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Hidehiro Takei, Emilie Rouah, Yusuke Ishida
Metastases are the most common brain tumors especially in adults. Although they are generally considered a single disease entity which is universally fatal in patients with advanced cancer, brain metastases are remarkably heterogeneous both clinically and pathologically. As members of the multidisciplinary clinical team for the diagnosis and management of metastatic brain tumors, pathologists must be familiar not only with clinicopathologic features of brain metastases but also with any characteristic and clinically significant molecular findings...
January 2016: Brain Tumor Pathology
Hee Joung Kim, Seong Hui Kang, Hyun Woo Chung, Jong Sik Lee, Sun Jong Kim, Kwang Ha Yoo, Kye Young Lee
BACKGROUND: We have occasionally encountered advanced lung cancer patients with disseminated carcinomatosis throughout the body and/or within the lung. This study investigated the clinical characteristics and outcomes of advanced lung adenocarcinoma patients with miliary disseminated carcinomatosis. METHODS: Patients with adenocarcinomas harboring epidermal growth factor receptor (EGFR) mutations who presented with miliary disseminated carcinomatosis (either intrapulmonary or distant site) were enrolled in the study...
September 2015: Thoracic Cancer
Chor-Kuan Lim
No abstract text is available yet for this article.
September 2015: Journal of Thoracic Oncology
J Dumoulin, N Rozensztajn, M Paradis, J Sellier, A Abel, P Giraud, S Labrune, T Chinet
INTRODUCTION: Miliary brain metastases are a rare form of brain metastatic lesions. CASE REPORT: We report the case of a 58-year-old patient with lung adenocarcinoma and an EGFR mutation, who had metastatic lesions in the bones, pleura and pericardia at the time of diagnosis. The patient was treated with tyrosine kinase inhibitor. A few months later, he presented with progressive neuropsychiatric symptoms, which were attributed to miliary brain metastases based on the radiological pattern (micronodules, some of which were calcified) and the elimination of alternative possible diagnoses...
January 2016: Revue des Maladies Respiratoires
Sopa Pongpornsup, Pira Neungton, Somchai Chairoongruang, Piyaporn Apisamrnthanarak
OBJECTIVE: Determine the characteristic imaging findings and accuracy for diagnosis of peritoneal metastasis in gastric cancer by 64-slice multidetector computed tomography (MDCT). MATERIAL AND METHOD: A retrospective study was performed in 50 patients with gastric cancer who underwent 64-slice MDCT The patients were enrolled between January 2006 and March 2011. The MDCT scan ofabdomen from patients with gastric cancer was retrospectively evaluated by two gastrointestinal radiologists without knowledge of each patient s history, clinical data, and final diagnosis...
August 2014: Journal of the Medical Association of Thailand, Chotmaihet Thangphaet
Seerat Poonia, Eamon M Berge, Dara L Aisner, Denise Damek, Robert C Doebele
No abstract text is available yet for this article.
September 2014: Clinical Lung Cancer
Sanjeev Kumar Verma, Saurabh Karmakar
Tuberculosis is a disease with protean manifestations. We present a case which was initially suspected as bronchogenic carcinoma with lymphangitic carcinomatosis, based on radiological appearance but later diagnosed as pulmonary tuberculoma with military tuberculosis and silicosis after thoracotomy and open lung biopsy. The patient was treated successfully with Antituberculosis Therapy (ATT). Rarity of presentation in form of pulmonary tuberculoma co-existing with histological features of miliary tuberculosis and silicosis, led us to report this case...
February 2013: Journal of Clinical and Diagnostic Research: JCDR
Anastasia Oikonomou, Panos Prassopoulos
Septal, reticular, nodular, reticulonodular, ground-glass, crazy paving, cystic, ground-glass with reticular, cystic with ground-glass, decreased and mosaic attenuation pattern characterise interstitial lung diseases on high-resolution computed tomography (HRCT). Occasionally different entities mimic each other, either because they share identical HRCT findings or because of superimposition of patterns. Idiopathic pulmonary fibrosis (IPF), fibrosis associated with connective tissue disease, asbestosis, end-stage sarcoidosis or chronic hypersensitivity pneumonitis (HP) may present with lower zone, subpleural reticular pattern associated with honeycombing...
February 2013: Insights Into Imaging
Minehiko Inomata, Ryuji Hayashi, Kenta Kambara, Seisuke Okazawa, Shingo Imanishi, Tomomi Ichikawa, Kensuke Suzuki, Toru Yamada, Toshiro Miwa, Tatsuhiko Kashii, Shoko Matsui, Kazuyuki Tobe, Masakiyo Sasahara
INTRODUCTION: Miliary brain metastasis is an extremely rare form of brain metastasis which can present with atypical imaging findings. We report the case of a patient with miliary brain metastasis of lung cancer showing calcification in metastatic lesions. CASE PRESENTATION: A 68-year-old Japanese woman was diagnosed with lung adenocarcinoma. Brain computed tomography revealed multiple small calcified lesions in both cerebral hemispheres. Mutation of the epidermal growth factor receptor gene (exon 21, L858R) in lung cancer cells was detected, and treatment with gefitinib was initiated...
2012: Journal of Medical Case Reports
Shang-Gin Wu, Fu-Chang Hu, Yih-Leong Chang, Yung-Chie Lee, Chong-Jen Yu, Yeun-Chung Chang, Jenn-Yu Wu, Jin-Yuan Shih, Pan-Chyr Yang
Nonsmall cell lung cancer (NSCLC) presenting with miliary intrapulmonary carcinomatosis (MIPC) is rare. We investigated the clinical characteristics and epidermal growth factor receptor (EGFR) mutation rate of NSCLC patients with MIPC at initial diagnosis. From June 2004 to December 2008, we screened newly diagnosed NSCLC patients for MIPC using image-based criteria. We recorded clinical data and analysed EGFR mutation status. For comparison, we collected specimens from stage IV NSCLC patients without MIPC tested for EGFR mutations from April 2001 to November 2008...
February 2013: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
No abstract text is available yet for this article.
September 28, 1946: Medical Journal of Australia
A Targnion, B Broze, E Habonimana, H Jouan, B Frémond
We report on 2 cases of ovarian teratoma associated with gliomatosis peritonei in 2 young girls aged 9 and 14 years. Gliomatosis peritonei is an unusual miliary-like peritoneal carcinomatosis of glial tissue. In our experience, follow-up was important to detect abdominal recurrence of glial implants, which had to be removed by iterative surgery. We report a 14-year follow-up and an unusual pleural metastatic disease.
August 2010: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
Tomoyo Oguri, Satoru Ito, Mariko Morishita, Koji Sakamoto, Masashi Kondo, Yoshinori Hasegawa
A 55-year-old woman treated with infliximab for rheumatoid arthritis was admitted due to progressive ascites. A CT scan showed massive ascites, bilateral pleural effusion, disseminated granular shadows in the lung, and multiple swollen mediastinal lymph nodes. A FDG-PET/CT scan showed increases of FDG uptake in the mesentery and peritoneum, mimicking peritoneal carcinomatosis. Subsequent pleural and peritoneal fluid analysis showed elevated adenosine deaminase activity levels with no malignant cells. A right pleural biopsy specimen revealed Langhans giant cells and granulomas...
March 2010: Nihon Kokyūki Gakkai Zasshi, the Journal of the Japanese Respiratory Society
John Welch, Geoffrey Welsh
No abstract text is available yet for this article.
November 7, 2008: New Zealand Medical Journal
Spyros Milingos, Athanasios Protopapas, Christos Papadimitriou, Alexandros Rodolakis, George Kallipolitis, Nikolaos Skartados, Sophia Markaki, Meletios Athanasios Dimopoulos, Aris Antsaklis
STUDY OBJECTIVE: To assess whether laparoscopy is a reliable technique for the investigation of women presenting with ascites and in whom the diagnosis remains obscure. DESIGN: Prospective nonrandomized clinical study (Canadian Task Force classification II-2). SETTING: University Departments of a tertiary referral center. PATIENTS: Women presenting in our institution with ascites in whom the diagnosis remained obscure after an extensive nonoperative diagnostic work-up...
January 2007: Journal of Minimally Invasive Gynecology
Masahiro Sakai, Sadayuki Murayama, Masaki Gibo, Tamaki Akamine, Masatomi Yoshinaga, Shirou Iraha, Osamu Nagata
OBJECTIVE: The objective of this study was to evaluate whether maximum intensity projection (MIP) images increased the ability of experienced and resident radiologists to differentiate between the micronodular distribution of focal and diffuse infiltrative lung diseases. METHODS: The cases used in the study were those of 26 patients with focal or diffuse micronodular lung diseases, including 7 cases of sarcoidosis, 6 of miliary tuberculosis, 3 of pulmonary tuberculosis, 3 of chronic bronchitis, 2 of human T-lymphotropic virus type 1-associated bronchoalveolar disorder, 2 of diffuse aspiration bronchiolitis, 1 of atypical mycobacterial infection, and 1 of lymphangitic carcinomatosis...
September 2005: Journal of Computer Assisted Tomography
Abdulsalam S Ibrahim, Mona H Allangawi, Hisham A Sattar, Hassan S Mobyed, Ahmed A Almohammed
OBJECTIVES: To review the indications, diagnostic yields and complications of transbronchial biopsy (TBB) in a tertiary hospital in the State of Qatar. METHODS: A retrospective review of our records revealed 1006 adult flexible fibre optic bronchoscopies (FFB) at Hamad General Hospital, State of Qatar between January 1999 and December 2003. A total of 85 (8.4%) TBB were performed, but complete data were available for 71/85 (83.5%), which were reviewed for indications, diagnostic yields and complications...
April 2005: Saudi Medical Journal
R Ozaras, A D Celik, K Zengin, A Mert, R OzturkK, Y Cicek, E Tabak
Fever of unknown origin (FUO) is a diagnostic challenge for the practising physician. Detailed medical history, physical examination, non-invasive laboratory tests, and radiologic examinations compose the first level in the diagnostic approach to the FUO. When a diagnosis cannot be established with these procedures, some invasive diagnostic techniques and finally exploratory laparotomy are performed. Although advanced diagnostic measures and imaging-guided less invasive procedures have decreased the need, laparotomy remains as a final diagnostic method for FUO cases...
February 2005: Acta Chirurgica Belgica
No abstract text is available yet for this article.
February 1962: Laval Médical
No abstract text is available yet for this article.
June 1, 1955: Revue Médicale de Liège
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