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https://www.readbyqxmd.com/read/28728764/experiences-of-daily-life-among-adolescents-with-asthma-a-struggle-with-ambivalence
#1
Marina Jonsson, Marja Schuster, Jennifer L P Protudjer, Anna Bergström, Ann-Charlotte Egmar, Inger Kull
OBJECTIVE: There is limited knowledge about how adolescents with asthma view their disease in daily life and how these views impact on management. The aim of this study was to describe experiences of daily life, with particular focus on thoughts, feelings and management of adolescents with asthma. METHODS: In this qualitative study, data were obtained from 10 interviews with adolescents (aged 16-18 years) with asthma recruited from the Swedish population-based prospective birth cohort, BAMSE...
July 2017: Journal of Pediatric Nursing
https://www.readbyqxmd.com/read/28728594/implementing-the-efftox-dose-finding-design-in-the-matchpoint-trial
#2
Kristian Brock, Lucinda Billingham, Mhairi Copland, Shamyla Siddique, Mirjana Sirovica, Christina Yap
BACKGROUND: The Matchpoint trial aims to identify the optimal dose of ponatinib to give with conventional chemotherapy consisting of fludarabine, cytarabine and idarubicin to chronic myeloid leukaemia patients in blastic transformation phase. The dose should be both tolerable and efficacious. This paper describes our experience implementing EffTox in the Matchpoint trial. METHODS: EffTox is a Bayesian adaptive dose-finding trial design that jointly scrutinises binary efficacy and toxicity outcomes...
July 20, 2017: BMC Medical Research Methodology
https://www.readbyqxmd.com/read/28726178/being-of-two-minds-assessing-vacillating-and-simultaneous-ambivalence-with-the-density-matrix
#3
James Camparo, Lorinda B Camparo
Ambivalence is a common experience that permeates a broad range of research. Unfortunately, quantifying ambivalence has proven a daunting task, with researchers limited to studying vacillating ambivalence, VA (i.e., temporal oscillations between favor/disfavor evaluations of an attitude object). Here, we demonstrate the use of the density matrix to measure both VA and what we term "simultaneous ambivalence" (SA): ambivalence that manifests itself as "in the moment" concurrent favor/disfavor evaluations. In a methodological study we gave participants the option of either single-responding or double-responding to questionnaire items regarding a controversial topic (i...
July 19, 2017: Behavior Research Methods
https://www.readbyqxmd.com/read/28723957/brain-synchronization-during-perception-of-facial-emotional-expressions-with-natural-and-unnatural-dynamics
#4
Dionysios Perdikis, Jakob Volhard, Viktor Müller, Kathrin Kaulard, Timothy R Brick, Christian Wallraven, Ulman Lindenberger
Research on the perception of facial emotional expressions (FEEs) often uses static images that do not capture the dynamic character of social coordination in natural settings. Recent behavioral and neuroimaging studies suggest that dynamic FEEs (videos or morphs) enhance emotion perception. To identify mechanisms associated with the perception of FEEs with natural dynamics, the present EEG (Electroencephalography)study compared (i) ecologically valid stimuli of angry and happy FEEs with natural dynamics to (ii) FEEs with unnatural dynamics, and to (iii) static FEEs...
2017: PloS One
https://www.readbyqxmd.com/read/28719918/-the-wish-for-a-child-in-the-case-of-permanent-infertility-development-of-the-german-questionnaire-on-attitudes-toward-motherhood
#5
Maike Fliegner, Hertha Richter-Appelt, Kerstin Krupp, Franziska Brunner
Study 1 Development of the questionnaire Most questionnaires on attitudes toward motherhood presume that the subject is fertile and positive and negative attitudes are represented on a one-dimensional scale. Moreover, the questionnaires often do not provide German versions and German norms. The aim of this study is to examine whether the German Questionnaire on Attitudes toward Motherhood ("FEMu") can be used to describe attitudes toward motherhood multi-dimensionally and whether it is applicable independent of a person's fertility status...
July 18, 2017: Psychotherapie, Psychosomatik, Medizinische Psychologie
https://www.readbyqxmd.com/read/28718864/-cognitive-behavioral-group-therapy-addressing-fear-of-progression-in-cancer-out-patients
#6
Bärbel Rudolph, Alexander Wünsch, Peter Herschbach, Andreas Dinkel
Fear of progression (FoP) is an appropriate, rational response to the real threat of cancer and its treatments. However, patients experiencing elevated, dysfunctional levels of FoP often feel severely distressed and are in need of treatment. We previously conducted a (partly-)randomized controlled study with cancer patients undergoing in-patient rehabilitation and showed that a brief, four-session cognitive-behavioral group therapy significantly reduced dysfunctional FoP. In this report, we describe the adaption of the cognitive-behavioral group therapy program for use with cancer out-patients...
June 29, 2017: Psychotherapie, Psychosomatik, Medizinische Psychologie
https://www.readbyqxmd.com/read/28708453/virulence-and-antibiotic-resistance-of-enterococci-isolated-from-healthy-breastfed-infants
#7
José M Landete, Ángela Peirotén, Margarita Medina, Juan L Arqués, Eva Rodríguez-Mínguez
Pathogenic ability has been extensively studied in clinical enterococci, but to a lesser extent in community-derived ones. Most studies to date in enterococci from healthy infants have been focused on Enterococcus faecalis, despite the growing concern about nosocomial infections caused by E. faecium. In this work, we studied the antibiotic resistance and virulence determinants of 26 E. faecalis and 15 E. faecium intestinal isolates from Spanish healthy breastfed infants. Overall, commensal enterococci studied contained antibiotic resistance and virulence genes, although their patterns were not according to those described for antibiotic-resistant hospital-associated enterococci...
July 14, 2017: Microbial Drug Resistance: MDR: Mechanisms, Epidemiology, and Disease
https://www.readbyqxmd.com/read/28705562/la-%C3%A2-double-transition%C3%A2-des-jeunes-atteints-de-cancer
#8
Thibaud Pombet
THE "DOUBLE TRANSITION" OF YOUNG PEOPLE AFFECTED BY CANCER.: Transition can refer to the transfer of a patient from a paediatric institution to an adult department, but it can also refer to the constitutive process of moving into adulthood. Based on a sociological field survey carried out on devices dedicated to adolescents and young adults affected by cancer in France, the impact of this ambivalence on care practices can be assessed. The current paradoxes the medical and care relationship is exposed to are thus identified...
July 2017: Soins. Pédiatrie, Puériculture
https://www.readbyqxmd.com/read/28698859/inflammasome-as-a-therapeutic-target-for-cancer-prevention-and-treatment
#9
REVIEW
Huyen Trang Ha Thi, Suntaek Hong
Chronic inflammation is a critical modulator of carcinogenesis through secretion of inflammatory cytokines, which leads to the formation of an inflammatory microenvironment. In this process, the inflammasome plays an important role in the expression and activation of interleukin (IL)-1β and IL-18 to promote cancer development. The inflammasome is a multiprotein complex consisting of several nucleotide-binding domain and leucine-rich repeat containing receptor, adaptor proteins, and caspase 1 (CASP1). It senses the various intracellular (damage-associated molecular patterns) and extracellular (pathogen-associated molecular patterns) stimuli...
June 2017: Journal of Cancer Prevention
https://www.readbyqxmd.com/read/28697791/blood-transfusion-in-elderly-patients-with-chronic-anemia-a-qualitative-analysis-of-the-general-practitioners-attitudes
#10
Sylvain Le Calvé, Dominique Somme, Joaquim Prud'homm, Aline Corvol
BACKGROUND: Blood transfusion in chronic anemia is not covered by guidelines specific to older adults. When they consider that this treatment is necessary in elderly patients, French general practitioners (GPs) contact a hospital specialist to plan a transfusion. METHODS: Twenty French GPs were questioned individually regarding their approach to blood transfusion using semi-structured interviews. Each interview was recorded, typed up verbatim and then coded using an inductive procedure by theme, in a cross-over design (two researchers) in two phases: analysis and summary, followed by grouping of the recorded comments...
July 11, 2017: BMC Family Practice
https://www.readbyqxmd.com/read/28694680/developing-a-tailored-texting-preventive-intervention-a-card-sort-methodology
#11
Jordan M Braciszewski, Tanya B Tran, Roland S Moore, Beth C Bock, Golfo K Tzilos, Patricia Chamberlain, Robert L Stout
PURPOSE: Intervention content written by adults for youth can result in miscommunication due to generational and cultural differences. Inviting at-risk youth to participate in the creation of intervention material can augment acceptability for their peers. METHODS: To improve intervention messaging, the present study examines the utility of a card sort technique when creating cellular phone text messages to be used in a preventive substance use intervention. During focus groups with 24 youth who are exiting the foster care system - a population with distinct cultural attributes - participants were asked to rate stage of change-specific health messages rooted in Motivational Interviewing and the Transtheoretical Model...
June 2017: Journal of Applied Biobehavioral Research
https://www.readbyqxmd.com/read/28693897/connexins-important-players-in-the-dissemination-of-prostate-cancer-cells
#12
REVIEW
Jonathan Boucher, Arnaud Monvoisin, Justine Vix, Marc Mesnil, Dominique Thuringer, Françoise Debiais, Laurent Cronier
Over the past 50 years, increasing experimental evidences have established that connexins (Cxs) and gap junctional intercellular communication (GJIC) ensure an important role in both the onset and development of cancerous processes. In the present review, we focus on the impact of Cxs and GJIC during the development of prostate cancer (PCa), from the primary growth mainly localized in acinar glands and ducts to the distant metastasis mainly concentrated in bone. As observed in several other types of solid tumours, Cxs and especially Cx43 exhibit an ambivalent role with a tumour suppressor effect in the early stages and, conversely, a rather pro-tumoral profile for most of invasion and dissemination steps to secondary sites...
July 7, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28693400/formulating-autism-systemically-part-2-a-12-year-prospective-case-study
#13
Nicky Brewerton, Katrina Robson, Patricia M Crittenden
This prospective case study illustrates the ideas on the developmental origins of some cases of autism that were described in Part 1 of this article. We explored and found support for several systemic hypotheses regarding the experience of 'Graeme' and his mother. Graeme's story is told prospectively from the age of 3 until 15. Three independent sources of information are reported: hypotheses from the literature and case review in Part 1 of this article, the school's experience, and observations from the assessments of attachment when Graeme was turning 6...
July 2017: Clinical Child Psychology and Psychiatry
https://www.readbyqxmd.com/read/28689764/wula-voices-of-aboriginal-women-on-barriers-to-accepting-smoking-cessation-support-during-pregnancy-findings-from-a-qualitative-study
#14
M Bovill, M Gruppetta, Y Cadet-James, M Clarke, B Bonevski, G S Gould
AIM: To gather Aboriginal women's stories of smoking and becoming pregnant to identify the barriers in accepting smoking cessation support during pregnancy. METHODS: Qualitative data were collected through use of yarning methodology between August 2015 and January 2016 by an Aboriginal Researcher with experience in social and community services. A short on-line survey was used to collect quantitative data. Interviews only recorded the therapeutic yarning process, which ranged from 9 to 45min duration, averaging 30min...
July 6, 2017: Women and Birth: Journal of the Australian College of Midwives
https://www.readbyqxmd.com/read/28683238/endocrine-trainees-exhibit-sensitive-but-conservative-attitudes-towards-the-management-of-endocrine-conditions-in-hiv-patients-in-singapore
#15
Seow Cherng Jye, Chen Abel Weiliang, Hoi Wai Han, Rinkoo Dalan
Objective With advances in the treatment of HIV infections, the life expectancy of people living with HIV (PWH) is fast approaching that of the general population. Endocrine and metabolic disorders occur more frequently in PWH than in the general population. This study assesses the knowledge, practice patterns and confidence levels among endocrinology trainees in Singapore in managing endocrine disorders in PWH. Methods An anonymous 31-item survey was administered to 23 endocrinology trainees. Four domains were assessed: (1) Previous exposure to endocrine disorders in PWH; (2) Attitudes towards treating PWH; (3) Case studies in endocrinology designed to assess for differences in treatment philosophy between a PWH and a non-infected counterpart; and (4) Confidence in managing endocrine disorders in PWH...
July 6, 2017: Endocrine Practice
https://www.readbyqxmd.com/read/28675714/processes-of-recovery-through-routine-or-specialist-treatment-for-borderline-personality-disorder-bpd-a-qualitative-study
#16
Christina Katsakou, Nancy Pistrang, Kirsten Barnicot, Hayley White, Stefan Priebe
BACKGROUND: Recovery processes in borderline personality disorder (BPD) are poorly understood. AIMS: This study explored how recovery in BPD occurs through routine or specialist treatment, as perceived by service users (SUs) and therapists. METHODS: SUs were recruited from two specialist BPD services, three community mental health teams, and one psychological therapies service. Semi-structured interviews were conducted with 48 SUs and 15 therapists...
July 4, 2017: Journal of Mental Health
https://www.readbyqxmd.com/read/28673262/increasing-the-treatment-motivation-of-patients-with-somatic-symptom-disorder-applying-the-urica-s-scale
#17
Johannes Mander, Georg Schaller, Hinrich Bents, Ulrike Dinger, Stephan Zipfel, Florian Junne
BACKGROUND: Therapeutic intervention programs for somatic symptom disorder (SSD) show only small-to-moderate effect sizes. These effects are partly explained by the motivational problems of SSD patients. Hence, fostering treatment motivation could increase treatment success. One central aspect in SSD patients might be damage to motivation because of symptomatic relapses. Consequently, the aim of the present study was to investigate associations between motivational relapse struggle and therapeutic outcome in SSD patients...
July 3, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28669369/young-people-s-perspectives-on-open-communication-between-family-members-when-a-parent-is-dying
#18
Nicola Turner
OBJECTIVE: Living with a parent who is approaching the end of life is profoundly troubling for young people. Research indicates that family communication about life-limiting parental illness can influence how young people manage living with dying. In particular, open communication between family members has been shown to be helpful. This paper reports on a study of young people's experiences of family interaction when a parent is dying and considers the practice of open communication in the context of young people's involvement in giving and receiving family care...
July 3, 2017: Palliative & Supportive Care
https://www.readbyqxmd.com/read/28666203/understanding-experiences-of-and-rationales-for-sharing-crack-smoking-equipment-a-qualitative-study-with-persons-who-smoke-crack-in-montr%C3%A3-al
#19
Hélène Poliquin, Karine Bertrand, Jorge Flores-Aranda, Élise Roy
BACKGROUND: The distribution of safer crack-smoking equipment has been implemented in several Canadian cities to reduce potential health risks such as transmission of blood borne viruses (BBV). Little is known about the perspectives of persons who smoke crack (PWSC) on sharing crack-smoking materials or using in settings where safer crack-smoking equipment is provided. This paper presents data from the perspective of PWSC in Montréal on their experiences of, and rationales for, sharing crack-smoking equipment, in light of the risks of BBV transmission...
June 27, 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/28663177/introduction-the-many-roads-toward-achieving-health-equity
#20
Alan B Cohen, Colleen M Grogan, Jedediah N Horwitt
This special issue of the Journal is devoted to understanding the many roads that lead toward achieving health equity. The eleven articles in the issue portray an America that is struggling with the clash between its historical ideal of pursuing equality for all and its ambivalence toward achieving equity in all social domains, especially health. Organized in five sections, the issue contains articles that examine and analyze: the role of civil rights law and the courts in shaping health equity; the political discourse that has framed our understanding of health equity; health policies that affect health equity, such as the Medicaid program, as well as related strategies that might help to improve equity, such as the use of mobile technologies to empower individuals; immigration policies and practices that impact health equity in marginalized populations; and commentaries in the final section that explore how the Affordable Care Act has addressed health equity, how repeal of the law would jeopardize equity gains, and how the political discourse and culture of the Trump administration could adversely affect health equity...
June 29, 2017: Journal of Health Politics, Policy and Law
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