Pasquale Vergara, Iside Scarfò, Antonio Esposito, Caterina Colantoni, Anna Palmisano, Savino Altizio, Giulio Falasconi, Luigi Pannone, Elisabetta Lapenna, Simone Gulletta, Ottavio Alfieri, Alessandro Castiglioni, Francesco Maisano, Michele De Bonis, Paolo Della Bella, Giovanni La Canna
BACKGROUND: Myxomatous mitral valve prolapse (MVP) and mitral-annular disjunction (Barlow disease) are at-risk for ventricular arrhythmias (VA). Fibrosis involving the papillary muscles and/or the infero-basal left ventricular (LV) wall was reported at autopsy in sudden cardiac death (SCD) patients with MVP. OBJECTIVES: We investigated the electrophysiological substrate subtending VA in MVP patients with Barlow disease phenotype. METHODS: Twenty-three patients with VA were enrolled, including five with syncope and 4 with a history of SCD...
October 19, 2021: Journal of Cardiovascular Electrophysiology