keyword
MENU ▼
Read by QxMD icon Read
search

"default network"

keyword
https://www.readbyqxmd.com/read/28167837/neural-mechanisms-of-mismatch-negativity-dysfunction-in-schizophrenia
#1
M Lee, P Sehatpour, M J Hoptman, P Lakatos, E C Dias, J T Kantrowitz, A M Martinez, D C Javitt
Schizophrenia is associated with cognitive deficits that reflect impaired cortical information processing. Mismatch negativity (MMN) indexes pre-attentive information processing dysfunction at the level of primary auditory cortex. This study investigates mechanisms underlying MMN impairments in schizophrenia using event-related potential, event-related spectral decomposition (ERSP) and resting state functional connectivity (rsfcMRI) approaches. For this study, MMN data to frequency, intensity and duration-deviants were analyzed from 69 schizophrenia patients and 38 healthy controls...
February 7, 2017: Molecular Psychiatry
https://www.readbyqxmd.com/read/28130193/spatial-distribution-of-resting-state-bold-regional-homogeneity-as-a-predictor-of-brain-glucose-uptake-a-study-in-healthy-aging
#2
Michaël Bernier, Etienne Croteau, Christian-Alexandre Castellano, Stephen C Cunnane, Kevin Whittingstall
Positron emission tomography using [18F]-fluorodeoxyglucose (PET-FDG) is the primary imaging modality used to measure glucose metabolism in the brain (CMRGlu). CMRGlu has been used as a biomarker of brain aging and neurodegenerative diseases, but the complexity and invasive nature of PET often limits its use in research. There is therefore great interest in developing non-invasive metrics for estimating brain CMRGlu. We therefore investigated resting state fMRI metrics such as regional homogeneity (ReHo), amplitude of low-frequency fluctuations (ALFF) and regional global connectivity (Closeness) with multiple analytical approaches to determine their relationship to CMRGlu...
January 24, 2017: NeuroImage
https://www.readbyqxmd.com/read/28089970/spatial-working-memory-impairment-in-patients-with-non-neuropsychiatric-systemic-lupus-erythematosus-a-blood-oxygen-level-dependent-functional-magnetic-resonance-imaging-study
#3
Chun-Min Zhu, Ye Ma, Lei Xie, Jin-Zhuang Huang, Zong-Bo Sun, Shou-Xing Duan, Zhi-Rong Lin, Jing-Jing Yin, Hong-Bo Le, Dan-Miao Sun, Wen-Can Xu, Shu-Hua Ma
OBJECTIVE: Using ethology and functional magnetic resonance imaging (fMRI) to explore mild cognitive dysfunction and spatial working memory (WM) impairment in patients with systemic lupus erythematosus (SLE) without overt neuropsychiatric symptoms (non-NPSLE) and to study whether any clinical biomarkers could serve as predictors of brain dysfunction in this disease. METHODS: Eighteen non-NPSLE patients and 18 matched subjects were all tested using the Montreal cognitive assessment scale test and scanned using blood-oxygen-level dependent fMRI while performing the n-back task to investigate the activation intensity of some cognition-related areas...
January 15, 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/28080963/is-the-cardiac-monitoring-function-related-to-the-self-in-both-the-default-network-and-right-anterior-insula
#4
Mariana Babo-Rebelo, Nicolai Wolpert, Claude Adam, Dominique Hasboun, Catherine Tallon-Baudry
The self has been proposed to be rooted in the neural monitoring of internal bodily signals and might thus involve interoceptive areas, notably the right anterior insula (rAI). However, studies on the self consistently showed the involvement of midline default network (DN) nodes, without referring to visceral monitoring. Here, we investigate this apparent discrepancy. We previously showed that neural responses to heartbeats in the DN encode two different self-dimensions, the agentive 'I' and the introspective 'Me', in a whole-brain analysis of magnetoencephalography (MEG) data...
November 19, 2016: Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
https://www.readbyqxmd.com/read/28040543/interactions-between-the-default-network-and-dorsal-attention-network-vary-across-default-subsystems-time-and-cognitive-states
#5
Matthew L Dixon, Jessica R Andrews-Hanna, R Nathan Spreng, Zachary C Irving, Caitlin Mills, Manesh Girn, Kalina Christoff
Anticorrelation between the default network (DN) and dorsal attention network (DAN) is thought to be an intrinsic aspect of functional brain organization reflecting competing functions. However, the effect size of functional connectivity (FC) between the DN and DAN has yet to be established. Furthermore, the stability of anticorrelations across distinct DN subsystems, different contexts, and time, remains unexplored. In study 1 we summarize effect sizes of DN-DAN FC from 20 studies, and in study 2 we probe the variability of DN-DAN interactions across six different cognitive states in a new data set...
February 15, 2017: NeuroImage
https://www.readbyqxmd.com/read/28002981/resting-state-fmri-data-reflects-default-network-activity-rather-than-null-data-a-defense-of-commonly-employed-methods-to-correct-for-multiple-comparisons
#6
Scott D Slotnick
Analysis of functional magnetic resonance imaging (fMRI) data typically involves over one hundred thousand independent statistical tests; therefore, it is necessary to correct for multiple comparisons to control familywise error. Eklund, Nichols, and Knutsson (2016, Proceedings of the National Academy of Sciences of the United States of America, 113, 7900-7905) used resting-state fMRI data to evaluate commonly employed methods to correct for multiple comparison and reported unacceptable rates of familywise error...
December 22, 2016: Cognitive Neuroscience
https://www.readbyqxmd.com/read/27999185/early-and-progressive-deficit-of-neuronal-activity-patterns-in-a-model-of-local-amyloid-pathology-in-mouse-prefrontal-cortex
#7
Fani Koukouli, Marie Rooy, Uwe Maskos
Alzheimer's Disease (AD) is the most common form of dementia. The condition predominantly affects the cerebral cortex and hippocampus and is characterized by the spread of amyloid plaques and neurofibrillary tangles (NFTs). But soluble amyloid-β (Aβ) oligomers have also been identified to accumulate in the brains of AD patients and correlate with cognitive dysfunction more than the extent of plaque deposition. Here, we developed an adeno-associated viral vector expressing the human mutated amyloid precursor protein (AAV-hAPP)...
December 20, 2016: Aging
https://www.readbyqxmd.com/read/27996964/multi-echo-fmri-replication-sample-of-autobiographical-memory-prospection-and-theory-of-mind-reasoning-tasks
#8
Elizabeth DuPre, Wen-Ming Luh, R Nathan Spreng
The default network is involved in self-generated thought, a class of cognition that includes autobiographical memory, prospection, and reasoning about the mental states of others. We collected a replication sample of Spreng and Grady (J Cogn. Neurosci. 22, 1112-1123, 2010), confirming that the default network differentially supports each of these forms of self-generated thought. Here we describe this dataset of multi-echo fMRI data in 31 young adults during autobiographical remembering, imagining, and mentalizing; we also provide an additional resting-state scan for each subject...
December 20, 2016: Scientific Data
https://www.readbyqxmd.com/read/27993231/neural-markers-in-pediatric-bipolar-disorder-and-familial-risk-for-bipolar-disorder
#9
Jillian Lee Wiggins, Melissa A Brotman, Nancy E Adleman, Pilyoung Kim, Caroline G Wambach, Richard C Reynolds, Gang Chen, Kenneth Towbin, Daniel S Pine, Ellen Leibenluft
OBJECTIVE: Bipolar disorder (BD) is highly heritable. Neuroimaging studies comparing unaffected youth at high familial risk for BD (i.e., those with a first-degree relative with the disorder; termed "high-risk" [HR]) to "low-risk" (LR) youth (i.e., those without a first-degree relative with BD) and to patients with BD may help identify potential brain-based markers associated with risk (i.e., regions where HR+BD≠LR), resilience (HR≠BD+LR), or illness (BD≠HR+LR). METHOD: During functional magnetic resonance imaging (fMRI), 99 youths (i...
January 2017: Journal of the American Academy of Child and Adolescent Psychiatry
https://www.readbyqxmd.com/read/27979789/age-related-reduction-of-bold-modulation-to-cognitive-difficulty-predicts-poorer-task-accuracy-and-poorer-fluid-reasoning-ability
#10
Jenny R Rieck, Karen M Rodrigue, Maria A Boylan, Kristen M Kennedy
Aging is associated with reduced resources needed to perform difficult cognitive tasks, but the neural underpinnings are not well understood, especially as there is scant evidence linking functional brain differences to aging cognition. Therefore, the current study examined modulation of fMRI activation from easier to harder spatial distance judgments across a large lifespan sample (N=161; ages 20-94) to identify when in the lifespan modulation to difficulty begins to show deficits and if age-related modulation predicts cognition...
February 15, 2017: NeuroImage
https://www.readbyqxmd.com/read/27918531/shared-memories-reveal-shared-structure-in-neural-activity-across-individuals
#11
Janice Chen, Yuan Chang Leong, Christopher J Honey, Chung H Yong, Kenneth A Norman, Uri Hasson
Our lives revolve around sharing experiences and memories with others. When different people recount the same events, how similar are their underlying neural representations? Participants viewed a 50-min movie, then verbally described the events during functional MRI, producing unguided detailed descriptions lasting up to 40 min. As each person spoke, event-specific spatial patterns were reinstated in default-network, medial-temporal, and high-level visual areas. Individual event patterns were both highly discriminable from one another and similar among people, suggesting consistent spatial organization...
January 2017: Nature Neuroscience
https://www.readbyqxmd.com/read/27913157/further-evidence-of-alerted-default-network-connectivity-and-association-with-theory-of-mind-ability-in-schizophrenia
#12
Omar Mothersill, Noreen Tangney, Derek W Morris, Hazel McCarthy, Thomas Frodl, Michael Gill, Aiden Corvin, Gary Donohoe
BACKGROUND: Resting-state functional magnetic resonance imaging (rs-fMRI) has repeatedly shown evidence of altered functional connectivity of large-scale networks in schizophrenia. The relationship between these connectivity changes and behaviour (e.g. symptoms, neuropsychological performance) remains unclear. METHODS: Functional connectivity in 27 patients with schizophrenia or schizoaffective disorder, and 25 age and gender matched healthy controls was examined using rs-fMRI...
November 29, 2016: Schizophrenia Research
https://www.readbyqxmd.com/read/27890008/functional-connectivity-analysis-of-brain-default-mode-networks-using-hamiltonian-path
#13
Zhuqing Jiao, Kai Ma, Huan Wang, Ling Zou, Jianbo Xiang
The aim of this study is to introduce Hamiltonian path to analyze functional connectivity of brain default mode networks (DMNs). Firstly, the brain DMNs in resting state are constructed with the employment of functional Magnetic Resonance Imaging (fMRI) data. Then, the Dijkstra algorithm is used to calculate the shortest path length of the node which represents each brain region, and the Hamiltonian path of the default network is solved through the improved adaptive ant colony algorithm. Finally, complex network analysis methods are introduced to discuss the node and network properties of brain functional connectivity in both normal subjects and stroke patients...
November 24, 2016: CNS & Neurological Disorders Drug Targets
https://www.readbyqxmd.com/read/27858329/saving-mental-effort-to-maintain-physical-effort-a-shift-of-activity-within-the-prefrontal-cortex-in-anticipation-of-prolonged-exercise
#14
Rémi Radel, Jeanick Brisswalter, Stéphane Perrey
Executive functioning and attention require mental effort. In line with the resource conservation principle, we hypothesized that mental effort would be saved when individuals expected to exercise for a long period. Twenty-two study participants exercised twice on a cycle ergometer for 10 min at 60% of their maximal aerobic power, with the expectation of exercising for either 10 min or 60 min. Changes in activity in the right dorsolateral prefrontal cortex (rdlPFC) and right medial frontal cortex (rmPFC) were investigated by measuring oxyhemoglobin using near-infrared spectroscopy...
November 17, 2016: Cognitive, Affective & Behavioral Neuroscience
https://www.readbyqxmd.com/read/27856733/spontaneous-default-network-activity-reflects-behavioral-variability-independent-of-mind-wandering
#15
Aaron Kucyi, Michael Esterman, Clay S Riley, Eve M Valera
The brain's default mode network (DMN) is highly active during wakeful rest when people are not overtly engaged with a sensory stimulus or externally oriented task. In multiple contexts, increased spontaneous DMN activity has been associated with self-reported episodes of mind-wandering, or thoughts that are unrelated to the present sensory environment. Mind-wandering characterizes much of waking life and is often associated with error-prone, variable behavior. However, increased spontaneous DMN activity has also been reliably associated with stable, rather than variable, behavior...
November 29, 2016: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/27836708/the-real-time-fmri-neurofeedback-based-stratification-of-default-network-regulation-neuroimaging-data-repository
#16
Amalia R McDonald, Jordan Muraskin, Nicholas T Van Dam, Caroline Froehlich, Benjamin Puccio, John Pellman, Clemens C C Bauer, Alexis Akeyson, Melissa M Breland, Vince D Calhoun, Steven Carter, Tiffany P Chang, Chelsea Gessner, Alyssa Gianonne, Steven Giavasis, Jamie Glass, Steven Homann, Margaret King, Melissa Kramer, Drew Landis, Alexis Lieval, Jonathan Lisinski, Anna Mackay-Brandt, Brittny Miller, Laura Panek, Hayley Reed, Christine Santiago, Eszter Schoell, Richard Sinnig, Melissa Sital, Elise Taverna, Russell Tobe, Kristin Trautman, Betty Varghese, Lauren Walden, Runtang Wang, Abigail B Waters, Dylan C Wood, F Xavier Castellanos, Bennett Leventhal, Stanley J Colcombe, Stephen LaConte, Michael P Milham, R Cameron Craddock
This data descriptor describes a repository of openly shared data from an experiment to assess inter-individual differences in default mode network (DMN) activity. This repository includes cross-sectional functional magnetic resonance imaging (fMRI) data from the Multi Source Interference Task, to assess DMN deactivation, the Moral Dilemma Task, to assess DMN activation, a resting state fMRI scan, and a DMN neurofeedback paradigm, to assess DMN modulation, along with accompanying behavioral and cognitive measures...
February 1, 2017: NeuroImage
https://www.readbyqxmd.com/read/27779908/states-of-mind-characterizing-the-neural-bases-of-focus-and-mind-wandering-through-dynamic-functional-connectivity
#17
Benjamin W Mooneyham, Michael D Mrazek, Alissa J Mrazek, Kaita L Mrazek, Dawa T Phillips, Jonathan W Schooler
During tasks that require continuous engagement, the mind alternates between mental states of focused attention and mind-wandering. Existing research has assessed the functional connectivity of intrinsic brain networks underlying the experience and training of these mental states using "static" approaches that assess connectivity across an entire task. To disentangle the different functional connectivity between brain regions that occur as the mind fluctuates between discrete brain states, we employed a dynamic functional connectivity approach that characterized brain activity using a sliding window...
October 25, 2016: Journal of Cognitive Neuroscience
https://www.readbyqxmd.com/read/27766641/physiological-and-neural-correlates-of-worry-and-rumination-support-for-the-contrast-avoidance-model-of-worry
#18
Elisa C K Steinfurth, Manuela G Alius, Julia Wendt, Alfons O Hamm
The current experiments tested neural and physiological correlates of worry and rumination in comparison to thinking about neutral events. According to the avoidance model-stating that worry is a strategy to reduce intense emotions-physiological and neurobiological activity during worried thinking should not differ from activation during neutral thinking. According to the contrast avoidance model-stating that worry is a strategy to reduce abrupt shifts of emotions-activity should be increased. To test these competing models, we induced worry and neutral thinking in healthy participants using personal topics...
February 2017: Psychophysiology
https://www.readbyqxmd.com/read/27749394/brain-connectivity-and-neurological-disorders-after-stroke
#19
Antonello Baldassarre, Lenny E Ramsey, Joshua S Siegel, Gordon L Shulman, Maurizio Corbetta
PURPOSE OF REVIEW: An important challenge in neurology is identifying the neural mechanisms underlying behavioral deficits after brain injury. Here, we review recent advances in understanding the effects of focal brain lesions on brain networks and behavior. RECENT FINDINGS: Neuroimaging studies indicate that the human brain is organized in large-scale resting state networks (RSNs) defined via functional connectivity, that is the temporal correlation of spontaneous activity between different areas...
December 2016: Current Opinion in Neurology
https://www.readbyqxmd.com/read/27687802/state-dependent-variability-of-dynamic-functional-connectivity-between-frontoparietal-and-default-networks-relates-to-cognitive-flexibility
#20
Linda Douw, Daniel G Wakeman, Naoaki Tanaka, Hesheng Liu, Steven M Stufflebeam
The brain is a dynamic, flexible network that continuously reconfigures. However, the neural underpinnings of how state-dependent variability of dynamic functional connectivity (vdFC) relates to cognitive flexibility are unclear. We therefore investigated flexible functional connectivity during resting-state and task-state functional magnetic resonance imaging (rs-fMRI and t-fMRI, resp.) and performed separate, out-of-scanner neuropsychological testing. We hypothesize that state-dependent vdFC between the frontoparietal network (FPN) and the default mode network (DMN) relates to cognitive flexibility...
December 17, 2016: Neuroscience
keyword
keyword
83900
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"