Qichen Zhou, Chao Zhang, Jiaxin Du, Ziyue Xin, Yapeng Qi, Yihan Wang, Shen-Jie Li, Weikan Wang, Chenglin Zhou, Jian-Ren Liu, Xiaoxia Du
Neurovascular coupling (NVC) provides new insights into migraine, a neurological disorder impacting over one billion people worldwide. This study compared NVC and cerebral blood flow (CBF) in patients with migraine without aura (MwoA) and healthy controls. About 55 MwoA patients in the interictal phase and 40 age- and sex-matched healthy controls underwent resting-state functional magnetic resonance imaging and arterial spin-labeling perfusion imaging scans. The CBF and resting-state neuronal activity indicators, including the amplitudes of low-frequency fluctuation (ALFF), regional homogeneity (ReHo), and degree centrality (DC), were calculated for each participant...
January 2024: Journal of Neuroscience Research