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https://www.readbyqxmd.com/read/28816465/on-informing-jurors-of-potential-sanctions
#1
Jennifer Teitcher, Nicholas Scurich
Two experiments tested (a) whether jurors make assumptions about the potential punishment that would follow from a guilty verdict, (b) whether those assumptions influence jurors' implicit threshold for reasonable doubt, and (c) whether informing jurors of the potential punishment additionally influences their implicit threshold. Experiment 1 manipulated the alleged crime (grand theft vs. manslaughter) holding all other factors constant, and found that mock jurors (n = 102, recruited via Amazon Mechanical Turk) had different expectations about the relative punishments but that these expectations did not affect their implicit threshold for reasonable doubt...
August 17, 2017: Law and Human Behavior
https://www.readbyqxmd.com/read/28813899/the-effects-of-auditory-and-visual-cues-on-timing-synchronicity-for-robotic-rehabilitation
#2
Brittney A English, Ayanna M Howard
In this paper, we explore how the integration of auditory and visual cues can help teach the timing of motor skills for the purpose of motor function rehabilitation. We conducted a study using Amazon's Mechanical Turk in which 106 participants played a virtual therapy game requiring wrist movements. To validate that our results would translate to trends that could also be observed during robotic rehabilitation sessions, we recreated this experiment with 11 participants using a robotic wrist rehabilitation system as means to control the therapy game...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28812674/red-list-of-a-black-box
#3
Helen R P Phillips, Erin K Cameron, Olga Ferlian, Manfred Türke, Marten Winter, Nico Eisenhauer
No abstract text is available yet for this article.
March 23, 2017: Nature ecology & evolution
https://www.readbyqxmd.com/read/28809134/cancer-treatment-experiences-among-survivors-of-childhood-sexual-abuse-a-qualitative-investigation-of-triggers-and-reactions-to-cumulative-trauma
#4
Julie B Schnur, Matthew J Dillon, Rachel E Goldsmith, Guy H Montgomery
OBJECTIVE: Some 25% of women and 8% of men in the United States have experienced childhood sexual abuse (CSA) before the age of 18. For these individuals, healthcare visits and interactions can be retraumatizing due to perceived similarities to past abuse (e.g., pain, undressing, lack of control). However, no prior studies have provided formal qualitative analyses regarding CSA survivors' reactions to cancer treatment. Therefore, our study's objective was to identify key themes pertaining to CSA survivors' cancer treatment experiences...
August 15, 2017: Palliative & Supportive Care
https://www.readbyqxmd.com/read/28803723/perceived-social-support-among-patients-with-burn-injuries-a-perspective-from-the-developing-world
#5
Ahmed Waqas, Marvee Turk, Sadiq Naveed, Atif Amin, Harriet Kiwanuka, Neha Shafique, Muhammad Ashraf Chaudhry
BACKGROUND: Social support is among the most well-established predictors of post-burn psychopathology after burn. Despite a disproportionately large burden of burns in the developing world, the nature of social support among burn patients in this context remains elusive. We, therefore, seek to investigate social support and its biopsychosocial determinants among patients with burn injuries in Pakistan. METHODS: A cross-sectional study of 343 patients presenting with burn injuries at four teaching hospitals in the Punjab province of Pakistan was conducted...
August 10, 2017: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/28801218/urology-residents-experience-and-attitude-towards-surgical-simulation-presenting-our-four-year-experience-with-a-multi-institutional-multi-modality-simulation-model
#6
Alexander Chow, B Sherer, E Yura, S Kielb, E Kocjancic, S Eggener, T Turk, S Park, S Psutka, M Abern, K Latchamsetty, C Coogan
OBJECTIVE: To evaluate the Urological resident's attitude and experience with surgical simulation in residency education using a multi-institutional, multi-modality model. MATERIALS AND METHODS: Residents from six area urology training programs rotated through simulation stations in four consecutive sessions from 2014 to 2017. Workshops included GreenLight photovaporization of the prostate(PVP), ureteroscopic stone extraction, laparoscopic peg transfer, 3-dimensional laparoscopy rope pass, transobturator sling placement, intravesical injection, high definition video system trainer (VITOM), vasectomy, and Urolift...
August 8, 2017: Urology
https://www.readbyqxmd.com/read/28796090/jacobson-s-nerve-schwannoma-presenting-as-a-middle-ear-mass-causing-pulsatile-tinnitus-a-case-report
#7
Kenny F Lin, Andrew T Turk, Ana Hae-Ok Kim
No abstract text is available yet for this article.
August 8, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28765824/is-nonhomogeneous-expression-of-tissue-mast-cells-or-allergen-specific-iges-bound-to-tissue-mast-cells-possible
#8
Murat Türk, Sakine Nazik Bahçecioğlu, İnsu Yılmaz
Skin prick tests (SPTs) are widely used to demonstrate an IgE-mediated hypersensitivity reaction to a specific allergen. However, local allergic conditions cannot be diagnosed with SPTs. Local specific IgE production was only presented before in mucosal tissues. We present a patient with house dust mite sensitization that had variable SPTs results in different body regions.
July 2017: Asia Pacific Allergy
https://www.readbyqxmd.com/read/28763469/end-of-life-care-for-immigrants-in-germany-an-epidemiological-appraisal-of-berlin
#9
Antje Henke, Peter Thuss-Patience, Asita Behzadi, Oliver Henke
BACKGROUND: Since the late 1950's, a steadily increasing immigrant population in Germany is resulting in a subpopulation of aging immigrants. The German health care system needs to adjust its services-linguistically, culturally, and medically-for this subpopulation of patients. Immigrants make up over 20% of the population in Germany, yet the majority receive inadequate medical care. As many of the labor immigrants of the 1960s and 1970s are in need of hospice and palliative care (HPC), little is known about this specialized care for immigrants...
2017: PloS One
https://www.readbyqxmd.com/read/28761580/is-prostate-biopsy-recommended-in-turkish-men-with-a-prostate-specific-antigen-level-between-2-5-and-4-ng-ml
#10
Gokhan Koc, Hakan Turk, Mustafa Karabicak, Sitki Un, Batuhan Ergani, Rahmi Gokhan Ekin
BACKGROUND: Prostate cancer is the most common solid tumor. The incidence of prostate cancer shows regional and racial differences. The ideal PSA threshold for prostate biopsy is still being debated. OBJECTIVE: We aimed to investigate cancer detection rates in Turkish men who underwent transrectal ultrasound-guided prostate biopsy (TRUSPB) who had prostate-specific antigen (PSA) levels in the range of 2.5 to 4.0 ng/mL and compare them with the rates of cancer in patients with PSA levels in the range of 4...
2017: Current Therapeutic Research, Clinical and Experimental
https://www.readbyqxmd.com/read/28760865/dystroglycan-maintains-inner-limiting-membrane-integrity-to-coordinate-retinal-development
#11
Reena Clements, Rolf Turk, Kevin P Campbell, Kevin M Wright
Proper neural circuit formation requires the precise regulation of neuronal migration, axon guidance and dendritic arborization. Mutations affecting the function of the transmembrane glycoprotein dystroglycan cause a form of congenital muscular dystrophy that is frequently associated with neurodevelopmental abnormalities. Despite its importance in brain development, the role for dystroglycan in regulating retinal development remains poorly understood. Using a mouse model of dystroglycanopathy (ISPD(L79*) ) and conditional dystroglycan mutants of both sexes, we show that dystroglycan is critical for the proper migration, axon guidance and dendritic stratification of neurons in the inner retina...
July 31, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28760180/tobacco-marketing-e-cigarette-susceptibility-and-perceptions-among-adults
#12
Nicole E Nicksic, L Morgan Snell, Alyssa K Rudy, Caroline O Cobb, Andrew J Barnes
OBJECTIVE: Understanding the impact of tobacco marketing on e-cigarette (EC) susceptibility and perceptions is essential to inform efforts to mitigate tobacco product burden on public health. METHODS: Data were collected online in 2016 from 634 conventional cigarette (CC) smokers and 393 non-smokers using a convenience sample from Amazon Mechanical Turk. Logistic regression models, stratified by smoking status and adjusted for socio-demographics, examined the relationship among tobacco advertisements and coupons, EC and CC susceptibility, and EC perceptions...
September 1, 2017: American Journal of Health Behavior
https://www.readbyqxmd.com/read/28758990/coordinated-regulation-of-growth-activity-and-transcription-in-natural-populations-of-the-unicellular-nitrogen-fixing-cyanobacterium-crocosphaera
#13
Samuel T Wilson, Frank O Aylward, Francois Ribalet, Benedetto Barone, John R Casey, Paige E Connell, John M Eppley, Sara Ferrón, Jessica N Fitzsimmons, Christopher T Hayes, Anna E Romano, Kendra A Turk-Kubo, Alice Vislova, E Virginia Armbrust, David A Caron, Matthew J Church, Jonathan P Zehr, David M Karl, Edward F DeLong
The temporal dynamics of phytoplankton growth and activity have large impacts on fluxes of matter and energy, yet obtaining in situ metabolic measurements of sufficient resolution for even dominant microorganisms remains a considerable challenge. We performed Lagrangian diel sampling with synoptic measurements of population abundances, dinitrogen (N2) fixation, mortality, productivity, export and transcription in a bloom of Crocosphaera over eight days in the North Pacific Subtropical Gyre (NPSG). Quantitative transcriptomic analyses revealed clear diel oscillations in transcript abundances for 34% of Crocosphaera genes identified, reflecting a systematic progression of gene expression in diverse metabolic pathways...
July 31, 2017: Nature Microbiology
https://www.readbyqxmd.com/read/28750895/genotoxic-evaluation-of-poly-anhydride-nanoparticles-in-the-gastrointestinal-tract-of-mice
#14
T Iglesias, J M Irache, M Butinar, B Turk, A López de Cerain, A Azqueta
Gantrez(®) AN 119-based NPs have been developed as oral drug carriers due to their strong bioadhesive interaction with components of the gastrointestinal mucosa and to their adaptable surface. The use of mannosamine to coat Gantrez(®) AN 119-based NPs results in a high mucus-permeable carrier, able to reach the gastrointestinal epithelium. Although their efficacy to transport a therapeutic agent has been demonstrated, their safety has not yet been thoroughly studied. They have proved to be non-cytotoxic, non-genotoxic and non-mutagenic in vitro; however, the in vivo toxicity profile has not yet been determined...
July 24, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28747442/chemotherapy-induced-peripheral-neuropathy-clinical-trials-review-and-recommendations
#15
REVIEW
Jennifer S Gewandter, Roy Freeman, Rachel A Kitt, Guido Cavaletti, Lynn R Gauthier, Michael P McDermott, Nimish A Mohile, Supriya G Mohlie, A Gordon Smith, Mohamedtaki A Tejani, Dennis C Turk, Robert H Dworkin
OBJECTIVE: To assess the design characteristics and reporting quality of published randomized controlled trials (RCTs) for treatments of chemotherapy-induced peripheral neuropathy (CIPN) initiated before or during chemotherapy. METHODS: In this systematic review of RCTs of preventive or symptomatic pharmacologic treatments for CIPN initiated before or during chemotherapy treatment, articles were identified by updating the PubMed search utilized in the CIPN treatment guidelines published in the Journal of Clinical Oncology in 2014...
July 26, 2017: Neurology
https://www.readbyqxmd.com/read/28746883/comparing-undergraduate-and-community-recruited-adult-non-gamblers-motives-for-not-gambling-do-they-differ
#16
Christina L Rash, Hyoun S Kim, David C Hodgins, Daniel S McGrath
The field of gambling studies has extensively focused on isolating risk factors for developing a gambling disorder. Conversely, little attention has been paid to identifying protective factors against gambling disorder among people who choose to not gamble at all. Moreover, the limited number of studies that have focused on non-gamblers have neglected to differentiate current from lifetime non-gamblers. The purpose of the present study was to examine motives for not gambling among a diverse sample of adult lifetime non-gamblers recruited from the community and to compare these motives to an undergraduate student sample of non-gamblers from a previous study...
July 18, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/28745127/modified-gold-based-sirna-nanotherapeutics-for-targeted-therapy-of-triple-negative-breast-cancer
#17
Reza Shahbazi, Elif Asik, Nermin Kahraman, Mustafa Turk, Bulent Ozpolat, Kezban Ulubayram
AIM: In this study, we aimed to therapeutically target eukaryotic elongation factor 2 kinase (eEF-2K) in an in vivo triple-negative breast cancer (TNBC) tumor model. MATERIALS & METHODS: We synthesized a highly monodisperse nanoformulation using polyethylenimine-modified gold nanoparticles (AuNP-PEI) as siRNA delivery vehicle and evaluated gene downregulation. RESULTS: We found that AuNP-PEI/eEF-2K nanoformulation was highly effective for in vitro and in vivo gene downregulation and showed remarkable antitumor efficacy that was associated with eEF-2K knockdown, inhibition of Src and MAPK-ERK signaling pathways in a TNBC orthotopic tumor model...
July 26, 2017: Nanomedicine
https://www.readbyqxmd.com/read/28743370/computational-and-clinical-investigation-on-the-role-of-mechanical-vibration-on-orthodontic-tooth-movement
#18
Zhipeng Liao, Selma Elekdag-Turk, Tamer Turk, Johnathan Grove, Oyku Dalci, Junning Chen, Keke Zheng, M Ali Darendeliler, Michael Swain, Qing Li
The aim of this study is to investigate the biomechanics for orthodontic tooth movement (OTM) subjected to concurrent single-tooth vibration (50Hz) with conventional orthodontic force application, via a clinical study and computational simulation. Thirteen patients were recruited in the clinical study, which involved distal retraction of maxillary canines with 1.5N (150g) force for 12weeks. In a split mouth study, vibration and non-vibration sides were randomly assigned to each subject. Vibration of 50Hz, of approximately 0...
June 21, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/28738108/prevalence-course-and-associated-factors-of-pain-in-the-temporomandibular-joint-in-early-rheumatoid-arthritis-results-of-a-longitudinal-cohort-study
#19
Jessica P Chin Jen Sem, Marike van der Leeden, Corine M Visscher, Karin Britsemmer, Samina A Turk, Joost Dekker, Dirkjan van Schaardenburg, Frank Lobbezoo
AIMS: To assess the prevalence, 3-year course, and associated factors of temporomandibular joint (TMJ) pain in patients with newly diagnosed rheumatoid arthritis (RA). METHODS: A total of 264 patients with newly diagnosed RA were included. Patients were assessed after 3 months, 6 months, 9 months, 1 year, 1.5 years, 2 years, and 3 years. TMJ pain was scored by manual palpation, and the prevalence of TMJ pain was calculated at baseline and at all seven follow-up intervals during 3 years...
2017: Journal of Oral & Facial Pain and Headache
https://www.readbyqxmd.com/read/28738020/resident-memory-t-cells-in-the-skin-mediate-durable-immunity-to-melanoma
#20
Brian T Malik, Katelyn T Byrne, Jennifer L Vella, Peisheng Zhang, Tamer B Shabaneh, Shannon M Steinberg, Aleksey K Molodtsov, Jacob S Bowers, Christina V Angeles, Chrystal M Paulos, Yina H Huang, Mary Jo Turk
Tissue-resident memory T (TRM) cells have been widely characterized in infectious disease settings; however, their role in mediating immunity to cancer remains unknown. We report that skin-resident memory T cell responses to melanoma are generated naturally as a result of autoimmune vitiligo. Melanoma antigen-specific TRM cells resided predominantly in melanocyte-depleted hair follicles and were maintained without recirculation or replenishment from the lymphoid compartment. These cells expressed CD103, CD69, and CLA (cutaneous lymphocyte antigen), but lacked PD-1 (programmed cell death protein-1) or LAG-3 (lymphocyte activation gene-3), and were capable of making IFN-γ (interferon-γ)...
April 14, 2017: Science Immunology
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