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JOURNAL ARTICLE
Benjamin R Slavin, Moses I Markowitz, Kevin M Klifto, Frank J Prologo, Susan M Taghioff, A Lee Dellon
BACKGROUND: Cryoanalgesia is a tool being used by interventional radiology to treat chronic pain. Within a certain cold temperature range, peripheral nerve function is interrupted, and recovers, without neuroma formation. Cryoanalgesia has most often been applied to the intercostal nerve. Cryoanalgesia has applications to peripheral nerve surgery, yet is poorly understood by reconstructive microsurgeons. METHODS: Histopathology of nerve injury was reviewed to understand cold applied to peripheral nerve...
September 26, 2023: Journal of Reconstructive Microsurgery
#22
JOURNAL ARTICLE
Razak M Gyasi, Julius Odei, Mohammed Gazali Hambali, Nelson Gyasi-Boadu, Bernard Obeng, Moses Asori, André Hajek, Louis Jacob, Yvonne Ami Dodzi Adjakloe, Jones Opoku-Ware, Lee Smith, Ai Koyanagi
OBJECTIVES: Literature linking diabetes mellitus (DM) to functional status is limited in low- and middle-income countries. Importantly, factors influencing this association are even less understood. This study aims to examine the association of DM with functional limitations (FL) in older adults and to identify potential factors influencing this association. METHODS: In a cross-sectional analysis, we examined the association between DM and basic and instrumental activities of daily living-related FL in 1201 adults aged ≥50 years from the Aging, Health, Psychological Well-being, and Health-seeking Behavior Study...
August 30, 2023: Journal of Psychosomatic Research
#23
JOURNAL ARTICLE
Hyeon Chang Kim, Hokyou Lee, Hyeok-Hee Lee, Gabin Lee, Eunji Kim, Moses Song, Jenny Moon, Yeeun Seo
BACKGROUND: The Korean Society of Hypertension has published the Korea Hypertension Fact Sheet 2022 to provide an overview of the magnitude and management status of hypertension and their recent trends. METHODS: The Fact Sheets were based on the analyses of Korean adults aged 20 years or older of the 1998-2020 Korea National Health and Nutrition Examination Survey and the 2002-2020 National Health Insurance Big Data. RESULTS: As of 2020, 29...
August 15, 2023: Clinical Hypertension
#24
REVIEW
Zahra Waheed, Faiza Amatul-Hadi, Amritpal Kooner, Muhammad Afzal, Rahma Ahmed, Harshawardhan Pande, Moses Alfaro, Amber Lee, Joravar Bhatti
Obesity has long been linked to adverse health effects over time. As the prevalence of obesity continues to rise, it is important to anticipate and minimize the complications that obesity brings in the anesthesia setting during surgery. Anesthetic departments must recognize the innumerable risks when managing patients with obesity undergoing surgery, including anatomical and physiological changes as well as comorbidities such as diabetes, cardiovascular diseases, and malignancies. Therefore, the purpose of this review is to analyze the current literature and evaluate the current and recent advances in anesthetic care of obese patients undergoing surgery, to better understand the specific challenges this patient population faces...
July 2023: Curēus
#25
EDITORIAL
Shui-Shan Lee, Moses John Bockarie, Jaffar A Al-Tawfiq
No abstract text is available yet for this article.
September 2023: International Journal of Infectious Diseases: IJID
#26
David Kim, Tetsuo Horimatsu, Mourad Ogbi, Brandee Goo, Hong Shi, Praneet Veerapaneni, Ronnie Chouhaita, Mary Moses, Rosaria Prasad, Tyler W Benson, Ragheb Harb, Ghaith Aboud, Hunter Seller, Steve Haigh, David J Fulton, Gábor Csányi, Yuqing Huo, Xiaochun Long, Philip Coffey, Richard Lee, Avirup Guha, Darryl Zeldin, Sung Hee Hwang, Bruce D Hammock, Neal L Weintraub, Ha Won Kim
INTRODUCTION: Inflammation is a key pathogenic feature of abdominal aortic aneurysm (AAA). Soluble epoxide hydrolase (sEH) is a pro-inflammatory enzyme that converts cytochrome P450-derived epoxides of fatty acids to the corresponding diols, and pharmacological inhibition of sEH prevented AAA formation. Both cytochrome P450 enzymes and sEH are highly expressed in the liver. Here, we investigated the role of hepatic sEH in AAA using a selective pharmacological inhibitor of sEH and hepatocyte-specific Ephx2 (which encodes sEH gene) knockout (KO) mice in two models of AAA [angiotensin II (AngII) infusion and calcium chloride (CaCl 2 ) application]...
July 11, 2023: bioRxiv
#27
JOURNAL ARTICLE
Zarina Akbary, Honglin Yu, Ivelisse Lorenzo, Karyme Paez, Narisa Diana Lee, Kayla DeBeVoise, Joel Moses, Nathaniel Sanders, Neal Connors, Adam Cassano
Aldo-keto reductases remain enzymes of interest in biocatalysis due to their ability to reduce carbonyls to alcohols stereospecifically. Based on genomic sequence, we identified aldo-keto reductases of a S. cerevisiae strain extracted from an ancient amber sample. One of the putative enzymes, AKR 163, displays 99% identity with α-amide ketoreductases from the S288C and YJM248 S. cerevisiae strains, which have been investigated for biocatalytic applications. To further investigate AKR 163, we successfully cloned, expressed in E...
July 15, 2023: Biochemical and Biophysical Research Communications
#28
Franck Rapaport, Kenneth Seier, Yaseswini Neelamraju, Duane Hassane, Timour Baslan, Daniel T Gildea, Samuel Haddox, Tak Lee, H Moses Murdock, Caroline Sheridan, Alexis Thurmond, Ling Wang, Martin Carroll, Larry D Cripe, Hugo Fernandez, Christopher E Mason, Elisabeth Paietta, Gail J Roboz, Zhuoxin Sun, Martin S Tallman, Yanming Zhang, Mithat Gönen, Ross Levine, Ari M Melnick, Maria Kleppe, Francine E Garrett-Bakelman
No abstract text is available yet for this article.
July 6, 2023: Blood Cancer Journal
#29
JOURNAL ARTICLE
Yuvnik Trada, Paul Keall, Michael Jameson, Daniel Moses, Peter Lin, Phillip Chlap, Lois Holloway, Myo Min, Dion Forstner, Allan Fowler, Mark T Lee
OBJECTIVES: To test if tumour changes measured using combination of diffusion-weighted imaging (DWI) MRI and FDG-PET/CT performed serially during radiotherapy (RT) in mucosal head and neck carcinoma can predict treatment response. METHODS: Fifty-five patients from two prospective imaging biomarker studies were analysed. FDG-PET/CT was performed at baseline, during RT (week 3), and post RT (3 months). DWI was performed at baseline, during RT (weeks 2, 3, 5, 6), and post RT (1 and 3 months)...
July 5, 2023: European Radiology
#30
REVIEW
Kristin K Sellers, Joshua L Cohen, Ankit N Khambhati, Joline M Fan, A Moses Lee, Edward F Chang, Andrew D Krystal
Despite increasing prevalence and huge personal and societal burden, psychiatric diseases still lack treatments which can control symptoms for a large fraction of patients. Increasing insight into the neurobiology underlying these diseases has demonstrated wide-ranging aberrant activity and functioning in multiple brain circuits and networks. Together with varied presentation and symptoms, this makes one-size-fits-all treatment a challenge. There has been a resurgence of interest in the use of neurostimulation as a treatment for psychiatric diseases...
June 27, 2023: Neuropsychopharmacology
#31
JOURNAL ARTICLE
Michele-Lee Moore, Lauren Hermanus, Scott Drimie, Loretta Rose, Mandisa Mbaligontsi, Hillary Musarurwa, Moses Ogutu, Khanyisa Oyowe, Per Olsson
UNLABELLED: COVID-19 posed threats for health and well-being directly, but it also revealed and exacerbated social-ecological inequalities, worsening hunger and poverty for millions. For those focused on transforming complex and problematic system dynamics, the question was whether such devastation could create a formative moment in which transformative change could become possible. Our study examines the experiences of change agents in six African countries engaged in efforts to create or support transformative change processes...
June 14, 2023: Sustainability Science
#32
JOURNAL ARTICLE
Stephen Kiboneka, Aggrey Anok, Regina Nakabuye, Silas Odiya, Julius Magembe, Rose Nazziwa, Charles Ddamulira, Andrew Mulooki, Ronald Moses Galiwango, Stephen Watya, Philip S Li, Richard K Lee, Ronald H Gray, Godfrey Kigozi, Edward Nelson Kankaka
OBJECTIVES: The objective of this study is to determine the optimal timing for device-based infant circumcision under topical anaesthesia. SUBJECTS/PATIENTS: We include infants aged 1-60 days who were enrolled in a field study of the no-flip ShangRing device at four hospitals in the Rakai region of south-central Uganda, between 5 February 2020 and 27 October 2020. METHODS: Two hundred infants, aged 0-60 days, were enrolled, and EMLA cream was applied on the foreskin and entire penile shaft...
July 2023: BJUI compass
#33
JOURNAL ARTICLE
Yuvnik Trada, Mark T Lee, Michael G Jameson, Phillip Chlap, Paul Keall, Daniel Moses, Peter Lin, Allan Fowler
BACKGROUND: The aim of this study was to measure functional changes in parotid glands using mid-treatment FDG-PET/CT and correlate early imaging changes to subsequent xerostomia in mucosal head and neck squamous cell carcinoma patients undergoing radiotherapy. MATERIALS AND METHODS: 56 patients from two prospective imaging biomarker studies underwent FDG-PET/CT at baseline and during radiotherapy (week 3). Both parotid glands were volumetrically delineated at each time point...
June 15, 2023: Radiotherapy and Oncology
#34
JOURNAL ARTICLE
Moses Lee, Sang Mee Hwang, Jong Sun Park, Jae Hyeon Park, Jeong Su Park
Lophomonas blattarum is an anaerobic protozoan living in the intestine of cockroaches and house dust mites, with ultramicroscopic characteristics such as the presence of a parabasal body, axial filament, and absence of mitochondria. More than 200 cases of Lophomonas infection of the respiratory tract have been reported worldwide. However, the current diagnosis of such infection depends only on light microscopic morphological findings from respiratory secretions. In this study, we attempted to provide more robust evidence of protozoal infection in an immunocompromised patient with atypical pneumonia, positive for Lophomonas-like protozoal cell forms...
May 2023: Parasites Hosts Dis
#35
JOURNAL ARTICLE
Yuvnik Trada, Peter Lin, Mark T Lee, Michael G Jameson, Phillip Chlap, Paul Keall, Daniel Moses, Allan Fowler
BACKGROUND: The aim of this study was to evaluate the impact of tumour region of interest (ROI) delineation method on mid-treatment 18 F-fluoro-2-deoxy-D-glucose positron emission tomography (FDG-PET) response prediction in mucosal head and neck squamous cell carcinoma during radiotherapy. METHODS: A total of 52 patients undergoing definitive radiotherapy with or without systemic therapy from two prospective imaging biomarker studies were analysed. FDG-PET was performed at baseline and during radiotherapy (week 3)...
May 1, 2023: Quantitative Imaging in Medicine and Surgery
#36
JOURNAL ARTICLE
Seong Won Lee, Woo Hun Choi, HyunHee Cho, Sang-Hun Lee, Wookyoung Choi, Jinsoo Joo, Donghun Lee, Su-Hyun Gong
Excitons, electron-hole pairs in semiconductors, can be utilized as information carriers with a spin or valley degree of freedom. However, manipulation of excitons' motion is challenging because of their charge-neutral characteristic and short recombination lifetimes. Here we demonstrate electric-field-driven drift and funneling of charged excitons (i.e., trions) toward the center of a MoSe2 monolayer. Using a simple bottom-gate device, we control the electric fields in the vicinity of the suspended monolayer, which increases the trion density and pulls down the layer...
May 11, 2023: Nano Letters
#37
JOURNAL ARTICLE
Wen-Wei Liao, Mobin Asri, Jana Ebler, Daniel Doerr, Marina Haukness, Glenn Hickey, Shuangjia Lu, Julian K Lucas, Jean Monlong, Haley J Abel, Silvia Buonaiuto, Xian H Chang, Haoyu Cheng, Justin Chu, Vincenza Colonna, Jordan M Eizenga, Xiaowen Feng, Christian Fischer, Robert S Fulton, Shilpa Garg, Cristian Groza, Andrea Guarracino, William T Harvey, Simon Heumos, Kerstin Howe, Miten Jain, Tsung-Yu Lu, Charles Markello, Fergal J Martin, Matthew W Mitchell, Katherine M Munson, Moses Njagi Mwaniki, Adam M Novak, Hugh E Olsen, Trevor Pesout, David Porubsky, Pjotr Prins, Jonas A Sibbesen, Jouni Sirén, Chad Tomlinson, Flavia Villani, Mitchell R Vollger, Lucinda L Antonacci-Fulton, Gunjan Baid, Carl A Baker, Anastasiya Belyaeva, Konstantinos Billis, Andrew Carroll, Pi-Chuan Chang, Sarah Cody, Daniel E Cook, Robert M Cook-Deegan, Omar E Cornejo, Mark Diekhans, Peter Ebert, Susan Fairley, Olivier Fedrigo, Adam L Felsenfeld, Giulio Formenti, Adam Frankish, Yan Gao, Nanibaa' A Garrison, Carlos Garcia Giron, Richard E Green, Leanne Haggerty, Kendra Hoekzema, Thibaut Hourlier, Hanlee P Ji, Eimear E Kenny, Barbara A Koenig, Alexey Kolesnikov, Jan O Korbel, Jennifer Kordosky, Sergey Koren, HoJoon Lee, Alexandra P Lewis, Hugo Magalhães, Santiago Marco-Sola, Pierre Marijon, Ann McCartney, Jennifer McDaniel, Jacquelyn Mountcastle, Maria Nattestad, Sergey Nurk, Nathan D Olson, Alice B Popejoy, Daniela Puiu, Mikko Rautiainen, Allison A Regier, Arang Rhie, Samuel Sacco, Ashley D Sanders, Valerie A Schneider, Baergen I Schultz, Kishwar Shafin, Michael W Smith, Heidi J Sofia, Ahmad N Abou Tayoun, Françoise Thibaud-Nissen, Francesca Floriana Tricomi, Justin Wagner, Brian Walenz, Jonathan M D Wood, Aleksey V Zimin, Guillaume Bourque, Mark J P Chaisson, Paul Flicek, Adam M Phillippy, Justin M Zook, Evan E Eichler, David Haussler, Ting Wang, Erich D Jarvis, Karen H Miga, Erik Garrison, Tobias Marschall, Ira M Hall, Heng Li, Benedict Paten
Here the Human Pangenome Reference Consortium presents a first draft of the human pangenome reference. The pangenome contains 47 phased, diploid assemblies from a cohort of genetically diverse individuals1 . These assemblies cover more than 99% of the expected sequence in each genome and are more than 99% accurate at the structural and base pair levels. Based on alignments of the assemblies, we generate a draft pangenome that captures known variants and haplotypes and reveals new alleles at structurally complex loci...
May 2023: Nature
#38
JOURNAL ARTICLE
Shang-Min Tsai, Elspeth K H Lee, Diana Powell, Peter Gao, Xi Zhang, Julianne Moses, Eric Hébrard, Olivia Venot, Vivien Parmentier, Sean Jordan, Renyu Hu, Munazza K Alam, Lili Alderson, Natalie M Batalha, Jacob L Bean, Björn Benneke, Carver J Bierson, Ryan P Brady, Ludmila Carone, Aarynn L Carter, Katy L Chubb, Julie Inglis, Jérémy Leconte, Michael Line, Mercedes López-Morales, Yamila Miguel, Karan Molaverdikhani, Zafar Rustamkulov, David K Sing, Kevin B Stevenson, Hannah R Wakeford, Jeehyun Yang, Keshav Aggarwal, Robin Baeyens, Saugata Barat, Miguel de Val-Borro, Tansu Daylan, Jonathan J Fortney, Kevin France, Jayesh M Goyal, David Grant, James Kirk, Laura Kreidberg, Amy Louca, Sarah E Moran, Sagnick Mukherjee, Evert Nasedkin, Kazumasa Ohno, Benjamin V Rackham, Seth Redfield, Jake Taylor, Pascal Tremblin, Channon Visscher, Nicole L Wallack, Luis Welbanks, Allison Youngblood, Eva-Maria Ahrer, Natasha E Batalha, Patrick Behr, Zachory K Berta-Thompson, Jasmina Blecic, S L Casewell, Ian J M Crossfield, Nicolas Crouzet, Patricio E Cubillos, Leen Decin, Jean-Michel Désert, Adina D Feinstein, Neale P Gibson, Joseph Harrington, Kevin Heng, Thomas Henning, Eliza M-R Kempton, Jessica Krick, Pierre-Olivier Lagage, Monika Lendl, Joshua D Lothringer, Megan Mansfield, N J Mayne, Thomas Mikal-Evans, Enric Palle, Everett Schlawin, Oliver Shorttle, Peter J Wheatley, Sergei N Yurchenko
Photochemistry is a fundamental process of planetary atmospheres that regulates the atmospheric composition and stability1 . However, no unambiguous photochemical products have been detected in exoplanet atmospheres so far. Recent observations from the JWST Transiting Exoplanet Community Early Release Science Program2,3 found a spectral absorption feature at 4.05 μm arising from sulfur dioxide (SO2 ) in the atmosphere of WASP-39b. WASP-39b is a 1.27-Jupiter-radii, Saturn-mass (0.28 MJ ) gas giant exoplanet orbiting a Sun-like star with an equilibrium temperature of around 1,100 K (ref...
April 26, 2023: Nature
#39
JOURNAL ARTICLE
Yekti Asih Purwestri, Yang-Seok Lee, Cathal Meehan, Windi Mose, Febri Adi Susanto, Putri Wijayanti, Anisa Nazera Fauzia, Tri Rini Nuringtyas, Nosheen Hussain, Hadi Lanang Putra, Jose Gutierrez-Marcos
BACKGROUND: Plants have the unique capability to form embryos from both gametes and somatic cells, with the latter process known as somatic embryogenesis. Somatic embryogenesis (SE) can be induced by exposing plant tissues to exogenous growth regulators or by the ectopic activation of embryogenic transcription factors. Recent studies have revealed that a discrete group of RWP-RK DOMAIN-CONTAINING PROTEIN (RKD) transcription factors act as key regulators of germ cell differentiation and embryo development in land plants...
April 19, 2023: BMC Plant Biology
#40
REVIEW
Michael G Rizzo, Moses I Markowitz, Arya Minaie, Dylan Greif, Danny Lee, Paul Allegra, Julianne Muñoz
PURPOSE: Clavicle fractures are among the most common orthopedic fractures, and treatment methods, operative versus nonoperative, have been a point of contention. The purpose of this study was to evaluate the 50 most influential articles regarding clavicle fractures to better understand past focuses of research and to identify any gaps in knowledge. METHODS: A review of the most cited articles related to clavicle fractures was conducted using Web of Science database...
April 4, 2023: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
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