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https://www.readbyqxmd.com/read/29166502/outcomes-of-long-term-treatments-of-type-i-hereditary-angioedema-in-a-turkish-family
#1
Gulsen Akoglu, Belgin Kesim, Gokhan Yildiz, Ahmet Metin
BACKGROUND: Hereditary angioedema is a rare autosomal dominantly inherited immunodeficiency disorder characterized by potentially life-threatening angioedema attacks. OBJECTIVE: We aimed to investigate the clinical and genetic features of a family with angioedema attacks. METHODS: The medical history, clinical features and C1-INH gene mutation of a Turkish family were investigated and outcomes of long-term treatments were described. RESULTS: Five members had experienced recurrent swellings on the face and extremities triggered by trauma...
September 2017: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/29165895/adaptation-and-validation-of-the-turkish-version-of-the-nasal-obstruction-symptom-evaluation-scale
#2
Ozlem Onerci Celebi, Ela Araz Server, Ozgur Yigit, Ecem Sevim Longur
BACKGROUND: The Nasal Obstruction Symptom Evaluation (NOSE) scale is a questionnaire used to assess the quality of life in patients with nasal obstruction. The aim of this study was to validate the Turkish translation of the NOSE questionnaire. METHODS: The NOSE questionnaire was translated into Turkish and then back to English. Fifty patients with septal deviation leading to nasal obstruction and 50 healthy subjects without any nasal complaints and pathologies were recruited into the study...
November 22, 2017: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/29165107/description-of-the-healthy-eating-indices-based-diet-quality-in-turkish-adults-a-cross-sectional-study
#3
Eda Koksal, Merve Seyda Karacil Ermumcu, Hande Mortas
OBJECTIVES: This study aims to describe the dietary status of Turkish adults using two different versions of the Healthy Eating Index (HEI). METHODS: In this cross sectional study, 494 healthy participants (311 females) with randomly selected and living in Ankara were included between September 2013 and March 2014. A questionnaire was completed and anthropometric measurements (weight and height) were performed. The 24-h dietary recall of individuals was collected...
March 20, 2017: Environmental Health and Preventive Medicine
https://www.readbyqxmd.com/read/29162349/agreement-between-parents-and-clinicians-on-the-communication-function-levels-and-relationship-of-classification-systems-of-children-with-cerebral-palsy
#4
Akmer Mutlu, Özgün Kaya Kara, Ayşe Livanelioğlu, Sevilay Karahan, Halil Alkan, Bilge Nur Yardımcı, Mary Jo Cooley Hidecker
BACKGROUND: Functional classification systems have generally been used by clinicians and recently by parents to classify various functions of children with cerebral palsy (CP). OBJECTIVE: This study evaluated the agreement between clinicians and parents when classifying the communication function of children with CP using the Communication Function Classification System (CFCS). In addition, the relationships between the Gross Motor Function Classification System - Expanded and Revised (GMFCS-E&R), the Manual Ability Classification System (MACS), and CFCS were investigated...
November 14, 2017: Disability and Health Journal
https://www.readbyqxmd.com/read/29159724/turkish-case-of-ethylmalonic-encephalopathy-misdiagnosed-as-short-chain-acyl-coa-dehydrogenase-deficiency
#5
Fatma Derya Bulut, Deniz Kör, Berna Şeker-Yılmaz, Gülen Gül-Mert, Sebile Kılavuz, Neslihan Önenli-Mungan
Ethylmalonic encephalopathy is a very rare autosomal recessively inherited inborn error of metabolism; characterized by encephalopathy, recurrent petechiae without bleeding diathesis, chronic diarrhea, and orthostatic acrocyanosis. Here, we describe a case of ethylmalonic encephalopathy with late onset neurologic symptoms and a confusing family history of two deceased brothers with the wrong suspicion of short chain acyl-CoA dehydrogenase deficiency.
November 20, 2017: Metabolic Brain Disease
https://www.readbyqxmd.com/read/29159163/association-of-lct-13910-c-t-polymorphism-and-colorectal-cancer
#6
Genco Gençdal, Esin Salman, Ömer Özütemiz, Ulus S Akarca
Purpose: The activity of epithelial lactase (LCT) is associated with a polymorphism 13910 bp upstream in the lactase encoding gene. Because the association between the LCT-13910 polymorphism and the risk for colorectal cancer is not clear, we investigated the role of the LCT-13910 polymorphism as a potential risk factor for colorectal cancer and colorectal polyps in the Turkish population. Methods: One hundred sixty-six subjects (74 with polyps, 44 with colorectal cancer, 48 controls), who had undergone a total colonoscopy between January 2012 and November 2012 in our endoscopy unit were genotyped for the LCT-13910 polymorphism by using the polymerase chain reaction and minisequencing...
October 2017: Annals of Coloproctology
https://www.readbyqxmd.com/read/29156870/a-fully-liquid-dtap-ipv-hb-prp-t-hexavalent-vaccine-for-primary-and-booster-vaccination-of-healthy-turkish-infants-and-toddlers
#7
Mehmet Ceyhan, İnci Yıldırım, Hasan Tezer, İlker Devrim, Emmanuel Feroldi
Background/aim: Immunogenicity and safety of a primary series of a fully liquid, hexavalent DTaP-IPV-HB-PRP-T vaccine given at 2, 3, and 4 months of age compared to licensed comparators and a DTaP-IPV-HB-PRP-T booster at 15?18 months were evaluated. Materials and methods: This was a Phase III, randomized, open-label trial. Primary series (no hepatitis B [HB] at birth) of DTaP-IPV-HB-PRP-T (N = 155) (group 1) or licensed control vaccines (DTaP-IPV//PRP-T and standalone HB: N = 155) (group 2) and DTaP-IPV-HB-PRP-T booster were administered...
August 23, 2017: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/29156868/a-nationwide-evaluation-of-off-label-drug-utilization-in-turkey
#8
Emine Nur Özdamar, Ahmet Akıcı, Ali Alkan, Banu Bayar, Hakkı Gürsöz
Background/aim: Off-label drug use (OLDU) is under the control of the Turkish Medicines and Medical Devices Agency (TMMDA) in Turkey. It was aimed to investigate demographic and medical features of patients with OLDU applications in Turkey. Materials and methods: A total of 4426 electronic OLDU application records of the TMMDA were evaluated retrospectively. Information regarding patients? demographic characteristics, diagnoses, requested drugs, institutions, and specialties of the physicians were evaluated...
August 23, 2017: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/29156867/cross-cultural-adaptation-and-psychometric-assessment-of-the-turkish-version-of-the-vulnerability-to-abuse-screening-scale
#9
Güler Duru Aşiret, Gülcan Bağcıvan, Münevver Özcan, Beste Başak Eröksüz, Nalan Akbayrak, Nuran Akdemir
Background/aim: The aim of this study was to evaluate the reliability and validity of the Turkish version of the Vulnerability to Abuse Screening Scale (VASS). Materials and methods: This was a methodological study. The sample included 140 elderly individuals. Data were collected by using a questionnaire form, the VASS, and the Geriatric Depression Scale (GDS). The Cronbach alpha value was calculated and test?retest reliability was tested for the reliability analyses. Results: The Cronbach alpha value calculated for the VASS (12 items) was 0...
August 23, 2017: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/29156862/the-prevalence-of-abdominal-obesity-is-remarkable-for-underweight-and-normal-weight-adolescent-girls
#10
Nilüfer Acar Tek, Nevin Şanlıer, Duygu Türközü
Background/aim: Obesity is a global public health challenge. This study was carried out in order to determine the prevalence of obesity and abdominal obesity in Turkish adolescent girls. Materials and methods: A cross-sectional study was conducted in a total of 1111 adolescent girls aged 12?18 years. The subjects were classified into four groups: underweight, normal, overweight, and obese. Abdominal obesity was defined according to waist circumference (WC) ≥ 90th percentile for Turkish adolescent population references (12-17 years) and waist-to-height ratio (WHtR) ≥ 0...
August 23, 2017: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/29156508/validity-and-reliability-of-the-turkish-version-of-the-readiness-for-hospital-discharge-scale-short-form
#11
Sıdıka Kaya, Gulay Sain Guven, Mesut Teleş, Cahit Korku, Seda Aydan, Ahmet Kar, Nazan Kartal, Gülsüm Şeyma Koca, Ahmet Yıldız
AIM: The aim of this study is to test the validity and reliability of the Turkish version of the readiness for hospital discharge scale/short form. BACKGROUND: Assessment of readiness for discharge from the patient's perspective is becoming increasingly important for patient safety, satisfaction and various patient outcomes such as readmission, health service utilization and mortality. The readiness for hospital discharge scale/short form allows health care providers to determine patients' discharge readiness...
November 20, 2017: Journal of Nursing Management
https://www.readbyqxmd.com/read/29154262/review-of-scapular-movement-disorders-among-office-workers-having-ergonomic-risk
#12
Ö Depreli, E Angın
BACKGROUND: Work-related musculoskeletal disorders are the most common health problems which affect millions of office workers. OBJECTIVE: The objective of this study is to determine scapular positioning at rest and different anatomical planes, the assessment of pain, postural changes and the functionality of upper extremity that is caused by the lack of ergonomic principles among office workers of civil servants in TRNC (Turkish Republic of Northern Cyprus). METHODS: One hundred and eighty-three individuals participated in the study and 2 groups were created by grand scores of Rapid Upper Limb Assessment (RULA) tool...
November 17, 2017: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/29153306/autologous-hematopoietic-progenitor-cell-mobilization-and-collection-in-adult-patients-presenting-with-multiple-myeloma-and-lymphoma-a-position-statement-from-the-turkish-society-of-apheresis-tsa
#13
REVIEW
Emre Tekgündüz, Mutlu Arat, Hakan Göker, Hakan Özdoğu, Leylagül Kaynar, Seçkin Çağırgan, Mehmet Ali Erkurt, Filiz Vural, İlhami Kiki, Fevzi Altuntaş, Fatih Demirkan
Autologous hematopoietic cell transplantation (AHCT) is a routinely used procedure in the treatment of adult patients presenting with multiple myeloma (MM), Hodgkin lymphoma (HL) and various subtypes of non-Hodgkin lymphoma (NHL) in upfront and relapsed/refractory settings. Successful hematopoietic progenitor cell mobilization (HPCM) and collection are the rate limiting first steps for application of AHCT. In 2015, almost 1700 AHCT procedures have been performed for MM, HL and NHL in Turkey. Although there are recently published consensus guidelines addressing critical issues regarding autologous HPCM, there is a tremendous heterogeneity in terms of mobilization strategies of transplant centers across the world...
November 10, 2017: Transfusion and Apheresis Science
https://www.readbyqxmd.com/read/29153305/current-practice-of-autologous-hematopoietic-progenitor-cell-mobilization-in-adult-patients-with-multiple-myeloma-and-lymphoma-the-results-of-a-survey-from-turkish-hematology-research-and-education-group-threg
#14
REVIEW
Emre Tekgündüz, Fatih Demirkan, Filiz Vural, Hakan Göker, Hakan Özdoğu, İlhami Kiki, İsmet Aydoğdu, Leylagül Kaynar, Mehmet Ali Erkurt, Seçkin Çağırgan, Sevgi Beşışık, Simten Dağdaş, Ebru Koca, Gürhan Kadıköylü, Eren Gündüz, Mehmet Yılmaz, Hüseyin Beköz, Ali Uğur Ural, Abdülkadir Baştürk, Mutlu Arat, Murat Albayrak, Erman Öztürk, Alev Akyol, Ali Zahit Bolaman, Oral Nevruz, Hasan Atilla Özkan, Gökhan Özgür, Fevzi Altuntaş
Autologous hematopoietic cell transplantation (AHCT) is an established treatment option for adult patients presenting with multiple myeloma (MM), Hodgkin lymphoma (HL) and various subtypes of non-Hodgkin lymphoma (NHL) in upfront and/or relapsed/refractory disease settings. Although there are recently published consensus guidelines addressing critical issues regarding autologous hematopoietic progenitor cell mobilization (HPCM), mobilization strategies of transplant centers show high variability in terms of routine practice...
November 9, 2017: Transfusion and Apheresis Science
https://www.readbyqxmd.com/read/29151380/stakeholders-perceptions-of-health-technology-assessment-in-turkey
#15
Kirstin Ozturk, Bilgehan Karadayı, Olgun Şener
BACKGROUND: In April of 2014, the Turkish Ministry of Health held the First Annual Health Technology Assessment (HTA) Meeting in Antalya. OBJECTIVES: The objectives were to understand the perceptions of stakeholders regarding the current status of HTA and document their recommendations and strategies for promoting systematic use of HTA in Turkey. METHODS: The study was conducted using a qualitative written survey assessing current compliance with the fifteen HTA principles suggested by Drummond et al...
November 20, 2017: International Journal of Technology Assessment in Health Care
https://www.readbyqxmd.com/read/29151334/investigation-of-glucocorticoid-receptor-and-calpain-10-gene-polymorphisms-in-turkish-patients-with-type-2-diabetes-mellitus
#16
Naciye Selcen Bayramcı, Leyla Açık, Çağdaş Kalkan, İlhan Yetkin
Background/aim: We proposed to investigate the role of calpain-10 (CAPN10) gene single nucleotide polymorphism (SNP)-19 and SNP-44 and glucocorticoid receptor (NR3C1) gene N363S polymorphisms in Turkish patients with type 2 diabetes mellitus (T2DM).Materials and methods: Peripheral blood samples were obtained from 125 patients with T2DM and 112 healthy volunteers. Genotyping was carried out by the polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method. Results: There were no statistically significant differences found between the allele and genotype frequencies of CAPN10 SNP-19, CAPN10 SNP-44, and NR3C1 N363S polymorphisms and T2DM development (P > 0...
November 13, 2017: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/29151319/patients-attitudes-and-knowledge-about-drug-use-a-survey-in-turkish-family-healthcare-centres-and-state-hospitals
#17
Ahmet Akıcı, Salih Mollahaliloğlu, Başak Dönertaş, Şenay Özgülcü, Ali Alkan, Nesrin Filiz Başaran
Background/aim: Irrational drug use is a common problem. This study aimed to evaluate patients' knowledge and habits concerning drug use, and compare them in terms of some sociodemographic characteristics. Materials and methods: A face-to-face questionnaire was given to outpatients from family healthcare centres (FHCs) and state hospitals (SHs) in 12 provinces in Turkey during May 2010. A total of 4470 patients (FHCs: 2209; SHs: 2261) responded to the questionnaire (response rate: 93.1%). Results: Getting prescriptions without a physical examination was common (second place in FHCs; third place in SHs); 51...
November 13, 2017: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/29151297/the-clinical-features-and-outcomes-of-turkish-patients-with-igg4-related-disease-a-single-center-experience
#18
Ömer Karadağ, Abdulsamet Erden, Emine Arzu Ayhan, Ertuğrul Çağrı Bölek, Umut Kalyoncu, Berkan Armağan, Alper Sarı, Levent Kılıç, Ali Akdoğan, Tuncay Hazırolan, Bülent Akdoğan, Şaziye Şule Apraş Bilgen, Dilek Baydar, Sedat Kiraz, Ali İhsan Ertenli
Background/aim: Since the majority of the IgG4-related disease (IgG4-RD) patients in the literature are from the Far East and the United States, there is a lack of large series from other parts of the world. We aimed to identify the clinical characteristics and outcome of Turkish IgG4-RD patients from a tertiary center. Materials and methods: Fifty-two patients classified as having definite IgG4-RD according to comprehensive diagnostic criteria were included in the study. Patients not fulfilling the definite criteria due to lack of pathologic specimen and/or serum IgG4 levels were excluded (n = 47)...
November 13, 2017: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/29151049/contribution-of-short-sleep-duration-to-ethnic-differences-in-cardiovascular-disease-results-from-a-cohort-study-in-the-netherlands
#19
Kenneth Anujuo, Charles Agyemang, Marieke B Snijder, Girardin Jean-Louis, Bert-Jan van den Born, Ron J G Peters, Karien Stronks
OBJECTIVES: We analysed association between short sleep duration and prevalence of cardiovascular disease (CVD) in a multiethnic population living in the Netherlands, and the contribution of short sleep to the observed ethnic differences in the prevalence of CVD, independent of CVD risk factors. METHODS: 20 730 participants (aged 18-71 years) of the HELIUS (Healthy Life in an Urban Setting) Study were investigated. Self-reported sleep duration was classified as: short (<7 hours/night) and healthy (7-9 hours/night)...
November 17, 2017: BMJ Open
https://www.readbyqxmd.com/read/29148404/other-autoinflammatory-disease-genes-in-an-fmf-prevalent-population-a-homozygous-mvk-mutation-and-a-novel-heterozygous-tnfrsf1a-mutation-in-two-different-turkish-families-with-clinical-fmf
#20
İlker Karacan, Serdal Uğurlu, Aslıhan Tolun, Eda Tahir Turanlı, Huri Özdoğan
OBJECTIVES: No MEFV mutations are detected in approximately 10% of the patients with clinical FMF in populations where the disease is highly prevalent. Causative mutations were searched in other genes in two such families with "MEFV negative clinical FMF". METHODS: Father and daughter of family A had attacks of fever, abdominal pain and AA amyloidosis. The two sibs of family B complained of febrile episodes with abdominal pain and arthritis. The patients were clinically investigated...
October 27, 2017: Clinical and Experimental Rheumatology
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