Valentina Gnoni, Michel Mesquita, David O'Regan, Alessio Delogu, Ivan Chakalov, Andrea Antal, Allan H Young, Romola S Bucks, Melinda L Jackson, Ivana Rosenzweig
INTRODUCTION: Obstructive sleep apnoea (OSA) is a multisystem, debilitating, chronic disorder of breathing during sleep, resulting in a relatively consistent pattern of cognitive deficits. More recently, it has been argued that those cognitive deficits, especially in middle-aged patients, may be driven by cardiovascular and metabolic comorbidities, rather than by distinct OSA-processes, such as are for example ensuing nocturnal intermittent hypoxaemia, oxidative stress, neuroinflammation, and sleep fragmentation...
April 6, 2023: Front Sleep