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https://www.readbyqxmd.com/read/27893870/associations-between-hydration-status-intravenous-fluid-administration-and-outcomes-of-patients-infected-with-shiga-toxin-producing-escherichia-coli-a-systematic-review-and-meta-analysis
#1
Silviu Grisaru, Jianling Xie, Susan Samuel, Lisa Hartling, Phillip I Tarr, David Schnadower, Stephen B Freedman
Importance: The associations between hydration status, intravenous fluid administration, and outcomes of patients infected with Shiga toxin-producing Escherichia coli (STEC) remain unclear. Objective: To determine the relationship between hydration status, the development and severity of hemolytic uremic syndrome (HUS), and adverse outcomes in STEC-infected individuals. Data Sources: MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials via the OvidSP platform, PubMed via the National Library of Medicine, CINAHL Plus with full text, Scopus, Web of Science, ClinicalTrials...
November 28, 2016: JAMA Pediatrics
https://www.readbyqxmd.com/read/27881044/promoting-physical-activity-in-hospitalized-patients-with-mild-ischemic-stroke-a-pilot-study
#2
Masashi Kanai, Masafumi Nozoe, Kazuhiro P Izawa, Yuka Takeuchi, Hiroki Kubo, Kyoshi Mase, Shinichi Shimada
BACKGROUND: Patients with acute stroke spend most of their hospital day inactive. However, a method to promote physical activity (PA) in stroke has not been established. OBJECTIVE: To evaluate the effectiveness of promoting PA by enhancing self-efficacy in hospitalized patients with mild ischemic stroke. DESIGN: Pre-post interventional study. METHODS: Hospitalized patients with mild ischemic stroke who could walk without assistance were recruited...
November 24, 2016: Topics in Stroke Rehabilitation
https://www.readbyqxmd.com/read/27851147/1511-acute-kidney-injury-in-trauma-patients-in-japan-a-two-year-prospective-observational-study
#3
Jun Fujinaga, Akira Kuriyama, Noriaki Shimada
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27829646/october-surprises
#4
(no author information available yet)
Ushered in with the rampage of Hurricane Matthew, later days brightened in this month that has often been harbinger of both good and bad news for Cuba and the world. Hurricane Matthew ripped through Eastern Cuba, devastating the historic town of Baracoa (Cuba's first capital, founded in 1511) and the village of Maisí, where the morning sun first rises over Cuban territory. Wind and flood leveled hundreds of homes, brought down the power grid and destroyed crops. Yet there was no loss of human life, unlike in neighboring Haiti and other countries in Matthew's path, and unlike in Cuba in 1963, when Hurricane Flora caused more than 1200 deaths...
October 2016: MEDICC Review
https://www.readbyqxmd.com/read/27784313/an-optimised-age-based-dosing-regimen-for-single-low-dose-primaquine-for-blocking-malaria-transmission-in-cambodia
#5
Rithea Leang, Naw Htee Khu, Mavuto Mukaka, Mark Debackere, Rupam Tripura, Soy Ty Kheang, Say Chy, Neeraj Kak, Philippe Buchy, Arnaud Tarantola, Didier Menard, Arantxa Roca-Felterer, Rick M Fairhurst, Sim Kheng, Sinoun Muth, Song Ngak, Arjen M Dondorp, Nicholas J White, Walter Robert John Taylor
BACKGROUND: In 2012, the World Health Organization recommended the addition of single low-dose primaquine (SLDPQ, 0.25 mg base/kg body weight) to artemisinin combination therapies to block the transmission of Plasmodium falciparum without testing for glucose-6-phosphate dehydrogenase deficiency. The targeted group was non-pregnant patients aged ≥ 1 year (later changed to ≥ 6 months) with acute uncomplicated falciparum malaria, primarily in countries with artemisinin-resistant P...
October 27, 2016: BMC Medicine
https://www.readbyqxmd.com/read/27779688/-retracted-inhibitory-effects-of-ethyl-pyruvate-administration-on-human-gastric-cancer-growth-via-regulation-of-the-hmgb1-rage-and-akt-pathways-in%C3%A2-vitro-and-in%C3%A2-vivo
#6
Jing Zhang, Jin-Shui Zhu, Zhou Zhou, Wei-Xiong Chen, Ni-Wei Chen
Following the publication of this article, an interested reader drew to the attention of the Editorial Board that the above article appeared to contain a series of Figures that featured duplicated data. Following an internal investigation, the Editorial Board reached the conclusion that the allegations of the reader were well-founded. Specifically, the GAPDH bands shown in Figs. 2 and 3 are identical with those in Figs. 4C and 5D, with the exception that the images have been reversed. Furthermore, certain data in Fig...
October 19, 2016: Oncology Reports
https://www.readbyqxmd.com/read/27774265/ventricular-conduction-abnormalities-as-predictors-of-long-term-survival-in-acute-de-novo-and-decompensated-chronic-heart-failure
#7
Heli Tolppanen, Krista Siirila-Waris, Veli-Pekka Harjola, David Marono, Jiri Parenica, Philipp Kreutzinger, Tuomo Nieminen, Marie Pavlusova, Tuukka Tarvasmaki, Raphael Twerenbold, Jukka Tolonen, Roman Miklik, Markku S Nieminen, Jindrich Spinar, Christian Mueller, Johan Lassus
AIMS: Data on the prognostic role of left and right bundle branch blocks (LBBB and RBBB), and nonspecific intraventricular conduction delay (IVCD; QRS ≥ 110 ms, no BBB) in acute heart failure (AHF) are controversial. Our aim was to investigate electrocardiographic predictors of long-term survival in patients with de novo AHF and acutely decompensated chronic heart failure (ADCHF). METHODS AND RESULTS: We analysed the admission electrocardiogram of 982 patients from a multicenter European cohort of AHF with 3...
March 2016: ESC Heart Failure
https://www.readbyqxmd.com/read/27735222/methodology-to-customize-maximal-isometric-forces-for-hill-type-muscle-models
#8
Fabien Dal Maso, Mickaël Begon, Maxime Raison
One approach to increasing the confidence of muscle force estimation via musculoskeletal models is to minimize the root mean square error (RMSE) between joint torques estimated from electromyographic-driven musculoskeletal models and those computed using inverse dynamics. We propose a method that reduces RMSE by selecting subsets of combinations of maximal voluntary isometric contraction (MVIC) trials that minimize RMSE. Twelve participants performed three elbow MVIC in flexion and in extension of both sides...
October 13, 2016: Journal of Applied Biomechanics
https://www.readbyqxmd.com/read/27727451/postoperative-radiotherapy-for-non-small-cell-lung-cancer
#9
REVIEW
Sarah Burdett, Larysa Rydzewska, Jayne Tierney, David Fisher, Mahesh Kb Parmar, Rodrigo Arriagada, Jean Pierre Pignon, Cecile Le Pechoux
BACKGROUND: The role of postoperative radiotherapy (PORT) in the treatment of patients with completely resected non-small cell lung cancer (NSCLC) was not clear. A systematic review and individual participant data meta-analysis was undertaken to evaluate available evidence from randomised controlled trials (RCTs). These results were first published in Lung Cancer in 2013. OBJECTIVES: To evaluate the effects of PORT on survival and recurrence in patients with completely resected NSCLC...
October 11, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27706103/in-vitro-metabolic-studies-of-rev-erb-agonists-sr9009-and-sr9011
#10
Lore Geldof, Koen Deventer, Kris Roels, Eva Tudela, Peter Van Eeno
SR9009 and SR9011 are attractive as performance-enhancing substances due to their REV-ERB agonist effects and thus circadian rhythm modulation activity. Although no pharmaceutical preparations are available yet, illicit use of SR9009 and SR9011 for doping purposes can be anticipated, especially since SR9009 is marketed in illicit products. Therefore, the aim was to identify potential diagnostic metabolites via in vitro metabolic studies to ensure effective (doping) control. The presence of SR9009 could be demonstrated in a black market product purchased over the Internet...
October 3, 2016: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/27699634/use-of-a-c1-inhibitor-concentrate-in-adults-%C3%A2-65-years-of-age-with-hereditary-angioedema-findings-from-the-international-berinert-%C3%A2-c1-inh-registry
#11
Anette Bygum, Inmaculada Martinez-Saguer, Murat Bas, Jeffrey Rosch, Jonathan Edelman, Mikhail Rojavin, Debora Williams-Herman
BACKGROUND: Treatment of hereditary angioedema (HAE) in 'older adults' (those aged ≥65 years) has not been well studied. The international Berinert Patient Registry collected data on the use of intravenous plasma-derived, pasteurized, nanofiltered C1-inhibitor concentrate (pnfC1-INH; Berinert(®)/CSL Behring) in patients of any age, including many older adults. METHODS: This observational registry, conducted from 2010 to 2014 at 30 US and seven European sites, gathered prospective (post-enrollment) and retrospective (pre-enrollment) usage and adverse event (AE) data on subjects treated with pnfC1-INH...
November 2016: Drugs & Aging
https://www.readbyqxmd.com/read/27696629/association-between-hiv-infection-and-socio-economic-status-evidence-from-a-semirural-area-of-southern-mozambique
#12
Clara Pons-Duran, Raquel González, Llorenç Quintó, Khatia Munguambe, Joan Tallada, Denise Naniche, Charfudin Sacoor, Elisa Sicuri
OBJECTIVES: To analyse the association between socio-economic status (SES) and HIV in Manhiça, a district of Southern Mozambique with one of the highest HIV prevalences in the world. METHODS: Data were gathered from two cross-sectional surveys performed in 2010 and 2012 among 1511 adults and from the household census of the district's population. Fractional polynomial logit models were used to analyse the association between HIV and SES, controlling for age and sex and taking into account the nonlinearity of covariates...
December 2016: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/27684386/postoperative-radiotherapy-for-non-small-cell-lung-cancer
#13
Sarah Burdett, Larysa Rydzewska, Jayne Tierney, David Fisher, Mahesh Kb Parmar, Rodrigo Arriagada, Jean Pierre Pignon, Cecile Le Pechoux
BACKGROUND: The role of postoperative radiotherapy (PORT) in the treatment of patients with completely resected non-small cell lung cancer (NSCLC) was not clear. A systematic review and individual participant data meta-analysis was undertaken to evaluate available evidence from randomised controlled trials (RCTs). These results were first published in Lung Cancer in 2013. OBJECTIVES: To evaluate the effects of PORT on survival and recurrence in patients with completely resected NSCLC...
September 29, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27678189/discovery-of-the-pulmonary-circulation-ancient-persia-and-michel-servetus-1511-1453
#14
(no author information available yet)
No abstract text is available yet for this article.
September 14, 2016: European Heart Journal
https://www.readbyqxmd.com/read/27670204/-210-po-bioaccumulation-and-trophic-transfer-in-marine-food-chains-in-the-northern-arabian-gulf
#15
S Uddin, S W Fowler, M Behbehani, M Metian
The tendency of (210)Po to concentrate in body tissue poses a serious concern of radiological safety. This study compiles available information and presents recent (210)Po data for the marine food web in the northern Gulf waters. Since (210)Po is concentrated in marine biota, a large number of samples of various marine organisms covering several trophic levels, from microalgae to sharks, were analyzed. (210)Po was found to be highly concentrated in several marine species with the highest (210)Po concentrations found in yellowfin tuna, i...
September 23, 2016: Journal of Environmental Radioactivity
https://www.readbyqxmd.com/read/27670090/quality-of-basic-maternal-care-functions-in-health-facilities-of-five-african-countries-an-analysis-of-national-health-system-surveys
#16
Margaret E Kruk, Hannah H Leslie, Stéphane Verguet, Godfrey M Mbaruku, Richard M K Adanu, Ana Langer
BACKGROUND: Global efforts to increase births at health-care facilities might not reduce maternal or newborn mortality if quality of care is insufficient. However, little systematic evidence exists for the quality at health facilities caring for women and newborn babies in low-income countries. We analysed the quality of basic maternal care functions and its association with volume of deliveries and surgical capacity in health-care facilities in five sub-Saharan African countries. METHODS: In this analysis, we combined nationally representative health system surveys (Service Provision Assessments by the Demographic and Health Survery Programme) with data for volume of deliveries and quality of delivery care from Kenya, Namibia, Rwanda, Tanzania, and Uganda...
November 2016: Lancet Global Health
https://www.readbyqxmd.com/read/27640617/-risk-of-thromboembolism-in-atrial-fibrillation
#17
Zoltán Csanádi
Atrial fibrillation is considered as one of the cardiovascular pandemics of our days due to its increasing prevalence and the significant burden on healthcare systems. Management, especially prevention of thromboembolism associated with the arrhythmia is still a challenge even with recently available treatment options. Herein, the author reviews the possibilities of risk stratification and stroke prevention, which are important to all medical professionals who potentially encounter patients with this arrhythmia...
September 2016: Orvosi Hetilap
https://www.readbyqxmd.com/read/27581934/impact-of-the-ppar-gamma-2-gene-polymorphisms-on-the-metabolic-state-of-postmenopausal-women
#18
Bogna Grygiel-Gorniak, Maria Mosor, Justyna Marcinkowska, Juliusz Przyslawski, Jerzy Nowak
The relationship Pro12Ala (rs1801282) and C1431T (rs3856806) polymorphisms of PPAR gamma-2 with glucose and lipid metabolism is not clear after menopause. We investigated the impact of the Pro12Ala and C1431T silent substitution in the 6th exon in PPAR gamma-2 gene on nutritional and metabolic status in 271 postmenopausal women (122 lean and 149 obese). The general linear model (GLM) approach to the two-way analysis of variance (ANOVA) was used to infer the interactions between the analysed genotypes. The frequency of the Pro-T haplotype was higher in obese than in lean women (p less than 0...
September 2016: Journal of Biosciences
https://www.readbyqxmd.com/read/27458241/eight-sages-over-five-centuries-share-oxygen-s-discovery
#19
John W Severinghaus
During the last century, historians have discovered that between the 13th and 18th centuries, at least six sages discovered that the air we breathe contains something that we need and use. Ibn al-Nafis (1213-1288) in Cairo and Michael Servetus (1511-1553) in France accurately described the pulmonary circulation and its effect on blood color. Michael Sendivogius (1566-1636) in Poland called a part of air "the food of life" and identified it as the gas made by heating saltpetre. John Mayow (1641-1679) in Oxford found that one-fifth of air was a special gas he called "spiritus nitro aereus...
September 2016: Advances in Physiology Education
https://www.readbyqxmd.com/read/27449654/physical-activity-practices-policies-and-environments-in-washington-state-child-care-settings-results-of-a-statewide-survey
#20
Pooja S Tandon, Kelly M Walters, Bridget M Igoe, Elizabeth C Payne, Donna B Johnson
Objectives Child care is an important setting for the promotion of physical activity (PA) in early childhood. The purpose of this study was to examine the associations between specific PA environments and recommended practices in child care settings as well as the degree to which child care settings met recommended standards for total PA time. Methods In 2013, all programs licensed to care for children ages 2-5 in WA state were surveyed about their PA related practices. Logistic regression was used to determine odds of meeting best-practice standards for outdoor time and PA...
July 22, 2016: Maternal and Child Health Journal
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