keyword
MENU ▼
Read by QxMD icon Read
search

ELS

keyword
https://www.readbyqxmd.com/read/29051729/negative-influence-of-motor-impairments-on-upper-limb-movement-patterns-in-children-with-unilateral-cerebral-palsy-a-statistical-parametric-mapping-study
#1
Cristina Simon-Martinez, Ellen Jaspers, Lisa Mailleux, Kaat Desloovere, Jos Vanrenterghem, Els Ortibus, Guy Molenaers, Hilde Feys, Katrijn Klingels
Upper limb three-dimensional movement analysis (UL-3DMA) offers a reliable and valid tool to evaluate movement patterns in children with unilateral cerebral palsy (uCP). However, it remains unknown to what extent the underlying motor impairments explain deviant movement patterns. Such understanding is key to develop efficient rehabilitation programs. Although UL-3DMA has been shown to be a useful tool to assess movement patterns, it results in a multitude of data, challenging the clinical interpretation and consequently its implementation...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/29045900/molecular-and-functional-characterization-of-lymphoid-progenitor-subsets-reveals-a-bipartite-architecture-of-human-lymphopoiesis
#2
Kutaiba Alhaj Hussen, Thien-Phong Vu Manh, Fabien Guimiot, Elisabeth Nelson, Emna Chabaane, Marc Delord, Maxime Barbier, Claire Berthault, Nicolas Dulphy, Antonio José Alberdi, Odile Burlen-Defranoux, Gerard Socié, Jean Christophe Bories, Jerôme Larghero, Valérie Vanneaux, Els Verhoeyen, Thierry Wirth, Marc Dalod, Jean Claude Gluckman, Ana Cumano, Bruno Canque
The classical model of hematopoiesis established in the mouse postulates that lymphoid cells originate from a founder population of common lymphoid progenitors. Here, using a modeling approach in humanized mice, we showed that human lymphoid development stemmed from distinct populations of CD127(-) and CD127(+) early lymphoid progenitors (ELPs). Combining molecular analyses with in vitro and in vivo functional assays, we demonstrated that CD127(-) and CD127(+) ELPs emerged independently from lympho-mono-dendritic progenitors, responded differently to Notch1 signals, underwent divergent modes of lineage restriction, and displayed both common and specific differentiation potentials...
October 17, 2017: Immunity
https://www.readbyqxmd.com/read/29043049/polyphagy-and-diversification-in-tussock-moths-support-for-the-oscillation-hypothesis-from-extreme-generalists
#3
Houshuai Wang, Jeremy D Holloway, Niklas Janz, Mariana P Braga, Niklas Wahlberg, Min Wang, Sören Nylin
Theory on plasticity driving speciation, as applied to insect-plant interactions (the oscillation hypothesis), predicts more species in clades with higher diversity of host use, all else being equal. Previous support comes mainly from specialized herbivores such as butterflies, and plasticity theory suggests that there may be an upper host range limit where host diversity no longer promotes diversification. The tussock moths (Erebidae: Lymantriinae) are known for extreme levels of polyphagy. We demonstrate that this system is also very different from butterflies in terms of phylogenetic signal for polyphagy and for use of specific host orders...
October 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/29038493/flexible-parental-care-uniparental-incubation-in-biparentally-incubating-shorebirds
#4
Martin Bulla, Hanna Prüter, Hana Vitnerová, Wim Tijsen, Martin Sládeček, José A Alves, Olivier Gilg, Bart Kempenaers
The relative investment of females and males into parental care might depend on the population's adult sex-ratio. For example, all else being equal, males should be the more caring sex if the sex-ratio is male biased. Whether such outcomes are evolutionary fixed (i.e. related to the species' typical sex-ratio) or whether they arise through flexible responses of individuals to the current population sex-ratio remains unclear. Nevertheless, a flexible response might be limited by the evolutionary history of the species, because one sex may have lost the ability to care or because a single parent cannot successfully raise the brood...
October 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29037523/a-systematic-review-of-measurement-properties-of-patient-reported-outcome-measures-in-psoriatic-arthritis-a-grappa-omeract-initiative
#5
REVIEW
Pil Højgaard, Louise Klokker, Ana-Maria Orbai, Kim Holmsted, Else M Bartels, Ying Ying Leung, Niti Goel, Maarten de Wit, Dafna D Gladman, Philip Mease, Lene Dreyer, Lars E Kristensen, Oliver FitzGerald, William Tillett, Laure Gossec, Philip Helliwell, Vibeke Strand, Alexis Ogdie, Caroline B Terwee, Robin Christensen
BACKGROUND: An updated psoriatic arthritis (PsA) core outcome set (COS) for randomized controlled trials (RCTs) was endorsed at the Outcome Measures in Rheumatology (OMERACT) meeting in 2016. OBJECTIVES: To synthesize the evidence on measurement properties of patient reported outcome measures (PROMs) for PsA and thereby contribute to development of a PsA core outcome measurement set (COMS) as described by the OMERACT Filter 2.0. METHODS: A systematic literature search was performed in EMBASE, MEDLINE and PsycINFO on Jan 1, 2017 to identify full-text articles with an aim of assessing the measurement properties of PROMs in PsA...
September 9, 2017: Seminars in Arthritis and Rheumatism
https://www.readbyqxmd.com/read/29037249/a-novel-self-micro-emulsifying-delivery-system-smeds-formulation-significantly-improves-the-fasting-absorption-of-epa-and-dha-from-a-single-dose-of-an-omega-3-ethyl-ester-concentrate
#6
Yan Qin, Hilde Nyheim, Else Marie Haram, Joseph M Moritz, Svein Olaf Hustvedt
BACKGROUND: Absorption of EPA and DHA from Omega-3-acid ethyl ester (EE) concentrate supplements occurs most efficiently when taken in context of a fatty meal; adequate fat intake is required to release bile salts that emulsify and pancreatic enzymes that digest omega-3-containing lipids in the intestine. Current guidelines recommend reduction in fat intake and therefore there is a need to optimize the absorption of Omega-3 in those consuming low-fat or no-fat meals. To this end, BASF has developed an Absorption Acceleration Technology, a novel self-micro-emulsifying delivery system (SMEDS) formulation of highly concentrated Omega-3-acid EE which enables rapid emulsification and microdroplet formation upon entering the aqueous environment of the gut therefore enhances the absorption...
October 16, 2017: Lipids in Health and Disease
https://www.readbyqxmd.com/read/29035759/the-beliefs-about-voices-questionnaire-revised-a-factor-structure-from-450-participants
#7
Clara Strauss, Kenneth Hugdahl, Flavie Waters, Mark Hayward, Josef J Bless, Liv E Falkenberg, Bodil Kråkvik, Arve Egil Asbjørnsen, Erik Johnsen, Igne Sinkeviciute, Rune A Kroken, Else-Marie Løberg, Neil Thomas
Hallucinated voices are common across psychiatric and non-clinical groups. The predominant cognitive theory about the impact of voices posits that beliefs about voice power ('Omnipotence') and voice intent ('Malevolence'/'Benevolence') play a key role in determining emotional and behavioral reactions. The revised Beliefs about Voices Questionnaire (BAVQ-R) was designed to assess these constructs, together with two styles of responding (Engagement and Resistance). The BAVQ-R is widely used in clinical and research settings, yet it has not received validation of its constructs and factor structure...
October 5, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/29035580/mutation-sensitivity-maps-identifying-residue-substitutions-that-impact-protein-structure-via-a-rigidity-analysis-in-silico-mutation-approach
#8
Michael Siderius, Filip Jagodzinski
Understanding how an amino acid substitution affects a protein's structure can aid in the design of pharmaceutical drugs that aim at countering diseases caused by protein mutants. Unfortunately, performing even a few amino acid substitutions in vitro is both time and cost prohibitive, whereas an exhaustive analysis that involves systematically mutating all amino acids in the physical protein is infeasible. Computational methods have been developed to predict the effects of mutations, but even many of them are computationally intensive or are else dependent on homology or experimental data that may not be available for the protein being studied...
October 16, 2017: Journal of Computational Biology: a Journal of Computational Molecular Cell Biology
https://www.readbyqxmd.com/read/29033874/testing-the-motor-simulation-account-of-source-errors-for-actions-in-recall
#9
Nicholas Lange, Timothy J Hollins, Patric Bach
Observing someone else perform an action can lead to false memories of self-performance - the observation inflation effect. One explanation is that action simulation via mirror neuron activation during action observation is responsible for observation inflation by enriching memories of observed actions with motor representations. In three experiments we investigated this account of source memory failures, using a novel paradigm that minimized influences of verbalization and prior object knowledge. Participants worked in pairs to take turns acting out geometric shapes and letters...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/29032025/characteristics-of-drinking-events-associated-with-heavy-episodic-drinking-among-adolescents-in-the-united-states
#10
Matthew E Rossheim, Caroline J Stephenson, Dennis L Thombs, Melvin D Livingston, Scott T Walters, Sumihiro Suzuki, Adam E Barry, Robert M Weiler
PURPOSE: To examine associations between characteristics of drinking events and the quantity of alcohol consumed by adolescents in the United States. METHODS: Analyses relied on 2011-2015 data from the National Survey on Drug Use and Health (NSDUH). The study sample included 8110 adolescents, ages 12-17years old, who drank alcohol in the past 30days. A logistic regression model, weighted for national estimation, was constructed to examine factors associated with heavy episodic drinking (HED; 5+ drinks for males, 4+ drinks for females) during the underage drinker's most recent drinking event...
October 10, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29029338/to-include-or-not-to-include-the-impact-of-gene-filtering-on-species-tree-estimation-methods
#11
Erin K Molloy, Tandy Warnow
With the increasing availability of whole genome data, many species trees are being constructed from hundreds to thousands of loci. Although concatenation analysis using maximum likelihood is a standard approach for estimating species trees, it does not account for gene tree heterogeneity, which can occur due to many biological processes, such as incomplete lineage sorting. Coalescent species tree estimation methods, many of which are statistically consistent in the presence of incomplete lineage sorting, include Bayesian methods that co-estimate the gene trees and the species tree, summary methods that compute the species tree by combining estimated gene trees, and site-based methods that infer the species tree from site patterns in the alignments of different loci...
September 15, 2017: Systematic Biology
https://www.readbyqxmd.com/read/29028233/ethics-in-public-health-call-for-shared-moral-public-health-literacy
#12
Els L M Maeckelberghe, Peter Schröder-Bäck
Public Health (PH) in Europe has become much more vocal about its moral understandings since 1992. The rising awareness that PH issues were inseparable from issues of human rights and social justice almost self-evidently directed the agenda of EUPHA and the European Public Health (EPH)-conferences. Problems of cultural and behavioural change, and environmental issues on a global scale were also added. The Section Ethics in PH invited the EPH community to join in 'arm chair thinking': coming together at conferences not only to share the 'how' and 'what' of PH research, practices and policies but also the 'why'...
October 1, 2017: European Journal of Public Health
https://www.readbyqxmd.com/read/29027313/patient-experiences-with-care-across-various-types-of-mental-health-care-questionnaire-development-measurement-invariance-and-patients-reports
#13
Luk Bruyneel, Sabine Van Houdt, Ellen Coeckelberghs, Walter Sermeus, Else Tambuyzer, Peter Cosemans, Gert Peeters, Kris Van den Broeck, Ilse Weeghmans, Kris Vanhaecht
To describe the development, validation, and findings of a patient experience questionnaire across 7 types of residential and ambulatory mental health care services. Thirty-five items were hypothesized to cover information, participation, therapeutic relationship, personalized care, organization and collaboration, safety, patient rights, outcomes of care, and discharge preparation and after-care. Also included were 2 overall rating items (scoring and recommending the organization). This Dutch questionnaire was applied in 79 organizations in Belgium (N patients = 5,168)...
October 13, 2017: International Journal of Methods in Psychiatric Research
https://www.readbyqxmd.com/read/29026601/complications-effectiveness-and-long-term-follow-up-of-fecal-microbiota-transfer-by-nasoduodenal-tube-for-treatment-of-recurrent-clostridium-difficile-infection
#14
Yvette H van Beurden, Pieter F de Groot, Els van Nood, Max Nieuwdorp, Josbert J Keller, Abraham Goorhuis
BACKGROUND: Fecal microbiota transfer (FMT) is an effective treatment for recurrent Clostridium difficile infection (CDI), but data on procedure-related complications and long-term outcome are scarce. METHODS: All patients treated with FMT for recurrent CDI at the Academic Medical Center between July 2010 and January 2016 were included. FMT was performed according to the FECAL trial protocol: administration of fresh donor feces (related or unrelated donor) through a duodenal tube after pre-treatment with vancomycin and bowel lavage...
October 2017: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/29025345/the-cosmetic-ingredient-review-program-expert-safety-assessments-of-cosmetic-ingredients-in-an-open-forum
#15
Ivan J Boyer, Wilma F Bergfeld, Bart Heldreth, Monice M Fiume, Lillian J Gill
The Cosmetic Ingredient Review (CIR) is a nonprofit program to assess the safety of ingredients in personal care products in an open, unbiased, and expert manner. Cosmetic Ingredient Review was established in 1976 by the Personal Care Products Council (PCPC), with the support of the US Food and Drug Administration (USFDA) and the Consumer Federation of America (CFA). Cosmetic Ingredient Review remains the only scientific program in the world committed to the systematic, independent review of cosmetic ingredient safety in a public forum...
September 2017: International Journal of Toxicology
https://www.readbyqxmd.com/read/29024188/the-impact-of-sleep-deprivation-on-visual-perspective-taking
#16
Gaétane Deliens, Henryk Bukowski, Hichem Slama, Andrew Surtees, Axel Cleeremans, Dana Samson, Philippe Peigneux
Total sleep deprivation (TSD) is known to alter cognitive processes. Surprisingly little attention has been paid to its impact on social cognition. Here, we investigated whether TSD alters levels-1 and -2 visual perspective-taking abilities, i.e. the capacity to infer (a) what can be seen and (b) how it is seen from another person's visual perspective, respectively. Participants completed levels-1 and -2 visual perspective-taking tasks after a night of sleep and after a night of TSD. In these tasks, participants had to take their own (self trials) or someone else's (other trials) visual perspective in trials where both perspectives were either the same (consistent trials) or different (inconsistent trials)...
October 11, 2017: Journal of Sleep Research
https://www.readbyqxmd.com/read/29020619/remarkable-stability-of-myelinating-oligodendrocytes-in-mice
#17
Richa B Tripathi, Martyna Jackiewicz, Ian A McKenzie, Eleni Kougioumtzidou, Matthew Grist, William D Richardson
New myelin-forming oligodendrocytes (OLs) are generated in the mouse central nervous system during adulthood. These adult-born OLs might augment the existing population, contributing to neural plasticity, or else replace OLs that die in use (turnover). To distinguish between these alternatives, we induced genetic labeling of mature myelinating OLs in young adult mice and tracked their subsequent survival. OL survival rates were region dependent, being higher in corpus callosum (∼90% survival over 20 months) and motor cortex (∼70% survival) than in corticospinal tract or optic nerve (50%-60% survival)...
October 10, 2017: Cell Reports
https://www.readbyqxmd.com/read/29020011/a-microfluidic-renal-proximal-tubule-with-active-reabsorptive-function
#18
Else M Vedula, José Luis Alonso, M Amin Arnaout, Joseph L Charest
In the kidney, the renal proximal tubule (PT) reabsorbs solutes into the peritubular capillaries through active transport. Here, we replicate this reabsorptive function in vitro by engineering a microfluidic PT. The microfluidic PT architecture comprises a porous membrane with user-defined submicron surface topography separating two microchannels representing a PT filtrate lumen and a peritubular capillary lumen. Human PT epithelial cells and microvascular endothelial cells in respective microchannels created a PT-like reabsorptive barrier...
2017: PloS One
https://www.readbyqxmd.com/read/29019799/to-see-the-suffering
#19
Rita Charon
The author notes the impressive growth in medical humanities programs, scholarly journals, textbooks, and national and international conferences as well as the convening of two recent national forums or boards addressing the potential of the humanities and the arts to improve medical practice. She also notes that the field of medical humanities seems to have shifted from addressing topics on the margins of medical education to equipping students with the foundational skills required for effective doctoring...
October 10, 2017: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/28994253/addiction-medicine-ethics-relapse-no-lapse-and-the-struggle-to-treat-addicts-like-everyone-else
#20
Charles Douglas
Two case studies are presented as a focus for discussion of ethics in addiction medicine. The first is that of the alcohol-dependent patient who receives a liver transplant. The second is that of a heroin-dependent patient who continues to inject himself while in a general medical ward. I make some comments about the obligations of doctors to treat those who cause harm to themselves as they would treat those who are 'not responsible'.
October 2017: Internal Medicine Journal
keyword
keyword
84051
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"