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https://www.readbyqxmd.com/read/28737953/metabolic-factors-and-oxidative-stress-in-osteoarthritis-a-case-control-study
#1
Kaspar Tootsi, Aare Märtson, Jaak Kals, Kaido Paapstel, Mihkel Zilmer
Previous studies suggest that metabolic disturbances might be involved in the development of osteoarthritis (OA). Associations have been found between the individual components of metabolic syndrome (MetS) and OA. MetS has been associated with increased oxidative stress (OxS). The study aimed to clarify the role of MetS components in OA and to evaluate the levels of OxS in OA patients and in age-matched controls. Fifty-five patients with end-stage OA (age 63 ± 7 years) prior to hip or knee joint replacement surgery and 55 age-, gender- and body mass index matched controls (61 ± 8 years) were enrolled in the study...
July 24, 2017: Scandinavian Journal of Clinical and Laboratory Investigation
https://www.readbyqxmd.com/read/28711584/biomarkers-reflect-differences-in-osteoarthritis-phenotypes-of-the-lumbar-spine-the-johnston-county-osteoarthritis-project
#2
Adam P Goode, Amanda E Nelson, Virginia B Kraus, Jordan B Renner, Joanne M Jordan
OBJECTIVE: To determine differences in biomarker levels between radiographic phenotypes of facet joint osteoarthritis (FOA) only, spine OA only ((disc space narrowing (DSN) and vertebral osteophytes (OST)) or the combination of FOA and spine OA. DESIGN: A cross-sectional analysis of data from 555 participants in the Johnston County Osteoarthritis Project was performed. Lumbar spine levels were graded by severity (OST and DSN) and presence (FOA) of degeneration. Biomarkers included hyaluronan (HA) and type II collagen (CTX-II)...
July 12, 2017: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/28706837/intraosseous-infiltration-of-platelet-rich-plasma-for-severe-hip-osteoarthritis
#3
Nicolás Fiz, Juan Carlos Pérez, Jorge Guadilla, Ane Garate, Pello Sánchez, Sabino Padilla, Diego Delgado, Mikel Sánchez
This work describes a technique of platelet-rich plasma (PRP) infiltration for the treatment of severe hip osteoarthritis (OA). Although the results achieved with intra-articular infiltrations of PRP are promising, they may be insufficient in the long-term for severe hip OA. The technique consists of a combined intra-articular and intraosseous infiltration of PRP to reach all joint tissues, especially the subchondral bone, and hence facilitate a greater distribution of PRP. Diagnosis is based on clinical and radiographic findings, and patients with grade III OA according to the Tönnis scale, as well as patients who have not responded to conventional treatment, are considered candidates for this technique...
June 2017: Arthroscopy Techniques
https://www.readbyqxmd.com/read/28706834/screw-fixation-of-os-acetabuli-an-arthroscopic-technique
#4
Adrián Cuéllar, Xabier Albillos, Asier Cuéllar, Ricardo Cuéllar
An os acetabuli (OA) increases the contact area and surface area of the acetabulum and is important to maintain congruity of the hip joint. Thus preservation of this ossicle is important to prevent loss of contact area and ensure containment of the femoral head. We describe an all-arthroscopic approach to the fixation of OA with a compression screw. Initially, the fibrous tissue is debrided between the acetabular rim and the OA, a guidewire is placed through the OA up to the acetabular rim, and a screw is inserted over the wire...
June 2017: Arthroscopy Techniques
https://www.readbyqxmd.com/read/28688198/study-of-the-interactions-between-proximal-femur-3d-bone-shape-cartilage-health-and-biomechanics-in-patients-with-hip-osteoarthritis
#5
Valentina Pedoia, Michael A Samaan, Gaurav Inamdar, Matthew C Gallo, Richard B Souza, Sharmila Majumdar
In this study quantitative MRI and gait analysis were used to investigate the relationships between proximal femur 3D bone shape, cartilage morphology, cartilage biochemical composition, and joint biomechanics in subject with hip Osteoarthritis (OA). Eighty subjects underwent unilateral hip MR-imaging: T1ρ and T2 relaxation times were extracted through voxel based relaxometry and bone shape was assessed with 3D MRI-based statistical shape modeling. In addition, 3D gait analysis was performed in seventy-six of the studied subjects...
July 8, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/28672154/gait-adaptations-with-aging-in-healthy-participants-and-people-with-knee-joint-osteoarthritis
#6
Lynsey D Duffell, Stevan J Jordan, Justin P Cobb, Alison H McGregor
The relationship between age and gait characteristics in people with and without medial compartment osteoarthritis (OA) remains unclear. We aimed to characterize this relationship and to relate biomechanical and structural parameters in a subset of OA patients. Twenty five participants with diagnosed unilateral medial knee OA and 84 healthy participants, with no known knee pathology were recruited. 3D motion capture was used to analyse sagittal and coronal plane gait parameters while participants walked at a comfortable speed...
June 21, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28668808/defining-flare-in-osteoarthritis-of-the-hip-and-knee-a-systematic-literature-review-omeract-virtual-special-interest-group
#7
Marita Cross, Ludovic Dubouis, Matthieu Mangin, David J Hunter, Lyn March, Gillian Hawker, Francis Guillemin
OBJECTIVE: Beyond the exacerbation of pain in describing a flare in osteoarthritis (OA), patients and health professionals add other elements that deserve to be fully elucidated, such as effusion, swelling, and mobility limitation. To define and conceptualize the construct flare in OA, the objective was to identify the key variables, or symptoms, that worsen, and to clarify how these variables are described in the literature by patients and clinicians. METHODS: A systematic review of the literature was conducted in Medline and PsychINFO...
July 1, 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/28668804/validation-of-a-knowledge-transfer-tool-according-to-the-omeract-filter-does-web-based-real-time-iterative-calibration-enhance-the-evaluation-of-bone-marrow-lesions-in-hip-osteoarthritis
#8
Jacob L Jaremko, Omar Azmat, Robert G W Lambert, Paul Bird, Ida K Haugen, Lennart Jans, Ulrich Weber, Naomi Winn, Veronika Zubler, Walter P Maksymowych
OBJECTIVE: To assess reliability and feasibility of using a Web-based interface and interactive online calibration tool for magnetic resonance imaging (MRI) scoring of bone marrow lesions (BML) in osteoarthritis (OA), applied to the Hip MR Inflammation Scoring System (HIMRISS). METHODS: Seven readers new to HIMRISS (3 radiologists, 4 rheumatologists) scored coronal short-tau inversion recovery MRI from a hip OA observational study obtained pre- and 8-week post-steroid injection (n = 40 × 2 scans × 2 hips = 160 hips)...
July 1, 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/28667221/effectiveness-of-behavioural-change-techniques-in-physiotherapy-interventions-to-promote-physical-activity-adherence-in-patients-with-hip-and-knee-osteoarthritis-a-systematic-review-protocol
#9
Matthew Willett, Joan Duda, Charlotte Gautrey, Sally Fenton, Carolyn Greig, Alison Rushton
INTRODUCTION: Osteoarthritis (OA) is a common degenerative articular disease, the highest cause of individual level disability and a significant socioeconomic burden to healthcare services. Patient education and physical activity (PA) prescription are recommended components of interventions in several healthcare guidelines and are commonly provided by physiotherapists. However, these interventions lack long-term clinical effectiveness. Patient adherence to PA prescription requires patients to modify their PA behaviour and appears critical in maintaining symptomatic improvements...
June 30, 2017: BMJ Open
https://www.readbyqxmd.com/read/28665226/is-a-long-leg-a-risk-for-hip-or-knee-osteoarthritis
#10
Kaj Tallroth, Leena Ristolainen, Mikko Manninen
Background and purpose - 7% of the asymptomatic population has leg-length inequality (LLI) greater than 12 mm. It has been proposed that LLI of >5 mm can be associated with an increased risk of osteoarthritis (OA) of the knee and hip. We studied a possible association between LLI and OA of the knee and hip joint. Patients and methods - We followed 193 individuals (97 women, 96 men) for 29 years. The initial mean age of the participants was 43 (34-54) years, and they had no clinical histories or signs of leg symptoms...
June 30, 2017: Acta Orthopaedica
https://www.readbyqxmd.com/read/28664420/treatment-beliefs-underlying-intended-treatment-choices-in-knee-and-hip-osteoarthritis
#11
Ellen M H Selten, Rinie Geenen, Henk J Schers, Frank H J van den Hoogen, Roelien G van der Meulen-Dilling, Willemijn H van der Laan, Marc W Nijhof, Cornelia H M van den Ende, Johanna E Vriezekolk
PURPOSE: Patients' beliefs about treatment modalities for knee and hip osteoarthritis (OA) will underlie their treatment choices. Based on the Theory of Planned Behavior, it is hypothesized that patients' beliefs, subjective norm, and perceived behavioral control guide their treatment choices. Also, symptom severity and one's inherent tendency to approach or avoid situations are assumed to play a role. The objective of this study was to test whether these variables were associated with intended treatment choices in knee and hip OA...
June 29, 2017: International Journal of Behavioral Medicine
https://www.readbyqxmd.com/read/28656165/comparison-of-double-and-single-leg-weight-bearing-radiography-in-determining-knee-alignment
#12
Omid Yazdanpanah, Mahmood Karimi Mobarakeh, Masoud Nakhaei, Mohammad R Baneshi
BACKGROUND: Knee malalignment is an important modifiable cause of osteoarthritis (OA). Surgical therapeutic procedures depend on proper knee alignment assessment. The purpose of this study was to compare knee alignment parameters between double and single leg weight-bearing radiographs and to evaluate the reproducibility of inter- and intra-observer measurements. METHODS: One hundred eight patients (59 male and 49 female) with knee deformity visited at Kerman Knee Clinic were selected...
May 2017: Archives of Bone and Joint Surgery
https://www.readbyqxmd.com/read/28648741/the-importance-of-dose-in-land-based-supervised-exercise-for-people-with-hip-osteoarthritis-a-systematic-review-and-meta-analysis
#13
REVIEW
T Moseng, H Dagfinrud, G Smedslund, N Østerås
PURPOSE: To compare effects of land-based exercise programmes with high vs low or uncertain compliance with dose recommendations among people with hip osteoarthritis (OA). DESIGN: A systematic review with meta-analyses of supervised exercise programmes in people with symptomatic hip OA was conducted. Dose of the exercise interventions was evaluated according to the American College of Sports Medicine's (ACSM) recommendations for developing and maintaining cardiorespiratory fitness, muscular strength and flexibility in healthy adults...
June 23, 2017: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/28647467/reliability-and-measurement-error-of-the-osteoarthritis-research-society-international-oarsi-recommended-performance-based-tests-of-physical-function-in-people-with-hip-and-knee-osteoarthritis
#14
F Dobson, R S Hinman, M Hall, C J Marshall, T Sayer, C Anderson, N Newcomb, P W Stratford, K L Bennell
OBJECTIVE: To estimate the reliability and measurement error of performance-based tests of physical function recommended by the Osteoarthritis Research Society International (OARSI) in people with hip and/or knee osteoarthritis (OA). DESIGN: Prospective repeated measures between independent raters within a session and within-rater over a week interval. Relative reliability was estimated for 51 people with hip and/or knee OA (mean age 64.5 years, standard deviation (SD) 6...
June 22, 2017: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/28642544/resistin-promotes-the-abnormal-type-i-collagen-phenotype-of-subchondral-bone-in-obese-patients-with-end-stage-hip-osteoarthritis
#15
Ashleigh M Philp, Rebecca L Collier, Liam M Grover, Edward T Davis, Simon W Jones
The purpose of this study was to determine the effect of adiposity on the architecture and composition of hip OA subchondral bone, and to examine the pathological role of adipokines. Femoral heads were collected from normal-weight or over-weight/obese patients with hip OA. Structural parameters of subchondral bone were determined by MicroCT and type I collagen α1/α2 ratio was determined by SDS PAGE and by qRT-PCR in ex-vivo bone explants. The serum concentration of adipokines was determined by Luminex. The effect of resistin on primary OA osteoblasts was determined by analysis of Wnt pathway signal transduction, bone nodule formation, and osteoblast metabolic activity...
June 22, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28640896/beneficial-effects-of-a-gait-used-while-wearing-a-kimono-to-decrease-the-knee-adduction-moment-in-healthy-adults
#16
Susumu Ota, Yukari Ogawa, Hiroki Ota, Tomoya Fujiwara, Tadashi Sugiyama, Akira Ochi
The knee adduction moment (KAM) relates to medial knee osteoarthritis (OA). Several gait modifications to reduce the KAM for the prevention of knee OA have been studied. Most of the modifications, however, involve voluntary changes in leg alignment. Here we investigated the biomechanical effects for reducing the KAM of a walking style with a small trunk rotation and arm swing gait, which is a natural walking style used while wearing a kimono (Nanba walk) that shifts the ground reaction force toward the stance leg (reduced lever arm)...
2017: PloS One
https://www.readbyqxmd.com/read/28629944/what-are-the-risk-factors-for-dislocation-in-primary-total-hip-arthroplasty-a-multicenter-case-control-study-of-128-unstable-and-438-stable-hips
#17
M H Fessy, S Putman, A Viste, R Isida, N Ramdane, A Ferreira, A Leglise, B Rubens-Duval, N Bonin, F Bonnomet, A Combes, S Boisgard, D Mainard, S Leclercq, H Migaud
INTRODUCTION: Dislocation after total hip arthroplasty (THA) is a leading reason for surgical revision. The risk factors for dislocation are controversial, particularly those related to the patient and to the surgical procedure itself. The differences in opinion on the impact of these factors stem from the fact they are often evaluated using retrospective studies or in limited patient populations. This led us to carry out a prospective case-control study on a large population to determine: 1) the risk factors for dislocation after THA, 2) the features of these dislocations, and 3) the contribution of patient-related factors and surgery-related factors...
June 16, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/28629805/association-of-hip-radiograph-findings-with-pain-and-function-in-patients-presenting-with-low-back-pain
#18
Heidi Prather, Abby Cheng, Karen Steger May, Vaibhav Maheshwari, Linda VanDillen
BACKGROUND: Relationships between low back pain (LBP) and the hip in patient cohorts have been described primarily in patients with moderate to severe hip osteoarthritis (OA). Less is known about the links of LBP with hip radiographic findings of hip deformity and minimal OA. OBJECTIVE: The objectives were as follows: to describe the incidence of radiographic hip deformity or hip OA; to describe and compare spine- and hip-related pain and function in the subset of patients who were found to have radiographic hip deformity or hip OA; and to compare patients with evidence of radiographic hip deformity or hip OA to patients without hip radiographic findings...
June 16, 2017: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/28615667/il-6-secretion-in-osteoarthritis-patients-is-mediated-by-chondrocyte-synovial-fibroblast-cross-talk-and-is-enhanced-by-obesity
#19
Mark J Pearson, Dietmar Herndler-Brandstetter, Mohammad A Tariq, Thomas A Nicholson, Ashleigh M Philp, Hannah L Smith, Edward T Davis, Simon W Jones, Janet M Lord
Increasing evidence suggests that inflammation plays a central role in driving joint pathology in certain patients with osteoarthritis (OA). Since many patients with OA are obese and increased adiposity is associated with chronic inflammation, we investigated whether obese patients with hip OA exhibited differential pro-inflammatory cytokine signalling and peripheral and local lymphocyte populations, compared to normal weight hip OA patients. No differences in either peripheral blood or local lymphocyte populations were found between obese and normal-weight hip OA patients...
June 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28609644/outcomes-of-hip-arthroscopic-surgery-in-patients-with-t%C3%A3-nnis-grade-1-osteoarthritis-at-a-minimum-5-year-follow-up-a-matched-pair-comparison-with-a-t%C3%A3-nnis-grade-0-control-group
#20
Benjamin G Domb, Edwin O Chaharbakhshi, Danil Rybalko, Mary R Close, Jody Litrenta, Itay Perets
BACKGROUND: Studies on midterm outcomes of the arthroscopic treatment of femoroacetabular impingement (FAI) and labral tears with mild osteoarthritis (OA) are limited. PURPOSE: To evaluate outcomes of the arthroscopic treatment of FAI and labral tears in patients with mild preoperative OA (Tönnis grade 1) at a minimum 5-year follow-up, and to perform a matched-pair comparison to a control group with Tönnis grade 0. STUDY DESIGN: Cohort study; Level of evidence, 3...
June 1, 2017: American Journal of Sports Medicine
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