keyword
MENU ▼
Read by QxMD icon Read
search

diabetic foot infection AND/OR diabetic foot ulcer

keyword
https://www.readbyqxmd.com/read/29316701/the-effect-of-cryopreserved-human-placental-tissues-on-biofilm-formation-of-wound-associated-pathogens
#1
Yong Mao, Anya Singh-Varma, Tyler Hoffman, Sandeep Dhall, Alla Danilkovitch, Joachim Kohn
Biofilm, a community of bacteria, is tolerant to antimicrobial agents and ubiquitous in chronic wounds. In a chronic DFU (Diabetic Foot Ulcers) clinical trial, the use of a human cryopreserved viable amniotic membrane (CVAM) resulted in a high rate of wound closure and reduction of wound-related infections. Our previous study demonstrated that CVAM possesses intrinsic antimicrobial activity against a spectrum of wound-associated bacteria under planktonic culture conditions. In this study, we evaluated the effect of CVAM and cryopreserved viable umbilical tissue (CVUT) on biofilm formation of S...
January 8, 2018: Journal of Functional Biomaterials
https://www.readbyqxmd.com/read/29304937/an-economic-evaluation-of-the-impact-cost-and-medicare-policy-implications-of-chronic-nonhealing-wounds
#2
Samuel R Nussbaum, Marissa J Carter, Caroline E Fife, Joan DaVanzo, Randall Haught, Marcia Nusgart, Donna Cartwright
OBJECTIVE: The aim of this study was to determine the cost of chronic wound care for Medicare beneficiaries in aggregate, by wound type and by setting. METHODS: This retrospective analysis of the Medicare 5% Limited Data Set for calendar year 2014 included beneficiaries who experienced episodes of care for one or more of the following: arterial ulcers, chronic ulcers, diabetic foot ulcers, diabetic infections, pressure ulcers, skin disorders, skin infections, surgical wounds, surgical infections, traumatic wounds, venous ulcers, or venous infections...
January 2018: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/29275068/sucrose-octasulfate-dressing-versus-control-dressing-in-patients-with-neuroischaemic-diabetic-foot-ulcers-explorer-an-international-multicentre-double-blind-randomised-controlled-trial
#3
Michael Edmonds, José Luis Lázaro-Martínez, Jesus Manuel Alfayate-García, Jacques Martini, Jean-Michel Petit, Gerry Rayman, Ralf Lobmann, Luigi Uccioli, Anne Sauvadet, Serge Bohbot, Jean-Charles Kerihuel, Alberto Piaggesi
BACKGROUND: Diabetic foot ulcers are serious and challenging wounds associated with high risk of infection and lower-limb amputation. Ulcers are deemed neuroischaemic if peripheral neuropathy and peripheral artery disease are both present. No satisfactory treatment for neuroischaemic ulcers currently exists, and no evidence supports one particular dressing. We aimed to assess the effect of a sucrose octasulfate dressing versus a control dressing on wound closure in patients with neuroischaemic diabetic foot ulcers...
December 20, 2017: Lancet Diabetes & Endocrinology
https://www.readbyqxmd.com/read/29248237/the-society-for-vascular-surgery-wound-ischemia-and-foot-infection-wifi-classification-system-correlates-with-cost-of-care-for-diabetic-foot-ulcers-treated-in-a-multidisciplinary-setting
#4
Caitlin W Hicks, Joseph K Canner, Hikmet Karagozlu, Nestoras Mathioudakis, Ronald L Sherman, James H Black, Christopher J Abularrage
OBJECTIVE: We have previously demonstrated that the Society for Vascular Surgery Wound, Ischemia, and foot Infection (WIfI) classification correlates with wound healing time in patients with diabetic foot ulcers (DFUs) treated in a multidisciplinary setting. Our aim was to assess whether the charges and costs associated with DFU care increase with higher WIfI stages. METHODS: All patients presenting to our multidisciplinary diabetic limb preservation service from June 2012 to June 2016 were enrolled in a prospective database...
December 13, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/29204271/genome-sequencing-and-analysis-of-the-first-spontaneous-nanosilver-resistant-bacterium-proteus-mirabilis-strain-scdr1
#5
Amr T M Saeb, Khalid A Al-Rubeaan, Mohamed Abouelhoda, Manojkumar Selvaraju, Hamsa T Tayeb
Background: P. mirabilis is a common uropathogenic bacterium that can cause major complications in patients with long-standing indwelling catheters or patients with urinary tract anomalies. In addition, P. mirabilis is a common cause of chronic osteomyelitis in Diabetic foot ulcer (DFU) patients. We isolated P. mirabilis SCDR1 from a Diabetic ulcer patient. We examined P. mirabilis SCDR1 levels of resistance against Nanosilver colloids, the commercial Nanosilver and silver containing bandages and commonly used antibiotics...
2017: Antimicrobial Resistance and Infection Control
https://www.readbyqxmd.com/read/29151322/intralesional-epidermal-growth-factor-therapy-fordiabetic-foot-ulcers-an-evaluation-of-15-cases
#6
Meltem Işıkgöz Taşbakan, Ilgın Yıldırım Şimşir, Sinan Mermer, Serhat Uysal, Murat Öztürk, Şevki Çetinkalp
Background/aim: Intralesional recombinant epidermal growth factor (EGF) is a new treatment approach for diabetic foot ulcer, approved in 2006. EGF therapy is given as an adjunct to the standard treatment regimen of antibiotics, surgery, and hyperbaric oxygen. EGF accelerates the healing of diabetic foot ulcers and reduces healing time. This single-center study was conducted to evaluate the outcomes of intralesional EGF therapy in patients with diabetic foot ulcers.Materials and methods: We present the data of the follow-up patients treated in our clinics...
November 13, 2017: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/29148070/growth-factors-for-diabetic-foot-ulcers-mixed-treatment-comparison-analysis-of-randomized-clinical-trials
#7
Kannan Sridharan, Gowri Sivaramakrishnan
AIMS: Topical growth factors accelerate wound healing in patients with diabetic foot ulcers (DFU). Due to the absence of head to head comparisons, we carried out Bayesian network meta-analysis to compare the efficacy and safety of growth factors. METHODS: Using an appropriate search strategy, randomized controlled trials on topical growth factors compared with standard of care in patients with DFU, were included. Proportion of patients with complete healing was the primary outcome...
November 17, 2017: British Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/29131751/a-diabetic-foot-ulcer-treated-with-hydrogel-and-hyperbaric-oxygen-therapy-a-case-study
#8
P Aguiar, C Amaral, A Rodrigues, A H de Souza
This study reports on the case of an elderly patient, with diabetes, and a bullous wound on the left big toe that led to an amputation of the first and second left toes. The amputation was because of deep injury as it was not able to heal with a conventional treatment. After completing the normal treatment and the removal of a bacterial infection in the lesion, the patient underwent a treatment that was based on a hydrogel gel (0.9% saline solution) and hyperbaric oxygen therapy (HBOT). After 60 sessions of the therapy, almost complete closure of the wound was observed...
November 2, 2017: Journal of Wound Care
https://www.readbyqxmd.com/read/29131746/topical-oxygen-therapy-promotes-the-healing-of-chronic-diabetic-foot-ulcers-a-pilot-study
#9
P D Hayes, N Alzuhir, G Curran, I M Loftus
OBJECTIVE: Interventions that can heal or reduce diabetic foot ulcer (DFU) size may reduce the incidence of infection and amputation, and reduce associated social and economic costs. Many chronic wounds exhibit a degree of hypoxia and this leads to a reduction in healing processes including cell division and differentiation, angiogenesis, infection prevention, and collagen production. The aim of this pilot study was to assess the effects of a device supplying continuous oxygen ambulatory therapy on healing in chronic DFUs...
November 2, 2017: Journal of Wound Care
https://www.readbyqxmd.com/read/29110516/minimally-invasive-distal-metatarsal-diaphyseal-osteotomy-dmdo-for-chronic-plantar-diabetic-foot-ulcers
#10
Carlo Biz, Stefano Gastaldo, Miki Dalmau-Pastor, Marco Corradin, Andrea Volpin, Pietro Ruggieri
BACKGROUND: The aims of this prospective study were first to evaluate the safety and effectiveness of minimally invasive distal metatarsal diaphyseal osteotomies (DMDOs) for treating a consecutive series of diabetic patients with chronic plantar diabetic foot ulcers (CPDFUs) and second to assess their clinical-functional and radiographic outcomes. METHODS: A consecutive series of patients affected by diabetes mellitus with CPDFUs, not responsive to previous nonoperative management, underwent DMDO...
November 1, 2017: Foot & Ankle International
https://www.readbyqxmd.com/read/29091034/updating-the-diabetic-foot-treatment-algorithm-recommendations-on-treatment-using-advanced-medicine-and-therapies
#11
Peter Blume, Stephanie Wu
OBJECTIVE: Since the last diabetic foot ulcer (DFU) treatment algorithm was published in 2002, new options for diagnostic testing and treatments have been developed. This study seeks to update the DFU treatment algorithm to include new options available in diagnostic testing and treatment. MATERIALS AND METHODS: A computerized literature search of peer-reviewed articles published between January 2003 and January 2016 was conducted using MEDLINE (PubMed), EMBASE, and the Cochrane Library...
October 20, 2017: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/29083500/prognosis-of-the-infected-diabetic-foot-ulcer-a-12-month-prospective-observational-study
#12
Mwidimi Ndosi, Alexandra Wright-Hughes, Sarah Brown, Michael Backhouse, Benjamin A Lipsky, Moninder Bhogal, Catherine Reynolds, Peter Vowden, Edward Jude, Jane Nixon, E Andrea Nelson
AIMS: To determine clinical outcomes and explore prognostic factors related to ulcer healing in people with a clinically infected diabetic foot ulcer. METHODS: This multicentre, prospective, observational study reviewed participants' data at 12 months after culture of a diabetic foot ulcer requiring antibiotic therapy. From participants' notes, we obtained information on the incidence of wound healing, ulcer recurrence, lower extremity amputation, lower extremity revascularization and death...
October 30, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/29058098/osteomyelitis-of-the-lower-extremity-pathophysiology-imaging-and-classification-with-an-emphasis-on-diabetic-foot-infection
#13
Jacob C Mandell, Bharti Khurana, Jeremy T Smith, Gregory J Czuczman, Varand Ghazikhanian, Stacy E Smith
Osteomyelitis is inflammation of the bone caused by an infectious organism, and is a difficult clinical problem. The pathophysiology, imaging, and classification of osteomyelitis are challenging, varying with the age of the patient (child versus adult), the chronicity of the infection (acute versus chronic), and the route of spread (hematogenous versus contiguous focus), as well as the immune and vascular status of the patient and affected region. The two most common classification schemes are those of Lew and Waldvogel, and Cierny and Mader...
October 20, 2017: Emergency Radiology
https://www.readbyqxmd.com/read/29057728/-a-multidisciplinary-approach-in-diabetic-foot-disease-is-mandatory
#14
J G van Baal, W B Aan de Stegge, N C Schaper
The history of two patients (66- and 53-year-old males) with diabetes and peripheral neuropathy illustrates the variety of clinical presentations and pitfalls in treatment of diabetic foot ulcers. Peripheral arterial disease and mechanical stress as a consequence of peripheral neuropathy are important risk factors for developing an ulcer and eventually loss of a limb. Revascularisation of the limb should be considered in the presence of critical limb ischaemia or in the presence of mild to severe ischaemia in combination with a deep infection...
2017: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/29046049/treatment-of-diabetic-foot-ulcers-with-therapeutic-magnetic-resonance-tmr%C3%A2-improves-the-quality-of-granulation-tissue
#15
Letizia Ferroni, Chiara Gardin, Andrea De Pieri, Maria Sambataro, Elena Seganfreddo, Chiara Goretti, Elisabetta Iacopi, Barbara Zavan, Alberto Piaggesi
Diabetic foot ulcers (DFUs) often result in severely adverse outcomes, such as serious infections, hospitalization, and lower extremity amputations. In last few years, to improve the outcome of DFUs, clinicians and researchers put their attention on the application of low intensity pulsating electro-magnetic fields through Therapeutic Magnetic Resonance (TMR®). In our study, patients with DFUs have been divided into two groups: The Sham Group treated with non-functioning TMR® device, and the Active Group treated with a functioning device...
August 7, 2017: European Journal of Histochemistry: EJH
https://www.readbyqxmd.com/read/29042175/calcitriol-promotes-proangiogenic-molecules-in-keratinocytes-in-a-diabetic-foot-ulcer-model
#16
Valentin Trujillo, Paulina Marín-Luevano, Irma González-Curiel, Adrián Rodríguez-Carlos, Maira Ramírez-Reyes, Esther Layseca-Espinosa, José A Enciso-Moreno, Lorenza Díaz, Bruno Rivas-Santiago
Foot ulceration is one of the most common and complex sequelae of diabetes mellitus, generally posing a therapeutic challenge due to poor healing responses and high rates of complications, including peripheral vascular disease, ischemia and infections. Calcitriol, the most active vitamin D metabolite, induces antimicrobial peptides production in keratinocytes from diabetic foot ulcers (DFU); however, little is known about its effects on angiogenic factors in this pathology. Herein we aimed at studying whether calcitriol induces angiogenic molecules in keratinocytes under normoxic and hypoxic conditions, and if these molecules are able to improve cell migration in vitro...
November 2017: Journal of Steroid Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/29017807/unplanned-30-day-readmission-in-patients-with-diabetic-foot-wounds-treated-in-a-multidisciplinary-setting
#17
Courtenay M Holscher, Caitlin W Hicks, Joseph K Canner, Ronald L Sherman, Mahmoud B Malas, James H Black, Nestoras Mathioudakis, Christopher J Abularrage
OBJECTIVE: Readmission rates are known to be high for vascular surgery patients in general, but there are limited data describing the risk of surgical and nonsurgical readmission among patients with diabetic foot ulcers (DFUs). Our aim was to identify factors associated with unplanned readmission in DFU patients treated in a multidisciplinary setting. METHODS: We studied a single-center cohort of patients enrolled in a multidisciplinary diabetic foot service (July 2012-June 2017)...
October 7, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/29017535/the-leucopatch%C3%A2-system-in-the-management-of-hard-to-heal-diabetic-foot-ulcers-study-protocol-for-a-randomised-controlled-trial
#18
Frances Game, William Jeffcoate, Lise Tarnow, Florence Day, Deborah Fitzsimmons, Judith Jacobsen
BACKGROUND: Diabetic foot ulcers are a common and severe complication of diabetes mellitus. Standard treatment includes debridement, offloading, management of infection and revascularisation where appropriate, although healing times may be long. The LeucoPatch® device is used to generate an autologous platelet-rich fibrin and leucocyte wound dressing produced from the patient's own venous blood by centrifugation, but without the addition of any reagents. The final product comprises a thin, circular patch composed predominantly of fibrin together with living platelets and leucocytes...
October 10, 2017: Trials
https://www.readbyqxmd.com/read/28951333/complications-during-the-treatment-of-diabetic-foot-osteomyelitis
#19
Suzanne A V van Asten, Moez Mithani, Edgar J G Peters, Javier La Fontaine, Paul J Kim, Lawrence A Lavery
AIM: To identify complications of medical treatment in patients with diabetic foot osteomyelitis (DFO). METHODS: We reviewed 143 records of consecutive patients admitted with DFO, confirmed by bone histopathology or culture. Complications monitored included acute kidney injuries (AKI), development of methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus (VRE), gastrointestinal complications, and venous catheter related complications during a 12months follow-up period...
June 13, 2017: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/28949996/the-impact-of-team-based-interprofessional-comprehensive-assessments-on-the-diagnosis-and-management-of-diabetic-foot-ulcers-a-retrospective-cohort-study
#20
Ranjani Somayaji, James A Elliott, Reneeka Persaud, Morgan Lim, Laurie Goodman, R Gary Sibbald
BACKGROUND: Diabetic foot ulcers (DFU) are increasingly prevalent, and associated with significant morbidity, mortality, and cost. An interprofessional approach to DFU management is critical given the etiological complexity involved. This study aimed to assess the impact of an interprofessional team approach on DFU diagnosis and management for a cohort of patients receiving treatment in an Ontario Canada home care setting. METHODS: A retrospective cohort study of patients attending a large regional Community Care Access Centre (CCAC) between February 11, 2013-September 30, 2014 was conducted...
2017: PloS One
keyword
keyword
83988
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"