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https://www.readbyqxmd.com/read/28092450/preintervention-profiles-of-information-motivational-and-behavioral-self-efficacy-for-methamphetamine-use-and-hiv-medication-adherence-among-gay-and-bisexual-men
#1
Tyrel J Starks, Brett M Millar, Jonathan M Lassiter, Jeffrey T Parsons
Although rates of crystal methamphetamine use in the United States have fallen from their peak in the mid-2000s, use remains a major public health concern, which disproportionately affects gay and bisexual men (GBM). It poses a particular challenge for HIV-positive men, for whom it has been linked to medication adherence problems as well as compromised immune function. Although the information, motivation, and behavioral skills (IMB) model has been widely used to conceptualize health behavior, little is known about GBM's initial levels of information, motivation, and behavioral self-efficacy to improve HIV medication adherence and to reduce crystal methamphetamine use at the outset of treatment...
January 16, 2017: AIDS Patient Care and STDs
https://www.readbyqxmd.com/read/28092147/should-serum-calcitonin-be-routinely-measured-in-patients-presenting-with-thyroid-nodule
#2
William P Tormey, Brendan Byrne, Arnold D Hill, Mark Sherlock, Christopher J Thompson
BACKGROUND: The European Thyroid Association recommends serum calcitonin measurement in thyroid nodule cases. In contrast, the American Thyroid Association is ambivalent. In this institution, thyroid nodules cases are subject to a multidisciplinary evaluation of the clinical history and examination, ultrasound and scintigraphy, CT scan and sometimes MRI scan, biochemistry and histopathology of biopsies. We report on the current use of plasma calcitonin measurements in the context of changing practice which has not included screening of all thyroid nodules...
January 13, 2017: Minerva Endocrinologica
https://www.readbyqxmd.com/read/28089924/water-juice-or-soda-mothers-and-grandmothers-of-preschoolers-discuss-the-acceptability-and-accessibility-of-beverages
#3
Karin Eli, Agneta Hörnell, Mahnoush Etminan Malek, Paulina Nowicka
Intake of sugary beverages is strongly associated with weight gain and obesity among children; however, differences between mothers' and grandmothers' attitudes and practices concerning young children's beverage consumption remain unclear. This is notable since about a quarter of families in the US and the UK rely on grandparents as the main providers of informal childcare. The aim of this study is to examine mothers' and maternal grandmothers' attitudes, knowledge, and practices regarding preschool-age children's beverage consumption...
January 12, 2017: Appetite
https://www.readbyqxmd.com/read/28088785/the-igh-locus-3-cis-regulatory-super-enhancer-co-opts-aid-for-allelic-transvection
#4
Sandrine Le Noir, Brice Laffleur, Claire Carrion, Armand Garot, Sandrine Lecardeur, Eric Pinaud, Yves Denizot, Jane Skok, Michel Cogné
Immunoglobulin heavy chain (IgH) alleles have ambivalent relationships: they feature both allelic exclusion, ensuring monoallelic expression of a single immunoglobulin (Ig) allele, and frequent inter-allelic class-switch recombination (CSR) reassembling genes from both alleles. The IgH locus 3' regulatory region (3'RR) includes several transcriptional cis-enhancers promoting activation-induced cytidine deaminase (AID)-dependent somatic hypermutation (SHM) and CSR, and altogether behaves as a strong super-enhancer...
January 10, 2017: Oncotarget
https://www.readbyqxmd.com/read/28088074/anti-angiogenic-treatment-in-breast-cancer-facts-successes-failures-and-future-perspectives
#5
REVIEW
Kim C Aalders, Konstantinos Tryfonidis, Elżbieta Senkus, Fatima Cardoso
Angiogenesis is one of the hallmarks of cancer and a crucial requisite in the development of tumors. Interrupting this process by blocking the vascular endothelial growth factor (VEGF) with the monoclonal antibody bevacizumab has been considered a possible breakthrough in the treatment of various types of cancer, especially for advanced disease. However in breast cancer, studies have shown ambivalent results causing debate about the value of this drug. In this article, we review the evidence for anti-angiogenic treatment options for breast cancer, as well as discuss the possible factors limiting the effectiveness of anti-angiogenic agents and offer a recommendation regarding the future research on these therapies for the treatment of breast cancer...
January 3, 2017: Cancer Treatment Reviews
https://www.readbyqxmd.com/read/28077156/interventions-following-a-high-violence-risk-assessment-score-a-naturalistic-study-on-a-finnish-psychiatric-admission-ward
#6
Jenni Kaunomäki, Markus Jokela, Raija Kontio, Tero Laiho, Eila Sailas, Nina Lindberg
BACKGROUND: Patient aggression and violence against staff members and other patients are common concerns in psychiatric units. Many structured clinical risk assessment tools have recently been developed. Despite their superiority to unaided clinical judgments, staff has shown ambivalent views towards them. A constant worry of staff is that the results of risk assessments would not be used. The aims of the present study were to investigate what were the interventions applied by the staff of a psychiatric admission ward after a high risk patient had been identified, how frequently these interventions were used and how effective they were...
January 11, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28069955/ambivalent-stereotypes-link-to-peace-conflict-and-inequality-across-38-nations
#7
Federica Durante, Susan T Fiske, Michele J Gelfand, Franca Crippa, Chiara Suttora, Amelia Stillwell, Frank Asbrock, Zeynep Aycan, Hege H Bye, Rickard Carlsson, Fredrik Björklund, Munqith Dagher, Armando Geller, Christian Albrekt Larsen, Abdel-Hamid Abdel Latif, Tuuli Anna Mähönen, Inga Jasinskaja-Lahti, Ali Teymoori
A cross-national study, 49 samples in 38 nations (n = 4,344), investigates whether national peace and conflict reflect ambivalent warmth and competence stereotypes: High-conflict societies (Pakistan) may need clearcut, unambivalent group images distinguishing friends from foes. Highly peaceful countries (Denmark) also may need less ambivalence because most groups occupy the shared national identity, with only a few outcasts. Finally, nations with intermediate conflict (United States) may need ambivalence to justify more complex intergroup-system stability...
January 9, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28068319/fbxo32-suppresses-breast-cancer-tumorigenesis-through-targeting-klf4-to-proteasomal-degradation
#8
H Zhou, Y Liu, R Zhu, F Ding, Y Wan, Y Li, Z Liu
Krüppel-like factor 4 (KLF4, GKLF) is a zinc-finger transcription factor involved in a large variety of cellular processes, including apoptosis, cell cycle progression, as well as stem cell renewal. KLF4 is critical for cell fate decision and has an ambivalent role in tumorigenesis. Emerging data keep reminding us that KLF4 dysregulation either facilitates or impedes tumor progression, making it important to clarify the regulating network of KLF4. Like most transcription factors, KLF4 has a rather short half-life within the cell and its turnover must be carefully orchestrated by ubiquitination and ubiquitin-proteasome system...
January 9, 2017: Oncogene
https://www.readbyqxmd.com/read/28068109/not-a-mom-thing-predictors-of-gatekeeping-in-same-sex-and-heterosexual-parent-families
#9
Kristin K Sweeney, Abbie E Goldberg, Randi L Garcia
The current study is the first to examine parental gatekeeping in both same-sex (57 female, 51 male) and heterosexual (n = 82) couples, all of whom became parents via adoption. Aspects of the individual, the couple, and the work context, measured preadoption, were examined as predictors of gatekeeping. Gatekeeping refers to attitudes and behaviors aimed at regulating and limiting the involvement of the other parent in housework and child care and was measured 2 years postadoption. Findings revealed that women in heterosexual relationships reported higher gatekeeping compared with all other groups, and men in same-sex relationships reported higher gatekeeping compared with women in same-sex relationships and men in heterosexual relationships...
January 9, 2017: Journal of Family Psychology: JFP
https://www.readbyqxmd.com/read/28060031/attitudes-of-nursing-students-about-pressure-injury-prevention
#10
Layla J Garrigues, Juliana C Cartwright, Donna Z Bliss
PURPOSE: The objective of this study was to examine the attitudes of baccalaureate nursing students toward their role in pressure injury prevention (PIP) and describe how clinical experiences influence their attitudes. Understanding students' attitudes and experiences related to PIP may facilitate development of evidence-based interventions for PIP by nurses. DESIGN: Qualitative exploratory descriptive design. SETTING AND SUBJECTS: Participants were 16 senior nursing students enrolled in a prelicensure baccalaureate nursing program in an accredited school of nursing...
January 3, 2017: Journal of Wound, Ostomy, and Continence Nursing
https://www.readbyqxmd.com/read/28058729/role-of-the-attachment-style-in-determining-the-association-between-headache-features-and-psychological-symptoms-in-migraine-children-and-adolescents-an-analytical-observational-case-control-study
#11
Samuela Tarantino, Cristiana De Ranieri, Cecilia Dionisi, Valentina Gagliardi, Maria Francesca Paniccia, Alessandro Capuano, Roberto Frusciante, Martina Balestri, Federico Vigevano, Simonetta Gentile, Massimiliano Valeriani
OBJECTIVE: We aimed to study the role of attachment style on headache severity and psychological symptoms in migraineurs children/adolescents. Moreover, we investigated the association between attachment style, migraine severity, and psychological symptoms. BACKGROUND: Attachment theory suggests that early interpersonal relationships may be important determinants of psychopathology and pain management. In particular, individuals with insecure attachment styles have been shown to experience more pain than people with secure attachment style...
January 6, 2017: Headache
https://www.readbyqxmd.com/read/28057447/antidepressant-prescribing-by-pediatricians-a-mixed-methods-analysis
#12
Anne K Tulisiak, Jillian A Klein, Emily Harris, Marissa J Luft, Heidi K Schroeder, Sarah A Mossman, Sara T Varney, Brooks R Keeshin, Sian Cotton, Jeffrey R Strawn
Among pediatricians, perceived knowledge of efficacy, tolerability, dosing, and side effects of antidepressants represent significant sources of variability in the use of these medications in youth with depressive and anxiety disorders. Importantly, the qualitative factors that relate to varying levels of comfort with antidepressants and willingness to prescribe are poorly understood. Using a mixed-methods approach, in-depth interviews were conducted with community-based and academic medical center-based pediatricians (N = 14)...
January 2, 2017: Current Problems in Pediatric and Adolescent Health Care
https://www.readbyqxmd.com/read/28056582/attitudes-of-health-professionals-towards-the-stigma-surrounding-depression-in-times-of-economic-crisis
#13
Maria Saridi, Aikaterini Kordosi, Aikaterini Toska, Lily Evangelia Peppou, Marina Economou, Kyriakos Souliotis
INTRODUCTION: The stigma of mental illness and the ensuing social exclusion are due to the lack of knowledge on the causality of mental illness. AIM: The purpose of this study was to record the stigmatic attitudes of health professionals towards depression, patients suffering from it and the available therapeutic approaches. MATERIAL AND METHODS: The sample of the study included 609 health professionals working in the General Hospital of Corinth...
January 1, 2017: International Journal of Social Psychiatry
https://www.readbyqxmd.com/read/28043173/glucocorticoid-targeted-therapies-for-the-treatment-of-rheumatoid-arthritis
#14
Cindy Strehl, Marlies C van der Goes, Johannes W J Bijlsma, Johannes W G Jacobs, Frank Buttgereit
The beneficial effects of glucocorticoids are highly regarded in the treatment of inflammatory diseases. In rheumatoid arthritis, these drugs are widely used because they effectively reduce signs and symptoms of the disease, and exert disease-modifying effects. However, both patients and physicians frequently associate glucocorticoids with a variety of adverse effects which hamper adherence. Due to this ambivalent nature of these drugs, several new glucocorticoids or glucocorticoid receptor ligands are being developed, aiming at improving their benefit-risk balance...
January 3, 2017: Expert Opinion on Investigational Drugs
https://www.readbyqxmd.com/read/28008576/-barriers-to-addressing-pregnant-patients-cigarette-and-alcohol-use-a-focus-group-study-with-gynecologists
#15
A Stiegler, L Bieber, K Karacay, F Wernz, A Batra
Objectives/Purpose: Alcohol drinking and tobacco smoking pose high health risks for the unborn child. Even though routine testing during the course of pregnancy facilitates early intervention, addressing substance use in pregnancy seems to be more difficult. The aim of the study was to identify barriers to addressing pregnant patients' cigarette and alcohol use. Methods: 2 focus groups (in total N=10 participants) were conducted with gynaecologists. The transcripts of the discussions were analysed using Mayring's approach of qualitative text analysis...
December 2016: Das Gesundheitswesen
https://www.readbyqxmd.com/read/28003100/how-social-is-recreational-running-findings-from-a-qualitative-study-in-london-and-implications-for-public-health-promotion
#16
Russell Hitchings, Alan Latham
Recreational running is increasingly widespread and could therefore be seen as the obvious target for those hoping to encourage greater public health through exercise. Existing qualitative research on this topic has, however, tended to focus on groups of highly committed runners. It is accordingly unclear whether their findings can be extrapolated to the much larger population of comparatively casual runners. This existing work has also tended to emphasise the social nature of the activity in particular ways...
December 18, 2016: Health & Place
https://www.readbyqxmd.com/read/28002770/neutrality-in-medicine-and-health-professionals-from-ethnic-minority-groups-the-case-of-arab-health-professionals-in-israel
#17
Yael Keshet, Ariela Popper-Giveon
The ethos of neutrality dominates biomedicine. It has, however, been criticized for leading to a disregard for diversity in medicine. In this article we employ the 'inclusion and difference' approach to gain an understanding of why the ethos of neutrality, on the one hand, and tensions associated with race/ethnicity, on the other, are relevant to the work of ethnic minority health professionals. We sought to explore tensions associated with neutrality in medicine from the point of view of ethnic minority professionals who work in a context of political conflict...
December 13, 2016: Social Science & Medicine
https://www.readbyqxmd.com/read/28000920/on-fascination-and-fear-of-annihilation
#18
Michel Thys
In this paper fascination phenomenologically is described as a state of radically being captured by an imposing object. What is left of the impoverished and paralysed subject clings to the exclusive fascinating object. Fascination is the eye of the storm of extreme ambivalence towards an exclusive object: being the only remaining object it is necessary for living in an object world, but at the same time it is threatening to life by absorbing the subject totally. So the subject is sucked in by a yet frightening object...
December 21, 2016: International Journal of Psycho-analysis
https://www.readbyqxmd.com/read/27999555/intergenerational-transmission-of-reflective-functioning
#19
Anna M Rosso, Cinzia Airaldi
The present study investigated whether, and to what extent, reflective functioning (RF) during preadolescence is associated with maternal attachment security and RF, and with the child's attachment security. Thirty-nine mother-preadolescent child dyads from a non-clinical population participated in the study. Maternal and child RF were assessed by applying the Reflective Functioning Scale to the Adult Attachment Interview (AAI) and to the Child Attachment Interview transcripts. Children of mothers who showed a secure attachment model regarding the relationship with their parents during childhood reported higher levels of RF than the children of mothers who were classified as insecure on the AAI...
2016: Frontiers in Psychology
https://www.readbyqxmd.com/read/27992049/the-treatment-of-madness-in-the-nineteenth-and-twentieth-centuries-discourses-about-curability-in-spanish-mental-health-care-1890-1917
#20
José Javier Plumed Domingo, Luis Miguel Rojo Moreno
This article studies the discourses about curability constructed by Spanish mental health practitioners in the transition from the nineteenth to the twentieth century. While in the 1870s and 1880s the predominant discourse promoted by doctors attached to private institutions was extremely optimistic, it subsequently changed and became more pessimistic regarding treatment outcomes. However, given phrenopathists' professional needs, they continued to profess more or less unshakeable confidence in the therapeutic abilities of psychiatry...
October 2016: História, Ciências, Saúde—Manguinhos
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