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https://www.readbyqxmd.com/read/29277139/perception-and-practices-of-nomadic-women-in-a-rural-community-in-southwestern-nigeria-to-their-children-s-oral-health
#1
Olubunmi Olusola Bankole, Folake Barakat Lawal, Abimbola Balogun
Introduction Nomads move from one settlement to another, thus it has been difficult to have adequate documentation about their oral health and that of their children. Aim To investigate the perception and practices of nomadic Fulani women toward their children's oral health. Methodology A cross-sectional study was conducted among 197 Fulani women using a structured interviewer administered questionnaire. Results Perceived causes of tooth decay included tooth germs/worms (23.9%) and sugar (5.1%), and 32.0%, 15...
January 1, 2017: International Quarterly of Community Health Education
https://www.readbyqxmd.com/read/29275570/-three-dimensional-printed-miniplate-used-for-maxillary-protraction
#2
S R Liang, F Wang, D Q Zhou, S Chang, Y X Bai
The miniplate was designed and three-dimensional (3D) printed according to the positions of roots and tooth germs and then it was used as skeletal anchorage to protract the maxilla. The maxilla moved forward obviously after treatment. Custom designed and 3D printed miniplate could be used for maxillary protraction.
December 9, 2017: Zhonghua Kou Qiang Yi Xue za Zhi, Zhonghua Kouqiang Yixue Zazhi, Chinese Journal of Stomatology
https://www.readbyqxmd.com/read/29249735/longitudinal-observation-of-maxillary-sinus-bony-bridges-and-septa-in-childhood
#3
Munetaka Naitoh, Hirofumi Watanabe, Kazuhito Yoshida, Hisashi Hayashi, Kenichi Gotoh, Eiichiro Ariji
The rate of septum presence in the maxillary sinus has been reported to be over 30%. It was considered that a bony bridge might change to a maxillary sinus septum with growth in a previous study using dry child skulls. In the present investigation, maxillary sinus bony bridges and septa were longitudinally observed using computed tomography (CT). Multislice CT was performed in three patients. A bony bridge was defined as a bony structure between the maxillary sinus wall and dental germ. Also, a septum was defined as a pointed bony structure in the inferior wall of the maxillary sinus...
2017: Okajimas Folia Anatomica Japonica
https://www.readbyqxmd.com/read/29229314/an-atypical-odontogenic-myxoma
#4
L Benjelloun, N Cherradi, A Kessab, S Dghoughi
INTRODUCTION: Odontogenic myxoma is an uncommon tumor of the jaws, benign but locally invasive. It arises from the mesenchymal portion of the tooth germ. It has a variable non-specific clinical and radiological appearance, and may be confused with other lesions of the jaws. CASE REPORT: A patient aged 50 presented for a periodontal treatment. After routine retroalveolar x-rays, we noted a small limited radiolucency between the left mandibular canine and the left mandibular first premolar...
December 8, 2017: Journal of Stomatology, Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29223396/accelerated-dentinogenesis-by-inhibiting-the-mitochondrial-fission-factor-dynamin-related-protein-1
#5
Yumiko Matsuishi, Hiroki Kato, Keiji Masuda, Haruyoshi Yamaza, Yuta Hirofuji, Hiroshi Sato, Hiroko Wada, Tamotsu Kiyoshima, Kazuaki Nonaka
Undifferentiated odontogenic epithelium and dental papilla cells differentiate into ameloblasts and odontoblasts, respectively, both of which are essential for tooth development. These differentiation processes involve dramatic functional and morphological changes of the cells. For these changes to occur, activation of mitochondrial functions, including ATP production, is extremely important. In addition, these changes are closely related to mitochondrial fission and fusion, known as mitochondrial dynamics...
December 6, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/29155305/hey1-and-hey2-are-differently-expressed-during-mouse-tooth-development
#6
Kotono Kibe, Mitsushiro Nakatomi, Shinji Kataoka, Takashi Toyono, Yuji Seta
The Hey family (also known as Chf, Herp, Hesr, and Hrt) is a set of Hairy/Enhancer of Split-related basic helix-loop-helix type transcription factors. Hey1, Hey2, and HeyL have been identified in mammals. Although Hey proteins are known to regulate cardiovascular development, muscle homeostasis, osteogenesis, neurogenesis, and oncogenesis, their roles in tooth development have been largely obscure. Therefore, this study aimed to clarify detailed spatiotemporal expression patterns of Hey1 and Hey2 in developing molars and incisors of mice by section in situ hybridization...
November 16, 2017: Gene Expression Patterns: GEP
https://www.readbyqxmd.com/read/29148101/homeobox-protein-msx-1-inhibits-expression-of-bone-morphogenetic-protein-2-bone-morphogenetic-protein-4-and-lymphoid-enhancer-binding-factor-1-via-wnt-%C3%AE-catenin-signaling-to-prevent-differentiation-of-dental-mesenchymal-cells-during-the-late-bell-stage
#7
Xiao-Yu Feng, Xiao-Shan Wu, Jin-Song Wang, Chun-Mei Zhang, Song-Lin Wang
Homeobox protein MSX-1 (hereafter referred to as MSX-1) is essential for early tooth-germ development. Tooth-germ development is arrested at bud stage in Msx1 knockout mice, which prompted us to study the functions of MSX-1 beyond this stage. Here, we investigated the roles of MSX-1 during late bell stage. Mesenchymal cells of the mandibular first molar were isolated from mice at embryonic day (E)17.5 and cultured in vitro. We determined the expression levels of β-catenin, bone morphogenetic protein 2 (Bmp2), Bmp4, and lymphoid enhancer-binding factor 1 (Lef1) after knockdown or overexpression of Msx1...
November 17, 2017: European Journal of Oral Sciences
https://www.readbyqxmd.com/read/29129749/quantitative-proteomic-analysis-of-deciduous-molars-during-cap-to-bell-transition-in-miniature-pig
#8
Yang Li, Yiyi Gong, Xiaoshan Wu, Fu Wang, Yilin Xie, Zhao Zhu, Yingying Su, Jinsong Wang, Chunmei Zhang, Junqi He, Haiteng Deng, Songlin Wang
Taking advantage of genetic manipulation tools and accessibility, almost all molecular knowledge on vertebrate tooth development was obtained from rodent models that only have one dentition in their entire lives. Whether the tooth development in other vertebrates such as swine or human follows the same rules remains elusive. Rodent dentitions differ considerably from human dentitions, therefore limiting the application of knowledge from rodent tooth to human tooth. Signal-mediated communication between cells and complex gene and protein regulatory networks are key components of tooth development...
November 10, 2017: Journal of Proteomics
https://www.readbyqxmd.com/read/29090496/primordial-odontogenic-tumor-a-case-report-with-histopathological-analyses
#9
Toshinari Mikami, Yu Ohashi, Ronell Bologna-Molina, Adalberto Mosqueda-Taylor, Naoki Fujiwara, Naoko Tsunoda, Hiroyuki Yamada, Yasunori Takeda
Primordial odontogenic tumor (POT) is a benign mixed epithelial and mesenchymal odontogenic tumor included into the current World Health Organization (WHO) classification of Head and Neck tumours in 2017. As far as the authors have confirmed, only eight cases of this tumor have been reported so far. This paper reports a case of POT that occurred in the right mandible of a 5-year-old patient. Panoramic radiograph showed a well-defined homogeneous radiolucency displacing the unerupted second deciduous molar to the deep part of the mandible...
November 1, 2017: Pathology International
https://www.readbyqxmd.com/read/29090126/multidisciplinary-management-of-a-fused-maxillary-central-incisor-moved-through-the-midpalatal-suture-a-case-report
#10
Hakan Bulut, Aylin Pasaoglu
Fusion of teeth is a developmental anomaly. It occurs at the stage of tooth formation, which determines the shape and size of the tooth crown, when one or more teeth fuse at the dentin level during the morphodifferentiation of the dental germs. Such teeth show macrodontia and may cause crowding, as well as esthetic and endodontic problems. In this article, we report a rare case of a maxillary central incisor fused to a supernumerary tooth showing labial and palatal talon cusps, which was orthodontically moved across the midpalatal suture...
November 2017: Korean Journal of Orthodontics
https://www.readbyqxmd.com/read/29072251/conservative-surgical-treatment-of-the-jaw-cysts-in-children-case-study-of-five-patients
#11
G Gurler, S Yilmaz, C Delilbasi, E Dilaver, E Yuzbasioglu, A Patir-Munevveroglu
AIMS: Conservative treatment of jaw cysts establishes low surgical complication risk and protects vital anatomical structures such as inferior alveolar nerve, maxillary sinus and permanent tooth germs. Marsupialization and decompression have been widely used in children. The aim of this study was to evaluate the results of the conservative treatment of jaw cysts in five children. MATERIALS AND METHODS: This article presents case series of marsupialization in jaw cysts associated with impacted teeth in five children...
September 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/29034895/generation-of-induced-pluripotent-stem-cell-ipsc-line-from-charcot-marie-tooth-disease-patient-with-mpz-mutation-cmt1b
#12
Daryeon Son, Phil Jun Kang, Wonjin Yun, Seungkwon You
Charcot-Marie-Tooth disease (CMT1B) is an inherited neurological disorder caused by mutation of the myelin protein zero (MPZ) gene. We generated an induced pluripotent stem cell (iPSC) line from an 81-year-old patient with CMT1B by electroporating of lymphoblastoid cell lines with episomal plasmids encoding OCT4, SOX2, KLF4, L-MYC, LIN28, and p53-targeting shRNA. The established iPSCs expressed various pluripotency markers, demonstrated the potential to differentiate into cells of the three germ layers in vitro, had a normal karyotype and retained the MPZ mutation...
October 2017: Stem Cell Research
https://www.readbyqxmd.com/read/28955954/lgr4-is-required-for-sequential-molar-development
#13
Yukiko Yamakami, Koki Kohashi, Kazunori Oyama, Yasuaki Mohri, Shizu Hidema, Katsuhiko Nishimori
Tooth development requires proliferation, differentiation, and specific migration of dental epithelial cells, through well-organized signaling interactions with mesenchymal cells. Recently, it has been reported that leucine-rich repeat-containing G protein coupled receptor 4 (LGR4), the receptor of R-spondins, is expressed in many epithelial cells in various organs and tissues and is essential for organ development and stem cell maintenance. Here, we report that LGR4 contributes to the sequential development of molars in mice...
December 2016: Biochemistry and Biophysics Reports
https://www.readbyqxmd.com/read/28942297/ameloblastoma-of-the-jaw-in-three-species-of-rodent-a-domestic-brown-rat-rattus-norvegicus-syrian-hamster-mesocricetus-auratus-and-amargosa-vole-microtus-californicus-scirpensis
#14
B Murphy, A Michel, E B LaDouceur, C Bell, M Lin, D M Imai
Ameloblastoma is a locally aggressive tumour derived from the odontogenic epithelium of the developing tooth germ. This uncommon odontogenic tumour is generally considered benign, but rarely, both distant metastasis and cytological atypia occur and this malignant version is referred to as malignant ameloblastic carcinoma. Here we document a spontaneous malignant ameloblastic carcinoma in a rat (Rattus norvegicus) with metastasis to the submandibular lymph node. We also describe ameloblastomas in two other muroid rodents, an Amaragosa vole (Microtus californicus scirpensis) and a Syrian hamster (Mesocricetus auratus)...
August 2017: Journal of Comparative Pathology
https://www.readbyqxmd.com/read/28933666/regulation-of-proliferation-in-developing-human-tooth-germs-by-msx-homeodomain-proteins-and-cyclin-dependent-kinase-inhibitor-p19ink4d
#15
Darko Kero, Katarina Vukojevic, Petra Stazic, Danijela Sundov, Snjezana Mardesic Brakus, Mirna Saraga-Babic
Before the secretion of hard dental tissues, tooth germs undergo several distinctive stages of development (dental lamina, bud, cap and bell). Every stage is characterized by specific proliferation patterns, which is regulated by various morphogens, growth factors and homeodomain proteins. The role of MSX homeodomain proteins in odontogenesis is rather complex. Expression domains of genes encoding for murine Msx1/2 during development are observed in tissues containing highly proliferative progenitor cells. Arrest of tooth development in Msx knockout mice can be attributed to impaired proliferation of progenitor cells...
October 2, 2017: Organogenesis
https://www.readbyqxmd.com/read/28928009/oropharyngeal-epignathus-with-partial-facial-duplication-report-of-a-rare-case
#16
M Herath, B S M S Siriwardena, R D Jayasinghe, D K Dias
Foetal oral teratoma or epignathus is a rare benign condition that originates in the oropharyngeal region. The term 'teratoma' refers to a mass composed of poorly organized tissues derived from each of the three germ layers. Epignathus may occur when one twin ceases development during gestation and becomes vestigial to the fully formed dominant twin. The reported incidence of epignathus is approximately 1:35,000 to 1:200,000 live births. A unique case of partial facial duplication with gross histological and radiological evidence of partial duplication of the facial elements and organs is presented herein...
September 16, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28914240/comparison-of-candida-species-isolated-from-children-with-and-without-early-childhood-caries-a-descriptive-cross-sectional-study
#17
M S Beena, Faizal C Peedikayil, M B GufranAfmed, T P Chandru, K Soni, N Dhanesh
BACKGROUND: Early childhood caries (ECC) is characterized by the presence of one or more decayed, missing (due to caries), or filled teeth surfaces in any primary tooth, in a child below 6 years of age. Although ECC is primarily associated with high levels of maternal Streptococcus mutans, there has been an increased interest in finding the relationship between oral fungal flora and dental caries. OBJECTIVE: The aim of the study is to identify and characterize the Candida species and to compare the candidal isolates in children with ECC and without ECC...
October 2017: Journal of the Indian Society of Pedodontics and Preventive Dentistry
https://www.readbyqxmd.com/read/28892649/expression-of-phosphate-transporters-during-dental-mineralization
#18
L Merametdjian, S Beck-Cormier, N Bon, G Couasnay, S Sourice, J Guicheux, C Gaucher, L Beck
The importance of phosphate (Pi) as an essential component of hydroxyapatite crystals suggests a key role for membrane proteins controlling Pi uptake during mineralization in the tooth. To clarify the involvement of the currently known Pi transporters (Slc17a1, Slc34a1, Slc34a2, Slc34a3, Slc20a1, Slc20a2, and Xpr1) during tooth development and mineralization, we determined their spatiotemporal expression in murine tooth germs from embryonic day 14.5 to postnatal day 15 and in human dental samples from Nolla stages 6 to 9...
September 1, 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/28880717/bivalent-histone-codes-on-wnt5a-during-odontogenic-differentiation
#19
Y Zhou, L Zheng, F Li, M Wan, Y Fan, X Zhou, W Du, C Pi, D Cui, B Zhang, J Sun, X Zhou
Lineage-committed differentiation is an essential biological program during odontogenesis, which is tightly regulated by lineage-specific genes. Some of these genes are modified by colocalization of H3K4me3 and H3K27me3 marks at promoter regions in progenitors. These modifications, named "bivalent domains," maintain genes in a poised state and then resolve for later activation or repression during differentiation. Wnt5a has been reported to promote odontogenic differentiation in dental mesenchyme. However, relatively little is known about the epigenetic modulations on Wnt5a activation during tooth development...
January 2018: Journal of Dental Research
https://www.readbyqxmd.com/read/28832934/relative-tooth-size-at-birth-in-primates-life-history-correlates
#20
Timothy D Smith, Magdalena N Muchlinski, Wade R Bucher, Christopher J Vinyard, Christopher J Bonar, Sian Evans, Lawrence E Williams, Valerie B DeLeon
OBJECTIVES: Dental eruption schedules have been closely linked to life history variables. Here we examine a sample of 50 perinatal primates (28 species) to determine whether life history traits correlate with relative tooth size at birth. MATERIALS AND METHODS: Newborn primates were studied using serial histological sectioning. Volumes of deciduous premolars (dp(2) -dp(4) ), replacement teeth (if any), and permanent molars (M(1-2/3) ) of the upper jaw were measured and residuals from cranial length were calculated with least squares regressions to obtain relative dental volumes (RDVs)...
November 2017: American Journal of Physical Anthropology
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