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https://www.readbyqxmd.com/read/29229170/care-of-the-pediatric-patient-on-chronic-dialysis
#1
REVIEW
Annabelle N Chua, Bradley A Warady
Optimal care of the pediatric end-stage renal disease (ESRD) patient on chronic dialysis is complex and requires multidisciplinary care as well as patient/caregiver involvement. The dialysis team, along with the family and patient, should all play a role in choosing the dialysis modality which best meets the patient's needs, taking into account special considerations and management issues that may be particularly pertinent to children who receive peritoneal dialysis or hemodialysis. Meticulous attention to dialysis adequacy in terms of solute and fluid removal, as well as to a variety of clinical manifestations of ESRD, including anemia, growth and nutrition, chronic kidney disease-mineral bone disorder, cardiovascular health, and neurocognitive development, is essential...
November 2017: Advances in Chronic Kidney Disease
https://www.readbyqxmd.com/read/29227948/points-of-attention-in-designing-tools-for-regional-brownfield-prioritization
#2
Elsa Limasset, Lisa Pizzol, Corinne Merly, Annette M Gatchett, Cécile Le Guern, Stanislav Martinát, Petr Klusáček, Stephan Bartke
The regeneration of brownfields has been increasingly recognized as a key instrument in sustainable land management, since free developable land (or so called "greenfields") has become a scare and more expensive resource, especially in densely populated areas. However, the complexity of these sites requires considerable efforts to successfully complete their revitalization projects, thus requiring the development and application of appropriate tools to support decision makers in the selection of promising sites where efficiently allocate the limited financial resources...
December 8, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29226229/subspecialisation-in-emergency-radiology-proposal-for-a-harmonised-european-curriculum
#3
M G Wagner, M R Fischer, M Scaglione, U Linsenmaier, G Schueller, F H Berger, E Dick, R Basilico, M Stajgis, C Calli, S Vaidya, Stefan Wirth
Introduction: Radiology plays a crucial role in the emergency care setting by delivering early and precise diagnoses under pressure of time, right at the beginning of patient treatment. Although there is a need for postgraduate education in emergency radiology, most of the national bodies responsible do not offer it in a uniform fashion and a general proof of qualification is missing in Europe. Therefore, the European Society of Radiology (ESR) has founded the (Sub-)Society of Emergency Radiology (ESER), prompting them to develop a European curriculum...
2017: GMS Journal for Medical Education
https://www.readbyqxmd.com/read/29215810/pediatric-deaths-attributed-to-complex-chronic-conditions-over-10-years-in-korea-evidence-for-the-need-to-provide-pediatric-palliative-care
#4
Min Sun Kim, Nam Gu Lim, Hyun Joo Kim, Chohee Kim, Jin Yong Lee
BACKGROUND: Pediatric palliative care (PPC) is the active total care of children suffering from life-threatening illnesses. Palliative care includes symptom management, psychosocial support, and end-of-life care. Despite significant advances in disease diagnosis and treatment, resources for PPC of children with serious illnesses are limited in Korea. This study aimed to investigate the scale, time trends, disease composition, regional distribution, and unmet needs of children dying from complex chronic conditions (CCCs)...
January 1, 2018: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/29211758/rubus-a-compiler-for-seamless-and-extensible-parallelism
#5
Muhammad Adnan, Faisal Aslam, Zubair Nawaz, Syed Mansoor Sarwar
Nowadays, a typical processor may have multiple processing cores on a single chip. Furthermore, a special purpose processing unit called Graphic Processing Unit (GPU), originally designed for 2D/3D games, is now available for general purpose use in computers and mobile devices. However, the traditional programming languages which were designed to work with machines having single core CPUs, cannot utilize the parallelism available on multi-core processors efficiently. Therefore, to exploit the extraordinary processing power of multi-core processors, researchers are working on new tools and techniques to facilitate parallel programming...
2017: PloS One
https://www.readbyqxmd.com/read/29211294/single-cell-analysis-using-hyperspectral-imaging-modalities
#6
Nishir Mehta, Shahensha Shaik, Ram Devireddy, Manas Gartia
Almost a decade ago, Hyperspectral Imaging (HSI) was employed by the NASA in satellite imaging applications such as remote sensing technology. This technology has since been extensively used in the exploration of minerals, agricultural purposes, water resources, and urban development needs. Due to recent advancements in optical re-construction and imaging, HSI can now be appliedtranslated down to micro- and nano-meter scales possibly allowing for exquisite control and analysis of single cell to complex biological systems...
December 6, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/29208410/application-of-heat-compensation-calorimetry-to-an-e-coli-fed-batch-process
#7
Matthias Müller, Wolfram Meusel, Ute Husemann, Gerhard Greller, Matthias Kraume
The application of biocalorimetry to fermentation processes offers advantageous insights, while being less complex compared to other,sophisticated PAT solutions. Although the general concept is established,calorimetric methods vary in detail. In this work, a special approach,called heat compensation calorimetry, was applied to an E. coli fed-batch process. Much work has been done for batch processes, proving the validity and accuracy of this calorimetric mode. However, the adaption of this strategy to fed-batch processes has some implications...
December 2, 2017: Journal of Biotechnology
https://www.readbyqxmd.com/read/29207379/practical-recommendations-of-the-obesity-management-task-force-of-the-european-association-for-the-study-of-obesity-for-the-post-bariatric-surgery-medical-management
#8
Luca Busetto, Dror Dicker, Carmil Azran, Rachel L Batterham, Nathalie Farpour-Lambert, Martin Fried, Jøran Hjelmesæth, Johann Kinzl, Deborah R Leitner, Janine M Makaronidis, Karin Schindler, Hermann Toplak, Volkan Yumuk
Bariatric surgery is today the most effective long-term therapy for the management of patients with severe obesity, and its use is recommended by the relevant guidelines of the management of obesity in adults. Bariatric surgery is in general safe and effective, but it can cause new clinical problems and is associated with specific diagnostic, preventive and therapeutic needs. For clinicians, the acquisition of special knowledge and skills is required in order to deliver appropriate and effective care to the post-bariatric patient...
December 6, 2017: Obesity Facts
https://www.readbyqxmd.com/read/29205923/home-based-interval-training-increases-endurance-capacity-in-adults-with-complex-congenital-heart-disease
#9
Camilla Sandberg, Magnus Hedström, Karin Wadell, Mikael Dellborg, Anders Ahnfelt, Anna-Klara Zetterström, Amanda Öhrn, Bengt Johansson
OBJECTIVE: The beneficial effects of exercise training in acquired heart failure and coronary artery disease are well known and have been implemented in current treatment guidelines. Knowledge on appropriate exercise training regimes for adults with congenital heart disease is limited, thus further studies are needed. The aim of this study was to examine the effect of home-based interval exercise training on maximal endurance capacity and peak exercise capacity. DESIGN: Randomized controlled trial...
December 4, 2017: Congenital Heart Disease
https://www.readbyqxmd.com/read/29204825/stem-cell-microenvironments-and-beyond
#10
Alexander Birbrair
Endogenous stem cells are indispensable to keep tissue homeostasis due to their unique ability to generate more specialized cell types in an organized way depending on the body needs. Precise control over stem cell differentiation is essential for organogenesis and tissue homeostasis. Stem cells reside in specialized microenvironments, also called niches, which maintain them in an undifferentiated and self-renewing state. The cellular and molecular mechanisms of stem cell maintenance are key to the regulation of homeostasis and likely contribute to several disorders when altered during adulthood...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29202586/pharmacological-treatments-available-for-the-management-of-underactive-bladder-in-neurological-conditions
#11
Seyedeh-Sanam Ladi-Seyedian, Behnam Nabavizadeh, Lida Sharifi-Rad, Abdol-Mohammad Kajbafzadeh
Underactive bladder (UAB) is a common cause of lower urinary tract dysfunction which has an increasing incidence with aging. It is characterized as an incompetent detrusor contraction with reduced strength and/or duration to completely empty the bladder. UAB is observed in both men and women. The exact definition, classification, and pathophysiological mechanism responsible for UAB is still debatable, however neurologic, myogenic, and iatrogenic causes are explained. The symptom complex related to UAB includes hesitancy, diminished sensation of bladder filling, a slow urinary stream, increased post-void residue, and etc...
December 5, 2017: Expert Review of Clinical Pharmacology
https://www.readbyqxmd.com/read/29201772/managing-encephalopathy-in-the-outpatient-setting
#12
REVIEW
Tarana Gupta, Sahaj Rathi, Radha K Dhiman
In cirrhosis of liver, hepatic encephalopathy (HE) has an important impact on health-related quality of life. It is important to define whether HE is episodic, recurrent, or persistent; types A, B, or C; overt HE or covert HE; and spontaneous or precipitated. The overt HE is clinically evident and needs hospitalization. Nonabsorbable disaccharides, rifaximin, and probiotics are proven to be useful in the treatment of overt HE. Covert HE includes both minimal HE and grade I HE. It is not apparent on routine clinical examination...
January 2017: Euroasian Journal of Hepato-Gastroenterology
https://www.readbyqxmd.com/read/29200799/improving-police-interventions-during-mental-health-related-encounters-past-present-and-future
#13
Jennifer D Wood, Amy C Watson
There are calls across America for police to re-imagine themselves as "guardians" rather than "warriors" in the performance of their innumerable duties. The contentious history of police attitudes and practices surrounding encounters with people affected by mental illnesses can be understood through the lens of this wider push toward guardianship. At least as far back as the de-institutionalization of mental health care and the profound lack of community-based resources to fill service deficits, the role of police as mental health interventionists has been controversial and complex...
2017: Policing & Society
https://www.readbyqxmd.com/read/29198090/-co-occurring-schizophrenia-and-substance-use-disorder-etiological-theories-and-challenges-in-israel
#14
REVIEW
Sharon Florentin, Sergey Raskin
A sizeable number of patients suffering from psychotic disorders, particularly schizophrenia, are also diagnosed with substance use disorder (SUD). These dual diagnosis (DD) patients are considered very difficult to treat and differ in some of their characteristics from patients with schizophrenia or SUD exclusively. They have a worse prognosis and require more complex treatment which needs to be integrated for both of the disorders. In Israel there is a lack of training, professionals and institutions specializing in treatment for this population...
November 2017: Harefuah
https://www.readbyqxmd.com/read/29197381/cross-cultural-validation-and-psychometric-testing-of-the-norwegian-version-of-the-teamstepps%C3%A2-teamwork-perceptions-questionnaire
#15
Randi Ballangrud, Sissel Eikeland Husebø, Marie Louise Hall-Lord
BACKGROUND: Teamwork is an integrated part of today's specialized and complex healthcare and essential to patient safety, and is considered as a core competency to improve twenty-first century healthcare. Teamwork measurements and evaluations show promising results to promote good team performance, and are recommended for identifying areas for improvement. The validated TeamSTEPPS® Teamwork Perception Questionnaire (T-TPQ) was found suitable for cross-cultural validation and testing in a Norwegian context...
December 2, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/29193746/dual-functional-dextran-peg-hydrogel-as-an-antimicrobial-biomedical-material
#16
Lei Wang, Xin Li, Tianyu Sun, Yung-Hao Tsou, Hong Chen, Xiaoyang Xu
Microbial infections continually present a major worldwide public healthcare threat, particularly in instances of impaired wound healing and biomedical implant fouling. The development of new materials with the desired antimicrobial property to avoid and treat wound infection is urgently needed in wound care management. This study reports a novel dual-functional biodegradable dextran-poly(ethylene glycol) (PEG) hydrogel covalently conjugated with antibacterial Polymyxin B and Vancomycin (Vanco). The hydrogel is designed as a specialized wound dressing that eradicates existing bacteria and inhibits further bacteria growth, while, ameliorating the side effects of antibiotics and accelerating tissue repair and regeneration...
November 29, 2017: Macromolecular Bioscience
https://www.readbyqxmd.com/read/29192752/graphene-oxide-polydimethylsiloxane-based-lab-on-a-chip-platform-for-heavy-metals-preconcentration-and-electrochemical-detection
#17
Andrzej Chałupniak, Arben Merkoçi
Herein we present the application of a novel graphene oxide - polydimethylsiloxane (GO-PDMS) composite in reversible adsorption/desorption including detection of heavy metals. GO-PDMS was fabricated by simple blending of GO with silicon monomer in presence of tetrahydrofuran, followed by polymerization initiated upon curing agent addition. We found GO concentration, curing agent concentration, pH and contact time among the most important factors affecting the adsorption of Pb(II) used as a model heavy metal...
December 1, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29192737/dreams-and-illusions-in-adolescents-with-terminal-cancer
#18
Laura Veneroni, Andrea Ferrari, Tullio Proserpio, Elena Pagani Bagliacca, Marta Podda, Maura Massimino, Carlo Alfredo Clerici
Being diagnosed with cancer in adolescence generally has important emotional consequences: adolescent cancer patients need to be seen as special cases with particular medical and psychosocial needs. This is especially true when a young patient is faced with a progressive, incurable disease. Herein, we report the story of a 17-year-old girl with a metastatic refractory soft tissue sarcoma who tells her dream to the psychologist of the ward. Telling this narrative is the opportunity to discuss the complex topic of how adolescent cancer patients adapt to the terminal stage of their disease; for example, the patient needs to talk to someone about their fear of dying; the healthcare operators need to be able properly listen and communicate; the patient's trust in the future despite their clinical condition; the necessity to leave space for hope; the useful role of the imagination sphere; the issue of whether and how to tell a person who is terminally ill the truth about their condition...
November 21, 2017: Tumori
https://www.readbyqxmd.com/read/29185791/recovery-of-anthocyanins-using-membrane-technologies-a-review
#19
Julia Martín, Enrique Jacobo Díaz Montaña, Agustin G Asuero
Anthocyanins are naturally occurring polyphenolic compounds and give many flowers, fruits and vegetable their orange, red, purple, and blue colors. Besides their color attributes, anthocyanins have received much attention in recent years due to the growing evidence of their antioxidant capacity and health benefits on humans. However, these compounds usually occur in low concentrations in mixtures of complex matrices, and therefore large-scale harvesting is needed to obtain sufficient amounts for their practical usage...
November 29, 2017: Critical Reviews in Analytical Chemistry
https://www.readbyqxmd.com/read/29175646/communication-of-genetic-information-to-families-with-inherited-rhythm-disorders
#20
Charlotte Burns, Cynthia James, Jodie Ingles GradDipGenCouns
The dynamic nature of the electrical activity of the heart and ongoing challenges in the diagnostics of inherited heart rhythm disorders mean genetic information can be a vital aspect of family management. Communication of genetic information is complex and the responsibility to convey this information to the family lies with the proband. Current practice falls short, requiring additional support from the clinician and multidisciplinary team. Communication is a two-part iterative process, reliant on both the probands understanding and their ability to effectively communicate with relatives...
November 23, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
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