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Hair transplant

Suruchi Garg
CONTEXT: Platelet-rich plasma (PRP) therapy is finding importance in aesthetic medicine. AIM: The objective of this study was to study efficacy of PRP therapy in follicular unit extraction (FUE) hair transplant. MATERIALS AND METHODS: It is a single-blind, prospective randomised study on 40 FUE hair transplant subjects, allocated in two groups (PRP and non-PRP) alternately. PRP was injected intra-operatively immediately after creating slits over the recipient area in PRP group; and normal saline in non-PRP group...
July 2016: Journal of Cutaneous and Aesthetic Surgery
Sanusi Umar
: Hair transplantation involving patients with tightly curled Afro-textured hair using follicular unit extraction (FUE) employing conventional rotary punches frequently leads to unacceptably high transection rates. These patients are unsuitable candidates for FUE hair transplantation. Transection rates were observed during FUE in a case series of 18 patients with tightly curled Afro-textured hair using different punches. METHODS: Three different punches were sequentially used in patients to extract follicular units with several needle gauges until satisfactory transection rates occurred: conventional sharp and dull rotary punches, followed by a 2-pronged curved nonrotary punch...
September 2016: Plastic and Reconstructive Surgery. Global Open
Bowen Gao, Qingxiong Yu, Feng Xie, Lingling Sheng, Xiyuan Mao, Qingfeng Li, Hainan Zhu
BACKGROUND: Conventional reconstructive methods fail to achieve satisfactory results in total eyelid defect cases. Vascularized composite tissue allotransplantation might provide both good appearance and function for these patients. The structure of the eyelid is exceptional because it simultaneously consists of skin, connective tissue, the striated muscle, fiber structure, aponeuroses, and mucosa. Thus, before clinical application of eyelid allotransplantation, more experiments are needed to clarify the impact of ischemia, immunal suppressive agents, and deinnervation effects on these sophisticated structures...
October 13, 2016: Ophthalmic Plastic and Reconstructive Surgery
María-Luisa Martínez, Eduardo Escario, Enrique Poblet, David Sánchez, Fernando-Francisco Buchón, Ander Izeta, Francisco Jimenez
BACKGROUND: A prominent role of hair follicle-derived cells in epidermal wound closure is now well established but clinical translation of basic research findings is scarce. Although skin punch grafts have been used as a therapeutic intervention to improve healing of chronic leg ulcers, they are normally harvested from nonhairy areas, thus not taking advantage of the reported role of the hair follicle as a wound-healing promoter. OBJECTIVE: We sought to substantiate the role of hair follicles in venous leg ulcer healing by transplanting hair follicle-containing versus nonhairy punch grafts...
November 2016: Journal of the American Academy of Dermatology
Jin Yong Kim, Ji-Seon Yoon, Bo Mi Kang, Hyein Yum, Hi-Jung Park, Doo-Wan Cho, Young-Su Yang, Su-Cheol Han, Wooseok Koh, Jae-Il Lee, Kyeong Cheon Jung, Kyu Han Kim, Ohsang Kwon
No abstract text is available yet for this article.
October 7, 2016: Journal of Investigative Dermatology
K Eustace, V Jolliffe, A Sahota, K Gholam
A 28-year-old man presented with a 10-day history of scalp nodules. He had undergone hair transplantation 2 months previously. Incision and drainage of one of the nodules yielded gelatinous material, which was sent for microscopy and culture, including low-temperature culture. After 2 weeks of incubation, culture of the nodule yielded acid- and alcohol-fast bacilli, which were identified as Mycobacterium abscessus, a rapidly growing, nontuberculous mycobacterium, which has been reported to cause cutaneous, soft tissue and respiratory infections following trauma, surgery or injection with nonsterile needles...
October 2016: Clinical and Experimental Dermatology
Ali Abbasi, Kambiz Kamyab-Hesari, Ramin Rabbani, Farzaneh Mollaee, Sheida Abbasi
BACKGROUND: Lichen planopilaris (LPP) is a follicular variant of lichen planus. A new subtype of LPP mimicking androgenetic alopecia (AGA) may be misdiagnosed. Inappropriate medical therapy or hair transplantation may exacerbate this subtype. OBJECTIVE: To introduce clinicopathologic findings of a new subtype of LPP that selectively affects vellus hair in the pattern of AGA. MATERIALS AND METHODS: In a cross-sectional study, 433 (66.6%) men and 217 (33...
October 2016: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
Agnes Rosarina Prita Sari, Nicholas Wolfgang Rufaut, Leslie Norman Jones, Rodney Daniel Sinclair
CONTEXT: In androgenetic alopecia, follicular miniaturization and dynamic changes to the hair cycle produce patterned baldness. The most effective treatment for baldness is hair transplantation surgery. The major limitation to hair transplantation is the availability of donor hair from the relatively unaffected occipital scalp. Hair induction with in vitro expansion of donor follicle populations has the potential to overcome this. The major obstacle to this is that in vitro expansion of human dermal papilla cell (DPC) colonies is associated with irreversible loss of aggregative behavior and hair follicle-inductive potential...
July 2016: International Journal of Trichology
Natacha A Agabalyan, Breanna S Borys, Holly D Sparks, Kathryn Boon, Eko W Raharjo, Sepideh Abbasi, Michael S Kallos, Jeff Biernaskie
: : Endogenous dermal stem cells (DSCs) reside in the adult hair follicle mesenchyme and can be isolated and grown in vitro as self-renewing colonies called skin-derived precursors (SKPs). Following transplantation into skin, SKPs can generate new dermis and reconstitute the dermal papilla and connective tissue sheath, suggesting they could have important therapeutic value for the treatment of skin disease (alopecia) or injury. Controlled cell culture processes must be developed to efficiently and safely generate sufficient stem cell numbers for clinical use...
September 9, 2016: Stem Cells Translational Medicine
Amir Feily, Ahmad Feily
Serious complications arising from surgical hair restoration are relatively uncommon following well-performed and well-planned surgery by skillful surgical techniques, good communication, and postoperative follow-up. Surgical complications often categorized as those which occur in the donor site and the recipient site. In this paper among recipient area complication we focused on recipient area necrosis that arises when an increased number of recipient grafts are utilized and de-vascularization of the scalp occurs as a result of the large wound area due to the dense packing splitting of recipient skin...
September 9, 2016: Dermatologic Therapy
Shruti Mohankumar Menon, Yugal K Sharma, Prakhar Bansal, Shruti S Ghadgepatil
Vitiligo is an acquired, idiopathic depigmentary disease resisting satisfactory repigmentation despite multimodal therapy. Based on the concept of activation of the existing undifferentiated stem cells in the outer root sheet of the hair follicles, follicular unit extraction (FUE) transplant is an interesting advancement in the field of minimally invasive surgery for vitiligo. We herein present three cases of vitiligo whose residual recalcitrant foci as well as poliosis - refractory to therapy including with previous nonculture melanocyte-keratinocyte transplant - repigmented satisfactorily after FUE transplant...
April 2016: International Journal of Trichology
Aarti N Shah, Ritu K Marfatia, Siddhartha S Saikia
CONTEXT: Vitiligo surgeries have come a long way from tissue grafts to cultured and non cultured cell transplantation. Extracted hair follicle outer root sheath cell transplantation (EHF ORS) suspension is more enriched with melanocyte. In a hair bulb, there is one melanocyte for every five keratinocytes which is much higher than the epidermal melanin unit. AIMS: To analyse the effectiveness of cultured EHF ORS and to perform objective evaluation based on clinical improvement & photographic evidence...
April 2016: International Journal of Trichology
Hainan Lang, Eishi Nishimoto, Yazhi Xing, LaShardai N Brown, Kenyaria V Noble, Jeremy L Barth, Amanda C LaRue, Kiyoshi Ando, Bradley A Schulte
The peripheral auditory nerve (AN) carries sound information from sensory hair cells to the brain. The present study investigated the contribution of mouse and human hematopoietic stem cells (HSCs) to cellular diversity in the AN following the destruction of neuron cell bodies, also known as spiral ganglion neurons (SGNs). Exposure of the adult mouse cochlea to ouabain selectively killed type I SGNs and disrupted the blood-labyrinth barrier. This procedure also resulted in the upregulation of genes associated with hematopoietic cell homing and differentiation, and provided an environment conducive to the tissue engraftment of circulating stem/progenitor cells into the AN...
October 4, 2016: Molecular Therapy: the Journal of the American Society of Gene Therapy
Wu Minjuan, Xiong Jun, Shao Shiyun, Xu Sha, Ni Haitao, Wang Yue, Ji Kaihong
Early repair of skin injury and maximal restoration of the function and appearance have become important targets of clinical treatment. In the present study, we observed the healing process of skin defects in nude mice and structural characteristics of the new skin after transplantation of isolated and cultured adipose derived mesenchymal stem cells (ADMSCs) onto the human acellular amniotic membrane (AAM). The result showed that ADMSCs were closely attached to the surface of AAM and grew well 24 h after seeding...
2016: Stem Cells International
Amir Feily, Vahid Seifi, Marigdalia K Ramirez-Fort
BACKGROUND: Fractional CO2 laser and autologous hair transplantation are independently effective in the treatment of refractory and stable vitiligo. OBJECTIVE: The authors' purpose was to evaluate the therapeutic efficacy of fractional CO2 laser pretreatment compared with autologous hair transplantation and phototherapy alone for refractory and stable vitiligo. METHODS: A total of 20 patients with refractory and stable vitiligo were enrolled from our clinic...
September 2016: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
Kristin L Bater, Masaru Ishii, Andrew Joseph, Peiyi Su, Jason Nellis, Lisa E Ishii
Importance: Hair transplant is among the most common cosmetic services sought by men, with more than 11 000 procedures performed in 2014. Despite its growing popularity, the effect of hair transplant on societal perceptions of youth, attractiveness, or facets of workplace and social success is unknown. Objectives: To determine whether hair transplant improves observer ratings of age, attractiveness, successfulness, and approachability in men treated for androgenetic alopecia and to quantify the effect of hair transplant on each of these domains...
August 25, 2016: JAMA Facial Plastic Surgery
Volkan Zeybek, Yücel Arisoy
BACKGROUND/AIM: Peripheral blood DNA profiles are often used in forensic identification and paternity investigations. Currently, because of the increasing number of patients who undergo transplantation, determining the history of transplantation has gained importance in forensic cases. The aim of this study was to investigate the potential of genetic chimerism analysis of blood, hair follicle, and buccal swab samples for the forensic identification of transplant patients. MATERIALS AND METHODS: Blood, hair follicle, and buccal swab samples from five patients who had undergone allogeneic peripheral blood stem cell transplantation (allo-PBSCT) and 35 patients who had undergone liver transplantation were analyzed...
2016: Turkish Journal of Medical Sciences
Young-Cheon Na, Raekil Park, Hii-Sun Jeong, Jae Hyun Park
BACKGROUND: There have been few studies of the action of epinephrine injected into scalp tissue, or whether the action of epinephrine differs according to vascular anatomy within the same surgical field. Effective perioperative control of bleeding is critical during hair transplantation due to its time-consuming nature. OBJECTIVE: To identify the vasoconstriction time of epinephrine by concentration and injection site in the scalp tissue. METHODS: Twenty-five volunteers were injected with epinephrine at concentrations of 1:400,000, 1:200,000, 1:100,000, and 1:50,000 in the path of the supraorbital artery on the anterior hairline in the midfrontal area (Point A) and at the frontotemporal junction of the frontal hairline (Point B)...
September 2016: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
Xiaoxiao Wang, Xusheng Wang, Jianjun Liu, Ting Cai, Ling Guo, Shujuan Wang, Jinmei Wang, Yanpei Cao, Jianfeng Ge, Yuyang Jiang, Edward E Tredget, Mengjun Cao, Yaojiong Wu
: : Stem cell-based organ regeneration is purported to enable the replacement of impaired organs in the foreseeable future. Here, we demonstrated that a combination of cultured epidermal stem cells (Epi-SCs) derived from the epidermis and skin-derived precursors (SKPs) was capable of reconstituting functional hair follicles and sebaceous glands (SG). When Epi-SCs and SKPs were mixed in a hydrogel and implanted into an excisional wound in nude mice, the Epi-SCs formed de novo epidermis along with hair follicles, and SKPs contributed to dermal papilla in the neogenic hair follicles...
July 25, 2016: Stem Cells Translational Medicine
Wenluo Cao, Fang Liu, Yasuyuki Amoh, Robert M Hoffman
Isolated whisker follicles from nestin-driven green fluorescent protein (ND-GFP) mice, containing hair-associated pluripotent (HAP) stem cells, were histocultured in three dimensions on Gelfoam(®) for 3 weeks for subsequent transplantation to the spinal cord in order to heal an induced injury with the HAP stem cells. The hair shafts were removed from Gelfoam(®)-histocultured whisker follicles, and the remaining parts of the whisker follicles, containing GFP-nestin-expressing (HAP) stem cells, were transplanted into the injured spinal cord of nude mice, along with the Gelfoam(®)...
2016: Methods in Molecular Biology
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