Songhua Cai, Youjun Deng, Zhe Wang, Junyu Zhu, Chujian Huang, Longde Du, Chunguang Wang, Xiangyang Yu, Wenyi Liu, Chenglin Yang, Zhe Wang, Lixu Wang, Kai Ma, Rui Huang, Xiaoyu Zhou, Heng Zou, Wenchong Zhang, Yan Huang, Zhi Li, Tiaoping Qin, Tao Xu, Xiaotong Guo, Zhentao Yu
BACKGROUND: Although many CTC isolation and detection methods can provide information on cancer cell counts, downstream gene and protein analysis remain incomplete. Therefore, it is crucial to develop a technology that can provide comprehensive information on both the number and profile of CTC. METHODS: In this study, we developed a novel microfluidics-based CTC separation and enrichment platform that provided detailed information about CTC. RESULTS: This platform exhibits exceptional functionality, achieving high rates of CTC recovery (87...
2023: Frontiers in Oncology