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Gastric reflux

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https://www.readbyqxmd.com/read/28728310/the-effect-of-h2-receptor-antagonist-in-acid-inhibition-and-its-clinical-efficacy
#1
REVIEW
Young Kwang Shim, Nayoung Kim
The first histamine H2 receptor antagonists (H2RAs) were developed in the early 1970s. They played a dominant role in treating peptic ulcer disease and gastroesophageal reflux disease (GERD). H2RAs block the production of acid by H(+), K(+)-ATPase at the parietal cells and produce gastric luminal anacidity for varying periods. H2RAs are highly selective, and they do not affect H1 receptors. Moreover, they are not anticholinergic agents. Sequential development of H2RAs, proton pump inhibitors (PPIs), and discovery of Helicobacter pylori infection changed the paradigm of peptic ulcer disease with marked decrease of morbidity and mortality...
July 25, 2017: Korean Journal of Gastroenterology, Taehan Sohwagi Hakhoe Chi
https://www.readbyqxmd.com/read/28725999/surgical-anti-reflux-options-beyond-fundoplication
#2
REVIEW
Dan Azagury, John Morton
PURPOSE OF REVIEW: This paper provides an overview of current and future surgical interventions available for the management of gastroesophageal reflux disease (GERD) beyond the well established and recognized fundoplication. Review the current indications and outcomes of these surgical procedures. RECENT FINDINGS: Fundoplication has been a cornerstone of the surgical management of GERD. However, other effective surgical options exist and can be considered based on prior interventions as well as patient, anatomical or other factors...
July 2017: Current Gastroenterology Reports
https://www.readbyqxmd.com/read/28720085/my-child-cannot-breathe-while-sleeping-a-report-of-three-cases-and-review
#3
Won Hee Seo, Minkyu Park, So-Hee Eun, Seonkyeong Rhie, Dae Jin Song, Kyu-Young Chae
BACKGROUND: Sudden breath-holding episodes during sleep in young children are potentially related to sudden infant death syndrome and other life-threatening events. Additionally, these episodes can negatively affect child's growth and development. CASE PRESENTATION: Here, we present 3 cases of preschool children with similar paroxysmal nocturnal waking events associated with choking that had different etiologies (nocturnal frontal lobe epilepsy, nocturnal gastroesophageal reflux disease, and parasomnia, respectively)...
July 18, 2017: BMC Pediatrics
https://www.readbyqxmd.com/read/28717077/gastric-hyperplastic-polyps-associated-with-proton-pump-inhibitor-use-in-a-case-without-a-history-of-helicobacter-pylori-infection
#4
Shuichi Miyamoto, Mototsugu Kato, Kana Matsuda, Satoshi Abiko, Momoko Tsuda, Takeshi Mizushima, Keiko Yamamoto, Shoko Ono, Takahiko Kudo, Yuichi Shimizu, Kanako C Hatanaka, Izumi Tsunematsu, Naoya Sakamoto
A 56-year-old man with gastroesophageal reflux disease (GERD) was referred to our hospital. Esophagogastroduodenoscopy (EGD) revealed no evidence of any polypoid lesions in the stomach, and the patient had no history of Helicobacter pylori infection. He received omeprazole (20 mg) once daily for the GERD. EGD was performed at 1 year after the start of omeprazole administration, and this time, gastric hyperplastic polyps (GHPs) were detected. The GHPs increased in size as the omeprazole treatment continued, but they markedly decreased in size following omeprazole discontinuation...
2017: Internal Medicine
https://www.readbyqxmd.com/read/28707172/long-term-outcomes-of-laparoscopic-sleeve-gastrectomy-a-single-center-retrospective-study
#5
Piotr K Kowalewski, Robert Olszewski, Maciej S Walędziak, Michał R Janik, Andrzej Kwiatkowski, Natalia Gałązka-Świderek, Krzysztof Cichoń, Jakub Brągoszewski, Krzysztof Paśnik
INTRODUCTION: Sleeve gastrectomy (LSG) is one of the most popular bariatric procedures. We present our long-term results regarding weight loss, comorbidities, and gastric reflux disease. MATERIAL AND METHODS: We identified patients who underwent LSG in our institution between 2006 and 2009. We revised the data, and the patients with outdated contact details were tracked with the national health insurance database and social media (facebook). Each of the identified patients was asked to complete an online or telephone survey covering, among others, their weight and comorbidities...
July 13, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28707016/patterns-of-reoperation-after-failed-fundoplication-an-analysis-of-9462-patients
#6
Nabeel R Obeid, Maria S Altieri, Jie Yang, Jihye Park, Kristie Price, Andrew Bates, Aurora D Pryor
BACKGROUND: Little is known about the choice of reoperation after failed fundoplication for gastroesophageal reflux disease. Both redo fundoplication and conversion procedure to Roux-en-Y gastric bypass (RYGB) are safe and effective. We aimed to characterize the rates of different revisional procedures and to identify risk factors associated with failed fundoplication. METHODS: Using a statewide database, we examined records for patients who underwent fundoplication between 2000 and 2010...
July 13, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28702984/regenerative-medicine-in-the-treatment-of-gastro-esophageal-reflux-disease-and-laryngo-pharyngeal-reflux-from-research-to-cure
#7
S E Aragona, G Mereghetti, M Bianchetti, B Mangiavillano, T Zurlo, J Lotti, I La Mantia, K França, T Lotti
We present our observational study on 40 patients treated with the Hana medical device that releases magnesium alginate, performing a lubricating and hydrating action. This device is in the form of a gel, with topical action to contrast gastroesophageal reflux and to exert a mechanical role of protection of the mucosal tissues (mouth-pharyngo-esophageal mucosa and gastric mucose.). Forty patients were recruited aged between 22- and 72-years-old with painful dyspeptic Gastro Esophageal Reflux Disease (GERD) symptomatology in acute or in clinical phase (25 patients) and with pharyngo-laryngo-tracheal symptomatology (15 patients)...
July 13, 2017: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/28697146/gastric-reflux-into-the-gallbladder-after-eus-guided-stenting-letter-to-the-editor-regarding-eus-guided-versus-percutaneous-gallbladder-drainage-isn-t-it-time-to-convert
#8
Joseph J Kim, Spiros P Hiotis, Malini D Sur
No abstract text is available yet for this article.
July 10, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/28695879/iatrogenic-injury-of-the-intrathoracic-oesophagus-with-bougie-during-sleeve-gastrectomy
#9
Franco José Signorini, Gorodner Verónica, Marani Marcos, Viscido German, Moser Federico
One of the most popular procedures amongst obesity surgery is the sleeve gastrectomy. There is international consensus regarding the usage of bougie for sleeve gastrectomy calibration. Nevertheless, there is a dissociation between the number of oesophageal perforations reported for any other oesophageal/gastric operation that requires bougie (e.g., anti-reflux surgery, incidence 1.2%) and bariatric surgery, where this complication seems to be almost a myth. Interestingly enough, the number of bariatric procedures is much higher than any other oesophageal/gastric surgery...
July 7, 2017: Journal of Minimal Access Surgery
https://www.readbyqxmd.com/read/28690940/simultaneous-robot-assisted-laparoscopic-excision-of-pre-pyloric-gastrointestinal-stromal-tumor-and-cholecystectomy
#10
Ahsan Zil-E-Ali, Salman Assad, Furrukh Jabbar
Operating on more than a single procedure in a same surgical intervention saves time, anesthesia duration and can increase the overall quality of life by lowering the duration of hospital stay and minimizing patient anxiety. But such interventions require expertise, high surgical performance, and precision in anatomical manipulation. We present a case of an outstanding performance of a unique minimally invasive simultaneous approach of removing a pre-pyloric gastrointestinal stromal tumor (GIST) along with a cholecystectomy by a robot-assisted laparascopic surgical system...
June 3, 2017: Curēus
https://www.readbyqxmd.com/read/28672431/the-application-of-the-rome-iv-criteria-to-functional-esophagogastroduodenal-disorders-in-asia
#11
REVIEW
Hidekazu Suzuki
The Rome criteria were amended as Rome IV. For functional esophageal disorders, the exclusion criteria have been more specifically revised based on further understanding of other esophageal disorders, including eosinophilic esophagitis and spastic and hypercontractile motor disorders. Another revised point is the more restrictive definition of gastroesophageal reflux disease, indicating that sensitivity to a physiological reflux burden may be placed more firmly within the functional group. For functional dyspepsia (FD), only minor changes were introduced, mainly to improve specificity...
July 30, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28663533/conversion-to-endoscopic-ultrasound-guided-biliary-drainage-by-temporary-nasobiliary-drainage-placement-in-patients-with-prior-biliary-stenting
#12
Yousuke Nakai, Hiroyuki Isayama, Natsuyo Yamamoto, Saburo Matsubara, Yukiko Ito, Naoki Sasahira, Gyotane Umefune, Naminatsu Takahara, Tsuyoshi Hamada, Dai Mohri, Hirofumi Kogure, Minoru Tada, Kazuhiko Koike
BACKGROUND AND OBJECTIVES: Endoscopic ultrasound-guided biliary drainage (EUS-BD), first reported as an alternative to percutaneous transhepatic BD in failed endoscopic retrograde cholangiography, is sometimes performed as reintervention for transpapillary stent dysfunction such as in patients with new onset gastric outlet obstruction, but direct conversion to EUS-BD can potentially have a risk of leakage of infected bile. The aim of this study is to evaluate the safety and efficacy of conversion to EUS-BD using a temporary endoscopic nasobiliary drainage (ENBD) tube placement as a reintervention for prior BD...
February 8, 2017: Endoscopic Ultrasound
https://www.readbyqxmd.com/read/28662503/the-effects-of-switching-to-vonoprazan-a-novel-potassium-competitive-acid-blocker-on-gastric-acidity-and-reflux-patterns-in-patients-with-erosive-esophagitis-refractory-to-proton-pump-inhibitors
#13
Hiroshi Yamashita, Atsushi Kanamori, Chise Kano, Hiroki Hashimura, Kei Matsumoto, Masahiro Tsujimae, Tetsuya Yoshizaki, Kenji Momose, Daisuke Obata, Takaaki Eguchi, Mikio Fujita, Akihiko Okada
BACKGROUND/AIM: The effects of vonoprazan and proton pump inhibitors (PPIs) in patients with reflux esophagitis (RE) have not yet been compared using multichannel intraluminal impedance-pH (MII-pH). METHODS: A total of 8 patients with persistent gastric mucosal injury, despite completing an 8-week standard PPI therapy, were enrolled in the study. While they were on standard PPI therapy, the baseline values of reflux parameters, holding time ratio (HTR) of gastric pH >4, and esophageal pH <4 were obtained by using 24 h MII-pH monitoring...
June 30, 2017: Digestion
https://www.readbyqxmd.com/read/28660419/per-oral-endoscopic-myotomy-vs-laparoscopic-heller-myotomy-does-gastric-extension-length-matter
#14
Mauricio Ramirez, Cecilia Zubieta, Franco Ciotola, Alfredo Amenabar, Adolfo Badaloni, Fabio Nachman, Alejandro Nieponice
OBJECTIVE: To report our experience in POEM vs. LHM, with particular focus on myotomy extension. BACKGROUND: POEM has been adopted worldwide as a treatment for achalasia. While resolution of dysphagia is above 90%, postoperative reflux ranges from 10 to 57%. Myotomy length has been a controversial topic. METHODS: Thirty-five cases of POEM were prospectively analyzed and compared retrospectively to the last 35 patients that underwent LHM, from December 2010 to August 2016...
June 28, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28658159/outcomes-of-primary-gastric-transposition-for-long-gap-esophageal-atresia-in-neonates
#15
Zhandong Zeng, Fengli Liu, Juan Ma, Yun Fang, Hongwei Zhang
BACKGROUND: Gastric transposition is a relatively novel method of esophageal replacement. The purpose of this retrospective study was to assess the outcomes of long-gap esophageal atresia (LGEA) treated with esophageal replacement using primary gastric transposition in neonates. METHODS: Between March 2008 and May 2015, 14 newborns with LGEA were treated in our hospital. They were all found to have gaps of over 3 cm at the time of the surgery and were diagnosed with LGEA...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28657473/vonoprazan-fumarate-for-the-management-of-acid-related-diseases
#16
Irene Martinucci, Corrado Blandizzi, Giorgia Bodini, Elisa Marabotto, Vincenzo Savarino, Santino Marchi, Nicola de Bortoli, Edoardo Savarino
Proton pump inhibitors (PPIs) display a number of limitations and unmet clinical needs that have prompted the development of novel drugs to improve the outcomes of acid-related diseases, including the eradication of H. pylori. In this context, a new synthesized potassium-competitive acid blocker (P-CAB), vonoprazan, showed higher suppression of gastric acid secretion. Areas covered: This review discusses the current knowledge regarding the efficacy of vonoprazan in the treatment of acid-related diseases, with a particular focus on its use in Helicobacter pylori eradication...
August 2017: Expert Opinion on Pharmacotherapy
https://www.readbyqxmd.com/read/28652633/-enteral-nutrition-during-prone-positioning-in-mechanically-ventilated-patients
#17
Alberto Lucchini, Ilaria Bonetti, Gloria Borrelli, Nicola Calabrese, Sara Volpe, Roberto Gariboldi, Dario Minotti, Luigi Cannizzo, Stefano Elli, Roberto Fumagalli, Stefano Bambi
. Enteral nutrition during prone positioning in mechanically ventilated patients. INTRODUCTION: The Enteral Nutrition (EN) tends to be stopped during prone positioning to prevent the risk of acid reflux and vomiting. AIMS: To compare the gastric residual volume during continuous enteral nutrition in patients in prone and supine position. METHODS: Observational restrospective study on Acute Respiratory Distress Syndrome patients, mechanically ventilated, with continuous enteral nutrition implemented according to the same protocol, in prone and supine position...
April 2017: Assistenza Infermieristica e Ricerca: AIR
https://www.readbyqxmd.com/read/28638010/-evaluating-an-effectiveness-of-surgical-treatment-of-gastroesophageal-reflux-disease-combined-with-hiatal-hernia
#18
V V Mozharovskiy, A A Tsyganov, K V Mozharovskiy, A A Tarasov
AIM: To assess an effectiveness of surgical treatment of gastroesophageal reflux disease (GERD) combined with hiatal hernia (HH). MATERIAL AND METHODS: The trial included 96 patients with GERD and HH who were divided into 2 groups. The principal difference between groups was the use of surgery in the main group and therapeutic treatment in the comparison group. RESULTS: The effectiveness of surgical treatment is superior to therapeutic treatment of GERD by more than 2...
2017: Khirurgiia
https://www.readbyqxmd.com/read/28632697/increased-activity-in-the-lung-field-on-gastroesophageal-scintigraphy-is-not-always-due-to-aspiration
#19
Xiaofei Zhao, Hongming Zhuang
Elevated activity in the lung field on gastroesophageal scintigraphy (milk scan) generally indicates aspiration of the gastric content that has refluxed to the pharynx. An 18-year-old man underwent to gastroesophageal scintigraphy to assess the rate of gastric emptying. Increased activity was noted in the left lower lung field during the image acquisition. Careful analysis of the images showed that this activity was caused by hiatal herniation.
June 19, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28631878/gas-swallow-during-meals-in-patients-with-excessive-belching
#20
N Caballero, J Serra
BACKGROUND: Swallowed gas is an important source of abdominal gas, and aerophagia is often believed as a putative cause of gas-related abdominal symptoms. However, altered gas-swallow during meals has not been demonstrated. Our aim was to characterize the number of gas swallows during meals in patients complaining of excessive belching and gaseousness and a control group without abdominal symptoms during a 24-h period. METHODS: A 24-h pH-impedance monitoring was performed in 10 patients with excessive belching, and 11 patients without digestive symptoms or reflux in the pH-impedance study...
June 20, 2017: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
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