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https://www.readbyqxmd.com/read/28732614/incidence-and-management-of-intraoperative-complications-during-small-incision-lenticule-extraction-in-3004-cases
#1
Yan Wang, Jiaonan Ma, Jiamei Zhang, Rui Dou, Hui Zhang, Liuyang Li, Wei Zhao, Pinghui Wei
PURPOSE: To assess the intraoperative complications during small-incision lenticule extraction (SMILE) for myopia and myopic astigmatism correction and evaluate visual outcomes 6 months postoperatively. SETTING: Tianjin Eye Hospital, Tianjin, China. DESIGN: Retrospective case series. METHODS: Patients who had small-incision lenticule extraction surgery were examined 1 day, 7 days, 1 month, 3 months, and 6 months postoperatively...
June 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/28728603/the-effect-of-using-social-pressure-in-cover-letters-to-improve-retention-in-a-longitudinal-health-study-an-embedded-randomised-controlled-retention-trial
#2
Sarah Cotterill, Kelly Howells, Sarah Rhodes, Peter Bower
BACKGROUND: Retention of participants in cohort studies is important for validity. One way to promote retention is by sending a persuasive cover letter with surveys. The study aimed to compare the effectiveness of a covering letter containing social pressure with a standard covering letter on retention in a health cohort study. Social pressure involves persuading people to behave in a certain way by the promise that their actions will be made know to others. We implemented a mild form of social pressure, where the recipient was told that information about whether they responded to the current survey would be noted by the research team and printed on future correspondence from the research team to the recipient...
July 20, 2017: Trials
https://www.readbyqxmd.com/read/28721471/evaluations-of-interventions-using-mathematical-models-with-exponential-and-non-exponential-distributions-for-disease-stages-the-case-of-ebola
#3
Xiaojing Wang, Yangyang Shi, Zhilan Feng, Jingan Cui
Many mathematical models for the disease transmission dynamics of Ebola have been developed and studied, particularly during and after the 2014 outbreak in West Africa. Most of these models are systems of ordinary differential equations (ODEs). One of the common assumptions made in these ODE models is that the duration of disease stages, such as latent and infectious periods, follows an exponential distribution. Gamma distributions have also been used in some of these models. It has been demonstrated that, when the models are used to evaluate disease control strategies such as quarantine or isolation, the models with exponential and Gamma distribution assumptions may generate contradictory results (Feng et al...
July 18, 2017: Bulletin of Mathematical Biology
https://www.readbyqxmd.com/read/28713833/association-between-hemoglobin-levels-and-diabetic-peripheral-neuropathy-in-patients-with-type-2-diabetes-a-cross-sectional-study-using-electronic-health-records
#4
Jun Yang, Pi-Jun Yan, Qin Wan, Hua Li
OBJECTIVE: To investigate the relationship between hemoglobin levels and diabetic peripheral neuropathy (DPN) in type 2 diabetes mellitus (T2DM). METHODS: 1511 patients with T2DM were included in the study. DPN was diagnosed based on symptoms, signs, and laboratory tests. Hemoglobin was defined as both a continuous variable and a quartile category variable. We compared patient characteristics between the no diabetic peripheral neuropathy (NDPN) and DPN groups. Logistic regression was conducted to investigate the association of DPN with hemoglobin in all T2DM patients...
2017: Journal of Diabetes Research
https://www.readbyqxmd.com/read/28709456/analyses-of-distribution-and-dosimetry-of-brain-metastases-in-small-cell-lung-cancer-with-relation-to-the-neural-stem-cell-regions-feasibility-of-sparing-the-hippocampus-in-prophylactic-cranial-irradiation
#5
Lei Zhao, Yan Shen, Jin-Dong Guo, Heng-Le Gu, Wen Yu, Jia-Ming Wang, Chang-Xing Lv, Jun Liu, Xu-Wei Cai, Xiao-Long Fu
BACKGROUND: This work aims to assess the feasibility of selectively sparing the hippocampus during prophylactic cranial irradiation (PCI) for small cell lung cancer (SCLC). METHODS: SCLC patients with brain metastases (BMs) diagnosed with MRI were enrolled. Lesions localized to the neural stem cell (NSC) compartments [subventricular zone (SVZ) or hippocampus] were analyzed. Patients were categorized by the total number of intracranial metastases, the therapy processes and the symptoms...
July 15, 2017: Radiation Oncology
https://www.readbyqxmd.com/read/28704492/cerebrospinal-fluid-matrix-metalloproteinase-9-levels-blood-brain-barrier-permeability-and-treatment-outcome-in-tuberculous-meningitis
#6
Sharada Mailankody, Gurukiran V Dangeti, Rajendiran Soundravally, Noyal M Joseph, Jharna Mandal, Tarun K Dutta, Tamilarasu Kadhiravan
OBJECTIVES: Tuberculous meningitis is characterized by elevated levels of matrix metalloproteinase 9 (MMP9) in the cerebrospinal fluid (CSF). However, it is unclear whether elevated MMP9 levels are associated with poor treatment outcome. We tested the hypothesis that pretreatment MMP9 levels in the CSF would be higher in tuberculous meningitis patients experiencing a poor treatment outcome. METHODS: We prospectively assessed the treatment outcome in a consecutive sample of human immunodeficiency virus-negative patients with tuberculous meningitis...
2017: PloS One
https://www.readbyqxmd.com/read/28697014/valproic-acid-decreases-brain-lesion-size-and-improves-neurologic-recovery-in-swine-subjected-to-traumatic-brain-injury-hemorrhagic-shock-and-polytrauma
#7
Vahagn C Nikolian, Patrick E Georgoff, Manjunath P Pai, Isabel S Dehaney, Kiril Chtraklin, Hassan Eidy, Mohamed Ghandour, Yanyan Han, Ashok Srinivasan, Yongqing Li, Hasan B Alam
BACKGROUND: We have previously shown that treatment with valproic acid (VPA) decreases brain lesion size in swine models of traumatic brain injury (TBI) and controlled hemorrhage. To translate this treatment into clinical practice, validation of drug efficacy and evaluation of pharmacologic properties in clinically realistic models of injury are necessary. In this study, we evaluate neurologic outcomes and perform pharmacokinetic analysis of a single dose of VPA in swine subjected to TBI, hemorrhagic shock, and visceral hemorrhage...
July 8, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28647661/can-we-make-still-easier-simple-in-situ-decompression-of-the-ulnar-nerve-at-the-elbow
#8
Vicente Vanaclocha, Trinidad Blanco, Pedro Ortiz, Javier López-Trigo, Vicente Bordes, Pau Capilla, Leyre Vanaclocha
BACKGROUND: in situ decompression and transposition are equally effective in cubital tunnel syndrome treatment. Both are traditionally performed in the supine position. AIM: to validate our surgical to present our technique for in situ decompression in lateral decubitus position, comparing results with other techniques used in our Institutions. METHODS: Retrospective study. Period January 2009-February 2016. 188 cubital tunnel syndrome patients, 115 males, 73 females, age mean 53...
June 21, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28618376/association-between-the-hla-b-alleles-and-carbamazepine-induced-sjs-ten-a-meta-analysis
#9
REVIEW
Qianyu Wang, Shusen Sun, Meng Xie, Kun Zhao, Xingang Li, Zhigang Zhao
PURPOSE: From our current understanding, the association between the human leukocyte antigen (HLA), HLA-B*1502, and carbamazepine(CBZ)-induced Stevens-Jonson syndrome and toxic epidermal necrolysis (SJS/TEN) in the Asian population is quite clear. However the relationship between other HLA-B alleles and CBZ-induced severe cutaneous adverse drug reactions (SCADRs) remains unclear. We aimed to identify other non-HLA-B*1502 alleles in patients with CBZ-induced SCADRs through a meta-analysis...
June 3, 2017: Epilepsy Research
https://www.readbyqxmd.com/read/28610618/relatively-frequent-switching-of-transcription-start-sites-during-cerebellar-development
#10
Peter Zhang, Emmanuel Dimont, Thomas Ha, Douglas J Swanson, Winston Hide, Dan Goldowitz
BACKGROUND: Alternative transcription start site (TSS) usage plays important roles in transcriptional control of mammalian gene expression. The growing interest in alternative TSSs and their role in genome diversification spawned many single-gene studies on differential usages of tissue-specific or temporal-specific alternative TSSs. However, exploration of the switching usage of alternative TSS usage on a genomic level, especially in the central nervous system, is largely lacking. RESULTS: In this study, We have prepared a unique set of time-course data for the developing cerebellum, as part of the FANTOM5 consortium ( http://fantom...
June 13, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28561274/statistical-shape-modelling-of-hip-and-lumbar-spine-morphology-and-their-relationship-in-the-mrc-national-survey-of-health-and-development
#11
Anastasia V Pavlova, Fiona R Saunders, Stella G Muthuri, Jennifer S Gregory, Rebecca J Barr, Kathryn R Martin, Rebecca J Hardy, Rachel Cooper, Judith E Adams, Diana Kuh, Richard M Aspden
The anatomical shape of bones and joints is important for their proper function but quantifying this, and detecting pathological variations, is difficult to do. Numerical descriptions would also enable correlations between joint shapes to be explored. Statistical shape modelling (SSM) is a method of image analysis employing pattern recognition statistics to describe and quantify such shapes from images; it uses principal components analysis to generate modes of variation describing each image in terms of a set of numerical scores after removing global size variation...
May 31, 2017: Journal of Anatomy
https://www.readbyqxmd.com/read/28560046/a-review-of-delivery-room-resuscitation-in-very-low-birth-weight-infants-in-a-middle-income-country
#12
Daynia E Ballot, Faustine Agaba, Peter A Cooper, Victor A Davies, Tanusha Ramdin, Lea Chirwa, David Rakotsoane, Lethile Madzudzo
BACKGROUND: Advanced levels of delivery room resuscitation in very low birth weight infants are reported to be associated with death and complications of prematurity. In resource limited settings, the need for delivery room resuscitation is often used as a reason to limit care in these infants. METHODS: This was a review of delivery room resuscitation in very low birth weight infants born in a tertiary hospital in South Africa between 01 January 2013 and 30 June 2016...
2017: Maternal Health, Neonatology and Perinatology
https://www.readbyqxmd.com/read/28550441/dyadic-interdependence-of-psychosocial-outcomes-among-haematological-cancer-survivors-and-their-support-persons
#13
Christine Paul, Alix Hall, Christopher Oldmeadow, Marita Lynagh, Sharon Campbell, Ken Bradstock, Anna Williamson, Mariko Carey, Rob Sanson-Fisher
PURPOSE: This study aimed to explore the dyadic relationships between unmet need, depression, and anxiety in people diagnosed with haematological cancer and their support persons. METHODS: Adult survivors (18 years+) who had been diagnosed with a haematological cancer were recruited to a cross-sectional mailed survey via five state cancer registries in Australia. Participating survivors invited a support person to also complete a survey. Structural equation modelling was used to explore the relationships among survivor and support person self-reported depression, anxiety, and unmet needs...
May 26, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28460631/association-between-pulmonary-function-and-renal-function-findings-from-china-and-australia
#14
Dahai Yu, Tao Chen, Yamei Cai, Zhanzheng Zhao, David Simmons
BACKGROUND: The relationship between obstructive lung function and impaired renal function is unclear. This study investigated the dose-response relationship between obstructive lung function and impaired renal function. METHODS: Two independent cross-sectional studies with representative sampling were applied. 1454 adults from rural Victoria, Australia (1298 with normal renal function, 156 with impaired renal function) and 5824 adults from Nanjing, China (4313 with normal renal function, 1511 with impaired renal function)...
May 1, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/28436548/an-open-source-framework-for-analyzing-n-electron-dynamics-i-multideterminantal-wave-functions
#15
Vincent Pohl, Gunter Hermann, Jean Christophe Tremblay
The aim of the present contribution is to provide a framework for analyzing and visualizing the correlated many-electron dynamics of molecular systems, where an explicitly time-dependent electronic wave packet is represented as a linear combination of N-electron wave functions. The central quantity of interest is the electronic flux density, which contains all information about the transient electronic density, the associated phase, and their temporal evolution. It is computed from the associated one-electron operator by reducing the multideterminantal, many-electron wave packet using the Slater-Condon rules...
April 24, 2017: Journal of Computational Chemistry
https://www.readbyqxmd.com/read/28436032/application-of-maldi-tof-ms-for-estimating-the-postmortem-interval-in-rat-muscle-samples
#16
Chengzhi Li, Dong Ma, Kaifei Deng, Yijiu Chen, Ping Huang, Zhenyuan Wang
Estimating the postmortem interval (PMI) is very important in the forensic sciences. Although many approaches have been used for estimating the PMI, accurate PMI calculations are still difficult. In this study, four Sprague Dawley (SD) rats were sacrificed by suffocation, and muscle samples were collected by dissection at various time intervals (0, 48, 96, and 144 h) after death. All samples were probed using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOFMS) to obtain molecular images and data for principal component analysis (PCA)...
April 23, 2017: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/28408121/effectiveness-of-live-attenuated-influenza-vaccine-and-inactivated-influenza-vaccine-in-children-during-the-2014-2015-season
#17
Huong Q McLean, Herve Caspard, Marie R Griffin, Katherine A Poehling, Manjusha Gaglani, Edward A Belongia, H Keipp Talbot, Timothy R Peters, Kempapura Murthy, Christopher S Ambrose
BACKGROUND: A clinical study found that live attenuated influenza vaccine (LAIV) was superior to inactivated influenza vaccine (IIV) against drifted A(H3N2) viruses in children. During the 2014-2015 influenza season, widespread circulation of antigenically and genetically drifted A(H3N2) viruses provided an opportunity to evaluate subtype-specific vaccine effectiveness (VE) of quadrivalent LAIV (LAIV4) and IIV in children. METHODS: Children (2-17years) with febrile acute respiratory illness <5days' duration were enrolled at 4 outpatient sites in the United States during the 2014-2015 influenza season...
May 9, 2017: Vaccine
https://www.readbyqxmd.com/read/28392541/analysis-of-strain-specific-genes-in-glutamic-acid-producing-corynebacterium-glutamicum-ssp-lactofermentum-aj-1511
#18
Yousuke Nishio, Chie Koseki, Naoto Tonouchi, Kazuhiko Matsui, Shinichi Sugimoto, Yoshihiro Usuda
Strains of the bacterium, Corynebacterium glutamicum, are widely used for the industrial production of L-glutamic acid and various other substances. C. glutamicum ssp. lactofermentum AJ 1511, formerly classified as Brevibacterium lactofermentum, and the closely related C. glutamicum ATCC 13032 have been used as industrial strains for more than 50 years. We determined the whole genome sequence of C. glutamicum AJ 1511 and performed genome-wide comparative analysis with C. glutamicum ATCC 13032 to determine strain-specific genetic differences...
April 7, 2017: Journal of General and Applied Microbiology
https://www.readbyqxmd.com/read/28368940/determination-of-perioperative-blood-loss-accuracy-or-approximation
#19
A Lopez-Picado, A Albinarrate, Borja Barrachina
BACKGROUND: Various different interventions can be used to reduce surgical blood loss; however, there is no "gold standard" for accurately measuring the volume of perioperative blood loss, and this makes it difficult to assess the efficacy of these interventions. METHODS: We used data from a previous multicenter double-blind randomized clinical trial in patients undergoing total hip arthroplasty in which we compared 2 regimens for administering tranexamic acid versus placebo...
July 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28318134/long-term-clinical-outcomes-of-successful-revascularization-with-drug-eluting-stents-for-chronic-total-occlusions-a-systematic-review-and-meta-analysis
#20
REVIEW
Lei Gao, Yabin Wang, Yuqi Liu, Feng Cao, Yundai Chen
OBJECTIVES: To determine whether successful percutaneous coronary intervention (PCI) using drug-eluting stents (DESs) have beneficial effects on long-term outcomes in patients with chronic total occlusions (CTOs) compared with failed PCIs for CTOs. BACKGROUND: Several observational studies have evaluated the long-term clinical outcomes of successful PCIs using DESs for CTOs. However, the results of these studies were inconsistent and inconclusive. METHODS: We searched five online electronic databases to identify all the publications assessing the long-term outcomes of successful and failed PCIs using DESs for CTOs...
March 2017: Catheterization and Cardiovascular Interventions
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