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https://www.readbyqxmd.com/read/28449126/results-of-the-answer-trial-using-the-pulserider-for-the-treatment-of-broad-necked-bifurcation-aneurysms
#1
Alejandro M Spiotta, Colin P Derdeyn, Satoshi Tateshima, Jay Mocco, R Webster Crowley, Kenneth C Liu, Lee Jensen, Koji Ebersole, Alan Reeves, Demetrius K Lopes, Ricardo A Hanel, Eric Sauvageau, Gary Duckwiler, Adnan Siddiqui, Elad Levy, Ajit Puri, Lee Pride, Roberta Novakovic, M Imran Chaudry, Raymond D Turner, Aquilla S Turk
BACKGROUND: The safety and probable benefit of the PulseRider (Pulsar Vascular, Los Gatos, California) for the treatment of broad-necked, bifurcation aneurysms was studied in the context of the prospective, nonrandomized, single arm clinical trial-the Adjunctive Neurovascular Support of Wide-neck aneurysm Embolization and Reconstruction (ANSWER) Trial. OBJECTIVE: To present the results of the United States cases employing the PulseRider device as part of the ANSWER clinical trial...
April 25, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28448379/effect-of-an-outpatient-pulmonary-rehabilitation-program-on-exercise-tolerance-and-asthma-control-in-obese-asthma-patients
#2
Yasemin Türk, Astrid van Huisstede, Frits M E Franssen, Pieter S Hiemstra, Arjan Rudolphus, Cristian Taube, Gert-Jan Braunstahl
PURPOSE: To compare the effects of an outpatient pulmonary rehabilitation (PR) program on exercise tolerance and asthma control in obese and nonobese patients with asthma. METHODS: Nonobese (body mass index [BMI] <30 kg/m) and obese (BMI ≥ 30 kg/m) patients with asthma who participated in a local multidisciplinary 12-week PR program were analyzed retrospectively. Effects of PR were assessed by changes in 6-minute walking distance (6MWD) and Asthma Control Questionnaire (ACQ)...
May 2017: Journal of Cardiopulmonary Rehabilitation and Prevention
https://www.readbyqxmd.com/read/28447815/development-of-the-healthcare-triggering-questionnaire-in-adult-sexual-abuse-survivors
#3
Julie B Schnur, William F Chaplin, Kiran Khurshid, Jazmin N Mogavero, Rachel E Goldsmith, Young-Sun Lee, Leib Litman, Guy H Montgomery
OBJECTIVE: One in 4 women and 1 in 10 men in the United States are survivors of sexual abuse (SA). For these survivors, healthcare experiences may trigger memories, thoughts, feelings or sensations related to this past abuse. Such triggering can be associated with negative responses to healthcare (e.g., anxiety, avoidance). However, to date, no healthcare triggering assessment tool exists. Therefore, the study goal was to describe the prevalence of healthcare triggering, to develop a brief Healthcare Triggering Questionnaire (HTQ), and to examine its initial validity...
April 27, 2017: Psychological Trauma: Theory, Research, Practice and Policy
https://www.readbyqxmd.com/read/28442189/exploring-how-residents-who-partially-participate-in-family-planning-training-determine-their-level-of-participation
#4
Jema K Turk, Felisa Preskill, Alecia Fields, Uta Landy, Jody E Steinauer
OBJECTIVES: The Accreditation Council for Graduate Medical Education (ACGME) requires that obstetrics and gynecology residency programs provide access to abortion training, though residents may elect to opt out of participating due to religious or moral objections. While clinical benefits of partial participation have previously been explored, our study aimed to explore how residents navigate partial participation in abortion training and determine their limits. STUDY DESIGN: This study was qualitative in nature...
April 22, 2017: Women's Health Issues: Official Publication of the Jacobs Institute of Women's Health
https://www.readbyqxmd.com/read/28440438/loss-of-heterozygosity-in-fancg-fancf-and-brip1-from-head-and-neck-squamous-cell-carcinoma-of-the-oral-cavity
#5
Christin Türke, Susanne Horn, Carola Petto, Dirk Labudde, Günter Lauer, Gretel Wittenburg
Recent advances have been made in the understanding of Fanconi anemia (FA), a hereditary disease that increases the risk for head and neck squamous cell carcinomas (HNSCC) by 500- to 700-fold. FA patients harbour germline mutations in genes of cellular DNA repair pathways that are assumed to facilitate the accumulation of mutations during HNSCC development. Mutations in these FA genes may also contribute to HNSCC in general. In the present study, we analysed three FA genes; FANCF, FANCG and BRIP1, that are involved in the repair of DNA inter strand cross-links, in HNSCC and their potential role for patient survival...
April 24, 2017: International Journal of Oncology
https://www.readbyqxmd.com/read/28437124/marijuana-and-tobacco-cigarettes-estimating-their-behavioral-economic-relationship-using-purchasing-tasks
#6
Erica N Peters, Zachary R Rosenberry, Gillian L Schauer, Kevin E O'Grady, Patrick S Johnson
Although marijuana and tobacco are commonly coused, the nature of their relationship has not been fully elucidated. Behavioral economics has characterized the relationship between concurrently available commodities but has not been applied to marijuana and tobacco couse. U.S. adults ≥18 years who coused marijuana and tobacco cigarettes were recruited via Mechanical Turk, a crowdsourcing service by Amazon. Participants (N = 82) completed online purchasing tasks assessing hypothetical marijuana or tobacco cigarette puff consumption across a range of per-puff prices; 2 single-commodity tasks assessed these when only 1 commodity was available, and 2 cross-commodity tasks assessed these in the presence of a concurrently available fixed-price commodity...
April 24, 2017: Experimental and Clinical Psychopharmacology
https://www.readbyqxmd.com/read/28435846/psychometric-properties-and-characteristics-of-the-north-east-visual-hallucinations-interview-in-parkinson-s-disease
#7
Kelsey A Holiday, Eva Pirogovsky-Turk, Vanessa L Malcarne, J Vincent Filoteo, Irene Litvan, Stephanie L Lessig, David Song, Dawn M Schiehser
BACKGROUND: Visual Hallucinations (VH) are a common symptom experienced by individuals with Parkinson's disease (PD); however, a validated measure of VH has yet to be established for this population. The North-East Visual Hallucinations Interview (NEVHI), a promising VH measure, has not been well validated in PD. The aim of this study was to evaluate the convergent and discriminant validity of the NEVHI as well as the proportional identification and characteristics of VH in PD. METHODS: One hundred seventeen individuals with PD completed the NEVHI as well as evaluations of psychological, cognitive, motor, and visual functioning as measures of convergent and divergent validity...
March 16, 2017: Movement Disorders Clinical Practice
https://www.readbyqxmd.com/read/28435281/first-do-no-harm-institutional-betrayal-and-trust-in-health-care-organizations
#8
Carly Parnitzke Smith
PURPOSE: Patients' trust in health care is increasingly recognized as important to quality care, yet questions remain about what types of health care experiences erode trust. The current study assessed the prevalence and impact of institutional betrayal on patients' trust and engagement in health care. PARTICIPANTS AND METHODS: Participants who had sought health care in the US in October 2013 were recruited from an online marketplace, Amazon's Mechanical Turk. Participants (n = 707; 73% Caucasian; 56...
2017: Journal of Multidisciplinary Healthcare
https://www.readbyqxmd.com/read/28428613/differential-regulation-of-pkd-isoforms-in-oxidative-stress-conditions-through-phosphorylation-of-a-conserved-tyr-in-the-p-1-loop
#9
Mathias Cobbaut, Rita Derua, Heike Döppler, Hua Jane Lou, Sandy Vandoninck, Peter Storz, Benjamin E Turk, Thomas Seufferlein, Etienne Waelkens, Veerle Janssens, Johan Van Lint
Protein kinases are essential molecules in life and their crucial function requires tight regulation. Many kinases are regulated via phosphorylation within their activation loop. This loop is embedded in the activation segment, which additionally contains the Mg(2+) binding loop and a P + 1 loop that is important in substrate binding. In this report, we identify Abl-mediated phosphorylation of a highly conserved Tyr residue in the P + 1 loop of protein kinase D2 (PKD2) during oxidative stress. Remarkably, we observed that the three human PKD isoforms display very different degrees of P + 1 loop Tyr phosphorylation and we identify one of the molecular determinants for this divergence...
April 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28425122/mean-intercept-anisotropy-analysis-of-porous-media-ii-conceptual-shortcomings-of-the-mil-tensor-definition-and-minkowski-tensors-as-an-alternative
#10
Michael A Klatt, Gerd E Schröder-Turk, Klaus Mecke
PURPOSE: Structure-property relations, which relate the shape of the microstructure to physical properties such as transport or mechanical properties, need sensitive measures of structure. What are suitable fabric tensors to quantify the shape of anisotropic heterogeneous materials? The mean intercept length is among the most commonly used characteristics of anisotropy in porous media, e. g., of trabecular bone in medical physics. Yet, in this series of two papers we demonstrate that it has conceptual shortcomings that limit the validity of its results...
April 20, 2017: Medical Physics
https://www.readbyqxmd.com/read/28425119/mean-intercept-anisotropy-analysis-of-porous-media-i-analytic-formulae-for-anisotropic-boolean-models
#11
Michael A Klatt, Gerd E Schröder-Turk, Klaus Mecke
PURPOSE: Structure-property relations, which relate the shape of the microstructure to physical properties such as transport or mechanical properties, need sensitive measures of structure. What are suitable fabric tensors to quantify the shape of anisotropic heterogeneous materials? The mean intercept length is among the most commonly used characteristics of anisotropy in porous media, for example, of trabecular bone in medical physics. METHODS: We analyze the orientation-biased Boolean model, a versatile stochastic model that represents microstructures as overlapping grains with an orientation bias towards a preferred direction...
April 20, 2017: Medical Physics
https://www.readbyqxmd.com/read/28417113/temporal-registration-in-in-utero-volumetric-mri-time-series
#12
Ruizhi Liao, Esra A Turk, Miaomiao Zhang, Jie Luo, P Ellen Grant, Elfar Adalsteinsson, Polina Golland
We present a robust method to correct for motion and deformations in in-utero volumetric MRI time series. Spatio-temporal analysis of dynamic MRI requires robust alignment across time in the presence of substantial and unpredictable motion. We make a Markov assumption on the nature of deformations to take advantage of the temporal structure in the image data. Forward message passing in the corresponding hidden Markov model (HMM) yields an estimation algorithm that only has to account for relatively small motion between consecutive frames...
October 2016: Medical Image Computing and Computer-assisted Intervention: MICCAI ..
https://www.readbyqxmd.com/read/28412893/public-attitudes-and-feelings-of-warmth-toward-women-and-men-experiencing-depression-during-the-perinatal-period
#13
Jennifer N Felder, Sarah Banchefsky, Bernadette Park, Sona Dimidjian
OBJECTIVE: Depression is a major public health concern and often goes untreated. In response to a growing body of research documenting stigma as a barrier to depression care, this study focused on examining public stigma toward potentially vulnerable subpopulations. METHODS: Participants (N=241) were recruited from Amazon's Mechanical Turk and randomly assigned to provide anonymous ratings on attitudes and feelings of warmth toward pregnant women and expectant fathers experiencing depression, mothers and fathers experiencing postpartum depression, or women and men experiencing depression during nonperinatal periods...
April 17, 2017: Psychiatric Services: a Journal of the American Psychiatric Association
https://www.readbyqxmd.com/read/28412153/the-effect-of-counseling-on-willingness-to-use-a-hypothetical-medication-and-perceptions-of-medication-safety
#14
Michael Bitonti, Payal Patel, Rebecca Dickinson, Peter Knapp, Susan J Blalock
BACKGROUND: Poor medication adherence is an ongoing issue, and contributes to increased hospitalizations and healthcare costs. Although most adverse effects are rare, the perceived risk of adverse effects may contribute to low adherence rates. OBJECTIVES: The objective of this study was to determine how adverse effect likelihood and pharmacist counseling on adverse effect prevention affects individuals': (1) willingness to use a hypothetical medication and (2) perceptions of medication safety...
March 31, 2017: Research in Social & Administrative Pharmacy: RSAP
https://www.readbyqxmd.com/read/28407887/how-to-address-continued-health-care-differences-and-disparities-among-people-with-disability
#15
EDITORIAL
Margaret A Turk, Suzanne McDermott
No abstract text is available yet for this article.
April 2017: Disability and Health Journal
https://www.readbyqxmd.com/read/28405482/the-relationship-between-serum-carbonic-anhydrase-i-ii-autoantibody-levels-and-diabetic-retinopathy-in-type-1-diabetes-patients
#16
Adem Türk, Süleyman Mollamehmetoğlu, Ahmet Alver, Ahmet Menteşe, İrfan Nuhoğlu, Cihangir Erem, Halil İbrahim İmamoğlu
OBJECTIVES: To investigate the relationship between serum carbonic anhydrase I-II (CA-I and II) autoantibody levels and diabetic retinopathy (DRP) in cases with type 1 diabetes. MATERIALS AND METHODS: A total of 37 type-1 diabetic patients, 17 with DRP (group 1) and 20 without (group 2), and 38 healthy control subjects (group 3) were included. CA-I and CA-II autoantibody levels were measured in serum samples obtained from each of the three groups and compared statistically...
April 2017: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/28403888/the-relationship-between-ethnic-composition-of-the-residential-environment-and-self-reported-health-among-turks-and-moroccans-in-amsterdam
#17
Eleonore M Veldhuizen, Umar Z Ikram, Sjoerd de Vos, Anton E Kunst
BACKGROUND: Previous studies from the US and UK suggest that neighbourhood ethnic composition is associated with health, positive or negative, depending on the health outcome and ethnic group. We examined the association between neighbourhood ethnic composition and self-reported health in these groups in Amsterdam, and we aimed to explore whether there is spatial variation in this association. METHODS: We used micro-scale data to describe the ethnic composition in buffers around the home location of 2701 Turks and 2661 Moroccans...
April 12, 2017: International Journal of Health Geographics
https://www.readbyqxmd.com/read/28402344/radiopacity-of-luting-cements-as-a-potential-factor-in-peri-implantitis-an-in-vitro-comparative-study
#18
Ebru Cal, Pelin Guneri, Sena Unal, Aysşe Gözde Türk, Mubin Ulusoy, Hayal Boyacioglu
The aim of this study was to establish the radiopacity of cements used in implant-retained fixed partial dentures with respect to implant material, enamel, and dentin. A sample of 10 specimens of 13 different cements, implants, enamel, and dentin were prepared. Radiographs of the specimens and aluminum step wedges were acquired. Mean gray values of specimens were measured using digital imaging software. Kolmogorov-Smirnov and Shapiro-Wilk normality tests and independent t test were used (P = .05). Implantlink Semi, Premier, and Dentotemp had the lowest radiopacity values; GC FujiTemp LT, Multilink Implant, Poly-F Plus, Cavex-Temporary, and Panavia SA showed the highest...
May 2017: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/28396304/comparing-crowdsourcing-and-friendsourcing-a-social-media-based-feasibility-study-to-support-alzheimer-disease-caregivers
#19
Daniel Robert Bateman, Erin Brady, David Wilkerson, Eun-Hye Yi, Yamini Karanam, Christopher M Callahan
BACKGROUND: In the United States, over 15 million informal caregivers provide unpaid care to people with Alzheimer disease (AD). Compared with others in their age group, AD caregivers have higher rates of stress, and medical and psychiatric illnesses. Psychosocial interventions improve the health of caregivers. However, constraints of time, distance, and availability inhibit the use of these services. Newer online technologies, such as social media, online groups, friendsourcing, and crowdsourcing, present alternative methods of delivering support...
April 10, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/28394023/crowdcurio-an-online-crowdsourcing-platform-to-facilitate-climate-change-studies-using-herbarium-specimens
#20
Charles G Willis, Edith Law, Alex C Williams, Brian F Franzone, Rebecca Bernardos, Lian Bruno, Claire Hopkins, Christian Schorn, Ella Weber, Daniel S Park, Charles C Davis
Phenology is a key aspect of plant success. Recent research has demonstrated that herbarium specimens can provide important information on plant phenology. Massive digitization efforts have the potential to greatly expand herbarium-based phenological research, but also pose a serious challenge regarding efficient data collection. Here, we introduce CrowdCurio, a crowdsourcing tool for the collection of phenological data from herbarium specimens. We test its utility by having workers collect phenological data (number of flower buds, open flowers and fruits) from specimens of two common New England (USA) species: Chelidonium majus and Vaccinium angustifolium...
April 10, 2017: New Phytologist
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