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https://www.readbyqxmd.com/read/29679153/stigma-as-a-barrier-to-recognizing-personal-mental-illness-and-seeking-help-a-prospective-study-among-untreated-persons-with-mental-illness
#1
Georg Schomerus, Susanne Stolzenburg, Simone Freitag, Sven Speerforck, Deborah Janowitz, Sara Evans-Lacko, Holger Muehlan, Silke Schmidt
It is unclear to what extent failure to recognize symptoms as potential sign of a mental illness is impeding service use, and how stigmatizing attitudes interfere with this process. In a prospective study, we followed a community sample of 188 currently untreated persons with mental illness (predominantly depression) over 6 months. We examined how lack of knowledge, prejudice and discrimination impacted on self-identification as having a mental illness, perceived need, intention to seek help, and help-seeking, both with respect to primary care (visiting a general practitioner, GP) and specialist care (seeing a mental health professional, MHP)...
April 20, 2018: European Archives of Psychiatry and Clinical Neuroscience
https://www.readbyqxmd.com/read/29670407/first-episode-psychosis-as-the-initial-presentation-of-multiple-sclerosis-a-case-report
#2
Athena Enderami, Rose Fouladi, Seyed Hamzeh Hosseini
Background: Multiple sclerosis (MS) is an inflammatory disease that affects the central nervous system (CNS). MS with episode of psychosis is a rare entity, and to the best of our knowledge, no case has been reported from Iran till date. Case presentation: We report a case of MS with first-episode psychosis in a 27-year-old single man with no history of psychiatric disorder or drug abuse. The patient developed neurological symptoms after 3 months and was finally diagnosed as a case of MS...
2018: International Medical Case Reports Journal
https://www.readbyqxmd.com/read/29667796/isotretinoin-the-ups-are-just-as-troubling-as-the-downs
#3
Jay M Truitt, Jason S Reichenberg, Kevin G Sharghi, Shirlene M Sampson, Randall K Roenigk, Michelle Magid
INTRODUCTION: Isotretinoin, previously marketed as Accutane®, is an oral retinoid medication that is used to treat acne and other cutaneous disorders. Although the data is conflicting, previous reports suggest a causal relationship between isotretinoin and depression. When reviewing these previous reports, many patients who were diagnosed as 'depressed' did not undergo a thorough psychiatric evaluation and/or were not diagnosed according to the criteria of the Diagnostic and Statistical Manual of Mental Disorders (DSM)...
April 18, 2018: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/29663082/chemical-meningitis-from-a-leaking-craniopharyngioma-a-case-report
#4
David Hakizimana, Lars Poulsgaard, Kåre Fugleholm
Recurrent chemical meningitis from cyclic leakage of cyst content from a craniopharyngioma is a rare phenomenon. Here, we report a case of leaking cystic craniopharyngioma presenting with recurrent episodes of sterile meningitis, depression, and paranoia. The diagnosis after an initial craniotomy and exploration was hypophysitis. Signs and symptoms were not alleviated by puncture and biopsy of the tumour but they disappeared after complete resection with a final histological diagnosis of craniopharyngioma.
April 16, 2018: Acta Neurochirurgica
https://www.readbyqxmd.com/read/29655640/how-are-ocular-signs-and-symptoms-of-dry-eye-associated-with-depression-in-women-with-and-without-sj%C3%A3-gren-s-syndrome
#5
John A Gonzales, Annie Chou, Jennifer R Rose-Nussbaumer, Vatinee Y Bunya, Lindsey A Criswell, Caroline H Shiboski, Thomas M Lietman
PURPOSE: To determine whether ocular phenotypic features of keratoconjunctivitis sicca (KCS) and/or participant-reported symptoms of dry eye disease are associated with depression in women participants enrolled in the Sjögren's International Collaborative Clinical Alliance (SICCA). DESIGN: Cross-sectional study. METHODS: Women enrolled in the SICCA registry from 9 international research sites. Participants met at least one of five inclusion criteria for registry enrollment (including complaints of dry eyes or dry mouth, a previous diagnosis of Sjögren's syndrome (SS), abnormal serology (positive anti-Sjögren's syndrome-related antigen A and/or B (anti-SSA and/or anti-SSB), or elevated anti-nuclear antibody and rheumatoid factor), bilateral parotid gland enlargement, or multiple dental caries)...
April 12, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29655586/non-motor-outcomes-of-subthalamic-stimulation-in-parkinson-s-disease-depend-on-location-of-active-contacts
#6
Haidar Salimi Dafsari, Jan Niklas Petry-Schmelzer, K Ray-Chaudhuri, Keyoumars Ashkan, Luca Weis, Till A Dembek, Michael Samuel, Alexandra Rizos, Monty Silverdale, Michael T Barbe, Gereon R Fink, Julian Evans, Pablo Martinez-Martin, Angelo Antonini, Veerle Visser-Vandewalle, Lars Timmermann
BACKGROUND: Subthalamic nucleus (STN) deep brain stimulation (DBS) improves quality of life (QoL), motor, and non-motor symptoms (NMS) in Parkinson's disease (PD). Few studies have investigated the influence of the location of neurostimulation on NMS. OBJECTIVE: To investigate the impact of active contact location on NMS in STN-DBS in PD. METHODS: In this prospective, open-label, multicenter study including 50 PD patients undergoing bilateral STN-DBS, we collected NMSScale (NMSS), NMSQuestionnaire (NMSQ), Hospital Anxiety and Depression Scale (anxiety/depression, HADS-A/-D), PDQuestionnaire-8 (PDQ-8), Scales for Outcomes in PD-motor examination, motor complications, activities of daily living (ADL), and levodopa equivalent daily dose (LEDD) preoperatively and at 6 months follow-up...
March 16, 2018: Brain Stimulation
https://www.readbyqxmd.com/read/29629061/depression-from-the-perspective-of-modern-and-persian-medicine
#7
Majid Anushiravani, Ali Akhondpour Manteghi, Ali Taghipur, Mahdi Eslami
Background: Depression is one of the five most-common diseases globally, and is expected to be the second leading cause of disability by 2020 and its economic and social burden is a major problem worldwide. Objective: The aim of this research was to elucidate the causes and symptoms of depression according to Persian Medicine (PM) and classic medicine. Methods: In this study, works that were investigated were the Canon of Medicine , Al-Hawi Fi Teb , Kamel Al-Sina'a , Zakhireh Kharazmshahi and Exir A'azam ...
February 2018: Electronic Physician
https://www.readbyqxmd.com/read/29622276/prospective-assessment-of-patient-reported-outcomes-in-gynecologic-cancer-patients-before-and-after-pelvic-exenteration
#8
Shannon D Armbruster, Charlotte C Sun, Shannon N Westin, Diane C Bodurka, Lois Ramondetta, Larissa A Meyer, Pamela T Soliman
OBJECTIVE: Pelvic exenteration (PE) is a surgical procedure associated with significant morbidity offered to select women with locally advanced or recurrent gynecologic cancers. This ongoing study examines an array of patient-reported outcomes and satisfaction with PE. METHODS: Since February 2009, prospectively enrolled participants completed questionnaires evaluating body image (BIS), depression (CESD), social support (DUFSS), symptoms (MDASI), sexual function (SAQ), functional status (SF-12), quality of life (The Stoma-QOL), satisfaction with decision (SWD) and an investigator-designed survey at baseline, 6, and 12months after PE...
April 2, 2018: Gynecologic Oncology
https://www.readbyqxmd.com/read/29619099/the-impact-of-deep-brain-stimulation-on-the-quality-of-life-and-swallowing-in-individuals-with-parkinson-s-disease
#9
Maira Rozenfel Olchik, Marciéle Ghisi, Annelise Ayres, Arthur Francisco Shumacher Schuh, Paulo Petry Oppitz, Carlos Roberto de Mello Rieder
Introduction  Deep brain stimulation (DBS) is an established treatment for Parkinson's disease (PD). However, there is little evidence regarding the effect of DBS on dysphagia. Objective  To assess the swallowing and quality of life of individuals with PD before and after DBS surgery. Methods  Our sample consisted of people who had undergone DBS surgery in a referral hospital in the state of Rio Grande do Sul, Brazil. The inclusion criteria were a diagnosis of PD and having undergone DBS surgery. A cognitive screening, through a questionnaire about depression and quality of life, was conducted...
April 2018: International Archives of Otorhinolaryngology
https://www.readbyqxmd.com/read/29611892/mlc901-neuroaid-ii-%C3%A2-for-cognition-after-traumatic-brain-injury-a-pilot-randomised-clinical-trial
#10
Alice Theadom, Suzanne Barker-Collo, Kelly M Jones, Priya Parmar, Rohit Bhattacharjee, Valery L Feigin
BACKGROUND: Treatments to facilitate recovery after traumatic brain injury (TBI) are urgently needed. To examine the safety and potential effects of herbal supplement MLC901 (NeuroAiD IITM ) on cognitive functioning following TBI, we conducted a nine-month pilot, randomised placebo-controlled clinical trial. METHODS: Adults aged 18-65 years, 1-12-months post-mild or moderate TBI, were randomised to receive MLC901 (0.8g capsules/day) or placebo for 6-months. The primary outcome was cognitive functioning assessed by the CNS-Vital Signs online neuropsychological test...
April 3, 2018: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/29606956/cognitive-blackouts-in-mild-cognitive-impairment-and-alzheimer-s-dementia
#11
Georg Adler, Agnies Marczak, Jana Binder
Background: Cognitive blackouts, e.g. moments of amnesia, disorientation, or perplexity may be an early sign of incipient Alzheimer's dementia (AD). A short questionnaire, the checklist for cognitive blackouts (CCB), was evaluated cross-sectionally in users of a memory clinic. Methods: The CCB was performed in 130 subjects, who further underwent a neuropsychological and clinical examination. Subjective memory impairment and depressive symptoms were assessed. Differences in the CCB score between diagnostic groups and relationships with cognitive performance, depression, and subjective memory impairment were analyzed...
January 2018: Dementia and Geriatric Cognitive Disorders Extra
https://www.readbyqxmd.com/read/29606864/do-patients-and-carers-agree-on-symptom-burden-in-advanced-copd
#12
Emma Mi, Ella Mi, Gail Ewing, Patrick White, Ravi Mahadeva, A Carole Gardener, Morag Farquhar
Objective: Accurate informal carer assessment of patient symptoms is likely to be valuable for decision making in managing the high symptom burden of COPD in the home setting. Few studies have investigated agreement between patients and carers in COPD. We aimed to assess agreement between patients and carers on symptoms, and factors associated with disagreement in a population-based sample of patients with advanced COPD. Patients and methods: This was a prospective, cross-sectional analysis of data from 119 advanced COPD patients and their carers...
2018: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/29606318/kleine-levin-syndrome-a-neuropsychiatric-disorder
#13
REVIEW
I Arnulf, E Groos, P Dodet
Kleine-Levin syndrome (KLS) is a rare, relapsing-remitting disease that affects mostly adolescents. It is characterized by episodes lasting from 1 to several weeks, and comprises neurological (hypersomnia, confusion, slowness, amnesia) and neuropsychiatric symptoms (derealization and apathy). Some psychiatric symptoms (megaphagia, hypersexuality, anxiety, depressed mood, hallucinations, delusions) arise during episodes, albeit less frequently, while patients are normal between episodes. However, sudden severe (>18h/day of sleep) and recurrent hypersomnia helps to differentiate KLS from other psychiatric mimics...
March 30, 2018: Revue Neurologique
https://www.readbyqxmd.com/read/29605103/effects-of-adjunctive-n-acetylcysteine-on-depressive-symptoms-modulation-by-baseline-high-sensitivity-c-reactive-protein
#14
Mauro Porcu, Mariana Ragassi Urbano, Waldiceu A Verri, Decio Sabbatini Barbosa, Marcela Baracat, Heber Odebrecht Vargas, Regina Célia Bueno Rezende Machado, Rodrigo Rossetto Pescim, Sandra Odebrecht Vargas Nunes
Outcomes in a RCTs of 12 weeks of theclinical efficacy of N-acetylcysteine (NAC) as an adjunctive treatment on depression and anxiety symptoms and its effects on high-sensitivity C-reactive protein (hs-CRP) levels. A wide array of measures were made. The 17-item version of the Hamilton Depression Rating Scale (HDRS17); the Hamilton Anxiety Rating Scale (HAM-A); Sheehan Disability Scale; Quality of Life; Clinical Global Impression (CGI); anthropometrics measures; and vital signs and biochemical laboratory. There were no significant differences among the groups regarding demographic, clinical features, use of medication, metabolic syndrome and comorbidities...
March 13, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29593619/psychological-impact-of-stalking-on-male-and-female-health-care-professional-victims-of-stalking-and-domestic-violence
#15
Daniela Acquadro Maran, Antonella Varetto
The aim of this work was to investigate stalking experiences in a sample of Health Care Professionals, or HCPs, who experienced domestic violence in their previous relationships with an intimate romantic or non-romantic who had become their stalkers. A comparison between males and females was made to highlight the differences among the genders. The findings showed that, for the most part, the victims experienced stalking by a stalker that was not of the same gender. Moreover, the nature of the relationship was romantic, for the most part, for both female and male subjects, suggesting that the principal motivation of stalking is the disruption of an intimate relationship...
2018: Frontiers in Psychology
https://www.readbyqxmd.com/read/29577633/impact-of-pediatric-cancer-on-family-relationships
#16
Craig Erker, Ke Yan, Liyun Zhang, Kristin Bingen, Kathryn E Flynn, Julie Panepinto
Little is known about the impact of cancer on family relationships from the perspective of the pediatric cancer patient and their sibling(s). This study assessed and compared children's experiences of family relationships in patients receiving active cancer therapy, those who have completed therapy, and siblings. A cross-sectional study of children with cancer and their siblings aged 8-17 years old was conducted. Children completed the PROMIS Pediatric Family Relationships short form and the Depressive Symptoms, Anxiety, and Peer Relationships short forms...
March 25, 2018: Cancer Medicine
https://www.readbyqxmd.com/read/29554991/historical-precedents-for-the-dsm-iii-bereavement-exclusion-criteria-for-major-depression
#17
Kenneth S Kendler
BACKGROUND: I review the historical antecedents of the two key features of the bereavement exclusion (BE) for major depression (MD) criteria initially proposed in DSM-III: (i) a context-dependent approach to the evaluation of MD which required that the diagnosis be given only when course, symptoms and signs are 'out of proportion' to experienced adversities, and (ii) bereavement is the sole adversity for which this context-dependent approach should be utilized. METHODS: A review of 49 textbook and review articles on depression or melancholia published 1880-1960...
March 20, 2018: Psychological Medicine
https://www.readbyqxmd.com/read/29554984/sensitivity-and-specificity-of-the-akena-visual-depression-inventory-avidi-18-in-kampala-uganda-and-cape-town-south-africa
#18
Dickens Akena, John Joska, Dan J Stein
BACKGROUND: Visual scales may be particularly useful in screening for depression in patients with low literacy. However, few have been validated and none are in common use. Aim Modification and validation of a visual scale to screen for depression in low literacy settings. METHOD: We assessed the validity, reliability and factor loading of a 28-item visual depression inventory using pictorial items depicting depression signs and symptoms. We validated a revised scale comprised of 18 items known as the Akena Visual Depression Inventory (AViDI-18) against a structured diagnostic interview (Mini-International Neuropsychiatric Inventory) in 343 patients in Kampala (Uganda) and Cape Town (South Africa)...
March 20, 2018: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/29544459/a-survey-of-subjective-constipation-in-parkinson-s-disease-patients-in-shanghai-and-literature-review
#19
Jing Gan, Ying Wan, Junjie Shi, Mingzhu Zhou, Zhiyin Lou, Zhenguo Liu
BACKGROUND: Constipation is one of the most frequent non-motor symptoms (NMS) in Parkinson's disease (PD) and the prevalence of constipation in PD patients varies among different studies. We designed this study to survey the prevalence and clinical characteristics of subjective constipation and the appearance chronology between the emergence of constipation and onset of motor symptoms in PD patients from Shanghai, China. METHODS: 268 PD patients were continuously recruited into this study...
March 15, 2018: BMC Neurology
https://www.readbyqxmd.com/read/29542093/posterior-limb-of-the-internal-capsule-predicts-poor-quality-of-life-in-patients-with-parkinson-s-disease-connectometry-approach
#20
Farzaneh Ghazi Sherbaf, Mahtab Mojtahed Zadeh, Maryam Haghshomar, Mohammad Hadi Aarabi
Psychiatric symptoms and motor impairment are major contributions to the poor quality of life in patients with Parkinson's disease (PD). Here, we applied a novel diffusion-weighted imaging approach, diffusion MRI connectometry, to investigate the correlation of quality of life, evaluated by Parkinson's Disease Questionnaire (PDQ39) with the white matter structural connectivity in 27 non-demented PD patients (disease duration of 5.3 ± 2.9 years, H and Y stage = 1.5 ± 0.6, UPDRS-III = 13.7 ± 6.5, indicating unilateral and mild motor involvement)...
March 14, 2018: Acta Neurologica Belgica
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