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https://www.readbyqxmd.com/read/29778825/nano-spray-drying-for-encapsulation-of-pharmaceuticals
#1
REVIEW
Cordin Arpagaus, Andreas Collenberg, David Rütti, Elham Assadpour, Seid Mahdi Jafari
Many pharmaceuticals such as pills, capsules, or tablets are prepared in a dried and powdered form. In this field, spray drying plays a critical role to convert liquid pharmaceutical formulations into powders. In addition, in many cases it is necessary to encapsulate bioactive drugs into wall materials to protect them against harsh process and environmental conditions, as well as to deliver the drug to the right place and at the correct time within the body. Thus, spray drying is a common process used for encapsulation of pharmaceuticals...
May 17, 2018: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/29758979/developmental-screening-tool-accuracy-and-feasibility-of-non-invasive-anaemia-estimation
#2
Raja Muthalagu, Vijayan Thulasi Bai, Doreen Gracias, Sheila John
Anaemia is predicted as one of the serious communal health issue in the world. The deficiency exists most common among children and women. A substantial issue prevails in providing quality healthcare services to rural communities, which remains a challenge to health service providers throughout the world. Traditionally physician and health workers recognized anaemia from certain clinical findings, such as pallor of the conjunctivae, nail beds, lips, tongue, and oral mucosa. Confirmation of anaemic condition through physical examination of Dorsum of a tongue or lower bulbar conjunctiva is a subjective analysis...
April 30, 2018: Technology and Health Care: Official Journal of the European Society for Engineering and Medicine
https://www.readbyqxmd.com/read/29754153/-implementation-of-effective-infection-control-furnishing-a-dental-practice
#3
A M G A Laheij, J J de Soet, C M C Volgenant
The increasing resistance to antibiotics and the aging of the population of patients who visit the dental practice can lead to more frequent infections with (resistant) microorganisms. The prevention of cross contamination by the implementation of effective measures in the area of hygiene and procedures of infection control is therefore important. The furnishing of a dental practice can play an important part in prevention. What are the important issues in furnishing a practice? A distinction is made between 'critical' and 'non-critical' rooms...
May 2018: Nederlands Tijdschrift Voor Tandheelkunde
https://www.readbyqxmd.com/read/29753229/novel-agnws-pan-tpu-membrane-for-point-of-use-drinking-water-electrochemical-disinfection
#4
Xiaojun Tan, Chao Chen, Yongyou Hu, Junjie Wen, Yanzhe Qin, Jianhua Cheng, Yuancai Chen
The safety of drinking water remains a major challenge in developing countries and point-of-use (POU) drinking water treatment device plays an important role in decentralised drinking water safety. In this study, a novel material, i.e. a silver nanowires-polyacrylonitrile/thermoplastic polyurethane (AgNWs-PAN/TPU) composite membrane, was fabricated via electrospinning and vacuum filtration deposition. Morphological and structural characterisation showed that the PAN/TPU fibres had uniform diameters and enhanced mechanical properties...
May 9, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29750600/exploring-respiratory-protection-practices-for-prominent-hazards-in-healthcare-settings
#5
Kerri Wizner, Mahiyar Nasarwanji, Edward Fisher, Andrea L Steege, James M Boiano
The use of respiratory protection, an important component of personal protective equipment (PPE) in healthcare, is dependent on the hazard and environmental conditions in the workplace. This requires the employer and healthcare worker (HCW) to be knowledgeable about potential exposures and their respective protective measures. However, the use of respirators is inconsistent in healthcare settings, potentially putting HCWs at risk for illness or injury. To better understand respirator use, barriers, and influences, the National Institute for Occupational Safety and Health (NIOSH) Health and Safety Practices Survey of Healthcare Workers provided an opportunity to examine self-reported use of respirators and surgical masks for targeted hazards...
May 11, 2018: Journal of Occupational and Environmental Hygiene
https://www.readbyqxmd.com/read/29743358/the-chromatin-remodeling-factor-spoc1-acts-as-a-cellular-restriction-factor-against-human-cytomegalovirus-by-repressing-the-major-immediate-early-promoter
#6
Anna Reichel, Anne-Charlotte Stilp, Myriam Scherer, Nina Reuter, Sören Lukassen, Bahram Kasmapour, Sabrina Schreiner, Luka Cicin-Sain, Andreas Winterpacht, Thomas Stamminger
The cellular protein SPOC1 (survival time-associated PHD finger protein in ovarian cancer 1) acts as a regulator of chromatin structure and DNA damage response. It binds H3K4me2/3 containing chromatin and promotes DNA condensation by recruiting corepressors such as KAP-1 and H3K9 methyltransferases. Previous studies identified SPOC1 as a restriction factor against human adenovirus (HAdV) infection that is antagonized by E1B-55K/E4orf6-dependent proteasomal degradation. Here, we demonstrate that, in contrast to HAdV-infected cells, SPOC1 is transiently upregulated during the early phase of HCMV replication...
May 9, 2018: Journal of Virology
https://www.readbyqxmd.com/read/29737187/family-systems-training-for-medical-students
#7
Hiran Thabrew
OBJECTIVES: To evaluate whether a workshop on family systems delivered to medical students could improve participants' understanding of families from a systemic point of view and help them recognise and address systemic issues that may be affecting their patients. METHOD: Fifth year (senior) medical students ( n = 36) from the University of Auckland participated in a 90-min workshop about family systems. Pre- and post-workshop, self-reported measures of knowledge and confidence were completed and qualitative feedback was also obtained from participants...
May 1, 2018: Australasian Psychiatry: Bulletin of Royal Australian and New Zealand College of Psychiatrists
https://www.readbyqxmd.com/read/29732653/the-regenerative-journey-of-pericytes-towards-clinical-translation
#8
REVIEW
William Cathery, Ashton Faulkner, Davide Maselli, Paolo Madeddu
Coronary artery disease (CAD) is the single leading cause of death worldwide. Advances in treatment and management have significantly improved patient outcomes. On the other hand, although mortality rates have decreased, more people are left with sequelae that require additional treatment and hospitalization. Moreover, patients with severe nonrevascularizable CAD remain with the only option of heart transplantation, which is limited by the shortage of suitable hearts. In recent years, cell-based regenerative therapy has emerged as a possible alternative treatment, with several regenerative medicinal products already in the clinical phase of development and other emerging as competitive preclinical solutions...
May 7, 2018: Stem Cells
https://www.readbyqxmd.com/read/29721450/multibody-modelling-of-ligamentous-and-bony-stabilizers-in-the-human-elbow
#9
REVIEW
Mara Terzini, Elisabetta Maria Zanetti, Alberto Luigi Audenino, Giovanni Putame, Laura Gastaldi, Stefano Pastorelli, Elisa Panero, Arman Sard, Cristina Bignardi
The elbow ligamentous and bony structures play essential roles in the joint stability. Nevertheless, the contribution of different structures to joint stability is not yet clear and a comprehensive experimental investigation into the ligament and osseous constraints changes in relation to joint motions would be uphill and somehow unattainable, due to the impossibility of obtaining all the possible configurations on the same specimen. Therefore, a predictive tool of the joint behavior after the loss of retentive structures would be helpful in designing reconstructive surgeries and in pre-operative planning...
October 2017: Muscles, Ligaments and Tendons Journal
https://www.readbyqxmd.com/read/29718082/integration-of-neuropsychological-services-in-a-va-hiv-primary-care-clinic
#10
Moira C Dux, Terry Lee-Wilk
The Department of Veteran Affairs (VA) is the largest health care provider for individuals with human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS), with >28,000 Veterans with HIV/AIDS enrolled in care. Advances in medical treatment have improved the life-limiting effects of the disease, though many chronic symptoms persist. Comprehensive care is critical to manage the diverse constellation of symptoms. However, many patients face challenges to receiving optimal care due to limited resources, mistrust of health care providers, and/or co-occurring medical, psychiatric, and substance use disorders...
May 1, 2018: Archives of Clinical Neuropsychology: the Official Journal of the National Academy of Neuropsychologists
https://www.readbyqxmd.com/read/29709586/large-group-size-promotes-the-evolution-of-cooperation-in-the-mutual-aid-game
#11
Hayato Shimura, Mayuko Nakamaru
Our society is based on group cooperation, but this remains an unsolved problem from the viewpoint of evolutionary biology and the social sciences. Group cooperation is often studied through the public goods game, and it has been shown that large group size never promotes the evolution of cooperation. We consider the mutual-aid game, in which one member of the group is chosen randomly as the aid recipient, and other members decide whether to help the recipient. This game can describe the early stage of insurance provision in England, for example...
April 27, 2018: Journal of Theoretical Biology
https://www.readbyqxmd.com/read/29708490/audiology-assistants-results-of-a-multicenter-survey
#12
Roanne Karzon, Lisa Hunter, Wendy Steuerwald
BACKGROUND: Although audiologists have been using support personnel for over 45 yr, controversy and variability continue with respect to the entry-level education, training methods, and scope of practice. PURPOSE: As part of a larger clinical practices survey, this report focuses on use of audiology assistants (AAs) for pediatric settings and "life-span" facilities that had a significant population of pediatric patients. RESEARCH DESIGN: A questionnaire was sent to 116 facilities in geographically diverse locations...
May 2018: Journal of the American Academy of Audiology
https://www.readbyqxmd.com/read/29703099/hearing-tests-are-just-child-s-play-the-sound-scouts-game-for-children-entering-school
#13
Harvey Dillon, Carolyn Mee, Jesus Cuauhtemoc Moreno, John Seymour
OBJECTIVE: To create a hearing test useable without the involvement of a clinician or calibrated equipment, suitable for children aged 5 or older. DESIGN: The tablet-based app (Sound Scouts) includes tests of speech in quiet, speech in noise and tones in noise, all embedded in game designed to maintain attention. Data were collected to intelligibility-equalize the stimuli, establish normative performance, and evaluate the sensitivity with which Sound Scouts detected known hearing problems and identified their type...
April 27, 2018: International Journal of Audiology
https://www.readbyqxmd.com/read/29702567/a-perspective-on-the-application-of-spatially-resolved-arpes-for-2d-materials
#14
REVIEW
Mattia Cattelan, Neil A Fox
In this paper, a perspective on the application of Spatially- and Angle-Resolved PhotoEmission Spectroscopy (ARPES) for the study of two-dimensional (2D) materials is presented. ARPES allows the direct measurement of the electronic band structure of materials generating extremely useful insights into their electronic properties. The possibility to apply this technique to 2D materials is of paramount importance because these ultrathin layers are considered fundamental for future electronic, photonic and spintronic devices...
April 27, 2018: Nanomaterials
https://www.readbyqxmd.com/read/29696326/access-to-orthopaedic-surgical-care-in-northern-tanzania-a-modelling-study
#15
Ajay Premkumar, Xiaohan Ying, W Mack Hardaker, Honest H Massawe, David J Mshahaba, Faiton Mandari, Anthony Pallangyo, Rogers Temu, Gileard Masenga, David A Spiegel, Neil P Sheth
BACKGROUND: The global burden of musculoskeletal disease and resulting disability is enormous and is expected to increase over the next few decades. In the world's poorest regions, the paucity of information defining and quantifying the current state of access to orthopaedic surgical care is a major problem in developing effective solutions. This study estimates the number of individuals in Northern Tanzania without adequate access to orthopaedic surgical services. METHODS: A chance tree was created to model the probability of access to orthopaedic surgical services in the Northern Tanzanian regions of Arusha, Kilimanjaro, Tanga, Singida, and Manyara, with respect to four dimensions: timeliness, surgical capacity, safety, and affordability...
April 25, 2018: World Journal of Surgery
https://www.readbyqxmd.com/read/29695069/mobile-exergaming-in-adolescents-everyday-life-contextual-design-of-where-when-with-whom-and-how-the-smartlife-case
#16
Ayla Schwarz, Ann DeSmet, Greet Cardon, Sebastien Chastin, Ruben Costa, António Grilo, Josue Ferri, Jorge Domenech, Jeroen Stragier
Exergames, more specifically console-based exergames, are generally enjoyed by adolescents and known to increase physical activity. Nevertheless, they have a reduced usage over time and demonstrate little effectiveness over the long term. In order to increase playing time, mobile exergames may increase potential playing time, but need to be engaging and integrated in everyday life. The goal of the present study was to examine the context of gameplay for mobile exergaming in adolescents’ everyday life to inform game design and the integration of gameplay into everyday life...
April 24, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29683929/18f-fdg-pet-ct-in-the-evaluation-of-cancer-cervix-where-do-we-stand-today
#17
Shanmuga S Palaniswamy, Chaitanya R Borde, Padma Subramanyam
The incidence of gynecological malignancies is on the rise partly because of the availability of screening programmes, awareness, higher technological advancements, and availability of better medical care. Early diagnosis of any malignancy leads to prompt treatment. Use of 18Fluorine-Fluorodeoxyglucose (F-FDG) PET/CT in the treatment and follow-up of patients with Ca cervix considerably improves patient management. The primary diagnosis of Ca cervix is made either by biopsy of a visible tumor on the cervix or by a cone biopsy of a nonvisible malignant cervical focus...
April 20, 2018: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/29680803/review-of-economic-evaluations-of-teleophthalmology-as-a-screening-strategy-for-chronic-eye-disease-in-adults
#18
Noha Sharafeldin, Atsushi Kawaguchi, Aishwarya Sundaram, Sandy Campbell, Chris Rudnisky, Ezekiel Weis, Matthew T S Tennant, Karim F Damji
BACKGROUND/AIMS: Teleophthalmology is well positioned to play a key role in screening of major chronic eye diseases. Economic evaluation of cost-effectiveness of teleophthalmology, however, is lacking. This study provides a systematic review of economic studies of teleophthalmology screening for diabetic retinopathy (DR), glaucoma and macular degeneration. METHODS: Structured search of electronic databases and full article review yielded 20 cost-related articles...
April 21, 2018: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/29680110/increase-in-physical-activity-sustained-1-year-after-playground-intervention
#19
Madeline C Frost, Elena S Kuo, Lisa T Harner, Kelly R Landau, Katie Baldassar
INTRODUCTION: Regular physical activity is a vital component of child health, and schools play an important role in the promotion of physical activity among children. This paper describes the implementation and evaluation of a playground redesign involving structural and loose play equipment to increase students' physical activity at an intermediate school in Leadville, Colorado. METHODS: Direct observations were conducted during recess before the redesign in May 2014, then again at 6 months and 1 year after the redesign...
May 2018: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/29674288/a-flexible-wearable-sensor-for-knee-flexion-assessment-during-gait
#20
Enrica Papi, Yen Nee Bo, Alison H McGregor
BACKGROUND: Gait analysis plays an important role in the diagnosis and management of patients with movement disorders but it is usually performed within a laboratory. Recently interest has shifted towards the possibility of conducting gait assessments in everyday environments thus facilitating long-term monitoring. This is possible by using wearable technologies rather than laboratory based equipment. RESEARCH QUESTION: This study aims to validate a novel wearable sensor system's ability to measure peak knee sagittal angles during gait...
April 13, 2018: Gait & Posture
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