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https://www.readbyqxmd.com/read/29752172/social-determinants-of-health-are-associated-with-markers-of-renal-injury-in-adolescents-with-type-1-diabetes
#1
Laura A M Cummings, Antoine Clarke, Etienne Sochett, Denis Daneman, David Z Cherney, Heather N Reich, James W Scholey, David B Dunger, Farid H Mahmud
OBJECTIVE: To examine the relationship between the social determinants of health and markers of early renal injury in adolescent patients with type 1 diabetes (T1D). STUDY DESIGN: Renal outcomes included estimated glomerular filtration rate (eGFR) and albumin-creatinine excretion ratio (ACR). Differences in urinary and serum inflammatory markers also were assessed in relation to social determinants of health. Regression analysis was used to evaluate the association between the Ontario Marginalization Index (ON-Marg) as a measure of the social determinants of health, patient characteristics, ACR, eGFR, and renal filtration status (hyperfiltration vs normofiltration)...
May 8, 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/29692980/leveraging-national-cancer-institute-programmatic-collaboration-for-uterine-cervix-cancer-patient-accrual-in-puerto-rico
#2
Charles A Kunos, Holly A Massett, Annette Galassi, Joan L Walker, Marge J Good, Luis Báez Díaz, Worta McCaskill-Stevens
Women in the U.S. Commonwealth of Puerto Rico (PR) have a higher age-adjusted incidence rate for uterine cervix cancer than the U.S. mainland as well as substantial access and economic barriers to cancer care. The National Cancer Institute (NCI) funds a Minority/Underserved NCI Community Oncology Research Program in PR (PRNCORP) as part of a national network of community-based health-care systems to conduct multisite cancer clinical trials in diverse populations. Participation by the PRNCORP in NCI's uterine cervix cancer clinical trials, however, has remained limited...
2018: Frontiers in Oncology
https://www.readbyqxmd.com/read/29691964/transition-to-adult-diabetes-care-in-germany-high-risk-for-acute-complications-and-declining-metabolic-control-during-the-transition-phase
#3
T M Kapellen, S Müther, A Schwandt, J Grulich-Henn, B Schenk, K O Schwab, W Marg, R W Holl
OBJECTIVE: There is evidence that transition from pediatric to adult health care is frequently associated with deterioration of health in youths with type 1 diabetes (T1D). The aim of this study was to compare metabolic control, acute complications and microvascular complications in adolescents and young adults before and after transfer to an adult treatment center with respect to the time between first visit in the adult center and last visit in pediatric treatment. METHODS: All data were collected during routine care and retrieved from the German/Austrian DPV database...
April 25, 2018: Pediatric Diabetes
https://www.readbyqxmd.com/read/29690219/a-checklist-of-the-helminth-parasites-of-sympatric-rodents-from-two-mayan-villages-in-yucat%C3%A3-n-m%C3%A3-xico
#4
JesÚs Alonso Panti-May, MarÍa Celina Digiani, Eduardo Emir Palomo-Arjona, Yessica Margely Gurubel-gonzÁlez, Graciela T Navone, Carlos Machain- Williams, Silvia F HernÁndez-Betancourt, MarÍa Del Rosario Robles
In this survey, 19 species of helminths including Cestoda (Davaineidae, Hymenolepididae, and Taeniidae), Acanthocephala (Oligacanthorhynchidae), and Nematoda (Trichuridae, Ornithostrongylidae, Heligmonellidae, Oxyuridae, and Gongylonematidae) from Rattus rattus, Mus musculus, Sigmodon toltecus, Heteromys gaumeri, and Peromyscus yucatanicus in two Mayan villages in Yucatán, México, were recorded. Ten species of helminths were collected in both localities. The highest species richness was recorded in R. rattus from Xkalakdzonot (6 taxa)...
April 5, 2018: Zootaxa
https://www.readbyqxmd.com/read/29558216/fanconi-syndrome-in-irish-wolfhound-siblings
#5
Nick X Bommer, Serena E Brownlie, Linda R Morrison, Marge L Chandler, James W Simpson
Three juvenile male Irish wolfhound littermates presented with marked polyuria and polydipsia. The four female siblings were apparently unaffected. Diagnostic testing revealed glucosuria with normoglycemia, generalized aminoaciduria, hypokalemia and metabolic acidosis consistent with Fanconi syndrome. Renal ultrasonographic and histologic findings are presented. Cases were managed with a supplementation regimen based on a treatment protocol for Fanconi syndrome in basenjis. These dogs did not have angular limb deformities as documented previously in juvenile canine siblings with Fanconi syndrome...
March 20, 2018: Journal of the American Animal Hospital Association
https://www.readbyqxmd.com/read/29457742/response-to-progesterone-for-preventing-pregnancy-termination-after-initiation-of-medical-abortion-with-mifepristone-what-s-the-real-point-here
#6
LETTER
Marge Berer
No abstract text is available yet for this article.
April 2018: European Journal of Contraception & Reproductive Health Care
https://www.readbyqxmd.com/read/29457736/answer-to-the-letter-of-marge-berer
#7
LETTER
Johannes Bitzer
No abstract text is available yet for this article.
April 2018: European Journal of Contraception & Reproductive Health Care
https://www.readbyqxmd.com/read/29385480/genotype-%C3%A3-prenatal-and-post-weaning-nutritional-environment-interaction-in-a-composite-beef-cattle-breed-using-reaction-norms-and-a-multi-trait-model
#8
El Hamidi Hay, Andy Roberts
Environmental effects have been shown to influence several economically important traits in beef cattle. In this study, genotype × nutritional environment interaction has been evaluated in a composite beef cattle breed (50% Red Angus, 25% Charolais, 25% Tarentaise). Four nutritional environments (marginal-restricted [MARG-RES], marginal-control [MARG-CTRL], adequate-restricted [ADEQ-RES], and adequate-control [ADEQ-CTRL]) were created based on two levels of winter supplement provided to dams grazing winter range during gestation (MARG and ADEQ) and two levels of input to offspring during post-weaning development (RES and CTRL)...
March 6, 2018: Journal of Animal Science
https://www.readbyqxmd.com/read/29311080/mycobacterium-abscessus-smooth-and-rough-morphotypes-form-antimicrobial-tolerant-biofilm-phenotypes-but-are-killed-by-acetic-acid
#9
Gillian Clary, Smitha J Sasindran, Nathan Nesbitt, Laurel Mason, Sara Cole, Abul Azad, Karen McCoy, Larry S Schlesinger, Luanne Hall-Stoodley
Mycobacterium abscessus has emerged as an important pathogen in people with chronic inflammatory lung diseases such as cystic fibrosis, and recent reports suggest that it may be transmissible by fomites. M. abscessus exhibits two major colony morphology variants: a smooth morphotype ( MaSm ) and a rough morphotype ( MaRg ). Biofilm formation, prolonged intracellular survival, and colony variant diversity can each contribute to the persistence of M. abscessus and other bacterial pathogens in chronic pulmonary diseases...
March 2018: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/29303803/postoperative-eras-interventions-have-the-greatest-impact-on-optimal-recovery-experience-with-implementation-of-eras-across-multiple-hospitals
#10
Mary-Anne Aarts, Ori D Rotstein, Emily A Pearsall, J Charles Victor, Allan Okrainec, Marg McKenzie, Stuart A McCluskey, Lesley Gotlib Conn, Robin S McLeod
BACKGROUND: Enhanced recovery after surgery (ERAS) programs incorporate evidence-based practices to minimize perioperative stress, gut dysfunction, and promote early recovery. However, it is unknown which components have the greatest impact. OBJECTIVE: This study aims to determine which components of ERAS programs have the largest impact on recovery for patients undergoing colorectal surgery. METHODS: An iERAS program was implemented in 15 academic hospitals...
January 4, 2018: Annals of Surgery
https://www.readbyqxmd.com/read/29299141/optimization-of-the-margin-expanded-from-the-clinical-to-the-planned-target-volume-during-intensity-modulated-radiotherapy-for-nasopharyngeal-carcinoma
#11
Wang Fangzheng, Sun Quanquan, Jiang Chuner, Ye Zhimin, Yang Shuangyan, Yu Huanhuan, Shi Jianfang, Masoto Sakamoto, Qin Weifeng, Fu Zhenfu, Jiang Yangming, Wang Yuezhen
During the radiotherapy process, the emergence of set-up errors is nearly inevitable. Because set-up errors were not detected and corrected daily, planned target volumes were formed by expanding the clinical target volume according to each unit's experience. We optimized the margins of clinical and planned target volumes during administration of intensity-modulated radiotherapy for nasopharyngeal carcinoma. A total of 72 patients newly diagnosed with non-metastatic nasopharyngeal carcinoma and treated with Tomotherapy were prospectively enrolled in the study...
December 15, 2017: Oncotarget
https://www.readbyqxmd.com/read/29288632/association-of-vascular-indices-with-novel-circulating-biomarkers-as-prognostic-factors-for-cardiovascular-complications-in-patients-with-type-2-diabetes-mellitus
#12
Katerina K Naka, Katerina Papathanassiou, Aris Bechlioulis, Konstantinos Pappas, Stelios Tigas, Dimitrios Makriyiannis, Sophia Antoniou, Nikolaos Kazakos, Alexandra Margeli, Ioannis Papassotiriou, Agathocles Tsatsoulis, Lampros K Michalis
BACKGROUND: The pathophysiology of atherosclerosis in type 2 diabetes mellitus (T2DM) is multifactorial. The association of vascular indices with circulating biomarkers of inflammation and insulin resistance and their role in the long-term cardiovascular prognosis in T2DM patients were currently investigated. PATIENTS AND METHODS: Patients with T2DM and poor glycemic control without known cardiovascular diseases (n=119) at baseline were enrolled and followed for about 9years...
March 2018: Clinical Biochemistry
https://www.readbyqxmd.com/read/29242083/medical-abortion-pills-have-the-potential-to-change-everything-about-abortion
#13
EDITORIAL
Marge Berer, Lesley Hoggart
No abstract text is available yet for this article.
February 2018: Contraception
https://www.readbyqxmd.com/read/29171132/structured-education-to-improve-primary-care-management-of-headache-how-long-do-the-benefits-last-a-follow-up-observational-study
#14
M Braschinsky, S Haldre, M Kals, M Arge, B Saar, M Niibek, Z Katsarava, T J Steiner
BACKGROUND AND PURPOSE: Our earlier study showed that structured education of general practitioners (GPs) improved their practice in headache management. Here the duration of this effect was assessed. METHODS: In a follow-up observational study in southern Estonia, subjects were the same six GPs as previously, managing patients presenting with headache as the main complaint. Data reflecting their practice were collected prospectively during a 1-year period commencing 2 years after the educational intervention...
March 2018: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/29144599/assessing-social-values-for-california-s-efforts-to-reduce-the-overuse-of-unnecessary-medical-care
#15
Susan L Perez, Desiree Backman, Marge Ginsburg
BACKGROUND: A partnership of large health-care purchasers created a workgroup to reduce the overuse of harmful and wasteful medical care in California. OBJECTIVE: Employ a civic engagement process to identify the social values important to the public in considering different strategies to reduce overuse. INTERVENTION: Use of deliberation techniques for 3 case examples that explore possible strategies: physician oversight, physician compensation, increased patient cost-sharing or taking no definitive action...
November 16, 2017: Health Expectations: An International Journal of Public Participation in Health Care and Health Policy
https://www.readbyqxmd.com/read/29142045/rapid-assay-for-detection-of-the-epidemiologically-important-central-asian-russian-strain-of-the-mycobacterium-tuberculosis-beijing-genotype
#16
LETTER
Igor Mokrousov, Ekaterina Chernyaeva, Anna Vyazovaya, Yuriy Skiba, Natalia Solovieva, Violeta Valcheva, Klavdia Levina, Natalya Malakhova, Wei-Wei Jiao, Lia Lima Gomes, Philip N Suffys, Marge Kütt, Nagima Aitkhozhina, A-Dong Shen, Olga Narvskaya, Viacheslav Zhuravlev
No abstract text is available yet for this article.
February 2018: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/29119620/identification-of-oestrogen-progesterone-receptor-and-human-epidermal-growth-factor-receptor-2-expression-in-mediastinal-metastases-of-breast-cancer-obtained-by-endobronchial-ultrasound-guided-transbronchial-needle-aspiration
#17
P Serra, J Sanz-Santos, E Castellà, B Cirauqui, F Andreo, M Llatjós, M Avila, M Margelí, L Serrano, C Centeno, V Quiroga, M Torky, J Ruiz-Manzano
BACKGROUND: In breast cancer patients, the expression statuses of oestrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2) are crucial in the choice of treatment. Receptor expression in metastatic lesions can differ from the primary tumour. The aim of our study was to analyse the utility of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) to obtain samples allowing the identification of ER, PR and HER2 expression in patients with mediastinal metastases of breast cancer...
February 2018: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://www.readbyqxmd.com/read/29093447/e-cadherin-integrates-mechanotransduction-and-egfr-signaling-to-control-junctional-tissue-polarization-and-tight-junction-positioning
#18
Matthias Rübsam, Aaron F Mertz, Akiharu Kubo, Susanna Marg, Christian Jüngst, Gladiola Goranci-Buzhala, Astrid C Schauss, Valerie Horsley, Eric R Dufresne, Markus Moser, Wolfgang Ziegler, Masayuki Amagai, Sara A Wickström, Carien M Niessen
Generation of a barrier in multi-layered epithelia like the epidermis requires restricted positioning of functional tight junctions (TJ) to the most suprabasal viable layer. This positioning necessitates tissue-level polarization of junctions and the cytoskeleton through unknown mechanisms. Using quantitative whole-mount imaging, genetic ablation, and traction force microscopy and atomic force microscopy, we find that ubiquitously localized E-cadherin coordinates tissue polarization of tension-bearing adherens junction (AJ) and F-actin organization to allow formation of an apical TJ network only in the uppermost viable layer...
November 1, 2017: Nature Communications
https://www.readbyqxmd.com/read/29092043/emerging-resistant-clones-of-mycobacterium-tuberculosis-in-a-spatiotemporal-context
#19
Anna Vyazovaya, Klavdia Levina, Viacheslav Zhuravlev, Piret Viiklepp, Marge Kütt, Igor Mokrousov
Objectives: We assessed the genetic structure of the Mycobacterium tuberculosis population in Estonia with a special focus on major epidemic/endemic clones and drug resistance determinants. We investigated the hypothesis of the decisive impact of massive human influx on the locally circulating genotypes. Estonia received a mass immigration from Russia during 1945-90 followed by enhanced interaction with the EU since 1991. Methods: The study sample included M. tuberculosis isolates from patients newly diagnosed with TB in 2014 in North Estonia (including the capital Tallinn)...
February 1, 2018: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/28990748/cal-mediconnect-enrollment-why-are-dual-eligible-consumers-in-los-angeles-county-opting-out
#20
Kate McBride, Ana Reynoso, Tiffany Alunan, Brenda Gutierrez, Adrien Bacong, Marge Moon, Anastasia Bacigalupo, A E Benjamin, Steven P. Wallace, Kathryn G Kietzman
Los Angeles County has the state’s lowest rate of consumer enrollment in Cal MediConnect, a program that is responsible for the delivery and coordination of medical, behavioral health, and long-term services and support benefits for individuals who are dually eligible for Medicare and Medi-Cal. This policy brief examines the factors that influence consumer decisions and may contribute to low enrollment rates. Influential factors include consumer knowledge of health care options, perception of choice, and disruption of existing care...
September 1, 2017: Policy Brief
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