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Diffuse esophageal spasm

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https://www.readbyqxmd.com/read/27858325/is-poem-the-answer-for-management-of-spastic-esophageal-disorders-a-systematic-review-and-meta-analysis
#1
REVIEW
Muhammad Ali Khan, Vivek Kumbhari, Saowanee Ngamruengphong, Amr Ismail, Yen-I Chen, Yamile Haito Chavez, Majidah Bukhari, Richard Nollan, Mohammad Kashif Ismail, Manabu Onimaru, Valerio Balassone, Ahmed Sharata, Lee Swanstrom, Haruhiro Inoue, Alessandro Repici, Mouen A Khashab
BACKGROUND AND AIMS: Spastic esophageal disorders (SEDs) include spastic achalasia (type III), diffuse esophageal spasm (DES), and nutcracker/jackhammer esophagus (JH). Per-oral endoscopic myotomy (POEM) has demonstrated efficacy and safety in the treatment of achalasia. Recently, POEM has been indicated for the treatment of SEDs. We conducted a systematic review and meta-analysis to determine the clinical success and safety of POEM in SEDs. METHODS: We searched several databases from 01/01/2007 to 01/10/2016 to identify studies (with five or more patients) on POEM for the treatment of SEDs...
November 17, 2016: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/27833517/clinical-utility-of-esophageal-manometry-in-the-patients-with-dysphagia-experience-from-sudan
#2
Amin M Abbas, Sami Medani, Tajeldin M Abdallah, Gasim I Gasim
OBJECTIVES: The aim of this study was to assess the clinical utility of esophageal manometry among Sudanese patients presenting to the National Centre for Gastrointestinal and Liver Diseases, Ibn Sina Hospital, Khartoum, Sudan. METHODOLOGY: Consecutive patients referred for esophageal manometry at the aforementioned center from July 2008 through January 2011 were included in the study. Manometric studies were done after stopping medicines with a known effect on esophageal motility and an overnight fast...
October 2016: International Journal of Health Sciences
https://www.readbyqxmd.com/read/27832322/corkscrew-esophagus
#3
REVIEW
Eduardo Kaiser Ururahy Nunes Fonseca, Fernando Ide Yamauchi, Cassia Franco Tridente, Ronaldo Hueb Baroni
Corkscrew esophagus (also referred as rosary bead esophagus) is a classic finding of diffuse esophageal spasm (DES) in barium studies reflecting abnormal contractions, leading to compartmentalization and curling of the esophagus, ultimately giving an appearance similar to a corkscrew or rosary beads. We review the pathophysiology of this finding, correlating it to corkscrew and rosary images that originated this classic description.
November 10, 2016: Abdominal Radiology
https://www.readbyqxmd.com/read/27699951/muscle-layer-histopathology-and-manometry-pattern-of-primary-esophageal-motility-disorders-including-achalasia
#4
N Nakajima, H Sato, K Takahashi, G Hasegawa, K Mizuno, S Hashimoto, Y Sato, S Terai
BACKGROUND: Histopathology of muscularis externa in primary esophageal motility disorders has been characterized previously. We aimed to correlate the results of high-resolution manometry with those of histopathology. METHODS: During peroral endoscopic myotomy, peroral esophageal muscle biopsy was performed in patients with primary esophageal motility disorders. Immunohistochemical staining for c-kit was performed to assess the interstitial cells of Cajal (ICCs)...
October 3, 2016: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/27526295/lymphocytic-esophagitis-in-nonachalasia-primary-esophageal-motility-disorders-improved-criteria-prevalence-strength-of-association-and-natural-history
#5
Juan Putra, Kristen E Muller, Zilla H Hussain, Siddhartha Parker, Scott Gabbard, Elizabeth B Brickley, Brian E Lacy, Richard Rothstein, Mikhail Lisovsky
Lymphocytic esophagitis (LE) is a histologic pattern with no established clinical correlates in the majority of patients. The goal of this study was to evaluate the association between nonachalasia primary esophageal motility disorders (PEMD) and LE. Sixty-nine patients with PEMD and esophageal biopsies, including 22 with nutcracker esophagus, 33 with ineffective motility, and 14 with diffuse spasm, constituted the study group. The control group consisted of 70 patients with severe dysmotility-negative gastroesophageal reflux disease requiring referral for Nissen fundoplication...
August 11, 2016: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/27036895/poem-the-prototypical-new-notes-procedure-and-first-successful-notes-procedure
#6
REVIEW
Robert Bechara, Haruhiro Inoue
Peroral endoscopic myotomy (POEM) was first performed in 2008 as a novel treatment of achalasia. It is now performed globally, demonstrating the evolution of the first successful natural orifice transluminal endoscopic surgery (NOTES) procedure. There is extensive data demonstrating the safety and efficacy of POEM, and now long-term data has emerged demonstrating that the efficacy is durable. POEM is also being used to successfully treat diffuse esophageal spasm (DES) and jackhammer esophagus. With jackhammer esophagus and DES, inclusion of the lower esophageal sphincter in the myotomy minimizes the risk of symptom development from iatrogenic ineffective esophageal motility...
April 2016: Gastrointestinal Endoscopy Clinics of North America
https://www.readbyqxmd.com/read/26839649/submucosal-tunnel-endoscopy-peroral-endoscopic-myotomy-and-peroral-endoscopic-tumor-resection
#7
REVIEW
Nikolas Eleftheriadis, Haruhiro Inoue, Haruo Ikeda, Manabu Onimaru, Roberta Maselli, Grace Santi
Peroral endoscopic myotomy (POEM) is an innovative, minimally invasive, endoscopic treatment for esophageal achalasia and other esophageal motility disorders, emerged from the natural orifice transluminal endoscopic surgery procedures, and since the first human case performed by Inoue in 2008, showed exciting results in international level, with more than 4000 cases globally up to now. POEM showed superior characteristics than the standard 100-year-old surgical or laparoscopic Heller myotomy (LHM), not only for all types of esophageal achalasia [classical (I), vigorous (II), spastic (III), Chicago Classification], but also for advanced sigmoid type achalasia (S1 and S2), failed LHM, or other esophageal motility disorders (diffuse esophageal spasm, nutcracker esophagus or Jackhammer esophagus)...
January 25, 2016: World Journal of Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/26275635/esophageal-motility-in-eosinophilic-esophagitis
#8
A H Weiss, N Iorio, R Schey
BACKGROUND: Eosinophilic esophagitis (EoE) is characterized by eosinophilic infiltration of the esophagus and is a potential cause of dysphagia and food impaction, most commonly affecting young men. Esophageal manometry findings vary from normal motility to aperistalsis, simultaneous contractions, diffuse esophageal spasm, nutcracker esophagus or hypotonic lower esophageal sphincter (LES). It remains unclear whether esophageal dysmotility plays a significant role in the clinical symptoms of EoE...
July 2015: Revista de Gastroenterología de México
https://www.readbyqxmd.com/read/26143577/esophageal-epiphrenic-diverticulum-associated-with-diffuse-esophageal-spasm
#9
Hideo Matsumoto, Hisako Kubota, Masaharu Higashida, Noriaki Manabe, Ken Haruma, Toshihiro Hirai
INTRODUCTION: Esophageal diverticulum, a relatively rare condition, has been considered to be associated with motor abnormalities such as conditions that cause a lack of coordination between the distal esophagus and lower esophageal sphincter. PRESENTATION OF CASE: We herein report a case of esophageal epiphrenic diverticulum associated with diffuse esophageal spasm. A 73-year-old woman presented with dysphagia and regurgitation. Imaging examinations revealed a right-sided esophageal diverticulum located about 10cm above the esophagogastric junction...
2015: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/26134191/a-patient-with-vigorous-achalasia-and-rapid-enlargement-of-an-epiphrenic-esophageal-diverticulum
#10
Yasuhiro Tamura, Yasushi Funaki, Kazuori Adachi, Hisatsugu Noda, Shinya Izawa, Akihito Iida, Naotaka Ogasawara, Masahiko Miyaji, Makoto Sasaki, Kunio Kasugai
A 47-year-old man was found to have a 3-cm epiphrenic esophageal diverticulum on an upper gastrointestinal (UGI) barium study. He developed the symptoms of heartburn approximately 12 months later. UGI endoscopy indicated non-erosive gastroesophageal reflux disease (NERD) and an epiphrenic esophageal diverticulum. A proton pump inhibitor (PPI) did not relieve the symptoms. An UGI barium study at that time showed that the epiphrenic esophageal diverticulum had enlarged to 7 cm, and esophageal manometry showed findings of achalasia and diffuse esophageal spasm (DES), thus vigorous achalasia was diagnosed...
2015: Internal Medicine
https://www.readbyqxmd.com/read/26119796/a-spiraling-case-of-persistent-dysphagia-diffuse-esophageal-spasm
#11
Dhyanesh A Patel, Michael F Vaezi
No abstract text is available yet for this article.
August 2015: Gastroenterology
https://www.readbyqxmd.com/read/26087632/-clinical-and-pathogenetic-features-of-esophageal-spasm
#12
COMPARATIVE STUDY
L D Firsova, I M Pichugina, O B Ianova, O I Berezina, D S Bordin
AIM: To comparatively analyze clinical manifestations in patients with primary esophageal spasm (ES) and its concurrence with gastroesophageal reflux disease (GERD) and the results of their instrumental examinations and psychodiagnostic tests. SUBJECTS AND METHODS: A total of 104 patients with the clinical and manometric signs of ES were examined and divided into two groups: 1) 42 patients with primary ES; 2) 62 patients with ES concurrent with GERD. The examination encompassed esophageal manometry, esophagogastroduodenoscopy, 24-hour pH metry, and an interview using a questionnaire to identify autonomic disorders, and the Mini-Mult test...
2015: Terapevticheskiĭ Arkhiv
https://www.readbyqxmd.com/read/25987921/rare-radiological-pattern-of-diffuse-esophageal-spasm
#13
Demis N Lipe, Nathan Borden
No abstract text is available yet for this article.
May 2015: Western Journal of Emergency Medicine
https://www.readbyqxmd.com/read/25940142/-esophageal-motility-disorders
#14
REVIEW
M Müller, I Gockel
Esophageal motility disorders are a group of diseases that result in swallowing dysfunction due to changes in neuromuscular structures, which coordinate esophageal function. Besides achalasia, which is the best defined functional disturbance of the esophagus, there are other motility disorders, namely hypercontractile (diffuse esophageal spasm, nutcracker or jackhammer esophagus, hypertensive lower esophageal sphincter) and hypocontractile disorders, whose origins and disease mechanisms are not yet well understood...
June 2015: Der Internist
https://www.readbyqxmd.com/read/25861066/clinical-endoscopic-and-manometric-features-of-the-primary-motor-disorders-of-the-esophagus
#15
Júlio César Martinez, Gustavo Rosa de Almeida Lima, Diego Henrique Silva, Alexandre Ferreira Duarte, Neil Ferreira Novo, Ernesto Carlos da Silva, Pérsio Campos Correia Pinto, Alexandre Moreira Maia
BACKGROUND: Significant incidence, diagnostic difficulties, clinical relevance and therapeutic efficacy associated with the small number of publications on the primary esophageal motor disorders, motivated the present study. AIM: To determine the manometric prevalence of these disorders and correlate them to the endoscopic and clinical findings. METHODS: A retrospective study of 2614 patients, being 1529 (58.49%) women and 1085 (41.51%) men...
2015: Arquivos Brasileiros de Cirurgia Digestiva: ABCD, Brazilian Archives of Digestive Surgery
https://www.readbyqxmd.com/read/25835105/a-functional-study-of-the-esophagus-in-patients-with-non-cardiac-chest-pain-and-dysphagia
#16
Roberto Gullo, Angela Inviati, Piero Luigi Almasio, Valentina Di Paola, Silvia Di Giovanni, Gregorio Scerrino, Gaspare Gulotta, Sebastiano Bonventre
BACKGROUND/AIMS: Nutcracker esophagus and non-specific motility disorders are the main causes of non-cardiac chest pain (NCCP), with gastroesophageal reflux in 60% of cases. Achalasia and diffuse esophageal spasm are the most frequent anomalies described in patients with dysphagia. The goal of this study was to evaluate the occurrence of esophageal body and lower esophageal sphincter motor abnormalities in patients with dysphagia, NCCP, or both. MATERIALS AND METHODS: This study is a retrospective analysis of 716 patients with NCCP and/or dysphagia tested between January 1994 and December 2010...
March 2015: Turkish Journal of Gastroenterology: the Official Journal of Turkish Society of Gastroenterology
https://www.readbyqxmd.com/read/25775289/-diffuse-oesophageal-spasms-results-of-a-retrospective-manometric-study
#17
Serghini Meriem, Ben Kahla Sabeh, Karoui Sami, Kallel Lamia, Matri Samira, Ben Mustapha Nadia, Fekih Monia, Boubaker Jalel, Filali Azza
BACKGROUND: Diffuse esophageal spasms is a primary motor disrder of the esophagus of unknown etiology characterized by intermettent peristalsis. This is rare condition which represents 3-5% if primary disorders of the esophagus. Diagnosis and treatment of this entity are difficult. AIMS: To evaluate the frequency and the clinical and the manometric features of diffuse esophageal spasms. METHODS: We conducted a retrospective study related to esophageal manometry performed between January 2000 and December 2011 regardless of the indication...
July 2014: La Tunisie Médicale
https://www.readbyqxmd.com/read/25634487/international-multicenter-experience-with-peroral-endoscopic-myotomy-for-the-treatment-of-spastic-esophageal-disorders-refractory-to-medical-therapy-with-video
#18
MULTICENTER STUDY
Mouen A Khashab, Ahmed A Messallam, Manabu Onimaru, Ezra N Teitelbaum, Michael B Ujiki, Matthew E Gitelis, Rani J Modayil, Eric S Hungness, Stavros N Stavropoulos, Mohamad H El Zein, Hironari Shiwaku, Rastislav Kunda, Alessandro Repici, Hitomi Minami, Philip W Chiu, Jeffrey Ponsky, Vivek Kumbhari, Payal Saxena, Amit P Maydeo, Haruhiro Inoue
BACKGROUND: Limited data exist on the use of peroral endoscopic myotomy (POEM) for therapy of spastic esophageal disorders (SEDs). OBJECTIVE: To study the efficacy and safety of POEM for the treatment of patients with diffuse esophageal spasm, jackhammer esophagus, or type III (spastic) achalasia. DESIGN: Retrospective study. SETTING: International, multicenter, academic institutions. PATIENTS: All patients who underwent POEM for treatment of SEDs refractory to medical therapy at 11 centers were included...
May 2015: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/25632912/evaluation-of-proton-pump-inhibitor-resistant-nonerosive-reflux-disease-by-esophageal-manometry-and-24-hour-esophageal-impedance-and-ph-monitoring
#19
Osamu Kawamura, Hiroko Hosaka, Yasuyuki Shimoyama, Akiyo Kawada, Shiko Kuribayashi, Motoyasu Kusano, Masanobu Yamada
BACKGROUND: Patients with proton pump inhibitor (PPI)-resistant nonerosive reflux disease (NERD) include subgroups that have markedly different pathophysiology. This study aimed to clarify the pathophysiology of NERD by esophageal manometry with 24-hour esophageal impedance and pH monitoring. METHODS: Eighteen consecutive outpatients referred to our expert center for functional gastrointestinal motility with suspected PPI-resistant NERD were enrolled. Manometry was performed to detect esophageal motility disorders...
2015: Digestion
https://www.readbyqxmd.com/read/25626933/dysphagia-after-antireflux-fundoplication-endoscopic-radiological-and-manometric-evaluation
#20
Drausio Jeferson Morais, Luiz Roberto Lopes, Nelson Adami Andreollo
BACKGROUND: The transient dysphagia after fundoplication is common and most often disappears until six weeks postoperatively. AIM: Analyze a group of patients who presented late and persistent dysphagia postoperatively. METHODS: Forty-one patients after Nissen fundoplication, 14 male and 27 female, mean age 48 year, were evaluated based on medical history, esophagogastroduodenoscopy, contrast radiographic examination and esophageal manometry...
November 2014: Arquivos Brasileiros de Cirurgia Digestiva: ABCD, Brazilian Archives of Digestive Surgery
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