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https://www.readbyqxmd.com/read/28938268/surgical-and-survival-outcomes-following-pelvic-exenteration-for-locally-advanced-primary-rectal-cancer-results-from-an-international-collaboration
#1
(no author information available yet)
OBJECTIVE: The aim of the study was to analyze data from an international collaboration, and ascertain prognostic indicators that inform clinical decision-making and practices regarding the role of pelvic exenteration for locally advanced primary rectal cancer (LARC). BACKGROUND: With improved national screening programs fewer patients present with LARC. Despite this, select cohorts of patients require pelvic exenteration. To date, the majority of outcome data are from single-center series...
September 21, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28936637/significant-prognostic-factors-affecting-treatment-outcomes-of-salivary-gland-carcinoma-a-multicenter-retrospective-analysis
#2
Shin-Ichi Yamada, Hiroshi Kurita, Takahiro Kamata, Tadaaki Kirita, Michihiro Ueda, Tetsuro Yamashita, Yoshihide Ota, Mitsunobu Otsuru, Nobuhiro Yamakawa, Masaya Okura, Tomonao Aikawa, Masahiro Umeda
The purpose of this study was to investigate the prognostic factor in salivary gland carcinoma patients. Clinical and pathological data of 211 consecutive patients who treated with curative intent were analyzed. The overall survival (OS) rate, local control rate, and distant metastasis rate were calculated. To examine a prognostic factor in salivary gland carcinoma patients, a multivariate analysis was performed. The 5-year-OS rate was 84.0%, and 10-year was 69.2%. The 5-year-local control rate was 84.6%, and 10-year was 70...
September 21, 2017: Odontology
https://www.readbyqxmd.com/read/28936478/recurrence-rate-of-melanoma-in-situ-when-treated-with-serial-disk-staged-excision-a-case-series
#3
Daniel Garcia, Robert E Eilers, S Brian Jiang
BACKGROUND: Cutaneous melanoma is one of the fastest rising cancer diagnoses in recent years. Melanoma in situ (MIS) constitutes a large proportion of all diagnosed melanomas. While surgical excision is considered the standard of therapy, the literature is not clear on which surgical technique minimizes local recurrence. A common technique is serial staged excision (SSE), in which a series of mapped excisions are made according to histopathological examination of tissue. Previously published recurrence rates for SSE ranges from 0-12%, over a range of 4...
February 2017: Journal of Clinical and Investigative Dermatology
https://www.readbyqxmd.com/read/28935510/intraoperative-computed-tomography-navigation-during-thoracoscopic-segmentectomy-for-small-sized-lung-tumors
#4
Sung Soo Chang, Taku Okamoto, Yoshimasa Tokunaga, Takayuki Nakano
Performance of thoracoscopic pulmonary segmentectomy for primary lung cancer or pulmonary metastases has recently increased. In patients with emphysema, identification of the intersegmental line is often difficult. For nonpalpable lesions, securing a sufficient surgical margin is more likely to be uncertain. The purpose of this study was to evaluate the efficacy of intraoperative computed tomography (CT) scan during video-assisted thoracoscopic surgery (VATS) pulmonary segmentectomy. This study included 12 patients who underwent intraoperative CT-assisted VATS segmentectomy between January 2015 and August 2016...
August 24, 2017: Seminars in Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28935487/clinical-prognostic-factors-of-salivary-adenoid-cystic-carcinoma-a%C3%A2-single-center-analysis-of-61-patients
#5
Robert Cordesmeyer, Henning Schliephake, Philipp Kauffmann, Markus Tröltzsch, Rainer Laskawi, Philipp Ströbel, Felix Bremmer
PURPOSE: Adenoid cystic carcinomas are rare malignant tumors of the salivary glands. They are characterized by a high rate of local recurrence, late distant metastasis and a poor disease-free survival. In this study, we analyzed a series of 61 patients who were all treated at the University of Göttingen over a period of 21.0 years. MATERIALS AND METHODS: In all 61 patients with salivary adenoid cystic carcinoma, clinical data, demographic data, risk factors, tumor location, tumor stage, status of surgical margin, surgical treatment, postoperative radiotherapy and follow-up interval were assessed...
August 10, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/28935274/a-matter-of-margins-surgical-and-pathologic-risk-factors-for-recurrence-in-extramammary-paget-s-disease
#6
Beverly Long, Adam R Schmitt, Amy L Weaver, Michaela McGree, Jamie N Bakkum-Gamez, Jerry Brewer, William A Cliby
OBJECTIVES: To determine surgical and pathologic variables associated with recurrence in extramammary Paget's disease (EMPD). METHODS: Medical records of patients seeking care for EMPD from 1/1992-9/2015 were reviewed. Follow-up was restricted to 5years following primary surgery. Recurrence-free survival (RFS) was estimated using the Kaplan-Meier method. Risk factors were evaluated for an association with recurrence and positive margins, respectively, using Cox proportional hazards regression and logistic regression...
September 18, 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/28932727/effectiveness-of-cholangioscopy-using-narrow-band-imaging-for-hepatobiliary-malignancies
#7
Ji Woong Jang, Dong Hyo Noh, Kyu-Hyun Paik, Sae Hee Kim, Il-Hyun Paik, Sung Hee Jung
PURPOSE: Recently, cholangioscopy using narrow band imaging (NBI) has been used as a diagnostic modality for better visualization in hepatobiliary malignancies; however, there are few reports on it. Our aim is to evaluate the effectiveness of cholangioscopy using NBI in hepatobiliary malignancies. METHODS: Between January 2007 and December 2016, 152 cholangioscopies using percutaneous approach were conducted in total 123 patients. Among these, 36 patients were suspicious of hepatobiliary malignancies...
September 2017: Annals of Surgical Treatment and Research
https://www.readbyqxmd.com/read/28932344/-a-pink-nodule-on-the-face
#8
Amina Kissou, Badredine Hassam
We report the case of a 32-year old female patient, with no notable medical history, requiring dermatology consultation for evaluation of a nodule on her right cheek which had evolved over the past 10 years. Clinical examination showed a reddish dermal-based nodule with a smooth surface. The lesion measured 1cm in diameter and was located at the level of the right cheek (A). There was no adenopathy and the remainder of the clinical examination was normal. The patient underwent skin biopsy which showed tumor proliferation composed of fusiform cells with poorly limited eosinophilic cytoplasm and lightly atypical elongated nuclei without mitosis and with mononuclear inflammatory cell infiltrate at the level of the dermis...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28930903/effects-of-localized-cold-therapy-on-pain-in-postoperative-spinal-fusion-patients-a-randomized-control-trial
#9
Patricia Quinlan, Jack Davis, Kara Fields, Pia Madamba, Lisa Colman, Daniela Tinca, Regina Cannon Drake
BACKGROUND: Cold therapy used in the sports medicine settings has been found to be effective in reducing postoperative pain; however, there are limited studies that examine the effect of cold therapy on postoperative pain in patients with posterior lumbar spinal fusion. PURPOSE: The purpose of this study was to determine the effects of cold on postoperative spine pain and add to the body of knowledge specific to practical application of cold therapy in the spine surgery setting...
September 2017: Orthopaedic Nursing
https://www.readbyqxmd.com/read/28930050/tattooing-or-not-a-review-of-current-practice-and-outcomes-for-laparoscopic-colonic-resection-following-endoscopy-at-a-tertiary-care-centre
#10
François Letarte, Mitch Webb, Manoj Raval, Ahmer Karimuddin, Carl J Brown, P Terry Phang
BACKGROUND: Because small colonic tumours may not be visualized or palpated during laparoscopy, location of the lesion must be identified before surgery. The aim of this study was to evaluate the effectiveness of the current recommendation of endoscopic tattooing of lesions prior to laparoscopic colonic resections. METHODS: All consecutive patients who underwent elective laparoscopic resection for a colonic lesion at a single tertiary institution between 2013 and 2015 were identified for chart review...
October 1, 2017: Canadian Journal of Surgery. Journal Canadien de Chirurgie
https://www.readbyqxmd.com/read/28928852/dcis-margins-and-breast-conservation-md-anderson-cancer-center-multidisciplinary-practice-guidelines-and-outcomes
#11
REVIEW
Henry M Kuerer, Benjamin D Smith, Mariana Chavez-MacGregor, Constance Albarracin, Carlos H Barcenas, Lumarie Santiago, Mary E Edgerton, Gaiane M Rauch, Sharon H Giordano, Aysegul Sahin, Savitri Krishnamurthy, Wendy Woodward, Debasish Tripathy, Wei T Yang, Kelly K Hunt
Recent published guidelines suggest that adequate margins for DCIS should be ≥ 2 mm after breast conserving surgery followed by radiotherapy (RT). Many groups now use this guideline as an absolute indication for additional surgery. This article describes detailed multidisciplinary practices including extensive preoperative/intraoperative pathologic/histologic image-guided assessment of margins, offering some patients with small low/intermediate grade DCIS no RT, the use/magnitude of radiation boost tailoring to margin width, and endocrine therapy for ER-positive DCIS...
2017: Journal of Cancer
https://www.readbyqxmd.com/read/28928327/the-technique-of-laparoscopic-hepatic-bisegmentectomy-with-regional-lymphadenectomy-for-gallbladder-cancer
#12
Hirdaya H Nag, Prithivi Raj, Kshitij Sisodia
BACKGROUND: Laparoscopic hepatic bisegmentectomy (s4b and s5) with regional lymphadenectomy (LHBRL) for patients with gallbladder cancer (GBC) is rarely reported. AIMS: The aim of the study was to describe the technique of LHBRL in patients with GBC and to present our initial experience. PATIENTS AND METHODS: This retrospective study was conducted on twenty patients with GBC who were considered for LHBRL by the described technique. These patients either had a suspicion of GBC (SGBC) or had an incidental diagnosis of GBC (IGBC)...
September 20, 2017: Journal of Minimal Access Surgery
https://www.readbyqxmd.com/read/28928013/the-prognostic-relevance-of-parapyloric-lymph-node-metastasis-in-siewert-type-ii-iii-adenocarcinoma-of-the-esophagogastric-junction
#13
Jia-Bin Wang, Man-Qiang Lin, Ping Li, Jian-Wei Xie, Jian-Xian Lin, Jun Lu, Qi-Yue Chen, Long-Long Cao, Mi Lin, Chao-Hui Zheng, Chang-Ming Huang
BACKGROUND: The purpose of this study was to evaluate the prognosis of patients with Siewert type II/III adenocarcinoma of the esophagogastric junction (AEG) with parapyloric lymph node (No. 5 and 6 lymph nodes, PLN) metastasis and to determine the need for PLN dissection for patients with type II/III AEG. METHODS: A total of 1008 patients with type II/III AEG who underwent a transabdominal total gastrectomy were enrolled. The long-term surgical outcome of PLN-positive patients and the therapeutic value of PLN dissection were analyzed...
September 8, 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28928011/perioperative-therapies-enhancing-the-impact-of-cancer-surgery-with-repurposed-drugs
#14
EDITORIAL
Pan Pantziarka, Gauthier Bouche, Richard Sullivan, André M Ilbawi, Anna J Dare, Lydie Meheus
Surgical resection remains the major modality for modern curative treatment for solid tumours. However, post-surgical recurrence, even following clear-margin resection and adjuvant treatment, remains common in many types of cancer. Reducing recurrence rates, therefore, offers the potential to increase cure rates and increase overall survival. Perioperative therapies, simple interventions during the perioperative period, are designed to address some of the factors which influence post-surgical recurrence. A range of perioperative therapies are introduced and the rationale for further clinical investigation outlined...
September 7, 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28927783/surgical-resection-of-locally-recurrent-renal-cell-carcinoma-after-nephrectomy-oncological-outcome-and-predictors-of-survival
#15
Roman Herout, Johannes Graff, Angelika Borkowetz, Stefan Zastrow, Steffen Leike, Rainer Koch, Desiree-Louise Draeger, Chris Protzel, Oliver W Hakenberg, Manfred P Wirth, Michael Froehner
OBJECTIVE: To describe the course of disease of patients surgically treated for locally recurrent renal cell carcinoma (LRRCC) after nephrectomy and to identify potential predictive factors for long-term survival. PATIENTS AND METHODS: We, retrospectively, identified 54 patients who underwent surgical resection of LRRCC after open nephrectomy for localized kidney cancer. The median age at time of surgery for LRRCC was 65 years. Survival rates were determined with the Kaplan-Meier method...
September 15, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/28927743/does-a-mandibular-access-osteotomy-improve-survival-in-pt2-oral-tongue-cancers-retrospective-study-at-a-single-institution
#16
H S Ong, S Gokavarapu, Z Tian, J Li, W Cao, C P Zhang
The surgical approach to the resection of oral tongue cancers can involve transoral resection (TOR) or a temporary mandibulotomy access (TMA). There are no relevant guidelines, and the oncological safety of TOR needs consideration. The objective of this study was to investigate TMA and TOR in pT2 oral tongue cancer surgery with regard to cancer outcomes. Demographic, surgical, and histology data from primary pT2 tongue cancers were recorded and evaluated through multivariate Cox regression for local recurrence (LR), disease-free survival (DFS), and overall survival (OS)...
September 15, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28927740/comparative-evaluation-of-iodine-125-radioactive-seed-localization-and-wire-localization-for-resection-of-breast-lesions
#17
Vi Thuy Tran, Julie David, Erica Patocskai, Mathieu Zummo-Soucy, Rami Younan, Lucie Lalonde, Maude Labelle, Mona El Khoury, André Robidoux, Isabelle Trop
PURPOSE: Radioactive seed localization (RSL) uses a titanium seed labeled with iodine-125 energy for surgery of nonpalpable breast lesions. RSL facilitates radiology-surgery scheduling and allows for improved oncoplasty compared with wire localization (WL). The purpose of this work was to compare the 2 techniques. METHODS: We performed a retrospective study of all breast lesions operated with RSL between February 2013 and March 2015 at our university institution, and compared with an equivalent number of surgeries performed with a single WL...
September 15, 2017: Canadian Association of Radiologists Journal, Journal L'Association Canadienne des Radiologistes
https://www.readbyqxmd.com/read/28927038/effects-of-neoadjuvant-chemotherapy-combined-with-radiotherapy-in-patients-with-advanced-esophageal-carcinoma
#18
Yu Liu, Deyao Xie, Chang Li, Chaoxi Lin, Jun Zhao
We analyzed the improvement of survival time and the effects of neoadjuvant chemotherapy combined with radiotherapy on treating patients with advanced esophageal carcinoma. Retrospectively, 43 patients were selected with esophageal carcinoma who were administered neoadjuvant chemotherapy combined with radiotherapy. According to gender, and tumor staging, the nearest neighbor matching was carried out. Eighty-six patients (1:2) who received neoadjuvant chemotherapy and 129 patients (1:3) who underwent surgery only were taken and compared for clinical outcomes...
September 2017: Oncology Letters
https://www.readbyqxmd.com/read/28926665/the-value-of-the-frontalis-suspension-procedure-as-a-repeat-intervention-in-congenital-blepharoptosis
#19
Özlem Ural, Mehmet C Mocan, Ugur Erdener
PURPOSE: To evaluate the therapeutic benefits of frontalis suspension as a repeat intervention in congenital blepharoptosis. METHODS: Pediatric patients diagnosed as having congenital ptosis who had at least 2 years of postoperative follow-up were included in this retrospective study. A successful outcome was defined as a postoperative margin-reflex distance of 3 mm or greater. The chi-square, Student's t, and Mann-Whitney U tests were used in comparisons. RESULTS: Eighty-four eyes of 77 patients with a follow-up period of 8...
September 1, 2017: Journal of Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/28925783/laparoscopic-assisted-resection-for-advanced-colorectal-cancer-in-solid-organ-transplant-recipients
#20
Ze-Nan Xia, Rui Hou, Wei Zhu, Ru Yao, Zhao Lu, Hui-Zhong Qiu, Guo-Le Lin
AIM: To evaluate the feasibility, short- and long-term outcomes, and safety of laparoscopic resection for advanced colorectal cancer (CRC) in solid organ transplant recipients. METHODS: Between September 2001 and April 2016, five patients who underwent laparoscopic-assisted resection for CRC after solid organ transplantation were included in this study. Their clinical data were retrospectively analyzed with regard to patient demographics, immunosuppressive therapy, tumor characteristics, surgical outcomes, and follow-up data...
September 19, 2017: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
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