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https://www.readbyqxmd.com/read/29776846/moderators-of-angiogenesis-in-muscle-flaps-a-non-randomised-animal-study
#1
Kimberley Bradshaw, Michael Wagels
INTRODUCTION: A muscle flap can survive a pedicle injury under favourable conditions. In the reconstruction of compound limb injuries, the wound milieu is variable and may affect the rate and manner of neovascularisation. Our aim is to determine the effect of some key clinical variables on neovascularisation in muscle flaps in an animal model. METHODOLOGY: The pectoralis profundus was raised in 60 rats and covered with a skin graft. Fifteen rats were allocated to each of the following groups: separation of the flap from the skin inset (S), inflammation by inoculation with Staphylococcus aureus (I), flap elevation with harmonic scalpel (H) and preservation of the motor nerve (N) as well as compared to controls (C)...
April 23, 2018: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/29775982/the-supraclavicular-artery-perforator-flap-a-comparative-study-of-imaging-techniques-used-in-preoperative-mapping
#2
Hemin Oathman Sheriff, Kawa Abdullah Mahmood, Nzar Hamawandi, Aram Jamal Mirza, Jawad Hawas, Esther Granell Moreno, Juan Antonio Clavero, Christopher Hankins, Jaume Masia
BACKGROUND:  The supraclavicular artery flap is an excellent flap for head and neck reconstruction. The aim of this study is to assess imaging techniques to define the precise vascular boundaries of this flap. METHODS:  Six imaging techniques were used for supraclavicular artery mapping in 65 cases; handheld Doppler, triplex ultrasound, computed tomography angiography, magnetic resonance angiography, digital subtraction angiography, and indocyanine green angiography...
May 18, 2018: Journal of Reconstructive Microsurgery
https://www.readbyqxmd.com/read/29774429/the-utility-of-superb-microvascular-imaging-for-the-detection-of-deep-vein-thrombosis
#3
Yuta Hagiwara, Rie Sasaki, Takahiro Shimizu, Kaima Soga, Chihiro Hatada, Motoki Miyauchi, Takanori Okamura, Masaru Sakurai, Hisanao Akiyama, Yasuhiro Hasegawa
Superb microvascular imaging (SMI) reduces motion artifacts significantly and allows visualization of low-velocity blood flow in vessels; thus, thrombi are clearly demonstrated compared to conventional B-mode and color Doppler imaging. Ultrasonographic images of the lower extremities of a 69-year-old woman with acute ischemic stroke complicated with deep vein thrombosis (DVT) are presented. Because SMI allows visualization of low-velocity blood flow, echo contrast between the thrombus and the surrounding flow makes it possible to clearly visualize the thrombus...
May 17, 2018: Journal of Medical Ultrasonics
https://www.readbyqxmd.com/read/29768474/sonographic-visualization-of-nipple-blood-flow-can-help-differentiate-paget-disease-from-benign-eczematous-nipple-lesions
#4
Hideaki Ogata, Yukio Mitsuzuka, Naoko Honma, Miho Yoshida, Makoto Sumazaki, Fumi Saito, Masahiro Kobayashi, Kazutoshi Shibuya, Tetsuo Mikami, Hironori Kaneko
PURPOSE: Paget disease of the breast is a rare cancer that originates from the nipple-areolar complex. It is often overlooked and misdiagnosed as benign chronic eczema of the nipple. We aimed to retrospectively verify whether blood flow analysis using Doppler sonography was useful for detecting the presence of Paget disease. METHODS: In this retrospective study, 12 patients with pathologically proven unilateral nipple eczematous lesions (seven with Paget disease and five with simple dermatitis) were included...
2018: PloS One
https://www.readbyqxmd.com/read/29766604/sodium-nitroglycerin-induces-middle-cerebral-artery-vasodilation-in-young-healthy-adults
#5
Jenna M Schulz, Baraa K Al-Khazraji, J Kevin Shoemaker
Recent evidence indicates that basal cerebral conduit vessels dilate with hypercapnia, with a nitric oxide (NO) mechanism explaining one way in which parenchymal cerebral arterioles dilate. However, whether NO affects basal cerebral artery dilation remains unknown. This study quantified the effect of an exogenous NO donor [sodium nitroglycerin (NTG); 0.4 mg sublingual spray] on the right middle cerebral artery (rMCA) cross-sectional area (CSA), blood velocity and overall blood flow. Measures of vessel CSA (7 Tesla magnetic resonance imaging) and MCA blood velocity (transcranial Doppler ultrasound) were made at baseline (BL), and following exogenous NTG or placebo (PLO) administration in young, healthy individuals (n = 10, 2 males, age range 20-23 years)...
May 15, 2018: Experimental Physiology
https://www.readbyqxmd.com/read/29763966/quantitative-analysis-of-thyroid-tumors-vascularity-a-comparison-between-3-d-contrast-enhanced-ultrasound-and-3-d-power-doppler-on-benign-and-malignant-thyroid-nodules
#6
Cristina Caresio, Marco Caballo, Maurilio Deandrea, Roberto Garberoglio, Alberto Mormile, Ruth Rossetto, Paolo Limone, Filippo Molinari
PURPOSE: To perform a comparative quantitative analysis of Power Doppler ultrasound (PDUS) and Contrast-Enhancement ultrasound (CEUS) for the quantification of thyroid nodules vascularity patterns, with the goal of identifying biomarkers correlated to the malignancy of the nodule with both imaging techniques. METHODS: We propose a novel method to reconstruct the vascular architecture from 3-D PDUS and CEUS images of thyroid nodules, and to automatically extract seven quantitative features related to the morphology and distribution of vascular network...
May 15, 2018: Medical Physics
https://www.readbyqxmd.com/read/29760987/5-ala-fluorescence-and-laser-doppler-flowmetry-for-guidance-in-a-stereotactic-brain-tumor-biopsy
#7
Neda Haj-Hosseini, Johan C O Richter, Peter Milos, Martin Hallbeck, Karin Wårdell
A fiber optic probe was developed for guidance during stereotactic brain biopsy procedures to target tumor tissue and reduce the risk of hemorrhage. The probe was connected to a setup for the measurement of 5-aminolevulinic acid (5-ALA) induced fluorescence and microvascular blood flow. Along three stereotactic trajectories, fluorescence (n = 109) and laser Doppler flowmetry (LDF) (n = 144) measurements were done in millimeter increments. The recorded signals were compared to histopathology and radiology images...
May 1, 2018: Biomedical Optics Express
https://www.readbyqxmd.com/read/29757059/quantitative-hemodynamic-analysis-of-cerebral-blood-flow-and-neurovascular-coupling-using-optical-coherence-tomography-angiography
#8
Paul Shin, WooJhon Choi, JongYoon Joo, Wang-Yuhl Oh
Functional hyperemia in the rat cortex was investigated using high-speed optical coherence tomography (OCT) angiography and Doppler OCT. OCT angiography (OCTA) was performed to image the hemodynamic stimulus-response over a wide field of view. Temporal changes in vessel diameters in different vessel compartments, which were determined as the diameters of erythrocyte flows in OCT angiograms, were measured in order to monitor localized hemodynamic changes. Our results showed that the dilation of arterioles at the site of activation was accompanied by the dilation of upstream arteries...
January 1, 2018: Journal of Cerebral Blood Flow and Metabolism
https://www.readbyqxmd.com/read/29755714/identification-of-cerebral-artery-stenosis-using-bilateral-photoplethysmography
#9
Hyun Goo Kang, Seogki Lee, Han Uk Ryu, Youngsuk Shin
Cerebral artery stenosis is currently diagnosed by transcranial Doppler (TCD), computed tomographic angiography (CTA), or magnetic resonance angiography (MRA). CTA exposes a patient to radiation, while CTA and MRA are invasive and side effects were related to contrast medium use. This study aims to provide a technique that can simply discriminate between people with normal blood vessels and those with cerebral artery stenosis using photoplethysmography (PPG), which is noninvasive and inexpensive. Moreover, the measurement takes only 120 seconds and is conducted on the fingers...
2018: Journal of Healthcare Engineering
https://www.readbyqxmd.com/read/29753425/-the-contribution-of-systematic-implementation-of-cardiovascular-explorations-for-the-detection-of-cardiac-sources-of-embolism-in-patients-with-stroke-about-230-patients
#10
A Hadi, L Bendriss, A Khatouri
OBJECTIVES: Ischemic stroke are estimated at 80% of all strokes. Embolism of cardiac origin accounts for around 20% of them. The aim of our study is to report the contribution of cardiovascular investigations performed as a routine during the evaluation of patients with ischemic stroke. PATIENTS AND METHODS: This is a retrospective study of ischemic stroke cases collated in Cardiology department of the military hospital of Marrakech between January 2010 and December 2014...
May 9, 2018: Annales de Cardiologie et D'angéiologie
https://www.readbyqxmd.com/read/29743525/design-characterization-and-in-vivo-performance-of-synthetic-2-mm-diameter-vessel-grafts-made-of-pva-gelatin-blends
#11
M Atlan, T Simon-Yarza, J M Ino, V Hunsinger, L Corté, P Ou, R Aid-Launais, M Chaouat, D Letourneur
Since the development of the first vascular grafts, fabrication of vessel replacements with diameters smaller than 6 mm remains a challenge. The present work aimed to develop PVA (poly (vinyl alcohol))-gelatin hybrids as tubes suitable for replacement of very small vessels and to evaluate their performance using a rat abdominal aorta interposition model. PVA-gelatin hybrid tubes with internal and external diameters of 1.4 mm and 1.8 mm, respectively, composed of 4 different gelatin ratios were prepared using a one-step strategy with both chemical and physical crosslinking...
May 9, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29742984/maternal-serum-endocan-concentration-in-pregnancies-complicated-by-intrauterine-growth-restriction
#12
Agata Szpera-Gozdziewicz, Katarzyna Kosicka, Tomasz Gozdziewicz, Mariola Krzyscin, Przemyslaw Wirstlein, Anna Siemiatkowska, Franciszek Glowka, Ewa Wender-Ozegowska, Grzegorz H Breborowicz
OBJECTIVES: Endocan plays a role in the development of vascular tissue in health and disease and is an indicator of endothelial cells activation and angiogenesis. Therefore, this study aimed to investigate the relationship between maternal endocan serum level and intrauterine growth restriction (IUGR) as well as ultrasound Doppler flow measurements indicating placental insufficiency. METHODS: This study included a group of women with IUGR (n = 37) and a group of healthy pregnant women (controls, n = 37)...
January 1, 2018: Reproductive Sciences
https://www.readbyqxmd.com/read/29735316/use-of-contrast-enhanced-ultrasound-in-the-assessment-of-uterine-fibroids-a-feasibility-study
#13
Barbara Stoelinga, Anniek M C Dooper, Lynda J M Juffermans, Arnoud W Postema, Hessel Wijkstra, Hans A M Brölmann, Judith A F Huirne
Contrast-enhanced ultrasound (CEUS) is an innovative ultrasound technique capable of visualizing both the macro- and microvasculature of tissues. In this prospective pilot study, we evaluated the feasibility of using CEUS to visualize the microvasculature of uterine fibroids and compared CEUS with conventional ultrasound. Four women with fibroids underwent gray-scale ultrasound, sonoelastography and power/color Doppler scans followed by CEUS examination. Analysis of CEUS images revealed initial perfusion of the peripheral rim, that is, a pseudo-capsule, followed by enhancement of the entire lesion through vessels traveling from the exterior to the interior of the fibroid...
May 4, 2018: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/29732592/transcranial-doppler-ultrasound-in-peninsular-arab-patients-with-sickle-cell-disease
#14
Adekunle Adekile, Meaad Hassan, Akram Asbeutah, Mohamed Al-Hinai, Omar Trad, Nayef Farhan
OBJECTIVES: Transcranial Doppler ultrasound is used to identify patients with sickle cell disease (SCD) at risk for stroke. We performed transcranial Doppler studies in patients from 4 countries in the Arabian Peninsula (Kuwait, Oman, Iraq, and United Arab Emirates) to document the prevalence of abnormal transcranial Doppler findings. METHODS: The patients were recruited from outpatient clinics and studied in a steady state. Transcranial Doppler examinations were performed with standard equipment by experienced operators...
May 6, 2018: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/29730685/the-microvascular-and-morphostructural-changes-of-nails-in-psoriatic-patients-with-nail-disease-a-link-between-ultrasound-and-videocapillaroscopy-findings-in-the-nailfold
#15
Sibel Bakirci Ureyen, Rabia Oztas Kara, Zeynep Erturk, Mahizer Yaldiz
OBJECTIVE: The objective of this study is to evaluate the link between nail fold vessel resistive index (NVRI) measured by ultrasound (US) and capillary loops diameters measured using nailfold videocapillarascopy (NVC), and to assess the morphological appearance of the nail bed in patients with psoriatic nail disease (PND) as compared with healthy controls (HCs). MATERIAL AND METHODS: This study was conducted in patients with PND and HCs. General demographic data were collected and clinical assessments were performed for all subjects...
May 2, 2018: Medical Ultrasonography
https://www.readbyqxmd.com/read/29727515/microv-technology-to-improve-transcranial-color-coded-doppler-examinations
#16
Giovanni Malferrari, Giuseppe Pulito, Attilia Maria Pizzini, Nicola Carraro, Giorgio Meneghetti, Enzo Sanzaro, Patrizio Prati, Antonio Siniscalchi, Daniela Monaco
The purpose of this review is to provide an update on technology related to Transcranial Color Coded Doppler Examinations. Microvascularization (MicroV) is an emerging Power Doppler technology which can allow visualization of low and weak blood flows even at high depths, thus providing a suitable technique for transcranial ultrasound analysis. With MicroV, reconstruction of the vessel shape can be improved, without any overestimation. Furthermore, by analyzing the Doppler signal, MicroV allows a global image of the Circle of Willis...
May 4, 2018: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/29713549/microscopic-subinguinal-varicocelectomy-in-100-consecutive-cases-spermatic-cord-vascular-anatomy-recurrence-and-hydrocele-outcome-analysis
#17
Ahmed M Al-Kandari, Abdulnasser Khudair, Abdelghaffar Arafa, Fouad Zanaty, Ahmed Ezz, Mohamed El-Shazly
Objective: To evaluate the detailed vascular anatomy of the spermatic cord during subinguinal microscopic varicocelectomy and to assess the outcome of the cases with regard to varicocele recurrence and hydrocele formation. Patients and methods: In all, 100 varicocele cases including 74 left-sided and 26 bilateral, comprising 126 spermatic cord units with clinically palpable varicoceles underwent microscopic subinguinal varicocelectomy. Detailed description of vascular anatomy of the spermatic cords was reported...
March 2018: Arab Journal of Urology
https://www.readbyqxmd.com/read/29708204/through-the-hololens%C3%A2-looking-glass-augmented-reality-for-extremity-reconstruction-surgery-using-3d-vascular-models-with-perforating-vessels
#18
Philip Pratt, Matthew Ives, Graham Lawton, Jonathan Simmons, Nasko Radev, Liana Spyropoulou, Dimitri Amiras
Precision and planning are key to reconstructive surgery. Augmented reality (AR) can bring the information within preoperative computed tomography angiography (CTA) imaging to life, allowing the surgeon to 'see through' the patient's skin and appreciate the underlying anatomy without making a single incision. This work has demonstrated that AR can assist the accurate identification, dissection and execution of vascular pedunculated flaps during reconstructive surgery. Separate volumes of osseous, vascular, skin, soft tissue structures and relevant vascular perforators were delineated from preoperative CTA scans to generate three-dimensional images using two complementary segmentation software packages...
2018: European radiology experimental
https://www.readbyqxmd.com/read/29707395/fetal-sirenomelia-associated-with-an-abdominal-cyst-originating-from-a-saccular-cloaca
#19
Yui Kinjo, Hitoshi Masamoto, Hayase Nitta, Tadatsugu Kinjo, Tomoko Tamaki, Naoki Yoshimi, Yoichi Aoki
A 40-year-old pregnant woman presented with a fetal abdominal cyst and oligohydramnios. Color Doppler scan revealed a single blood vessel from the fetal aorta into a single umbilical artery. Severe oligohydramnios limited ultrasonographic evaluation of the fetal lower limbs, kidneys, or bladder. The pregnancy was terminated; the fetus showed fused lower limbs, bulging abdomen, and absent external genitalia and was diagnosed with type III sirenomelia. On autopsy, no normal bladder was observed, but duodenal atresia, anorectal atresia, and right renal agenesis were found...
2018: Case Reports in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29706899/development-of-the-human-placenta-and-fetal-heart-synergic-or-independent
#20
REVIEW
Graham J Burton, Eric Jauniaux
The placenta is the largest fetal organ, and toward the end of pregnancy the umbilical circulation receives at least 40% of the biventricular cardiac output. It is not surprising, therefore, that there are likely to be close haemodynamic links between the development of the placenta and the fetal heart. Development of the placenta is precocious, and in advance of that of the fetus. The placenta undergoes considerable remodeling at the end of the first trimester of pregnancy, and its vasculature is capable of adapting to environmental conditions and to variations in the blood supply received from the mother...
2018: Frontiers in Physiology
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