James P Franciosi, Morris Gordon, Vassiliki Sinopoulou, Evan S Dellon, Sandeep K Gupta, Craig C Reed, Carolina Gutiérrez-Junquera, Rajitha D Venkatesh, Elizabeth A Erwin, Abdullah Egiz, Assem Elleithy, Edward B Mougey
BACKGROUND: Eosinophilic esophagitis (EoE) is a chronic antigen-mediated eosinophilic inflammatory disease isolated to the esophagus. As a clinicopathologic disorder, a diagnosis of EoE requires a constellation of clinical symptoms of esophageal dysfunction and histologic findings (at least 15 eosinophils/high-powered microscope field (eos/hpf)). Current guidelines no longer require the failure of response to proton pump inhibitor medications to establish a diagnosis of EoE, but continue to suggest the exclusion of other etiologies of esophageal eosinophilia...
July 20, 2023: Cochrane Database of Systematic Reviews