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https://www.readbyqxmd.com/read/29451823/evaluation-of-fetal-intestinal-cell-growth-and-antimicrobial-biofunctionalities-of-donor-human-milk-after-preparative-processes
#1
Pasinee Kanaprach, Nutkridta Pongsakul, Nopporn Apiwattanakul, Chatchai Muanprasat, Sarayut Supapannachart, Pracha Nuntnarumit, Somchai Chutipongtanate
BACKGROUND: Donor human milk is considered the next best nutrition following mother's own milk to prevent neonatal infection and necrotizing enterocolitis in preterm infants who are admitted at neonatal intensive care unit. However, donor milk biofunctionalities after preparative processes have rarely been documented. OBJECTIVE: To evaluate biofunctionalities preserved in donor milk after preparative processes by cell-based assays. MATERIALS AND METHODS: Ten pools of donor milk were produced from 40 independent specimens...
February 16, 2018: Breastfeeding Medicine: the Official Journal of the Academy of Breastfeeding Medicine
https://www.readbyqxmd.com/read/29450194/avoiding-arterial-hypotension-in-preterm-neonates-ahip-a-single-center-randomised-controlled-study-investigating-simultaneous-near-infrared-spectroscopy-measurements-of-cerebral-and-peripheral-regional-tissue-oxygenation-and-dedicated-interventions
#2
Gerhard Pichler, Nina Höller, Nariae Baik-Schneditz, Bernhard Schwaberger, Lukas Mileder, Jasmin Stadler, Alexander Avian, Jasmin Pansy, Berndt Urlesberger
Introduction: Up to 50% of preterm infants admitted to intensive care units require cardiocirculatory support. The aim of the present study was to assess whether simultaneous monitoring of cerebral tissue oxygenation index (cTOI) and peripheral tissue oxygenation index (pTOI) using near-infrared spectroscopy (NIRS) in combination with dedicated intervention guidelines may help avoiding arterial hypotension and catecholamine administration in preterm neonates. Study design: Preterm neonates <37 weeks of gestation were included in a single center randomized controlled study...
2018: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/29447332/the-impact-of-the-maternal-foetal-environment-on-outcomes-of-surgery-for-congenital-heart-disease-in-neonates
#3
James William Gaynor, Samuel Parry, Julie S Moldenhauer, Rebecca A Simmons, Jack Rychik, Richard F Ittenbach, William W Russell, Erin Zullo, John Laurenson Ward, Susan C Nicolson, Thomas L Spray, Mark P Johnson
OBJECTIVES: Pregnancies with congenital heart disease in the foetus have an increased prevalence of pre-eclampsia, small for gestational age and preterm birth, which are evidence of an impaired maternal-foetal environment (MFE). METHODS: The impact of an impaired MFE, defined as pre-eclampsia, small for gestational age or preterm birth, on outcomes after cardiac surgery was evaluated in neonates (n = 135) enrolled in a study evaluating exposure to environmental toxicants and neuro-developmental outcomes...
February 13, 2018: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29442278/racial-ethnic-inequities-in-low-birth-weight-and-preterm-birth-the-role-of-multiple-forms-of-stress
#4
Joanna Almeida, Laia Bécares, Kristin Erbetta, Vani R Bettegowda, Indu B Ahluwalia
Introduction Racial/ethnic inequities in low birth weight (LBW) and preterm birth (PTB) persist in the United States. Research has identified numerous risk factors for adverse birth outcomes; however, they do not fully explain the occurrence of, or inequalities in PTB/LBW. Stress has been proposed as one explanation for differences in LBW and PTB by race/ethnicity. Methods Using the Pregnancy Risk Assessment Monitoring System (PRAMS) data from 2012 to 2013 for 21 states and one city (n = 15,915) we used Poisson regression to estimate the association between acute, financial and relationship stressors and LBW and PTB, and to examine the contribution of these stressors individually and simultaneously to racial/ethnic differences in LBW and PTB...
February 13, 2018: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/29417204/the-influence-of-gestational-age-mode-of-delivery-and-abdominal-wall-closure-method-on-the-surgical-outcome-of-neonates-with-uncomplicated-gastroschisis
#5
Maria V Fraga, Pablo Laje, William H Peranteau, Holly L Hedrick, Nahla Khalek, Juliana S Gebb, Julie S Moldenhauer, Mark P Johnson, Alan W Flake, N Scott Adzick
AIM OF THE STUDY: To evaluate if gestational age (GA), mode of delivery and abdominal wall closure method influence outcomes in uncomplicated gastroschisis (GTC). METHODS: Retrospective review of NICU admissions for gastroschisis, August 2008-July 2016. Primary outcomes were: time to start enteral feeds (on-EF), time to discontinue parenteral nutrition (off-PN), and length of stay (LOS). MAIN RESULTS: A total of 200 patients with GTC were admitted to our NICU...
February 7, 2018: Pediatric Surgery International
https://www.readbyqxmd.com/read/29404740/early-and-late-pregnancy-outcomes-in-women-treated-with-cold-coagulation-versus-lletz-cervical-treatment-for-cervical-intraepithelial-neoplasia-a-retrospective-cohort-study
#6
Dimitrios Papoutsis, Martyn Underwood, William Parry-Smith, Jane Panikkar
PURPOSE: To compare the pregnancy outcomes between women who were treated with cold-coagulation versus large loop excision of the transformation zone (LLETZ) for cervical intraepithelial neoplasia. METHODS: This was a retrospective cohort study of women who had a single cervical treatment between 2010 and 2011. We identified those women who had a singleton pregnancy subsequent to their cervical treatment until September 2017. Women with previous cervical treatment, previous miscarriage or preterm delivery were excluded...
February 5, 2018: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29390934/interpregnancy-interval-and-subsequent-pregnancy-outcomes-after-dilation-and-evacuation
#7
Melissa Kuwahara, Kelly Yamasato, Mary Tschann, Bliss Kaneshiro
We conducted this study to compare outcomes for pregnancies conceived ≤6 months after dilation and evacuation (D&E) with those conceived >6 months after D&E. This retrospective cohort study included women who underwent D&E (14-26 weeks) and were readmitted with a subsequent pregnancy. The primary outcome was the rate of preterm birth (<37 weeks). We identified 737 D&Es with 214 subsequent pregnancies. Outcomes were available for 85.5% of these pregnancies. Preterm birth <37 weeks occurred in 9...
February 1, 2018: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29381407/premature-birth-and-circadian-preference-in-young-adulthood-evidence-from-two-birth-cohorts
#8
Johan Björkqvist, Anu-Katriina Pesonen, Liisa Kuula, Hanna-Maria Matinolli, Aulikki Lano, Marika Sipola-Leppänen, Marjaana Tikanmäki, Dieter Wolke, Marjo-Riitta Järvelin, Johan G Eriksson, Sture Andersson, Marja Vääräsmäki, Kati Heinonen, Katri Räikkönen, Petteri Hovi, Eero Kajantie
A preference for eveningness (being a "night owl") and preterm birth (<37 weeks of gestation) are associated with similar adversities, such as elevated blood pressure, impaired glucose regulation, poorer physical fitness, and lower mood. Yet, it remains unclear if and how preterm birth is associated with circadian preference. The aim of this study was to assess this association across the whole gestation range, using both objective and subjective measurements of circadian preference. Circadian preference was measured among 594 young adults (mean age 24...
January 30, 2018: Chronobiology International
https://www.readbyqxmd.com/read/29380252/newborn-screening-guidelines-for-congenital-hypothyroidism-in-india-recommendations-of-the-indian-society-for-pediatric-and-adolescent-endocrinology-ispae-part-i-screening-and-confirmation-of-diagnosis
#9
M P Desai, R Sharma, I Riaz, S Sudhanshu, R Parikh, V Bhatia
The Indian Society for Pediatric and Adolescent Endocrinology has formulated locally relevant Clinical Practice Guidelines for newborn screening, diagnosis and management of primary congenital hypothyroidism (CH). RECOMMENDATIONS: Screening should be done for every newborn using cord blood, or postnatal blood, ideally at 48 to 72 h of age. On this screen sample, neonates with TSH > 20 mIU/L serum units (or >34 mIU/L for samples taken between 24 to 48 h of age) should be recalled for confirmation...
January 30, 2018: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/29373884/effect-of-progesterone-on-latent-phase-prolongation-in-patients-with-preterm-premature-rupture-of-membranes
#10
Fatemeh Abdali, Simin Taghavi, Shabnam Vazifekhah, Mohammad Naghavi Behzad, Mohammad Mirza Aghazadeh Attari
Preterm premature rupture of membranes (PPROM) is a condition leading to an increased risk of maternal and neonatal morbidity and mortality in pregnant women. To prevent this complication, some studies have proposed using prophylactic progesterone. However, due to lack of sufficient relevant data, there is still need for further studies in this regard. This study was performed to determine the effect of rectal progesterone on the latent phase and maternal and neonatal outcome variables in females with PPROM...
December 2017: Acta Medica Iranica
https://www.readbyqxmd.com/read/29371170/comparison-of-long-term-fertility-outcomes-after-myomectomy-relationship-with-number-of-fibroids-removed
#11
Shirley Shue, Milena Radeva, Tommaso Falcone
STUDY OBJECTIVE: To determine if the number of fibroids removed during myomectomy for symptomatic relief affects long-term fertility outcomes in reproductive aged women. DESIGN: Retrospective cohort survey study (Canadian Task Force classification II-2) SETTING: University hospital PATIENTS: One hundred forty-four patients who underwent myomectomy for symptomatic fibroids and attempted to conceive afterwards INTERVENTION: Questionnaire mailed to reproductive-aged women who received robotic, laparoscopic, or abdominal myomectomy MEASUREMENTS AND MAIN RESULTS: Patients with >6 fibroids removed were less likely to achieve pregnancy after myomectomy than patients with ≤6 fibroids removed (22...
January 22, 2018: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29370028/thrombocytopenia-as-a-risk-factor-for-retinopathy-of-prematurity
#12
Selim Sancak, Handan H Toptan, Tulin Gokmen Yildirim, Guner Karatekin, Fahri Ovali
PURPOSE: To study the association between thrombocytopenia and retinopathy of prematurity (ROP). METHODS: The case-control study was conducted on preterm newborns with ROP between January 2011 and January 2014, retrospectively. The patients were assigned into two groups: Cases required intervention and controls developed no or Stage I ROP. RESULTS: Eighty-one premature infants with Type I ROP were enrolled to the study with a mean gestational age of 27...
January 23, 2018: Retina
https://www.readbyqxmd.com/read/29367099/mid-gestational-changes-in-cervicovaginal-fluid-cytokine-levels-in-asymptomatic-pregnant-women-are-predictive-markers-of-inflammation-associated-spontaneous-preterm-birth
#13
Emmanuel Amabebe, David R Chapman, Victoria L Stern, Graham Stafford, Dilly O C Anumba
OBJECTIVES: Perturbation of the choriodecidual space before the onset of spontaneous preterm birth (sPTB) could lead to a concomitant rise in both cervicovaginal fluid (CVF) cytokine and fetal fibronectin (FFN), and assessing the concentrations of both markers could improve the prediction of sPTB (delivery before 37 completed weeks of gestation). Therefore, we prospectively determined mid-trimester changes in CVF cytokine and FFN concentrations, and their predictive capacity for sPTB in asymptomatic pregnant women...
January 10, 2018: Journal of Reproductive Immunology
https://www.readbyqxmd.com/read/29359987/disparities-in-postpartum-contraceptive-counseling-and-provision-among-mothers-of-preterm-infants
#14
Annie Dude, Melissa Matulich, Samantha Estevez, Lilly Y Liu, Lynn M Yee
OBJECTIVE: Use of effective contraception could be one method to decrease recurrent preterm birth by increasing intervals between pregnancies. We assessed correlates of contraceptive counseling and uptake among women who delivered preterm. MATERIALS AND METHODS: This is a retrospective cohort study of women who delivered live-born singletons or twins before 32 weeks' gestation. We assessed documented contraceptive counseling and method uptake by postpartum discharge, using inpatient medical records, and correlates of highly effective contraception uptake by the postpartum visit using outpatient records...
January 23, 2018: Journal of Women's Health
https://www.readbyqxmd.com/read/29343138/the-efficacy-of-myo-inositol-supplementation-to-prevent-gestational-diabetes-onset-a-meta-analysis-of-randomized-controlled-trials
#15
Jiang Xu, Shandong Ye
INTRODUCTION: The efficacy of myo-inositol supplementation to prevent gestational diabetes onset remains controversial. We conduct a systematic review and meta-analysis to explore the influence of myo-inositol supplementation on the incidence of gestational diabetes. METHODS: We search PubMed, Embase, Web of science, EBSCO, and Cochrane Library databases through November 2017 for randomized controlled trials (RCTs) assessing the effect of myo-inositol supplementation on gestational diabetes onset...
January 17, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29338857/obstetric-complications-after-frozen-versus-fresh-embryo-transfer-in-women-with-polycystic-ovary-syndrome-results-from-a-randomized-trial
#16
Bo Zhang, Daimin Wei, Richard S Legro, Yuhua Shi, Jing Li, Lin Zhang, Yan Hong, Gang Sun, Ting Zhang, Weiping Li, Zi-Jiang Chen
OBJECTIVE: To evaluate the effect of frozen embryo transfer on maternal and neonatal complications of singleton and twin pregnancies compared with fresh embryo transfer in women with polycystic ovary syndrome (PCOS). DESIGN: A secondary analysis of a multicenter, randomized, controlled trial comparing live birth after frozen vs. fresh embryo transfer (FreFro-PCOS). SETTING: Reproductive medicine centers. PATIENT(S): A total of 1,508 patients with a diagnosis of PCOS who were undergoing IVF were enrolled...
January 12, 2018: Fertility and Sterility
https://www.readbyqxmd.com/read/29330315/outcome-of-preterm-infants-with-postnatal-cytomegalovirus-infection
#17
Julia Gunkel, Linda S de Vries, Marian Jongmans, Corine Koopman-Esseboom, Ingrid C van Haastert, Maria C J Eijsermans, Carolien van Stam, Bert G A van Zanten, Tom F W Wolfs, Joppe Nijman
OBJECTIVES: To assess whether preterm infants with postnatal cytomegalovirus infection develop neurologic sequelae in early childhood. METHODS: Infants <32 weeks' gestation were prospectively screened for cytomegalovirus (CMV) at term-equivalent age. Neurodevelopment was compared between CMV-positive and CMV-negative infants by using the Griffiths Mental Development Scales (GMDS) at 16 months' corrected age (CA); the Bayley Scales of Infant and Toddler Development, Third Edition or the GMDS at 24 to 30 months' CA; and the Wechsler Preschool and Primary Scale of Intelligence, Third Edition and Movement Assessment Battery for Children, Second Edition at 6 years of age...
February 2018: Pediatrics
https://www.readbyqxmd.com/read/29324613/racial-disparities-in-adverse-pregnancy-outcomes-and-psychosocial-stress
#18
William A Grobman, Corette B Parker, Marian Willinger, Deborah A Wing, Robert M Silver, Ronald J Wapner, Hyagriv N Simhan, Samuel Parry, Brian M Mercer, David M Haas, Alan M Peaceman, Shannon Hunter, Pathik Wadhwa, Michal A Elovitz, Tatiana Foroud, George Saade, Uma M Reddy
OBJECTIVE: To assess the relationships between self-reported psychosocial stress and preterm birth, hypertensive disease of pregnancy, and small-for-gestational-age (SGA) birth and to assess the extent to which these relationships account for racial and ethnic disparities in these adverse outcomes. METHODS: Self-reported measures of psychosocial stress (perceived stress, depression, racism, anxiety, resilience, and social support) were collected during pregnancy among a racially and ethnically diverse cohort of women enrolled in a prospective observational study of nulliparous women with singleton pregnancies, from eight clinical sites across the United States, between October 2010 and May 2014...
February 2018: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29309921/outcomes-of-pregnancies-achieved-by-double-gamete-donation-a-comparison-with-pregnancies-obtained-by-oocyte-donation-alone
#19
Lise Preaubert, Aurélie Vincent-Rohfritsch, Pietro Santulli, Vanessa Gayet, François Goffinet, Camille Le Ray
OBJECTIVE: Women increasingly resort to oocyte donation to become pregnant. The high risk of preeclampsia found in oocyte donation pregnancies and the separate risk of preeclampsia associated with sperm donation may be cumulative in double donation pregnancies. We aimed to study the obstetrical and perinatal outcomes of pregnancies obtained by double donation (both oocyte and sperm) in comparison with those obtained by oocyte donation alone (oocyte donation and partner's sperm). STUDY DESIGN: This cohort study included all women aged 43 and older who became pregnant after oocyte donation and gave birth between 2010 and 2016 in a tertiary maternity center...
December 15, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29304544/obstetric-history-and-likelihood-of-preterm-birth-of-twins
#20
Sarah Rae Easter, Sarah E Little, Julian N Robinson, Hector Mendez-Figueroa, Suneet P Chauhan
OBJECTIVE:  The objective of this study was to investigate the relationship between preterm birth in a prior pregnancy and preterm birth in a twin pregnancy. STUDY DESIGN:  We performed a secondary analysis of a randomized controlled trial evaluating 17-α-hydroxyprogesterone caproate in twins. Women were classified as nulliparous, multiparous with a prior term birth, or multiparous with a prior preterm birth. We used logistic regression to examine the odds of spontaneous preterm birth of twins before 35 weeks according to past obstetric history...
January 5, 2018: American Journal of Perinatology
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