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post-stroke spasticity

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https://www.readbyqxmd.com/read/28211822/robot-assisted-end-effector-based-gait-training-in-chronic-stroke-patients-a%C3%A2-multicentric-uncontrolled-observational-retrospective-clinical-study
#1
Stefano Mazzoleni, Antonella Focacci, Marco Franceschini, Andreas Waldner, Chiara Spagnuolo, Elena Battini, Donatella Bonaiuti
BACKGROUND: Until now studies report inconclusive results as regards the effectiveness of exclusive use of robot-assisted training and clinical indications in stroke patients. OBJECTIVE: To evaluate if the only robot-assisted end-effector-based gait training can be feasible in chronic stroke subjects in terms of gait recovery. METHODS: Five rehabilitation centers participated and one hundred chronic post-stroke patients were recruited. Patients underwent a robot-assisted end-effector-based gait training as only rehabilitation treatment...
February 15, 2017: NeuroRehabilitation
https://www.readbyqxmd.com/read/28145396/a-randomized-controlled-trial-on-the-immediate-and-long-term-effects-of-arm-slings-on-shoulder-subluxation-in-stroke-patients
#2
Anke VAN Bladel, Gert Lambrecht, Kristine M Oostra, Guy Vanderstraeten, Dirk Cambier
BACKGROUND: Arm slings are often used in clinical practice to support the hemiplegic arm aiming to prevent or treat glenohumeral subluxation. Evidence supporting the corrective effect of slings on subluxation is scarce and long-term studies are lacking. AIM: To determine both the immediate and long-term effect on acromiohumeral distance using the Actimove® sling (BSN medical SA-NV, Leuven, Belgium) and Shoulderlift (V!GO, Belgium) and to determine the effect of slings on pain and passive range of motion of the shoulder in stroke patients with glenohumeral subluxation...
January 30, 2017: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/28131185/combined-therapy-using-botulinum-toxin-a-and-single-joint-hybrid-assistive-limb-for-upper-limb-disability-due-to-spastic-hemiplegia
#3
Kazuya Saita, Takashi Morishita, Koichi Hyakutake, Hiroyuki Fukuda, Etsuji Shiota, Yoshiyuki Sankai, Tooru Inoue
We investigated the combination of robot-assisted rehabilitation (RT) using a single-joint hybrid assistive limb (HAL-SJ) and botulinum toxin A (BTX-A) as therapy for paretic arm with spasticity in post-stroke patients. Participants were seven patients (4 females, 3 males; mean (±SD) age: 60.6±8.4years) who had spastic hemiplegia following chronic stroke. On the day following BTX-A injection, we started RT, which was performed for 20 sessions of 60min each over a two-week period. Clinical outcome measures, including Fugl-Meyer Assessment (FMA), Motor Activity Log (MAL), and Disability Assessment Scale (DAS), and cortical activity were evaluated at baseline, and two weeks, and four months following BTX-A injection...
February 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28118733/safety-and-efficacy-of-letibotulinumtoxina-botulax%C3%A2-in-treatment-of-post-stroke-upper-limb-spasticity-a-randomized-double-blind-multi-center-phase-iii-clinical-trial
#4
Kyung Hee Do, Min Ho Chun, Nam-Jong Paik, Yoon Ghil Park, Shi-Uk Lee, Min-Wook Kim, Don-Kyu Kim
OBJECTIVE: To investigate a new botulinum neurotoxin type A, termed letibotulinumtoxinA(Botulax(®)) and compare its efficacy and safety for post-stroke upper limb spasticity with that of onabotulinumtoxinA(Botox(®)). DESIGN: A prospective, double-blinded, multicenter, randomized controlled clinical study. SETTING: Six university hospitals in Korea. SUBJECTS: A total of 187 stroke participants with upper limb spasticity...
January 1, 2017: Clinical Rehabilitation
https://www.readbyqxmd.com/read/28071962/the-feasibility-of-functional-electrical-stimulation-to-improve-upper-extremity-function-in-a-two-year-old-child-with-perinatal-stroke-a-case-report
#5
Kristin E Musselman, Patricia Manns, Jaclyn Dawe, Rhina Delgado, Jaynie F Yang
AIMS: To evaluate the effectiveness and feasibility (i.e. tolerability, adherence) of functional electrical stimulation (FES) for the upper extremity (UE) in a two-year-old child with perinatal stroke. METHODS: Forty hours of FES over eight weeks was prescribed. FES to the hemiplegic triceps, extensor carpi radialis longus and brevis, extensor carpi ulnaris and extensor digitorum was timed with reaching during play. Assessments were performed before, during, and two months post-intervention...
January 10, 2017: Physical & Occupational Therapy in Pediatrics
https://www.readbyqxmd.com/read/27940322/an-improved-approach-for-measuring-the-tonic-stretch-reflex-response-of-spastic-muscles
#6
Maristella Borges Silva, Andrei Nakagawa Silva, Eduardo Lázaro Martins Naves, Evanisi Teresa Palomari, Alcimar Barbosa Soares
We propose a new method for detecting the onset of the stretch reflex response for assessment of spasticity based on the Tonic Stretch Reflex Threshold (TSRT). Our strategy relies on a three-stage approach to detect the onset of the reflex EMG activity: (i) Reduction of baseline activity by means of Empirical Mode Decomposition; (ii) Extraction of the complex envelope of the EMG signal by means of Hilbert Transform (HT) and; iii) A double threshold decision rule. Simulated and real EMG data were used to evaluate and compare our method (TSRT-EHD) against three other popular methods described in the literature to assess TSRT ('Kim', 'Ferreira' and 'Blanchette')...
December 2, 2016: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/27880052/functional-impact-of-different-muscle-localization-techniques-for-botulinum-neurotoxin-a-injections-in-clinical-routine-management-of-post-stroke-spasticity
#7
Kirsten E Zeuner, Arne Knutzen, Carina Kühl, Bettina Möller, Helge Hellriegel, Nils G Margraf, Günther Deuschl, Henning Stolze
BACKGROUND: Treatment options for spasticity include intramuscular botulinum neurotoxin A (BoNT-A) injections. Both ultrasound (US) or electromyographic (EMG) guided BoNT-A injections are employed to isolate muscles. To date, most studies have included patients naïve to BoNT-A or following a prolonged wash out phase. OBJECTIVE: To determine the impact of US/EMG guided BoNT-A injections on function in outpatients with spasticity receiving an established re-injection regime...
2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/27879456/hindlimb-spasticity-after-unilateral-motor-cortex-lesion-in-rats-is-reduced-by-contralateral-nerve-root-transfer
#8
Haiyang Zong, Fenfen Ma, Laiyin Zhang, Huiping Lu, Jingru Gong, Min Cai, Haodong Lin, Yizhun Zhu, Chunlin Hou
Lower extremity spasticity is a common sequela among patients with acquired brain injury. The optimum treatment remains controversial. The aim of our study was to test the feasibility and effectiveness of contralateral nerve root transfer in reducing post stroke spasticity of the affected hindlimb muscles in rats. In our study, we for the first time created a novel animal hindlimb spastic hemiplegia model in rats with photothrombotic lesion of unilateral motor cortex and we established a novel surgical procedure in reducing motor cortex lesion-induced hindlimb spastic hemiplegia in rats...
December 2016: Bioscience Reports
https://www.readbyqxmd.com/read/27871449/botulinum-toxin-as-early-intervention-for-spasticity-after-stroke-or-non-progressive-brain-lesion-a-meta-analysis
#9
Raymond L Rosales, Fran Efendy, Ericka Sa Teleg, Mary Md Delos Santos, Mary Ce Rosales, Marc Ostrea, Michelle J Tanglao, Arlene R Ng
Spasticity is a functionally limiting disorder that commonly occurs following stroke or severe brain injury, and may lead to disability and pain. In tandem with neurorehabilitation, botulinum toxin type A (BoNT-A) is the recommended first-line treatment for spasticity and, to date, the majority of trials have reported BoNT-A use in patients >6months after ictus. The present meta-analysis aimed to evaluate the effects of early BoNT-A injection for post-stroke spasticity on improvements in hypertonicity, disability, function and associated pain...
December 15, 2016: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/27834471/efficacy-and-safety-of-botulinum-toxin-type-a-for-upper-limb-spasticity-after-stroke-or-traumatic-brain-injury-a-systematic-review-with-meta-analysis-and-trial-sequential-analysis
#10
Yan Dong, Tao Wu, Xiaohua Hu, Tong Wang
INTRODUCTION: Muscle spasticity is a positive symptom after stroke and traumatic brain injury. Botulinum Toxin type A injection is widely used for treating post stroke and traumatic brain injury spasticity. This study aimed to evaluate efficacy and safety of Botulinum Toxin type A for upper limb spasticity after stroke and traumatic brain injury and investigate reliability and conclusiveness of available evidence for Botulinum Toxin type A intervention. EVIDENCE ACQUISITION: We searched electronic databases from inception to September 10 of 2016...
November 11, 2016: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27824235/radial-shock-wave-therapy-effect-on-pain-and-motor-performance-in-a-paralympic-athlete-a-case-report
#11
Laura Mori, Lucio Marinelli, Elisa Pelosin, Matteo Gambaro, Roberto Trentini, Giovanni Abbruzzese, Carlo Trompetto
BACKGROUND: Recent studies demonstrated the usefulness of Radial Shock Waves Therapy (RSWT) in treating hypertonia in patients affected by cerebral palsy (CP), stroke, and dystonia. RSWT have never been used to treat spasticity in disabled athletes. CASE REPORT: An athlete affected by tetraparesis due to CP underwent three RSWT sessions in a week. We assessed muscular tone using the Modified Ashworth scale (MAS), pain and fatigue experienced during athletic performance with Visual Analogic Scale (VAS) and Borg scale Category-Ratio anchored at number 10 (Borg CR10)...
November 8, 2016: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27814307/effect-of-shock-wave-therapy-on-ankle-planter-flexors-spasticity-in-stroke-patients
#12
Salah Sawan, Foad Abd-Allah, Montasser M Hegazy, Mohammad A Farrag, Nancy Hosney Sharf El-Den
BACKGROUND: Large number of patients with first-ever stroke developed spasticity. Spasticity can reduce the range of motion, hinder voluntary movements, provoke pain, and result in impairment of functional activities of daily living. OBJECTIVE: Demonstrate the effect of shock wave therapy on ankle planter flexors spasticity in stroke patients. METHODS: We included forty ischemic stroke patients divided into 2 groups; group I were subjected to the selected physical therapy program and shock wave therapy whereas group II received the selected physical therapy program as well as placebo shock wave for six weeks...
October 31, 2016: NeuroRehabilitation
https://www.readbyqxmd.com/read/27699753/-early-pharmacologic-treatment-with-botulinum-toxin-a-in-post-stroke-spasticity-consensus-evidence-based-recommendations
#13
REVIEW
L Lopez de Munain, F J Juan-Garcia, E Duarte, R Martin-Mourelle, S Rodriguez, S Moraleda-Perez
Spasticity is a common complication that occurs in those patients that have suffered a stroke. To identify those patients at high risk of having post-stroke spasticity and to start treatment at early stages would probably benefit the patient. The key aspects in the early management of post-stroke spasticity were review and the clinical implications and strength of evidences were also considered. The document drafted by the study coordinators was subsequently reviewed and then a validated document was developed...
October 16, 2016: Revista de Neurologia
https://www.readbyqxmd.com/read/27696580/goal-attainment-scaling-in-individuals-with-upper-limb-spasticity-post-stroke
#14
Parvin Eftekhar, George Mochizuki, Tilak Dutta, Denyse Richardson, Dina Brooks
Focusing on rehabilitation goals is an effective approach for improving function in individuals with spasticity after stroke. The objectives of this study were to examine and map goals of post-stroke individuals with spasticity using the Goal Attainment Scale (GAS) and International Classification of Functioning, Disability and Health (ICF), and to evaluate the impact of botulinum toxin A (BoNTA) on occupational performance based on the type of rehabilitation goals. Thirty-one patients were recruited from an outpatient spasticity management clinic...
December 2016: Occupational Therapy International
https://www.readbyqxmd.com/read/27679870/assessment-of-forearm-muscle-spasticity-with-sonoelastography-in-patients-with-stroke
#15
Evren Yaşar, Emre Adigüzel, Serdar Kesikburun, Itır Yenihayat, Bilge Yilmaz, Rıdvan Alaca, Arif K Tan
OBJECTIVE: The aim of the study was to investigate the feasibility of sonoelastography to show muscle stiffness in post-stroke spasticity, and the relationship between sonoelastography findings and clinical spasticity scores in the spastic forearm muscles. METHODS: This study was carried out in a university rehabilitation centre. 23 patients with stroke with forearm muscle spasticity (≥1+ using the Modified Ashworth scale score and ≥1 using the Tardieu scale) were included...
December 2016: British Journal of Radiology
https://www.readbyqxmd.com/read/27677008/structural-and-physiological-muscle-changes-after-post-stroke-hemiplegia-a-systematic-review
#16
Oscar Aze, Étienne Odjardias, Xavier Devillard, Barnabé Akplogan, Paul Calmels, Pascal Giraux
OBJECTIVE: Corticospinal tract damage is responsible for motor function impairment after stroke. However, many processes seem to induce muscle damage, which may limit rehabilitation achievement. To achieve a systematic literature review of human muscular modifications due to post-strike hemiplegia. This review considers structural (histological, biochemical) and physiological modifications and their functional consequences over 1 year after stroke. MATERIAL/PATIENTS AND METHODS: Literature search on PubMed, Embase and Cochrane databases for papers published before February 2016 combining the following keywords cerebral stroke, hemiplegic, atrophy, muscle structure, paresis, skeletal muscle fiber type, motor unit, oxidative stress, strength, motor control led to select forty articles...
September 2016: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27676991/isokinetic-muscular-strengthening-of-upper-limb-versus-passive-movement-in-chronic-stroke-patients-randomised-controlled-trial
#17
Flavia Coroian, Jérôme Froger, H-Y Bonnin Koang, Claire Jourdan, Karima Bakhti, Marc Julia, Audrey Jaussent, Christian Hérisson, Isabelle Laffont
OBJECTIVE: The sensori-motor impairment of upper limb (UL) affects more than 50% of patients after stroke. The objective of this work was to study the efficiency of isokinetic muscle strengthening (IMS) in the chronic phase of stroke in this population. MATERIAL/PATIENTS AND METHODS: The patients underwent 6 weeks of outpatient rehabilitation, 3 days per week, combining physiotherapy (twice/day) and occupational therapy every day. The program was completed by 30 minutes elbow and wrist concentric slow speed IMS of flexor and extensor muscles, in the study group versus 30 minutes passive mobilisation of the joints carried out by the same isokinetic dynamometer in the control group...
September 2016: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27676845/prevalence-and-functional-impact-of-self-reported-joint-stiffness-after-stroke-results-of-a-french-national-disability-health-survey
#18
Alexis Schnitzler, François Genêt, Claire Jourdan, Loic Josserand, Philippe Azouvi
OBJECTIVE: The prevalence of joint stiffness following stroke is not known. Post-stroke spasticity is considered to be an important contributing factor to disability. MATERIALS/PATIENTS AND METHODS: To evaluate the prevalence of joint stiffness in persons with a history of stroke in the whole French population, and the impact of joint stiffness on function. METHODS: The "Disability Health" survey was carried out in people's homes (DHH) and in institutions (DHI) in France...
September 2016: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27676800/plastic-changes-in-spinal-synaptic-transmission-following-botulinum-toxin-a-in-post-stroke-spastic-patients
#19
Marjorie Kerzoncuf, Laurent Bensoussan, Jean Michel Viton, Alain Delarque, Christiane Rossi Durand
OBJECTIVE: The therapeutic effects of intramuscular injections of botulinum toxin-type A on spasticity can be largely explained by its blocking action at the neuromuscular junction. BTx-A is assumed also to have a central action by affecting the functional organization of the CNS. The objective was to assess its action on spinal motor networks by investigating the post-activation depression (post-AD) of the soleus H-reflex in post-stroke patients. Post-AD that is a presynaptic mechanism controlling the synaptic efficacy of Ia-motoneuron transmission is involved in the pathophysiology of spasticity...
September 2016: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27676203/comparison-of-exercise-training-effect-with-different-robotic-devices-for-upper-limb-rehabilitation-a-retrospective-study
#20
Roberto Colombo, Fabrizio Pisano, Carmen Delconte, Alessandra Mazzone, Giuseppe Grioni, Marisa Castagna, Giacomo Bazzini, Chiara Imarisio, Giorgio Maggioni, Caterina Pistarini
BACKGROUND: Several robotic devices have been proposed for upper limb rehabilitation, but they differ in terms of application fields and the technical solutions implemented. AIM: To compare the effectiveness of three different robotic devices for shoulder-elbow rehabilitation in reducing motor impairment and improving motor performance in post-stroke patients. DESIGN: Retrospective multi-center study. SETTING: Inpatient rehabilitation hospital...
September 27, 2016: European Journal of Physical and Rehabilitation Medicine
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