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Chronic flexibility

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https://www.readbyqxmd.com/read/28538215/the-use-of-polyvinyl-alcohol-sponge-and-cyanoacrylate-glue-in-the-treatment-of-large-and-chronic-bronchopleural-fistulae-following-lung-cancer-resection
#1
Paolo Battistoni, Umberto Caterino, Sandro Batzella, Raffaele Dello Iacono, Gabriele Lucantoni, Giovanni Galluccio
BACKGROUND: Bronchopleural fistulae represent a relatively rare complication of pulmonary resection. For inoperable patients, several endoscopic procedures have been described. In the presence of large and chronic bronchopleural fistulae, persistent air leaks require a surgical therapy, while endoscopic airway stent represents a useful palliative treatment. OBJECTIVE: We describe the successful closure of large and chronic bronchopleural fistulae using an expandable polyvinyl alcohol (PVA) sponge and cyanoacrylate glue...
January 25, 2017: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/28534860/hemophilia-care-in-the-pediatric-age
#2
REVIEW
Marta Bertamino, Francesca Riccardi, Laura Banov, Johanna Svahn, Angelo Claudio Molinari
Hemophilia is the most common of the severe bleeding disorders and if not properly managed since early infancy can lead to chronic disease and lifelong disabilities. However, it enjoys the most efficacious and safe treatment among the most prevalent monogenic disorders. Hemophilia should be considered in the neonatal period in the case of unusual bleeding or in the case of positive family history. Later, hemophilia should be suspected mainly in males because of abnormal bruising/bleeding or unusual bleeding following invasive procedures-for example, tonsillectomy or circumcision...
May 19, 2017: Journal of Clinical Medicine
https://www.readbyqxmd.com/read/28533619/the-effects-of-exercise-using-an-ergometer-with-swaying-saddle-on-chronic-lower-back-pain
#3
Seung Jin Byeon, Ki Hyun Kim
[Purpose] This study aims to investigate the effects of exercise using an ergometer with swaying saddle on chronic lower back pain. [Subjects and Methods] Thirty-three normal adults (university students) with chronic lower back pain were randomly recruited. The flexibility and strength of muscles were measured before and after an 8-week intervention. Belly-bike, an ergometer with a swaying saddle, was used. The duration of intervention was 30 minutes a day, 3 times a week. To measure the level of pain, visual analogue scale (VAS) and Korean Oswestry Disability Index were used...
April 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28533392/syringe-injectable-mesh-electronics-integrate-seamlessly-with-minimal-chronic-immune-response-in-the-brain
#4
Tao Zhou, Guosong Hong, Tian-Ming Fu, Xiao Yang, Thomas G Schuhmann, Robert D Viveros, Charles M Lieber
Implantation of electrical probes into the brain has been central to both neuroscience research and biomedical applications, although conventional probes induce gliosis in surrounding tissue. We recently reported ultraflexible open mesh electronics implanted into rodent brains by syringe injection that exhibit promising chronic tissue response and recording stability. Here we report time-dependent histology studies of the mesh electronics/brain-tissue interface obtained from sections perpendicular and parallel to probe long axis, as well as studies of conventional flexible thin-film probes...
May 22, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28527424/influence-of-chronic-stretching-on-muscle-performance-systematic-review
#5
D M Medeiros, C S Lima
The aim of the current study was to investigate the influence of chronic stretching on muscle performance (MP) by a systematic review. The search strategy included MEDLINE, PEDro, Cochrane CENTRAL, LILACS, and manual search from inception to June 2016. Randomized and controlled clinical trials, non-randomized, and single group studies that have analyzed the influence of flexibility training (FT) (using any stretching technique) on MP were included. Differently, studies with special populations (children, elderly, and people with any dysfunction/disease), and articles that have used FT protocols shorter than three weeks or 12 sessions were excluded...
May 17, 2017: Human Movement Science
https://www.readbyqxmd.com/read/28521247/cognitive-performance-of-juvenile-monkeys-after-chronic-fluoxetine-treatment
#6
Mari S Golub, Edward P Hackett, Casey E Hogrefe, Csaba Leranth, John D Elsworth, Robert H Roth
Potential long term effects on brain development are a concern when drugs are used to treat depression and anxiety in childhood. In this study, male juvenile rhesus monkeys (three-four years of age) were dosed with fluoxetine or vehicle (N=16/group) for two years. Histomorphometric examination of cortical dendritic spines conducted after euthanasia at one year postdosing (N=8/group) suggested a trend toward greater dendritic spine synapse density in prefrontal cortex of the fluoxetine-treated monkeys. During dosing, subjects were trained for automated cognitive testing, and evaluated with a test of sustained attention...
May 1, 2017: Developmental Cognitive Neuroscience
https://www.readbyqxmd.com/read/28516401/endovascular-crossing-of-chronic-total-occlusions-using-an-impulse-an-explorative-design-study
#7
Aimée Sakes, Marleen van der Wiel, Dimitra Dodou, Paul Breedveld
In this study we investigated whether exerting an impulse on a Chronic Total Occlusion (CTO) improves the success rate of CTO crossing as compared to the currently used method of statically pushing the guidewire against the CTO. A prototype (Ø2 mm) was developed that generates translational momentum using a spring-loaded indenter and converts it to an impulse during impact. Mechanical performance was evaluated by measuring the peak force and momentum for different spring compressions and strike distances in air and blood-mimicking fluid...
May 17, 2017: Cardiovascular Engineering and Technology
https://www.readbyqxmd.com/read/28515414/mediastinal-solitary-fibrous-tumor-diagnosed-by-endobronchial-ultrasound-directed-biopsy
#8
Alaina J Webb, Ahmed S Yassin, Ali Saeed, Hemang Yadav, James P Utz
BACKGROUND Solitary fibrous tumors of the middle mediastinal space are uncommon and often not discovered until symptoms secondary to compression of adjacent structures occur. Diagnosis requires surgical biopsy and histological tissue analysis. We describe the ECHO appearance of the solitary fibrous tumor and successful non-invasive EBUS diagnosis. This method of diagnosis allowed for surgical planning for resection and allowed us to exclude non-surgical diseases, such as small cell carcinoma. CASE REPORT A 32-year-old man presented to his primary care physician with worsening intermittent chronic chest pain with recent progressive dysphagia, cough, and dyspnea...
May 18, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/28503533/effect-of-core-strengthening-with-pelvic-proprioceptive-neuromuscular-facilitation-on-trunk-balance-gait-and-function-in-chronic-stroke
#9
Vishal Sharma, Jaskirat Kaur
The purpose of this study was to evaluate the effects of core strengthening combined with pelvic proprioceptive neuromuscular facilitation (PNF) on trunk impairment, balance, gait, and functional ability of chronic stroke patients. Twenty-three participants with chronic stroke were recruited and randomly allocated to one of the two groups: core strengthening combined with pelvic PNF (group 1, n=13), and pelvic PNF with trunk flexibility exercises (group 2, n=10). Intervention was given to both groups for 60 min per session 5 times per week for 4 weeks...
April 2017: Journal of Exercise Rehabilitation
https://www.readbyqxmd.com/read/28501341/chronic-boutonniere-deformity-cross-lateral-band-technique-using-palmaris-longus-autograft
#10
Serdar Duzgun, Alpay Duran, Ekrem Keskin, Ahmet K Yigit, Hasan Buyukdogan
PURPOSE: The purpose of this study was to evaluate the outcomes of treatment of chronic boutonniere deformity with a reconstruction technique using palmaris longus autograft. MATERIALS AND METHODS: Seven patients with chronic, posttraumatic, flexible boutonniere deformities referred to our clinic between January 2010 and September 2014 were included in the study. In all 7 patients, the lateral bands were deficient or damaged beyond repair. A novel reconstruction technique for chronic boutonniere deformity utilizing palmaris longus autograft was used...
May 11, 2017: Journal of Hand Surgery
https://www.readbyqxmd.com/read/28499100/probing-for-neuroadaptations-to-unpredictable-stressors-in-addiction-translational-methods-and-emerging-evidence
#11
Jesse T Kaye, Daniel E Bradford, Katherine P Magruder, John J Curtin
Stressors clearly contribute to addiction etiology and relapse in humans, but our understanding of specific mechanisms remains limited. Rodent models of addiction offer the power, flexibility, and precision necessary to delineate the causal role and specific mechanisms through which stressors influence alcohol and other drug use. This review describes a program of research using startle potentiation to unpredictable stressors that is well positioned to translate between animal models and clinical research with humans on stress neuroadaptations in addiction...
May 2017: Journal of Studies on Alcohol and Drugs
https://www.readbyqxmd.com/read/28493732/psychological-flexibility-mitigates-effects-of-ptsd-symptoms-and-negative-urgency-on-aggressive-behavior-in-trauma-exposed-veterans
#12
Sunny J Dutra, Naomi Sadeh
Recent literature suggests that posttraumatic stress disorder (PTSD) symptoms can interact with personality factors to predict externalizing behaviors. Engagement in externalizing behaviors such as substance abuse and aggressive behavior may, in turn, increase risk for further trauma exposure and a more chronic course of PTSD. In order to better understand how to intervene on this cycle, the current study aimed to identify factors that could explain risk for externalizing behaviors among trauma-exposed veterans...
May 11, 2017: Personality Disorders
https://www.readbyqxmd.com/read/28488190/computational-dissection-of-allosteric-inhibition-of-the-sh2-domain-of-bcr-abl-kinase-by-the-monobody-inhibitor-as25
#13
Mingfei Ji, Guodong Zheng, Xiaolong Li, Zhongqin Zhang, Guanqun Jv, Xiaowei Wang, Jialin Wang
The deregulated breakpoint cluster region (Bcr)-Abelson tyrosine kinase (Abl) fusion protein represents an attractive pharmacological target for the treatment of chronic myeloid leukemia (CML). The high affinity of monobody AS25 was designed to target the Src homology 2 (SH2) domain of Bcr-Abl, leading to allosteric inhibition of Bcr-Abl through formation of protein-protein interactions. An I164E mutation in the SH2 domain disrupts AS25 binding to the SH2 domain of Bcr-Abl. The detailed mechanisms, however, remain to be unresolved...
June 2017: Journal of Molecular Modeling
https://www.readbyqxmd.com/read/28483271/-mindful-neuropsychology-mindfulness-based-cognitive-remediation
#14
E Bulzacka, S Lavault, A Pelissolo, C Bagnis Isnard
OBJECTIVES: Mindfulness based interventions (MBI) have recently gained much interest in western medicine. MBSR paradigm is based on teaching participants to pay complete attention to the present experience and act nonjudgmentally towards stressful events. During this mental practice the meditator focuses his or her attention on the sensations of the body. While the distractions (mental images, thoughts, emotional or somatic states) arise the participant is taught to acknowledge discursive thoughts and cultivate the state of awareness without immediate reaction...
May 5, 2017: L'Encéphale
https://www.readbyqxmd.com/read/28481893/evaluation-of-a-transdiagnostic-psychodynamic-online-intervention-to-support-return-to-work-a-randomized-controlled-trial
#15
Rüdiger Zwerenz, Jan Becker, Katharina Gerzymisch, Martin Siepmann, Martin Holme, Ulrich Kiwus, Sieglinde Spörl-Dönch, Manfred E Beutel
OBJECTIVES: Given their flexibility, online interventions may be useful as an outpatient treatment option to support vocational reintegration after inpatient rehabilitation. To that purpose we devised a transdiagnostic psychodynamic online intervention to facilitate return to work, focusing on interpersonal conflicts at the workplace often responsible for work-related stress. RESEARCH DESIGN AND METHODS: In a randomized controlled trial, we included employed patients from cardiologic, psychosomatic and orthopedic rehabilitation with work-related stress or need for support at intake to inpatient rehabilitation after they had given written consent to take part in the study...
2017: PloS One
https://www.readbyqxmd.com/read/28481144/patients-perspectives-on-care-management-services-for-complex-substance-use-disorders
#16
Eric Hawkins, Aline Lott, Carol Malte, Anissa Frank, Brittney Hamilton, George Sayre, Janelle Painter, John Baer
BACKGROUND: Although care management approaches have potential to improve clinical outcomes and reduce high health care costs of patients with complex substance use disorders, characterized by high psychosocial, psychological and/or medical needs and high acute healthcare utilization, little is known about patients' perspectives or experiences with these interventions. AIMS: To identify barriers and facilitators to patient engagement in care management services for complex substance use disorders from patients' perspectives...
May 8, 2017: Journal of Addictive Diseases
https://www.readbyqxmd.com/read/28474959/is-a-multidisciplinary-aerodigestive-clinic-more-effective-at-treating-recalcitrant-aerodigestive-complaints-than-a-single-specialist
#17
Janine M Rotsides, Gina M Krakovsky, Dinesh K Pillai, Sona Sehgal, Maura E Collins, Carolyn E Noelke, Nancy M Bauman
OBJECTIVE: To determine the utility of a pediatric multidisciplinary aerodigestive clinic (ADC) in treating recalcitrant aerodigestive conditions. METHODS: Longitudinal observational study of presenting complaints, evaluation, management, and outcome of patients seen during 12 monthly ADCs beginning August 2013. RESULTS: Fifty-five patients were seen by the ADC team (otolaryngology/gastroenterology/pulmonology/speech pathology/nurse practitioner) and followed for a mean 17...
May 1, 2017: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/28474657/tracheal-stenting-under-flexible-bronchoscopy-for-large-tracheoesophageal-malignant-lymphadenopathy
#18
Irfan Ismail Ayub, Kalaichelvi Kannan, R Dhenesh, Anand Thiagarajan
A 67-year-old man with poorly controlled chronic obstructive pulmonary disease presented with progressive dysphagia and was diagnosed with locally advanced carcinoma of the esophagus. Positron emission tomography-computed tomography staging showed mediastinal lymphadenopathy including a large lymph node in the tracheoesophageal groove with moderate tracheal compression. He was advised chemoradiotherapy but was reluctant to proceed with the same. He developed stridor 2 months later and repeat imaging showed increased size of the tracheoesophageal lymph node with critical airway narrowing...
May 2017: Lung India: Official Organ of Indian Chest Society
https://www.readbyqxmd.com/read/28470152/histological-evaluation-of-flexible-neural-implants-flexibility-limit-for-reducing-the-tissue-response
#19
Heui Chang Lee, Fredrik Ejserholm, Janak Gaire, Seth Currlin, Jens Schouenborg, Lars Wallman, Martin Bengtsson, Kinam Park, Kevin J Otto
OBJECTIVE: Flexible neural probes are hypothesized to reduce the chronic foreign body response (FBR) mainly by reducing the strain-stress caused by an interplay between the tethered probe and the brain's micromotion. However, a large discrepancy of Young's modulus still exists (3-6 orders of magnitude) between the flexible probes and the brain tissue. This raises the question of whether we need to bridge this gap; would increasing the probe flexibility proportionally reduce the FBR? APPROACH: Using novel off-stoichiometry thiol-enes-epoxy (OSTE+) polymer probes developed in our previous work, we quantitatively evaluated the FBR to four types of probes with different softness: silicon (~150 GPa), polyimide (1...
May 4, 2017: Journal of Neural Engineering
https://www.readbyqxmd.com/read/28468612/the-barriers-and-facilitators-that-indigenous-health-workers-experience-in-their-workplace-and-communities-in-providing-self-management-support-a-multiple-case-study
#20
Jessica Conway, George Tsourtos, Sharon Lawn
BACKGROUND: The inequality in health outcomes between Indigenous (Throughout the paper, the term Indigenous will be used to represent both Aboriginal Australians and Torres Strait Islander Australians.) and non-Indigenous Australians continues to be a major public health issue. Chronic conditions are responsible for the majority of the gap in life expectancy for this population. Evidence suggests that chronic condition management models focusing on self-management have led to improved health outcomes in Indigenous populations...
May 3, 2017: BMC Health Services Research
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