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https://www.readbyqxmd.com/read/28330798/knee-osteoarthritis-degenerative-meniscal-lesion-and-osteonecrosis-of-the-knee-can-a-simple-gait-test-direct-us-to-a-better-clinical-diagnosis
#1
Ronen Debi, Avi Elbaz, Amit Mor, Gadi Kahn, Bezalel Peskin, Yiftah Beer, Gabriel Agar, Guy Morag, Ganit Segal
INTRODUCTION: The purpose of the current study was to compare the gait patterns in patients with three differing knee pathologies - knee osteoarthritis (OA), degenerative meniscal lesion (DML) and spontaneous osteonecrosis of the knee (SONK) and a group of healthy controls. HYPOTHESIS: A simple gait test will detect differences between different knee pathologies. MATERIAL AND METHODS: Forty-seven patients with bilateral knee OA, 47 patients with DML, 28 patients with SONK and 27 healthy controls were included in this analysis...
March 19, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/28302305/absolute-or-relative-stability-in-minimal-invasive-plate-osteosynthesis-of-simple-distal-meta-or-diaphyseal-tibia-fractures
#2
R Wenger, F Oehme, J Winkler, S M Perren, R Babst, F J P Beeres
INTRODUCTION: Minimal invasive plate osteosynthesis in simple distal meta or diaphyseal tibia fractures can be applied using absolute (lag screw and neutralisation plate; LSN) or relative stability (bridge plate; BP). The primary aim of the study was to compare time to radiological union and time to full weight bearing in the two groups (LSN vs. BP). Reduction was performed either percutaneously or by a minimally open approach (mini open). Secondary aim was to analyse the number of complications between both groups...
March 6, 2017: Injury
https://www.readbyqxmd.com/read/28301644/association-of-body-mass-index-with-infectious-complications-in-free-tissue-transfer-for-head-and-neck-reconstructive-surgery
#3
Mohemmed N Khan, Jack Russo, John Spivack, Christopher Pool, Ilya Likhterov, Marita Teng, Eric M Genden, Brett A Miles
Importance: Elevated body mass index (BMI) has been proposed as a risk factor for morbidity and mortality among patients undergoing surgery. Conversely, an elevated BMI may confer a protective effect on perioperative morbidity. Objective: To examine whether an elevated BMI is an independent risk factor for perioperative and postoperative infectious complications after free tissue transfer in head and neck reconstructive surgery. Design, Setting, and Participants: This cohort study included patients undergoing major head and neck surgery requiring free tissue transfer at a tertiary care center...
March 16, 2017: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28286671/low-dose-ct-pulmonary-angiography-on-a-15-year-old-ct-scanner-a-feasibility-study
#4
Moritz Kaup, Tatjana Gruber-Rouh, Jan E Scholtz, Moritz H Albrecht, Andreas Bucher, Claudia Frellesen, Thomas J Vogl, Martin Beeres
BACKGROUND: Computed tomography (CT) low-dose (LD) imaging is used to lower radiation exposure, especially in vascular imaging; in current literature, this is mostly on latest generation high-end CT systems. PURPOSE: To evaluate the effects of reduced tube current on objective and subjective image quality of a 15-year-old 16-slice CT system for pulmonary angiography (CTPA). MATERIAL AND METHODS: CTPA scans from 60 prospectively randomized patients (28 men, 32 women) were examined in this study on a 15-year-old 16-slice CT scanner system...
December 2016: Acta Radiologica Open
https://www.readbyqxmd.com/read/28284416/using-the-beers-criteria-to-identify-potentially-inappropriate-medication-use-by-older-adult-dental-patients
#5
Daniel D Skaar, Heidi O'Connor
BACKGROUND: An aging population indicates that increasing numbers of older adults will seek oral health care and have multiple chronic conditions treated with a number of medications. The authors examined the Medicare Current Beneficiary Survey administrative data set to characterize potentially inappropriate medication (PIM) use by older adults visiting the dentist and related adverse experiences that may affect oral health care. METHODS: The authors used the 2015 Beers criteria to identify PIMs for older adults...
March 8, 2017: Journal of the American Dental Association
https://www.readbyqxmd.com/read/28275099/the-mediterranean-diet-score-is-more-strongly-associated-with-favorable-cardiometabolic-risk-factors-over-2-years-than-other-diet-quality-indexes-in-puerto-rican-adults
#6
Josiemer Mattei, Mercedes Sotos-Prieto, Sherman J Bigornia, Sabrina E Noel, Katherine L Tucker
Background: Multiple diet quality scores have been used to evaluate adherence to specific dietary recommendations or to consumption of healthful foods and nutrients. It remains unknown which score can more strongly predict longitudinal changes in cardiometabolic risk factors.Objective: We aimed to determine associations of 5 diet quality scores [AHA diet score (AHA-DS), Dietary Approaches to Stop Hypertension (DASH), Healthy Eating Index (HEI)-2005, Mediterranean diet score (MeDS), and Alternative Healthy Eating Index (AHEI)] with 2-y changes in cardiometabolic risk factors in adults 45-75 y old...
March 8, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28225055/alcoholic-beverage-preference-and-diabetes-incidence-across-europe-the-consortium-on-health-and-ageing-network-of-cohorts-in-europe-and-the-united-states-chances-project
#7
D Sluik, N Jankovic, M Hughes, M G O'Doherty, B Schöttker, W Drygas, O Rolandsson, S Männistö, J M Ordóñez-Mena, J Ferrieres, C Bamia, G de Gaetano, J C Kiefte-De Jong, O H Franco, I Sluijs, A M W Spijkerman, S Sans, S Eriksson, D Kromhout, A Trichopoulou, T Wilsgaard, H Brenner, K Kuulasmaa, T Laatikainen, S Söderberg, L Iacoviello, P Boffetta, F Kee, E J M Feskens
BACKGROUND/OBJECTIVES: It is unknown if wine, beer and spirit intake lead to a similar association with diabetes. We studied the association between alcoholic beverage preference and type 2 diabetes incidence in persons who reported to consume alcohol. SUBJECTS/METHODS: Ten European cohort studies from the Consortium on Health and Ageing: Network of Cohorts in Europe and the United States were included, comprising participant data of 62 458 adults who reported alcohol consumption at baseline...
February 22, 2017: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28146535/reflectance-mode-interferometric-near-infrared-spectroscopy-quantifies-brain-absorption-scattering-and-blood-flow-index-in-vivo
#8
Dawid Borycki, Oybek Kholiqov, Vivek J Srinivasan
Interferometric near-infrared spectroscopy (iNIRS) is a new technique that measures time-of-flight- (TOF-) resolved autocorrelations in turbid media, enabling simultaneous estimation of optical and dynamical properties. Here, we demonstrate reflectance-mode iNIRS for noninvasive monitoring of a mouse brain in vivo. A method for more precise quantification with less static interference from superficial layers, based on separating static and dynamic components of the optical field autocorrelation, is presented...
February 1, 2017: Optics Letters
https://www.readbyqxmd.com/read/28115442/effect-of-comorbidities-and-medications-on-frequency-of-primary-care-visits-among-older-patients
#9
Tina Hu, Neil D Dattani, Kelly Anne Cox, Bonnie Au, Leo Xu, Don Melady, Liisa Jaakkimainen, Rahul Jain, Jocelyn Charles
OBJECTIVE: To determine if comorbidities and high-risk medications affect the frequency of family physician visits among older patients. DESIGN: Retrospective chart review. SETTING: Academic family health team at Sunnybrook Health Sciences Centre in Toronto, Ont. PARTICIPANTS: Among patients aged 65 years and older who were registered patients of the family health team between July 1, 2013, and June 30, 2014, the 5% who visited their family physicians most frequently and the 5% who visited their family physicians least frequently were selected for the study (N = 265)...
January 2017: Canadian Family Physician Médecin de Famille Canadien
https://www.readbyqxmd.com/read/28092760/serum-brain-derived-neurotrophic-factor-and-stability-of-depressive-symptoms-in-coronary-heart-disease-patients-a-prospective-study
#10
Stella L Kuhlmann, Mira Tschorn, Volker Arolt, Katja Beer, Julia Brandt, Laura Grosse, Wilhelm Haverkamp, Jacqueline Müller-Nordhorn, Nina Rieckmann, Johannes Waltenberger, Katharina Warnke, Rainer Hellweg, Andreas Ströhle
OBJECTIVE: Brain-derived neurotrophic factor (BDNF) supports neurogenesis, angiogenesis, and promotes the survival of various cell types in the brain and the coronary system. Moreover, BDNF is associated with both coronary heart disease (CHD) and depression. The current study aims to investigate whether serum BDNF levels are associated with the course of depressive symptoms in CHD patients. METHODS: At baseline, N=225 CHD patients were enrolled while hospitalized...
December 23, 2016: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28045115/skeletal-related-events-significantly-impact-health-related-quality-of-life-in-metastatic-castration-resistant-prostate-cancer-data-from-prevail-and-affirm-trials
#11
F Saad, C Ivanescu, D Phung, Y Loriot, S Abhyankar, T M Beer, B Tombal, S Holmstrom
BACKGROUND: We investigated the impact of skeletal-related events (SREs) on health-related quality of life (HRQoL) in patients with metastatic castration-resistant prostate cancer (mCRPC) in phase III trials of enzalutamide versus placebo. METHODS: Patients with mCRPC experiencing at least one SRE during AFFIRM and PREVAIL were assessed for trajectory-adjusted mean change in HRQoL by first SRE using Functional Assessment of Cancer Therapy-Prostate (FACT-P; AFFIRM, three domains, and PREVAIL, nine domains) and EQ-5D (PREVAIL) instruments...
March 2017: Prostate Cancer and Prostatic Diseases
https://www.readbyqxmd.com/read/27919698/the-use-of-partially-hydrolysed-polyvinyl-alcohol-for-the-production-of-high-drug-loaded-sustained-release-pellets-via-extrusion-spheronisation-and-coating-in-vitro-and-in-vivo-evaluation
#12
G Verstraete, W De Jaeghere, J Vercruysse, W Grymonpré, V Vanhoorne, F Stauffer, T De Beer, A Bezuijen, J P Remon, C Vervaet
Partially hydrolysed polyvinyl alcohol (PVA) was evaluated as a pelletisation aid for the production of pellets with a high acetaminophen and metformin hydrochloride concentration (>70%, w/w). Mixtures with varying drug concentration and PVA/microcrystalline cellulose (MCC) ratios were processed via extrusion-spheronisation, either after addition of PVA as a dry powder or as an aqueous solution. Finally, high drug- loaded metformin pellets were coated with a methacrylic acid copolymer (Eudragit™ NM 30D) and evaluated for their sustained release potency in vitro and in vivo...
December 2, 2016: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/27861761/prediagnostic-alcohol-consumption-and-colorectal-cancer-survival-the-colon-cancer-family-registry
#13
Amanda I Phipps, Jamaica R Robinson, Peter T Campbell, Aung Ko Win, Jane C Figueiredo, Noralane M Lindor, Polly A Newcomb
BACKGROUND: Although previous studies have noted an increased risk of colorectal cancer (CRC) among moderate to heavy alcohol consumers in comparison with nondrinkers, the relation between alcohol consumption and CRC survival remains unclear. METHODS: Cases of incident invasive CRC diagnosed between 1997 and 2007 were identified via population-based cancer registries at 4 study sites in the Colon Cancer Family Registry. Study participants completed a risk-factor questionnaire on prediagnostic behaviors, including wine, beer, and liquor consumption, at the baseline...
May 15, 2017: Cancer
https://www.readbyqxmd.com/read/27842560/a-non-invasive-home-based-biomechanical-therapy-for-patients-with-spontaneous-osteonecrosis-of-the-knee
#14
Ehud Atoun, Amit Mor, Ganit Segal, Ronen Debi, Dan Grinberg, Yeshaiau Benedict, Nimrod Rozen, Yiftah Beer, Avi Elbaz
BACKGROUND: The purpose of the current study was to examine the effect of a non-invasive, home-based biomechanical treatment program for patients with spontaneous osteonecrosis of the knee (SONK). METHODS: Seventeen patients with SONK, confirmed by MRI, participated in this retrospective analysis. Patients underwent a spatiotemporal gait analysis and completed the Western Ontario and McMaster University Osteoarthritis Index (WOMAC) and the Short-Form-36 (SF-36)...
November 14, 2016: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/27724954/single-source-chest-abdomen-pelvis-cancer-staging-on-a-third-generation-dual-source-ct-system-comparison-of-automated-tube-potential-selection-to-second-generation-dual-source-ct
#15
COMPARATIVE STUDY
Clara Park, Tatjana Gruber-Rouh, Doris Leithner, Amelie Zierden, Mortiz H Albrecht, Julian L Wichmann, Boris Bodelle, Mohamed Elsabaie, Jan-Erik Scholtz, Moritz Kaup, Thomas J Vogl, Martin Beeres
BACKGROUND: Evaluation of latest generation automated attenuation-based tube potential selection (ATPS) impact on image quality and radiation dose in contrast-enhanced chest-abdomen-pelvis computed tomography examinations for gynaecologic cancer staging. METHODS: This IRB approved single-centre, observer-blinded retrospective study with a waiver for informed consent included a total of 100 patients with contrast-enhanced chest-abdomen-pelvis CT for gynaecologic cancer staging...
October 10, 2016: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://www.readbyqxmd.com/read/27695393/the-reliability-of-naturalistic-observations-of-social-physical-and-economic-environments-of-bars
#16
Christopher Morrison, Juliet P Lee, Paul J Gruenewald, Christina Mair
Drinking in bars contributes to numerous public health problems, including violence and motor vehicle crashes. In order to formulate effective preventive interventions it is essential to identify which specific features of bar environments are related to increased risks. Unobtrusive ethnographic observations are one approach that has been used to characterize these features; however no studies have assessed reliability in a representative sample of bars. We performed brief scouting assessments in all 165 bars in six purposively selected California cities, followed by unobtrusive observations from a subsequent representative sample of 97 bars which were located in low and high bar density areas of the cities...
2016: Addiction Research & Theory
https://www.readbyqxmd.com/read/27662274/alcohol-consumption-and-mortality-after-breast-cancer-diagnosis-the-health-and-functioning-in-women-study
#17
Natasha Din, Isabel Elaine Allen, William A Satariano, Joshua Demb, Dejana Braithwaite
OBJECTIVE: To determine the association of prediagnostic alcohol consumption with long-term mortality from breast cancer and other causes in a cohort of women with breast cancer. METHODS: We studied a Michigan-based cohort of 939 women aged 40-84 years, who provided complete information about the type, amount and intensity of prediagnostic alcohol consumption. Associations of alcohol consumption, based on weekly volume of alcohol consumption during the year prior to breast cancer diagnosis, with mortality were evaluated in Cox proportional hazards models, with adjustment for sociodemographic factors, body mass index, smoking, comorbidity, tumor characteristics, and treatment...
July 28, 2016: Breast Disease
https://www.readbyqxmd.com/read/27643787/timing-and-type-of-alcohol-consumption-and-the-metabolic-syndrome-elsa-brasil
#18
Bruna Angelo Vieira, Vivian Cristine Luft, Maria Inês Schmidt, Lloyd Ellwood Chambless, Dora Chor, Sandhi Maria Barreto, Bruce Bartholow Duncan
The prevalence of the metabolic syndrome is rising worldwide. Its association with alcohol intake, a major lifestyle factor, is unclear, particularly with respect to the influence of drinking with as opposed to outside of meals. We investigated the associations of different aspects of alcohol consumption with the metabolic syndrome and its components. In cross-sectional analyses of 14,375 active or retired civil servants (aged 35-74 years) participating in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil), we fitted logistic regression models to investigate interactions between the quantity of alcohol, the timing of its consumption with respect to meals, and the predominant beverage type in the association of alcohol consumption with the metabolic syndrome...
2016: PloS One
https://www.readbyqxmd.com/read/27639423/body-contouring-surgery-decreases-long-term-weight-regain-following-laparoscopic-adjustable-gastric-banding-a-matched-retrospective-cohort-study
#19
Itay Wiser, Eliezer Avinoah, Oren Ziv, Adam J Parnass, Roni Averbuch Sagie, Lior Heller, Tali Friedman
BACKGROUND: Laparoscopic adjustable gastric banding (LAGB) surgery is the safest yet least effective method for massive weight loss. Thirty to 50 percent of patients undergoing LAGB will regain part of their lost weight. OBJECTIVE: To evaluate the effect of body contouring plastic surgery (BCPS) following LAGB on long-term body mass index (BMI) control. SETTING: Department of Surgery A, Soroka University Medical Center, Beer-Sheva, Israel...
November 2016: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/27601486/predictors-of-physical-functioning-after-total-hip-arthroplasty-a-systematic-review
#20
L D Buirs, L W A H Van Beers, V A B Scholtes, T Pastoors, S Sprague, R W Poolman
OBJECTIVE: The objective of this systematic review of the literature was to identify the predictors of functional outcome after total hip arthroplasty (THA). METHOD: A systematic literature search in Web of Science, CINAHL, EMBASE and PubMed was conducted on 23 June 2015. The articles were selected based on their quality, relevance and measurement of the predictive factor. The level of evidence of all studies was determined using the GRADE rating scheme. RESULTS: The initial search resulted in 1092 citations...
2016: BMJ Open
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