Klaudia Stangel-Wójcikiewicz, Maciej Murawski, Tomasz Schwarz, Krzysztof Skotniczny, Agnieszka Fuchs, Jan Wolski, Julia Radwan-Pragłowska, Łukasz Janus, Marek Piątkowski, Marta Kot, Andrzej Wróbel, Dorota Wojtysiak, Przemysław Urbaniec
This prospective study aimed to assess the feasibility of chitosan biomaterial and subcutaneous gel implantation in an ovine model, with implications for women with genital prolapse. Twenty-four ewes were divided into four groups (n = 6 per group): chitosan type B, chitosan type C, chitosan unmodified injections, and polypropylene mesh. Ovine models were chosen due to their morphological resemblance to human reproductive organs. Animals were sacrificed after 90 days for macroscopic, pathomorphological, and immunohistochemical analysis...
March 28, 2024: International Journal of Molecular Sciences