keyword
MENU ▼
Read by QxMD icon Read
search

Sinonasal

keyword
https://www.readbyqxmd.com/read/29327734/clinical-study-of-extrapulmonary-head-and-neck-tuberculosis-in-an-urban-setting
#1
S Monga, J N Malik, S Jan, S Bahadur, S Jetley, H Kaur
Tuberculosis (TB) of the head and neck region is quite common in endemic countries, but is still misdiagnosed due to its varied presentation and different sites of involvement. The aims of the present study were to present the diversities of presentation of head and neck tuberculosis with the diagnostic predicaments faced during evaluation and to assess treatment response to anti-tubercular treatment (ATT). We analysed 48 patients with head and neck tuberculosis who presented to the Department of Otorhinolaryngology in our tertiary care urban hospital over a period of two years from 2013 to 2015 and recorded their data, which included presenting complaints, local and systemic examination findings, investigation results and treatment outcomes...
December 2017: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/29327137/microrna-expression-in-smarcb1-ini1-deficient-sinonasal-carcinoma-a-clinicopathological-and-molecular-genetic-study
#2
Jan Laco, Helena Kovaříková, Marcela Chmelařová, Hana Vošmiková, Kateřina Sieglová, Ivana Baranová, Pavel Dundr, Kristýna Němejcová, Jaroslav Michálek, Jana Šatanková, Milan Vošmik, Aleš Ryška
No abstract text is available yet for this article.
January 11, 2018: Virchows Archiv: An International Journal of Pathology
https://www.readbyqxmd.com/read/29323796/treatment-of-chronic-rhinosinusitis-with-dornase-alfa-in-patients-with-cystic-fibrosis-a-systematic-review
#3
Gopi B Shah, Linde De Keyzer, Joy A Russell, Ashleigh Halderman
BACKGROUND: A major component of sputum in cystic fibrosis (CF) patients is polymerized DNA, a byproduct of degraded neutrophils. Dornase alfa (dornase) selectively cleaves extracellular DNA and reduces the viscosity of sputum. It improves mucociliary clearance and pulmonary function. The benefit of dornase on CF-associated sinusitis is less clear. Therefore, the objective of this study was to systematically review the use of dornase on chronic rhinosinusitis (CRS) in CF patients. METHODS: The Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement was followed for this systematic review...
January 11, 2018: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/29322795/analysis-of-dna-methylation-and-microrna-expression-in-nut-nuclear-protein-in-testis-midline-carcinoma-of-the-sinonasal-tract-a-clinicopathological-immunohistochemical-and-molecular-genetic-study
#4
J Laco, H Kovarikova, M Chmelarova, H Vosmikova, K Sieglova, I Bubancova, P Dundr, K Nemejcova, J Michalek, P Celakovsky, R Mottl, I Sirak, M Vosmik, I Marek, T Geryk, J Mejzlik, J Satankova, A Ryska
The aim of this study was a detailed clinicopathological investigation of sinonasal NUT midline carcinoma (NMC), including analysis of DNA methylation and microRNA (miRNA) expression. Three (5%) cases of NMC were detected among 56 sinonasal carcinomas using immunohistochemical screening and confirmed by fluorescence in situ hybridization. The series comprised 2 males and 1 female, aged 46, 60, and 65 years. Two tumors arose in the nasal cavity and one in the maxillary sinus. The neoplasms were staged pT1, pT3, and pT4a (all cN0M0)...
2018: Neoplasma
https://www.readbyqxmd.com/read/29319936/submucosal-gland-mucus-strand-velocity-is-decreased-in-chronic-rhinosinusitis
#5
Kiranya E Tipirneni, Shaoyan Zhang, Do-Yeon Cho, Jessica Grayson, Daniel F Skinner, Calvin Mackey, Lindsay Moore, Denzel Cole, Catherine G Banks, Bradford A Woodworth
BACKGROUND: Chronic rhinosinusitis (CRS) may be initiated by innately impaired host defense mechanisms that predispose the upper airways to infection. Recent evidence suggests tethering of submucosal gland mucus strands represents an inciting event within cystic fibrosis (CF) airways, occurring prior to onset of chronic infection. Submucosal gland hypertrophy and defective mucociliary clearance (MCC) are present in actively inflamed sinuses, but mucus strand velocity may also be affected as a secondary event, further contributing to chronic disease...
January 10, 2018: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/29319887/depressed-mood-is-associated-with-loss-of-productivity-in-allergic-rhinitis
#6
Adam P Campbell, Lloyd P Hoehle, Katie M Phillips, David S Caradonna, Stacey T Gray, Ahmad R Sedaghat
Allergic rhinitis (AR) is associated with significant decreases in quality of life and productivity losses. We hypothesized that symptoms of AR may differentially associate with lost productivity due to AR. We performed a cross-sectional cohort study of 105 prospectively recruited patients with persistent AR. AR control, severity of depressed mood and sinonasal symptoms were assessed with the Rhinitis Control Assessment Test (RCAT), Patient Health Questionnaire (PHQ-2), and the 22-item Sinonasal Outcome Test (SNOT-22) respectively...
January 10, 2018: Allergy
https://www.readbyqxmd.com/read/29314082/case-report-hpv-related-carcinoma-with-adenoid-cystic-like-features-of-the-sinonasal-tract
#7
Robert J Chouake, Molly Cohen, Alfred-Marc Iloreta
Human papillomavirus-related carcinoma with adenoid cystic-like features is a newly described histologic variant of sinonasal tract carcinoma. The implications of this sinonasal malignancy is still being evaluated. There are a limited number of cases reported in the literature, and thus we seek to further characterize this patient population and review the histologic features of this malignancy with the following two cases. The behavior of this entity is as yet uncertain. Laryngoscope, 2018.
January 4, 2018: Laryngoscope
https://www.readbyqxmd.com/read/29302898/systemic-non-hodgkin-t-cell-lymphomas-presenting-in-the-head-and-neck-region-an-institutional-experience-of-a-rare-entity
#8
Devin R Broadwater, Deniz Peker
T cell lymphoma (TCL) is a group of rare and aggressive diseases. TCL primary to head and neck organs often present as extranodal NK/T cell lymphoma, nasal type. Systemic TCL with initial head and neck presentation is extremely rare. Here we report our institutional experience. Clinicopathologic data was collected from patients diagnosed with TCL and treated at the University of Alabama at Birmingham between 2002 and 2012. Eleven cases of systemic TCL initially presented at head and neck region were identified...
January 4, 2018: Head and Neck Pathology
https://www.readbyqxmd.com/read/29301179/glomangiopericytoma-of-the-spinal-cord
#9
Sung Shik Kang, Hee Seok Jeong, Hee Young Son, Tae Yong Moon
Glomangiopericytoma, also referred to as a hemangiopericytoma-like tumor or sinonasal type hemangiopericytoma, is a rare tumor of the nasal cavity and paranasal sinus that has never been reported in the spinal cord. Here, we report a case of a 47-year-old man who developed glomangiopericytoma in the thoracic spine. This lesion showed a heterogeneous high signal intensity compared to the spinal cord on a T2-weighted image and an easily enhanced isointense signal on a T1-weighted image.
December 2017: Korean Journal of Spine
https://www.readbyqxmd.com/read/29288039/immunoglobulin-g4-related-chronic-rhinosinusitis-a-pitfall-in-the-differential-diagnosis-of-granulomatosis-with-polyangiitis-rosai-dorfman-disease-and-fungal-rhinosinusitis
#10
Yingshi Piao, Yuan Zhang, Changli Yue, Chengshuo Wang, Luo Zhang
Immunoglobulin G4 (IgG4)-related chronic rhinosinusitis (CRS) has recently been proposed to be a new clinical entity of nasal disease, with no consensually agreed criteria for diagnosis. Moreover, the pathological features if IgG4-related CRS often overlap with other sinonasal inflammatory and autoimmune diseases such as Granulomatosis with Polyangiitis (GPA), Rosai-Dorfman disease (RDD) and Fungal Rhinosinusitis (FRS). We aimed to explore the specific similarities and differences in clinicopathologic features between IgG4-related CRS, and GPA, RDD and FRS, in order that these conditions can be diagnosed more accurately...
December 26, 2017: Human Pathology
https://www.readbyqxmd.com/read/29286998/endoscopic-repairs-of-sinonasal-cerebrospinal-leaks-outcome-and-prognostic-factors
#11
Xiaole Song, Dehui Wang, Xicai Sun, Quan Liu, Li Hu, Yurong Gu, Huankang Zhang
OBJECTIVE: The aim of this study was to review the management of sinonasal cerebrospinal fluid (CSF) leaks and outcome of endoscopic repairs and to provide experience regarding leaks at the lateral wall of sphenoid sinus and the posterior wall of frontal sinus. METHODS: Patients who underwent endoscopic repairs of CSF leaks were reviewed. Characteristics of different etiologies were compared, and prognostic factors were analyzed. RESULTS: The study included 144 patients with 150 CSF leaks, in which spontaneous leaks account for 55%...
January 2018: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29283946/rhinogenic-contact-point-headache-surgical-treatment-versus-medical-treatment
#12
Ignazio La Mantia, Calogero Grillo, Claudio Andaloro
Rhinogenic contact point headache (RCPH) is a headache syndrome secondary to mucosal contact points in the sinonasal cavities, in the absence of inflammatory signs, hyperplastic mucosa, purulent discharge, sinonasal polyps, or masses. It may result from pressure on the nasal mucosa due to anatomic variations among which the septal deviation, septal spur, and concha bullosa, are the most commonly observed. In recent years, RCPH has remained a subject of controversy regarding both its pathogenesis and treatment...
December 27, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29283936/a-patient-with-submerged-sinonasal-angiosarcoma-after-resection-of-underlying-organizing-hematoma
#13
Hyo Jin Chung, Myoung Ju Koh, Chang-Hoon Kim, Jung Hyun Chang
A 30-year-old female patient with facial pain diagnosed as organizing hematoma of maxillary sinus by biopsy and imaging studies, and subsequently tumor was resected via an endoscope-assisted midfacial degloving approach. The tumor was histopathologically confirmed as organizing hematoma. In 3-week follow-up, asymptomatic emerging mass was observed at the same site, and needed a revision endoscopic resection. On pathologic examination, a low-grade angiosarcoma was identified, not organizing hematoma. After postoperative radiotherapy, she has been a status of no evidence of disease...
December 27, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29282671/sinonasal-tract-solitary-fibrous-tumor-a-clinicopathologic-study-of-six-cases-with-a-comprehensive-review-of-the-literature
#14
Lester D R Thompson, Sean K Lau
Solitary fibrous tumors (SFTs) are well recognized in the head and neck region, but rarely arise in the sinonasal tract (SNT). Six primary SNT SFTs were identified in the files of Southern California Permanente Medical Group between 2006 and 2017. The patients included five males and one female ranging in age from 33 to 72 years (mean 52 years), most of whom presented clinically with nasal obstruction. Three tumors involved the nasal cavity alone, one involved the paranasal sinuses, and two involved both the nasal cavity and paranasal sinuses...
December 27, 2017: Head and Neck Pathology
https://www.readbyqxmd.com/read/29280680/smarcb1-deficient-tumors-of-childhood-a-practical-guide
#15
Bruce R Pawel
The SMARCB1 gene ( INI1, BAF47) is a member of the SWItch/Sucrose Non-Fermentable (SWI/SNF) chromatin remodeling complex, involved in the epigenetic regulation of gene transcription. SMARCB1 acts as a tumor suppressor gene, and loss of function of both alleles gives rise to SMARCB1-deficient tumors. The prototypical SMARCB1-deficient tumor is the malignant rhabdoid tumor (MRT) which was first described in the kidney but also occurs in soft tissue, viscera, and the brain (where it is referred to as atypical teratoid rhabdoid tumor or AT/RT)...
January 1, 2017: Pediatric and Developmental Pathology
https://www.readbyqxmd.com/read/29280026/management-of-non-functioning-pituitary-adenomas-surgery
#16
REVIEW
David L Penn, William T Burke, Edward R Laws
Non-functional pituitary adenomas (NFPAs) are benign tumors of the pituitary gland that do not over-secrete hormonal products, therefore, they are generally detected through symptoms of mass effect, including headache, vision loss, or hypopituitarism. There are multiple pathological subtypes of NFPAs, such as null cell adenomas, silent gonadotrophs, silent somatotrophs, silent corticotrophs, and silent subtype 3, all of which can be classified based on immunohistochemical studies and electron microscopy. Despite these numerous pathological subtypes, surgical resection remains the first-line treatment for NFPAs...
December 26, 2017: Pituitary
https://www.readbyqxmd.com/read/29279173/differentiating-between-benign-and-malignant-sinonasal-lesions-using-dynamic-contrast-enhanced-mri-and-intravoxel-incoherent-motion
#17
Jingxuan Jiang, Zebin Xiao, Zuohua Tang, Yufeng Zhong, Jinwei Qiang
PURPOSE: To explore the value of dynamic contrast-enhanced MRI (DCE-MRI) and intravoxel incoherent motion (IVIM) for distinguishing between benign and malignant sinonasal lesions and investigate the correlations between the two methods. METHODS AND MATERIALS: Patients with sinonasal lesions (42 benign and 31 malignant) who underwent DCE-MRI and IVIM before confirmation by histopathology were enrolled in this prospective study. Parameters derived from DCE-MRI and IVIM were measured, the optimal cut-off values for differential diagnosis were determined, and the correlations between the two methods were evaluated...
January 2018: European Journal of Radiology
https://www.readbyqxmd.com/read/29278464/the-sinonasal-microbiota-neural-signaling-and-depression-in-chronic-rhinosinusitis
#18
Michael Hoggard, Angela Nocera, Kristi Biswas, Michael W Taylor, Richard G Douglas, Benjamin S Bleier
BACKGROUND: The complex relationships between the human microbiota, the immune system, and the brain play important roles in both health and disease, and have been of increasing interest in the study of chronic inflammatory mucosal conditions. We hypothesized that the sinonasal microbiota may act as a modifier of interkingdom neural signaling and, subsequently, mental health, in the upper respiratory inflammatory condition chronic rhinosinusitis (CRS). In this study we investigated associations between the sinonasal microbiota; local concentrations of the neurotransmitters serotonin, dopamine, and γ-aminobutyric acid (GABA); and depression severity in a cohort of 14 CRS patients and 12 healthy controls...
December 26, 2017: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/29277853/endoscopic-endonasal-resection-of-sinonasal-anterior-skull-base-malignancy-kadish-c-esthesioneuroblastoma
#19
Gautam U Mehta, Ehab Y Hanna, Franco DeMonte, Shaan M Raza
BACKGROUND: The surgical management of anterior skull base malignancies requires the full complement of open and endoscopic skull base approaches. Due to the evolution of endoscopic techniques, endoscopic approaches are now being employed for complex skull base tumors. METHODS: We present our technique for endoscopic management for an advanced (T4) anterior skull base malignancy that provides a systematic approach to resection, margin assessment, and reconstruction...
December 26, 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/29274415/the-activation-and-function-of-il-36%C3%AE-in-neutrophilic-inflammation-in-chronic-rhinosinusitis
#20
Hai Wang, Zhi-Yong Li, Wen-Xiu Jiang, Bo Liao, Guan-Ting Zhai, Nan Wang, Zhen Zhen, Jian-Wen Ruan, Xiao-Bo Long, Heng Wang, Wei-Hong Liu, Geng-Tian Liang, Wei-Min Xu, Atsushi Kato, Zheng Liu
BACKGROUND: Although increased accumulation of neutrophils has been noted in chronic rhinosinusitis (CRS), the function and regulation of neutrophils in CRS are largely unknown. IL-36 family cytokines may play an important role in neutrophilic inflammation. OBJECTIVE: To investigate the expression and function of IL-36 cytokines in CRS. METHODS: Quantitative RT-PCR, immunohistochemistry, immunofluorescence, and ELISA were used to investigate the expression of IL-36 cytokines and IL-36 receptor (IL-36R) in sinonasal mucosa...
December 20, 2017: Journal of Allergy and Clinical Immunology
keyword
keyword
83861
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"