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https://www.readbyqxmd.com/read/28638010/-evaluating-an-effectiveness-of-surgical-treatment-of-gastroesophageal-reflux-disease-combined-with-hiatal-hernia
#1
V V Mozharovskiy, A A Tsyganov, K V Mozharovskiy, A A Tarasov
AIM: To assess an effectiveness of surgical treatment of gastroesophageal reflux disease (GERD) combined with hiatal hernia (HH). MATERIAL AND METHODS: The trial included 96 patients with GERD and HH who were divided into 2 groups. The principal difference between groups was the use of surgery in the main group and therapeutic treatment in the comparison group. RESULTS: The effectiveness of surgical treatment is superior to therapeutic treatment of GERD by more than 2...
2017: Khirurgiia
https://www.readbyqxmd.com/read/28632697/increased-activity-in-the-lung-field-on-gastroesophageal-scintigraphy-is-not-always-due-to-aspiration
#2
Xiaofei Zhao, Hongming Zhuang
Elevated activity in the lung field on gastroesophageal scintigraphy (milk scan) generally indicates aspiration of the gastric content that has refluxed to the pharynx. An 18-year-old man underwent to gastroesophageal scintigraphy to assess the rate of gastric emptying. Increased activity was noted in the left lower lung field during the image acquisition. Careful analysis of the images showed that this activity was caused by hiatal herniation.
June 19, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28631878/gas-swallow-during-meals-in-patients-with-excessive-belching
#3
N Caballero, J Serra
BACKGROUND: Swallowed gas is an important source of abdominal gas, and aerophagia is often believed as a putative cause of gas-related abdominal symptoms. However, altered gas-swallow during meals has not been demonstrated. Our aim was to characterize the number of gas swallows during meals in patients complaining of excessive belching and gaseousness and a control group without abdominal symptoms during a 24-h period. METHODS: A 24-h pH-impedance monitoring was performed in 10 patients with excessive belching, and 11 patients without digestive symptoms or reflux in the pH-impedance study...
June 20, 2017: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/28625693/long-term-functional-outcomes-after-replacement-of-the-esophagus-in-pediatric-patients-a-systematic-literature-review
#4
REVIEW
Stefano Garritano, Tomoyuki Irino, Chiara Maria Scandavini, Andrianos Tsekrekos, Lars Lundell, Ioannis Rouvelas
BACKGROUND: The indications of esophageal replacement (ER) in pediatric patients include long gap esophageal atresia (LGEA), intractable post-corrosive esophageal strictures (PCES), and some rare esophageal diseases. Various conduits and procedures are currently used worldwide with a lack of consensus regarding the ideal substitute to replace the esophagus replacement. The short-term outcomes of these advanced procedures are well known; there are few data available describing long-term functional outcomes of these patients with long life expectancy...
June 8, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28623447/new-approaches-to-gastroesophageal-reflux-disease
#5
William Kethman, Mary Hawn
BACKGROUND: Gastroesophageal reflux disease (GERD) is the most common gastrointestinal disorder of the esophagus. It is a chronic, progressive disorder that presents most typically with heartburn and regurgitation and atypically with chest pain, dysphagia, chronic cough, globus, or sore throat. The mainstay for diagnosis and characterization of the disorder is esophagoduodenoscopy (EGD), high-resolution esophageal manometry, and symptom-associated ambulatory esophageal pH impedance monitoring...
June 16, 2017: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/28606718/abdominal-imaging-post-bariatric-surgery-predictors-usage-and-utility
#6
Dana Haddad, Aruna David, Haneen Abdel-Dayem, Nicholas Socci, Leaque Ahmed, Anthony Gilet
PURPOSE: A lack of well-defined postoperative imaging guidelines for bariatric patients may lead to false-positive findings, radiation exposure, additional cost, and patient anxiety. We investigated our institutional usage and utility of nonroutine postoperative abdominal imaging. METHODS AND MATERIALS: Laparoscopic gastric bypass and sleeve gastrectomy patients over a 5-year period were retrospectively identified. All bariatric-related nonroutine initial and all subsequent prompted abdominal and pelvic imaging was included...
April 29, 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/28604517/espghan-guidelines-for-the-evaluation-and-treatment-of-gastrointestinal-and-nutritional-complications-in-children-with-neurological-impairment
#7
Claudio Romano, Myriam van Wynckel, Jessie Hulst, Ilse Broekaert, Jiri Bronsky, Luigi Dall'Oglio, Nataša Fidler Mis, Iva Hojsak, Rok Orel, Alexandra Papadopoulou, Michela Schaeppi, Nikhil Thapar, Michael Wilschanski, Peter Sullivan, Frédéric Gottrand
OBJECTIVES: Feeding difficulties are frequent in children with neurological impairments and can be associated with undernutrition, growth failure, micronutrients deficiencies, osteopenia and nutritional comorbidites. Gastrointestinal problems including gastroesophageal reflux disease, constipation and dysphagia are also very frequent in this population and impact quality of life and nutritional status. There is currently a lack of a systematic approach to the care of these patients. With this report, ESPGHAN aims to develop uniform guidelines for the management of the gastroenterological and nutritional problems in neurologically impaired chidren...
June 9, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28600593/-paradoxical-sphincters-and-cardinal-continence-function-of-the-gastric-fundus
#8
F Stelzner, N Friedrichs
Gastroesophageal reflux disease is a common disorder in humans and has been treated for the last 67 years using fundoplication. However, treatment results have generally not been satisfactory. Physiological and anatomic findings must be taken into account to improve the therapy technique. In this article, these are described using the example of paradoxical sphincters and the effect of NO signal molecules in the gastrointestinal tract.
June 9, 2017: Der Chirurg; Zeitschrift Für Alle Gebiete der Operativen Medizen
https://www.readbyqxmd.com/read/28600380/cohort-profile-the-nordic-antireflux-surgery-cohort-nordasco
#9
John Maret-Ouda, Karl Wahlin, Miia Artama, Nele Brusselaers, Martti Färkkilä, Elsebeth Lynge, Fredrik Mattsson, Eero Pukkala, Pål Romundstad, Laufey Tryggvadóttir, My von Euler-Chelpin, Jesper Lagergren
PURPOSE: To describe a newly created all-Nordic cohort of patients with gastro-oesophageal reflux disease (GORD), entitled the Nordic Antireflux Surgery Cohort (NordASCo), which will be used to compare participants having undergone antireflux surgery with those who have not regarding risk of cancers, other diseases and mortality. PARTICIPANTS: Included were individuals with a GORD diagnosis recorded in any of the nationwide patient registries in the Nordic countries (Denmark, Finland, Iceland, Norway and Sweden) in 1964-2014 (with various start and end years in different countries)...
June 8, 2017: BMJ Open
https://www.readbyqxmd.com/read/28596098/acoustic-analysis-of-voice-and-electroglottography-in-patients-with-laryngopharyngeal-reflux
#10
Daphne Anahit Morales Ramírez, Víctor Manuel Valadez Jiménez, Xochiquetzal Hernández López, Pablo Antonio Ysunza
BACKGROUND: Laryngopharyngeal reflux (LPR) refers to the flow of gastric acid content into the laryngopharynx. It has been reported that 10% of the patients consulting an otolaryngologist present with this condition. Signs of LPR can be identified during flexible or rigid laryngoscopy. The Voice Handicap Index (VHI) is a reliable tool for detecting the impact of voice disorders, and acoustic assessment of voice including acoustic analysis of voice (AAV) and electroglottography (EGG) provide objective data of voice production and voice disorders...
June 5, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/28593484/reflux-sleeve-dilation-and-barrett-s-esophagus-after-laparoscopic-sleeve-gastrectomy-long-term-follow-up
#11
Daniel Moritz Felsenreich, Ronald Kefurt, Martin Schermann, Philipp Beckerhinn, Ivan Kristo, Michael Krebs, Gerhard Prager, Felix B Langer
BACKGROUND: Laparoscopic sleeve gastrectomy (SG) has become the most frequently performed bariatric procedure worldwide. De novo reflux might impact patients' quality of life, requiring lifelong proton pump inhibitor medication. It also increases the risk of esophagitis and formation of Barrett's metaplasia. Besides weight regain, gastroesophageal reflux disease (GERD) is the most common reason for conversion to Roux-en-Y gastric bypass. METHODS: We performed 24-h pH metries, manometries, gastroscopies, and questionnaires focusing on reflux (GIQLI, RSI) in SG patients with a follow-up of more than 10 years who did not suffer from symptomatic reflux or hiatal hernia preoperatively...
June 8, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28593183/columnar-metaplasia-in-three-types-of-surgical-mouse-models-of-esophageal-reflux
#12
Fabio Terabe, Susumu Aikou, Junko Aida, Nobutake Yamamichi, Michio Kaminishi, Kaiyo Takubo, Yasuyuki Seto, Sachiyo Nomura
BACKGROUND AND AIMS: Esophageal adenocarcinoma develops in the setting of gastroesophageal reflux and columnar metaplasia in distal esophagus. Columnar metaplasia arising in gastroesophageal reflux models has developed in rat; however, gastroesophageal reflux models in mice have not been well-characterized. METHODS: One hundred thirty-five C57Bl/6J mice aged 8 weeks old were divided into the following operations: esophagogastrojejunostomy (side-to-side) (EGJ), esophageal separation and esophagojejunostomy (end-to-side) (EJ), and EJ and gastrectomy (end-to-side) (EJ/TG)...
July 2017: Cellular and Molecular Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28591070/emerging-gastrointestinal-and-liver-diseases-in-asia-pacific-implications-to-health-care-in-the-region-world-gastroenterology-organization-asian-pacific-association-of-gastroenterology-distinguished-global-lecture-2015
#13
Khean-Lee Goh
Colorectal cancer (CRC), gastroesophageal reflux disease (GERD), inflammatory bowel disease (IBD), and nonalcoholic fatty liver disease are considered important emerging diseases in the Asia Pacific (AP) region. The incidence rate of CRC is the highest among gastrointestinal cancers in the region surpassing that of gastric cancer. However, population CRC screening is limited by availability of adequate health resources and financing. GERD is a highly prevalent disease in AP with the prevalence of GERD symptoms and reflux esophagitis reported to be increasing...
July 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/28584525/gastrointestinal-motility-disorders-and-their-clinical-implications-in-cirrhosis
#14
REVIEW
Eleni Theocharidou, Ameet Dhar, David Patch
Gastrointestinal motility is impaired in a substantial proportion of patients with cirrhosis. Cirrhosis-related autonomic neuropathy, increased nitric oxide production, and gut hormonal changes have been implicated. Oesophageal dysmotility has been associated with increased frequency of abnormal gastro-oesophageal reflux. Impaired gastric emptying and accommodation may result in early satiety and may have an impact on the nutritional status of these patients. Small intestinal dysmotility might be implicated in small intestinal bacterial overgrowth and increased bacterial translocation...
2017: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/28584403/increase-of-transient-lower-esophageal-sphincter-relaxation-associated-with-cascade-stomach
#15
Akiyo Kawada, Motoyasu Kusano, Hiroko Hosaka, Shiko Kuribayashi, Yasuyuki Shimoyama, Osamu Kawamura, Junichi Akiyama, Masanobu Yamada, Masako Akuzawa
We previously reported that cascade stomach was associated with reflux symptoms and esophagitis. Delayed gastric emptying has been believed to initiate transient lower esophageal sphincter relaxation (TLESR). We hypothesized that cascade stomach may be associated with frequent TLESR with delayed gastric emptying. Eleven subjects with cascade stomach and 11 subjects without cascade stomach were enrolled. Postprandial gastroesophageal manometry and gastric emptying using a continuous (13)C breath system were measured simultaneously after a liquid test meal...
May 2017: Journal of Clinical Biochemistry and Nutrition
https://www.readbyqxmd.com/read/28581835/development-and-gamma-scintigraphy-evaluation-of-gastro-retentive-calcium-ion-based-oral-formulation-an-innovative-approach-for-the-management-of-gastro-oesophageal-reflux-disease-gerd
#16
Braj Gaurav Sharma, Kushagra Khanna, Neeraj Kumar, Dhruv K Nishad, Mitra Basu, Aseem Bhatnagar
Calcium chloride is an essential calcium channel agonist which plays an important role in the contraction of muscles by triggering calcium channel. First time hypothesized about its role in the treatment of GER (gastro-oesophageal reflux) and vomiting disorder due to its local action. There are two objectives covered in the present study as first, the development & optimization of floating formulation of calcium chloride and another objective was to evaluated optimized formulation through gamma scintigraphy in human subjects...
June 5, 2017: Drug Development and Industrial Pharmacy
https://www.readbyqxmd.com/read/28576682/bile-reflux-of-the-remnant-stomach-following-roux-en-y-gastric-bypass-an-etiology-of-chronic-abdominal-pain-treated-with-remnant-gastrectomy
#17
Erika La Vella, Zach Hovorka, Donald E Yarbrough, Elizabeth McQuitty
BACKGROUND: Bile reflux gastritis of the remnant stomach following Roux-en-Y gastric bypass (RYGB) causing chronic abdominal pain has not been reported. We report a series of symptomatic patients with remnant gastritis treated effectively with remnant gastrectomy (RG). OBJECTIVE: The objective was to report our experience with bile reflux remnant gastritis after RYGB and our outcomes following RG. SETTING: Community teaching hospital. METHODS: All patients undergoing RG were retrospectively reviewed for presenting symptoms, diagnostic workup, pathology, complications, and symptom resolution...
April 15, 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/28569357/complications-following-the-mini-one-anastomosis-gastric-bypass-mgb-oagb-a-multi-institutional-survey-on-2678-patients-with-a-mid-term-5%C3%A2-years-follow-up
#18
Mario Musella, Antonio Susa, Emilio Manno, Maurizio De Luca, Francesco Greco, Marco Raffaelli, Stefano Cristiano, Marco Milone, Paolo Bianco, Antonio Vilardi, Ivana Damiano, Gianni Segato, Laura Pedretti, Piero Giustacchini, Domenico Fico, Gastone Veroux, Luigi Piazza
BACKGROUND: In recent years, several articles have reported considerable results with the Mini/One Anastomosis Gastric Bypass (MGB/OAGB) in terms of both weight loss and resolution of comorbidities. Despite those positive reports, some controversies still limit the widespread acceptance of this procedure. Therefore, a multicenter retrospective study, with the aim to investigate complications following this procedure, has been designed. PATIENTS AND METHODS: To report the complications rate following the MGB/OAGB and their management, and to assess the role of this approach in determining eventual complications related especially to the loop reconstruction, in the early and late postoperative periods, the clinical records of 2678 patients who underwent MGB/OAGB between 2006 and 2015 have been studied...
May 31, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28560291/gastrin-and-gastric-cancer
#19
REVIEW
Jill P Smith, Sandeep Nadella, Nick Osborne
Gastric cancer is the third leading cause of cancer-related mortality worldwide. Despite progress in understanding its development, challenges with treatment remain. Gastrin, a peptide hormone, is trophic for normal gastrointestinal epithelium. Gastrin also has been shown to play an important role in the stimulation of growth of several gastrointestinal cancers including gastric cancer. We sought to review the role of gastrin and its pathway in gastric cancer and its potential as a therapeutic target in the management of gastric cancer...
July 2017: Cellular and Molecular Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28549684/primary-laparoscopic-gastrojejunostomy-tubes-as-a-feeding-modality-in-the-pediatric-population
#20
Chinwendu Onwubiko, Brent R Weil, Sigrid Bairdain, Amber M Hall, Julia M Perkins, Hariharan Thangarajah, Maireade E McSweeney, C Jason Smithers
PURPOSE: Outcomes associated with primary laparoscopic gastrojejunal (GJ) tube placement in the pediatric population were evaluated. METHODS: A single-institution, retrospective review examined patients undergoing laparoscopic GJ tube placement between June 2011 and December 2014. Outcomes included gastric feeding tolerance, subsequent fundoplication, complications, and mortality. RESULTS: Ninety laparoscopic GJ tubes were placed. Median follow-up was 342days (interquartile range [IQR]=141-561days)...
May 20, 2017: Journal of Pediatric Surgery
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