Read by QxMD icon Read


Cinta Moraleda, Rachid Benmessaoud, Jessica Esteban, Yuly López, Hassan Alami, Amina Barkat, Tligui Houssain, Meryem Kabiri, Rachid Bezad, Saad Chaacho, Lola Madrid, Jordi Vila, Carmen Muñoz-Almagro, Jordi Bosch, Sara M Soto, Quique Bassat
PURPOSE: Group B streptococcus (GBS) is an important cause of neonatal sepsis worldwide. Data on the prevalence of maternal GBS colonization, risk factors for carriage, antibiotic susceptibility and circulating serotypes are necessary to tailor adequate locally relevant public health policies. METHODOLOGY: A prospective study including pregnant women and their newborns was conducted between March and July 2013 in Morocco. We collected clinical data and vagino-rectal and urine samples from the recruited pregnant women, together with the clinical characteristics of, and body surface samples from, their newborns...
March 15, 2018: Journal of Medical Microbiology
Lola Madrid, Rosauro Varo, Sonia Maculuve, Tacilta Nhampossa, Carmen Muñoz-Almagro, Enrique J Calderón, Cristina Esteva, Carla Carrilho, Mamudo Ismail, Begoña Vieites, Vicente Friaza, María Del Carmen Lozano-Dominguez, Clara Menéndez, Quique Bassat
BACKGROUND: Congenital cytomegalovirus (cCMV) infection is the most prevalent congenital infection acquired worldwide, with higher incidence in developing countries and among HIV-exposed children. Less is known regarding vertical transmission of parvovirus B19 (B19V) and enterovirus (EV). We aimed to assess the prevalence of CMV, B19V and EV vertical transmission and compare results of screening of congenital CMV obtained from two different specimens in a semirural Mozambican maternity...
2018: PloS One
Matthew Graham, Jonathan E Suk, Saki Takahashi, C Jessica Metcalf, Adela Paez Jimenez, Vladimir Prikazsky, Matthew J Ferrari, Justin Lessler
We report on and evaluate the process and findings of a real-time modeling exercise in response to an outbreak of measles in Lola prefecture, Guinea, in early 2015 in the wake of the Ebola crisis. Multiple statistical methods for the estimation of the size of the susceptible (i.e., unvaccinated) population were applied to weekly reported measles case data on seven subprefectures throughout Lola. Stochastic compartmental models were used to project future measles incidence in each subprefecture in both an initial and a follow-up iteration of forecasting...
March 12, 2018: American Journal of Tropical Medicine and Hygiene
Melissa Henry, Zeev Rosberger, Lola E Ianovski, Michael Hier, Anthony Zeitouni, Karen Kost, Alex Mlynarek, Martin Black, Christina MacDonald, Keith Richardson, Fabienne Fuhrmann, Gabrielle Chartier, Saul Frenkiel
OBJECTIVE: The primary purpose of this study was to identify predictors of Major Depressive Disorder in head and neck cancer (HNC) patients in the immediate post-treatment period (i.e., at three months post-diagnosis), with a focus on previously unexamined historical and contextual factors. METHODS: Prospective longitudinal study of 223 consecutive adults (72% participation) newly diagnosed with a first occurrence of primary HNC, including validated psychometric measures, Structured Clinical Interviews for DSM Disorders, and medical chart reviews...
March 13, 2018: Psycho-oncology
Danielle Bloch, Kenya Murray, Eric Peterson, Stephanie Ngai, Inessa Rubinstein, Tanya A Halse, Ifeoma Ezeoke, Laura Miller, Lola Arakaki, Arianne Ramautar, Mike Antwi, Paula Del Rosso, Marie Dorsinville, Sandhya Clark, Megan Halbrook, Joseph Kennedy, Sarah Braunstein, Don Weiss
Backgroun: d The case fatality rate (CFR) from invasive meningococcal disease (IMD) in New York City (NYC) is greater than national figures, with higher rates among females than males across all age groups. Methods: We conducted a retrospective cohort study among 151 persons aged 15 years and older diagnosed with IMD in NYC during 2008-2016 identified through communicable disease surveillance. We examined demographic, clinical, and community-level associations with death to confirm the elevated risk of mortality among female IMD patients after adjusting for confounders and to determine factors associated with female IMD mortality...
March 2, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Casey R Shillam, Lola MacLean
As the largest segment of the health care workforce, nurses have the greatest potential for advancing systems and services to improve health care delivery in the United States. This article presents a framework for nurse administrators to use in developing direct care nurses in their leadership influence competency as a means of increasing their advocacy potential. A systematic review resulted in establishing a nurse leadership influence framework based on the Kouzes and Posner leadership model. The framework includes leadership competencies by nursing professional organizations and was validated by 2 national nurse leader focus groups...
April 2018: Nursing Administration Quarterly
Zvi Granot, Maya Gershkovitz, Yaki Caspi, Tanya Fainsod-Levi, Ben Katz, Janna Michaeli, Saleh Khawaled, Shaya Lev, Lola Polyansky, Merav E Shaul, Ronit Vogt Sionov, Leonor Cohen-Daniel, Rami I Aqeilan, Yoav Shaul, Yasuo Mori, Rotem Karni, Zvi G Fridlender, Alexander M Binshtok
Neutrophils play a critical role in cancer, with both pro- and anti-tumor neutrophil subpopulations reported. The anti-tumor neutrophil subpopulation has the capacity to kill tumor cells and limit metastatic spread, yet not all tumor cells are equally susceptible to neutrophil cytotoxicity. Since cells that evade neutrophils have greater chances of forming metastases, we explored the mechanism neutrophils employ to kill tumor cells. Neutrophil cytotoxicity was previously shown to be mediated by secretion of H2O2...
February 28, 2018: Cancer Research
Michael H Charlton, Rihards Aleksis, Adélaïde Saint-Leger, Arya Gupta, Einars Loza, Lluís Ribas de Pouplana, Ilze Kaula, Daina Gustina, Marina Madre, Daina Lola, Kristaps Jaudzems, Grace Edmund, Christopher P Randall, Louise Kime, Alex J O'Neill, Wil Goessens, Aigars Jirgensons, Paul W Finn
N -Leucinyl benzenesulfonamides have been discovered as a novel class of potent inhibitors of E. coli leucyl-tRNA synthetase. The binding of inhibitors to the enzyme was measured by using isothermal titration calorimetry. This provided information on enthalpy and entropy contributions to binding, which, together with docking studies, were used for structure-activity relationship analysis. Enzymatic assays revealed that N -leucinyl benzenesulfonamides display remarkable selectivity for E. coli leucyl-tRNA synthetase compared to S...
February 8, 2018: ACS Medicinal Chemistry Letters
Lola Butcher
Episode payments for maternity care, however, are particularly challenging for many reasons, including the fact that a full course of care starts with one patient and usually ends with at least two. Something needs to be done, because pregnancy, labor, and birth account for seven of the top 20 most expensive hospitalized conditions.
February 2018: Managed Care
Kieran A Bates, Frances C Clare, Simon O'Hanlon, Jaime Bosch, Lola Brookes, Kevin Hopkins, Emilia J McLaughlin, Olivia Daniel, Trenton W J Garner, Matthew C Fisher, Xavier A Harrison
Host-associated microbes are vital for combatting infections and maintaining health. In amphibians, certain skin-associated bacteria inhibit the fungal pathogen Batrachochytrium dendrobatidis (Bd), yet our understanding of host microbial ecology and its role in disease outbreaks is limited. We sampled skin-associated bacteria and Bd from Pyrenean midwife toad populations exhibiting enzootic or epizootic disease dynamics. We demonstrate that bacterial communities differ between life stages with few shared taxa, indicative of restructuring at metamorphosis...
February 15, 2018: Nature Communications
Zaheer Ali, Anik Islam, Peter Sherrell, Mark Le-Moine, Georgios Lolas, Konstantinos Syrigos, Mehrdad Rafat, Lasse D Jensen
Therapeutic induction of blood vessel growth (angiogenesis) in ischemic tissues holds great potential for treatment of myocardial infarction and stroke. Achieving sustained angiogenesis and vascular maturation has, however, been highly challenging. Here we demonstrate that collagen:alginate hydrogels containing therapeutic, pro-angiogenic FGF-2, and formulated as microspheres, is a promising and clinically relevant vehicle for therapeutic angiogenesis. By titrating the amount of readily dissolvable and degradable collagen with more slowly degradable alginate in the hydrogel mixture, the degradation rates of the biomaterial controlling the release kinetics of embedded pro-angiogenic FGF-2 can be adjusted...
February 15, 2018: Biology Open
Ó Dembilio, Pilar Moya, Sandra Vacas, Lola Ortega-García, Enrique Quesada-Moraga, Josep A Jaques, Vicente Navarro-Llopis
BACKGROUND: A new Beauveria bassiana-based Attract and Infect Device (AID) to control Rhynchophorus ferrugineus Olivier (Coleoptera: Curculionidae) was developed. The virulence and persistence of the fungal formulation used in the AID was evaluated in laboratory. Semi-field and field trials were carried out to validate results and establish the potential of this device as a control tool. RESULTS: In laboratory conditions, an LT50 of 4.33 days was obtained when adults (7-10 day-old) were exposed to the Inoculation Tunnel (IT) containing 1 × 1010 conidia/g in an oil-based fungal formulation...
February 9, 2018: Pest Management Science
Priyesh N Patel, Alicia M Stafford, James R Patrinely, Derek K Smith, Justin H Turner, Paul T Russell, Kyle D Weaver, Lola B Chambless, Rakesh K Chandra
Objective To determine the factors associated with intra- and postoperative cerebrospinal fluid (CSF) leaks in setting of endoscopic transsphenoidal sellar surgery. Study Design Retrospective cohort. Setting Tertiary referral center. Subjects and Methods This study included 806 patients who underwent endoscopic transsphenoidal sellar surgery between 2004 and 2016. The associations between CSF leaks (intra- and postoperative) and patient demographics, medical history, tumor characteristics, and intraoperative repair techniques were analyzed...
January 1, 2018: Otolaryngology—Head and Neck Surgery
Thomas Kister, Johannes H M Maurer, Lola Gonzalez-Garcia, Tobias Kraus
Metal grids with sub-micron diameters are optically transparent, mechanically flexible, and suitable materials for transparent and flexible electronics. Printing such narrow lines with dilute metal nanoparticle inks is challenging because it requires percolation throughout the particle packing. Here, we print fully connected sub-micron lines of 3.2 nm diameter gold nanoparticles and vary the organic ligand shell to study the relation between colloidal interactions, ligand binding to the metal core, and conductivity of the printed lines...
February 5, 2018: ACS Applied Materials & Interfaces
Jennifer Verbrugge, Malia Rumbaugh, Lola Cook, Jeanine Schulze, Mandy Miller, Laura Heathers, Vanessa Arnedo, Maggie McGuire Kuhl, Tatiana Foroud
Facebook advertising is a powerful tool for increasing the outreach and recruitment of research participants. We describe our experience as genetic counselors within the context of an internet-based research study, recruiting subjects for a Parkinson disease (PD) biomarker study.
February 2, 2018: Journal of Genetic Counseling
Lola Giusti, Jamie Jenkins, Mitchell A Goodis, Carsen Bentley, Christine E Miller, Alexander Faigen
The use of methamphetamines is a significant public health concern not only in America but worldwide. The consequences of this drug's use are widespread, having major physiologic and psychological effects that are damaging to users' bodies and well-being. Meth use wreaks havoc on one's oral health, with the effects including demineralization of tooth surfaces, carious lesions, inflammation of the periodontium, and more. In addition to examining the neurotoxic effects that methamphetamines have on the brain, this article will discuss how dental professionals can approach treatment of individuals who are affected by this debilitating drug, utilizing a strategy that combines caries arrest with oral hygiene improvement and disease prevention...
February 2018: Compendium of Continuing Education in Dentistry
Rebecca L Gunter, Sara Fernandes-Taylor, Shahrose Rahman, Lola Awoyinka, Kyla M Bennett, Sharon M Weber, Caprice C Greenberg, K Craig Kent
BACKGROUND: Surgical site infection (SSI) is the most common nosocomial infection and the leading cause of readmission among surgical patients. Many SSIs develop in the postdischarge period and are inadequately recognized by patients. To address this, we developed a mobile health protocol of remote wound monitoring using smartphone technology. The current study aims to establish its feasibility among patients and providers. STUDY DESIGN: We enrolled vascular surgery patients during their inpatient stay...
January 19, 2018: Journal of the American College of Surgeons
Edouard Gardan, Lola Jacquemont, Christophe Perret, Pierre-Marie Heudes, Pierre-Antoine Gourraud, Maryvonne Hourmant, Eric Frampas, Sophie Limou
BACKGROUND: CT volumetry has previously been proposed as an alternative to scintigraphy for the evaluation of pre-donation split renal function and the prediction of post-donation renal function in living kidney donors. The aim of our study was to retrospectively assess the relevance of three CT volumetry techniques for estimating pre-donation kidney function and predicting the risk for chronic kidney disease (CKD) at 1-year post-nephrectomy in a French cohort of living donors using isotopic measures of kidney function...
February 2018: European Journal of Radiology
Rosauro Varo, Valerie M Crowley, Antonio Sitoe, Lola Madrid, Lena Serghides, Kevin C Kain, Quique Bassat
BACKGROUND: Despite recent efforts and successes in reducing the malaria burden globally, this infection still accounts for an estimated 212 million clinical cases, 2 million severe malaria cases, and approximately 429,000 deaths annually. Even with the routine use of effective anti-malarial drugs, the case fatality rate for severe malaria remains unacceptably high, with cerebral malaria being one of the most life-threatening complications. Up to one-third of cerebral malaria survivors are left with long-term cognitive and neurological deficits...
January 24, 2018: Malaria Journal
Lisa R Hirschhorn, Lola Adedokun, Abdul Ghaffar
No abstract text is available yet for this article.
December 21, 2017: BMC Health Services Research
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"