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https://www.readbyqxmd.com/read/28920722/-comparative-evaluation-of-vertigo-in-patients-after-stapedotomy-and-stapedectomy
#1
Kinga Harmat, Gergely Thurén, László Simon, Nelli Nepp, Adrienn Németh, Imre Gerlinger, Péter Bakó
INTRODUCTION AND AIM: The reason of gradually developing conductive hearing loss in otosclerotic patients is the ossification of the stapes footplate to the surrounding bony structures and the therapy of stapes fixation is mainly surgical. In stapedotomy the footplate of the stapes is fenestrated with laser and microdrill in a diameter of 0.8 mm, whereas in stapedectomy there is complete removal of the footplate followed by the reconstruction of the ossicular chain. In the early postoperative period, temporary vertigo is frequently recorded which significantly influences the recovery...
September 2017: Orvosi Hetilap
https://www.readbyqxmd.com/read/28895733/evidence-for-a-double-well-in-the-first-triplet-excited-state-of-2-thiouracil
#2
Daisuke Koyama, Matthew J Milner, Andrew J Orr-Ewing
The computationally predicted presence of two structurally distinct minima in the first triplet excited (T1) state of 2-thiouracil (2TU) is substantiated by sub-picosecond transient vibrational absorption spectroscopy (TVAS) in deuterated acetonitrile solution. Following 300-nm ultraviolet excitation to the second singlet excited state of 2TU, a transient infrared absorption band centered at 1643 cm(-1) is observed within our minimum time resolution of 0.3 ps. It is assigned either to 2TU molecules in the S1 state, or to vibrationally hot T1 state molecules...
September 12, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28864999/early-depiction-of-a-parotid-tumour-in-the-school-of-athens-1509-1511-by-raphael-1483-1520
#3
REVIEW
Hutan Ashrafian
No abstract text is available yet for this article.
September 1, 2017: Head and Neck Pathology
https://www.readbyqxmd.com/read/28837030/the-adverse-effect-of-overweight-in-assisted-reproduction-treatment-outcomes
#4
Antonella Valeria Sampo, Celina Palena, Luciano Ganzer, Virginia Maccari, Gustavo Estofán, Mariana Hernández
OBJECTIVE: To assess Body Mass Index (BMI) effects on the results obtained from ICSI cycles. METHODS: We studied 266 ICSI cycles performed between January 2014 and December 2016. The patients were grouped according to their BMI in: Normal (18.5-24.9), Overweight (25.0-29.9) and Obese (>30). We compared the following variables between the groups: number of antral follicles, ovarian stimulation length, gonadotropin dose used, maximum estradiol level, follicles developed/antral follicles, retrieved oocytes/developed follicles and mature/retrieved oocytes, normal fertilization rate, embryo achieved/normal fertilized oocytes, clinical pregnancy and implantation rates...
September 1, 2017: JBRA Assisted Reproduction
https://www.readbyqxmd.com/read/28821958/midlife-work-related-stress-is-associated-with-late-life-cognition
#5
Shireen Sindi, Ingemar Kåreholt, Alina Solomon, Babak Hooshmand, Hilkka Soininen, Miia Kivipelto
To investigate the associations between midlife work-related stress and late-life cognition in individuals without dementia from the general population. The Cardiovascular Risk Factors, Aging and Dementia (CAIDE) study population (n = 2000) was randomly selected from independent Finnish population-based surveys (baseline mean age 50 years). Participants underwent two re-examinations in late life (mean age 71 and 78 years, respectively). 1511 subjects participated in at least one re-examination (mean total follow-up 25 years)...
August 18, 2017: Journal of Neurology
https://www.readbyqxmd.com/read/28776548/correlation-between-cholinergic-innervation-autophagy-and-etiopathology-of-benign-prostatic-hyperplasia
#6
Jian-Liang Cai, Wei-Min Yao, Yan-Qun Na
BACKGROUND: Whether cholinergic innervations and/or autophagy have a role in the etiopathology of benign prostatic hyperplasia (BPH) is still unknown. This study aimed to investigate the role of cholinergic innervation and autophagy in the etiopathology of BPH. METHODS: Male, 13-week-old spontaneous hypertension rats (spontaneous BPH animal model) were divided into three groups: an experimental group (EG, n = 24), a control group (CG, n = 24), and a normal control group (NC, n = 10)...
August 20, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28766794/an-open-source-framework-for-analyzing-n-electron-dynamics-ii-hybrid-density-functional-theory-configuration-interaction-methodology
#7
Gunter Hermann, Vincent Pohl, Jean Christophe Tremblay
In this contribution, we extend our framework for analyzing and visualizing correlated many-electron dynamics to non-variational, highly scalable electronic structure method. Specifically, an explicitly time-dependent electronic wave packet is written as a linear combination of N-electron wave functions at the configuration interaction singles (CIS) level, which are obtained from a reference time-dependent density functional theory (TDDFT) calculation. The procedure is implemented in the open-source Python program detCI@ORBKIT, which extends the capabilities of our recently published post-processing toolbox (Hermann et al...
August 1, 2017: Journal of Computational Chemistry
https://www.readbyqxmd.com/read/28732614/incidence-and-management-of-intraoperative-complications-during-small-incision-lenticule-extraction-in-3004-cases
#8
Yan Wang, Jiaonan Ma, Jiamei Zhang, Rui Dou, Hui Zhang, Liuyang Li, Wei Zhao, Pinghui Wei
PURPOSE: To assess the intraoperative complications during small-incision lenticule extraction (SMILE) for myopia and myopic astigmatism correction and evaluate visual outcomes 6 months postoperatively. SETTING: Tianjin Eye Hospital, Tianjin, China. DESIGN: Retrospective case series. METHODS: Patients who had small-incision lenticule extraction surgery were examined 1 day, 7 days, 1 month, 3 months, and 6 months postoperatively...
June 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/28728603/the-effect-of-using-social-pressure-in-cover-letters-to-improve-retention-in-a-longitudinal-health-study-an-embedded-randomised-controlled-retention-trial
#9
Sarah Cotterill, Kelly Howells, Sarah Rhodes, Peter Bower
BACKGROUND: Retention of participants in cohort studies is important for validity. One way to promote retention is by sending a persuasive cover letter with surveys. The study aimed to compare the effectiveness of a covering letter containing social pressure with a standard covering letter on retention in a health cohort study. Social pressure involves persuading people to behave in a certain way by the promise that their actions will be made know to others. We implemented a mild form of social pressure, where the recipient was told that information about whether they responded to the current survey would be noted by the research team and printed on future correspondence from the research team to the recipient...
July 20, 2017: Trials
https://www.readbyqxmd.com/read/28721471/evaluations-of-interventions-using-mathematical-models-with-exponential-and-non-exponential-distributions-for-disease-stages-the-case-of-ebola
#10
Xiaojing Wang, Yangyang Shi, Zhilan Feng, Jingan Cui
Many mathematical models for the disease transmission dynamics of Ebola have been developed and studied, particularly during and after the 2014 outbreak in West Africa. Most of these models are systems of ordinary differential equations (ODEs). One of the common assumptions made in these ODE models is that the duration of disease stages, such as latent and infectious periods, follows an exponential distribution. Gamma distributions have also been used in some of these models. It has been demonstrated that, when the models are used to evaluate disease control strategies such as quarantine or isolation, the models with exponential and Gamma distribution assumptions may generate contradictory results (Feng et al...
July 18, 2017: Bulletin of Mathematical Biology
https://www.readbyqxmd.com/read/28713833/association-between-hemoglobin-levels-and-diabetic-peripheral-neuropathy-in-patients-with-type-2-diabetes-a-cross-sectional-study-using-electronic-health-records
#11
Jun Yang, Pi-Jun Yan, Qin Wan, Hua Li
OBJECTIVE: To investigate the relationship between hemoglobin levels and diabetic peripheral neuropathy (DPN) in type 2 diabetes mellitus (T2DM). METHODS: 1511 patients with T2DM were included in the study. DPN was diagnosed based on symptoms, signs, and laboratory tests. Hemoglobin was defined as both a continuous variable and a quartile category variable. We compared patient characteristics between the no diabetic peripheral neuropathy (NDPN) and DPN groups. Logistic regression was conducted to investigate the association of DPN with hemoglobin in all T2DM patients...
2017: Journal of Diabetes Research
https://www.readbyqxmd.com/read/28709456/analyses-of-distribution-and-dosimetry-of-brain-metastases-in-small-cell-lung-cancer-with-relation-to-the-neural-stem-cell-regions-feasibility-of-sparing-the-hippocampus-in-prophylactic-cranial-irradiation
#12
Lei Zhao, Yan Shen, Jin-Dong Guo, Heng-Le Gu, Wen Yu, Jia-Ming Wang, Chang-Xing Lv, Jun Liu, Xu-Wei Cai, Xiao-Long Fu
BACKGROUND: This work aims to assess the feasibility of selectively sparing the hippocampus during prophylactic cranial irradiation (PCI) for small cell lung cancer (SCLC). METHODS: SCLC patients with brain metastases (BMs) diagnosed with MRI were enrolled. Lesions localized to the neural stem cell (NSC) compartments [subventricular zone (SVZ) or hippocampus] were analyzed. Patients were categorized by the total number of intracranial metastases, the therapy processes and the symptoms...
July 15, 2017: Radiation Oncology
https://www.readbyqxmd.com/read/28704492/cerebrospinal-fluid-matrix-metalloproteinase-9-levels-blood-brain-barrier-permeability-and-treatment-outcome-in-tuberculous-meningitis
#13
Sharada Mailankody, Gurukiran V Dangeti, Rajendiran Soundravally, Noyal M Joseph, Jharna Mandal, Tarun K Dutta, Tamilarasu Kadhiravan
OBJECTIVES: Tuberculous meningitis is characterized by elevated levels of matrix metalloproteinase 9 (MMP9) in the cerebrospinal fluid (CSF). However, it is unclear whether elevated MMP9 levels are associated with poor treatment outcome. We tested the hypothesis that pretreatment MMP9 levels in the CSF would be higher in tuberculous meningitis patients experiencing a poor treatment outcome. METHODS: We prospectively assessed the treatment outcome in a consecutive sample of human immunodeficiency virus-negative patients with tuberculous meningitis...
2017: PloS One
https://www.readbyqxmd.com/read/28697014/valproic-acid-decreases-brain-lesion-size-and-improves-neurologic-recovery-in-swine-subjected-to-traumatic-brain-injury-hemorrhagic-shock-and-polytrauma
#14
Vahagn C Nikolian, Patrick E Georgoff, Manjunath P Pai, Isabel S Dehaney, Kiril Chtraklin, Hassan Eidy, Mohamed Ghandour, Yanyan Han, Ashok Srinivasan, Yongqing Li, Hasan B Alam
BACKGROUND: We have previously shown that treatment with valproic acid (VPA) decreases brain lesion size in swine models of traumatic brain injury (TBI) and controlled hemorrhage. To translate this treatment into clinical practice, validation of drug efficacy and evaluation of pharmacologic properties in clinically realistic models of injury are necessary. In this study, we evaluate neurologic outcomes and perform pharmacokinetic analysis of a single dose of VPA in swine subjected to TBI, hemorrhagic shock, and visceral hemorrhage...
July 8, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28647661/can-we-make-simple-in-situ-decompression-of-the-ulnar-nerve-at-the-elbow-still-easier
#15
Vicente Vanaclocha, Trinidad Blanco, Pedro Ortiz, Javier Lopez-Trigo, Pau Capilla, Vicente Bordes-Garcia, Leyre Vanaclocha
BACKGROUND: In situ decompression and transposition are equally effective in cubital tunnel syndrome treatment. Both are traditionally performed in the supine position. OBJECTIVE: To validate our surgical technique for in situ decompression in the lateral decubitus position, comparing results with other techniques used in our institutions. METHODS: A retrospective study was performed from January 2009 to February 2016, of 188 patients with cubital tunnel syndrome 115 males, 73 females; mean age, 53...
June 21, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28618376/association-between-the-hla-b-alleles-and-carbamazepine-induced-sjs-ten-a-meta-analysis
#16
REVIEW
Qianyu Wang, Shusen Sun, Meng Xie, Kun Zhao, Xingang Li, Zhigang Zhao
PURPOSE: From our current understanding, the association between the human leukocyte antigen (HLA), HLA-B*1502, and carbamazepine(CBZ)-induced Stevens-Jonson syndrome and toxic epidermal necrolysis (SJS/TEN) in the Asian population is quite clear. However the relationship between other HLA-B alleles and CBZ-induced severe cutaneous adverse drug reactions (SCADRs) remains unclear. We aimed to identify other non-HLA-B*1502 alleles in patients with CBZ-induced SCADRs through a meta-analysis...
June 3, 2017: Epilepsy Research
https://www.readbyqxmd.com/read/28610618/relatively-frequent-switching-of-transcription-start-sites-during-cerebellar-development
#17
Peter Zhang, Emmanuel Dimont, Thomas Ha, Douglas J Swanson, Winston Hide, Dan Goldowitz
BACKGROUND: Alternative transcription start site (TSS) usage plays important roles in transcriptional control of mammalian gene expression. The growing interest in alternative TSSs and their role in genome diversification spawned many single-gene studies on differential usages of tissue-specific or temporal-specific alternative TSSs. However, exploration of the switching usage of alternative TSS usage on a genomic level, especially in the central nervous system, is largely lacking. RESULTS: In this study, We have prepared a unique set of time-course data for the developing cerebellum, as part of the FANTOM5 consortium ( http://fantom...
June 13, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28561274/statistical-shape-modelling-of-hip-and-lumbar-spine-morphology-and-their-relationship-in-the-mrc-national-survey-of-health-and-development
#18
Anastasia V Pavlova, Fiona R Saunders, Stella G Muthuri, Jennifer S Gregory, Rebecca J Barr, Kathryn R Martin, Rebecca J Hardy, Rachel Cooper, Judith E Adams, Diana Kuh, Richard M Aspden
The anatomical shape of bones and joints is important for their proper function but quantifying this, and detecting pathological variations, is difficult to do. Numerical descriptions would also enable correlations between joint shapes to be explored. Statistical shape modelling (SSM) is a method of image analysis employing pattern recognition statistics to describe and quantify such shapes from images; it uses principal components analysis to generate modes of variation describing each image in terms of a set of numerical scores after removing global size variation...
August 2017: Journal of Anatomy
https://www.readbyqxmd.com/read/28560046/a-review-of-delivery-room-resuscitation-in-very-low-birth-weight-infants-in-a-middle-income-country
#19
Daynia E Ballot, Faustine Agaba, Peter A Cooper, Victor A Davies, Tanusha Ramdin, Lea Chirwa, David Rakotsoane, Lethile Madzudzo
BACKGROUND: Advanced levels of delivery room resuscitation in very low birth weight infants are reported to be associated with death and complications of prematurity. In resource limited settings, the need for delivery room resuscitation is often used as a reason to limit care in these infants. METHODS: This was a review of delivery room resuscitation in very low birth weight infants born in a tertiary hospital in South Africa between 01 January 2013 and 30 June 2016...
2017: Maternal Health, Neonatology and Perinatology
https://www.readbyqxmd.com/read/28550441/dyadic-interdependence-of-psychosocial-outcomes-among-haematological-cancer-survivors-and-their-support-persons
#20
Christine Paul, Alix Hall, Christopher Oldmeadow, Marita Lynagh, Sharon Campbell, Ken Bradstock, Anna Williamson, Mariko Carey, Rob Sanson-Fisher
PURPOSE: This study aimed to explore the dyadic relationships between unmet need, depression, and anxiety in people diagnosed with haematological cancer and their support persons. METHODS: Adult survivors (18 years+) who had been diagnosed with a haematological cancer were recruited to a cross-sectional mailed survey via five state cancer registries in Australia. Participating survivors invited a support person to also complete a survey. Structural equation modelling was used to explore the relationships among survivor and support person self-reported depression, anxiety, and unmet needs...
May 26, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
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