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17-P for Preterm

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https://www.readbyqxmd.com/read/28081048/a-prospective-cohort-study-of-common-childhood-infections-in-south-african-hiv-exposed-uninfected-and-hiv-unexposed-infants
#1
Amy L Slogrove, Monika M Esser, Mark F Cotton, David P Speert, Tobias R Kollmann, Joel Singer, Julie A Bettinger
BACKGROUND: Much evidence of HIV-exposed uninfected (HEU) infant infectious morbidity predates availability of maternal combination antiretroviral therapy and does not control for universal risk factors (preterm birth, low birth weight, suboptimal breastfeeding and poverty). METHODS: This prospective cohort study identified HIV-infected and HIV-uninfected mothers and their newborns from South African community midwife unit. The primary outcome, infectious cause hospitalization or death before 6 months of age, was compared between HEU and HIV-unexposed (HU) infants and classified for type and severity using validated study-specific case definitions...
February 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/28079864/bronchopulmonary-dysplasia-and-pulmonary-hypertension-a-meta-analysis
#2
G Al-Ghanem, P Shah, S Thomas, L Banfield, S El Helou, C Fusch, A Mukerji
OBJECTIVE: Pulmonary hypertension (PH) is a complication of bronchopulmonary dysplasia (BPD) but the true impact of PH in patients with BPD remains unclear. We sought to systematically review and meta-analyze incidence of PH in BPD and compare clinical outcomes of BPD patients with PH to those without PH in preterm infants. STUDY DESIGN: Medline, Embase, PsychINFO and CINAHL were searched from January 2000 through December 2015. Cohort, case-control and randomized studies were included...
January 12, 2017: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/28079774/a-statewide-progestogen-promotion-program-in-ohio
#3
Jay D Iams, Mary S Applegate, Michael P Marcotte, Martha Rome, Michael A Krew, Jennifer L Bailit, Heather C Kaplan, Jessi Poteet, Melissa Nance, David S McKenna, Hetty C Walker, Jennifer Nobbe, Lakshmi Prasad, Maurizio Macaluso, Carole Lannon
OBJECTIVE: To promote use of progestogen therapy to reduce premature births in Ohio by 10%. METHODS: The Ohio Perinatal Quality Collaborative initiated a quality improvement project in 2014 working with clinics at 20 large maternity hospitals, Ohio Medicaid, Medicaid insurers, and service agencies to use quality improvement methods to identify eligible women and remove treatment barriers. The number of women eligible for prophylaxis, the percent prescribed a progestogen before 20 and 24 weeks of gestation, and barriers encountered were reported monthly...
January 9, 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28068860/does-adjunctive-use-of-progesterone-in-women-with-cerclage-improve-prevention-of-preterm-birth
#4
Rachel G Sinkey, Mercedes R Garcia, Anthony O Odibo
OBJECTIVE: To evaluate outcomes among pregnancies with cerclage as compared to cerclage and adjunctive progesterone. METHODS: A retrospective cohort study was performed from 10/1/11 - 6/30/15 including women with a singleton gestation with vaginal cerclage. Exclusion criteria included multiple gestations, simultaneous 17-alpha hydroxyprogesterone caproate (17-OHPC) and vaginal progesterone (vag-p) use, and patients lost to follow-up. Primary outcome was prevention of preterm birth less than 35 (PTB < 35) weeks gestational age (GA)...
January 9, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28065221/meta-analysis-of-aspirin-heparin-therapy-for-un-explained-recurrent-miscarriage
#5
Tong Ling, Wei Xian-Jiang
Objective This study was designed to evaluate the efficacy and safety of aspirin-heparin treatment for un-explained recurrent spontaneous abortion (URSA). Methods Literatures reporting the studies on the aspirin-heparin treatment of un-explained recurrent miscarriage with randomized controlled trials (RCTs) were collected from the major publication databases. The live birth rate was used as primary indicator, preterm delivery, preeclampsia, intrauterine growth restriction, and adverse reactions (thrombocytopenia ) were used as the secondary indicators...
November 20, 2016: Chinese Medical Sciences Journal, Chung-kuo i Hsüeh K'o Hsüeh Tsa Chih
https://www.readbyqxmd.com/read/28052185/early-administration-of-inhaled-corticosteroids-for-preventing-chronic-lung-disease-in-very-low-birth-weight-preterm-neonates
#6
REVIEW
Vibhuti S Shah, Arne Ohlsson, Henry L Halliday, Michael Dunn
BACKGROUND: Chronic lung disease (CLD) remains a common complication among preterm infants. There is increasing evidence that inflammation plays an important role in the pathogenesis of CLD. Due to their strong anti-inflammatory properties, corticosteroids are an attractive intervention strategy. However, there are growing concerns regarding short- and long-term effects of systemic corticosteroids. Theoretically, administration of inhaled corticosteroids may allow for beneficial effects on the pulmonary system with a lower risk of undesirable systemic side effects...
January 4, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28045978/cord-blood-acute-phase-reactants-predict-early-onset-neonatal-sepsis-in-preterm-infants
#7
Leena B Mithal, Hannah L Palac, Ram Yogev, Linda M Ernst, Karen K Mestan
BACKGROUND: Early onset sepsis (EOS) is a major cause of morbidity and mortality in preterm infants, yet diagnosis remains inadequate resulting in missed cases or prolonged empiric antibiotics with adverse consequences. Evaluation of acute phase reactant (APR) biomarkers in umbilical cord blood at birth may improve EOS detection in preterm infants with intrauterine infection. METHODS: In this nested case-control study, infants (29.7 weeks gestation, IQR: 27.7-32...
2017: PloS One
https://www.readbyqxmd.com/read/28034653/the-influence-of-interpregnancy-interval-on-infant-mortality
#8
David Mckinney, Melissa House, Aimin Chen, Louis Muglia, Emily Defranco
BACKGROUND: In Ohio the infant mortality rate is above the national average and the black infant mortality rate is more than twice the white infant mortality rate. Having a short interpregnancy interval has been shown to correlate with preterm birth and low birth weight, but the effect of short interpregnancy interval on infant mortality is less well established. OBJECTIVE: To quantify the population impact of interpregnancy interval on the risk of infant mortality...
December 26, 2016: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28007513/-delayed-umbilical-cord-clamping-in-preterm-infants-born-before-37%C3%A2-weeks-of-gestation-a-prospective-observational-study
#9
O Dicky, V Ehlinger, B Guyard-Boileau, C Assouline, C Arnaud, C Casper
INTRODUCTION AND OBJECTIVES: Many international studies have demonstrated that delayed umbilical cord clamping reduces neonatal morbidity. However, in France, delayed umbilical cord clamping is still not performed in many neonatal units. The aims of this study were to evaluate the feasibility of developing a protocol of delayed umbilical cord clamping in the maternity ward of the Toulouse university hospital and to evaluate the impact of this new protocol on neonatal mortality. METHODS: We conducted a prospective observational study including 123 preterm infants born before 37 weeks of gestation between June 2012 and June 2013 and hospitalized at birth...
December 19, 2016: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
https://www.readbyqxmd.com/read/28000379/rate-correlates-and-outcomes-of-repeat-pregnancy-in-hiv-infected-women
#10
M Floridia, E Tamburrini, G Masuelli, P Martinelli, A Spinillo, G Liuzzi, A Vimercati, S Alberico, A Maccabruni, C Pinnetti, V Frisina, S Dalzero, M Ravizza
OBJECTIVES: The aim of the study was to assess the rate, determinants, and outcomes of repeat pregnancies in women with HIV infection. METHODS: Data from a national study of pregnant women with HIV infection were used. Main outcomes were preterm delivery, low birth weight, CD4 cell count and HIV plasma viral load. RESULTS: The rate of repeat pregnancy among 3007 women was 16.2%. Women with a repeat pregnancy were on average younger than those with a single pregnancy (median age 30 vs...
December 21, 2016: HIV Medicine
https://www.readbyqxmd.com/read/27992071/are-behaviour-problems-in-extremely-low-birth-weight-children-related-to-their-motor-ability
#11
Marcella Danks, Kate Cherry, Yvonne R Burns, Peter H Gray
AIM: Investigate if behaviour problems are independently related to mild motor impairment in 11-13 year old children born preterm with extremely low birth weight (ELBW). METHODS: The cross sectional study included 48 (27 male) non-disabled, otherwise healthy ELBW children (<1000g) and 55 (28 male) term born peers. Parents reported behaviour using the Child Behavior Checklist (CBCL). Children completed the Movement Assessment Battery for Children (Movement ABC)...
December 19, 2016: Acta Paediatrica
https://www.readbyqxmd.com/read/27988045/multi-spacer-typing-as-an-effective-method-to-distinguish-the-clonal-lineage-of-clostridium-butyricum-strains-isolated-from-stool-samples-during-a-series-of-necrotizing-enterocolitis-cases
#12
S Benamar, N Cassir, V Merhej, P Jardot, C Robert, D Raoult, B La Scola
BACKGROUND: Necrotizing enterocolitis (NEC) is a devastating gastrointestinal disease with high morbidity and mortality that predominantly affects preterm neonates during outbreaks. In a previous study, the present authors identified 15 Clostridium butyricum isolates from stool samples during a series of NEC cases involving four neonatal intensive care units. A clonal lineage of these strains was observed by in-silico multi-locus sequence typing. AIM: To confirm the previous findings by sequencing a larger number of C...
November 14, 2016: Journal of Hospital Infection
https://www.readbyqxmd.com/read/27987395/randomised-controlled-trial-of-sustained-lung-inflation-for-resuscitation-of-preterm-infants-in-the-delivery-room
#13
Paveewan Jiravisitkul, Sasivimol Rattanasiri, Pracha Nuntnarumit
AIM: To compare the effects of sustained lung inflation (SLI) vs. standard resuscitation on physiologic responses of preterm infants during resuscitation. METHODS: Preterm infants (25-32 weeks gestational age) requiring positive-pressure ventilation or continuous positive airway pressure were randomly assigned to either the SLI group (SLI at 25cmH2O for 15s) or Non-SLI group (standard resuscitation alone). The heart rate (HR), oxygen saturation (SpO2), oxygen requirement, and intubation rate in the delivery room were evaluated...
February 2017: Resuscitation
https://www.readbyqxmd.com/read/27967287/early-therapy-services-following-neonatal-intensive-care-unit-discharge
#14
Odochi Nwabara, Cynthia Rogers, Terrie Inder, Roberta Pineda
AIMS: To (1) characterize early therapy services for preterm infants in the first two years of life, and (2) define factors related to accessing early therapy services. METHODS: Therapy utilization after discharge from the neonatal intensive care unit (NICU) was tracked in 57 infants born ≤30 weeks gestation from 2007 to 2010. Participants returned for developmental testing at two years. Factors related to early therapy utilization were explored. RESULTS: Fifty-two (91%) infants received a referral for therapy at NICU discharge but only 44 (77%) received at least one type of therapy during the first two years of life...
December 14, 2016: Physical & Occupational Therapy in Pediatrics
https://www.readbyqxmd.com/read/27941067/association-between-preterm-birth-and-lower-adult-height-in-women
#15
José G B Derraik, Maria Lundgren, Wayne S Cutfield, Fredrik Ahlsson
We examined whether being born preterm was associated with changes in adult anthropometry in women. We assessed data on 201,382 women (born in 1973-1988) from the Swedish Birth Register. The mean age was 26.0 years. Of the women in our cohort, 663 were born very preterm (<32 weeks of gestation), 8,247 were born moderately preterm (at least 32 weeks but <37 weeks), and 192,472 were born at term (37-41 weeks). Subgroup analyses were carried out among siblings and also after adjustment for maternal anthropometric data...
January 1, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/27939123/feeding-methods-at-discharge-predict-long-term-feeding-and-neurodevelopmental-outcomes-in-preterm-infants-referred-for-gastrostomy-evaluation
#16
Sudarshan R Jadcherla, Tanvi Khot, Rebecca Moore, Manish Malkar, Ish K Gulati, Jonathan L Slaughter
OBJECTIVE: To test the hypothesis that oral feeding at first neonatal intensive care unit discharge is associated with less neurodevelopmental impairment and better feeding milestones compared with discharge with a gastrostomy tube (G-tube). STUDY DESIGN: We studied outcomes for a retrospective cohort of 194 neonates <37 weeks' gestation referred for evaluation and management of feeding difficulties between July 2006 and July 2012. Discharge milestones, length of hospitalization, and Bayley Scales of Infant Development-Third Edition scores at 18-24 months were examined...
December 1, 2016: Journal of Pediatrics
https://www.readbyqxmd.com/read/27921517/effect-of-partial-compliance-on-the-prevention-of-recurrent-preterm-birth-in-women-receiving-weekly-17-alpha-hydroxyprogesterone-caproate-injections
#17
Ziad A Haidar, Hind N Moussa, Susan Hosseini Nasab, Baha M Sibai
PURPOSE: To analyze the effect of partial compliance on preterm birth (PTB) prevention among women with previous PTB and receiving 17 alpha-hydroxyprogesterone caproate (17-OHPC). STUDY DESIGN: This is a secondary analysis of a multicenter trial for the prevention of recurrent PTB. Women with prior PTB were randomly assigned between 15 0/7 and 20 3/7 weeks to weekly injections of either 17-OHPC or placebo. Full 100% compliance (group 1) was compared to 40-80% (group 2)...
December 6, 2016: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/27919059/role-of-maternal-occupational-physical-activity-and-psychosocial-stressors-on-adverse-birth-outcomes
#18
Laura J Lee, Elaine Symanski, Philip J Lupo, Sarah C Tinker, Hilda Razzaghi, Wenyaw Chan, Adrienne T Hoyt, Mark A Canfield
OBJECTIVES: We examined the association of an array of estimated maternal occupational physical activities and psychosocial stressors during pregnancy with odds for preterm birth (PTB) and small-for-gestational age (SGA). METHODS: Data for infants born without major birth defects delivered from 1997 to 2009 whose mothers reported working at least 1 month during pregnancy were obtained from the National Birth Defects Prevention Study. We linked occupational codes to the US Department of Labor's Occupational Information Network, which provides estimates of exposure for multiple domains of physical activity and psychosocial stressors by occupational categories...
October 6, 2016: Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/27918947/the-effect-of-blood-staining-on-cervicovaginal-quantitative-fetal-fibronectin-concentration-and-prediction-of-spontaneous-preterm-birth
#19
Natasha L Hezelgrave, Katy Kuhrt, Kate Cottam, Paul T Seed, Rachel M Tribe, Andrew H Shennan
OBJECTIVE: Spontaneous preterm birth is the leading cause of neonatal morbidity and mortality. Cervicovaginal fetal fibronectin (fFN) has enhanced prediction of preterm birth and, more recently, quantified results have become available so that management can planned more effectively and targeted to individual women. Manufacture guidelines stipulate that fetal fibronectin (fFN) samples should be discarded in the presence of moderate to heavy vaginal bleeding but there hasn't yet been any formal investigation into the effect of blood staining on fetal fibronectin concentration and subsequent preterm birth prediction...
January 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/27913060/outcome-of-pregnancy-and-neonatal-complications-with-anti-tumor-necrosis-factor-%C3%AE-use-in-females-with-immune-mediated-diseases-a-systematic-review-and-meta-analysis
#20
REVIEW
Fukiko Komaki, Yuga Komaki, Dejan Micic, Akio Ido, Atsushi Sakuraba
BACKGROUND: Immune mediated diseases such as rheumatoid arthritis (RA), ankylosing spondylitis (AS), and inflammatory bowel disease (IBD) commonly affect young and adolescent females. Anti-tumor necrosis factor (TNF)-α agents are increasingly used to treat these conditions, but their safety during pregnancy remains unclear. OBJECTIVES: To evaluate the risk of pregnancy related outcomes in patients with various immune mediated diseases treated with anti-TNF-α agents...
January 2017: Journal of Autoimmunity
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