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tumor enviroment

Zoran Culig, Martin Puhr
Interleukin (IL)-6 is a pro-inflammatory cytokine that is expressed in prostate tumors and in the stromal tumor micro-enviroment. It is known to regulate proliferation, apoptosis, angiogenesis, and differentiation. The signaling pathway of Janus kinase and signal transducer and activator of transcription (STAT)3, which is activated by IL-6, is in the focus of scientific investigations for improved treatment approaches. Different effects of IL-6 and/or STAT3 on tumor cell growth have been observed in human and murine prostate cancer (PCa) models...
March 16, 2017: Molecular and Cellular Endocrinology
Andrzej Kwolek, Krystyna Lewicka
Background. Patients undergoing rehabilitation in rehablitation wards particulary those focused on geriatry or neurology are expose to falls.It is connected with advanced age and also their illness essence.<br /> This kind of falls appears to be very important problem because some of them could lead to severe physical contusion or loss of trust in own ability and fear against the activities.<br /> The aim of this study was to analyse incidence of falls in all groups of patients rehabilited in the ward, the causes of falls and consequences of them and estabilshing the preventional rules for hemiparetic patients after stroke or operated brain's tumors...
October 30, 2002: Ortopedia, Traumatologia, Rehabilitacja
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