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https://www.readbyqxmd.com/read/29227911/inhibin-a-and-inhibin-b-in-cyclic-and-pregnant-mares-and-mares-with-granulosa-theca-cell-tumors-physiological-and-diagnostic-implications
#1
A J Conley, E L Scholtz, G Dujovne, R F Cotterman, E L Legacki, R C Uliani, M A Alvarenga, B A Ball, B Kalra, G V Savjani, A Kumar
Studies in mares have examined serum inhibin concentrations using immuno-assays unable to distinguish dimeric inhibin-A from inhibin-B isoforms. Inhibin-A and inhibin-B immuno-assays were used to investigate concentrations in cyclic mares, young and old (6 vs 19 years old, respectively) mares following hemi-ovariectomy, mares during pregnancy and in mares with confirmed granulosa cell tumors (GCTs). Mares with inter-ovulatory intervals of 26 days had ovulatory peaks of inhibin-A averaging 80 pg/mL with a mid-cycle nadir of 5 pg/mL...
December 7, 2017: Theriogenology
https://www.readbyqxmd.com/read/29224858/a-resynchronization-of-ovulation-program-based-on-ovarian-structures-present-at-nonpregnancy-diagnosis-reduced-time-to-pregnancy-in-lactating-dairy-cows
#2
R Wijma, M M Pérez, M Masello, M L Stangaferro, J O Giordano
Our objective was to evaluate time to pregnancy after the first service postpartum and pregnancy per artificial insemination (P/AI) in dairy cows managed with 2 resynchronization of ovulation programs. After first service, lactating Holstein cows were blocked by parity (primiparous vs. multiparous) and randomly assigned to the d 32 Resynch (R32; n = 1,010) or short Resynch (SR; n = 1,000) treatments. Nonpregnancy diagnosis (NPD) was conducted 32 ± 3 d after AI by transrectal ultrasonography. Nonpregnant cows in R32 received the Ovsynch protocol: GnRH, PGF2α 7 d later, GnRH 56 h later, and timed AI (TAI) 16 to 18 h later...
December 7, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/29223749/egg-freezing-for-age-related-fertility-decline
#3
Julio Saumet, Angel Petropanagos, Karen Buzaglo, Eileen McMahon, Gunwant Warraich, Neal Mahutte
OBJECTIVE: To provide a comprehensive review and evidence based recommendations for Canadian fertility centres that offer social egg freezing. OUTCOMES: In social egg freezing cycles we evaluated thawed oocyte survival rates, fertilization rates, embryo quality, pregnancy rates, and live birth rates. We also review how these outcomes are impacted by age, ovarian reserve, and the number of eggs cryopreserved. Finally, we discuss the risks of social egg freezing, the alternatives, the critical elements for counselling and informed consent, and future reporting of egg freezing outcome data...
December 6, 2017: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/29221424/effects-of-dehydroepiandrosterone-supplementation-on-mice-with-diminished-ovarian-reserve
#4
Xiufeng Lin, Jing Du, Yan Du, Riran Wu, Xiaowu Fang, Yuechan Liao, Song Quan
Dehydroepiandrosterone (DHEA) has been used to improve the pregnancy rate in women with diminished ovarian reserve(DOR) during in vitro fertilization. We aimed to validate the effects of DHEA and identify the possible mechanisms. We constructed a mice model with DOR and analyzed the hormone parameters and follicle counts. In vivo experiment, FSH and LH concentrations in the serum were significantly elevated in the DOR group. However, the FSH and LH concentrations were partially reversed in the DOR + DHEA group...
December 8, 2017: Gynecological Endocrinology
https://www.readbyqxmd.com/read/29220203/recent-advances-in-fertility-preservation-and-counseling-for-female-cancer-patients
#5
Marie-Madeleine Dolmans
Ensuring quality of life for increasing numbers of women surviving cancer has become a key challenge. Patients need to be counseled on potential fertility loss resulting from gonadotoxic treatments, and referred to fertility specialists to discuss existing options and available results. Areas covered: Fertility preservation options have existed for over twenty years. The proposed fertility preservation approach depends on patient age, the urgency of required chemotherapy, and psychosocial factors such as financial concerns, especially in countries where techniques are not covered by social security...
December 8, 2017: Expert Review of Anticancer Therapy
https://www.readbyqxmd.com/read/29218679/possibility-of-women-treated-with-fertility-sparing-surgery-for-non-epithelial-ovarian-tumors-to-safely-and-successfully-become-pregnant-a-chinese-retrospective-cohort-study-among-148-cases
#6
Bin Yang, Yan Yu, Jing Chen, Yan Zhang, Ye Yin, Nan Yu, Ge Chen, Shifei Zhu, Haiyan Huang, Yongqun Yuan, Jihui Ai, Xinyu Wang, Kezhen Li
This study was performed to evaluate the oncological and reproductive outcomes of childbearing-age women treated with fertility-sparing surgery (FSS) for non-epithelial ovarian tumors in China. One hundred and forty eight non-epithelial ovarian tumor women treated with FSS between January 1, 2000 and August 31, 2015 from two medical centers in China were identified. Progression-free survival (PFS) was 88.5%, whereas overall survival (OS) was 93.9%. Univariate analysis suggested that delivery after treatment is related to PFS (P = 0...
December 7, 2017: Frontiers of Medicine
https://www.readbyqxmd.com/read/29214348/effect-of-laser-assisted-zona-thinning-during-assisted-reproduction-on-pregnancy-outcome-in-women-with-endometriosis-randomized-controlled-trial
#7
Adel Mohamed Nada, Amr El-Noury, Hesham Al-Inany, Mamdouh Bibars, Tamer Taha, Sameh Salama, Fatma Hassan, Eman Zein
OBJECTIVE: To compare the ICSI-ET outcomes in patients with endometriosis with or without laser-assisted zona pellucida thinning. DESIGN: Randomized controlled trial. SETTING: The study was conducted in the Obstetrics & Gynecology Department, Cairo University hospital, and two private IVF centers in Cairo & Beni-Suif from July 2015 to January 2017 upon infertile and known endometriosis patients who planned to do ICSI-ET. INTERVENTIONS: Before randomization, all patients received the same ovarian stimulation preparation, oocyte retrieval procedures, and the same intracytoplasmic sperm injection procedures...
December 6, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29212429/the-impact-of-luteinizing-hormone-supplementation-in-gonadotropin-releasing-hormone-antagonist-cycles-a-retrospective-cohort-study
#8
Wen He, Hui Lin, Jie Lv, Yanfei Wen, Liuhong Cai
The impact of exogenous luteinizing hormone (LH) supplementation to patients undergoing controlled ovarian stimulation with gonadotropin-releasing hormone (GnRH) antagonists on cycle outcomes is controversial. Here, we present a retrospective cohort study including cycles from December 2015 to December 2016. Totally 320 cycles were divided into two groups according to with or without exogenous LH supplementation. No significant differences regarding the number of retrieved oocytes, the number of good-quality embryos, and clinical pregnancy rate between the two groups were found...
December 6, 2017: Gynecological Endocrinology
https://www.readbyqxmd.com/read/29211889/reduced-live-birth-rates-after-ivf-icsi-in-women-with-previous-unilateral-oophorectomy-results-of-a-multicentre-cohort-study
#9
Tekla Lind, Jan Holte, Jan I Olofsson, Nermin Hadziosmanovic, Johannes Gudmundsson, Elizabeth Nedstrand, Mikael Lood, Lars Berglund, Kenny Rodriguez-Wallberg
STUDY QUESTION: Is there a reduced live-birth rate (LBR) after IVF/ICSI treatment in women with a previous unilateral oophorectomy (UO)? SUMMARY ANSWER: A significantly reduced LBR after IVF/ICSI was found in women with previous UO when compared with women with intact ovaries in this large multicentre cohort, both crudely and after adjustment for age, BMI, fertility centre and calendar period and regardless of whether the analysis was based on transfer of embryos in the fresh cycle only or on cumulative results including transfers using frozen-thawed embryos...
December 4, 2017: Human Reproduction
https://www.readbyqxmd.com/read/29209071/inhaled-nicotine-equivalent-to-cigarette-smoking-disrupts-systemic-and-uterine-hemodynamics-and-induces-cardiac-arrhythmia-in-pregnant-rats
#10
Xuesi M Shao, Héctor E López-Valdés, Jing Liang, Jack L Feldman
Maternal smoking with obligatory nicotine inhalation is associated with preterm delivery, low birth weight, fetal growth retardation and developmental defects. We tested the hypothesis that cigarette smoking-relevant nicotine inhalation during pregnancy impairs cardiovascular function and uterine hemodynamics with consequential fetal ischemia. Pregnant rats exposed to episodic inhaled nicotine via a novel lung alveolar region-targeted aerosol method produced nicotine pharmacokinetics resembling cigarette smoking in humans...
December 5, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29208873/correlation-between-seropositivity-of-chlamydia-trachomatis-and-tubal-and-or-pelvic-pathology-detected-by-diagnostic-laparoscopy-in-subfertile-women
#11
N Begum, S A Anwary, M Alfazzaman, Z Mahzabin, F Deeba, M A Mostafa, M Akhter, M M Rahman
This prospective observational study was carried out in the Infertility Unit, Department of Obstetrics and Gynaecology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, from February 2011 to December 2013. Sixty-nine (69) subfertile women who were seropositive for Chlamydia Trachomatis were included in this study. Inclusion criteria was patients with sub-fertility having age between 22 and 40 years, seeking infertility treatment, normal ovarian function, all normozoospermic male partner, duration of infertility ranged from 1...
October 2017: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/29207007/fertility-preservation-in-women-harboring-deleterious-brca-mutations-ready-for-prime-time
#12
Fedro Alessandro Peccatori, Giorgia Mangili, Alice Bergamini, Francesca Filippi, Fabio Martinelli, Federica Ferrari, Stefania Noli, Emanuela Rabaiotti, Massimo Candiani, Edgardo Somigliana
Fertility issues have become critical in the management and counseling of BRCA mutation carriers. In this setting four points deserve consideration. (1) Women in general lose their ability to conceive at a mean age of 41 years, thus the suggested policy of prophylactic bilateral salpingo-oophorectomy at age 40 for BRCA mutation carriers does not affect the chances of natural pregnancy. Conversely, if the procedure is chosen at 35 years old, oocyte cryopreservation prior to surgery should be considered. (2) Some evidence suggests that ovarian reserve may actually be partly reduced in BRCA mutations carriers and that the mutation may affect ovarian responsiveness to stimulation...
December 1, 2017: Human Reproduction
https://www.readbyqxmd.com/read/29205608/in-utero-aspiration-versus-expectant-management-for-anechoic-fetal-ovarian-cysts-an-open-randomized-controlled-trial
#13
Caroline Diguisto, Norbert Winer, Guillaume Benoist, Helene Laurichesse Delmas, Jerome Potin, Aurélien Binet, Hubert Lardy, Baptiste Morel, Franck Perrotin
OBJECTIVES: To assess the efficacy and safety of in utero aspiration for anechoic fetal ovarian cysts. METHODS: This multicenter, prospective, randomized open trial with two parallel groups included women from nine outpatient fetal medicine departments with singleton pregnancies ≥ 28 weeks of gestation, a female fetus with an ultrasound-diagnosed simple ovarian cyst, defined as a single fully anechoic cystic structure measuring ≥ 30 mm. They were randomly allocated to in utero cyst aspiration under ultrasound guidance or expectant management...
December 5, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29204869/estrogen-treatment-in-infertile-women-with-premature-ovarian-insufficiency-in-transitional-phase-a-retrospective-analysis
#14
Sara Pinelli, Paolo Giovanni Artini, Stefano Basile, Maria Elena Rosa Obino, Claudia Sergiampietri, Diana Giannarelli, Giovanna Simi, Vito Cela
PURPOSE: During the transitional phase of premature ovarian insufficiency (POI), sporadic resumption of ovulation is possible because of fluctuation of hormonal levels but the chance of spontaneous pregnancy is low, and the main perspective of childbearing in these women is egg donation or adoption. The purpose of the study was to verify whether treatment with estrogens in POI patients in transitional phase could reduce FSH levels and to evaluate if this pre-treatment could improve reproductive outcomes of in vitro fertilization (IVF)...
December 5, 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/29203342/effect-of-early-second-look-hysteroscopy-on-reproductive-outcomes-after-hysteroscopic-adhesiolysis-in-patients-with-intrauterine-adhesion-a-retrospective-study-in-china
#15
Wenzhi Xu, Yuxue Zhang, Yang Yang, Songying Zhang, Xiaona Lin
OBJECTIVE: The aim of this study was to assess the effect of early second-look hysteroscopy after hysteroscopic adhesiolysis for intrauterine adhesions (IUAs) on the pregnancy rate (PR) and live birth rate (LBR). STUDY DESIGN: It is a retrospective, observational study of 151 women were referred to our institution from January 2010 to January 2016. Operative hysteroscopy for treatment of IUAs and office hysteroscopic follow-up to assess IUAs. We investigated demographic characteristics, menstrual pattern, previous intrauterine surgery, reproductive history, ovarian preservation assessment, tubal patency examination, husband's semen test, obstetric parameters, and surgical variables to evaluate the effect of early second-look hysteroscopy after hysteroscopic adhesiolysis on the PR and LBR...
December 1, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/29202975/diminished-ovarian-reserve-as-measured-by-means-of-baseline-follicle-stimulating-hormone-and-antral-follicle-count-is-not-associated-with-pregnancy-loss-in-younger-in%C3%A2-vitro-fertilization-patients
#16
Lauren A Bishop, Kevin S Richter, George Patounakis, Leslie Andriani, Kimberly Moon, Kate Devine
OBJECTIVE: To assess the relationship between diminished ovarian reserve and pregnancy outcomes in a large cohort of women achieving pregnancy through in vitro fertilization (IVF). We evaluated antral follicle count (AFC) and baseline FSH as a measure of ovarian reserve. Secondarily, we assessed whether diminished ovarian reserve was associated with aneuploidy among spontaneous abortions. DESIGN: Retrospective cohort study. SETTING: Multicenter private practice...
December 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/29201422/demographic-analysis-of-a-low-resource-socioculturally-diverse-urban-community-presenting-for-infertility-care-in-a-united-states-public-hospital
#17
Jacqueline R Ho, Jacquelyn R Hoffman, Lusine Aghajanova, James F Smith, Marisela Cardenas, Christopher N Herndon
Background: Infertility is a prevalent disease of reproductive health that exerts an impact on an estimated 80 million people worldwide. For many, involuntary childlessness becomes a central and preoccupying issue in their lives, the impact of which is exacerbated by lack of access to basic care and treatment. These effects maybe further magnified among immigrant communities, a growing but highly marginalized population that has been shown in other areas of reproductive health to experience worse health outcomes and delays in access to care...
2017: Contraception and Reproductive Medicine
https://www.readbyqxmd.com/read/29199875/using-position-emission-tomography-to-investigate-hormone-mediated-neurochemical-changes-across-the-female-lifespan-implications-for-depression
#18
Rachel G Zsido, Arno Villringer, Julia Sacher
Ovarian hormones, particularly oestrogen and progesterone, undergo major fluctuations across the female lifespan. These hormone transition periods, such as the transition from pregnancy to postpartum, as well as the transition into menopause (perimenopause), are also known to be times of elevated susceptibility to depression. This study reviews how these transition periods likely influence neurochemical changes in the brain that result in disease vulnerability. While there are known associations between oestrogen/progesterone and different monoaminergic systems, the interactions and their potential implications for mood disorders are relatively unknown...
December 4, 2017: International Review of Psychiatry
https://www.readbyqxmd.com/read/29198975/improvement-of-bovine-in%C3%A2-vitro-embryo-production-by-ovarian-follicular-wave-synchronization-prior-to-ovum-pick-up
#19
F L B Cavalieri, F Morotti, M M Seneda, A H B Colombo, M A Andreazzi, I P Emanuelli, L P Rigolon
This study evaluated the effects of the synchronization of ovarian follicular wave emergence on the efficiency of in vitro embryo production. Bos indicus cows (n = 20) were divided into two groups (control vs. synchronization) and subjected to repeated ovum pick-up (OPU) sessions (8 replicates each, with an interval of 21 days in a 2 × 2 crossover design) and subsequent in vitro embryo production. Cows in the control group (n = 10) were submitted to OPU procedures without any stimulation every 21 days...
November 26, 2017: Theriogenology
https://www.readbyqxmd.com/read/29198847/first-delivery-in-a-leukemia-survivor-after-transplantation-of-cryopreserved-ovarian-tissue-evaluated-for-leukemia-cells-contamination
#20
Moran Shapira, Hila Raanani, Iris Barshack, Ninette Amariglio, Sanaz Derech-Haim, Meital Nagar Marciano, Eyal Schiff, Raoul Orvieto, Dror Meirow
OBJECTIVE: To describe a successful autologous ovarian tissue re-transplantation in a sterile leukemia survivor after evaluation for minimal residual disease and provide a review of the current literature. DESIGN: Presentation of a carefully designed workup taken to evaluate tissue for minimal residual disease, its limitations, and applicability to other patients. To date, there have not been any publications of auto-transplantations in leukemia survivors, owing to an estimated high risk for malignancy induction...
November 29, 2017: Fertility and Sterility
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