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Jurairat Rungruangsaphakun, Suttipun Keawsompong
Copra meal is a good source of galactomannan and it s mannooligosaccharides have prebiotic properties. However, limited data are available concerning the ideal requirements for mannan hydrolysis. Thus, optimum hydrolysis conditions for the production of oligosaccharides from copra meal hydrolysate were investigated using response surface methodology. Model validation provided good agreement between experimental results and predicted responses. Maximum oligosaccharide of 14.41 ± 0.09 mg/ml (20 ml) was obtained at an enzyme concentration of 16...
March 2018: 3 Biotech
M Hentschinski, A Kusina, K Kutak, M Serino
We calculate the transverse momentum dependent gluon-to-gluon splitting function within [Formula: see text]-factorization, generalizing the framework employed in the calculation of the quark splitting functions in Hautmann et al. (Nucl Phys B 865:54-66, arXiv:1205.1759, 2012), Gituliar et al. (JHEP 01:181, arXiv:1511.08439, 2016), Hentschinski et al. (Phys Rev D 94(11):114013, arXiv:1607.01507, 2016) and demonstrate at the same time the consistency of the extended formalism with previous results. While existing versions of [Formula: see text] factorized evolution equations contain already a gluon-to-gluon splitting function i...
2018: European Physical Journal. C, Particles and Fields
Flora Tzelepis, Christine L Paul, Robert W Sanson-Fisher, H Sharon Campbell, Kenneth Bradstock, Mariko L Carey, Anna Williamson
Due to fewer cancer services in rural locations, rural survivors may have unique unmet needs compared to urban survivors. This study compared among rural and urban haematological cancer survivors the most common "high/very high" unmet supportive care needs and the unmet need scores for five domains (information, financial concerns, access and continuity of care, relationships and emotional health). Survivors' socio-demographics, rurality, cancer history and psychological factors associated with each unmet need domain were also explored...
March 10, 2018: Annals of Hematology
Javier García-Pérez, Virginia Lope, Beatriz Pérez-Gómez, Antonio José Molina, Adonina Tardón, María Angustias Díaz Santos, Eva Ardanaz, Cristina O'Callaghan-Gordo, Jone M Altzibar, Inés Gómez-Acebo, Víctor Moreno, Rosana Peiró, Rafael Marcos-Gragera, Manolis Kogevinas, Nuria Aragonés, Gonzalo López-Abente, Marina Pollán
Breast cancer is the most frequent tumor in women worldwide, although well-established risk factors account for 53%-55% of cases. Therefore, other risk factors, including environmental exposures, may explain the remaining variation. Our objective was to assess the relationship between risk of breast cancer and residential proximity to industries, according to categories of industrial groups and specific pollutants released, in the context of a population-based multicase-control study of incident cancer carried out in Spain (MCC-Spain)...
March 7, 2018: Environmental Pollution
Lei Xu, Mary Odum
Although college is a crucial time to establish healthy behaviors for cancer prevention, little is known about cancer awareness and behaviors among US college students in less economically developed, rural areas. The purpose of this study was to examine college students' cancer-preventative knowledge and health behaviors. This cross-sectional study was conducted at a large southeastern university in the USA, on a convenience sample of students attending a campus-wide health education class. Data were collected during April and May 2017...
March 5, 2018: Journal of Cancer Education: the Official Journal of the American Association for Cancer Education
Yaning Sun, Huijuan Wang, Yuchao Tang, Haitao Zhao, Shiji Qin, Lihui Xu, Zhiyong Xia, Fengqi Zhang
Information on surgical site infection (SSI) after surgical treatment of ankle fracture is limited and remains controversial. The purpose of the present study was to determine the incidence and risk factors for SSI after open reduction and internal fixation (ORIF) of ankle fracture. Patients who underwent ORIF for ankle fracture at 3 centers between January 2015 and December 2016 were included. The potential risk factors for SSI included demographic variables, including age, sex, body mass index (BMI), hypertension, diabetes mellitus, heart disease, smoking, and excessive alcohol intake; blood test variables including preoperative white blood cell count, neutrophil count, red blood cell count, hemoglobin, total protein, albumin and globulin; injury- and surgery-related variables, including duration of operation (minutes), intraoperative blood loss, surgeon level, fracture site, accompanied dislocation, use of a drainage tube, and antibiotic use...
February 2018: Medicine (Baltimore)
Nicola Luigi Bragazzi, Alessandro Raffi, Anna Siri, Cristina Tornali, Mariano Martini
Human urine is currently the subject of biomedical investigations as a potential therapeutic resource and it continues to be used in remedies in different cultures and societies, including the Spanish culture. In this study we gather etnomedical knowledge about urotherapy and determine their associated symbolisms in Spain. A literature overview and a case study were carried out to compile urine-based remedies and as a direct analysis of symbolic systems. Urotherapy is widespread in Spanish folk medicine. Among the 204 collected remedies, those related to treatment of diseases or skin conditions predominate (63%)...
December 2017: Acta Medico-historica Adriatica: AMHA
Inês Lança de Morais, Nuno Lunet, Gabriela Albuquerque, Marcello Gelormini, Susana Casal, Albertino Damasceno, Olívia Pinho, Pedro Moreira, Jo Jewell, João Breda, Patrícia Padrão
This cross-sectional study is aimed at assessing sodium (Na) and potassium (K) content and the molar Na:K ratios of the most commonly available ready-to-eat street foods in Tajikistan and Kyrgyzstan. Four different samples of each of these foods were collected and 62 food categories were evaluated through bromatological analysis. Flame photometry was used to quantify sodium and potassium concentrations. The results show that home-made foods can be important sources of sodium. In particular, main dishes and sandwiches, respectively, contain more than 1400 and nearly 1000 mg Na in an average serving and provide approximately 70% and 50% of the maximum daily recommended values...
January 16, 2018: Nutrients
Paolo Pazzi, Anastasia Kavkovsky, Anna Shipov, Gilad Segev, Eran Dvir
Canine spirocercosis is caused by the nematode Spirocerca lupi. Migration results in oesophageal fibro-inflammatory nodules that may undergo neoplastic transformation. No studies have assessed pre- or post-surgical prognostic indicators in dogs that undergo intervention for S. lupi induced oesophageal neoplasia. This observational, multi-center study aimed to assess the outcome of dogs with Spirocerca induced sarcoma undergoing endoscopic-guided ablation (n = 12) or surgery (n = 18), and identify prognostic indicators...
January 30, 2018: Veterinary Parasitology
Wei Li, Long Li, Jun Han, Hong Wu
OBJECTIVE: The aim of this study was to conduct a meta-analysis of published reports to compare long-term outcomes after liver transplantation (LT) and liver resection (LR), respectively, in patients with HBV-related hepatocellular carcinoma (HCC) beyond the Milan criterion. METHODS: A systematic search of the Embase, Medline, PubMed databases, and the Cochrane Library was performed using both medical subject headings (MeSH) and truncated word searches to identify all comparative studies published on this topic...
January 8, 2018: Clinical Transplantation
Hongmei Zhou, Ailing Liu, Bingzhi Zhou, Cunxin Zhao, Guangjun Jin
BACKGROUND: The association between interleukin-10 (IL-10) gene rs1800896 polymorphism and susceptibility to acute pancreatitis (AP) has been investigated in several studies, but with contradictory findings. Therefore, a comprehensive meta-analysis is needed to assess the strength of such association. METHODS: Literatures on PubMed, EMBASE, and CNKI were searched to identify relevant studies. The strength of association between IL-10 gene rs1800896 polymorphism and AP risk was assessed using pooled odds ratios and 95% confidence intervals...
December 2017: Medicine (Baltimore)
Padraic J Phibbs, Ben Jones, Gregory Roe, Dale Read, Joshua Darrall-Jones, Jonathon Weakley, Andrew Rock, Kevin Till
The aims of this study were to determine the variability of weekly match and training loads in adolescent rugby union players across a competitive season, and to investigate the effect of match frequency on load distribution across different activities. Internal match and training load data (i.e. session-rating of perceived exertion (sRPE)) were collected daily from 20 players from a regional academy across a 14-week season. Data were analysed using a mixed-effects linear model, and variability was reported as a coefficient of variation (CV)...
January 5, 2018: European Journal of Sport Science
Guang Yang, Lifen Zhao, Bing Liu, Yujia Shan, Yang Li, Huimin Zhou, Li Jia
OBJECTIVES: Acquired aplastic anemia (AA) is a hematopoietic stem cell disease that leads to hematopoietic disorder and peripheral blood pancytopenia. We investigated whether nutritional support is helpful to AA recovery. METHODS: We established a rat model with AA. A nutrient mixture was administered to rats with AA through different dose gavage once per day for 55 d. Animals in this study were assigned to one of five groups: normal control (NC; group includes normal rats); AA (rats with AA); high dose (AA + nutritional mixture, 2266...
February 2018: Nutrition
Xiaomeng Yang, Shuya Li, Xingquan Zhao, Liping Liu, Yong Jiang, Zixiao Li, Yilong Wang, Yongjun Wang
BACKGROUND: Atrial fibrillation (AF) is reported to be a less frequent cause of ischemic stroke in China than in Europe and North America, but it is not clear whether this is due to underestimation. Our aim was to define the true frequency of AF-associated stroke, to determine the yield of 6-day Holter ECG to detect AF in Chinese stroke patients, and to elucidate predictors of newly detected AF. METHODS: Patients with acute ischemic stroke or transient ischemic attack (TIA) were enrolled in a prospective, multicenter cohort study of 6-day Holter monitoring within 7 days after stroke onset at 20 sites in China between 2013 and 2015...
December 4, 2017: BMC Neurology
Jing Xia, Ke-Chang Yao, Yue-Yue Liu, Guo-Jin You, Su-Yun Li, Ping Liu, Qin Zhao, Yi-Ping Wen Rui Wu, Xiao-Bo Huang, San-Jie Cao, Xin-Feng Han, Yong Huang
Fowl adenovirus (FAdV) has caused significant losses in chicken flocks throughout China in recent years. However, the current understanding of the genetic and pathogenic characteristics of the FAdV epidemic in southwestern China remains poorly understood. In this study, a total of 22 strains were isolated from liver samples of diseased chickens from farms in southwestern China. Phylogenetic analysis based on the hexon loop-1 gene showed that the 22 isolates were clustered into four distinct serotypes: FAdV serotype 4 (FAdV-4) (86...
November 29, 2017: Emerging Microbes & Infections
Ruoyu Zhang, Yiqin Wang, Kaixiong Ye, Martin Picard, Zhenglong Gu
BACKGROUND: The accumulation of mitochondrial DNA (mtDNA) mutations, and the reduction of mtDNA copy number, both disrupt mitochondrial energetics, and may contribute to aging and age-associated phenotypes. However, there are few genetic and epidemiological studies on the spectra of blood mtDNA heteroplasmies, and the distribution of mtDNA copy numbers in different age groups and their impact on age-related phenotypes. In this work, we used whole-genome sequencing data of isolated peripheral blood mononuclear cells (PBMCs) from the UK10K project to investigate in parallel mtDNA heteroplasmy and copy number in 1511 women, between 17 and 85 years old, recruited in the TwinsUK cohorts...
November 21, 2017: BMC Genomics
Flávia Sirotheau Corrêa Pontes, Márcio Ajudarte Lopes, Lucas Lacerda de Souza, Diogo Dos Santos da Mata Rezende, Alan Roger Santos-Silva, Jacks Jorge, Wagner Gomes da Silva, Fábio Ramôa Pires, André Caroli Rocha, Wladimir Gushiken de Campos, Milena Coelho Fernandes Caldato, Regina Matsunaga Martin, Felipe Paiva Fonseca, Hélder Antônio Rebelo Pontes
OBJECTIVE: To describe the oral and maxillofacial manifestations of patients diagnosed with chronic kidney disease-mineral and bone disorders. STUDY DESIGN: Over a 13-year period, clinicopathologic data of patients diagnosed with CKD-MBD who had oral and maxillofacial alterations were retrieved from the files of 4 Brazilian institutions. Data included clinical, radiographic, microscopic, and biochemical findings; treatment employed; and follow-up status. RESULTS: Twenty-one cases were identified, with 13 patients diagnosed as brown tumor of hyperparathyroidism (BTH) and 8 as osteitis fibrosa/renal osteodystrophy (OF/RO) (4 of them clinically consistent with Sagliker syndrome)...
January 2018: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
Guillaume Flandin, Karl J Friston
This technical report revisits the analysis of family-wise error rates in statistical parametric mapping-using random field theory-reported in (Eklund et al. []: arXiv 1511.01863). Contrary to the understandable spin that these sorts of analyses attract, a review of their results suggests that they endorse the use of parametric assumptions-and random field theory-in the analysis of functional neuroimaging data. We briefly rehearse the advantages parametric analyses offer over nonparametric alternatives and then unpack the implications of (Eklund et al...
November 1, 2017: Human Brain Mapping
Benjamin E Cohen, Darren F Mark, William S Cassata, Martin R Lee, Tim Tomkinson, Caroline L Smith
Mars hosts the solar system's largest volcanoes. Although their size and impact crater density indicate continued activity over billions of years, their formation rates are poorly understood. Here we quantify the growth rate of a Martian volcano by40 Ar/39 Ar and cosmogenic exposure dating of six nakhlites, meteorites that were ejected from Mars by a single impact event at 10.7 ± 0.8 Ma (2σ). We find that the nakhlites sample a layered volcanic sequence with at least four discrete eruptive events spanning 93 ± 12 Ma (1416 ± 7 Ma to 1322 ± 10 Ma (2σ))...
October 3, 2017: Nature Communications
Jennifer Schwartz, Yongfei Wang, Li Qin, Lee H Schwamm, Gregg C Fonarow, Nicole Cormier, Karen Dorsey, Robert L McNamara, Lisa G Suter, Harlan M Krumholz, Susannah M Bernheim
BACKGROUND AND PURPOSE: The Centers for Medicare & Medicaid Services publicly reports a hospital-level stroke mortality measure that lacks stroke severity risk adjustment. Our objective was to describe novel measures of stroke mortality suitable for public reporting that incorporate stroke severity into risk adjustment. METHODS: We linked data from the American Heart Association/American Stroke Association Get With The Guidelines-Stroke registry with Medicare fee-for-service claims data to develop the measures...
November 2017: Stroke; a Journal of Cerebral Circulation
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