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https://www.readbyqxmd.com/read/29471459/descriptive-texture-analyses-of-broiler-breast-fillets-with-the-wooden-breast-condition-stored-at-4%C3%A2-c-and-20%C3%A2-c
#1
G Sanchez Brambila, B C Bowker, D Chatterjee, H Zhuang
The objective of this study was to evaluate the effects of the wooden breast (WB) condition on the texture of cooked broiler breast fillets (Pectoralis major) after fresh and frozen storage. Texture characteristics of normal (NORM) and severe WB fillets were studied by both sensory descriptive analyses and Warner-Bratzler shear force. Broiler breast fillets were collected over 3 separate trial days from a commercial deboning line at 3 h postmortem, classified according to the wooden breast condition, and then stored at either 4°C or -20°C prior to cooking and texture evaluation...
February 16, 2018: Poultry Science
https://www.readbyqxmd.com/read/29470820/the-impact-of-intraoperative-re-resection-of-a-positive-bile-duct-margin-on-clinical-outcomes-for-hilar-cholangiocarcinoma
#2
Xu-Feng Zhang, Malcolm H Squires, Fabio Bagante, Cecilia G Ethun, Ahmed Salem, Sharon M Weber, Thuy Tran, George Poultsides, Andre Y Son, Ioannis Hatzaras, Linda Jin, Ryan C Fields, Matthew Weiss, Charles Scoggins, Robert C G Martin, Chelsea A Isom, Kamron Idrees, Harveshp D Mogal, Perry Shen, Shishir K Maithel, Carl R Schmidt, Timothy M Pawlik
BACKGROUND: The impact of re-resection of a positive intraoperative bile duct margin on clinical outcomes for resectable hilar cholangiocarcinoma (HCCA) remains controversial. We sought to define the impact of re-resection of an initially positive frozen-section bile duct margin on outcomes of patients undergoing surgery for HCCA. METHODS: Patients who underwent curative-intent resection for HCCA between 2000 and 2014 were identified at 10 hepatobiliary centers...
February 22, 2018: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/29461902/excision-of-nodular-basal-cell-carcinoma-involving-the-lower-eyelid-tarsal-skin-using-a-grey-line-splitting-posterior-lamella-sparing-technique
#3
Vincent Qin, Dion Paridaens
PURPOSE: To describe a posterior lamella-sparing technique to resect nodular basal cell carcinoma involving the inferior part of the tarsal skin of the lower eyelid. SURGICAL TECHNIQUE: Excision of nodular basal cell carcinoma of the tarsal skin using a grey-line-splitting technique with preservation of the posterior lamella. Specimen was sent for frozen section control. Additional excision was performed in caseof irradicality. The defect was closed with a free skin graft from the ipsi- or contralateral upper eyelid...
February 20, 2018: Orbit
https://www.readbyqxmd.com/read/29461446/evaluating-the-utility-of-the-lateral-elbow-radiograph-in-central-articular-olecranon-reduction-an-anatomic-and-radiographic-study
#4
Jeremy Kubik, Prism Schneider, Richard Buckley, Robert Korley, Paul Duffy, Ryan Martin
OBJECTIVES: The surgical reduction of intra-articular olecranon fractures is judged primarily on the lateral elbow radiograph, as orthogonal imaging of the articular surface is not obtainable. We sought to determine surgeon accuracy in identifying intra-articular olecranon malreductions on the lateral elbow radiograph. METHODS: Six human fresh-frozen cadaveric elbow specimens were sagittally sectioned in 5-mm increments after olecranon dissection, preservation of soft tissue envelope, and rigid fixation of the elbow in an external fixator...
March 2018: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/29451373/regional-structural-and-functional-specialisations-in-the-urethra-of-the-female-rat-evidence-for-complex-physiological-control-systems
#5
Monica Eggermont, Stefan De Wachter, Jane Eastham, James Gillespie
The present study characterises the complex structural and functional elements of the female rat urethra that may be involved in controlling urethral closure and continence. Urethras were dissected from female Sprague-Dawley rats (n=12) euthanized by pentobarbital overdose. Tissues were fixed (4% paraformaldehyde), frozen and sectioned (8μm) for light microscopy and immunohistochemistry. Antibodies were used to detect immunoreactivity to calcitonin gene related peptide, nitric oxide synthase, vesicular acetylcholine transporter and tyrosine hydroxylase...
February 16, 2018: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
https://www.readbyqxmd.com/read/29445296/the-ultrasound-guided-retrolaminar-block-volume-dependent-injectate-distribution
#6
Marija Damjanovska, Tatjana Stopar Pintaric, Erika Cvetko, Kamen Vlassakov
Purpose: The ultrasound-guided retrolaminar block is one of the newer and simpler alternatives to the traditional, often technically challenging, paravertebral (PV) block. Its feasibility, safety, and efficacy have already been clinically demonstrated in patients with multiple rib fractures using higher volumes of local anesthetic, when compared with the traditional approach. The primary aim of this observational anatomical study was to assess the spread of local anesthetic from the retrolaminar injection point to the PV space and its volume dependence...
2018: Journal of Pain Research
https://www.readbyqxmd.com/read/29443775/primary-undifferentiated-pleomorphic-sarcoma-of-the-thyroid-a-case-report-and-review-of-the-literature
#7
REVIEW
Qiang Chen, Qing Huang, Jia-Xin Yan, Chao Li, Jin-Yi Lang
RATIONALE: Primary undifferentiated pleomorphic sarcoma is extremely rare in the thyroid, and can be easily misdiagnosed as anaplastic thyroid cancer. PATIENT CONCERNS: We present a case of a 71-year-old woman who presented with a rapidly growing painless mass in the neck. DIAGNOSES-INTERVENTIONS-OUTCOMES: Computed tomography showed a large hypointense mass with hyperdense areas involving whole of the right lobe of thyroid gland and fine-needle aspiration cytology found a few atypical cells...
February 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29439810/differential-expression-of-proteome-in-aqueous-humor-in-patients-with-and-without-glaucoma
#8
D Salamanca, J L Gómez-Chaparro, A Hidalgo, F Labella
OBJECTIVE: To determine quantitative and qualitative differences of aqueous humor proteome in patients with and without glaucoma. METHOD: Observational, descriptive and cross-sectional study of 12 patients (8 men; 4 women) with and without glaucoma. There are 3 groups of minority proteins with serum equimolar contribution of each of the patients. Specimens were obtained during cataract surgery from patients without glaucoma (performed with retrobulbar anaesthesia [cataract retrobulbar patient -CRP-;n=4] or topical [cataract topical patient -CTP-; n=4]), or from patients with glaucoma (performed with retrobulbar anaesthesia [glaucoma retrobulbar patient -GRP-; n=4])...
February 10, 2018: Archivos de la Sociedad Española de Oftalmología
https://www.readbyqxmd.com/read/29434872/regulator-of-g-protein-signaling-5-enhances-portal-vein-invasion-in-hepatocellular-carcinoma
#9
Yumi Umeno, Sachiko Ogasawara, Jun Akiba, Satoshi Hattori, Hironori Kusano, Osamu Nakashima, Hironori Koga, Takuji Torimura, Ryoji Yamakawa, Hirohisa Yano
Portal vein invasion (PVI) is a major prognostic factor in hepatocellular carcinoma (HCC). The aim of the present study was to identify molecules that regulate PVI. Sections of cancerous tissue, paired noncancerous tissue and the PVI area were collected from 3 frozen HCC sections, using laser microdissection. The present study focused on 3 upregulated molecules, integrin β3 (ITGB3), secreted phosphoprotein 1 (SPP1) and regulator of G-protein signaling 5 (RGS5), and 2 molecules that were downregulated in PVI tissue compared with cancer tissue, metallothionein 1G (MT1G) and metallothionein 1H (MT1H), as determined by cDNA microarray analysis...
February 2018: Oncology Letters
https://www.readbyqxmd.com/read/29433175/the-alar-ligaments-a-cadaveric-and-radiologic-comparison-study
#10
Juan P Sardi, Joe Iwanaga, Vlad Voin, Cameron Schmidt, Marios Loukas, Jens R Chapman, Rod J Oskouian, R Shane Tubbs
OBJECTIVE: A precise anatomical description of the alar ligaments is important to better understand their biomechanical and pathologic implications. Although there are several studies regarding their anatomy, the literature is inconsistent. To our knowledge, there are no reports that compare cadaveric morphologic findings with computed tomography (CT) images of the alar ligaments. METHODS: Eight sides from 4 fresh-frozen cadaveric specimens were used in this study...
February 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29430182/new-horizons-in-surgical-treatment-of-ground-glass-nodules-of-the-lung-experience-and-controversies
#11
REVIEW
Donglai Chen, Chenyang Dai, Xiermaimaiti Kadeer, Rui Mao, Yongbing Chen, Chang Chen
Ground-glass nodule (GGN) is defined as a nodular shadow with ground-glass opacity that is generally associated with the early-stage lung adenocarcinoma. Nowadays, GGNs of the lung are increasingly detected with thin-section computed tomography scan. GGNs are categorized as pure GGNs and mixed GGNs according to the images from a high-resolution computed tomography. Meanwhile, it is routine to divide GGNs into different categories according to the number, solitary, or multiple, the management of which there is very different...
2018: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/29427472/impact-of-serum-ca19-9-level-on-prognosis-and-prediction-of-lymph-node-metastasis-in-patients-with-intrahepatic-cholangiocarcinoma
#12
Toru Yamada, Yoshitsugu Nakanishi, Keisuke Okamura, Takahiro Tsuchikawa, Toru Nakamura, Takehiro Noji, Toshimichi Asano, Kimitaka Tanaka, Yo Kurashima, Yuma Ebihara, Soichi Murakami, Toshiaki Shichinohe, Tomoko Mitsuhashi, Satoshi Hirano
BACKGROUND AND AIM: Lymph node metastasis is an important prognostic factor for intrahepatic cholangiocarcinoma (ICC), but accurate preoperative diagnosis is difficult. The aim of this study was to measure the concentration of serum carbohydrate antigen 19-9 (s-CA19-9) as a preoperative predictor of lymph node metastasis. METHODS: In our department, curative-intent hepatectomy for ICC has been performed only once the absence of metastases in para-aortic lymph nodes (PALN) has been confirmed from intraoperative frozen-section pathological examinations...
February 10, 2018: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29426182/dissolved-organic-carbon-fractionation-accelerates-glacier-melting-a-case-study-in-the-northern-tibetan-plateau
#13
Zhaofu Hu, Shichang Kang, Fangping Yan, Yulan Zhang, Yang Li, Pengfei Chen, Xiang Qin, Kun Wang, Shaopeng Gao, Chaoliu Li
In glacierized regions, melting process has a significant effect on concentrations and light absorption characteristics of dissolved organic carbon (DOC), potentially resulting in variations of its radiative forcing, which is not yet relevant research at glacier region of the Tibetan Plateau (TP). In this study, DOC fractionation and its radiative forcing change during the melting process were investigated at Laohugou glacier No. 12 (LHG glacier) in western Qilian Mts., northern TP. DOC concentrations in fresh snow, snowpit and surface ice samples were 0...
February 1, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29424924/hur-ttp-and-mir-133b-expression-in-nsclc-and-their-association-with-prognosis
#14
L Qian, A-H Ji, W-J Zhang, N Zhao
OBJECTIVE: This study sought to explore HuR, Thrombotic Thrombocytopenic Purpura (TTP), and microRNA 133b (miR-133b) expression levels in non-small cell lung cancer (NSCLC) patients and assess the relationship of expression with disease prognosis. PATIENTS AND METHODS: One hundred and ten paraffin-embedded and 33 fresh flash-frozen NSCLC samples, together with matched tumor adjacent normal tissue controls, were collected from patients between January 2013 and July 2015 in Yidu Central Hospital of Weifang...
January 2018: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29417283/depleted-lamin-b1-a-possible-marker-of-the-involvement-of-senescence-in-endometriosis
#15
Helena Malvezzi, Bruno Gallani Viana, Cristine Dobo, Renee Zon Filippi, Sérgio Podgaec, Carla Azevedo Piccinato
PROPOSE: Endometriosis is a benign disease characterized by implantation and the growth of endometrial tissue outside the uterine cavity and it shares similarities with cancer. Lamin B1, p16 and p21 play a role on cell cycle regulation, development, cell repair and its activities are related to cancers. Considering the similarities between endometriosis and cancer, the aim of the present cross-sectional study is to detect p16, p21 and Lamin B1 in the ectopic endometrium of patients with endometriosis (n = 8) with eutopic (n = 8) and control endometrium (n = 8) and relate them to the maintenance and development of endometriosis...
February 7, 2018: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29413772/increasing-the-safety-of-minimally-invasive-hallux-surgery-an-anatomical-study-introducing-the-clock-method
#16
Francesc Malagelada, Miki Dalmau-Pastor, Betlem Fargues, Maria Cristina Manzanares-Céspedes, Fernando Peña, Jordi Vega
BACKGROUND: The purpose of this study is to describe a simple and reproducible method to localize the neurological structures at risk and to describe a safe zone for hallux minimally invasive surgery (MIS) procedures. METHODS: Ten fresh-frozen cadaveric feet were dissected to identify the dorsomedial digital nerve (DMDN) and the dorsolateral digital nerve (DLDN) of the first toe. Axial sections were performed at the sites of metatarsal osteotomies. We documented the position of the nerves with respect to the extensor hallucis longus (EHL) tendon using a clock method superimposed on the axial section RESULTS: The DMDN was found at an average of 26...
February 2018: Foot and Ankle Surgery: Official Journal of the European Society of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/29408856/quick-and-easy-sample-preparation-without-resin-embedding-for-the-bone-quality-assessment-of-fresh-calcified-bone-using-fourier-transform-infrared-imaging
#17
Hiromi Kimura-Suda, Masahiko Takahata, Teppei Ito, Tomohiro Shimizu, Kyosuke Kanazawa, Masahiro Ota, Norimasa Iwasaki
Fourier transform infrared (FTIR) imaging is a powerful tool for the assessment of bone quality; however, it requires the preparation of thin bone sections. Conventional poly(methyl methacrylate) (PMMA) embedding for the preparation of sections takes more than two weeks and causes denaturation of the bone. Development of a quick and easy sample preparation technique without denaturation is needed for accurate clinical evaluation of fresh calcified bone using FTIR imaging. Frozen sectioning allows the quick and easy preparation of thin sections without denaturation, but it requires a substrate with good chemical resistance and improved heat shock resistance...
2018: PloS One
https://www.readbyqxmd.com/read/29403208/internal-quality-control-of-blood-products-an-experience-from-a-tertiary-care-hospital-blood-bank-from-southern-pakistan
#18
Sadia Sultan, Hasan Abbas Zaheer, Usman Waheed, Mohammad Amjad Baig, Asma Rehan, Syed Mohammed Irfan
INTRODUCTION: Internal quality control (IQC) is the backbone of quality assurance program. In blood banking, the quality control of blood products ensures the timely availability of a blood component of high quality with maximum efficacy and minimal risk to potential recipients. The main objective of this study is to analyze the IQC of blood products as an indicator of our blood bank performance. METHODS: An observational cross-sectional study was conducted at the blood bank of Liaquat National Hospital and Medical College, from January 2014 to December 2015...
January 2018: Journal of Laboratory Physicians
https://www.readbyqxmd.com/read/29403162/intraoperative-cytology-of-ovarian-neoplasms-with-an-attempt-to-grade-epithelial-tumors
#19
Sangita Bohara, Shyama Jain, Nita Khurana, Darilin M Shangpliang, Swapnil Agarwal, Gauri Gandhi
Background: Intraoperative cytology (IOC) is a simple and quick technique with excellent preservation of cellular details. In the present study, we have evaluated the role of IOC by various methods of smear preparation and compared it with frozen section diagnosis. A scoring system was followed for epithelial tumors for characterization and grading on the basis of cellularity, pattern, nuclear, cytoplasmic features, and background details. Materials and Methods: The study was conducted during a time span of 2 years in total 48 cases of ovarian tumors...
January 2018: Journal of Cytology
https://www.readbyqxmd.com/read/29396855/use-of-a-novel-1-hour-protocol-for-rapid-frozen-section-immunocytochemistry-in-a-case-of-squamous-cell-carcinoma-treated-with-mohs-micrographic-surgery
#20
K Sinha, F Ali, G Orchard, W Rickaby, M Shams, R Mallipeddi, R Patalay
For squamous cell carcinoma (SCC) treated using Mohs micrographic surgery (MMS), interpretation of haematoxylin and eosin-stained frozen sections can be challenging. In these situations, ancillary use of immunostaining is a useful tool for the Mohs surgeon. However, use of immunostaining in MMS laboratories is limited, mainly because current manual immunostaining platforms are subject to operator error, and automated immunostaining, albeit accurate, is too slow for inclusion in MMS. In this report, we describe a novel 1-hour protocol for rapid frozen section immunocytochemistry, using the pancytokeratin markers AE1/AE3...
February 3, 2018: Clinical and Experimental Dermatology
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