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https://www.readbyqxmd.com/read/28742784/treatment-and-complications-of-patients-with-ipsilateral-acetabular-and-femur-fractures-a-multicenter-retrospective-analysis
#1
Justin M Hire, Preston J Boyer, Heidi Israel, Lisa K Cannada, Hassan Mir, Jason Halvorson, Gregory J Della Rocca, Bryan Ming, Brian Mullis, Chetan Deshpande
OBJECTIVES: The purpose of this study was to review the treatment of ipsilateral acetabular and femur fracture patients to provide descriptive demographic data, injury pattern classification, treatment and evaluate the complication profile reflective of current practices. STUDY DESIGN: Multicenter retrospective cohort. SETTING: Eight Level 1 Trauma Centers. PATIENTS/PARTICIPANTS: 101 patients met inclusion criteria. INTERVENTION: Surgical treatment of both the acetabular and femur fracture...
July 24, 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28742682/ductal-carcinoma-in-situ-and-margins-2%C3%A2-mm-contemporary-outcomes-with-breast-conservation
#2
Audree B Tadros, Benjamin D Smith, Yu Shen, Heather Lin, Savitri Krishnamurthy, Anthony Lucci, Carlos H Barcenas, Rosa F Hwang, Gaiane Rauch, Lumarie Santiago, Eric A Strom, Sarah M DeSnyder, Wei T Yang, Dalliah M Black, Constance T Albarracin, Mariana Chavez-MacGregor, Kelly K Hunt, Henry M Kuerer
OBJECTIVE: To determine the relationship between negative margin width and locoregional recurrence (LRR) in a contemporary cohort of ductal carcinoma in situ (DCIS) patients. BACKGROUND: Recent national consensus guidelines recommend an optimal margin width of 2 mm or greater for the management of DCIS; however, controversy regarding re-excision remains when managing negative margins <2 mm. METHODS: One thousand four hundred ninety-one patients with DCIS who underwent breast-conserving surgery from 1996 to 2010 were identified from a prospectively managed cancer center database and analyzed using univariate and multivariate Cox proportional hazard models to determine the relationship between negative margin width and LRR with or without adjuvant radiation therapy (RT)...
July 24, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28742647/the-dis-utility-of-a-change-in-troponin-i-for-diagnosis-of-non-st-segment-elevation-myocardial-infarction-in-an-observation-unit
#3
Iani Patsias, Benjamin Swanson, Michael Hudson, Sachin Parikh, Khaled Nour, Gordon Jacobsen, James McCord
BACKGROUND: Observation units (OUs) may be an efficient and effective setting to diagnose and risk stratify patients with coronary ischemia and myocardial infarction (MI). Given improved cardiac troponin I (cTnI) assays and expanded utilization of OUs, it is not uncommon for patients with mildly elevated cTnI to be evaluated in OUs. We investigated the serial cTnI results in OU patients to determine whether absolute or relative cTnI changes were useful for the diagnosis of MI. METHODS: This was a retrospective study of 260 patients placed in the OU from a single center in 2007, with an initial cTnI in the indeterminate range of 0...
September 2017: Critical Pathways in Cardiology
https://www.readbyqxmd.com/read/28742563/identity-capital-and-identifying-learners-at-risk-for-marginalization
#4
Timothy Gordon Dyster
No abstract text is available yet for this article.
August 2017: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/28742544/the-marginal-costs-of-adverse-drug-events-associated-with-exposures-to-anticoagulants-and-hypoglycemic-agents-during-hospitalization
#5
William D Spector, Rhona Limcangco, Michael F Furukawa, William E Encinosa
BACKGROUND: Anticoagulants and hypoglycemic agents are 2 of the most challenging drug classes for medical management in the hospital resulting in many adverse drug events (ADE). OBJECTIVE: Estimating the marginal cost (MC) of ADEs associated with anticoagulants and hypoglycemic agents for adults in 5 patient groups during their hospital stay and the total annual ADE costs for all patients exposed to these drugs during their stay. RESEARCH DESIGN AND SUBJECT: Data are from 2010 to 2013 Healthcare Cost and Utilization Project (HCUP) State Inpatient Databases and Medicare Patient Safety Monitoring System (MPSMS)...
July 24, 2017: Medical Care
https://www.readbyqxmd.com/read/28742441/principles-of-care-for-women-experiencing-intimate-partner-violence-views-of-expert-japanese-health-professionals-and-advocates
#6
Maki Umeda, Yaeko Kataoka, Elizabeth Miller
In Japan, interventions for Intimate Partner Violence (IPV) in the health care setting are rare, partly due to Japanese cultural norms that marginalize women's IPV experiences. A thematic analysis of narratives of eight Japanese health professionals who are experts in IPV care identified shared core values and practices that have guided their development of culturally relevant IPV interventions: supporting women's autonomy to define what is at stake for her, appreciating unique trajectories and timing for recovery, and practicing shared decision making...
July 25, 2017: Health Care for Women International
https://www.readbyqxmd.com/read/28742384/antiproliferative-effects-of-red-and-white-wine-extracts-in-pc-3-prostate-cancer-cells
#7
Roxane Tenta, Elizabeth Fragopoulou, Magafoula Tsoukala, Marianna Xanthopoulou, Maria Skyrianou, Harris Pratsinis, Dimitris Kletsas
Experimental and epidemiological studies have shown that antioxidant polyphenols can act as chemopreventive agents against prostate cancer. Cabernet Sauvignon and Rombola wine were extracted in order to obtain fractions containing different classes of compounds. All extracts inhibited the androgen-insensitive human prostate cancer cells (PC-3) proliferation in a dose-dependent manner. The most potent compounds were selected to be further tested.Treatment of PC-3 cells with the selected wine extracts marginally increased the cell distribution in S phase, while producing a remarkable induction of autophagy...
July 25, 2017: Nutrition and Cancer
https://www.readbyqxmd.com/read/28742369/effect-of-curcumin-addition-on-the-adsorption-and-transport-of-a-cationic-dye-across-dppg-popg-liposomes-probed-by-second-harmonic-spectroscopy
#8
Gopal K Varshney, Srinivas R Kintali, Kaustuv Das
The effect of addition of Curcumin on the adsorption and transport characteristics of a cationic dye, (LDS+), across negatively charged bilayers composed of POPG and DPPG lipids were investigated by the interface selective Second Harmonic (SH) spectroscopic technique. Curcumin induced changes in the SH electric field signal of the LDS+ ions (E2ω (LDS+)) were observed to depend critically on the bilayer acyl chain saturation/un-saturation ratio (S/U). Following earlier works, the increase in the E2ω (LDS+) signal is attributed to the release of the Na+ counter-ions present in the head-group region of the bilayer by Curcumin and the decay of the E2ω (LDS+) signal is attributed to the bilayer intercalated state of Curcumin...
July 25, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28742164/relationship-between-implant-stability-on-the-abutment-and-platform-level-by-means-of-resonance-frequency-analysis-a-cross-sectional-study
#9
Frederico Santos Lages, Dhelfeson Willya Douglas-de-Oliveira, Guilherme Siqueira Ibelli, Fatimah Assaf, Thallita Pereira Queiroz, Fernando Oliveira Costa
Resonance frequency analysis (RFA) has become the main tool used to assess the osseointegration of dental implants. The objective of this study was to verify the relationship between the ISQ values with different prosthetic abutments and with the implant platform. The hypothesis was that ISQ values changes according to the abutment height. Twelve patients were included, whose contribution to the study was 31 dental implants (external hexagon connection implants, 4.1x10 mm). The temporary implant-supported crown and prosthetic components were removed and the following smartpegs were inserted, one at a time: type 1, in the implant platform (G1); type A3, in the microunit component with 1mm transmucosal height (G2) and type A3, in the microunit component with 5mm transmucosal height (G3)...
2017: PloS One
https://www.readbyqxmd.com/read/28741600/coverage-based-constraints-for-imrt-optimization
#10
Henning Mescher, Silke Ulrich, Mark Bangert
Radiation therapy treatment planning requires an incorporation of uncertainties in order to guarantee an adequate irradiation of the tumor volumes. In current clinical practice, uncertainties are accounted for implicitly with an expansion of the target volume according to generic margin recipes. Alternatively, it is possible to account for uncertainties by explicit minimization of objectives that describe worst case treatment scenarios, the expectation value of the treatment, or the coverage probability of the target volumes during treatment planning...
July 25, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28741576/a-randomized-comparison-of-biodegradable-polymer-and-permanent-polymer-coated-platinum-chromium-everolimus-elutingcoronary-stents-in-china-the-evolve-china-study
#11
YaLing Han, Haiwei Liu, Yuejin Yang, Jian Zhang, Kai Xu, Guosheng Fu, Xi Su, Tiemin Jiang, Wenyue Pang, Jiyan Chen, Zuyi Yuan, Hui Li, Haichang Wang, Tao Hong, Huiliang Liu, Fucheng Sun, Dominic J Allocco, Mingdong Zhang, Keith D Dawkins
AIMS: The EVOLVE China randomized study sought to evaluate clinical safety and effectiveness of the SYNERGY bioabsorbable polymer-coated everolimus-eluting stent (EES) for the treatment of patients with coronary heart disease in China. METHODS AND RESULTS: Eligible patients with de novo native coronary artery lesions were randomized (1:1) to receive the SYNERGY or PROMUS Element Plus (PE Plus) stents. The primary endpoint was in-stent late loss at 9 months. Secondary endpoints included death, MI, revascularization, and stent thrombosis through 12 months...
July 25, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28741420/outreach-syncope-clinic-managed-by-a-nurse-practitioner-outcome-and-cost-effectiveness
#12
Mohamed H Hamdan, Kathleen E Walsh, Michele Brignole, Jamie Key
Introduction The purpose of this study was to assess the clinical and financial outcomes of a novel outreach syncope clinic. Methods We compared the clinical outcome of the Faint and Fall Clinic at the American Center (January-June 2016) with that of the University of Wisconsin Health and Clinics Faint and Fall Clinic (January 2013-December 2014). The American Center-Faint and Fall Clinic is run solely by a nurse practitioner, assisted by online faint-decision software and consultancy of a faint specialist through video-conferencing...
January 1, 2017: Journal of Telemedicine and Telecare
https://www.readbyqxmd.com/read/28741376/rate-of-symptomatic-lymphocele-formation-after-extraperitoneal-vs-transperitoneal-robot-assisted-radical-prostatectomy-and-bilateral-pelvic-lymphadenectomy
#13
David Horovitz, Xiang Lu, Changyong Feng, Edward M Messing, Jean Volny Joseph
INTRODUCTION AND OBJECTIVE: With the peritoneum acting as a natural surface for lymphatic reabsorption, transperitoneal robot-assisted radical prostatectomy (tRARP) is thought to be associated with a lower incidence of symptomatic lymphocele (SL) compared to its extraperitoneal counterpart (eRARP) when bilateral pelvic lymph node dissection (BPLND) is performed. Herein, we aim to determine if there is a difference in SL formation and characteristics between the two approaches. METHODS: We reviewed the records of patients who underwent eRARP or tRARP and BPLND at a tertiary care academic center from July 1, 2003 to May 31, 2016...
July 25, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/28741335/cardiopulmonary-bypass-time-every-minute-counts
#14
Sudharsan Madhavan, Siew-Pang Chan, Wei-Chuan Tan, Jolane Eng, Bowen Li, Hai-Dong Luo, Leok-Kheng K Teoh
BACKGROUND: This study was conducted to examine the impact of CPB times on post-operative outcomes. We sought to determine the optimum cut-offs of CPB per graft time and cumulative CPB time and their predictive accuracy for mortality in conjunction with EuroSCORE II. METHODS: The de-identified data of 1,960 patients who had undergone isolated on-pump CABG from 2009 to 2014 were analyzed. The risk strata of CPB/graft and cumulative CPB times, identified with a decision tree, were added into an augmented model for predicting short- and intermediate-term post-operative clinical events...
July 24, 2017: Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/28741332/willingness-to-use-hiv-pre-exposure-prophylaxis-among-gay-men-other-men-who-have-sex-with-men-and-transgender-women-in-myanmar
#15
Bridget L Draper, Zaw Min Oo, Zaw Win Thein, Poe Poe Aung, Vanessa Veronese, Claire Ryan, Myo Thant, Chad Hughes, Mark Stoové
INTRODUCTION: HIV pre-exposure prophylaxis (PrEP) has emerged as a key component of contemporary HIV combination prevention strategies. To explore the local suitability of PrEP, country-specific acceptability studies are needed to inform potential PrEP implementation. In the context of Myanmar, in addition to resource constraints, HIV service access by gay men, other men who have sex with men, and transgender women (GMT) continues to be constrained by legislative and community stigma and marginalization...
July 26, 2017: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/28741325/continuous-pain-and-swelling-after-humerus-fracture-in-an-86-years-old-woman
#16
M Herrera-Pérez, J Boluda-Mengod, R Muñoz-Ortus, M J Gutiérrez-Morales, J Pais-Brito
Metastases to bone are the most frequent cause of destructive lesions to the skeleton in adults . The tumours that are most likely to metastasize to bone are prostate (32%), breast (22%), kidney (16%), lung and thyroid. The typical distribution of metastatic lesions are to the spine, ribs, pelvis, and proximal limb girdles. The humerus is the second most common site for long bone metastases, behind only the femur in its frequency of involvement . It represents the 20% of all bony metastases. We present a clinical case of an 86 yo woman with a previous diagnosis of myofibroblastic sarcoma of the maxillaris who suffers a pathological fracture of the humeral shaft secondary to metastasis and was misdiagnosed and treated for a typical humeral fracture using and intramedullary pinning (Hackethal technique), producing the progression of the disease within the humeral shaft...
January 2017: Acta Ortopédica Mexicana
https://www.readbyqxmd.com/read/28741172/glass-ionomer-cement-inhibits-secondary-caries-in-an-in-vitro-biofilm-model
#17
Norbert Krämer, Miriam Schmidt, Susanne Lücker, Eugen Domann, Roland Frankenberger
OBJECTIVES: The objective of this study was to investigate the effect of different glass ionomer cements on secondary caries inhibition in a fully automated in vitro biofilm model. MATERIALS AND METHODS: One hundred and twenty-four extracted third molars received class V cavities and were filled with one conventional (Ketac Molar/KM), and two resin-modified glass ionomer cements (Photac Fil/PF, Ketac N100/KN, 3M Espe). A bonded resin composite (Single Bond Plus/Filtek Supreme XTE) served as control...
July 24, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28741123/neoadjuvant-radiotherapy-is-associated-with-r0-resection-and-improved-survival-for-patients-with-extremity-soft-tissue-sarcoma-undergoing-surgery-a-national-cancer-database-analysis
#18
Alicia A Gingrich, Sarah B Bateni, Arta M Monjazeb, Morgan A Darrow, Steven W Thorpe, Amanda R Kirane, Richard J Bold, Robert J Canter
BACKGROUND: Neoadjuvant radiotherapy (RT) is increasingly advocated for the management of soft tissue sarcoma (STS). Therefore, this study sought to characterize the impact of neoadjuvant RT on rates of R0 resection and overall survival (OS) in extremity STS patients undergoing surgery. METHODS: From January 2003 to December 2012, the study identified patients with a diagnosis of extremity STS from the National Cancer Database. After exclusion of patients younger than 18 years, not treated by surgery, who had metastases at diagnosis, intraoperative RT, and missing or unknown data, 27,969 patients were identified...
July 24, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/28741053/prediction-of-outcome-in-pediatric-hodgkin-lymphoma-based-on-interpretation-of-18-fdg-pet-ct-according-to-%C3%AE-suvmax-deauville-5-point-scale-and-ihp-criteria
#19
Emine Göknur Isik, Serkan Kuyumcu, Rejin Kebudi, Yasemin Sanli, Zeynep Karakas, Fatma Betul Cakir, Seher Nilgün Unal
OBJECTIVE: Minimizing side effects by using response-adopted therapy strategies plays an important role in the management of pediatric Hodgkin lymphoma (HL); however, the criteria for the definition of adequate or inadequate response are controversial. The aim of this study is to compare different methods of interpretation of (18)F-FDG-PET/CT (PET) in the prediction of disease outcome in order to determine the optimum method in this regard. METHODS: Baseline, interim and post-treatment PET scans of 72 children were interpreted according to revised International Harmonization Project criteria (IHP) and Deauville criteria...
July 24, 2017: Annals of Nuclear Medicine
https://www.readbyqxmd.com/read/28740972/in-vivo-microbiologic-evaluation-of-polytetrafluoroethylene-and-cotton-as-endodontic-spacer-materials
#20
Tina Olsson, Daniel Chan, James D Johnson, Avina Paranjpe
OBJECTIVE: Spacers are commonly placed between the canal orifice and the temporary material between endodontic treatment appointments. This prevents the temporary restoration material from obstructing the canal orifices and allows for easy removal. Various endodontic spacers are currently used, including polytetrafluoroethylene (PTFE) tape. Previous in-vitro studies have demonstrated the advantages of using PTFE over using cotton; however, no in-vivo studies have demonstrated this. Hence, the purpose of this study was to evaluate which spacer showed less bacterial leakage between endodontic treatments...
July 20, 2017: Quintessence International
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