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https://www.readbyqxmd.com/read/29673146/predictors-of-response-to-ketamine-in-treatment-resistant-major-depressive-disorder-and-bipolar-disorder
#1
Carola Rong, Caroline Park, Joshua D Rosenblat, Mehala Subramaniapillai, Hannah Zuckerman, Dominika Fus, Yena L Lee, Zihang Pan, Elisa Brietzke, Rodrigo B Mansur, Danielle S Cha, Leanna M W Lui, Roger S McIntyre
OBJECTIVES: Extant evidence indicates that ketamine exerts rapid antidepressant effects in treatment-resistant depressive (TRD) symptoms as a part of major depressive disorder (MDD) and bipolar disorder (BD). The identification of depressed sub-populations that are more likely to benefit from ketamine treatment remains a priority. In keeping with this view, the present narrative review aims to identify the pretreatment predictors of response to ketamine in TRD as part of MDD and BD. METHOD: Electronic search engines PubMed/MEDLINE, ClinicalTrials...
April 17, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29672568/rna-seq-transcriptome-analysis-of-amaranthus-palmeri-with-differential-tolerance-to-glufosinate-herbicide
#2
Reiofeli A Salas-Perez, Christopher A Saski, Rooksana E Noorai, Subodh K Srivastava, Amy L Lawton-Rauh, Robert L Nichols, Nilda Roma-Burgos
Amaranthus palmeri (Amaranthaceae) is a noxious weed in several agroecosystems and in some cases seriously threatens the sustainability of crop production in North America. Glyphosate-resistant Amaranthus species are widespread, prompting the use of alternatives to glyphosate such as glufosinate, in conjunction with glufosinate-resistant crop cultivars, to help control glyphosate-resistant weeds. An experiment was conducted to analyze the transcriptome of A. palmeri plants that survived exposure to 0.55 kg ha-1 glufosinate...
2018: PloS One
https://www.readbyqxmd.com/read/29670585/maldi-spectra-database-for-rapid-discrimination-and-subtyping-of-mycobacterium-kansasii
#3
Jayaseelan Murugaiyan, Astrid Lewin, Elisabeth Kamal, Zofia Bakuła, Jakko van Ingen, Vit Ulmann, Miren J Unzaga Barañano, Joanna Humięcka, Aleksandra Safianowska, Uwe H Roesler, Tomasz Jagielski
Mycobacterium kansasii is an emerging non-tuberculous mycobacterial (NTM) pathogen capable of causing severe lung disease. Of the seven currently recognized M. kansasii genotypes (I-VII), genotypes I and II are most prevalent and have been associated with human disease, whereas the other five (III-VII) genotypes are predominantly of environmental origin and are believed to be non-pathogenic. Subtyping of M. kansasii serves as a valuable tool to guide clinicians in pursuing diagnosis and to initiate the proper timely treatment...
2018: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29657402/identification-and-antibiogram-pattern-of-bacillus-cereus-from-the-milk-and-milk-products-in-and-around-jammu-region
#4
Umar Yusuf, S K Kotwal, Sanjolly Gupta, Touqeer Ahmed
Aim: The aims of the present study were to assess the prevalence, identification, and antibiogram pattern of Bacillus cereus from 215 samples of different milk and milk products in and around Jammu region. Materials and Methods: In the present study, 215 samples of milk, rasgulla, burfi, rasmalai, kalaari, paneer, ice cream, and pastry were collected and analyzed for the isolation of the B. cereus using PEMBA, and antibiogram pattern was observed for all the milk and milk products...
February 2018: Veterinary World
https://www.readbyqxmd.com/read/29656124/development-of-an-improved-rapid-bacpro%C3%A2-protocol-and-a-method-for-direct-identification-from-blood-culture-positive-bottles-using-matrix-assisted-laser-desorption-ionization-time-of-flight-mass-spectrometry
#5
Takatoshi Yonezawa, Tomohisa Watari, Kazuho Ashizawa, Daisuke Hanada, Takako Yanagiya, Naoki Watanabe, Takashi Terada, Yutaka Tomoda, Satoshi Fujii
Matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) has been incorporated into pathogenic bacterial identification methods and has improved their rapidity. Various methods have been reported to directly identify bacteria with MALDI-TOF MS by pretreating culture medium in blood culture bottles. Rapid BACpro® (Nittobo Medical Co., Ltd.) is a pretreatment kit for effective collection of bacteria with cationic copolymers. However, the Rapid BACpro® pretreatment kit is adapted only for MALDI Biotyper (Bruker Daltonics K...
April 12, 2018: Journal of Microbiological Methods
https://www.readbyqxmd.com/read/29642927/streptococcus-bovis-unusual-etiology-of-meningitis-in-a-neonate-with-down-syndrome-a-case-report
#6
Sachith Mettananda, Phirarthana Kamalanathan, K Dhananja Namalie
BACKGROUND: Common etiological agents of neonatal meningitis include group B Streptococcus, Escherichia coli, and Staphylococcus aureus. Here we report a rare pathogen - Streptococcus bovis - causing meningitis in a premature neonate with Down syndrome. CASE PRESENTATION: A 26-day-old Asian male neonate with Down syndrome presented with a history of high-grade fever, poor sucking, poor cry, and reduced activity. On admission, he was febrile and had features of circulatory collapse...
April 12, 2018: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/29627394/brucella-melitensis-and-b-abortus-in-eggs-larvae-and-engorged-females-of-dermacentor-marginatus
#7
Qian Wang, Shanshan Zhao, Hazi Wureli, Songsong Xie, Chuangfu Chen, Qingqing Wei, Buyun Cui, Changchun Tu, Yuanzhi Wang
Brucellosis is a relatively common zoonosis, particularly in the developing countries. Our aim was to cultivate the Brucella wild-type strain from eggs of Dermacentor marginatus, and to molecularly investigate the presence of Brucella DNA in different developmental stages. A total of 350 engorged adult female ticks were collected from sheep and cattle, and individually placed into a single clean breathable tube suitable for laying eggs and for the development of larvae. Detection of Brucella DNA was attempted in engorged female ticks and their offsprings based on the Brucella outer membrane protein gene 22 (omp22) and IS711 gene...
March 26, 2018: Ticks and Tick-borne Diseases
https://www.readbyqxmd.com/read/29626994/investigation-of-glyphosate-resistance-levels-and-target-site-based-resistance-tsr-mechanisms-in-conyza-canadensis-l-from-apple-orchards-around-areas-of-bohai-seas-and-loess-plateau-in-china
#8
Yu Mei, Yufang Xu, Shipeng Wang, Lihong Qiu, Mingqi Zheng
The resistance levels to glyphosate and target-site based resistance mechanisms in susceptible (S) and resistant (R) Conyza canadensis (L.) populations, which were collected from apple orchards around areas of Bohai seas and Loess Plateau in China, were investigated. Among forty C. canadensis populations, eighteen populations (45%) were still susceptible; fourteen populations (35%) evolved low resistance levels resistance to glyphosate with resistance index (RI) of 2.02 to 3.90. In contrast, eight populations (20%) evolved medium resistance levels with RI of 4...
April 2018: Pesticide Biochemistry and Physiology
https://www.readbyqxmd.com/read/29626989/quinclorac-resistance-induced-by-the-suppression-of-the-expression-of-1-aminocyclopropane-1-carboxylic-acid-acc-synthase-and-acc-oxidase-genes-in-echinochloa-crus-galli-var-zelayensis
#9
Yuan Gao, Jun Li, Xukun Pan, Dingrong Liu, Richard Napier, Liyao Dong
We previously reported that the mechanism of quinclorac resistance in Echinochloa crus-galli var. zelayensis may be closely related to ethylene biosynthesis and the detoxification of cyanide. Differences in EcCAS gene sequences and expression levels may result in higher capacity to detoxify cyanide in resistant biotypes, which may avoid cyanide accumulation and avoid more ethylene and cyanide production and then avoid damage. In the present study, we focused on the mechanism of resistance related to ethylene biosynthesis in E...
April 2018: Pesticide Biochemistry and Physiology
https://www.readbyqxmd.com/read/29596492/the-prevalence-of-yersinia-enterocolitica-in-game-animals-in-poland
#10
Kinga Syczyło, Aleksandra Platt-Samoraj, Agata Bancerz-Kisiel, Anna Szczerba-Turek, Joanna Pajdak-Czaus, Sebastian Łabuć, Zbigniew Procajło, Piotr Socha, Gulzhan Chuzhebayeva, Wojciech Szweda
Natural reservoirs of Yersinia (Y.) enterocolitica comprise different animal species, but little is known about the role of wild animals in the epidemiology of yersiniosis. The aim of the study was to evaluate the prevalence of Y. enterocolitica among game animals in Poland. The bio-serotypes and the pathogenicity markers of the analyzed isolates were determined. The experimental material comprised rectal swabs from 857 free-living animals hunter-harvested over a period of 2 years (2013-2014) in hunting districts across Poland...
2018: PloS One
https://www.readbyqxmd.com/read/29575495/wheat-streak-mosaic-virus-a-century-old-virus-with-rising-importance-worldwide
#11
REVIEW
Khushwant Singh, Stephen N Wegulo, Anna Skoracka, Jiban Kumar Kundu
Wheat streak mosaic virus (WSMV) causes wheat streak mosaic, a disease of cereals and grasses that threatens wheat production worldwide. It is a monopartite, positive-sense single stranded RNA virus and the type member of the genus Tritimovirus in the family Potyviridae. The only known vector is the wheat curl mite (WCM, Aceria tosichella), recently identified as a species complex of biotypes differing in virus transmission. Low rates of seed transmission have been reported. Infected plants are stunted and have a yellow mosaic of parallel discontinuous streaks on the leaves...
March 25, 2018: Molecular Plant Pathology
https://www.readbyqxmd.com/read/29571586/personalized-transcranial-magnetic-stimulation-in-psychiatry
#12
REVIEW
Luca Cocchi, Andrew Zalesky
Transcranial magnetic stimulation (TMS) is a noninvasive brain stimulation technique that allows for modulating the activity of local neural populations and related neural networks. TMS is touted as a viable intervention to normalize brain activity and alleviate some psychiatric symptoms. However, TMS interventions are known to be only moderately reliable, and the efficacy of such therapies remains to be proven for psychiatric disorders other than depression. We review new opportunities to personalize TMS interventions using neuroimaging and computational modeling, aiming to optimize treatment to suit particular individuals and clinical subgroups...
March 20, 2018: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
https://www.readbyqxmd.com/read/29563899/design-and-construction-of-vibrio-cholerae-strains-that-harbor-various-ctx-prophage-arrays
#13
Hyun J Yu, Da S R Cha, Dong-Hun Shin, Gopinath B Nair, Eun J Kim, Dong W Kim
Toxigenic Vibrio cholerae strains arise upon infection and integration of the lysogenic cholera toxin phage, the CTX phage, into bacterial chromosomes. The V. cholerae serogroup O1 strains identified to date can be broadly categorized into three main groups: the classical biotype strains, which harbor CTX-cla; the prototype El Tor strains (Wave 1 strains), which harbor CTX-1; and the atypical El Tor strains, which harbor CTX-2 (Wave 2 strains) or CTX-3~6 (Wave 3 strains). The efficiencies of replication and transmission of CTX phages are similar, suggesting the possibility of existence of more diverse bacterial strains harboring various CTX phages and their arrays in nature...
2018: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29545778/phenotypic-and-genotypic-characterization-of-klebsiella-pneumoniae-isolated-from-retail-foods-in-china
#14
Shuhong Zhang, Guangzhu Yang, Qinghua Ye, Qingping Wu, Jumei Zhang, Yuanbin Huang
Klebsiella pneumoniae is not only a major hospital-acquired pathogen but also an important food-borne pathogen that can cause septicaemia, liver abscesses, and diarrhea in humans. The phenotypic and genotypic characteristics of K. pneumoniae in retail foods have not been thoroughly investigated in China. The objective of this study was to characterize K. pneumoniae isolates through biotyping, serotyping, determination of virulence factors, antibiotic resistance testing, enterobacterial repetitive intergenic consensus-polymerase chain reaction (ERIC-PCR), and (GTG)5 -PCR molecular typing...
2018: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29545163/validation-of-a-for-anaerobic-bacteria-optimized-maldi-tof-ms-biotyper-database-the-enria-project
#15
A C M Veloo, H Jean-Pierre, U S Justesen, T Morris, E Urban, I Wybo, M Kostrzewa, A W Friedrich
Within the ENRIA project, several 'expertise laboratories' collaborated in order to optimize the identification of clinical anaerobic isolates by using a widely available platform, the Biotyper Matrix Assisted Laser Desorption Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF MS). Main Spectral Profiles (MSPs) of well characterized anaerobic strains were added to one of the latest updates of the Biotyper database db6903; (V6 database) for common use. MSPs of anaerobic strains nominated for addition to the Biotyper database are included in this validation...
March 12, 2018: Anaerobe
https://www.readbyqxmd.com/read/29535137/-lnckdm2b-controls-self-renewal-of-embryonic-stem-cells-via-activating-expression-of-transcription-factor-zbtb3
#16
Buqing Ye, Benyu Liu, Liuliu Yang, Xiaoxiao Zhu, Dongdong Zhang, Wei Wu, Pingping Zhu, Yanying Wang, Shuo Wang, Pengyan Xia, Ying Du, Shu Meng, Guanling Huang, Jiayi Wu, Runsheng Chen, Yong Tian, Zusen Fan
Divergent long noncoding RNAs (lncRNAs) represent a major lncRNA biotype in mouse and human genomes. The biological and molecular functions of the divergent lncRNAs remain largely unknown. Here, we show that lncKdm2b , a divergent lncRNA for Kdm2b gene, is conserved among five mammalian species and highly expressed in embryonic stem cells (ESCs) and early embryos. LncKdm2b knockout impairs ESC self-renewal and causes early embryonic lethality. LncKdm2b can activate Zbtb3 by promoting the assembly and ATPase activity of Snf2-related CREBBP activator protein (SRCAP) complex in trans Zbtb3 potentiates the ESC self-renewal in a Nanog-dependent manner...
March 13, 2018: EMBO Journal
https://www.readbyqxmd.com/read/29534849/capsular-serotyping-of-haemophilus-influenzae-by-using-matrix-associated-laser-desorption-ionization-time-of-flight-mass-spectrometry
#17
Noriko Takeuchi, Shunsuke Segawa, Naruhiko Ishiwada, Misako Ohkusu, Sachio Tsuchida, Mamoru Satoh, Kazuyuki Matsushita, Fumio Nomura
Haemophilus influenzae is a major pathogenic bacteria causing invasive disease, which is classified into six capsular serotypes (a-f) and non-typeable (NT) strains. Capsular serotyping of H. influenzae is traditionally determined by serological methods and more recently by PCR methods. However, these methods are time-consuming and expensive. In the present study, matrix-associated laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) was evaluated as an alternative method for capsular serotyping of H...
March 10, 2018: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://www.readbyqxmd.com/read/29534135/incidence-of-peri-implant-diseases-on-implants-with-and-without-laser-microgrooved-collar-a-5-year-retrospective-study-carried-out-in-private-practice-patients
#18
Renzo Guarnieri, Maurizio Grande, Francesco Zuffetti, Tiziano Testori
PURPOSE: To retrospectively evaluate the incidence of peri-implant mucositis and peri-implantitis around dental implants with the same body design and surface but different collar surface (laser-microgrooved vs not laser-microgrooved) after 5 years of loading in private practice patients. MATERIALS AND METHODS: The study was carried out on patients at a private dental clinic enrolled in a periodontal maintenance program, who received at least one implant with a laser-microgrooved collar surface and one implant without a laser-microgrooved collar surface...
March 2018: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/29532632/differential-antioxidant-enzyme-activity-in-rapid-response-glyphosate-resistant-ambrosia-trifida
#19
Nick T Harre, Haozhen Nie, Yiwei Jiang, Bryan G Young
BACKGROUND: The giant ragweed (Ambrosia trifida L.) rapid response (RR) biotype exhibits a sacrificial form of glyphosate resistance whereby an oxidative burst in mature leaves results in foliage loss, while juvenile leaves remain uninjured. This work investigates the safening capacity of antioxidant enzymes in RR juvenile leaves following glyphosate treatment and examines cross tolerance to paraquat. RESULTS: Basal antioxidant enzyme activities were similar between glyphosate-susceptible (GS) and RR biotypes...
March 12, 2018: Pest Management Science
https://www.readbyqxmd.com/read/29531066/cross-resistance-to-dicamba-2-4-d-and-fluroxypyr-in-kochia-scoparia-is-endowed-by-a-mutation-in-an-aux-iaa-gene
#20
Sherry LeClere, Chenxi Wu, Philip Westra, R Douglas Sammons
The understanding and mitigation of the appearance of herbicide-resistant weeds have come to the forefront of study in the past decade, as the number of weed species that are resistant to one or more herbicide modes of action is on the increase. Historically, weed resistance to auxin herbicides has been rare, but examples, such as Kochia scoparia L. Schrad (kochia), have appeared, posing a challenge to conventional agricultural practices. Reports of dicamba-resistant kochia populations began in the early 1990s in areas where auxin herbicides were heavily utilized for weed control in corn and wheat cropping systems, and some biotypes are resistant to other auxin herbicides as well...
March 12, 2018: Proceedings of the National Academy of Sciences of the United States of America
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