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https://www.readbyqxmd.com/read/29027960/a-new-approach-to-assess-lifetime-dietary-patterns-finds-lower-consumption-of-animal-foods-with-aging-in-a-longitudinal-analysis-of-a-health-oriented-adventist-population
#1
Marcia C T Martins, Karen Jaceldo-Siegl, Michael Orlich, Jing Fan, Andrew Mashchak, Gary E Fraser
Life-course diet patterns may impact risk of disease, but little is known about dietary trends with aging. In a retrospective longitudinal analysis we estimated lifetime intake of animal products and adherence to vegetarian dietary patterns among 51,082 Adventist Health Study-2 (AHS-2) subjects using data from a reliable life-course dietary (meats, dairy, eggs) questionnaire. Results showed a marked tendency to consume fewer animal products (in total) in older years and to reduce consumption of meat, poultry and fish, but not eggs or dairy...
October 13, 2017: Nutrients
https://www.readbyqxmd.com/read/28992039/environmental-causation-of-turtle-scute-anomalies-in-ovo-and-in-silico
#2
Roland Zimm, Blair P Bentley, Jeanette Wyneken, Jacqueline E Moustakas-Verho
The turtle shell is often described as an evolutionary novelty that facilitated the radiation of the clade Testudines. The scutes, or keratinous plates, of the turtle shell are hypothesized to be patterned by reaction-diffusion dynamics, and this property of their development provides explanatory power to mechanisms of anomalous variation. A mathematical model of scute development predicts that anomalous variation in the phylogenetically stable pattern of scutes is achieved by environmental influence on the developmental program...
July 25, 2017: Integrative and Comparative Biology
https://www.readbyqxmd.com/read/28990230/response-of-in-ovo-administration-of-zinc-on-egg-hatchability-and-immune-response-of-commercial-broiler-chicken
#3
N Jose, A V Elangovan, V B Awachat, D Shet, J Ghosh, C G David
An experiment was conducted to determine the effect of in ovo administration of different forms of zinc with respect to hatchability and performance of commercial broiler chicken. In trial 1, the fertile eggs on day 18 were divided into six treatment groups: Group I as control without any supplementation of zinc, group II to IV were supplemented with 0.5 mg zinc per egg as zinc sulphate, zinc methionine or nano zinc, respectively, and Group V with nano zinc at 0.25 mg zinc per egg. Sixth group received 0...
October 8, 2017: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/28988845/a-bombyx-homolog-of-ovo-is-a-segmentation-gene-that-acts-downstream-of-bm-wnt1-bombyx-wnt1-homolog
#4
Hajime Nakao
Insect embryogenesis is divided into long and short/intermediate germ types. The long germ type may exhibit Drosophila-like hierarchical segmentation mechanisms, whereas the short/intermediate type assumes some repeating mechanisms that are considered to be ancestral. Embryogenesis in Bombyx mori possesses both characteristics. Here, Bombyx ovo homolog (Bm-ovo) was identified as a gene involved in segmentation. Ovo is a Drosophila gene that encodes a zinc finger transcription factor and studies on its homolog functions in other systems have suggested that it acts as a switch to enable the initiation of differentiation from a progenitor cell state...
October 5, 2017: Gene Expression Patterns: GEP
https://www.readbyqxmd.com/read/28986936/in-ovo-feeding-of-creatine-pyruvate-modulates-growth-performance-energy-reserves-and-mrna-expression-levels-of-gluconeogenesis-and-glycogenesis-enzymes-in-liver-of-embryos-and-neonatal-broilers
#5
M M Zhao, D Q Gong, T Gao, L Zhang, J L Li, P A Lv, L L Yu, F Gao, G H Zhou
The effects of in ovo feeding (IOF) of creatine pyruvate (CrPyr) on the growth performance, energy reserves and mRNA expression levels of gluconeogenesis and glycogenesis enzymes in liver of late-term embryos and neonatal broilers were investigated. After candling on 16 day of incubation, a total of 960 eggs were randomly assigned to three treatments: (i) non-injected control, (ii) saline group injected with 0.6 ml of 0.75% physiological saline and (iii) Creatine pyruvate group injected with 0.6 ml of physiological saline containing 12 mg CrPyr/egg...
October 7, 2017: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/28982681/early-neonatal-loss-of-inhibitory-synaptic-input-to-the-spinal-motor-neurons-confers-spina-bifida-like-leg-dysfunction-in-a-chicken-model
#6
Md Sakirul Islam Khan, Hiroaki Nabeka, Farzana Islam, Tetsuya Shimokawa, Shouichiro Saito, Xuan Li, Soichiro Kawabe, Fumihiko Hamada, Tetsuya Tachibana, Seiji Matsuda
Spina bifida aperta (SBA), one of the most common congenital malformations, causes lifelong neurological complications particularly in terms of motor dysfunction. Fetuses with SBA exhibit voluntary leg movements in utero and during early neonatal life but these disappear within the first few weeks after birth. However, the pathophysiological sequence underlying such motor dysfunction remains unclear. Additionally, because important insights have yet to be obtained from human cases, an appropriate animal model is essential...
October 5, 2017: Disease Models & Mechanisms
https://www.readbyqxmd.com/read/28973883/heterochronic-truncation-of-odontogenesis-in-theropod-dinosaurs-provides-insight-into-the-macroevolution-of-avian-beaks
#7
Shuo Wang, Josef Stiegler, Ping Wu, Cheng-Ming Chuong, Dongyu Hu, Amy Balanoff, Yachun Zhou, Xing Xu
Beaks are innovative structures characterizing numerous tetrapod lineages, including birds, but little is known about how developmental processes influenced the macroevolution of these important structures. Here we provide evidence of ontogenetic vestigialization of alveoli in two lineages of theropod dinosaurs and show that these are transitional phenotypes in the evolution of beaks. One of the smallest known caenagnathid oviraptorosaurs and a small specimen of the Early Cretaceous bird Sapeornis both possess shallow, empty vestiges of dentary alveoli...
September 25, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28960745/real-world-mri-experience-with-non-conditional-and-conditional-cardiac-rhythm-devices-after-magnasafe
#8
Steve Mason, Jeffrey S Osborn, Ritesh Dhar, Allison Tonkin, Jon-David Ethington, Viet Le, Jose Benuzillo, Donald L Lappe, Kirk U Knowlton, T Jared Bunch, Jeffrey L Anderson
INTRODUCTION: The recent MagnaSafe Registry demonstrated safety of non-thoracic magnetic resonance imaging (MRI) with non-conditional cardiac implantable electronic devices (CIEDs). However, independent validation and extension to thoracic MRIs are needed. METHODS AND RESULTS: We prospectively examined 178 consecutive patients with CIEDs who underwent 212 MRI scans (62 with implantable cardioverter/defibrillators) for clinical reasons between February 2014 and August 2016...
September 28, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28957713/ovo-vegetarian-diet-is-associated-with-lower-systemic-blood-pressure-in-taiwanese-women
#9
C P Ho, J H Yu, T J F Lee
OBJECTIVE: This study was designed to investigate blood pressure (BP) profiles among Taiwanese women with different dietary patterns. STUDY DESIGN: Cross-sectional study. METHODS: A total of 269 non-hypertensive Taiwanese women, 40 years of age or older, were surveyed using structured questionnaires, and measurements of BP and physiological parameters were made. To assess differences among vegans, ovo-vegetarians, and meat eaters in terms of BP, demographic, and health behavior data, the chi-squared and Fisher's exact tests were employed for categorical variables, and analysis of variance and independent t-tests were performed for continuous variables...
September 25, 2017: Public Health
https://www.readbyqxmd.com/read/28957008/immunity-elicited-by-a-turkey-herpesvirus-vectored-newcastle-disease-vaccine-in-turkey-against-challenge-with-a-recent-genotype-iv-newcastle-disease-virus-field-strain
#10
Abderrazak El Khantour, Sami Darkaoui, Tímea Tatár-Kis, Tamás Mató, Amal Essalah-Bennani, Christophe Cazaban, Vilmos Palya
Newcastle disease (ND) is still a major poultry disease worldwide. Vaccination remains the principal method of controlling ND in endemic countries. Various vaccination strategies, including the use of recently developed recombinant vaccines, have been used to control it. Recombinant vaccines that use the herpesvirus of turkey (HVT) as a vector to express one of the key antigens of Newcastle disease virus (NDV) have been developed to overcome some of the drawbacks related to the use of conventional vaccines...
September 2017: Avian Diseases
https://www.readbyqxmd.com/read/28953094/combined-use-of-in-ovo-electroporation-and-cultured-neurons-for-gene-function-analysis-of-embryogenesis-in-the-chicken-optic-tectum
#11
Ciqing Yang, Xiaoying Li, Qiuling Li, Bichao Zhang, Han Li, Juntang Lin
Chicken embryos are used widely in the fields of developmental biology and neurobiology. The chicken embryo also serves as a model to analyze gene expression and function using in ovo electroporation. Plasmids may be injected into the spinal cord or tectum of the chicken central nervous system by microinjection for electroporation. Here, we developed a novel method that combines in ovo electroporation and neuronal culturing to study gene function in the chicken tectum during embryo development. Our method can be used to study in-vivo and in-vitro exogenous genes' function...
September 25, 2017: Neuroreport
https://www.readbyqxmd.com/read/28951326/developmental-roles-of-the-spontaneous-depolarization-wave-in-synaptic-network-formation-in-the-embryonic-brainstem
#12
Yoko Momose-Sato, Katsushige Sato
One of the earliest activities expressed within the developing central nervous system is a widely propagating wave-like activity, which we referred to as the depolarization wave. Despite considerable consensus concerning the global features of the activity, its physiological role is yet to be clarified. The depolarization wave is expressed during a specific period of functional synaptogenesis, and this developmental profile has led to the hypothesis that the wave plays some roles in synaptic network organization...
September 23, 2017: Neuroscience
https://www.readbyqxmd.com/read/28934691/the-role-of-ppar-alpha-in-perfluorooctanoic-acid-induced-developmental-cardiotoxicity-and-l-carnitine-mediated-protection-results-of-in-ovo-gene-silencing
#13
Meng Zhao, Qixiao Jiang, Min Geng, Li Zhu, Yunqiu Xia, Aashish Khanal, Chunbo Wang
Perfluorooctanoic acid (PFOA) is a persistent organic pollutant. This study established an in ovo peroxisome proliferator-activated receptor alpha (PPAR alpha) silencing model in chicken embryo heart, and investigated the role of PPAR alpha in PFOA induced developmental cardiotoxicity. The in ovo silencing was achieved by introducing lentivirus expressing PPAR alpha siRNA into ED2 chicken embryo via microinjection (0.05ul/g egg weight). Transfection efficacy was confirmed by fluorescent microscopy and western blotting...
September 14, 2017: Environmental Toxicology and Pharmacology
https://www.readbyqxmd.com/read/28929578/horizontal-transfer-of-mir-23a-from-hypoxic-tumor-cell-colonies-can-induce-angiogenesis
#14
T V Sruthi, Lincy Edatt, Grace R Raji, Haritha K, S Sharath Shankar, Vandana Shankar, Vishnu R, Aswini P, V B Sameer Kumar
Neo vessel formation by angiogenesis is an important event during many pathological conditions including cancer, where it is indispensable for tumor growth and survival. Although, various pro-angiogenic cytokines and soluble factors, secreted by tumor cells, have been reported to promote angiogenesis, recent studies have shown regulatory role of exosomes, secreted by tumor cells in the process of angiogenesis. These exosomes are capable of carrying nucleic acids, proteins etc. as their cargo. Under the light of these facts and considering the presence of miRNAs, the non-coding RNAs capable of regulating target gene expression, as one of the major cargos in the exosomes, we investigated, whether exosomes derived from normoxic and hypoxic tumor cell colonies exhibit difference in levels of miR-23∼27∼24 cluster members and if so, to check the significance of their horizontall transfer on the process of angiogenesis...
September 20, 2017: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/28916308/transient-transfection-of-cryptosporidium-baileyi
#15
A-K Tetens, S Hanig, M Kurth, G Greif, R Entzeroth
Here we demonstrate the transient transfection of C. baileyi. We describe the transfection of this apicomplexan parasite and the cultivation in ovo. The functionality of heterologous sequences in C. baileyi was demonstrated by the expression and detection of the mCherry protein in ovo. The mCherry protein was expressed in parasitic stages up to the oocyst stage under the control of the heterologous promoter region of the C. parvum actin gene.
September 12, 2017: Parasitology International
https://www.readbyqxmd.com/read/28899664/implant-for-autologous-soft-tissue-reconstruction-using-an-adipose-derived-stem-cell-colonized-alginate-scaffold
#16
Tobias Hirsch, Christine Laemmle, Bjoern Behr, Marcus Lehnhardt, Frank Jacobsen, Dirk Hoefer, Maximilian Kueckelhaus
BACKGROUND: Adipose-derived stem cells represent an interesting option for soft tissue replacement as they are easy to procure and can generate their own blood supply through the production of angiogenic factors. We seeded adipose-derived stem cells on a bioresorbable, biocompatible polymer alginate scaffold to generate autologous soft tissue constructs for repair. MATERIALS AND METHODS: We built and optimized an alginate scaffold and tested its biocompatibility using the MTT assay and its hydration capacity...
August 16, 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/28892018/antioxidant-artemisia-princeps-extract-enhances-the-expression-of-filaggrin-and-loricrin-via-the-ahr-ovol1-pathway
#17
Akiko Hirano, Masashi Goto, Tsukasa Mitsui, Akiko Hashimoto-Hachiya, Gaku Tsuji, Masutaka Furue
The Japanese mugwort, Artemisia princeps (yomogi in Japanese), has anti-inflammatory and antioxidant effects. Skin care products containing Artemisia princeps extract (APE) are known to improve dry skin symptoms in atopic dermatitis. Atopic dry skin is associated with a marked reduction of skin barrier proteins, such as filaggrin (FLG) and loricrin (LOR). Recently, aryl hydrocarbon receptor (AHR), and its downstream transcription factor OVO-like 1 (OVOL1), have been shown to regulate the gene expression of FLG and LOR...
September 11, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28881299/photo-responsive-tetraether-lipids-based-vesicles-for-prophyrin-mediated-vascular-targeting-and-direct-phototherapy
#18
Gihan Mahmoud, Jarmila Jedelská, Boris Strehlow, Samia Omar, Marc Schneider, Udo Bakowsky
Tetraether lipids (TELs) derived from the thermoacidophilic archaeon Sulfolobus acidocaldarius are dominated by polyisoprenoid skeleton. The unique molecular stability of TELs is attributed to the presence of cyclopentane rings, methyl side groups and sugar residues that create extensive hydrogen bond network. In addition, the presence of ether linkages and the lacking of double bonds make them an epitome candidate for photodynamic therapy (PDT). A subtle blend of formulation design to trigger efficient photo responses of protoporphyrin IX (PpIX) exploiting TELs was developed...
August 30, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28880894/in-ovo-and-dietary-administration-of-oligosaccharides-extracted-from-palm-kernel-cake-influence-general-health-of-pre-and-neonatal-broiler-chicks
#19
Mohammad Faseleh Jahromi, Parisa Shokryazdan, Zulkifli Idrus, Rohollah Ebrahimi, Juan Boo Liang
Palm kernel cake (PKC) is the main byproduct from the palm oil industry in several tropical countries that contains considerable amounts of oligosaccharide. We earlier demonstrated beneficial prebiotic effects of oligosaccharides extract of PKC (OligoPKC) in starter and finisher broiler birds. This study was envisaged to elucidate the effects of in ovo and/or oral administration of the OligoPKC on prenatal and post-hatched broiler chicks. A total of 140 broiler (Cobb500) eggs were randomly divided into two groups (n = 70 each), and on day 12 of incubation, eggs in one group received in ovo injection of 0...
2017: PloS One
https://www.readbyqxmd.com/read/28859292/exosomes-secreted-by-cardiomyocytes-subjected-to-ischaemia-promote-cardiac-angiogenesis
#20
Teresa M Ribeiro-Rodrigues, Tiago L Laundos, Rita Pereira-Carvalho, Daniela Batista-Almeida, Ricardo Pereira, Vanessa Coelho-Santos, Ana P Silva, Rosa Fernandes, Monica Zuzarte, Francisco J Enguita, Marina C Costa, Perpetua Pinto-do-Ó, Marta T Pinto, Pedro Gouveia, Lino Ferreira, Justin C Mason, Paulo Pereira, Brenda R Kwak, Diana S Nascimento, Henrique Girão
Aims: Myocardial infarction (MI) is the leading cause of morbidity and mortality worldwide and results from an obstruction in the blood supply to a region of the heart. In an attempt to replenish oxygen and nutrients to the deprived area, affected cells release signals to promote the development of new vessels and confer protection against MI. However, the mechanisms underlying the growth of new vessels in an ischaemic scenario remain poorly understood. Here, we show that cardiomyocytes subjected to ischaemia release exosomes that elicit an angiogenic response of endothelial cells (ECs)...
September 1, 2017: Cardiovascular Research
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