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https://www.readbyqxmd.com/read/28324913/tests-for-informative-cluster-size-using-a-novel-balanced-bootstrap-scheme
#1
Jaakko Nevalainen, Hannu Oja, Somnath Datta
Clustered data are often encountered in biomedical studies, and to date, a number of approaches have been proposed to analyze such data. However, the phenomenon of informative cluster size (ICS) is a challenging problem, and its presence has an impact on the choice of a correct analysis methodology. For example, Dutta and Datta (2015, Biometrics) presented a number of marginal distributions that could be tested. Depending on the nature and degree of informativeness of the cluster size, these marginal distributions may differ, as do the choices of the appropriate test...
March 21, 2017: Statistics in Medicine
https://www.readbyqxmd.com/read/28324814/risk-of-injury-from-alcohol-marijuana-and-other-drug-use-among-emergency-department-patients
#2
Cheryl J Cherpitel, Yu Ye, Gabriel Andreuccetti, Tim Stockwell, Kate Vallance, Clifton Chow, Jeffrey R Brubacher
BACKGROUND: Alcohol is known to be associated with injury, but little is known of combined use of alcohol and other drugs on injury; especially important for marijuana, given increasing legalization of use in the U.S. and Canada. METHODS: Probability samples of patients 18 and older were interviewed in the emergency department at two sites in Vancouver and one in Victoria, BC (n=1191 injured and 1613 non-injured patients). Case-control and case-crossover analyses were used to analyze risk of injury, based on self-reported alcohol and drug use (marijuana, stimulants, depressants) prior to injury...
March 7, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28324710/dual-substrate-limitation-modeling-and-implications-for-mainstream-deammonification
#3
Heather A Stewart, Ahmed Al-Omari, Charles Bott, Haydee De Clippeleir, Chunyang Su, Imre Takacs, Bernhard Wett, Arash Massoudieh, Sudhir Murthy
Substrate limitation occurs frequently in wastewater treatment and knowledge about microbial behavior at limiting conditions is essential for the use of biokinetic models in system design and optimization. Monod kinetics are well-accepted for modeling growth rates when a single substrate is limiting, but several models exist for treating two or more limiting substrates simultaneously. In this study three dual limitation models (multiplicative, minimum, and Bertolazzi) were compared based on experiments using nitrite-oxidizing bacteria (limited by dissolved oxygen and nitrite) and ANaerobic AMMonia-OXidizing bacteria or Aanammox (limited by ammonium and nitrite) within mixed liquor from deammonification pilots...
March 9, 2017: Water Research
https://www.readbyqxmd.com/read/28324188/autobiographical-memory-loss-following-a-right-prefrontal-lobe-tumour-resection-a-case-report-and-review-of-the-literature
#4
A A B Jamjoom, P Gallo, J Kandasamy, J Phillips, D Sokol
INTRODUCTION: The right prefrontal lobe has not traditionally been considered eloquent brain. Resection of tumours within this region does not typically lead to permanent functional impairment. In this report, we highlight the case of a patient who developed autobiographical memory loss following an uncomplicated resection of a right prefrontal tumour. CASE MATERIAL: A previously fit and well 15-year old presented with a persistent right-sided headache. An MRI demonstrated an expanded right mid-frontal gyrus with changes consistent with a low-grade tumour...
March 21, 2017: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/28324185/diameters-and-bone-thickness-at-the-margin-of-the-foramen-magnum-in-dry-skulls-from-pediatric-population-a-cross-sectional-anatomical-study
#5
Marina Raguz, Pero Hrabac, Dora Sedmak, Miroslav Gjurasin, Natasa Kovacic
PURPOSE: The purpose of the study was to estimate the size and bone thickness at the margin of the foramen magnum in a pediatric population. METHODS: Sixty occipital bone specimens from the collection of macerated skulls at the Department of Anatomy, University of Zagreb, were examined and measured using a vernier scale/caliper. For the purpose of analysis, specimens were divided into two age groups: 1-6 years and 7-18 years of age (before and after the fusion of ossification centers in the occipital bone)...
March 21, 2017: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/28324164/novel-intraoperative-use-of-the-tensipresser-to-assess-factors-predictive-of-pancreatic-fistula-after-pancreaticoduodenectomy
#6
Manabu Mikamori, Kunihito Gotoh, Hidenori Takahashi, Hirofumi Akita, Akira Tomokuni, Shogo Kobayashi, Masayuki Ohue, Yoshiyuki Fujiwara, Masahiko Yano, Osamu Ishikawa, Masato Sakon
PURPOSES: Pancreatic fistula (PF) is a challenging complication of pancreaticoduodenectomy (PD). 'Soft pancreas' is reported as a risk factor for PF; however, palpation by the surgeon is not an objective method of evaluating pancreatic texture. We conducted this study to investigate whether a texture analyzer called a "Tensipresser" can be used to quantify pancreatic tissue hardness and predict the development of postoperative PF. METHODS: We assessed pancreatic texture in 85 patients who underwent PD...
March 21, 2017: Surgery Today
https://www.readbyqxmd.com/read/28324161/thermal-ecology-of-three-coexistent-desert-lizards-implications-for-habitat-divergence-and-thermal-vulnerability
#7
Shu-Ran Li, Yang Wang, Liang Ma, Zhi-Gao Zeng, Jun-Huai Bi, Wei-Guo Du
How ectotherms exploit thermal resources has important implications for their habitat utilization and thermal vulnerability to climate warming. To address this issue, we investigated thermal relations of three sympatric lizard species (Eremias argus, Eremias multiocellata, and Phrynocephalus przewalskii) in the desert steppe of Inner Mongolia, China. We determined the thermoregulatory behavior, body temperature (T b), operative temperature (T e), selected body temperature (T sel), and critical thermal maximum (CTmax) of adult lizards...
March 21, 2017: Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology
https://www.readbyqxmd.com/read/28324130/the-oblique-popliteal-ligament-an-anatomic-and-mri-investigation
#8
Mandy Hedderwick, Mark D Stringer, Liam McRedmond, Grant R Meikle, Stephanie J Woodley
PURPOSE: Despite being the largest ligament on the posterior aspect of the knee, relatively little is known about the normal morphology of the oblique popliteal ligament (OPL). The aim of this study was to investigate the detailed anatomy of the OPL in cadavers and healthy volunteers. METHODS: The posterior knee was investigated in 25 cadaver lower limbs (mean age 76 ± 9.5 years; 7 men) by dissection, histology, and serial plastination and in 14 healthy individuals (mean age 23 ± 3...
March 21, 2017: Surgical and Radiologic Anatomy: SRA
https://www.readbyqxmd.com/read/28323744/endocytoscopy-for-confirmation-of-surgical-margins-of-peripheral-lung-cancer
#9
Seishi Nosaka, Noriaki Kurimoto, Katsuhiko Morita
No abstract text is available yet for this article.
April 2017: Journal of Bronchology & Interventional Pulmonology
https://www.readbyqxmd.com/read/28323656/tumor-margin-assessment-with-loupe-magnification-enables-greater-histological-clearance-of-facial-basal-cell-carcinomas-compared-with-clinical-examination-alone
#10
Conor M Sugrue, Niall McInerney, Cormac W Joyce, Jack L Kelly
BACKGROUND: Surgical excision of facial basal cell carcinomas (BCCs) is a balance between oncological clearance and conservation of cosmetic and functionally sensitive tissues. OBJECTIVE: To assess if loupe magnification (LM) can enhance the visual assessment of BCC tumor margins resulting in a greater histological clearance. METHODS AND MATERIALS: This prospective study randomized patients with primary facial BCCs into preoperative tumor margin assessment with LM (study group) or clinical examination alone (control group)...
March 17, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28323606/when-and-how-should-clinicians-share-details-from-a-health-record-with-patients-with-mental-illness
#11
Robyn P Thom, Helen M Farrell
Stigma associated with mental illness-a public health crisis-is perpetuated by the language used to describe and document it. Psychiatric pathology and how it can be perceived among clinicians contribute to the marginalization of patients, which exacerbates their vulnerability. Clinical documentation of mental illness has long been mired in pejorative language that perpetuates negative assumptions about those with mental illness. Although patients have the legal right to view their health record, sharing mental health notes with patients remains a sensitive issue, largely due to clinicians' fears that review of this content might cause harm, specifically psychiatric destabilization...
March 1, 2017: AMA Journal of Ethics
https://www.readbyqxmd.com/read/28323579/who-experiences-seclusion-an-examination-of-demographics-and-duration-in-a-public-acute-inpatient-mental-health-service
#12
Jacinta Chavulak, Melissa Petrakis
Restrictive interventions such as seclusion may occur during an acute mental health crisis. Such interventions are experienced by people as traumatic and counter to recovery. The current study aimed to investigate the use of seclusion and who was secluded amongst patients presenting with psychotic symptomology. All acute inpatient admissions were examined across a 12-month period January-December 2013. Electronic and paper records were accessed and audited for all 655 admissions. There were 91 admissions that included a seclusion and 200 seclusion events...
March 21, 2017: Social Work in Health Care
https://www.readbyqxmd.com/read/28323558/reproductive-tract-infections-attitude-and-barriers-among-marginalized-fisher-women-in-kerala-south-india
#13
Manoj A Thomas, Poornima Narayan
Reproductive tract infections (RTIs) are the cause of severe gynecological and maternal morbidity in India. In marginalized communities, women persevere quietly when faced with a culturally sensitive health issue such as an RTI. To hypothesize on the differential health behavior and low levels of reported incidents among women living in marginalized communities, we undertake an exploratory study in a coastal fishermen community in South India. We identify barriers influencing decisions to seek curative and preventive medical care...
April 2017: Health Care for Women International
https://www.readbyqxmd.com/read/28323462/scaling-up-a-water-sanitation-and-hygiene-program-in-rural-bangladesh-the-role-of-program-implementation
#14
Jade Benjamin-Chung, Sonia Sultana, Amal K Halder, Mohammed Ali Ahsan, Benjamin F Arnold, Alan E Hubbard, Leanne Unicomb, Stephen P Luby, John M Colford
OBJECTIVES: To evaluate whether the quality of implementation of a water, sanitation, and hygiene program called SHEWA-B and delivered by UNICEF to 20 million people in rural Bangladesh was associated with health behaviors and sanitation infrastructure access. METHODS: We surveyed 33 027 households targeted by SHEWA-B and 1110 SHEWA-B hygiene promoters in 2011 and 2012. We developed an implementation quality index and compared the probability of health behaviors and sanitation infrastructure access in counterfactual scenarios over the range of implementation quality...
March 21, 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/28323442/an-investigation-of-human-body-model-morphing-for-the-assessment-of-abdomen-responses-to-impact-against-a-population-of-test-subjects
#15
Philippe Beillas, Fabien Berthet
OBJECTIVE: Human Body Models have the potential to better describe the human anatomy and variability than dummies. However, datasets available to verify the human response to impact are typically limited in numbers, and they are not size or gender specific. The objective of the study was to investigate the use of model morphing methodologies within that context. METHODS: In the current study, a simple human model scaling methodology was developed to morph two detailed human models (Global Human Body Model Consortium models 50(th) male, M50 and 5(th) female F05) to the dimensions of Post Mortem Human Surrogates (PMHS) used in published literature...
March 21, 2017: Traffic Injury Prevention
https://www.readbyqxmd.com/read/28320077/marginal-ulcers-after-one-anastomosis-mini-gastric-bypass-a-survey-of-surgeons
#16
K K Mahawar, A N Reed, Y N H Graham
Many surgeons believe that one anastomosis (mini) gastric bypass (OAGB/MGB) is associated with a high marginal ulcer (MU) rate and that this is associated with complications in a significant number of patients. The purpose of this survey was to find out the participant-reported incidence of MU after OAGB/MGB and its complications. We also aimed to understand practices in this cohort concerning prophylaxis, diagnosis, treatment and management of complications. Bariatric surgeons who perform OAGB/MGB procedures were invited to participate in a confidential, online survey using SurveyMonkey®...
March 20, 2017: Clinical Obesity
https://www.readbyqxmd.com/read/28320048/dynamic-effects-of-depressive-symptoms-on-osteoarthritis-knee-pain
#17
Alan M Rathbun, Elizabeth A Stuart, Michelle Shardell, Michelle S Yau, Mona Baumgarten, Marc C Hochberg
OBJECTIVE: To estimate the dynamic causal effects of depressive symptoms on osteoarthritis (OA) knee pain. METHODS: Marginal structural models were used to examine dynamic associations between depressive symptoms and pain over 48 months among older adults (n=2,287) with radiographic knee OA (Kellgren-Lawrence grade=2 or 3) in the Osteoarthritis Initiative. Depressive symptoms at each annual visit were assessed (threshold = ≥ 16) using the Center for Epidemiological Studies Depression Scale...
March 20, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/28320045/local-recurrence-after-laparoscopic-radiofrequency-ablation-of-malignant-liver-tumors-results-of-a-contemporary-series
#18
Hideo Takahashi, Muhammet Akyuz, Erol Aksoy, Koray Karabulut, Eren Berber
INTRODUCTION: The aims of this study were to determine the incidence of Local recurrence (LR) in patients at long-term follow-up after laparoscopic RFA (LRFA) and also to determine the risk factors for LR from a contemporary series. METHODS: Patients undergoing LRFA between 2005 and 2014 by a single surgeon were reviewed. Demographic and perioperative data were analyzed from a prospective database. RESULTS: LRFA was performed on 316 patients with 901 lesions...
March 20, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28319578/podoplanin-and-sox2-expression-in-cin-3-like-squamous-cell-carcinoma-of-the-cervix
#19
Colin J R Stewart, Maxine L Crook
Squamous cell carcinoma (SCC) of the uterine cervix occasionally demonstrates a deceptive growth pattern that mimics endocervical crypt involvement by cervical intraepithelial neoplasia, grade 3 (CIN 3). Such CIN 3-like SCCs may be misinterpreted as noninvasive or minimally invasive leading to delays in diagnosis. Little is known of the factors that influence the growth patterns of cervical SCC but we suggested recently that CIN 3-like tumors might demonstrate "collective cellular invasion," which is characterized by a retained epithelial phenotype...
March 17, 2017: International Journal of Gynecological Pathology
https://www.readbyqxmd.com/read/28319571/hpv-independent-differentiated-vulvar-intraepithelial-neoplasia-dvin-is-associated-with-an-aggressive-clinical-course
#20
Jessica N McAlpine, So Youn Kim, Ardalan Akbari, Sima Eshragh, Miriam Reuschenbach, Magnus von Knebel Doeberitz, Elena S Prigge, Suzanne Jordan, Naveena Singh, Dianne M Miller, C Blake Gilks
Differentiated vulvar intrapeithelial neoplasia (dVIN) is an human papillomavirus (HPV)-independent precursor of squamous cell carcinoma (SCC), and the aim of this study was to better characterize its natural history. Cases of dVIN were identified from the pathology archives. Outcomes of patients with dVIN only, without associated invasive SCC, were compared with a cohort of patients with high-grade squamous intraepithelial lesion [HSIL(VIN3)]. Eighteen patients diagnosed with dVIN with adjacent invasive SCC (SCC/dVIN) and 7 patients with dVIN only, without invasive carcinoma, were identified...
March 17, 2017: International Journal of Gynecological Pathology
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