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https://www.readbyqxmd.com/read/29454305/psychotropic-and-anti-dementia-treatment-in-elderly-persons-with-clinical-signs-of-dementia-with-lewy-bodies-a-cross-sectional-study-in-40-nursing-homes-in-sweden
#1
Iris Zahirovic, Gustav Torisson, Carina Wattmo, Elisabet Londos
BACKGROUND: Elderly persons with a dementia diagnosis often suffer from different neuropsychiatric symptoms (NPS) such as delusions, hallucinations, depression, anxiety, irritability and agitation. Currently, the medical treatment for NPS consists mostly of psychotropic medication such as hypnotics/sedatives, anxiolytics and antipsychotics. In elderly persons with dementia, usage of antipsychotics is less appropriate because of the risk of side effects such as parkinsonism, rapid cognitive decline, cerebrovascular events and finally mortality...
February 17, 2018: BMC Geriatrics
https://www.readbyqxmd.com/read/29452296/development-and-persistence-of-suspected-neuropathic-pain-after-total-knee-arthroplasty-in-individuals-with-osteoarthritis
#2
Matthew Fitzsimmons, Eloise Carr, Linda Woodhouse, Geoff P Bostick
BACKGROUND: Despite the effectiveness of total knee arthroplasty (TKA) for osteoarthritis (OA), up to 20% will report knee pain 1-year after surgery. One possible reason is the development of neuropathic pain before or after TKA. OBJECTIVE: To longitudinally describe suspected neuropathic pain in patients pre- and post-TKA and to explore relationships between pre-TKA suspected neuropathic pain and post-TKA outcomes. DESIGN: Prospective observational study...
February 13, 2018: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/29435648/interleukin-6-and-complement-serum-level-study-in-parkinson-s-disease
#3
Branislav Veselý, Michal Dufek, Vojtech Thon, Miroslav Brozman, Silvia Királová, Tatiana Halászová, Eva Koriťáková, Ivan Rektor
The objective of this study is to assess whether elevation of serum inflammatory markers levels may indicate the progression of clinical impairment in Parkinson's disease (PD) patients. In 47 PD patients, the serum levels of the C3 and C4 part of the complement and Interleukin-6 (IL-6) were measured. The results at baseline and after 2 years were correlated with scales measuring memory, depression, motor symptoms, and quality of life. Patients with higher levels of C3 and C4 at baseline had decreased quality of life, verbal ability, and memory...
February 12, 2018: Journal of Neural Transmission
https://www.readbyqxmd.com/read/29420786/one-day-behavioral-intervention-for-distressed-veterans-with-migraine-results-of-a-multimethod-pilot-study
#4
C Huddleston, L Martin, K Woods, L Dindo
Introduction: Migraine, a chronic neurological disorder characterized by episodic severe headache pain and functional impairment, affects approximately 12% of the general US population. Veterans returning from Iraq or Afghanistan have two to four times the incidence of migraine of the general population. Veterans with migraines are more than twice as likely to have comorbid psychiatric conditions as veterans without migraines, with depression and post-traumatic stress disorder being most prevalent...
February 6, 2018: Military Medicine
https://www.readbyqxmd.com/read/29411996/emergence-of-depressive-symptoms-from-kindergarten-to-sixth-grade
#5
Gretchen R Gudmundsen, Isaac C Rhew, Elizabeth McCauley, Jahun Kim, Ann Vander Stoep
This study documents the emergence of symptoms of anxiety and depression in a community sample of school-age children and describes the temporal progression of symptoms leading to depressive episodes. Caregivers of 468 seventh graders reported retrospectively the manifestation of 14 symptoms of depression and anxiety in their children from kindergarten through sixth grade. The sample was balanced by sex and reflected the racial and economic diversity of the urban school district. Childhood period prevalence was calculated for each symptom, and discrete time survival analyses compared likelihoods of early symptom emergence in children who did and did not meet diagnostic criteria for major depressive disorder (MDD) by ninth grade...
February 7, 2018: Journal of Clinical Child and Adolescent Psychology
https://www.readbyqxmd.com/read/29411732/street-drug-use-among-emergency-patients-in-a-public-hospital-in-turkey
#6
F T Caliskan, I Toker, R Toktas, Z Temizyurek, O Unek, B Zirek, O Karcioglu
BACKGROUND: Country-specific numbers of street drug (SD) users are well documented. However, little data exists regarding these patients' clinical presentations and outcomes in the emergency department (ED). Therefore, management of these patients in the emergency setting is still a subject of debate. OBJECTIVES: The aim of this study is to determine the symptoms and signs of SD users presenting to the ED, and to report the substances, treatments, and outcomes. MATERIALS AND METHODS: In this single-center study, symptoms, clinical findings, diagnoses, and outcomes of patients who reported to have used SDs or were diagnosed as SD users were investigated within a 1-year study period...
January 2018: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/29403123/perceptions-of-accredited-social-health-activists-on-depression-a-qualitative-study-from-karnataka-india
#7
Aruna Rose Mary Kapanee, K S Meena, Prasanthi Nattala, Narayana Manjunatha, Paulomi M Sudhir
Background: Depression is a significant public health concern in India, associated with a large treatment gap. Assessing perceptions of Accredited Social Health Activists (ASHAs) on depression can be invaluable as they are selected to work at the interface between their own communities and the health-care delivery system. Aims and Objectives: This study aimed at utilizing a qualitative approach to examine the ASHAs' understanding of depression, their mental health-care practices specific to depression, and their capacity-building needs with regard to identification and helping persons with depression...
January 2018: Indian Journal of Psychological Medicine
https://www.readbyqxmd.com/read/29397780/depressive-symptoms-affect-outcomes-of-pessary-use-in-postmenopausal-women-with-uterine-prolapse
#8
F-F Ai, L Zhu, M Mao, Y Zhang, J Kang
OBJECTIVE: This study aimed to investigate the impact of depressive symptoms on successful pessary treatment for postmenopausal women with symptomatic pelvic organ prolapse (POP). METHODS: We performed a prospective study involving postmenopausal women with POP who visited our clinic seeking pessary treatment. Demographic information and medical histories were collected. The participants completed the following questionnaires at baseline and after 3 months of successful pessary use: (1) the Pelvic Floor Impact Questionnaire-7 (PFIQ-7); (2) the Pelvic Floor Distress Inventory (PFDI-20); and (3) the Patient Health Questionnaire-9 (PHQ-9)...
February 3, 2018: Climacteric: the Journal of the International Menopause Society
https://www.readbyqxmd.com/read/29394208/caring-interactions-in-secondary-prevention-programs-a-qualitative-inquiry-of-individuals-with-parkinson-s-disease
#9
Lindsey E Greviskes, Leslie Podlog, Maria Newton, Leland E Dibble, Ryan D Burns, Wanda Pillow, Morgan S Hall, Christopher Hammer
BACKGROUND AND PURPOSE: With Parkinson's disease (PD) prevalence rates steadily increasing and long-term adherence to regular physical activity and exercise often difficult to achieve, it is imperative to investigate factors promoting adherence to secondary prevention programs (SPP) that help limit the progression of motor and nonmotor signs and symptoms of the disease. Caring interactions between patients and their rehabilitation team may be particularly germane to individuals with PD, given the physical and psychosocial issues that often accompany this disease (eg, loss of physical function, depression, apathy, and cognitive impairments)...
February 1, 2018: Journal of Geriatric Physical Therapy
https://www.readbyqxmd.com/read/29391860/the-relationship-between-ocular-itch-ocular-pain-and-dry-eye-symptoms-an-american-ophthalmological-society-thesis
#10
Anat Galor, Leslie Small, William Feuer, Roy C Levitt, Konstantinos D Sarantopoulos, Gil Yosipovitch
Purpose: To evaluate associations between sensations of ocular itch and dry eye (DE) symptoms, including ocular pain, and DE signs. Methods: A cross-sectional study of 324 patients seen in the Miami Veterans Affairs eye clinic was performed. The evaluation consisted of questionnaires regarding ocular itch, DE symptoms, descriptors of neuropathic-like ocular pain (NOP), and evoked pain sensitivity testing on the forehead and forearm, followed by a comprehensive ocular surface examination including corneal mechanical sensitivity testing...
August 2017: Transactions of the American Ophthalmological Society
https://www.readbyqxmd.com/read/29360583/is-psychiatric-depression-a-presenting-neurologic-sign-of-meningioma-a-critical-review-of-the-literature-with-causative-etiology
#11
REVIEW
Remi A Kessler, Joshua Loewenstern, Karan Kohli, Raj K Shrivastava
Benign meningiomas constitute 80-90% of all meningiomas, and represent the most common type of central nervous system (CNS) tumor in adults. The vast majority of meningiomas are minimally symptomatic or asymptomatic early in their onset and thereby can often result in delayed diagnosis. Early diagnosis of meningioma is critical as it can maximize treatment options and improve outcomes and survival. While seizures and focal neurological deficits are considered to be the most prevalent symptoms, depression may also be an important and significant sign...
January 19, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29331872/effect-of-physical-activity-on-cognitive-flexibility-depression-and-rbd-in-healthy-elderly
#12
Stefanie Lerche, Alexandra Gutfreund, Kathrin Brockmann, Markus A Hobert, Isabel Wurster, Ulrike Sünkel, Gerhard W Eschweiler, Florian G Metzger, Walter Maetzler, Daniela Berg
OBJECTIVE: The prevalence of Alzheimer's disease and Parkinson's disease increases with the raising number of elderly, which will be a challenging situation for the healthcare systems and society in the future. There is evidence that there are modifiable risk-factors e.g. physical activity for these diseases. Here, we study the interaction between sports inactivity with prodromal markers for neurodegeneration. PATIENTS AND METHODS: We investigated 667 neurologically healthy individuals cross-sectional and a subgroup longitudinal over six years...
January 9, 2018: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29305081/extending-knowledge-of-the-clinical-picture-of-balkan-adder-vipera-berus-bosniensis-envenoming-the-first-photographically-documented-neurotoxic-case-from-south-western-hungary
#13
Csaba Varga, Tamás Malina, Viktória Alföldi, Gergely Bilics, Ferenc Nagy, Tibor Oláh
We report a severe envenoming associated with minimal local symptoms following a Balkan adder (Vipera berus bosniensis) bite in South-Western Hungary. A 63-year-old male with a history of hypertension and sinus bradycardia (45/min) was bitten by a sub-adult specimen of V. b. bosniensis in Somogy County on 04 May 2017. The patient was transported to and treated at the Emergency Department of Somogy County "Moritz Kaposi" General Hospital, Kaposvár. Locally only pain and minimal swelling with a small haematoma developed on the bitten finger...
January 2, 2018: Toxicon: Official Journal of the International Society on Toxinology
https://www.readbyqxmd.com/read/29303703/reasons-for-inactive-disease-and-flare-in-systemic-onset-juvenile-idiopathic-arthritis-patients-during-tocilizumab-treatment
#14
Mikhail M Kostik, Eugenia A Isupova, Irina A Chikova, Margarita F Dubko, Vera V Masalova, Ludmila S Snegireva, Olga V Kalashnikova, Vyacheslav G Chasnyk
OBJECTIVES: The aim of our study was to evaluate disease courses and outcomes of sJIA children undergoing tocilizumab (TCZ) treatment, and to establish the predictors which distinguish inactive disease and disease flares. METHODS: Our retrospective study included 48 active sJIA children who were refractory to different anti-rheumatic drugs and who were then started on TCZ. The effectiveness of TCZ was assessed by the changes of sJIA attributed signs and symptoms and the remission was judged according to the Wallace (2004) criteria...
December 15, 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/29301414/helping-dementia-caregivers-manage-medical-problems-benefits-of-an-educational-resource
#15
Sheryl Zimmerman, Philip D Sloane, Kimberly Ward, Anna Beeber, David Reed, Christine Lathren, Bobbi Matchar, Lisa Gwyther
BACKGROUND/RATIONALE: Family caregivers of people with dementia must attend to medical care needs of their relative, yet few available resources address comorbidities in dementia. Consequently, caregivers feel ill-equipped when medical concerns arise. In response, an educational resource-Alzheimer's Medical Advisor ( AlzMed)-was developed in 2 forms (website and book) and evaluated. METHODS: Family caregivers (143 website and 51 book) used an educational resource that provides information on medical problems, vital signs, pain, dehydration, and the healthcare system...
January 1, 2018: American Journal of Alzheimer's Disease and Other Dementias
https://www.readbyqxmd.com/read/29289498/the-mental-health-of-elite-athletes-in-the-united-kingdom
#16
R L Foskett, F Longstaff
OBJECTIVES: The purpose of this study was to investigate the prevalence of signs of anxiety/depression and distress among a sample of elite athletes in the United Kingdom (UK). A secondary aim was to identify the variables associated with signs of anxiety/depression and distress in the same sample. DESIGN: A cross-sectional survey was distributed to a sample of elite athletes in the UK. METHODS: A total of 143 elite athletes completed an online survey that consisted of demographic questions, the Greenhaus Scale assessing career satisfaction, the 12-Item General Health Questionnaire assessing signs of anxiety/depression and a distress screener based on the Four-Dimensional Symptom Questionnaire...
December 15, 2017: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/29286513/influence-of-polymorphic-variants-of-the-slc6a4-gene-on-the-frequency-of-detection-of-depressive-states-in-the-group-of-the-clean-up-workers-of-consequences-of-chornobyl-accident-in-the-remote-period-after-the-chornobyl-catastrophe
#17
I V Abramenko, N I Bilous, S A Chumak, K M Loganovsky
Mental disorders of the victims are one of the important medical consequences of the Chornobyl accident. It is also known that in the implementation of the pathogenesis of depressive states a significant role belongs to the sero tonin transporter gene (SLC6A4). OBJECTIVE: To determine the effect of polymorphic variants of the SLC6A4 gene on the frequency of detection of depression in a group of clean up workers in the remote period after the Chornobyl catastrophe. METHODS: The study was conducted in a group of 59 victims of the Chornobyl NPP accident, divided into two groups (without depression and with depressive symptoms)...
December 2017: Problemy Radiat︠s︡iĭnoï Medyt︠s︡yny Ta Radiobiolohiï
https://www.readbyqxmd.com/read/29278894/asymmetric-ataxia-depression-memory-loss-epilepsy-and-axonal-neuropathy-associated-with-a-heterozygous-dna-polymerase-gamma-variant-of-uncertain-significance-c1370g-a-r457q
#18
Nivedita U Jerath, Michael E Shy
INTRODUCTION: Mutations in the gene encoding DNA polymerase gamma (POLG) impair its ability to proofread mitochondrial DNA (mtDNA) during replication [1]. This results in a high frequency of randomly distributed mtDNA mutations and thus a wide range of phenotypes, including seizures, neuropathy, and cerebellar ataxia [1, 2]. We document a phenotype associated with the rare POLG variant c.1370G>A (p.R457Q). METHODS: Over 10 years, we performed electrodiagnostic and neuropsychologic on a patient who presented with a variety of neurologic symptoms...
December 20, 2017: Journal of Neuromuscular Diseases
https://www.readbyqxmd.com/read/29273669/recognition-of-mental-disorders-findings-from-a-cross-sectional-study-among-medical-students-in-singapore
#19
Louisa Picco, Esmond Seow, Boon Yiang Chua, Rathi Mahendran, Swapna Verma, Siow Ann Chong, Mythily Subramaniam
OBJECTIVES: To assess recognition of five mental disorders (alcohol abuse, dementia, depression, obsessive-compulsive disorder (OCD) and schizophrenia) among a sample of medical students using a vignette-based approach. Socio-demographic predictors of correct recognition were also explored. DESIGN: Cross-sectional online survey. PARTICIPANTS: Medical students studying in Singapore. METHODS: This was a cross-sectional online study among medical students (n=502) who were randomly assigned one of the five vignettes...
December 21, 2017: BMJ Open
https://www.readbyqxmd.com/read/29259553/indication-of-cognitive-change-and-associated-risk-factor-after-thoracic-surgery-in-the-elderly-a-pilot-study
#20
Kay Kulason, Rui Nouchi, Yasushi Hoshikawa, Masafumi Noda, Yoshinori Okada, Ryuta Kawashima
Background: This pilot study investigated the effects of partial pulmonary lobectomy lung surgery on cognitive functions of elderly Japanese patients. It is recognized that elderly patients undergoing surgery have increased risk of Postoperative Cognitive Decline (POCD), a condition in which learning, memory, and processing speed is greatly reduced after surgery. Since elderly patients are more likely to exhibit symptoms of POCD, the incidence is increasing as the population receiving surgery is aging. Methods: Cognitive function was measured for all subjects (n = 12) before and after surgery using three different cognitive tests: Mini-Mental Status Exam-Japanese (MMSE-J), Frontal Assessment Battery (FAB), and a computerized Cogstate Brief Battery (CBB)...
2017: Frontiers in Aging Neuroscience
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