos Rocha, Adriana Correia, Tânia Carvalho, José Rino, Pedro Faísca, Jorg D Becker, J Goyri-O'Neill, Filomena Pina, Esmeralda Poli, Bruno Silva-Santos, Fausto Pinto, Marc Mareel, Karine Serre, Susana Constantino Rosa Santos
We have previously shown that low-dose ionizing radiation (LDIR) induces angiogenesis but there is no evidence that they induce neovascularization in the setting of peripheral arterial disease. Here, we investigated the use of LDIR as an innovative and non-invasive strategy to stimulate therapeutic neovascularization using a model of experimentally induced hindlimb ischemia (HLI). Methods and results: After surgical induction of unilateral HLI, both hindlimbs of female C57BL/6 mice were sham-irradiated or irradiated with four daily fractions of 0...
April 19, 2017: Cardiovascular Research
https://www.readbyqxmd.com/read/28439427/double-aorta-artifact-in-sonography-a-diagnostic-challenge
#4
REVIEW
Robert Hadzik, Przemysław Bombiński, Michał Brzewski
The double aorta artifact was described and studied thoroughly twenty-five years ago. Despite this, it is still not commonly known today and can cause diagnostic difficulty. Total aortic duplication can be considered an anatomic defect whilst partial duplication mimics aortic dissection. In the literature, this artifact has been compared with a very rare anomaly, i.e. the occurrence of two aortas in one patient. Currently, however, the differentiation of this artifact from abdominal aortic dissection seems to be of greater significance...
March 2017: Journal of Ultrasonography
https://www.readbyqxmd.com/read/28436412/subinguinal-microsurgical-varicocelectomy-with-intraoperative-microvascular-doppler-ultrasound-leads-to-the-pain-free-outcome-after-surgery
#5
Kun-Long Lv, Ya-Dong Zhang, Jin-Tao Zhuang, Yong Gao, Liang Zhao, Zi Wan, Ming-Kuan Zhou, Jing-Wei Yu, Xiang-Zhou Sun, Yuan-Yuan Zhang, Xiang-An Tu
OBJECTIVE: To determine efficacy of intraoperative microvascular Doppler ultrasound in assisting subinguinal microsurgical varicocelectomy for pain relief in the treatment of painful varicoceles, compared to the microsurgery without Doppler ultrasound. METHODS: Total 153 patients underwent microsurgical varicocelectomy were randomly allocated to two groups: Groups 1 and 2 included 82 and 71 patients monitored with and without using intraoperative microvascular Doppler ultrasound, respectively...
April 18, 2017: Journal of X-ray Science and Technology
https://www.readbyqxmd.com/read/28435568/early-vessels-exploration-of-pink-pulseless-hand-in-gartland-iii-supracondylar-fracture-humerus-in-children-facts-and-controversies
#6
T Z Tunku-Naziha, Wms Wan-Yuhana, D Hadizie, Muhammad-Paiman, S Abdul-Nawfar, W S Wan-Azman, M S Arman-Z, S Abdul-Razak, M Z Rhendra-Hardy, W I Wan-Faisham
The management of pink pulseless limbs in supracondylar fractures has remained controversial, especially with regards to the indication for exploration in a clinically well-perfused hand. We reviewed a series of seven patients who underwent surgical exploration of the brachial artery following supracondylar fracture. All patients had a non-palpable radial artery, which was confirmed by Doppler ultrasound. CT angiography revealed complete blockage of the artery with good collateral and distal run-off. Two patients were more complicated with peripheral nerve injuries, one median nerve and one ulnar nerve...
March 2017: Malaysian Orthopaedic Journal
https://www.readbyqxmd.com/read/28422657/phased-array-ultrasound-system-for-planar-flow-mapping-in-liquid-metals
#7
Kevin Mader, Richard Nauber, Vladimir Galindo, Hannes Beyer, Lars Buttner, Sven Eckert, Jurgen Czarske
Controllable magnetic fields can be used to optimize flows in technical and industrial processes involving liquid metals in order to improve quality and yield. However, experimental studies in magnetohydrodynamics (MHD) often involve complex, turbulent flows and require planar, two-component velocity measurements through only one acoustical access. We present the phased array ultrasound Doppler velocimeter (PAUDV) as a modular research platform for flow mapping in liquid metals. It combines the pulse wave Doppler method with the phased array technique to adaptively focus the ultrasound beam...
April 12, 2017: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/28420337/right-aortic-arch-analysis-anatomical-variant-or-serious-vascular-defect
#8
Agata Arazińska, Michał Polguj, Konrad Szymczyk, Magdalena Kaczmarska, Łukasz Trębiński, Ludomir Stefańczyk
BACKGROUND: The right-sided aortic arch (RAA) is a rare congenital defect of the aorta. The aim of the study was to assess the occurrence of RAA in diagnoses performed by the University Radiology Department and analyze the frequency of concomitant vascular abnormalities. METHODS: The database of the Radiology Department was retrospectively analyzed between January 2008 and May 2016 with the keyword "right aortic arch". Twenty patients with this diagnosis were identified from a total of 11,690 CT examinations of the chest area, 19,623 CT examinations of brain-supplying vessels, and 1863 MRI examinations of the heart and aortic arch or brain-supplying arteries...
April 19, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28417646/cerebral-hemodynamic-assessment-and-neuroimaging-across-the-lifespan-in-sickle-cell-disease
#9
Lori C Jordan, Michael R DeBaun
Children and adults with sickle cell anemia (SCA) have a higher risk of strokes compared to age- and race-matched peers. Velocity in the middle cerebral or distal internal carotid artery as measured by transcranial Doppler ultrasound is a recognized method to identify children but not adults with SCA at high-risk for first stroke. For both children and adults with SCA that have had a stroke, no methods clearly identify individuals at highest risk of recurrent strokes or an initial silent stroke, the most common neurological injury...
January 1, 2017: Journal of Cerebral Blood Flow and Metabolism
https://www.readbyqxmd.com/read/28416004/clinical-study-of-children-with-takayasu-arteritis-a-retrospective-study-from-a-single-center-in-china
#10
Ye Feng, Xuemei Tang, Mingyue Liu, Juan Zhou, Xiaodong Zhao, Qiu Li
BACKGROUND: Delayed diagnosis of childhood Takayasu arteritis (TA) is common due to its atypical symptoms. The objective of the present study was to summarize the clinical features of childhood TA to raise awareness and improve management. METHODS: Eleven children diagnosed with TA at our hospital were enrolled. Clinical information, diagnosis, treatment, and outcome were then examined retrospectively. The Pediatric Vasculitis Activity Score (PVAS) and the Indian Takayasu Clinical Activity Score (ITAS2010) were used to assess disease activity...
April 17, 2017: Pediatric Rheumatology Online Journal
https://www.readbyqxmd.com/read/28401194/effect-of-electrical-stimulation-on-blood-flow-velocity-and-vessel-size
#11
Hee-Kyung Jin, Tae-Yeon Hwang, Sung-Hyoun Cho
Interferential current electrical stimulation alters blood flow velocity and vessel size. We aimed to investigate the changes in the autonomic nervous system depending on electrical stimulation parameters. Forty-five healthy adult male and female subjects were studied. Bipolar adhesive pad electrodes were used to stimulate the autonomic nervous system at the thoracic vertebrae 1-4 levels for 20 min. Using Doppler ultrasonography, blood flow was measured to determine velocity and vessel size before, immediately after, and 30 min after electrical stimulation...
January 2017: Open Medicine (Warsaw, Poland)
https://www.readbyqxmd.com/read/28399196/combined-use-of-laser-doppler-flowmetry-and-skin-thermometry-for-functional-diagnostics-of-intradermal-finger-vessels
#12
Evgeny A Zherebtsov, Angelina I Zherebtsova, Alexander Doronin, Andrey V Dunaev, Konstantin V Podmasteryev, Alexander Bykov, Igor Meglinski
No abstract text is available yet for this article.
April 1, 2017: Journal of Biomedical Optics
https://www.readbyqxmd.com/read/28398691/infrared-thermal-imaging-and-doppler-vessel-pressurization-ultrasonography-to-detect-lower-extremity-deep-vein-thrombosis-diagnostic-accuracy-study
#13
Fangge Deng, Qing Tang, Mei Jiang, Nanshan Zhong, Guanghua Liu
BACKGROUND AND OBJECTIVE: Infrared thermal imaging (IRTI) is a new technique for detecting deep vein thrombosis (DVT) based on DVT's infrared presentation and distribution characteristics (PDCs). A method that is singularly sensitive to DVT is needed. We therefore enrolled 157 subjects with suspected lower extremity DVT in a double-blind, controlled clinical trial using IRTI and Doppler compression ultrasonography (CPUS) to verify the clinical value of IRTI. METHODS: An IRTI system could precisely measure and store real-time thermal images...
April 11, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/28392853/pulsatility-index-of-popliteal-artery-in-patients-with-isolated-calf-vein-thrombosis-a-novel-technique-for-detecting-thrombosis
#14
Abdussamet Batur, Vural Polat, Mesut Ozgokce, Muhammed Alpaslan, Alpaslan Yavuz, Harun Arslan, Aydin Bora, Mehmet Emin Sakarya
BACKGROUND: To investigate the usefulness of popliteal artery spectral doppler findings as a complimentary approach to isolated calf vein thrombosis (DVT). MATERIAL/METHODS: We included consecutive patients presenting with symptomatic and sonographically proven acute isolated calf DVT. Patients with thrombosis of any other vein were excluded. We classified calf vein into into four main types. We investigated how many of these four vessels had DVT and compared them with respect to the pulsatility index (PI) value of the popliteal artery...
2017: Polish Journal of Radiology
https://www.readbyqxmd.com/read/28375834/the-role-of-ultrasound-in-the-diagnosis-and-follow-up-of-large-vessel-vasculitis-an-update
#15
Giuseppe Germanò, Sara Monti, Cristina Ponte, Niccolo' Possemato, Roberto Caporali, Carlo Salvarani, Pierluigi Macchioni, Nicolò Pipitone
Large-vessel vasculitides comprise giant cell arteritis and Takayasu's arteritis. In both conditions, early changes consist of transmural inflammation of the arterial wall, while later complications include lumen changes, such as stenoses or aneurysms. Colour-Doppler sonography has the ability to depict the arterial wall as well as the lumen, and is therefore ideally suited both to diagnose early vasculitis and to monitor patients over time. In this review article, we addressed the following issues: 1) the role of colour-Doppler sonography in the diagnosis of large-vessel vasculitis and its common pitfalls; 2) whether colour-Doppler sonography can increase the yield of temporal artery biopsy in giant cell arteritis; 3) the role of colour-Doppler sonography in monitoring patients with LVV over time; and 4) how colour-Doppler sonography performs compared to other imaging techniques...
March 29, 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/28367643/computational-fluid-dynamics-in-abdominal-aorta-bifurcation-non-newtonian-versus-newtonian-blood-flow-in-a-real-case-study
#16
Armando A Soares, Sílvia Gonzaga, Carlos Oliveira, André Simões, Abel I Rouboa
Hemodynamic in abdominal aorta bifurcation was investigated in a real case using computational fluid dynamics. A Newtonian and non-Newtonian (Walburn-Schneck) viscosity models were compared. The geometrical model was obtained by 3D reconstruction from CT-scan and hemodynamic parameters obtained by laser-Doppler. Blood was assumed incompressible fluid, laminar flow in transient regime and rigid vessel wall. Finite volume-based was used to study the velocity, pressure, wall shear stress (WSS) and viscosity throughout cardiac cycle...
April 3, 2017: Computer Methods in Biomechanics and Biomedical Engineering
https://www.readbyqxmd.com/read/28367084/interrelationship-between-insulin-resistance-and-portal-haemodynamic-abnormality-in-cirrhosis
#17
Hitoshi Maruyama, Kazufumi Kobayashi, Soichiro Kiyono, Osamu Yokosuka
Background: There are only limited data regarding the effect of impaired portal circulation on the glucose metabolism. The study prospectively examined the interrelationship between insulin resistance (IR) and portal haemodynamic abnormality in cirrhosis. Methods: There were 53 cirrhosis patients (61.6 ± 13.0 years) all presenting gastroesophageal varices. Portal haemodynamics by both hepatic venous catheterisation and Doppler ultrasound were examined with respect to the homeostasis model assessment (HOMA)-IR and HOMA2-IR...
2017: International Journal of Medical Sciences
https://www.readbyqxmd.com/read/28366306/the-largpad-trial-phase-iia-evaluation-of-l-arginine-infusion-in-patients-with-peripheral-arterial-disease
#18
Vikram S Kashyap, Ryan O Lakin, Patricia Campos, Matthew Allemang, Ann Kim, Timur P Sarac, Alfred Hausladen, Jonathan S Stamler
OBJECTIVE: Endothelial function is improved by l-arginine (l-arg) supplementation in preclinical and clinical studies of mildly diseased vasculature; however, endothelial function and responsiveness to l-arg in severely diseased arteries is not known. Our objective was to evaluate the acute effects of catheter-directed l-arg delivery in patients with chronic lower extremity ischemia secondary to peripheral arterial disease. METHODS: The study enrolled 22 patients (45% male) with peripheral arterial disease (mean age, 62 years) requiring lower extremity angiography...
March 30, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28366179/effect-of-self-expanding-carotid-stents-on-plaque-thickness-and-vessel-diameter
#19
Rafael Martínez-Pérez, Graeme Marchuk, Donald H Lee, David M Pelz, Stephen P Lownie
BACKGROUND: In vitro models have suggested that stents affect atherosclerotic plaques symmetrically because of their outward radial forces. We evaluated the effects of stents on carotid plaque and the arterial wall using carotid ultrasound in carotid stenting patients to see whether these effects were borne out in vivo. METHODS: From a carotid stent database, 30 consecutive patients were selected. All had carotid Doppler ultrasound performed pre- and poststenting...
April 3, 2017: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://www.readbyqxmd.com/read/28366054/advanced-imaging-in-acute-ischemic-stroke
#20
REVIEW
Craig Kilburg, J Scott McNally, Adam de Havenon, Philipp Taussky, M Yashar S Kalani, Min S Park
The evaluation and management of acute ischemic stroke has primarily relied on the use of conventional CT and MRI techniques as well as lumen imaging sequences such as CT angiography (CTA) and MR angiography (MRA). Several newer or less-established imaging modalities, including vessel wall MRI, transcranial Doppler ultrasonography, and 4D CTA and MRA, are being developed to complement conventional CT and MRI techniques. Vessel wall MRI provides high-resolution analysis of both extracranial and intracranial vasculature to help identify previously occult lesions or characteristics of lesions that may portend a worse natural history...
April 2017: Neurosurgical Focus
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