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Unilateral Vocal Fold Paralysis

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https://www.readbyqxmd.com/read/29111336/regenerative-effects-of-basic-fibroblast-growth-factor-on-restoration-of-thyroarytenoid-muscle-atrophy-caused-by-recurrent-laryngeal-nerve-transection
#1
Mami Kaneko, Takuya Tsuji, Yo Kishimoto, Yoichiro Sugiyama, Tatsuo Nakamura, Shigeru Hirano
OBJECTIVES: Vocal fold atrophy following unilateral vocal fold paralysis is caused by atrophy of the thyroarytenoid (TA) muscle and remains a challenge. Medialization procedures are popular treatment options; however, hoarseness often remains due to the reduction in mass or tension of the TA muscle. Therefore, in addition to medialization procedures, TA muscle reinnervation is desirable. In vivo studies have shown the potential for basic fibroblast growth factor (bFGF) to affect muscular and nerve regeneration...
October 27, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/29090002/adipose-derived-mesenchymal-stem-cells-accelerate-nerve-regeneration-and-functional-recovery-in-a-rat-model-of-recurrent-laryngeal-nerve-injury
#2
Yun Li, Wen Xu, Li-Yu Cheng
Medialization thyroplasty or injection laryngoplasty for unilateral vocal fold paralysis cannot restore mobility of the vocal fold. Recent studies have shown that transplantation of mesenchymal stem cells is effective in the repair of nerve injuries. This study investigated whether adipose-derived stem cell transplantation could repair recurrent laryngeal nerve injury. Rat models of recurrent laryngeal nerve injury were established by crushing with micro forceps. Adipose-derived mesenchymal stem cells (ADSCs; 8 × 10(5)) or differentiated Schwann-like adipose-derived mesenchymal stem cells (dADSCs; 8 × 10(5)) or extracellular matrix were injected at the site of injury...
September 2017: Neural Regeneration Research
https://www.readbyqxmd.com/read/29079122/unilateral-vocal-fold-paralysis-in-parkinson-disease-case-report-and-review-of-the-literature
#3
Abdul-Latif Hamdan, Elie Khalifee, Georges Tabet
OBJECTIVE: The objective of this study was to report the first case of unilateral vocal fold paralysis in a patient with Parkinson disease (PD) and to review the literature. METHODS: This is a case report and literature review following PubMed search using the keywords "Parkinson," "vocal fold paralysis," "vocal fold palsy," "vocal fold immobility," "vocal fold adductor palsy," "airway obstruction," and "stridor." RESULTS: A total of 18 subjects diagnosed with PD and vocal fold paralysis were described...
October 24, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/29062449/injection-laryngoplasty-as-miniinvasive-office-based-surgery-in-patients-with-unilateral-vocal-fold-paralysis-voice-quality-outcomes
#4
Ewelina M Sielska-Badurek, Maria Sobol, Katarzyna Jędra, Anna Rzepakowska, Ewa Osuch-Wójcikiewicz, Kazimierz Niemczyk
INTRODUCTION: Injection laryngoplasty (glottis augmentation) is the preferred method in surgical management of unilateral vocal fold paralysis (UVFP). Traditionally, these procedures are performed in the operating room. Nowadays, however, these procedures have moved into the office. AIM: To evaluate the voice quality after transoral injection laryngoplasty under local anaesthesia in patients with unilateral vocal fold paralysis. MATERIAL AND METHODS: Fourteen subjects (5 women and 9 men) with unilateral vocal fold paresis (9 with right vocal fold paresis and 5 with left vocal fold paresis) were included in the study...
September 2017: Wideochirurgia i Inne Techniki Mało Inwazyjne, Videosurgery and Other Miniinvasive Techniques
https://www.readbyqxmd.com/read/28986671/transcervical-fat-injection-laryngoplasty-for-unilateral-vocal-fold-paralysis-an-easy-way-to-do-the-job
#5
Hisham E M Elbadan, Wael K A Hussein, Riham M Elmaghraby
Unilateral vocal fold paralysis resulting in glottic incompetence can cause impairment of laryngeal functions, including airway protection and phonation. The objective of this study is to present an easy new technique for harvesting and injection of abdominal fat into the vocal fold for patients with unilateral vocal fold paralysis. This is a retrospective study of patients carried out on 16 patients suffering from unilateral vocal fold paralysis resulting from different etiologies. All patients were subjected to the protocol of voice assessment pre- and postoperatively...
December 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28965662/correlation-of-the-iranian-voice-quality-of-life-profile-ivqlp-with-acoustic-measurements-across-three-common-voice-disorders
#6
Ali Dehqan, Ronald C Scherer, Fariba Yadegari, Gholamali Dashti
OBJECTIVES: The Iranian Voice Quality of Life Profile (IVQLP) is a recent culture-based developed tool for assessing the quality of life of dysphonic patients. The research questions addressed here are as follows: (1) Are the correlations between IVQLP scores and values of objective voice measures? (2) Do the correlations differ across the three different voice disorders? METHODS: The subjects were divided into three groups: muscle tension dysphonia (MTD) (n = 62), benign midmembranous vocal fold lesions (n = 56), and unilateral vocal fold paralysis (UVFP) (n = 32)...
September 28, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/28965097/does-laryngeal-reinnervation-or-type-i-thyroplasty-give-better-voice-results-for-patients-with-unilateral-vocal-fold-paralysis-vocalist-study-protocol-for-a-feasibility-randomised-controlled-trial
#7
Helen Blackshaw, Paul Carding, Marcus Jepson, Marina Mat Baki, Gareth Ambler, Anne Schilder, Stephen Morris, Aneeka Degun, Rosamund Yu, Samantha Husbands, Helen Knowles, Chloe Walton, Yakubu Karagama, Kate Heathcote, Martin Birchall
INTRODUCTION: A functioning voice is essential for normal human communication. A good voice requires two moving vocal folds; if one fold is paralysed (unilateral vocal fold paralysis (UVFP)) people suffer from a breathy, weak voice that tires easily and is unable to function normally. UVFP can also result in choking and breathlessness. Current treatment for adults with UVFP is speech therapy to stimulate recovery of vocal fold (VF) motion or function and/or injection of the paralysed VF with a material to move it into a more favourable position for the functioning VF to close against...
September 29, 2017: BMJ Open
https://www.readbyqxmd.com/read/28949246/a-case-series-of-the-probability-density-and-cumulative-distribution-of-laryngeal-disease-in-a-tertiary-care-voice-center
#8
Jaime de la Fuente, C Gaelyn Garrett, Robert Ossoff, Kim Vinson, David O Francis, Alexander Gelbard
OBJECTIVE: To examine the distribution of clinic and operative pathology in a tertiary care laryngology practice. METHODS: Probability density and cumulative distribution analyses (Pareto analysis) was used to rank order laryngeal conditions seen in an outpatient tertiary care laryngology practice and those requiring surgical intervention during a 3-year period. RESULTS: Among 3783 new clinic consultations and 1380 operative procedures, voice disorders were the most common primary diagnostic category seen in clinic (n = 3223), followed by airway (n = 374) and swallowing (n = 186) disorders...
November 2017: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/28882539/multidimensional-effects-of-voice-therapy-in-patients-affected-by-unilateral-vocal-fold-paralysis-due-to-cancer
#9
Camila Barbosa Barcelos, Paula Angélica Lorenzon Silveira, Renata Lígia Vieira Guedes, Aline Nogueira Gonçalves, Luciana Dall'Agnol Siqueira Slobodticov, Elisabete Carrara-de Angelis
INTRODUCTION: Patients with unilateral vocal fold paralysis may demonstrate different degrees of voice perturbation depending on the position of the paralyzed vocal fold. Understanding the effectiveness of voice therapy in this population may be an important coefficient to define the therapeutic approach. OBJECTIVE: To evaluate the voice therapy effectiveness in the short, medium and long-term in patients with unilateral vocal fold paralysis and determine the risk factors for voice rehabilitation failure...
August 24, 2017: Brazilian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/28826979/the-3d-printing-of-the-paralyzed-vocal-fold-added-value-in-injection-laryngoplasty
#10
Abdul-Latif Hamdan, Ghassan Haddad, Ali Haydar, Ramsey Hamade
INTRODUCTION: Three-dimensional (3D) printing has had numerous applications in various disciplines, especially otolaryngology. We report the first case of a high-fidelity 3D-printed model of the vocal cords of a patient with unilateral vocal cord paralysis in need of injection laryngoplasty. METHODOLOGY: A case report was carried out. RESULTS: A tailored 3D-printed anatomically precise models for injection laryngoplasty has the potential to enhance preoperative planning, resident teaching, and patient education...
August 18, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/28822413/-diagnostic-value-of-multi-slice-spiral-computerized-tomographic-fistulography-in-congenital-fistula-of-neck
#11
H Zheng, Q Ye, X Y Wang, X H Zheng, X Q Yang, Y Chen, Y Jiang, R Y Li
Objective: To investigate the usefulness and effectiveness of multi-slice spiral computerized tomographic fistulography (MSCTF) in the diagnosis and treatment of congenital fistula of neck. Methods: Thirty-four patients with thyroglossal fistulasor branchial cleft fistulas who were initial treated from July 2008 to August 2015 in Fujian Provincial Hospital were retrospectively analyses. Thirteen males and 21 females patients aging from 3 to 46 years old with a median age of 37 were included. There were thyroglossal fistula in 6 cases, the first branchialcleft fistula in 9 cases, the second branchialcleft fistula in 3 cases, the third branchialcleft fistula in 9 cases, and the fourth branchialcleft fistula in 7 cases...
August 7, 2017: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/28762290/implications-of-synkinesis-in-unilateral-vocal-fold-paralysis
#12
Yu-Cheng Pei, Wei-Han Chang, Hsiu-Feng Chuang, Chia-Fen Chang, Tuan-Jen Fang
Objectives In patients with unilateral vocal fold paralysis (UVFP), laryngeal electromyography (LEMG) occasionally observes synkinesis in laryngeal muscles, a condition that could impair vocal fold mobility and voice control. This study aims to evaluate the impact of synkinesis on UVFP patients. Study Design A retrospective case-control study. Setting Medical center. Subjects and Methods Patients with UVFP onset >6 months were recruited (N = 104). The outcome measurements included LEMG, quantitative LEMG analysis of thyroarytenoid-lateral cricoarytenoid (TA-LCA) muscle complex, glottal gap measured by videolaryngostroboscopy, voice-related quality of life, and voice acoustic analysis...
July 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28740437/the-larynx-ruler-to-measure-height-and-profile-of-vocal-folds-a-proof-of-concept
#13
Gauthier Desuter, Benjamin Mertens, Alain Delchambre, Julie van Lith-Bijl, Peter Paul van Benthem, Elisabeth Sjögren
INTRODUCTION: Glottic leakage during phonation is a direct consequence of unilateral vocal fold (VF) paralysis. This air leakage can be in the horizontal plane and in the vertical plane. Presently, there is no easily applicable medical device allowing noninvasive, office-based measurement of the relative vertical position of the VFs. The larynx ruler (LR) is a laser-based measuring device that could meet the previously stated need, using a flexible endoscope. This study represents a proof of concept regarding the use of the LR in assessing VF relative positions in the vertical plane...
2017: Medical Devices: Evidence and Research
https://www.readbyqxmd.com/read/28739333/comparison-of-two-multiparameter-acoustic-indices-of-dysphonia-severity-the-acoustic-voice-quality-index-and-cepstral-spectral-index-of-dysphonia
#14
Jeong Min Lee, Nelson Roy, Elizabeth Peterson, Ray M Merrill
OBJECTIVES: The Acoustic Voice Quality Index (AVQI) and the Cepstral Spectral Index of Dysphonia (CSID) are two multiparameter acoustic indices designed to objectively estimate dysphonia severity and track treatment outcomes. This study compared the performance of these two indices using a common corpus of dysphonic speakers. METHOD: Pre- and posttreatment samples of sustained vowel and connected speech were elicited from 112 patients across six diagnostic categories: unilateral vocal fold paralysis (n = 12), adductor spasmodic dysphonia (n = 12), primary muscle tension dysphonia (n = 12), benign vocal fold lesions (n = 12), presbylaryngis (n = 12), and mutational falsetto (n = 12)...
July 21, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/28699172/outcomes-of-medialization-laryngoplasty-with-and-without-arytenoid-adduction
#15
Joseph Chang, Sarah L Schneider, James Curtis, Jonelyn Langenstein, Mark S Courey, Katherine C Yung
OBJECTIVES/HYPOTHESIS: To evaluate the effect of medialization laryngoplasty (ML) performed alone compared to ML with arytenoid adduction (AA) on glottic gap and voice quality in unilateral vocal fold paralysis (UVFP) patients. STUDY DESIGN: Retrospective case series. METHODS: UVFP patients treated with ML alone and ML with AA at the University of California San Francisco Voice and Swallowing Center were identified. Demographic information and history of laryngeal procedures were collected...
November 2017: Laryngoscope
https://www.readbyqxmd.com/read/28684786/autologous-thyroid-cartilage-graft-implantation-in-medialization-laryngoplasty-a-modified-approach-for-treating-unilateral-vocal-fold-paralysis
#16
Ming-Shao Tsai, Ming-Yu Yang, Geng-He Chang, Yao-Te Tsai, Meng-Hung Lin, Cheng-Ming Hsu
Medialization laryngoplasty is the standard surgical treatment for unilateral vocal fold paralysis. This study presents a modified approach in which a thyroid cartilage graft is implanted in medialization laryngoplasty. 22 patients who underwent this approach were included in the study. The results revealed that glottal incompetence and vocal performance were markedly improved following surgery, and the follow-up period ranged from 6 to 74 months (mean, 21.4 months). Acoustic analysis revealed significant improvements in the maximum phonation time (from 3...
July 6, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28684252/medialization-laryngoplasty-after-injection-augmentation
#17
Valeria Silva Merea, Solomon Husain, Lucian Sulica
OBJECTIVES: This study aims to assess the effect of vocal fold injection augmentation (IA) on subsequent medialization laryngoplasty (ML). STUDY DESIGN: A retrospective cohort study with follow-up telephone survey was carried out. METHODS: Clinical records of patients with unilateral vocal fold paralysis or paresis (VFP) who underwent ML between April 2006 and March 2015 were reviewed. Patients who underwent IA before ML were compared with patients who did not, with respect to demographic information, symptoms, Voice Handicap Index-10 (VHI-10), etiology of VFP, and revision rate...
July 3, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/28636732/positron-emission-tomography-enhancement-after-vocal-fold-injection-medialization
#18
Nazaneen Grant, Richard J Wong, Dennis H Kraus, Heiko Schoder, Ryan C Branski
The potential for the misinterpretation of positron-emission tomography (PET) scans in the context of a possible malignancy has been confirmed in a case report showing increased 18F-fluorodeoxyglucose (FDG) uptake after unilateral vocal fold augmentation medialization. We sought to expand these findings by investigating FDG uptake in a larger cohort of patients via a retrospective chart review. We examined the records of 15 adults-8 men and 7 women-who had undergone vocal fold augmentation for unilateral vocal fold paralysis and at least one subsequent PET scan...
June 2017: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/28612098/measurement-of-the-maximum-frequency-of-electroglottographic-fluctuations-in-the-expiration-phase-of-volitional-cough-as-a-functional-test-for-cough-efficiency
#19
Toshihiko Iwahashi, Makoto Ogawa, Kiyohito Hosokawa, Chieri Kato, Hidenori Inohara
The hypotheses of the present study were that the maximum frequency of fluctuation of electroglottographic (EGG) signals in the expiration phase of volitional cough (VC) reflects the cough efficiency and that this EGG parameter is affected by impaired laryngeal closure, expiratory effort strength, and gender. For 20 normal healthy adults and 20 patients diagnosed with unilateral vocal fold paralysis (UVFP), each participant was fitted with EGG electrodes on the neck, had a transnasal laryngo-fiberscope inserted, and was asked to perform weak/strong VC tasks while EGG signals and a high-speed digital image of the larynx were recorded...
June 13, 2017: Dysphagia
https://www.readbyqxmd.com/read/28608475/the-natural-history-of-recoverable-vocal-fold-paralysis-implications-for-kinetics-of-reinnervation
#20
Ted Mau, Hao-Min Pan, Lesley F Childs
OBJECTIVES/HYPOTHESIS: Patients with unilateral vocal fold paralysis (UVFP) are commonly told to wait 12 months for spontaneous recovery. This study aims to 1) determine the time to vocal recovery in UVFP, 2) use that data to develop a neurophysiologically plausible model for recovery, and 3) use the model to generate meaningful predictions for patient counseling. STUDY DESIGN: Case series with de novo mathematical modeling. METHODS: Patients with UVFP who could pinpoint a discrete onset of vocal improvement were identified...
November 2017: Laryngoscope
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