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https://www.readbyqxmd.com/read/29452786/preliminary-results-of-a-single-arm-pilot-study-to-assess-the-safety-and-efficacy-of-visnadine-prenylflavonoids-and-bovine-colostrum-in-postmenopausal-sexually-active-women-affected-by-vulvovaginal-atrophy
#1
Antonio Simone Laganà, Salvatore Giovanni Vitale, Lily Stojanovska, Irene Lambrinoudaki, Vasso Apostolopoulos, Benito Chiofalo, Laura Rizzo, Francesca Basile
This single-arm pilot study enrolled 47 post-menopausal women affected by vulvovaginal atrophy (VVA). The Vaginal Health Index Score (VHIS) was evaluated for all women and all completed the Female Sexual Function Index (FSFI) questionnaire at baseline (T0) and after 15 days of vaginal cream treatment with one application per day (T1). Following treatment there was a significant improvement in all VHIS parameters and total score (p < 0.0001). Similarly, there was a significant improvement on four FSFI domains (lubrication, orgasm, satisfaction and pain) and total score (p = 0...
March 2018: Maturitas
https://www.readbyqxmd.com/read/29442353/the-effect-of-vitamin-d-supplementation-on-sexual-functioning-and-depressive-symptoms-in-young-women-with-low-vitamin-d-status
#2
Robert Krysiak, Anna Szwajkosz, Bogdan Marek, Bogusław Okopień
BACKGROUND: Hypovitaminosis D is associated with abnormal female sexual functioning. The aim of our study was to assess whether vitamin D supplementation affects sexual functioning and depressive symptoms in young women with low vitamin D status. METHODS: The study included 47 women with vitamin D deficiency or insufficiency. All women with vitamin D deficiency were treated with oral vitamin D, while women with vitamin D insufficiency were either treated with vitamin D or left untreated...
February 14, 2018: Endokrynologia Polska
https://www.readbyqxmd.com/read/29402732/female-sexual-dysfunction-a-systematic-review-of-outcomes-across-various-treatment-modalities
#3
REVIEW
James M Weinberger, Justin Houman, Ashley T Caron, Jennifer Anger
BACKGROUND: Female sexual dysfunction (FSD) is a highly prevalent condition. Nevertheless, the scientific literature has only recently begun to accumulate evidence for treatment modalities that address the underlying etiologies of FSD. AIM: The purpose of this systematic review is to elucidate what treatments are effective across the various symptom complexes of FSD. METHODS: Utilizing Meta-analysis of Observational Studies in Epidemiology guidelines, we conducted a systematic review of PubMed, EMBASE, clinicaltrials...
February 3, 2018: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/29396021/sexual-inhibition-is-a-vulnerability-factor-for-orgasm-problems-in-women
#4
Inês M Tavares, Ellen T M Laan, Pedro J Nobre
BACKGROUND: The differential role of psychological traits in the etiology and maintenance of female orgasm difficulties is yet to be consistently established. AIM: To investigate the contribution of different psychological trait features (personality, sexual inhibition and excitation, and sexual beliefs) to predict female orgasm and to assess the degree to which these dispositional factors moderate the association between sexual activity and orgasm occurrence in a large community sample of Portuguese women...
January 25, 2018: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/29383415/autologous-fibroblast-seeded-amnion-for-reconstruction-of-neo-vagina-in-male-to-female-reassignment-surgery
#5
Kamal Seyed-Forootan, Hamid Karimi, Nazilla-Sadat Seyed-Forootan
BACKGROUND: Plastic surgeons have used several methods for the construction of neo-vaginas, including the utilization of penile skin, free skin grafts, small bowel or recto-sigmoid grafts, an amnion graft, and cultured cells. PURPOSE: The aim of this study is to compare the results of amnion grafts with amnion seeded with autograft fibroblasts. MATERIALS AND METHODS: Over 8 years, we compared the results of 24 male-to-female transsexual patients retrospectively based on their complications and levels of satisfaction...
January 30, 2018: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/29370358/vaginal-laxity-sexual-distress-and-sexual-dysfunction-a-cross-sectional-study-in-a-plastic-surgery-practice
#6
Ali A Qureshi, Ketan Sharma, Melissa Thornton, Terence M Myckatyn, Marissa M Tenenbaum
Background: Sexual health issues can be characterized by vaginal laxity (VL), sexual distress, and sexual dysfunction. The epidemiology of these issues in plastic surgery patients, and especially breast cancer survivors, remains poorly understood. Objectives: To prospectively assess sexual health issues in a plastic surgery patient population with and without breast cancer. Methods: A prospective cohort study was created in our practice from June to August 2017 with administration of a survey including the vaginal laxity questionnaire (VLQ), female sexual distress scale-revised (FSDS-R), and female sexual function index (FSFI)...
January 23, 2018: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/29349764/sexual-function-post-breast-cancer
#7
Lauren Streicher, James A Simon
The consequences of estrogen deprivation and therapeutic interventions such as radiation, chemotherapy and surgery have a significant negative impact on libido, sexual arousal, orgasmic function and the ability to have pleasurable intercourse. Evaluation and treatment of female sexual dysfunction is a significant unmet need in the breast cancer survivor in spite of the availability of safe and effective treatments.
2018: Cancer Treatment and Research
https://www.readbyqxmd.com/read/29285596/differential-diagnostics-of-female-sexual-fluids-a-narrative-review
#8
REVIEW
Zlatko Pastor, Roman Chmel
INTRODUCTION AND HYPOTHESIS: Women expel various kinds of fluids during sexual activities. These are manifestations of sexual arousal and orgasm or coital incontinence. This study is aimed at suggesting a diagnostic scheme to differentiate among these phenomena. METHODS: Web of Science and Ovid (MEDLINE) databases were systematically searched from 1950 to 2017 for articles on various fluid expulsion phenomena in women during sexual activities, which contain relevant information on sources and composition of the expelled fluids...
December 28, 2017: International Urogynecology Journal
https://www.readbyqxmd.com/read/29278235/role-of-hormones-in-hypoactive-sexual-desire-disorder-and-current-treatment
#9
Ahmed AlAwlaqi, Houda Amor, Mohamed E Hammadeh
Over the decades, female sexual dysfunction (FSD) has grown to be an increasingly potential problem that complicates the quality of life among women. In the current review, FSD refers to recurrent and persistent problems with sexual orgasm, desire, or response. One of the most common subtypes of FSD that has evoked increased research interest in the scientific community is hyposexuality. Today, there is a consensus that hyposexuality is a multifactorial condition that manifests with reduced sexual desire resulting in significant interpersonal distress...
December 15, 2017: Journal of the Turkish German Gynecological Association
https://www.readbyqxmd.com/read/29230716/efficacy-and-tolerability-of-a-spray-formulation-containing-visnadine-in-women-self-reporting-sexual-symptoms-a-randomized-double-blind-placebo-controlled-pilot-study
#10
R Bernorio, S Piloni, G Mori, A Prunas, D Bosoni, R E Nappi
PURPOSE: The aim of this pilot, double-blind, randomized, placebo-controlled study, was to evaluate both the efficacy and the tolerability of a formulation for vulvar application containing Visnadine, a natural extractive substance with vasoactive properties, (ReFeel® spray, IDI Integratori Dietetici Italiani S.r.l., Italy) in women self-reporting sexual symptoms. METHODS: Sixty women (age range 18-60 years) volunteered to test the product against placebo (PL): Two puffs in the vulvar area, 10 min before sexual stimulation, for 30 days and for a minimum of six times...
December 11, 2017: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/29209890/a-longitudinal-assessment-of-associations-between-women-s-tendency-to-pretend-orgasm-orgasm-function-and-intercourse-related-pain-in-different-partner-relationship-constellations
#11
Patrick Jern, Outi Hakala, Antti Kärnä, Annika Gunst
The aim of the present study was to investigate how women's tendency to pretend orgasm during intercourse is associated with orgasm function and intercourse-related pain, using a longitudinal design where temporal stability and possible causal relationships could be modeled. The study sample consisted of 1421 Finnish women who had participated in large-scale population-based data collections conducted at two time points 7 years apart. Pretending orgasm was assessed for the past 4 weeks, and orgasm function and pain were assessed using the Female Sexual Function Index for the past 4 weeks...
December 5, 2017: Archives of Sexual Behavior
https://www.readbyqxmd.com/read/29198504/female-sexual-dysfunction-medical-and-psychological-treatments-committee-14
#12
Sheryl A Kingsberg, Stanley Althof, James A Simon, Andrea Bradford, Johannes Bitzer, Joana Carvalho, Kathryn E Flynn, Rossella E Nappi, Jennifer B Reese, Roya L Rezaee, Leslie Schover, Jan L Shifrin
INTRODUCTION: Since the millennium we have witnessed significant strides in the science and treatment of female sexual dysfunction (FSD). This forward progress has included (i) the development of new theoretical models to describe healthy and dysfunctional sexual responses in women; (ii) alternative classification strategies of female sexual disorders; (iii) major advances in brain, hormonal, psychological, and interpersonal research focusing on etiologic factors and treatment approaches; (iv) strong and effective public advocacy for FSD; and (v) greater educational awareness of the impact of FSD on the woman and her partner...
December 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/29197397/the-heat-goes-away-sexual-disorders-of-married-women-with-female-genital-mutilation-cutting-in-kenya
#13
Tammary Esho, Samuel Kimani, Isaac Nyamongo, Violet Kimani, Samuel Muniu, Christine Kigondu, Patrick Ndavi, Jaldesa Guyo
BACKGROUND: Female genital mutilation/cutting (FGM/C) has been implicated in sexual complications among women, although there is paucity of research evidence on sexual experiences among married women who have undergone this cultural practice. The aim of this study was to investigate the sexual experiences among married women in Mauche Ward, Nakuru County. METHODS: Quantitative and qualitative data collection methods were used. Quantitative data were obtained from 318 married women selected through multistage sampling...
December 2, 2017: Reproductive Health
https://www.readbyqxmd.com/read/29182498/effect-of-single-session-cryogen-cooled-monopolar-radiofrequency-therapy-on-sexual-function-in-women-with-vaginal-laxity-the-viveve-i-trial
#14
Michael Krychman, Christopher G Rowan, Bruce B Allan, Scott Durbin, Ashley Yacoubian, Deborah Wilkerson
OBJECTIVE: This subanalysis of the VIVEVE I trial aimed to evaluate the impact of cryogen-cooled monopolar radiofrequency (CMRF) therapy, for the treatment of vaginal laxity, on the domains of sexual function included in the Female Sexual Function Index (FSFI). MATERIALS AND METHODS: The VIVEVE I clinical trial was prospective, randomized, single-blind, and Sham-controlled. Nine clinical study centers in Canada, Italy, Spain, and Japan were included. This subanalysis included premenopausal women with self-reported vaginal laxity who had ≥1 term vaginal delivery and a baseline FSFI total score ≤26...
November 28, 2017: Journal of Women's Health
https://www.readbyqxmd.com/read/29180795/hypertension-and-obesity-comorbidities-increases-coronary-risk-affects-domains-of-sexual-function-and-sexual-quality-of-life
#15
H Alidu, W K B A Owiredu, N Amidu, C K Gyasi-Sarpong, P P M Dapare, A T Bawah, C Obirikorang, A T Luuse
About 25% of the world's adult population suffers from arterial hypertension with about 1.5 billion estimated to develop hypertension by 2025. Hypertensive patients have been reported to have a higher risk of developing diabetes and sexual dysfunction. Hypertension have been linked with lubricative and orgasmic difficulties in females, as wel as ED and vascular disease in men. Obesity has also been linked to ED in diabetic males as well as several aspects of female sexuality. Hypertension and obesity are closely related, each occurring in greater frequency with the other, it is only logical to think that comorbidities of obesity and hypertension could increase the risk of cardiovascular disease and SD...
November 27, 2017: International Journal of Impotence Research
https://www.readbyqxmd.com/read/29176500/a-pilot-study-of-a-topical-intervention-for-treatment-of-female-sexual-dysfunction
#16
Adel Abdel-Wadood Gomaa, Nermeen M Abdel Aziz, Romany H Thabet, Howieda A Fouly, Sara H Altellawy, Ghada A Gomaa
PURPOSE/BACKGROUND: Many investigators reported that pharmacological treatment of female sexual dysfunction (FSD) has been a promising field yet to be explored. The purpose of this pilot study was to investigate the efficacy and safety of a topical cream containing small concentrations of three vasodilators with different mechanisms of action in treating FSD. METHODS: In this randomized, controlled pilot trial, premenopausal (n = 30) and postmenopausal (n = 30) cases of 21- to 62-year age range with FSD were allocated randomly into 15 given placebo or 15 given active cream in each group...
February 2018: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/29171484/-sexual-functioning-and-sexual-dysfunction-in-women-with-infertility
#17
N N Stenyaeva, D F Chritinin, A A Chausov, G T Sukhikh
AIM: To study sexual dysfunction and assess the need in sexological care to improve quality of life of women with infertility. MATERIAL AND METHODS: Sexual functioning was studied in 329 women with infertility and 722 women who underwent an outpatient gynecological examination using a clinical interview and the Female Sexual Function Index (FSFI). RESULTS: In 24.01% of women with infertility, the total FSFI score was correlated with the presence of clinically relevant disorders...
2017: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/29117756/long-term-postpartum-effect-of-severe-maternal-morbidity-on-sexual-function
#18
Mohd Noor Norhayati, Mohd Azman Yacob
There was limited knowledge on the sexual function in women who have survived severe obstetric complications. The aim of this study was to compare the level of sexual functioning among women with and without severe morbidity at six months postpartum and to identify the factors associated with sexual function scores of women. A prospective double-cohort study design was applied at two tertiary hospitals over a six-month period. Postpartum women with and without severe maternal morbidity were selected as the exposed and the non-exposed group, respectively...
July 2017: International Journal of Psychiatry in Medicine
https://www.readbyqxmd.com/read/29110806/masturbation-to-orgasm-stimulates-the-release-of-the-endocannabinoid-2-arachidonoylglycerol-in-humans
#19
Johannes Fuss, Laura Bindila, Klaus Wiedemann, Matthias K Auer, Peer Briken, Sarah V Biedermann
BACKGROUND: Endocannabinoids are critical for rewarding behaviors such as eating, physical exercise, and social interaction. The role of endocannabinoids in mammalian sexual behavior has been suggested because of the influence of cannabinoid receptor agonists and antagonists on rodent sexual activity. However, the involvement of endocannabinoids in human sexual behavior has not been studied. AIM: To investigate plasma endocannabinoid levels before and after masturbation in healthy male and female volunteers...
November 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/29110805/a-population-based-epidemiologic-study-of-female-sexual-dysfunction-risk-in-mainland-china-prevalence-and-predictors
#20
Chunni Zhang, Jiali Tong, Lan Zhu, Lei Zhang, Tao Xu, Jinghe Lang, Yu Xie
BACKGROUND: Epidemiologic data on female sexual dysfunction in China are sparse. AIM: To assess the prevalence of risk of female sexual dysfunction in mainland China and its regional and sociodemographic variations and physiologic, pathologic, and behavioral risk factors. METHODS: A survey of the general female population was conducted in mainland China from February 2014 through January 2016. Women were randomly selected using multistage, stratified, cluster sampling...
November 2017: Journal of Sexual Medicine
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