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https://www.readbyqxmd.com/read/29326061/neuropathic-pain-in-end-stage-hip-and-knee-osteoarthritis-differential-associations-with-patient-reported-pain-at-rest-and-pain-on-activity
#1
J D Power, A V Perruccio, R Gandhi, C Veillette, J R Davey, K Syed, N N Mahomed, Y R Rampersaud
OBJECTIVE: We investigated whether pain at rest and pain on activity were differentially associated with neuropathic pain scores in individuals with end-stage hip and knee OA. DESIGN: Study participants were 843 patients with hip or knee OA scheduled for total joint arthroplasty. In pre-surgery questionnaires, measures of socio-demographics, health status, medication use, neuropathic pain (painDETECT), pain at rest and pain on activity (WOMAC pain items), depression (HADS) and pain catastrophizing (PCS) were collected...
January 8, 2018: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/29324297/longitudinal-joint-loading-in-patients-before-and-up-to-one-year-after-unilateral-total-hip-arthroplasty
#2
Mariska Wesseling, Christophe Meyer, Kristoff Corten, Kaat Desloovere, Ilse Jonkers
Abnormal kinematics and kinetics have been reported in hip osteoarthritis (OA) patients before and after total hip arthroplasty (THA). These changes can affect the loading of the ipsilateral hip, as well as the contralateral hip and knee joint. As it is not clear how hip and knee loading evolves in THA patients during the first year after surgery, the goal of this study is to define how joint loading changes in patients before and at three evaluation times after THA surgery. Musculoskeletal modelling in combination with gait analysis data was used to calculate hip and knee contact forces in 14 patients before and 3-, 6- and 12-months after unilateral THA, as well as in 18 healthy controls...
January 5, 2018: Gait & Posture
https://www.readbyqxmd.com/read/29322706/osteoporosis-in-postmenopausal-females-with-primary-knee-osteoarthritis-in-a-vitamin-d-deficient-population
#3
Pooja Dhaon, Siddharth Kumar Das, Ragini Srivastava, Akash Asthana, Girdhar Agarwal
Aim and Objective: To find prevalence of osteoporosis (OP) in postmenopausal females with primary knee osteoarthritis (OA) in India, where there is widespread Vitamin D deficiency (VDD). Material and Methods: 75 postmenopausal women (PMW) fulfilling ACR criteria for Knee OA between 40 - 60 years of age, having OA grade 2 or more as per Kellgren Lawrence grade on anterior- posterior radiograph of the right knee were enrolled. 34 PMW of the same age with normal right knee radiograph were taken as controls...
November 2017: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/29310478/genetic-variation-of-smad3-is-associated-with-hip-osteoarthritis-in-a-chinese-han-population
#4
Fuhua Zhong, Jianwei Lu, Yangxin Wang, Hongpu Song
Objective This study was performed to investigate the association between genetic variation in SMAD3 and hip osteoarthritis (OA) in a Chinese Han population. Methods The frequency of two single nucleotide polymorphisms of SMAD3, rs1470002 and rs12901499, was examined in 500 patients with hip OA and 1080 healthy controls in a Chinese Han population. Further analysis was performed according to sex and age. Results We detected statistically significant differences in the allele frequency and genotype between the hip OA and healthy control groups...
January 1, 2018: Journal of International Medical Research
https://www.readbyqxmd.com/read/29297730/leg-loading-during-quiet-standing-and-sit-to-stand-movement-for-one-year-after-total-hip-arthroplasty
#5
Namika Miura, Keiichi Tagomori, Hisashi Ikutomo, Norikazu Nakagawa, Kensaku Masuhara
BACKGROUND: The objective of the present study was to investigate loading of the operated leg during quiet standing and sit-to-stand (STS) movement for 1 year after total hip arthroplasty (THA). METHODS: One hundred and fifty-eight patients with end-stage hip osteoarthritis (OA) who had undergone unilateral primary THA participated in this study. The load distribution on the operated and non-operated legs was computed by measuring the vertical reaction force of the operated and non-operated legs during quiet standing and STS movement...
January 3, 2018: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/29289942/patterns-of-routine-primary-care-for-osteoarthritis-in-the-uk-a-cross-sectional-electronic-health-records-study
#6
Holly Jackson, Lauren A Barnett, Kelvin P Jordan, Krysia S Dziedzic, Elizabeth Cottrell, Andrew G Finney, Zoe Paskins, John J Edwards
OBJECTIVE: To determine common patterns of recorded primary care for osteoarthritis (OA), and patient and provider characteristics associated with the quality of recorded care. DESIGN: An observational study nested within a cluster-randomised controlled trial. SETTING: Eight UK general practices who were part of the Management of Osteoarthritis in Consultations study. PARTICIPANTS: Patients recorded as consulting within the eight general practices for clinical OA...
December 29, 2017: BMJ Open
https://www.readbyqxmd.com/read/29287118/serum-n-propeptide-of-collagen-iia-piianp-as-a-marker-of-radiographic-osteoarthritis-burden
#7
Hikmat N Daghestani, Joanne M Jordan, Jordan B Renner, Michael Doherty, A Gerry Wilson, Virginia B Kraus
OBJECTIVE: Cartilage homeostasis relies on a balance of catabolism and anabolism of cartilage matrix. Our goal was to evaluate the burden of radiographic osteoarthritis and serum levels of type IIA procollagen amino terminal propeptide (sPIIANP), a biomarker representing type II collagen synthesis, in osteoarthritis. METHODS: OA burden was quantified on the basis of radiographic features as total joint faces with an osteophyte, joint space narrowing, or in the spine, disc space narrowing...
2017: PloS One
https://www.readbyqxmd.com/read/29284048/the-mediating-effect-of-body-mass-index-on-the-relationship-between-smoking-and-hip-or-knee-replacement-due-to-primary-osteoarthritis-a-population-based-cohort-study-the-hunt-study
#8
Marianne Bakke Johnsen, Alf Inge Hellevik, Milada Cvancarova Småstuen, Arnulf Langhammer, Ove Furnes, Gunnar Birkeland Flugsrud, Lars Nordsletten, John Anker Zwart, Kjersti Storheim
To investigate the total effect of smoking on total hip or knee replacement (THR/TKR) due to primary osteoarthritis (OA) and to quantify the indirect effect of smoking through body mass index (BMI). Participants from the Nord-Trøndelag Health Study (the HUNT Study) were linked to the Norwegian Arthroplasty Register to detect the first THR or TKR due to primary OA. A mediation analysis was used to decompose the total effect of smoking into a direct and indirect effect. BMI was considered a mediator in the analysis...
2017: PloS One
https://www.readbyqxmd.com/read/29283898/compliance-with-the-aaos-guidelines-for-treatment-of-osteoarthritis-of-the-knee-a-survey-of-the-american-association-of-hip-and-knee-surgeons
#9
Victor Rex Carlson, Alvin Chua Ong, Fabio Ramiro Orozco, Victor Hugo Hernandez, Rex William Lutz, Zachary Douglas Post
INTRODUCTION: The American Academy of Orthopaedic Surgeons (AAOS) published a series of evidence-based guidelines for treatment of knee osteoarthritis (OA). We studied compliance with these guidelines among orthopaedic surgeons. METHODS: We sent a survey to members of the American Association of Hip and Knee Surgeons. It included five clinical vignettes based on the Kellgren-Lawrence radiographic system for classification of knee OA. Respondents selected treatment currently supported or not supported by the AAOS guidelines...
December 22, 2017: Journal of the American Academy of Orthopaedic Surgeons
https://www.readbyqxmd.com/read/29282267/stepped-care-approach-for-medial-tibiofemoral-osteoarthritis-streamline-protocol-for-a-randomised-controlled-trial
#10
Sarah Rubia Robbins, Luciano Ricardo S Melo, Hema Urban, Leticia A Deveza, Rebecca Asher, Victoria L Johnson, David J Hunter
INTRODUCTION: Current guidelines recommend tailored interventions to optimise knee osteoarthritis (OA) management. However, models of care still have a 'one size fits all' approach, which is suboptimal as it ignores patient heterogeneity. This study aims to compare a stepped care strategy with standard care for overweight and obese persons with medial tibiofemoral OA. METHODS AND ANALYSIS: Participants will be randomised into two groups (85 each). The intervention will receive a diet and exercise programme for 18 weeks in the first step of the study...
December 26, 2017: BMJ Open
https://www.readbyqxmd.com/read/29282257/barriers-and-facilitators-of-physical-activity-in-knee-and-hip-osteoarthritis-a-systematic-review-of-qualitative-evidence
#11
Archontissa M Kanavaki, Alison Rushton, Nikolaos Efstathiou, Asma Alrushud, Rainer Klocke, Abhishek Abhishek, Joan L Duda
Physical activity (PA), including engagement in structured exercise, has a key role in the management of hip and knee osteoarthritis (OA). However, maintaining a physically active lifestyle is a challenge for people with OA. PA determinants in this population need to be understood better so that they can be optimised by public health or healthcare interventions and social policy changes. OBJECTIVES: The primary aim of this study is to conduct a systematic review of the existing qualitative evidence on barriers and facilitators of PA for patients with hip or knee OA...
December 26, 2017: BMJ Open
https://www.readbyqxmd.com/read/29280646/-anthropometric-characteristics-and-functional-fitness-of-chilean-community-dwelling-older-adults
#12
Francisco A Guede Rojas, Luis Javier Chirosa, Sergio Fuentealba, César A Vergara, David L Ulloa, Sergio E Salazar, Héctor A Márquez, Paola A Barboza
INTRODUCTION: Anthropometry and functional fitness (FF) are fundamental aspects for functional independence conservation of older adults (OA). However, little has been investigated in chilean OA. OBJECTIVE: To analyze anthropometric and FF characteristics of non-disabled OA. METHODS: One hundred and sixteen subjects participated in the study. It was determined the prevalence of weight categories (Body Mass Index [BMI]) and cardiometabolic risk (CMR) (Waist Circumference [WC], Waist-Hip Ratio [WHR] and Waist-to-Height ratio [WHtR])...
November 14, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/29275348/subgrouping-and-targeted-exercise-programmes-for-knee-and-hip-osteoarthritis-steer-oa-a-systematic-review-update-and-individual-participant-data-meta-analysis-protocol
#13
Melanie A Holden, Danielle L Burke, Jos Runhaar, Danielle van Der Windt, Richard D Riley, Krysia Dziedzic, Amardeep Legha, Amy L Evans, J Haxby Abbott, Kristin Baker, Jenny Brown, Kim L Bennell, Daniël Bossen, Lucie Brosseau, Kanda Chaipinyo, Robin Christensen, Tom Cochrane, Mariette de Rooij, Michael Doherty, Helen P French, Sheila Hickson, Rana S Hinman, Marijke Hopman-Rock, Michael V Hurley, Carol Ingram, Jesper Knoop, Inga Krauss, Chris McCarthy, Stephen P Messier, Donald L Patrick, Nilay Sahin, Laura A Talbot, Robert Taylor, Carolien H Teirlinck, Marienke van Middelkoop, Christine Walker, Nadine E Foster
INTRODUCTION: Knee and hip osteoarthritis (OA) is a leading cause of disability worldwide. Therapeutic exercise is a recommended core treatment for people with knee and hip OA, however, the observed effect sizes for reducing pain and improving physical function are small to moderate. This may be due to insufficient targeting of exercise to subgroups of people who are most likely to respond and/or suboptimal content of exercise programmes. This study aims to identify: (1) subgroups of people with knee and hip OA that do/do not respond to therapeutic exercise and to different types of exercise and (2) mediators of the effect of therapeutic exercise for reducing pain and improving physical function...
December 22, 2017: BMJ Open
https://www.readbyqxmd.com/read/29258762/the-joint-clinic-managing-excess-demand-for-hip-and-knee-osteoarthritis-referrals-using-a-new-physiotherapy-led-outpatient%C3%A2-service
#14
David P Gwynne-Jones, Liam R Hutton, Kirsten M Stout, J Haxby Abbott
BACKGROUND: There are increasing problems with access to both outpatient assessment and joint replacement surgery for patients with hip or knee osteoarthritis. METHODS: Data were collected on all patients seen at the Joint Clinic over a 2-year period with minimum 12-month follow-up. Patients were assessed by a nurse and a physiotherapist, baseline scores and demographic details collected, and an individualized personal care plan developed. Patients could be referred for a first specialist assessment (FSA) if their severity justified surgical assessment...
December 1, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29258393/postoperative-changes-in-the-systemic-inflammatory-milieu-in-older-surgical-patients
#15
Lauren Shih, Nil Guler, Daneyal Syed, William Hopkins, Kyra N McComas, Amanda Walborn, Debra Hoppensteadt, Jawed Fareed, Matthew T Rondina
Dysregulated inflammation is a central component of wound healing following surgery. We prospectively enrolled older patients (n = 25, age 65 ± 7 years) undergoing elective total knee arthroplasty or total hip arthroplasty secondary to advanced osteoarthritis (OA) and healthy controls (n = 48). Inflammatory, proangiogenic (vascular endothelial growth factor [VEGF], monocyte chemoattractant protein-1 [MCP-1], and interleukin-8 [IL-8]), and antiangiogenic (interferon γ [IFN-γ] and IL-4) factors were measured using a high-sensitivity biochip...
January 1, 2017: Clinical and Applied Thrombosis/hemostasis
https://www.readbyqxmd.com/read/29251373/altered-erector-spinae-activity-and-trunk-motion-occurs-with-moderate-and-severe-unilateral-hip-oa
#16
Janice Moreside, Ivan Wong, Derek Rutherford
People with hip osteoarthritis (OA) demonstrate altered movement patterns in the hip joint, as well as the pelvis and spine. While kinematic changes have been described in the literature, little is known about the associated erector spinae (ES) activity. Increased or prolonged ES activity may contribute to the low back pain often associated with hip OA. Using a cross-sectional cohort study, 3D trunk motions and ES surface electromyography were recorded on 19 individuals with severe OA (SOA), 20 with moderate hip OA (MOA) and 19 asymptomatic (ASYM) individuals during treadmill walking, using standardized collection and processing procedures...
December 18, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/29246141/multisite-peripheral-joint-pain-a-cross-sectional-study-of-prevalence-and-impact-on-general-health-quality-of-life-pain-intensity-and-consultation-behaviour
#17
Andrew Finney, Krysia S Dziedzic, Martyn Lewis, Emma Healey
BACKGROUND: Research into musculoskeletal conditions often focusses on pain at single sites, such as the knee, yet several studies have previously reported the high prevalence of multiple sites of musculoskeletal pain. The most common form of musculoskeletal condition is arthritis, with osteoarthritis (OA) the most common cause of joint pain in adults 45 years and over. However, there is limited recognition of the prevalence of multisite peripheral joint pain in those either living with or at risk of OA, therefore this study set out to estimate the prevalence of multisite peripheral joint pain in adults 45 years and older, and its impact on several dimensions of health...
December 16, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29245188/the-unmet-needs-of-aboriginal-australians-with-musculoskeletal-pain-a-mixed-method-systematic-review
#18
Ivan B Lin, Samantha Bunzli, Donna B Mak, Charmaine Green, Roger Goucke, Juli Coffin, Peter B O'Sullivan
OBJECTIVE: Musculoskeletal pain (MSP) conditions are the biggest cause of disability and internationally, Indigenous peoples experience a higher burden. There are conflicting reports about Aboriginal Australians and MSP. We conducted a systematic review to describe the prevalence, associated factors, impacts, care access, health care experiences, and factors associated with MSP among Aboriginal Australians. METHODS: A systematic search of quantitative and qualitative scientific and grey literature (PROSPERO number: CRD42016038342)...
December 15, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/29239664/efficacy-and-safety-of-twice-daily-sustained-release-paracetamol-formulation-for-osteoarthritis-pain-of-the-knee-or-hip-a-randomized-double-blind-placebo-controlled-twelve-week-study
#19
Kenneth Reed, Agron Collaku, Sebastian Moreira
OBJECTIVE: Evaluate efficacy and safety of an investigational, twice-daily sustained-release (SR) paracetamol formulation in subjects with knee or hip osteoarthritis (OA). METHODS: In this multicenter, double-blind, parallel study (NCT02311881), subjects with hip or knee OA were randomly assigned to SR paracetamol 2x1000 mg BID, extended-release (ER) paracetamol 2x665 mg TID, or placebo for 12 weeks. Primary endpoint was mean change from baseline through 12 weeks in WOMAC Osteoarthritis Index pain...
December 14, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/29234466/the-effect-of-variation-in-interpretation-of-the-la-trobe-radiographic-foot-atlas-on-the-prevalence-of-foot-osteoarthritis-in-older-women-the-chingford-general-population-cohort
#20
Peter McQueen, Lucy Gates, Michelle Marshall, Michael Doherty, Nigel Arden, Catherine Bowen
Background: The prevalence of foot osteoarthritis (OA) is much less understood than hip, knee and hand OA. The foot is anatomically complex and different researchers have investigated different joints with lack of methodological standardisation across studies. The La Trobe Foot Atlas (LFA) is the first to address these issues in providing quantitative assessment of radiographic foot OA, but has not been tested externally. The aim of this study was to evaluate three different interpretive approaches to using the LFA for grading OA when scoring is difficult due to indistinct views of interosseous space and joint contour...
2017: Journal of Foot and Ankle Research
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