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Alessandra Carè, Maria Bellenghi, Paola Matarrese, Lucia Gabriele, Stefano Salvioli, Walter Malorni
A sexual dimorphism at the cellular level has been suggested to play a role in cancer onset and progression. In particular, very recent studies have unraveled striking differences between cells carrying XX or XY chromosomes in terms of response to stressful stimuli, indicating the presence of genetic and epigenetic differences determining sex-specific metabolic or phenotypic traits. Although this field of investigation is still in its infancy, available data suggest a key role of sexual chromosomes in determining cell life or death...
January 19, 2018: Cell Death and Differentiation
Vera Limpens, Tim Buszard, Emma Shoemaker, Geert J P Savelsbergh, Machar Reid
PURPOSE: The net height in tennis (0.91 m) is approximately 50% of a professional tennis player's height. Children are also expected to play with this net height, even though it is approximately 70% of the average 10-year-old's height. This study examined the immediate effect of lowering net height on the performance characteristics of skilled junior tennis players aged 10 years and younger. METHOD: Sixteen players were matched in 8 pairs of even tennis ability and same sex...
January 19, 2018: Research Quarterly for Exercise and Sport
Xiaomin Kang, Baoqi Huang, Guodong Qi
Recently, with the development of artificial intelligence technologies and the popularity of mobile devices, walking detection and step counting have gained much attention since they play an important role in the fields of equipment positioning, saving energy, behavior recognition, etc. In this paper, a novel algorithm is proposed to simultaneously detect walking motion and count steps through unconstrained smartphones in the sense that the smartphone placement is not only arbitrary but also alterable. On account of the periodicity of the walking motion and sensitivity of gyroscopes, the proposed algorithm extracts the frequency domain features from three-dimensional (3D) angular velocities of a smartphone through FFT (fast Fourier transform) and identifies whether its holder is walking or not irrespective of its placement...
January 19, 2018: Sensors
Prativa Dhakal, Mangala Shrestha, Dharanidhar Baral, Santosh Pathak
Background: In Nepal, the maternal mortality ratio is 281 per thousand live births, among which 40% mortality occurs during home delivery. Home delivery increases the risk of maternal and neonatal mortality and morbidity due to the birth not assisted by skilled attendant. This study was carried out to determine the factors affecting the place of delivery among the mothers residing in Jhorahat VDC, Morang district, Nepal. Methods: A mixed method study using interviews based on semi-structured questionnaire (n=93) among mothers and two focus group discussion among decision makers of the house and female community health volunteers was conducted between November to December 2012...
January 2018: International Journal of Community Based Nursing and Midwifery
Peter Brinkrolf, Roman Lukas, Ulf Harding, Sebastian Thies, Joachim Gerss, Hugo Van Aken, Hans Lemke, Udo Schniedermeier, Andreas Bohn
Objective: High-quality chest compressions during cardiopulmonary resuscitation (CPR) play a significant role in surviving cardiac arrest. Chest-compression quality can be measured and corrected by real-time CPR feedback devices, which are not yet commonly used. This article looks at the acceptance of such systems in comparison of equipped and unequipped personnel. Design: Two groups of emergency medical services' (EMS) personnel were interviewed using standardized questionnaires...
January 11, 2018: International Journal for Quality in Health Care
Win Mar
Nuclear Medicine was established in Myanmar in 1963 by Dr Soe Myint and International Atomic Energy expert Dr R. Hochel at Yangon General Hospital. Nuclear medicine diagnostic and therapeutic services started with Probe Scintillation Detector Systems and rectilinear scanner. In the early stage, many Nuclear Medicine specialists from the International Atomic Energy Agency (IAEA) spent some time in Myanmar and made significant contributions to the development of Nuclear Medicine in our country. The department participated in various IAEA technical cooperation projects and regional cooperation projects...
2018: Asia Oceania Journal of Nuclear Medicine & Biology
Li Liu, Shisuo Fan
The biochars were produced from wheat straw (WSBC) at different pyrolytic temperatures. Biochars were characterized by multiple instrumental techniques and were applied to remove Cd from aqueous solution. The removal mechanism was explored, and the quantitative information regarding the relative contribution of related mechanisms to Cd sorption on biochars was provided. The results showed that pseudo-second-order kinetic model, TC (two-compartment) model, and Freundlich isotherm could well fit the process of Cd sorption on biochars...
January 10, 2018: Environmental Science and Pollution Research International
Bikash Sahay, Kathleen Bashant, Nicole J Nelson, Rebeca L Patsey, Shiva Kumar Gadila, Rebecca Boohaker, Ashutosh Verma, Klemen Strle, Timothy J Sellati
Host genotype influences the severity of murine Lyme borreliosis, caused by the spirochetal bacterium Borrelia burgdorferi C57BL/6 (B6) mice develop mild, whereas C3H/HeN (C3H) mice develop severe Lyme arthritis. Differential expression of interleukin 10 (IL-10) has long been associated with mouse strain differences in Lyme pathogenesis; however, the underlying mechanism(s) of this genotype-specific IL-10 regulation remained elusive. Herein we reveal a cAMP-mediated mechanism of IL-10 regulation in B6 macrophages that is substantially diminished in C3H macrophages...
January 8, 2018: Infection and Immunity
Chetan Jinadatha, Frank C Villamaria, John D Coppin, Charles R Dale, Marjory D Williams, Ryan Whitworth, Mark Stibich
BACKGROUND: While research has demonstrated the importance of a clean health care environment, there is a lack of research on the role portable medical equipment (PME) play in the transmission cycle of healthcare-acquired infections (HAIs). This study investigated the patterns and sequence of contact events among health care workers, patients, surfaces, and medical equipment in a hospital environment. METHODS: Research staff observed patient care events over six different 24 h periods on six different hospital units...
December 28, 2017: BMC Infectious Diseases
A I Shahin, Yanhui Guo, K M Amin, Amr A Sharawi
Background: White blood cells (WBCs) play a crucial role in the diagnosis of many diseases according to their numbers or morphology. The recent digital pathology equipments investigate and analyze the blood smear images automatically. The previous automated segmentation algorithms worked on healthy and non-healthy WBCs separately. Also, such algorithms had employed certain color components which leak adaptively with different datasets. Methods: In this paper, a novel segmentation algorithm for WBCs in the blood smear images is proposed using multi-scale similarity measure based on the neutrosophic domain...
December 2018: Health Information Science and Systems
J Pierreville, C Serrano, H van den Brink, P Prognon, J Pineau, N Martelli
3D printing plays an increasingly important role in the medical sector and particularly in surgery. Nowadays, numerous manufacturers benefit from this technology to produce their medical devices and some hospitals have also purchased 3D printers. In this context, the aim of the present study was to study the distribution and the use of 3D printing in French hospitals in order to its main features in surgery. By conducting a national survey, we targeted hospitals equipped with 3D printers and those using external providers to benefit from this technology...
December 22, 2017: Annales Pharmaceutiques Françaises
Renée Lampe, Varvara Turova, Ana Alves-Pinto
PURPOSE: Patients with cerebral palsy with severe motor disabilities are limited not only in everyday life activities but also in choice of their hobbies. Playing a musical instrument is for the majority not possible, even though music constitutes a central component of many relaxation activities for people with disabilities. To give affected patients the opportunity to make music and to learn piano playing through somatosensory perception, a prototype of piano jacket was developed. METHOD: A cycling jacket was equipped with boxes, each representing a musical note, incorporated into the sleeves...
December 23, 2017: Disability and Rehabilitation. Assistive Technology
Michiel Wichers, Wilson Siguemasa Iramina, Sérgio Médici de Eston, Anna Luiza Marques Ayres da Silva
Mining plays an important role in Brazilian exports. On the other hand, large urban centers like São Paulo, with approximately 21 million inhabitants, also demand an increasing domestic consumption of natural resources, such as construction aggregate. There are many quarries located in the surroundings of urban centers in Brazil, competing with the growth of urbanized areas. Such proximity leads to a series of conflicts involving quarries and surrounding communities, where the increase in noise levels is highlighted...
December 22, 2017: Environmental Monitoring and Assessment
Mary D Klinnert, Genery Booster, Mandy Copeland, Jennifer Moyer Darr, Lisa J Meltzer, Michael Miller, Alyssa Oland, Shauna Perry, Brian K Wise, Bruce G Bender
OBJECTIVE: To describe the behavioral components and complications in treating pediatric patients with atopic dermatitis (AD) and the critical role of behavioral health professionals in addressing disease impact and behavioral aspects of disease management for these patients and families. DATA SOURCES: Studies and review articles were selected from medical and psychology databases for relevance to pertinent topics. RESULTS: AD has significant negative effects in affected individuals and their families on quality of life, behavioral, emotional, and sleep disturbances, and family functioning...
January 2018: Annals of Allergy, Asthma & Immunology
Alessandra Prioreschi, Soren Brage, Kylie D Hesketh, Jill Hnatiuk, Kate Westgate, Lisa K Micklesfield
BACKGROUND: Physical activity is considered to have health benefits across the lifespan but levels, patterns, and correlates have not been well described in infants and toddlers under the age of two years. METHODS: This study aimed to describe objectively and subjectively measured physical activity in a group of South African infants aged 3- to 24-months (n = 140), and to investigate individual and maternal correlates of physical activity in this sample. Infants' physical activity was measured using an Axivity AX3 wrist-worn accelerometer for one week and the mean vector magnitude was calculated...
December 22, 2017: International Journal of Behavioral Nutrition and Physical Activity
Larisa Ryskalin, Gloria Lazzeri, Marina Flaibani, Francesca Biagioni, Stefano Gambardella, Alessandro Frati, Francesco Fornai
The mammalian Target of Rapamycin (mTOR) is a molecular complex equipped with kinase activity which controls cell viability being key in the PI3K/PTEN/Akt pathway. mTOR acts by integrating a number of environmental stimuli to regulate cell growth, proliferation, autophagy, and protein synthesis. These effects are based on the modulation of different metabolic pathways. Upregulation of mTOR associates with various pathological conditions, such as obesity, neurodegeneration, and brain tumors. This is the case of high-grade gliomas with a high propensity to proliferation and tissue invasion...
2017: BioMed Research International
Kari Kindschi, Michael Higgins, Andrea Hillman, Gregory Penczek, Andrew Lincoln
Background/aim: Lacrosse is one of the fastest growing sports in the USA. Efforts to minimise head injuries focus on promoting safe play through player and coach education, rules enforcement and use of effective protective equipment. The study aims to determine event characteristics of high-magnitude head impacts in men's collegiate lacrosse competitions through video analysis. Methods: Seventeen Division I men's collegiate lacrosse players wore instrumented helmets that collected biomechanical measures of head impacts...
2017: BMJ Open Sport & Exercise Medicine
Helena Lauri
High-resolution computed tomography (HRCT) is a method of examination which is more precise than chest 2-rat in the diagnosis and monitoring of diseases of the lung tissue and the airways. Modern CT equipment enables a volume HRCT scan covering the whole lung tissue. HRCT slices can also be constructed from contrast-enhanced CT scans of the chest of the whole body. HRCT of the lungs can be applied to the diagnosis of both acute and more chronic diffuse diseases of the lung tissue and the airways. The best-known indications for HRCT include idiopathic interstitial pneumonias, such as idiopathic pulmonary fibrosis...
2017: Duodecim; Lääketieteellinen Aikakauskirja
C Loboda, J Vigneron, C Mulot, I May, B Demore
French preparation guidelines state that pharmacy staff who manipulate cytotoxic drugs have to follow specific training. In order to assess the pharmaceutical assistants' skills and knowledge, we developed a "Cytotoxic Preparation Centralized Unit (CPCU) of errors," derived from the Canadian concept of "Chamber of horrors." A table listing 20 mistakes to track down was created and each pharmaceutical assistant spent 20 min in the "CPCU of errors" with the pharmacist, who wrote down the spotted mistakes in real time...
January 1, 2017: Journal of Oncology Pharmacy Practice
Mohamed Rabie, Christian Michael Franck
Gases for electrical insulation are essential for the operation of electric power equipment. This review gives a brief history of gaseous insulation that involved the emergence of the most potent industrial greenhouse gas known today, namely sulfur hexafluoride. SF6 opened up the way to space-saving equipment for the transmission and distribution of electrical energy. Its ever-rising usage in the electrical grid also played a decisive role in the continuous increase of atmospheric SF6 abundance over the last decades...
December 13, 2017: Environmental Science & Technology
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